Amino acid dipepetide frequency for Ornithinibacillus sp. L9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.449AlaAla: 4.449 ± 0.069	0.51AlaCys: 0.51 ± 0.022	2.971AlaAsp: 2.971 ± 0.062	4.293AlaGlu: 4.293 ± 0.081	3.11AlaPhe: 3.11 ± 0.059	4.511AlaGly: 4.511 ± 0.071	1.134AlaHis: 1.134 ± 0.032	5.916AlaIle: 5.916 ± 0.087	4.296AlaLys: 4.296 ± 0.066	6.362AlaLeu: 6.362 ± 0.078	1.844AlaMet: 1.844 ± 0.044	2.894AlaAsn: 2.894 ± 0.047	1.861AlaPro: 1.861 ± 0.042	1.894AlaGln: 1.894 ± 0.04	2.242AlaArg: 2.242 ± 0.046	3.737AlaSer: 3.737 ± 0.062	3.49AlaThr: 3.49 ± 0.056	4.755AlaVal: 4.755 ± 0.069	0.62AlaTrp: 0.62 ± 0.023	2.289AlaTyr: 2.289 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.341CysAla: 0.341 ± 0.017	0.072CysCys: 0.072 ± 0.008	0.376CysAsp: 0.376 ± 0.02	0.386CysGlu: 0.386 ± 0.021	0.27CysPhe: 0.27 ± 0.016	0.574CysGly: 0.574 ± 0.022	0.163CysHis: 0.163 ± 0.012	0.471CysIle: 0.471 ± 0.02	0.365CysLys: 0.365 ± 0.02	0.577CysLeu: 0.577 ± 0.027	0.162CysMet: 0.162 ± 0.013	0.288CysAsn: 0.288 ± 0.017	0.307CysPro: 0.307 ± 0.019	0.188CysGln: 0.188 ± 0.014	0.243CysArg: 0.243 ± 0.015	0.447CysSer: 0.447 ± 0.021	0.337CysThr: 0.337 ± 0.016	0.36CysVal: 0.36 ± 0.021	0.062CysTrp: 0.062 ± 0.007	0.243CysTyr: 0.243 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.133AspAla: 3.133 ± 0.058	0.33AspCys: 0.33 ± 0.017	3.018AspAsp: 3.018 ± 0.07	4.936AspGlu: 4.936 ± 0.078	2.478AspPhe: 2.478 ± 0.051	3.466AspGly: 3.466 ± 0.06	1.373AspHis: 1.373 ± 0.038	4.546AspIle: 4.546 ± 0.063	3.159AspLys: 3.159 ± 0.06	5.018AspLeu: 5.018 ± 0.076	1.488AspMet: 1.488 ± 0.037	2.153AspAsn: 2.153 ± 0.049	2.289AspPro: 2.289 ± 0.058	2.396AspGln: 2.396 ± 0.051	2.296AspArg: 2.296 ± 0.051	2.857AspSer: 2.857 ± 0.054	2.739AspThr: 2.739 ± 0.055	4.099AspVal: 4.099 ± 0.068	0.633AspTrp: 0.633 ± 0.023	2.412AspTyr: 2.412 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	5.119GluAla: 5.119 ± 0.082	0.318GluCys: 0.318 ± 0.018	4.32GluAsp: 4.32 ± 0.074	7.643GluGlu: 7.643 ± 0.11	2.647GluPhe: 2.647 ± 0.051	4.289GluGly: 4.289 ± 0.072	1.563GluHis: 1.563 ± 0.034	6.101GluIle: 6.101 ± 0.073	6.62GluLys: 6.62 ± 0.083	7.353GluLeu: 7.353 ± 0.086	2.308GluMet: 2.308 ± 0.044	4.237GluAsn: 4.237 ± 0.065	2.066GluPro: 2.066 ± 0.046	3.48GluGln: 3.48 ± 0.065	3.275GluArg: 3.275 ± 0.061	3.995GluSer: 3.995 ± 0.062	3.882GluThr: 3.882 ± 0.055	5.482GluVal: 5.482 ± 0.092	0.88GluTrp: 0.88 ± 0.032	2.552GluTyr: 2.552 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	2.891PheAla: 2.891 ± 0.063	0.301PheCys: 0.301 ± 0.015	2.477PheAsp: 2.477 ± 0.049	2.848PheGlu: 2.848 ± 0.049	2.372PhePhe: 2.372 ± 0.061	3.2PheGly: 3.2 ± 0.059	1.056PheHis: 1.056 ± 0.03	4.127PheIle: 4.127 ± 0.074	2.297PheLys: 2.297 ± 0.051	4.45PheLeu: 4.45 ± 0.081	1.208PheMet: 1.208 ± 0.037	2.055PheAsn: 2.055 ± 0.04	1.708PhePro: 1.708 ± 0.04	1.62PheGln: 1.62 ± 0.04	1.514PheArg: 1.514 ± 0.04	3.248PheSer: 3.248 ± 0.052	2.66PheThr: 2.66 ± 0.052	3.086PheVal: 3.086 ± 0.051	0.501PheTrp: 0.501 ± 0.02	1.854PheTyr: 1.854 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	4.328GlyAla: 4.328 ± 0.079	0.523GlyCys: 0.523 ± 0.024	3.315GlyAsp: 3.315 ± 0.059	4.707GlyGlu: 4.707 ± 0.08	3.304GlyPhe: 3.304 ± 0.06	4.545GlyGly: 4.545 ± 0.085	1.468GlyHis: 1.468 ± 0.057	5.998GlyIle: 5.998 ± 0.086	4.667GlyLys: 4.667 ± 0.072	6.337GlyLeu: 6.337 ± 0.085	2.07GlyMet: 2.07 ± 0.036	3.071GlyAsn: 3.071 ± 0.059	1.666GlyPro: 1.666 ± 0.04	1.976GlyGln: 1.976 ± 0.044	2.384GlyArg: 2.384 ± 0.054	3.839GlySer: 3.839 ± 0.059	3.827GlyThr: 3.827 ± 0.06	4.931GlyVal: 4.931 ± 0.075	0.751GlyTrp: 0.751 ± 0.028	2.888GlyTyr: 2.888 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	1.313HisAla: 1.313 ± 0.035	0.17HisCys: 0.17 ± 0.011	1.164HisAsp: 1.164 ± 0.034	1.529HisGlu: 1.529 ± 0.043	1.057HisPhe: 1.057 ± 0.032	1.486HisGly: 1.486 ± 0.036	0.688HisHis: 0.688 ± 0.024	1.664HisIle: 1.664 ± 0.033	1.138HisLys: 1.138 ± 0.038	1.984HisLeu: 1.984 ± 0.047	0.56HisMet: 0.56 ± 0.024	0.89HisAsn: 0.89 ± 0.027	1.106HisPro: 1.106 ± 0.032	0.913HisGln: 0.913 ± 0.027	0.93HisArg: 0.93 ± 0.038	1.141HisSer: 1.141 ± 0.035	1.091HisThr: 1.091 ± 0.03	1.541HisVal: 1.541 ± 0.033	0.23HisTrp: 0.23 ± 0.017	0.873HisTyr: 0.873 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.88IleAla: 5.88 ± 0.09	0.605IleCys: 0.605 ± 0.027	4.814IleAsp: 4.814 ± 0.072	5.994IleGlu: 5.994 ± 0.079	3.57IlePhe: 3.57 ± 0.07	6.296IleGly: 6.296 ± 0.095	1.858IleHis: 1.858 ± 0.041	6.825IleIle: 6.825 ± 0.089	4.709IleLys: 4.709 ± 0.071	7.559IleLeu: 7.559 ± 0.109	1.911IleMet: 1.911 ± 0.04	3.796IleAsn: 3.796 ± 0.061	3.554IlePro: 3.554 ± 0.061	3.042IleGln: 3.042 ± 0.049	3.16IleArg: 3.16 ± 0.062	5.312IleSer: 5.312 ± 0.079	4.867IleThr: 4.867 ± 0.065	5.869IleVal: 5.869 ± 0.083	0.689IleTrp: 0.689 ± 0.028	2.709IleTyr: 2.709 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	4.12LysAla: 4.12 ± 0.065	0.277LysCys: 0.277 ± 0.016	3.919LysAsp: 3.919 ± 0.074	6.802LysGlu: 6.802 ± 0.084	1.925LysPhe: 1.925 ± 0.043	3.983LysGly: 3.983 ± 0.061	1.418LysHis: 1.418 ± 0.036	4.613LysIle: 4.613 ± 0.064	5.507LysLys: 5.507 ± 0.085	5.766LysLeu: 5.766 ± 0.071	1.994LysMet: 1.994 ± 0.042	3.505LysAsn: 3.505 ± 0.063	2.032LysPro: 2.032 ± 0.046	3.226LysGln: 3.226 ± 0.066	3.267LysArg: 3.267 ± 0.057	3.454LysSer: 3.454 ± 0.059	3.382LysThr: 3.382 ± 0.05	4.339LysVal: 4.339 ± 0.069	0.787LysTrp: 0.787 ± 0.027	2.21LysTyr: 2.21 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	6.503LeuAla: 6.503 ± 0.084	0.567LeuCys: 0.567 ± 0.024	5.114LeuAsp: 5.114 ± 0.069	6.946LeuGlu: 6.946 ± 0.083	4.86LeuPhe: 4.86 ± 0.078	6.193LeuGly: 6.193 ± 0.084	1.983LeuHis: 1.983 ± 0.043	7.614LeuIle: 7.614 ± 0.114	5.893LeuLys: 5.893 ± 0.068	9.748LeuLeu: 9.748 ± 0.123	2.412LeuMet: 2.412 ± 0.051	4.202LeuAsn: 4.202 ± 0.06	3.74LeuPro: 3.74 ± 0.051	3.587LeuGln: 3.587 ± 0.061	3.432LeuArg: 3.432 ± 0.06	6.391LeuSer: 6.391 ± 0.087	5.468LeuThr: 5.468 ± 0.063	6.457LeuVal: 6.457 ± 0.086	0.802LeuTrp: 0.802 ± 0.026	3.116LeuTyr: 3.116 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	1.737MetAla: 1.737 ± 0.041	0.109MetCys: 0.109 ± 0.01	1.661MetAsp: 1.661 ± 0.038	2.193MetGlu: 2.193 ± 0.048	1.128MetPhe: 1.128 ± 0.036	1.743MetGly: 1.743 ± 0.045	0.46MetHis: 0.46 ± 0.019	2.209MetIle: 2.209 ± 0.047	2.393MetLys: 2.393 ± 0.042	2.493MetLeu: 2.493 ± 0.048	0.765MetMet: 0.765 ± 0.025	1.64MetAsn: 1.64 ± 0.036	0.9MetPro: 0.9 ± 0.031	0.922MetGln: 0.922 ± 0.028	1.093MetArg: 1.093 ± 0.03	1.624MetSer: 1.624 ± 0.038	1.533MetThr: 1.533 ± 0.032	1.824MetVal: 1.824 ± 0.041	0.203MetTrp: 0.203 ± 0.012	0.835MetTyr: 0.835 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	2.622AsnAla: 2.622 ± 0.05	0.279AsnCys: 0.279 ± 0.017	2.753AsnAsp: 2.753 ± 0.055	3.991AsnGlu: 3.991 ± 0.068	1.843AsnPhe: 1.843 ± 0.039	3.399AsnGly: 3.399 ± 0.063	1.173AsnHis: 1.173 ± 0.031	3.806AsnIle: 3.806 ± 0.067	3.256AsnLys: 3.256 ± 0.055	4.051AsnLeu: 4.051 ± 0.051	1.386AsnMet: 1.386 ± 0.033	2.514AsnAsn: 2.514 ± 0.053	2.228AsnPro: 2.228 ± 0.048	2.146AsnGln: 2.146 ± 0.043	2.158AsnArg: 2.158 ± 0.043	2.561AsnSer: 2.561 ± 0.056	2.305AsnThr: 2.305 ± 0.047	3.211AsnVal: 3.211 ± 0.051	0.618AsnTrp: 0.618 ± 0.022	1.914AsnTyr: 1.914 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	1.966ProAla: 1.966 ± 0.052	0.188ProCys: 0.188 ± 0.014	2.006ProAsp: 2.006 ± 0.047	2.898ProGlu: 2.898 ± 0.058	1.891ProPhe: 1.891 ± 0.041	2.243ProGly: 2.243 ± 0.057	0.749ProHis: 0.749 ± 0.027	3.04ProIle: 3.04 ± 0.053	2.212ProLys: 2.212 ± 0.049	3.24ProLeu: 3.24 ± 0.058	0.827ProMet: 0.827 ± 0.031	1.956ProAsn: 1.956 ± 0.043	0.934ProPro: 0.934 ± 0.033	1.021ProGln: 1.021 ± 0.03	1.076ProArg: 1.076 ± 0.031	2.306ProSer: 2.306 ± 0.042	2.159ProThr: 2.159 ± 0.046	2.709ProVal: 2.709 ± 0.057	0.371ProTrp: 0.371 ± 0.019	1.409ProTyr: 1.409 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.622GlnAla: 2.622 ± 0.048	0.172GlnCys: 0.172 ± 0.013	1.896GlnAsp: 1.896 ± 0.037	3.131GlnGlu: 3.131 ± 0.063	1.537GlnPhe: 1.537 ± 0.036	2.178GlnGly: 2.178 ± 0.047	0.818GlnHis: 0.818 ± 0.032	2.691GlnIle: 2.691 ± 0.049	2.569GlnLys: 2.569 ± 0.052	4.022GlnLeu: 4.022 ± 0.069	1.145GlnMet: 1.145 ± 0.031	1.624GlnAsn: 1.624 ± 0.039	1.191GlnPro: 1.191 ± 0.036	1.904GlnGln: 1.904 ± 0.068	1.404GlnArg: 1.404 ± 0.042	2.197GlnSer: 2.197 ± 0.047	2.051GlnThr: 2.051 ± 0.044	2.539GlnVal: 2.539 ± 0.051	0.403GlnTrp: 0.403 ± 0.018	1.282GlnTyr: 1.282 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.192ArgAla: 2.192 ± 0.042	0.235ArgCys: 0.235 ± 0.013	2.121ArgAsp: 2.121 ± 0.044	3.142ArgGlu: 3.142 ± 0.055	1.812ArgPhe: 1.812 ± 0.038	2.236ArgGly: 2.236 ± 0.058	0.755ArgHis: 0.755 ± 0.023	3.102ArgIle: 3.102 ± 0.055	3.143ArgLys: 3.143 ± 0.061	3.731ArgLeu: 3.731 ± 0.06	1.227ArgMet: 1.227 ± 0.033	2.088ArgAsn: 2.088 ± 0.049	1.136ArgPro: 1.136 ± 0.031	1.31ArgGln: 1.31 ± 0.035	1.668ArgArg: 1.668 ± 0.045	2.23ArgSer: 2.23 ± 0.045	1.975ArgThr: 1.975 ± 0.052	2.565ArgVal: 2.565 ± 0.047	0.403ArgTrp: 0.403 ± 0.022	1.577ArgTyr: 1.577 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	3.248SerAla: 3.248 ± 0.06	0.358SerCys: 0.358 ± 0.016	3.241SerAsp: 3.241 ± 0.071	4.128SerGlu: 4.128 ± 0.064	3.294SerPhe: 3.294 ± 0.066	4.283SerGly: 4.283 ± 0.07	1.151SerHis: 1.151 ± 0.035	5.501SerIle: 5.501 ± 0.082	3.78SerLys: 3.78 ± 0.063	5.924SerLeu: 5.924 ± 0.079	1.656SerMet: 1.656 ± 0.038	2.956SerAsn: 2.956 ± 0.05	1.998SerPro: 1.998 ± 0.045	1.876SerGln: 1.876 ± 0.043	2.165SerArg: 2.165 ± 0.042	3.965SerSer: 3.965 ± 0.073	3.196SerThr: 3.196 ± 0.055	4.093SerVal: 4.093 ± 0.064	0.66SerTrp: 0.66 ± 0.025	2.465SerTyr: 2.465 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	3.419ThrAla: 3.419 ± 0.06	0.357ThrCys: 0.357 ± 0.017	2.942ThrAsp: 2.942 ± 0.054	3.707ThrGlu: 3.707 ± 0.059	2.653ThrPhe: 2.653 ± 0.057	4.002ThrGly: 4.002 ± 0.07	1.032ThrHis: 1.032 ± 0.03	5.214ThrIle: 5.214 ± 0.068	3.335ThrLys: 3.335 ± 0.052	5.074ThrLeu: 5.074 ± 0.065	1.341ThrMet: 1.341 ± 0.031	2.793ThrAsn: 2.793 ± 0.058	2.133ThrPro: 2.133 ± 0.044	1.458ThrGln: 1.458 ± 0.041	1.842ThrArg: 1.842 ± 0.046	3.35ThrSer: 3.35 ± 0.055	3.233ThrThr: 3.233 ± 0.065	4.15ThrVal: 4.15 ± 0.074	0.579ThrTrp: 0.579 ± 0.022	2.201ThrTyr: 2.201 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	4.659ValAla: 4.659 ± 0.073	0.507ValCys: 0.507 ± 0.021	3.948ValAsp: 3.948 ± 0.054	5.305ValGlu: 5.305 ± 0.09	3.219ValPhe: 3.219 ± 0.065	4.731ValGly: 4.731 ± 0.068	1.396ValHis: 1.396 ± 0.036	5.932ValIle: 5.932 ± 0.07	4.334ValLys: 4.334 ± 0.074	6.716ValLeu: 6.716 ± 0.088	1.931ValMet: 1.931 ± 0.043	3.322ValAsn: 3.322 ± 0.058	2.634ValPro: 2.634 ± 0.05	2.352ValGln: 2.352 ± 0.042	2.51ValArg: 2.51 ± 0.05	4.548ValSer: 4.548 ± 0.072	4.194ValThr: 4.194 ± 0.07	5.096ValVal: 5.096 ± 0.081	0.622ValTrp: 0.622 ± 0.024	2.317ValTyr: 2.317 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	0.578TrpAla: 0.578 ± 0.027	0.071TrpCys: 0.071 ± 0.008	0.586TrpAsp: 0.586 ± 0.023	0.751TrpGlu: 0.751 ± 0.031	0.551TrpPhe: 0.551 ± 0.024	0.701TrpGly: 0.701 ± 0.025	0.199TrpHis: 0.199 ± 0.014	0.888TrpIle: 0.888 ± 0.029	0.758TrpLys: 0.758 ± 0.029	1.131TrpLeu: 1.131 ± 0.032	0.325TrpMet: 0.325 ± 0.02	0.58TrpAsn: 0.58 ± 0.023	0.252TrpPro: 0.252 ± 0.016	0.358TrpGln: 0.358 ± 0.018	0.349TrpArg: 0.349 ± 0.017	0.602TrpSer: 0.602 ± 0.022	0.498TrpThr: 0.498 ± 0.021	0.688TrpVal: 0.688 ± 0.025	0.162TrpTrp: 0.162 ± 0.012	0.405TrpTyr: 0.405 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.061TyrAla: 2.061 ± 0.043	0.283TyrCys: 0.283 ± 0.013	2.177TyrAsp: 2.177 ± 0.08	2.799TyrGlu: 2.799 ± 0.05	1.951TyrPhe: 1.951 ± 0.045	2.536TyrGly: 2.536 ± 0.048	1.032TyrHis: 1.032 ± 0.033	2.762TyrIle: 2.762 ± 0.048	2.095TyrLys: 2.095 ± 0.048	3.498TyrLeu: 3.498 ± 0.065	0.903TyrMet: 0.903 ± 0.025	1.651TyrAsn: 1.651 ± 0.046	1.467TyrPro: 1.467 ± 0.041	1.703TyrGln: 1.703 ± 0.039	1.642TyrArg: 1.642 ± 0.042	2.133TyrSer: 2.133 ± 0.048	1.924TyrThr: 1.924 ± 0.042	2.479TyrVal: 2.479 ± 0.04	0.454TyrTrp: 0.454 ± 0.019	1.611TyrTyr: 1.611 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4042 proteins (1157730 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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