Amino acid dipepetide frequency for Listeria phage A511 (Bacteriophage A511)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.751AlaAla: 0.751 ± 0.329
0.25AlaCys: 0.25 ± 0.078
3.279AlaAsp: 3.279 ± 0.296
4.58AlaGlu: 4.58 ± 0.444
2.002AlaPhe: 2.002 ± 0.215
3.829AlaGly: 3.829 ± 0.434
0.926AlaHis: 0.926 ± 0.128
4.205AlaIle: 4.205 ± 0.357
4.73AlaLys: 4.73 ± 0.383
5.531AlaLeu: 5.531 ± 0.341
1.577AlaMet: 1.577 ± 0.269
3.679AlaAsn: 3.679 ± 0.323
1.727AlaPro: 1.727 ± 0.29
2.127AlaGln: 2.127 ± 0.267
2.628AlaArg: 2.628 ± 0.282
4.48AlaSer: 4.48 ± 0.377
3.754AlaThr: 3.754 ± 0.315
3.93AlaVal: 3.93 ± 0.268
0.325AlaTrp: 0.325 ± 0.094
2.903AlaTyr: 2.903 ± 0.334
0.0AlaXaa: 0.0 ± 0.0
Cys
0.225CysAla: 0.225 ± 0.08
0.15CysCys: 0.15 ± 0.056
0.35CysAsp: 0.35 ± 0.087
0.325CysGlu: 0.325 ± 0.111
0.35CysPhe: 0.35 ± 0.085
0.451CysGly: 0.451 ± 0.098
0.175CysHis: 0.175 ± 0.062
0.35CysIle: 0.35 ± 0.097
0.626CysLys: 0.626 ± 0.114
0.551CysLeu: 0.551 ± 0.102
0.1CysMet: 0.1 ± 0.05
0.4CysAsn: 0.4 ± 0.101
0.325CysPro: 0.325 ± 0.122
0.225CysGln: 0.225 ± 0.068
0.275CysArg: 0.275 ± 0.085
0.501CysSer: 0.501 ± 0.124
0.3CysThr: 0.3 ± 0.102
0.526CysVal: 0.526 ± 0.123
0.025CysTrp: 0.025 ± 0.025
0.501CysTyr: 0.501 ± 0.122
0.0CysXaa: 0.0 ± 0.0
Asp
2.278AspAla: 2.278 ± 0.303
0.501AspCys: 0.501 ± 0.122
2.653AspAsp: 2.653 ± 0.255
4.005AspGlu: 4.005 ± 0.372
2.853AspPhe: 2.853 ± 0.222
3.204AspGly: 3.204 ± 0.317
0.501AspHis: 0.501 ± 0.133
4.505AspIle: 4.505 ± 0.361
5.757AspLys: 5.757 ± 0.425
5.481AspLeu: 5.481 ± 0.305
1.627AspMet: 1.627 ± 0.194
4.205AspAsn: 4.205 ± 0.332
1.477AspPro: 1.477 ± 0.205
1.327AspGln: 1.327 ± 0.266
2.603AspArg: 2.603 ± 0.289
4.305AspSer: 4.305 ± 0.317
3.604AspThr: 3.604 ± 0.293
3.754AspVal: 3.754 ± 0.335
0.726AspTrp: 0.726 ± 0.135
3.554AspTyr: 3.554 ± 0.32
0.0AspXaa: 0.0 ± 0.0
Glu
5.631GluAla: 5.631 ± 0.424
0.476GluCys: 0.476 ± 0.119
5.256GluAsp: 5.256 ± 0.42
8.81GluGlu: 8.81 ± 0.841
2.928GluPhe: 2.928 ± 0.234
4.305GluGly: 4.305 ± 0.376
1.051GluHis: 1.051 ± 0.212
4.505GluIle: 4.505 ± 0.336
7.859GluLys: 7.859 ± 0.586
7.784GluLeu: 7.784 ± 0.55
1.852GluMet: 1.852 ± 0.218
4.405GluAsn: 4.405 ± 0.324
1.802GluPro: 1.802 ± 0.259
2.853GluGln: 2.853 ± 0.277
3.579GluArg: 3.579 ± 0.291
4.63GluSer: 4.63 ± 0.343
4.105GluThr: 4.105 ± 0.348
6.132GluVal: 6.132 ± 0.466
0.701GluTrp: 0.701 ± 0.141
3.079GluTyr: 3.079 ± 0.282
0.0GluXaa: 0.0 ± 0.0
Phe
1.752PheAla: 1.752 ± 0.234
0.275PheCys: 0.275 ± 0.094
2.178PheAsp: 2.178 ± 0.243
2.603PheGlu: 2.603 ± 0.261
1.702PhePhe: 1.702 ± 0.2
2.328PheGly: 2.328 ± 0.241
0.601PheHis: 0.601 ± 0.13
2.953PheIle: 2.953 ± 0.319
2.653PheLys: 2.653 ± 0.249
4.13PheLeu: 4.13 ± 0.393
1.001PheMet: 1.001 ± 0.147
2.353PheAsn: 2.353 ± 0.283
1.076PhePro: 1.076 ± 0.175
1.101PheGln: 1.101 ± 0.155
1.352PheArg: 1.352 ± 0.173
3.254PheSer: 3.254 ± 0.293
2.553PheThr: 2.553 ± 0.223
3.379PheVal: 3.379 ± 0.29
0.225PheTrp: 0.225 ± 0.071
2.328PheTyr: 2.328 ± 0.256
0.0PheXaa: 0.0 ± 0.0
Gly
3.779GlyAla: 3.779 ± 0.687
0.526GlyCys: 0.526 ± 0.13
3.804GlyAsp: 3.804 ± 0.399
4.105GlyGlu: 4.105 ± 0.355
2.127GlyPhe: 2.127 ± 0.218
4.705GlyGly: 4.705 ± 0.808
0.801GlyHis: 0.801 ± 0.182
4.18GlyIle: 4.18 ± 0.357
5.256GlyLys: 5.256 ± 0.477
4.205GlyLeu: 4.205 ± 0.382
1.602GlyMet: 1.602 ± 0.227
3.629GlyAsn: 3.629 ± 0.243
0.025GlyPro: 0.025 ± 0.024
1.477GlyGln: 1.477 ± 0.252
2.152GlyArg: 2.152 ± 0.227
4.305GlySer: 4.305 ± 0.451
3.879GlyThr: 3.879 ± 0.324
4.806GlyVal: 4.806 ± 0.337
0.676GlyTrp: 0.676 ± 0.14
2.853GlyTyr: 2.853 ± 0.231
0.0GlyXaa: 0.0 ± 0.0
His
0.751HisAla: 0.751 ± 0.134
0.225HisCys: 0.225 ± 0.071
0.876HisAsp: 0.876 ± 0.182
0.901HisGlu: 0.901 ± 0.142
0.526HisPhe: 0.526 ± 0.117
0.851HisGly: 0.851 ± 0.144
0.275HisHis: 0.275 ± 0.088
1.226HisIle: 1.226 ± 0.242
1.301HisLys: 1.301 ± 0.186
1.327HisLeu: 1.327 ± 0.177
0.275HisMet: 0.275 ± 0.096
0.651HisAsn: 0.651 ± 0.121
0.425HisPro: 0.425 ± 0.108
0.375HisGln: 0.375 ± 0.084
0.651HisArg: 0.651 ± 0.136
0.976HisSer: 0.976 ± 0.187
1.026HisThr: 1.026 ± 0.179
1.076HisVal: 1.076 ± 0.204
0.3HisTrp: 0.3 ± 0.112
0.951HisTyr: 0.951 ± 0.17
0.0HisXaa: 0.0 ± 0.0
Ile
4.33IleAla: 4.33 ± 0.378
0.375IleCys: 0.375 ± 0.111
4.005IleAsp: 4.005 ± 0.32
5.657IleGlu: 5.657 ± 0.451
1.927IlePhe: 1.927 ± 0.233
3.804IleGly: 3.804 ± 0.391
1.051IleHis: 1.051 ± 0.178
4.931IleIle: 4.931 ± 0.359
5.381IleLys: 5.381 ± 0.375
5.331IleLeu: 5.331 ± 0.419
1.902IleMet: 1.902 ± 0.222
3.554IleAsn: 3.554 ± 0.344
2.503IlePro: 2.503 ± 0.246
2.228IleGln: 2.228 ± 0.208
3.079IleArg: 3.079 ± 0.279
4.355IleSer: 4.355 ± 0.37
4.005IleThr: 4.005 ± 0.309
4.68IleVal: 4.68 ± 0.349
0.551IleTrp: 0.551 ± 0.142
2.328IleTyr: 2.328 ± 0.227
0.0IleXaa: 0.0 ± 0.0
Lys
4.906LysAla: 4.906 ± 0.373
0.375LysCys: 0.375 ± 0.118
5.456LysAsp: 5.456 ± 0.403
9.686LysGlu: 9.686 ± 0.624
2.978LysPhe: 2.978 ± 0.277
5.256LysGly: 5.256 ± 0.378
1.402LysHis: 1.402 ± 0.204
4.956LysIle: 4.956 ± 0.412
8.835LysLys: 8.835 ± 0.531
6.733LysLeu: 6.733 ± 0.422
2.077LysMet: 2.077 ± 0.223
5.131LysAsn: 5.131 ± 0.347
2.503LysPro: 2.503 ± 0.222
3.304LysGln: 3.304 ± 0.29
3.229LysArg: 3.229 ± 0.344
4.68LysSer: 4.68 ± 0.36
4.68LysThr: 4.68 ± 0.372
6.407LysVal: 6.407 ± 0.439
0.826LysTrp: 0.826 ± 0.156
3.254LysTyr: 3.254 ± 0.292
0.0LysXaa: 0.0 ± 0.0
Leu
6.207LeuAla: 6.207 ± 0.429
0.776LeuCys: 0.776 ± 0.136
5.707LeuAsp: 5.707 ± 0.369
7.383LeuGlu: 7.383 ± 0.532
3.454LeuPhe: 3.454 ± 0.321
5.556LeuGly: 5.556 ± 0.349
1.001LeuHis: 1.001 ± 0.187
4.28LeuIle: 4.28 ± 0.366
6.207LeuLys: 6.207 ± 0.416
7.058LeuLeu: 7.058 ± 0.51
2.002LeuMet: 2.002 ± 0.22
5.006LeuAsn: 5.006 ± 0.363
3.329LeuPro: 3.329 ± 0.305
2.803LeuGln: 2.803 ± 0.297
3.829LeuArg: 3.829 ± 0.3
5.556LeuSer: 5.556 ± 0.389
5.306LeuThr: 5.306 ± 0.449
6.432LeuVal: 6.432 ± 0.478
0.851LeuTrp: 0.851 ± 0.144
3.254LeuTyr: 3.254 ± 0.279
0.0LeuXaa: 0.0 ± 0.0
Met
1.677MetAla: 1.677 ± 0.21
0.2MetCys: 0.2 ± 0.088
1.001MetAsp: 1.001 ± 0.129
1.777MetGlu: 1.777 ± 0.246
1.101MetPhe: 1.101 ± 0.152
1.176MetGly: 1.176 ± 0.191
0.15MetHis: 0.15 ± 0.058
1.327MetIle: 1.327 ± 0.177
2.278MetLys: 2.278 ± 0.29
2.178MetLeu: 2.178 ± 0.279
0.35MetMet: 0.35 ± 0.079
1.301MetAsn: 1.301 ± 0.164
1.051MetPro: 1.051 ± 0.186
0.926MetGln: 0.926 ± 0.151
1.276MetArg: 1.276 ± 0.173
2.127MetSer: 2.127 ± 0.222
1.902MetThr: 1.902 ± 0.223
1.452MetVal: 1.452 ± 0.213
0.25MetTrp: 0.25 ± 0.075
1.101MetTyr: 1.101 ± 0.155
0.0MetXaa: 0.0 ± 0.0
Asn
2.728AsnAla: 2.728 ± 0.304
0.2AsnCys: 0.2 ± 0.07
2.428AsnAsp: 2.428 ± 0.211
3.729AsnGlu: 3.729 ± 0.291
2.428AsnPhe: 2.428 ± 0.253
3.279AsnGly: 3.279 ± 0.272
1.051AsnHis: 1.051 ± 0.173
4.13AsnIle: 4.13 ± 0.337
5.782AsnLys: 5.782 ± 0.348
4.856AsnLeu: 4.856 ± 0.308
1.777AsnMet: 1.777 ± 0.201
3.404AsnAsn: 3.404 ± 0.3
2.077AsnPro: 2.077 ± 0.225
1.827AsnGln: 1.827 ± 0.2
2.403AsnArg: 2.403 ± 0.226
3.679AsnSer: 3.679 ± 0.379
4.105AsnThr: 4.105 ± 0.317
3.379AsnVal: 3.379 ± 0.294
0.801AsnTrp: 0.801 ± 0.14
2.503AsnTyr: 2.503 ± 0.239
0.0AsnXaa: 0.0 ± 0.0
Pro
1.777ProAla: 1.777 ± 0.265
0.125ProCys: 0.125 ± 0.059
1.952ProAsp: 1.952 ± 0.237
2.378ProGlu: 2.378 ± 0.245
1.327ProPhe: 1.327 ± 0.158
0.4ProGly: 0.4 ± 0.114
0.451ProHis: 0.451 ± 0.099
1.602ProIle: 1.602 ± 0.197
2.753ProLys: 2.753 ± 0.304
2.428ProLeu: 2.428 ± 0.24
0.876ProMet: 0.876 ± 0.173
1.602ProAsn: 1.602 ± 0.198
0.701ProPro: 0.701 ± 0.14
1.201ProGln: 1.201 ± 0.201
0.901ProArg: 0.901 ± 0.146
2.278ProSer: 2.278 ± 0.294
2.278ProThr: 2.278 ± 0.274
1.852ProVal: 1.852 ± 0.272
0.2ProTrp: 0.2 ± 0.066
1.427ProTyr: 1.427 ± 0.233
0.0ProXaa: 0.0 ± 0.0
Gln
2.928GlnAla: 2.928 ± 0.364
0.075GlnCys: 0.075 ± 0.041
1.827GlnAsp: 1.827 ± 0.204
2.678GlnGlu: 2.678 ± 0.275
1.176GlnPhe: 1.176 ± 0.213
2.253GlnGly: 2.253 ± 0.236
0.375GlnHis: 0.375 ± 0.079
1.752GlnIle: 1.752 ± 0.209
2.603GlnLys: 2.603 ± 0.252
3.079GlnLeu: 3.079 ± 0.278
0.876GlnMet: 0.876 ± 0.157
1.226GlnAsn: 1.226 ± 0.156
0.876GlnPro: 0.876 ± 0.234
2.178GlnGln: 2.178 ± 0.638
1.352GlnArg: 1.352 ± 0.196
2.027GlnSer: 2.027 ± 0.294
1.852GlnThr: 1.852 ± 0.197
2.803GlnVal: 2.803 ± 0.285
0.125GlnTrp: 0.125 ± 0.054
1.176GlnTyr: 1.176 ± 0.201
0.0GlnXaa: 0.0 ± 0.0
Arg
2.303ArgAla: 2.303 ± 0.297
0.175ArgCys: 0.175 ± 0.062
2.803ArgAsp: 2.803 ± 0.233
3.704ArgGlu: 3.704 ± 0.35
1.777ArgPhe: 1.777 ± 0.216
2.553ArgGly: 2.553 ± 0.285
0.626ArgHis: 0.626 ± 0.114
2.803ArgIle: 2.803 ± 0.256
3.729ArgLys: 3.729 ± 0.287
3.729ArgLeu: 3.729 ± 0.313
1.001ArgMet: 1.001 ± 0.174
2.653ArgAsn: 2.653 ± 0.263
0.651ArgPro: 0.651 ± 0.126
1.402ArgGln: 1.402 ± 0.176
1.552ArgArg: 1.552 ± 0.209
2.077ArgSer: 2.077 ± 0.26
2.528ArgThr: 2.528 ± 0.258
3.204ArgVal: 3.204 ± 0.284
0.3ArgTrp: 0.3 ± 0.084
2.027ArgTyr: 2.027 ± 0.268
0.0ArgXaa: 0.0 ± 0.0
Ser
3.654SerAla: 3.654 ± 0.291
0.476SerCys: 0.476 ± 0.124
3.529SerAsp: 3.529 ± 0.353
4.28SerGlu: 4.28 ± 0.377
3.054SerPhe: 3.054 ± 0.306
3.579SerGly: 3.579 ± 0.406
1.251SerHis: 1.251 ± 0.181
5.231SerIle: 5.231 ± 0.375
6.057SerLys: 6.057 ± 0.384
6.332SerLeu: 6.332 ± 0.377
1.777SerMet: 1.777 ± 0.204
3.604SerAsn: 3.604 ± 0.316
1.852SerPro: 1.852 ± 0.255
2.178SerGln: 2.178 ± 0.231
3.279SerArg: 3.279 ± 0.3
5.256SerSer: 5.256 ± 0.516
4.055SerThr: 4.055 ± 0.325
5.031SerVal: 5.031 ± 0.346
0.751SerTrp: 0.751 ± 0.19
3.129SerTyr: 3.129 ± 0.302
0.0SerXaa: 0.0 ± 0.0
Thr
4.155ThrAla: 4.155 ± 0.414
0.325ThrCys: 0.325 ± 0.089
3.654ThrAsp: 3.654 ± 0.283
4.78ThrGlu: 4.78 ± 0.377
3.229ThrPhe: 3.229 ± 0.321
4.38ThrGly: 4.38 ± 0.371
1.176ThrHis: 1.176 ± 0.178
4.355ThrIle: 4.355 ± 0.32
4.755ThrLys: 4.755 ± 0.36
5.256ThrLeu: 5.256 ± 0.396
1.076ThrMet: 1.076 ± 0.151
2.753ThrAsn: 2.753 ± 0.224
2.328ThrPro: 2.328 ± 0.22
1.402ThrGln: 1.402 ± 0.176
2.102ThrArg: 2.102 ± 0.236
4.405ThrSer: 4.405 ± 0.34
3.879ThrThr: 3.879 ± 0.345
5.106ThrVal: 5.106 ± 0.413
0.751ThrTrp: 0.751 ± 0.151
2.878ThrTyr: 2.878 ± 0.299
0.0ThrXaa: 0.0 ± 0.0
Val
4.63ValAla: 4.63 ± 0.275
0.526ValCys: 0.526 ± 0.11
4.806ValAsp: 4.806 ± 0.347
6.082ValGlu: 6.082 ± 0.434
2.928ValPhe: 2.928 ± 0.336
3.955ValGly: 3.955 ± 0.29
1.001ValHis: 1.001 ± 0.177
4.956ValIle: 4.956 ± 0.452
5.657ValLys: 5.657 ± 0.339
5.456ValLeu: 5.456 ± 0.411
1.527ValMet: 1.527 ± 0.232
3.955ValAsn: 3.955 ± 0.279
2.428ValPro: 2.428 ± 0.268
2.328ValGln: 2.328 ± 0.267
2.728ValArg: 2.728 ± 0.261
5.782ValSer: 5.782 ± 0.433
5.006ValThr: 5.006 ± 0.459
5.331ValVal: 5.331 ± 0.378
0.601ValTrp: 0.601 ± 0.118
3.104ValTyr: 3.104 ± 0.312
0.0ValXaa: 0.0 ± 0.0
Trp
0.451TrpAla: 0.451 ± 0.1
0.175TrpCys: 0.175 ± 0.066
0.701TrpAsp: 0.701 ± 0.159
0.801TrpGlu: 0.801 ± 0.144
0.375TrpPhe: 0.375 ± 0.101
0.751TrpGly: 0.751 ± 0.163
0.275TrpHis: 0.275 ± 0.078
0.451TrpIle: 0.451 ± 0.095
0.726TrpLys: 0.726 ± 0.164
0.851TrpLeu: 0.851 ± 0.152
0.1TrpMet: 0.1 ± 0.046
0.551TrpAsn: 0.551 ± 0.123
0.0TrpPro: 0.0 ± 0.0
0.275TrpGln: 0.275 ± 0.069
0.25TrpArg: 0.25 ± 0.077
0.425TrpSer: 0.425 ± 0.096
0.676TrpThr: 0.676 ± 0.159
0.726TrpVal: 0.726 ± 0.121
0.25TrpTrp: 0.25 ± 0.096
0.726TrpTyr: 0.726 ± 0.127
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.303TyrAla: 2.303 ± 0.243
0.526TyrCys: 0.526 ± 0.115
2.653TyrAsp: 2.653 ± 0.247
3.479TyrGlu: 3.479 ± 0.277
1.552TyrPhe: 1.552 ± 0.203
2.278TyrGly: 2.278 ± 0.273
0.826TyrHis: 0.826 ± 0.164
3.279TyrIle: 3.279 ± 0.333
3.729TyrLys: 3.729 ± 0.295
3.704TyrLeu: 3.704 ± 0.385
1.201TyrMet: 1.201 ± 0.207
2.528TyrAsn: 2.528 ± 0.2
1.352TyrPro: 1.352 ± 0.197
1.702TyrGln: 1.702 ± 0.25
2.378TyrArg: 2.378 ± 0.267
3.254TyrSer: 3.254 ± 0.308
3.254TyrThr: 3.254 ± 0.359
2.778TyrVal: 2.778 ± 0.273
0.3TyrTrp: 0.3 ± 0.086
2.077TyrTyr: 2.077 ± 0.251
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 190 proteins (39955 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski