Amino acid dipepetide frequency for Hubei toti-like virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.971AlaAla: 2.971 ± 0.705
0.0AlaCys: 0.0 ± 0.0
3.565AlaAsp: 3.565 ± 1.038
1.188AlaGlu: 1.188 ± 0.666
2.377AlaPhe: 2.377 ± 0.589
2.971AlaGly: 2.971 ± 1.665
1.188AlaHis: 1.188 ± 0.666
2.377AlaIle: 2.377 ± 0.372
1.783AlaLys: 1.783 ± 0.039
5.348AlaLeu: 5.348 ± 1.806
2.971AlaMet: 2.971 ± 1.511
2.971AlaAsn: 2.971 ± 0.705
2.377AlaPro: 2.377 ± 0.372
0.594AlaGln: 0.594 ± 0.333
2.377AlaArg: 2.377 ± 0.372
3.565AlaSer: 3.565 ± 0.884
8.318AlaThr: 8.318 ± 2.742
4.159AlaVal: 4.159 ± 2.332
1.188AlaTrp: 1.188 ± 0.295
6.536AlaTyr: 6.536 ± 0.179
0.0AlaXaa: 0.0 ± 0.0
Cys
0.594CysAla: 0.594 ± 0.333
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.594CysGly: 0.594 ± 0.333
1.188CysHis: 1.188 ± 0.295
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.594CysMet: 0.594 ± 0.628
0.594CysAsn: 0.594 ± 0.333
0.0CysPro: 0.0 ± 0.0
0.594CysGln: 0.594 ± 0.333
0.594CysArg: 0.594 ± 0.333
1.188CysSer: 1.188 ± 1.255
0.0CysThr: 0.0 ± 0.0
0.594CysVal: 0.594 ± 0.628
0.594CysTrp: 0.594 ± 0.333
0.594CysTyr: 0.594 ± 0.333
0.0CysXaa: 0.0 ± 0.0
Asp
6.536AspAla: 6.536 ± 2.703
0.594AspCys: 0.594 ± 0.333
4.753AspAsp: 4.753 ± 0.217
2.377AspGlu: 2.377 ± 0.589
1.188AspPhe: 1.188 ± 0.295
3.565AspGly: 3.565 ± 0.077
1.188AspHis: 1.188 ± 0.295
5.942AspIle: 5.942 ± 0.512
6.536AspLys: 6.536 ± 0.782
4.159AspLeu: 4.159 ± 0.41
0.594AspMet: 0.594 ± 0.628
1.188AspAsn: 1.188 ± 0.295
3.565AspPro: 3.565 ± 1.999
2.377AspGln: 2.377 ± 0.372
4.159AspArg: 4.159 ± 0.551
7.13AspSer: 7.13 ± 2.076
1.783AspThr: 1.783 ± 0.039
1.783AspVal: 1.783 ± 0.922
1.783AspTrp: 1.783 ± 0.999
1.188AspTyr: 1.188 ± 0.295
0.0AspXaa: 0.0 ± 0.0
Glu
2.377GluAla: 2.377 ± 0.372
0.0GluCys: 0.0 ± 0.0
1.188GluAsp: 1.188 ± 0.666
0.594GluGlu: 0.594 ± 0.628
2.377GluPhe: 2.377 ± 1.55
2.971GluGly: 2.971 ± 0.256
0.0GluHis: 0.0 ± 0.0
3.565GluIle: 3.565 ± 2.805
0.594GluLys: 0.594 ± 0.628
2.377GluLeu: 2.377 ± 0.589
0.594GluMet: 0.594 ± 0.333
0.594GluAsn: 0.594 ± 0.628
0.594GluPro: 0.594 ± 0.628
2.377GluGln: 2.377 ± 1.55
1.783GluArg: 1.783 ± 0.922
1.783GluSer: 1.783 ± 0.039
3.565GluThr: 3.565 ± 0.077
1.188GluVal: 1.188 ± 0.666
1.783GluTrp: 1.783 ± 0.039
2.971GluTyr: 2.971 ± 0.705
0.0GluXaa: 0.0 ± 0.0
Phe
0.594PheAla: 0.594 ± 0.333
1.188PheCys: 1.188 ± 0.295
4.159PheAsp: 4.159 ± 0.41
1.188PheGlu: 1.188 ± 0.295
1.783PhePhe: 1.783 ± 0.039
2.377PheGly: 2.377 ± 0.589
0.0PheHis: 0.0 ± 0.0
0.594PheIle: 0.594 ± 0.333
1.783PheLys: 1.783 ± 0.039
7.724PheLeu: 7.724 ± 0.487
1.783PheMet: 1.783 ± 0.039
1.188PheAsn: 1.188 ± 1.255
1.783PhePro: 1.783 ± 0.922
1.783PheGln: 1.783 ± 0.039
1.783PheArg: 1.783 ± 0.999
5.348PheSer: 5.348 ± 0.845
1.188PheThr: 1.188 ± 1.255
2.377PheVal: 2.377 ± 0.589
2.377PheTrp: 2.377 ± 1.332
1.783PheTyr: 1.783 ± 0.922
0.0PheXaa: 0.0 ± 0.0
Gly
2.971GlyAla: 2.971 ± 0.705
0.0GlyCys: 0.0 ± 0.0
3.565GlyAsp: 3.565 ± 1.844
3.565GlyGlu: 3.565 ± 1.844
1.783GlyPhe: 1.783 ± 0.039
7.13GlyGly: 7.13 ± 2.728
0.0GlyHis: 0.0 ± 0.0
4.753GlyIle: 4.753 ± 2.139
3.565GlyLys: 3.565 ± 1.038
4.753GlyLeu: 4.753 ± 0.217
1.188GlyMet: 1.188 ± 0.295
2.971GlyAsn: 2.971 ± 1.665
2.971GlyPro: 2.971 ± 1.217
2.971GlyGln: 2.971 ± 0.256
2.971GlyArg: 2.971 ± 0.256
1.783GlySer: 1.783 ± 0.999
1.783GlyThr: 1.783 ± 0.039
1.783GlyVal: 1.783 ± 0.999
0.594GlyTrp: 0.594 ± 0.628
2.971GlyTyr: 2.971 ± 0.705
0.0GlyXaa: 0.0 ± 0.0
His
0.594HisAla: 0.594 ± 0.333
0.0HisCys: 0.0 ± 0.0
1.783HisAsp: 1.783 ± 0.922
0.0HisGlu: 0.0 ± 0.0
1.188HisPhe: 1.188 ± 0.666
0.594HisGly: 0.594 ± 0.628
0.0HisHis: 0.0 ± 0.0
2.377HisIle: 2.377 ± 1.55
0.594HisLys: 0.594 ± 0.333
2.971HisLeu: 2.971 ± 1.217
0.594HisMet: 0.594 ± 0.628
1.188HisAsn: 1.188 ± 0.295
1.783HisPro: 1.783 ± 0.999
1.188HisGln: 1.188 ± 0.295
0.594HisArg: 0.594 ± 0.628
3.565HisSer: 3.565 ± 1.038
0.594HisThr: 0.594 ± 0.628
1.783HisVal: 1.783 ± 0.039
0.594HisTrp: 0.594 ± 0.333
0.594HisTyr: 0.594 ± 0.628
0.0HisXaa: 0.0 ± 0.0
Ile
4.159IleAla: 4.159 ± 0.551
0.0IleCys: 0.0 ± 0.0
5.942IleAsp: 5.942 ± 0.449
1.188IleGlu: 1.188 ± 0.295
1.783IlePhe: 1.783 ± 0.039
2.377IleGly: 2.377 ± 0.589
1.188IleHis: 1.188 ± 1.255
5.348IleIle: 5.348 ± 3.727
2.377IleLys: 2.377 ± 0.372
2.971IleLeu: 2.971 ± 2.178
1.783IleMet: 1.783 ± 0.922
2.377IleAsn: 2.377 ± 0.589
7.13IlePro: 7.13 ± 2.076
0.594IleGln: 0.594 ± 0.333
2.377IleArg: 2.377 ± 0.372
6.536IleSer: 6.536 ± 3.061
3.565IleThr: 3.565 ± 1.038
2.377IleVal: 2.377 ± 0.372
1.783IleTrp: 1.783 ± 0.039
1.783IleTyr: 1.783 ± 0.039
0.0IleXaa: 0.0 ± 0.0
Lys
1.188LysAla: 1.188 ± 0.666
0.0LysCys: 0.0 ± 0.0
4.753LysAsp: 4.753 ± 1.704
2.377LysGlu: 2.377 ± 0.372
1.783LysPhe: 1.783 ± 0.999
0.594LysGly: 0.594 ± 0.628
1.188LysHis: 1.188 ± 0.666
4.159LysIle: 4.159 ± 1.511
4.753LysLys: 4.753 ± 0.743
5.348LysLeu: 5.348 ± 1.076
0.594LysMet: 0.594 ± 0.333
1.783LysAsn: 1.783 ± 0.999
1.188LysPro: 1.188 ± 1.255
4.753LysGln: 4.753 ± 0.217
1.783LysArg: 1.783 ± 1.883
5.348LysSer: 5.348 ± 1.806
4.159LysThr: 4.159 ± 0.551
3.565LysVal: 3.565 ± 0.077
2.971LysTrp: 2.971 ± 1.217
3.565LysTyr: 3.565 ± 1.038
0.0LysXaa: 0.0 ± 0.0
Leu
4.753LeuAla: 4.753 ± 0.743
1.188LeuCys: 1.188 ± 0.666
4.159LeuAsp: 4.159 ± 1.371
5.348LeuGlu: 5.348 ± 4.688
2.377LeuPhe: 2.377 ± 0.589
8.318LeuGly: 8.318 ± 2.062
2.971LeuHis: 2.971 ± 1.217
3.565LeuIle: 3.565 ± 1.038
4.753LeuLys: 4.753 ± 0.743
7.13LeuLeu: 7.13 ± 0.807
0.0LeuMet: 0.0 ± 0.0
2.377LeuAsn: 2.377 ± 1.55
5.348LeuPro: 5.348 ± 1.076
2.377LeuGln: 2.377 ± 0.372
1.783LeuArg: 1.783 ± 1.883
7.724LeuSer: 7.724 ± 1.434
7.724LeuThr: 7.724 ± 1.448
5.348LeuVal: 5.348 ± 0.845
0.594LeuTrp: 0.594 ± 0.628
2.971LeuTyr: 2.971 ± 0.705
0.0LeuXaa: 0.0 ± 0.0
Met
1.188MetAla: 1.188 ± 0.295
1.783MetCys: 1.783 ± 0.922
1.188MetAsp: 1.188 ± 0.666
0.594MetGlu: 0.594 ± 0.628
0.594MetPhe: 0.594 ± 0.333
2.377MetGly: 2.377 ± 0.372
0.0MetHis: 0.0 ± 0.0
1.783MetIle: 1.783 ± 0.999
0.594MetLys: 0.594 ± 0.333
2.971MetLeu: 2.971 ± 0.256
0.594MetMet: 0.594 ± 0.333
1.188MetAsn: 1.188 ± 1.255
1.188MetPro: 1.188 ± 0.666
0.594MetGln: 0.594 ± 0.333
0.594MetArg: 0.594 ± 0.628
2.971MetSer: 2.971 ± 0.256
1.188MetThr: 1.188 ± 0.666
0.594MetVal: 0.594 ± 0.333
0.594MetTrp: 0.594 ± 0.333
1.188MetTyr: 1.188 ± 0.295
0.0MetXaa: 0.0 ± 0.0
Asn
4.159AsnAla: 4.159 ± 0.41
0.594AsnCys: 0.594 ± 0.333
1.783AsnAsp: 1.783 ± 0.999
1.188AsnGlu: 1.188 ± 0.295
1.188AsnPhe: 1.188 ± 0.666
1.783AsnGly: 1.783 ± 0.039
0.594AsnHis: 0.594 ± 0.628
2.971AsnIle: 2.971 ± 0.256
4.159AsnLys: 4.159 ± 1.511
4.159AsnLeu: 4.159 ± 2.332
1.188AsnMet: 1.188 ± 0.666
2.377AsnAsn: 2.377 ± 0.589
0.594AsnPro: 0.594 ± 0.333
2.971AsnGln: 2.971 ± 0.705
2.377AsnArg: 2.377 ± 0.372
4.753AsnSer: 4.753 ± 0.217
4.753AsnThr: 4.753 ± 0.743
3.565AsnVal: 3.565 ± 0.077
1.188AsnTrp: 1.188 ± 1.255
1.188AsnTyr: 1.188 ± 0.666
0.0AsnXaa: 0.0 ± 0.0
Pro
6.536ProAla: 6.536 ± 1.14
0.0ProCys: 0.0 ± 0.0
5.348ProAsp: 5.348 ± 1.076
1.188ProGlu: 1.188 ± 0.666
2.377ProPhe: 2.377 ± 1.332
1.188ProGly: 1.188 ± 0.666
2.377ProHis: 2.377 ± 0.372
2.377ProIle: 2.377 ± 1.332
2.377ProLys: 2.377 ± 0.589
1.188ProLeu: 1.188 ± 0.666
1.188ProMet: 1.188 ± 1.255
4.753ProAsn: 4.753 ± 0.743
4.159ProPro: 4.159 ± 2.332
1.783ProGln: 1.783 ± 0.039
2.377ProArg: 2.377 ± 0.372
8.913ProSer: 8.913 ± 1.153
3.565ProThr: 3.565 ± 1.038
5.942ProVal: 5.942 ± 2.37
1.188ProTrp: 1.188 ± 0.295
1.783ProTyr: 1.783 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
2.971GlnAla: 2.971 ± 1.665
0.594GlnCys: 0.594 ± 0.628
0.594GlnAsp: 0.594 ± 0.628
0.594GlnGlu: 0.594 ± 0.333
3.565GlnPhe: 3.565 ± 0.884
1.783GlnGly: 1.783 ± 0.039
2.971GlnHis: 2.971 ± 1.217
1.783GlnIle: 1.783 ± 0.039
2.377GlnLys: 2.377 ± 0.372
3.565GlnLeu: 3.565 ± 0.077
0.594GlnMet: 0.594 ± 0.333
2.377GlnAsn: 2.377 ± 1.332
2.971GlnPro: 2.971 ± 1.665
2.971GlnGln: 2.971 ± 0.705
1.188GlnArg: 1.188 ± 0.295
7.724GlnSer: 7.724 ± 0.474
1.188GlnThr: 1.188 ± 0.295
2.377GlnVal: 2.377 ± 0.372
0.594GlnTrp: 0.594 ± 0.333
1.783GlnTyr: 1.783 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
1.188ArgAla: 1.188 ± 0.666
0.0ArgCys: 0.0 ± 0.0
1.188ArgAsp: 1.188 ± 0.666
2.377ArgGlu: 2.377 ± 1.55
2.971ArgPhe: 2.971 ± 1.217
0.594ArgGly: 0.594 ± 0.628
0.594ArgHis: 0.594 ± 0.333
2.377ArgIle: 2.377 ± 0.372
2.971ArgLys: 2.971 ± 0.256
2.971ArgLeu: 2.971 ± 2.178
2.377ArgMet: 2.377 ± 0.589
2.377ArgAsn: 2.377 ± 0.589
1.783ArgPro: 1.783 ± 0.039
1.188ArgGln: 1.188 ± 0.295
2.377ArgArg: 2.377 ± 0.589
4.159ArgSer: 4.159 ± 0.41
5.348ArgThr: 5.348 ± 0.845
0.594ArgVal: 0.594 ± 0.628
3.565ArgTrp: 3.565 ± 0.884
0.594ArgTyr: 0.594 ± 0.628
0.0ArgXaa: 0.0 ± 0.0
Ser
4.159SerAla: 4.159 ± 1.371
0.594SerCys: 0.594 ± 0.333
7.13SerAsp: 7.13 ± 0.154
2.971SerGlu: 2.971 ± 0.256
4.753SerPhe: 4.753 ± 0.217
4.753SerGly: 4.753 ± 1.178
3.565SerHis: 3.565 ± 2.805
5.348SerIle: 5.348 ± 1.806
4.753SerLys: 4.753 ± 1.178
7.13SerLeu: 7.13 ± 0.807
2.377SerMet: 2.377 ± 1.332
5.348SerAsn: 5.348 ± 1.076
5.942SerPro: 5.942 ± 0.512
4.159SerGln: 4.159 ± 0.41
4.159SerArg: 4.159 ± 1.511
10.695SerSer: 10.695 ± 4.074
9.507SerThr: 9.507 ± 1.486
6.536SerVal: 6.536 ± 0.179
1.188SerTrp: 1.188 ± 1.255
5.348SerTyr: 5.348 ± 0.116
0.0SerXaa: 0.0 ± 0.0
Thr
3.565ThrAla: 3.565 ± 1.038
0.594ThrCys: 0.594 ± 0.333
4.753ThrAsp: 4.753 ± 0.743
4.159ThrGlu: 4.159 ± 1.371
3.565ThrPhe: 3.565 ± 0.884
3.565ThrGly: 3.565 ± 0.077
1.188ThrHis: 1.188 ± 0.666
2.971ThrIle: 2.971 ± 0.705
4.753ThrLys: 4.753 ± 1.178
5.348ThrLeu: 5.348 ± 0.845
0.0ThrMet: 0.0 ± 0.0
4.159ThrAsn: 4.159 ± 0.41
7.724ThrPro: 7.724 ± 2.409
3.565ThrGln: 3.565 ± 1.038
2.971ThrArg: 2.971 ± 0.705
5.942ThrSer: 5.942 ± 1.473
5.942ThrThr: 5.942 ± 1.409
5.942ThrVal: 5.942 ± 0.449
2.377ThrTrp: 2.377 ± 0.372
2.377ThrTyr: 2.377 ± 1.332
0.0ThrXaa: 0.0 ± 0.0
Val
2.971ValAla: 2.971 ± 0.256
0.0ValCys: 0.0 ± 0.0
4.159ValAsp: 4.159 ± 1.511
1.188ValGlu: 1.188 ± 0.666
1.783ValPhe: 1.783 ± 0.039
2.377ValGly: 2.377 ± 0.589
1.188ValHis: 1.188 ± 0.666
2.971ValIle: 2.971 ± 0.705
4.159ValLys: 4.159 ± 1.371
4.159ValLeu: 4.159 ± 0.551
0.594ValMet: 0.594 ± 0.333
1.783ValAsn: 1.783 ± 0.039
4.753ValPro: 4.753 ± 0.743
4.753ValGln: 4.753 ± 0.743
2.377ValArg: 2.377 ± 1.55
5.942ValSer: 5.942 ± 0.449
5.942ValThr: 5.942 ± 2.37
3.565ValVal: 3.565 ± 0.077
0.594ValTrp: 0.594 ± 0.333
2.377ValTyr: 2.377 ± 0.589
0.0ValXaa: 0.0 ± 0.0
Trp
2.971TrpAla: 2.971 ± 0.256
0.0TrpCys: 0.0 ± 0.0
1.188TrpAsp: 1.188 ± 0.295
0.594TrpGlu: 0.594 ± 0.628
2.377TrpPhe: 2.377 ± 0.589
1.188TrpGly: 1.188 ± 0.295
0.0TrpHis: 0.0 ± 0.0
1.188TrpIle: 1.188 ± 0.295
0.0TrpLys: 0.0 ± 0.0
2.971TrpLeu: 2.971 ± 0.256
1.783TrpMet: 1.783 ± 0.716
1.783TrpAsn: 1.783 ± 0.999
1.188TrpPro: 1.188 ± 0.666
1.188TrpGln: 1.188 ± 0.295
1.188TrpArg: 1.188 ± 0.295
0.594TrpSer: 0.594 ± 0.333
2.971TrpThr: 2.971 ± 0.256
2.971TrpVal: 2.971 ± 0.256
0.594TrpTrp: 0.594 ± 0.628
0.594TrpTyr: 0.594 ± 0.628
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.377TyrAla: 2.377 ± 0.372
0.594TyrCys: 0.594 ± 0.628
1.188TyrAsp: 1.188 ± 0.666
0.594TyrGlu: 0.594 ± 0.333
2.971TyrPhe: 2.971 ± 0.256
2.971TyrGly: 2.971 ± 1.665
1.188TyrHis: 1.188 ± 0.666
1.188TyrIle: 1.188 ± 0.666
2.971TyrLys: 2.971 ± 1.217
3.565TyrLeu: 3.565 ± 0.884
1.783TyrMet: 1.783 ± 0.039
4.159TyrAsn: 4.159 ± 2.332
3.565TyrPro: 3.565 ± 0.077
1.783TyrGln: 1.783 ± 0.039
1.783TyrArg: 1.783 ± 0.922
4.753TyrSer: 4.753 ± 0.217
2.377TyrThr: 2.377 ± 0.589
0.594TyrVal: 0.594 ± 0.628
1.783TyrTrp: 1.783 ± 0.039
2.971TyrTyr: 2.971 ± 0.705
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1684 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski