Amino acid dipepetide frequency for Changjiang tombus-like virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.111AlaAla: 14.111 ± 4.482
0.941AlaCys: 0.941 ± 0.854
9.407AlaAsp: 9.407 ± 4.127
3.763AlaGlu: 3.763 ± 1.427
7.526AlaPhe: 7.526 ± 1.924
8.467AlaGly: 8.467 ± 2.182
2.822AlaHis: 2.822 ± 1.854
3.763AlaIle: 3.763 ± 2.863
5.644AlaLys: 5.644 ± 0.717
12.23AlaLeu: 12.23 ± 2.605
0.941AlaMet: 0.941 ± 0.564
5.644AlaAsn: 5.644 ± 2.657
3.763AlaPro: 3.763 ± 1.513
0.941AlaGln: 0.941 ± 0.854
5.644AlaArg: 5.644 ± 1.299
6.585AlaSer: 6.585 ± 2.371
7.526AlaThr: 7.526 ± 2.838
14.111AlaVal: 14.111 ± 7.513
0.941AlaTrp: 0.941 ± 0.854
3.763AlaTyr: 3.763 ± 0.21
0.0AlaXaa: 0.0 ± 0.0
Cys
2.822CysAla: 2.822 ± 1.884
0.0CysCys: 0.0 ± 0.0
0.941CysAsp: 0.941 ± 0.564
0.0CysGlu: 0.0 ± 0.0
0.941CysPhe: 0.941 ± 0.564
2.822CysGly: 2.822 ± 1.884
0.0CysHis: 0.0 ± 0.0
1.881CysIle: 1.881 ± 0.894
0.941CysLys: 0.941 ± 0.564
1.881CysLeu: 1.881 ± 0.783
0.0CysMet: 0.0 ± 0.0
0.941CysAsn: 0.941 ± 0.854
0.941CysPro: 0.941 ± 1.065
0.941CysGln: 0.941 ± 0.564
1.881CysArg: 1.881 ± 0.783
1.881CysSer: 1.881 ± 0.974
1.881CysThr: 1.881 ± 1.128
4.704CysVal: 4.704 ± 2.021
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.526AspAla: 7.526 ± 0.797
0.941AspCys: 0.941 ± 0.564
2.822AspAsp: 2.822 ± 0.422
2.822AspGlu: 2.822 ± 1.854
1.881AspPhe: 1.881 ± 0.783
2.822AspGly: 2.822 ± 1.693
0.0AspHis: 0.0 ± 0.0
0.941AspIle: 0.941 ± 0.564
1.881AspLys: 1.881 ± 0.894
1.881AspLeu: 1.881 ± 0.783
1.881AspMet: 1.881 ± 0.894
3.763AspAsn: 3.763 ± 0.21
6.585AspPro: 6.585 ± 1.249
1.881AspGln: 1.881 ± 0.783
2.822AspArg: 2.822 ± 1.854
0.941AspSer: 0.941 ± 0.854
0.941AspThr: 0.941 ± 1.065
1.881AspVal: 1.881 ± 0.783
0.0AspTrp: 0.0 ± 0.0
1.881AspTyr: 1.881 ± 1.128
0.0AspXaa: 0.0 ± 0.0
Glu
2.822GluAla: 2.822 ± 1.693
0.941GluCys: 0.941 ± 0.564
3.763GluAsp: 3.763 ± 1.427
2.822GluGlu: 2.822 ± 1.049
2.822GluPhe: 2.822 ± 1.049
2.822GluGly: 2.822 ± 1.49
2.822GluHis: 2.822 ± 1.693
1.881GluIle: 1.881 ± 0.974
1.881GluLys: 1.881 ± 1.128
1.881GluLeu: 1.881 ± 0.894
0.941GluMet: 0.941 ± 1.065
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
1.881GluGln: 1.881 ± 0.783
2.822GluArg: 2.822 ± 1.049
0.941GluSer: 0.941 ± 0.854
1.881GluThr: 1.881 ± 1.128
3.763GluVal: 3.763 ± 0.21
2.822GluTrp: 2.822 ± 0.422
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.763PheAla: 3.763 ± 1.419
0.941PheCys: 0.941 ± 0.564
0.941PheAsp: 0.941 ± 0.564
0.0PheGlu: 0.0 ± 0.0
2.822PhePhe: 2.822 ± 1.049
6.585PheGly: 6.585 ± 1.104
0.0PheHis: 0.0 ± 0.0
1.881PheIle: 1.881 ± 0.783
1.881PheLys: 1.881 ± 1.128
5.644PheLeu: 5.644 ± 0.717
1.881PheMet: 1.881 ± 0.894
0.941PheAsn: 0.941 ± 0.564
0.941PhePro: 0.941 ± 0.564
1.881PheGln: 1.881 ± 0.974
1.881PheArg: 1.881 ± 1.708
1.881PheSer: 1.881 ± 1.128
1.881PheThr: 1.881 ± 0.894
2.822PheVal: 2.822 ± 1.049
0.941PheTrp: 0.941 ± 0.564
0.941PheTyr: 0.941 ± 1.065
0.0PheXaa: 0.0 ± 0.0
Gly
12.23GlyAla: 12.23 ± 4.082
3.763GlyCys: 3.763 ± 1.427
4.704GlyAsp: 4.704 ± 1.9
1.881GlyGlu: 1.881 ± 1.128
2.822GlyPhe: 2.822 ± 1.065
4.704GlyGly: 4.704 ± 1.391
0.941GlyHis: 0.941 ± 0.854
7.526GlyIle: 7.526 ± 1.487
0.941GlyLys: 0.941 ± 0.564
10.348GlyLeu: 10.348 ± 2.498
2.822GlyMet: 2.822 ± 0.503
2.822GlyAsn: 2.822 ± 1.693
0.941GlyPro: 0.941 ± 1.065
2.822GlyGln: 2.822 ± 0.422
5.644GlyArg: 5.644 ± 2.163
4.704GlySer: 4.704 ± 1.107
0.941GlyThr: 0.941 ± 0.854
9.407GlyVal: 9.407 ± 3.638
0.941GlyTrp: 0.941 ± 1.065
3.763GlyTyr: 3.763 ± 1.566
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.941HisGly: 0.941 ± 0.854
0.0HisHis: 0.0 ± 0.0
0.941HisIle: 0.941 ± 1.065
0.941HisLys: 0.941 ± 0.564
0.0HisLeu: 0.0 ± 0.0
1.881HisMet: 1.881 ± 0.894
0.941HisAsn: 0.941 ± 0.564
1.881HisPro: 1.881 ± 0.783
0.0HisGln: 0.0 ± 0.0
2.822HisArg: 2.822 ± 1.049
1.881HisSer: 1.881 ± 0.894
0.941HisThr: 0.941 ± 0.564
0.941HisVal: 0.941 ± 0.564
0.0HisTrp: 0.0 ± 0.0
0.941HisTyr: 0.941 ± 0.854
0.0HisXaa: 0.0 ± 0.0
Ile
4.704IleAla: 4.704 ± 1.391
0.0IleCys: 0.0 ± 0.0
1.881IleAsp: 1.881 ± 0.974
2.822IleGlu: 2.822 ± 1.065
0.941IlePhe: 0.941 ± 0.564
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
0.941IleIle: 0.941 ± 1.065
0.0IleLys: 0.0 ± 0.0
2.822IleLeu: 2.822 ± 0.422
2.822IleMet: 2.822 ± 1.065
1.881IleAsn: 1.881 ± 1.708
3.763IlePro: 3.763 ± 0.21
1.881IleGln: 1.881 ± 0.783
6.585IleArg: 6.585 ± 0.355
3.763IleSer: 3.763 ± 1.007
1.881IleThr: 1.881 ± 0.894
0.941IleVal: 0.941 ± 1.065
0.0IleTrp: 0.0 ± 0.0
0.941IleTyr: 0.941 ± 1.065
0.0IleXaa: 0.0 ± 0.0
Lys
4.704LysAla: 4.704 ± 1.866
0.0LysCys: 0.0 ± 0.0
3.763LysAsp: 3.763 ± 1.427
0.0LysGlu: 0.0 ± 0.0
0.941LysPhe: 0.941 ± 0.564
2.822LysGly: 2.822 ± 1.693
0.0LysHis: 0.0 ± 0.0
0.941LysIle: 0.941 ± 0.854
2.822LysLys: 2.822 ± 1.49
2.822LysLeu: 2.822 ± 1.049
0.941LysMet: 0.941 ± 1.065
1.881LysAsn: 1.881 ± 1.708
2.822LysPro: 2.822 ± 1.065
0.941LysGln: 0.941 ± 1.065
0.0LysArg: 0.0 ± 0.0
2.822LysSer: 2.822 ± 1.538
2.822LysThr: 2.822 ± 1.065
5.644LysVal: 5.644 ± 2.413
3.763LysTrp: 3.763 ± 2.257
0.941LysTyr: 0.941 ± 0.564
0.0LysXaa: 0.0 ± 0.0
Leu
6.585LeuAla: 6.585 ± 1.393
0.0LeuCys: 0.0 ± 0.0
4.704LeuAsp: 4.704 ± 2.286
5.644LeuGlu: 5.644 ± 2.552
1.881LeuPhe: 1.881 ± 0.974
5.644LeuGly: 5.644 ± 1.299
0.941LeuHis: 0.941 ± 0.564
5.644LeuIle: 5.644 ± 1.518
3.763LeuLys: 3.763 ± 1.513
6.585LeuLeu: 6.585 ± 1.393
0.0LeuMet: 0.0 ± 0.522
1.881LeuAsn: 1.881 ± 0.974
2.822LeuPro: 2.822 ± 1.065
3.763LeuGln: 3.763 ± 1.007
7.526LeuArg: 7.526 ± 2.99
3.763LeuSer: 3.763 ± 1.007
5.644LeuThr: 5.644 ± 0.717
5.644LeuVal: 5.644 ± 0.717
0.941LeuTrp: 0.941 ± 1.065
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
5.644MetAla: 5.644 ± 0.843
0.941MetCys: 0.941 ± 0.564
0.0MetAsp: 0.0 ± 0.0
2.822MetGlu: 2.822 ± 1.884
0.941MetPhe: 0.941 ± 1.065
0.941MetGly: 0.941 ± 0.854
0.941MetHis: 0.941 ± 0.564
0.941MetIle: 0.941 ± 1.065
3.763MetLys: 3.763 ± 1.788
0.941MetLeu: 0.941 ± 0.564
0.941MetMet: 0.941 ± 1.065
1.881MetAsn: 1.881 ± 1.128
0.941MetPro: 0.941 ± 0.854
0.941MetGln: 0.941 ± 0.564
1.881MetArg: 1.881 ± 0.894
1.881MetSer: 1.881 ± 0.783
0.941MetThr: 0.941 ± 0.854
3.763MetVal: 3.763 ± 1.788
0.0MetTrp: 0.0 ± 0.0
1.881MetTyr: 1.881 ± 0.974
0.0MetXaa: 0.0 ± 0.0
Asn
5.644AsnAla: 5.644 ± 1.518
0.941AsnCys: 0.941 ± 0.564
0.941AsnAsp: 0.941 ± 0.854
0.941AsnGlu: 0.941 ± 0.854
0.0AsnPhe: 0.0 ± 0.0
4.704AsnGly: 4.704 ± 1.782
0.0AsnHis: 0.0 ± 0.0
0.941AsnIle: 0.941 ± 0.854
3.763AsnLys: 3.763 ± 0.21
4.704AsnLeu: 4.704 ± 1.782
0.941AsnMet: 0.941 ± 1.065
4.704AsnAsn: 4.704 ± 2.021
2.822AsnPro: 2.822 ± 1.538
0.0AsnGln: 0.0 ± 0.0
0.941AsnArg: 0.941 ± 0.564
2.822AsnSer: 2.822 ± 1.065
5.644AsnThr: 5.644 ± 2.348
2.822AsnVal: 2.822 ± 1.693
0.0AsnTrp: 0.0 ± 0.0
1.881AsnTyr: 1.881 ± 0.783
0.0AsnXaa: 0.0 ± 0.0
Pro
7.526ProAla: 7.526 ± 2.74
2.822ProCys: 2.822 ± 1.065
0.941ProAsp: 0.941 ± 0.564
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
5.644ProGly: 5.644 ± 1.82
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
0.0ProLys: 0.0 ± 0.0
2.822ProLeu: 2.822 ± 1.538
0.941ProMet: 0.941 ± 1.065
2.822ProAsn: 2.822 ± 1.538
3.763ProPro: 3.763 ± 2.257
0.941ProGln: 0.941 ± 1.065
7.526ProArg: 7.526 ± 1.6
2.822ProSer: 2.822 ± 1.065
2.822ProThr: 2.822 ± 1.049
5.644ProVal: 5.644 ± 2.552
0.941ProTrp: 0.941 ± 1.065
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.704GlnAla: 4.704 ± 1.391
0.941GlnCys: 0.941 ± 0.564
1.881GlnAsp: 1.881 ± 1.708
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
3.763GlnGly: 3.763 ± 1.419
0.941GlnHis: 0.941 ± 0.564
1.881GlnIle: 1.881 ± 1.128
0.0GlnLys: 0.0 ± 0.0
1.881GlnLeu: 1.881 ± 0.974
0.0GlnMet: 0.0 ± 0.0
1.881GlnAsn: 1.881 ± 1.128
2.822GlnPro: 2.822 ± 0.422
0.941GlnGln: 0.941 ± 0.564
1.881GlnArg: 1.881 ± 0.783
0.941GlnSer: 0.941 ± 0.564
0.0GlnThr: 0.0 ± 0.0
1.881GlnVal: 1.881 ± 0.783
0.941GlnTrp: 0.941 ± 0.854
0.941GlnTyr: 0.941 ± 1.065
0.0GlnXaa: 0.0 ± 0.0
Arg
9.407ArgAla: 9.407 ± 2.214
3.763ArgCys: 3.763 ± 2.863
2.822ArgAsp: 2.822 ± 1.884
4.704ArgGlu: 4.704 ± 1.866
5.644ArgPhe: 5.644 ± 2.098
5.644ArgGly: 5.644 ± 2.163
0.0ArgHis: 0.0 ± 0.0
1.881ArgIle: 1.881 ± 1.708
0.941ArgLys: 0.941 ± 0.564
4.704ArgLeu: 4.704 ± 1.107
2.822ArgMet: 2.822 ± 0.422
3.763ArgAsn: 3.763 ± 1.513
0.941ArgPro: 0.941 ± 0.564
1.881ArgGln: 1.881 ± 1.128
5.644ArgArg: 5.644 ± 1.518
3.763ArgSer: 3.763 ± 2.224
1.881ArgThr: 1.881 ± 0.974
11.289ArgVal: 11.289 ± 1.709
0.941ArgTrp: 0.941 ± 0.564
0.941ArgTyr: 0.941 ± 0.564
0.0ArgXaa: 0.0 ± 0.0
Ser
6.585SerAla: 6.585 ± 0.355
0.0SerCys: 0.0 ± 0.0
0.941SerAsp: 0.941 ± 0.564
0.941SerGlu: 0.941 ± 0.854
5.644SerPhe: 5.644 ± 0.717
10.348SerGly: 10.348 ± 4.473
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
4.704SerLys: 4.704 ± 1.782
1.881SerLeu: 1.881 ± 1.128
2.822SerMet: 2.822 ± 0.422
0.941SerAsn: 0.941 ± 0.854
3.763SerPro: 3.763 ± 1.007
0.941SerGln: 0.941 ± 0.854
6.585SerArg: 6.585 ± 1.286
1.881SerSer: 1.881 ± 1.708
1.881SerThr: 1.881 ± 0.894
3.763SerVal: 3.763 ± 0.21
0.0SerTrp: 0.0 ± 0.0
1.881SerTyr: 1.881 ± 1.128
0.0SerXaa: 0.0 ± 0.0
Thr
7.526ThrAla: 7.526 ± 2.014
0.941ThrCys: 0.941 ± 0.564
0.941ThrAsp: 0.941 ± 0.564
1.881ThrGlu: 1.881 ± 0.783
0.0ThrPhe: 0.0 ± 0.0
5.644ThrGly: 5.644 ± 1.299
0.941ThrHis: 0.941 ± 1.065
0.941ThrIle: 0.941 ± 1.065
0.0ThrLys: 0.0 ± 0.0
2.822ThrLeu: 2.822 ± 1.065
3.763ThrMet: 3.763 ± 0.21
2.822ThrAsn: 2.822 ± 1.065
2.822ThrPro: 2.822 ± 0.422
0.941ThrGln: 0.941 ± 0.564
2.822ThrArg: 2.822 ± 1.884
4.704ThrSer: 4.704 ± 0.74
3.763ThrThr: 3.763 ± 1.007
7.526ThrVal: 7.526 ± 1.81
0.0ThrTrp: 0.0 ± 0.0
0.941ThrTyr: 0.941 ± 1.065
0.0ThrXaa: 0.0 ± 0.0
Val
7.526ValAla: 7.526 ± 2.838
5.644ValCys: 5.644 ± 2.163
2.822ValAsp: 2.822 ± 1.049
6.585ValGlu: 6.585 ± 2.441
5.644ValPhe: 5.644 ± 2.348
5.644ValGly: 5.644 ± 1.299
4.704ValHis: 4.704 ± 0.74
3.763ValIle: 3.763 ± 1.513
5.644ValLys: 5.644 ± 2.098
1.881ValLeu: 1.881 ± 0.894
4.704ValMet: 4.704 ± 1.782
3.763ValAsn: 3.763 ± 1.566
3.763ValPro: 3.763 ± 1.947
0.941ValGln: 0.941 ± 0.564
4.704ValArg: 4.704 ± 1.107
4.704ValSer: 4.704 ± 1.107
6.585ValThr: 6.585 ± 1.286
7.526ValVal: 7.526 ± 1.81
2.822ValTrp: 2.822 ± 1.065
5.644ValTyr: 5.644 ± 0.717
0.0ValXaa: 0.0 ± 0.0
Trp
0.941TrpAla: 0.941 ± 1.065
0.941TrpCys: 0.941 ± 0.564
1.881TrpAsp: 1.881 ± 0.783
0.941TrpGlu: 0.941 ± 0.564
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.941TrpIle: 0.941 ± 0.564
0.941TrpLys: 0.941 ± 0.854
3.763TrpLeu: 3.763 ± 1.788
0.941TrpMet: 0.941 ± 0.794
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.881TrpGln: 1.881 ± 0.783
1.881TrpArg: 1.881 ± 1.128
0.941TrpSer: 0.941 ± 0.564
0.0TrpThr: 0.0 ± 0.0
0.941TrpVal: 0.941 ± 0.854
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.763TyrAla: 3.763 ± 0.21
0.941TyrCys: 0.941 ± 0.854
0.0TyrAsp: 0.0 ± 0.0
0.941TyrGlu: 0.941 ± 0.854
0.0TyrPhe: 0.0 ± 0.0
4.704TyrGly: 4.704 ± 0.74
0.0TyrHis: 0.0 ± 0.0
0.941TyrIle: 0.941 ± 1.065
0.941TyrLys: 0.941 ± 0.564
2.822TyrLeu: 2.822 ± 1.538
0.0TyrMet: 0.0 ± 0.0
1.881TyrAsn: 1.881 ± 1.128
1.881TyrPro: 1.881 ± 0.783
1.881TyrGln: 1.881 ± 2.131
1.881TyrArg: 1.881 ± 0.894
1.881TyrSer: 1.881 ± 0.783
1.881TyrThr: 1.881 ± 0.894
0.0TyrVal: 0.0 ± 0.0
0.941TyrTrp: 0.941 ± 0.564
2.822TyrTyr: 2.822 ± 1.884
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1064 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski