Amino acid dipepetide frequency for Atopostipes suicloacalis DSM 15692

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.483AlaAla: 4.483 ± 0.109
0.356AlaCys: 0.356 ± 0.025
3.65AlaAsp: 3.65 ± 0.08
4.913AlaGlu: 4.913 ± 0.107
2.903AlaPhe: 2.903 ± 0.071
4.719AlaGly: 4.719 ± 0.094
1.176AlaHis: 1.176 ± 0.042
5.532AlaIle: 5.532 ± 0.102
4.098AlaLys: 4.098 ± 0.09
6.484AlaLeu: 6.484 ± 0.112
1.799AlaMet: 1.799 ± 0.063
2.877AlaAsn: 2.877 ± 0.066
1.876AlaPro: 1.876 ± 0.056
2.423AlaGln: 2.423 ± 0.068
2.478AlaArg: 2.478 ± 0.064
3.74AlaSer: 3.74 ± 0.077
3.613AlaThr: 3.613 ± 0.082
4.445AlaVal: 4.445 ± 0.095
0.487AlaTrp: 0.487 ± 0.031
2.42AlaTyr: 2.42 ± 0.068
0.0AlaXaa: 0.0 ± 0.0
Cys
0.266CysAla: 0.266 ± 0.029
0.067CysCys: 0.067 ± 0.014
0.239CysAsp: 0.239 ± 0.019
0.273CysGlu: 0.273 ± 0.025
0.192CysPhe: 0.192 ± 0.021
0.442CysGly: 0.442 ± 0.032
0.115CysHis: 0.115 ± 0.014
0.258CysIle: 0.258 ± 0.021
0.171CysLys: 0.171 ± 0.019
0.331CysLeu: 0.331 ± 0.023
0.089CysMet: 0.089 ± 0.011
0.151CysAsn: 0.151 ± 0.016
0.226CysPro: 0.226 ± 0.02
0.159CysGln: 0.159 ± 0.019
0.179CysArg: 0.179 ± 0.018
0.283CysSer: 0.283 ± 0.025
0.219CysThr: 0.219 ± 0.019
0.218CysVal: 0.218 ± 0.019
0.025CysTrp: 0.025 ± 0.006
0.137CysTyr: 0.137 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
3.487AspAla: 3.487 ± 0.077
0.233AspCys: 0.233 ± 0.018
2.942AspAsp: 2.942 ± 0.094
5.77AspGlu: 5.77 ± 0.122
3.017AspPhe: 3.017 ± 0.071
3.461AspGly: 3.461 ± 0.108
1.235AspHis: 1.235 ± 0.048
4.562AspIle: 4.562 ± 0.098
3.377AspLys: 3.377 ± 0.084
5.997AspLeu: 5.997 ± 0.114
1.412AspMet: 1.412 ± 0.049
2.326AspAsn: 2.326 ± 0.06
2.033AspPro: 2.033 ± 0.066
2.324AspGln: 2.324 ± 0.066
2.318AspArg: 2.318 ± 0.069
3.342AspSer: 3.342 ± 0.084
3.211AspThr: 3.211 ± 0.092
3.899AspVal: 3.899 ± 0.09
0.659AspTrp: 0.659 ± 0.035
2.885AspTyr: 2.885 ± 0.065
0.0AspXaa: 0.0 ± 0.0
Glu
5.999GluAla: 5.999 ± 0.124
0.231GluCys: 0.231 ± 0.022
5.494GluAsp: 5.494 ± 0.116
9.652GluGlu: 9.652 ± 0.157
2.887GluPhe: 2.887 ± 0.069
4.63GluGly: 4.63 ± 0.099
1.519GluHis: 1.519 ± 0.045
6.858GluIle: 6.858 ± 0.114
6.784GluLys: 6.784 ± 0.123
7.646GluLeu: 7.646 ± 0.125
2.572GluMet: 2.572 ± 0.059
5.166GluAsn: 5.166 ± 0.098
2.308GluPro: 2.308 ± 0.082
3.405GluGln: 3.405 ± 0.09
3.305GluArg: 3.305 ± 0.085
3.817GluSer: 3.817 ± 0.088
4.577GluThr: 4.577 ± 0.1
5.954GluVal: 5.954 ± 0.114
0.776GluTrp: 0.776 ± 0.041
2.853GluTyr: 2.853 ± 0.07
0.0GluXaa: 0.0 ± 0.0
Phe
2.562PheAla: 2.562 ± 0.072
0.182PheCys: 0.182 ± 0.015
2.947PheAsp: 2.947 ± 0.07
3.313PheGlu: 3.313 ± 0.088
2.175PhePhe: 2.175 ± 0.066
3.143PheGly: 3.143 ± 0.083
0.731PheHis: 0.731 ± 0.044
3.924PheIle: 3.924 ± 0.106
2.522PheLys: 2.522 ± 0.064
4.254PheLeu: 4.254 ± 0.099
1.108PheMet: 1.108 ± 0.05
2.329PheAsn: 2.329 ± 0.059
1.581PhePro: 1.581 ± 0.053
1.417PheGln: 1.417 ± 0.056
1.367PheArg: 1.367 ± 0.051
3.4PheSer: 3.4 ± 0.085
2.488PheThr: 2.488 ± 0.064
2.992PheVal: 2.992 ± 0.072
0.43PheTrp: 0.43 ± 0.027
1.951PheTyr: 1.951 ± 0.069
0.0PheXaa: 0.0 ± 0.0
Gly
4.317GlyAla: 4.317 ± 0.113
0.318GlyCys: 0.318 ± 0.026
3.276GlyAsp: 3.276 ± 0.094
4.699GlyGlu: 4.699 ± 0.111
3.092GlyPhe: 3.092 ± 0.077
4.297GlyGly: 4.297 ± 0.115
1.24GlyHis: 1.24 ± 0.052
5.457GlyIle: 5.457 ± 0.108
4.158GlyLys: 4.158 ± 0.091
6.295GlyLeu: 6.295 ± 0.107
1.819GlyMet: 1.819 ± 0.063
2.738GlyAsn: 2.738 ± 0.07
1.529GlyPro: 1.529 ± 0.049
2.264GlyGln: 2.264 ± 0.066
2.59GlyArg: 2.59 ± 0.079
3.862GlySer: 3.862 ± 0.09
4.001GlyThr: 4.001 ± 0.084
4.751GlyVal: 4.751 ± 0.098
0.664GlyTrp: 0.664 ± 0.035
2.778GlyTyr: 2.778 ± 0.063
0.0GlyXaa: 0.0 ± 0.0
His
1.113HisAla: 1.113 ± 0.045
0.095HisCys: 0.095 ± 0.012
0.954HisAsp: 0.954 ± 0.045
1.486HisGlu: 1.486 ± 0.051
0.999HisPhe: 0.999 ± 0.044
1.222HisGly: 1.222 ± 0.048
0.517HisHis: 0.517 ± 0.035
1.314HisIle: 1.314 ± 0.043
1.043HisLys: 1.043 ± 0.044
2.08HisLeu: 2.08 ± 0.062
0.467HisMet: 0.467 ± 0.027
0.733HisAsn: 0.733 ± 0.035
1.027HisPro: 1.027 ± 0.041
0.828HisGln: 0.828 ± 0.038
0.758HisArg: 0.758 ± 0.036
1.17HisSer: 1.17 ± 0.048
1.058HisThr: 1.058 ± 0.038
1.138HisVal: 1.138 ± 0.043
0.233HisTrp: 0.233 ± 0.02
0.838HisTyr: 0.838 ± 0.038
0.0HisXaa: 0.0 ± 0.0
Ile
5.581IleAla: 5.581 ± 0.1
0.35IleCys: 0.35 ± 0.023
5.102IleAsp: 5.102 ± 0.096
6.772IleGlu: 6.772 ± 0.096
3.464IlePhe: 3.464 ± 0.093
5.531IleGly: 5.531 ± 0.111
1.575IleHis: 1.575 ± 0.054
6.176IleIle: 6.176 ± 0.122
4.593IleLys: 4.593 ± 0.082
7.726IleLeu: 7.726 ± 0.157
1.826IleMet: 1.826 ± 0.055
3.777IleAsn: 3.777 ± 0.08
3.174IlePro: 3.174 ± 0.072
3.342IleGln: 3.342 ± 0.078
3.002IleArg: 3.002 ± 0.078
5.042IleSer: 5.042 ± 0.097
4.368IleThr: 4.368 ± 0.088
5.514IleVal: 5.514 ± 0.108
0.554IleTrp: 0.554 ± 0.032
2.875IleTyr: 2.875 ± 0.075
0.0IleXaa: 0.0 ± 0.0
Lys
4.043LysAla: 4.043 ± 0.086
0.202LysCys: 0.202 ± 0.02
4.175LysAsp: 4.175 ± 0.094
7.351LysGlu: 7.351 ± 0.113
2.018LysPhe: 2.018 ± 0.063
3.533LysGly: 3.533 ± 0.074
1.145LysHis: 1.145 ± 0.046
5.198LysIle: 5.198 ± 0.106
5.254LysLys: 5.254 ± 0.116
5.189LysLeu: 5.189 ± 0.089
1.919LysMet: 1.919 ± 0.056
3.974LysAsn: 3.974 ± 0.084
1.767LysPro: 1.767 ± 0.057
2.656LysGln: 2.656 ± 0.082
2.903LysArg: 2.903 ± 0.085
3.236LysSer: 3.236 ± 0.082
3.596LysThr: 3.596 ± 0.081
3.919LysVal: 3.919 ± 0.075
0.584LysTrp: 0.584 ± 0.031
2.508LysTyr: 2.508 ± 0.066
0.0LysXaa: 0.0 ± 0.0
Leu
6.593LeuAla: 6.593 ± 0.123
0.377LeuCys: 0.377 ± 0.026
5.713LeuAsp: 5.713 ± 0.085
7.82LeuGlu: 7.82 ± 0.12
4.587LeuPhe: 4.587 ± 0.122
6.034LeuGly: 6.034 ± 0.112
1.561LeuHis: 1.561 ± 0.049
7.348LeuIle: 7.348 ± 0.141
6.029LeuLys: 6.029 ± 0.122
9.418LeuLeu: 9.418 ± 0.161
2.569LeuMet: 2.569 ± 0.069
5.243LeuAsn: 5.243 ± 0.107
3.74LeuPro: 3.74 ± 0.088
3.139LeuGln: 3.139 ± 0.09
3.466LeuArg: 3.466 ± 0.091
6.69LeuSer: 6.69 ± 0.102
5.808LeuThr: 5.808 ± 0.108
6.202LeuVal: 6.202 ± 0.111
0.659LeuTrp: 0.659 ± 0.034
3.256LeuTyr: 3.256 ± 0.079
0.0LeuXaa: 0.0 ± 0.0
Met
1.769MetAla: 1.769 ± 0.055
0.075MetCys: 0.075 ± 0.01
1.772MetAsp: 1.772 ± 0.063
1.899MetGlu: 1.899 ± 0.054
0.895MetPhe: 0.895 ± 0.044
1.672MetGly: 1.672 ± 0.054
0.413MetHis: 0.413 ± 0.027
1.976MetIle: 1.976 ± 0.067
2.08MetLys: 2.08 ± 0.061
2.184MetLeu: 2.184 ± 0.063
0.706MetMet: 0.706 ± 0.034
1.688MetAsn: 1.688 ± 0.049
0.87MetPro: 0.87 ± 0.039
0.889MetGln: 0.889 ± 0.04
1.099MetArg: 1.099 ± 0.045
1.628MetSer: 1.628 ± 0.052
1.633MetThr: 1.633 ± 0.048
1.675MetVal: 1.675 ± 0.064
0.151MetTrp: 0.151 ± 0.015
0.735MetTyr: 0.735 ± 0.038
0.0MetXaa: 0.0 ± 0.0
Asn
2.719AsnAla: 2.719 ± 0.063
0.187AsnCys: 0.187 ± 0.018
2.766AsnAsp: 2.766 ± 0.074
4.319AsnGlu: 4.319 ± 0.108
2.127AsnPhe: 2.127 ± 0.06
3.086AsnGly: 3.086 ± 0.088
1.242AsnHis: 1.242 ± 0.045
4.319AsnIle: 4.319 ± 0.088
3.586AsnLys: 3.586 ± 0.089
4.655AsnLeu: 4.655 ± 0.088
1.2AsnMet: 1.2 ± 0.043
2.614AsnAsn: 2.614 ± 0.084
2.088AsnPro: 2.088 ± 0.055
2.413AsnGln: 2.413 ± 0.067
2.338AsnArg: 2.338 ± 0.067
2.446AsnSer: 2.446 ± 0.059
2.517AsnThr: 2.517 ± 0.067
3.077AsnVal: 3.077 ± 0.065
0.567AsnTrp: 0.567 ± 0.03
2.224AsnTyr: 2.224 ± 0.062
0.0AsnXaa: 0.0 ± 0.0
Pro
2.078ProAla: 2.078 ± 0.067
0.132ProCys: 0.132 ± 0.017
1.991ProAsp: 1.991 ± 0.062
3.4ProGlu: 3.4 ± 0.088
1.802ProPhe: 1.802 ± 0.057
1.941ProGly: 1.941 ± 0.056
0.634ProHis: 0.634 ± 0.034
2.923ProIle: 2.923 ± 0.077
2.167ProLys: 2.167 ± 0.066
3.123ProLeu: 3.123 ± 0.071
0.748ProMet: 0.748 ± 0.035
1.812ProAsn: 1.812 ± 0.049
0.694ProPro: 0.694 ± 0.032
0.996ProGln: 0.996 ± 0.037
0.996ProArg: 0.996 ± 0.035
2.038ProSer: 2.038 ± 0.062
2.113ProThr: 2.113 ± 0.062
2.338ProVal: 2.338 ± 0.063
0.284ProTrp: 0.284 ± 0.024
1.463ProTyr: 1.463 ± 0.052
0.0ProXaa: 0.0 ± 0.0
Gln
2.768GlnAla: 2.768 ± 0.068
0.092GlnCys: 0.092 ± 0.015
1.754GlnAsp: 1.754 ± 0.056
3.268GlnGlu: 3.268 ± 0.085
1.643GlnPhe: 1.643 ± 0.051
1.955GlnGly: 1.955 ± 0.062
0.602GlnHis: 0.602 ± 0.03
2.915GlnIle: 2.915 ± 0.073
2.831GlnLys: 2.831 ± 0.074
4.008GlnLeu: 4.008 ± 0.131
1.091GlnMet: 1.091 ± 0.045
2.005GlnAsn: 2.005 ± 0.057
1.158GlnPro: 1.158 ± 0.043
1.707GlnGln: 1.707 ± 0.066
1.476GlnArg: 1.476 ± 0.057
2.137GlnSer: 2.137 ± 0.066
2.299GlnThr: 2.299 ± 0.065
2.467GlnVal: 2.467 ± 0.062
0.335GlnTrp: 0.335 ± 0.024
1.347GlnTyr: 1.347 ± 0.054
0.0GlnXaa: 0.0 ± 0.0
Arg
2.277ArgAla: 2.277 ± 0.062
0.156ArgCys: 0.156 ± 0.017
2.005ArgAsp: 2.005 ± 0.064
3.318ArgGlu: 3.318 ± 0.082
1.734ArgPhe: 1.734 ± 0.055
2.259ArgGly: 2.259 ± 0.066
0.718ArgHis: 0.718 ± 0.036
3.096ArgIle: 3.096 ± 0.074
2.907ArgLys: 2.907 ± 0.08
3.824ArgLeu: 3.824 ± 0.088
1.178ArgMet: 1.178 ± 0.045
1.898ArgAsn: 1.898 ± 0.055
1.404ArgPro: 1.404 ± 0.054
1.545ArgGln: 1.545 ± 0.055
1.931ArgArg: 1.931 ± 0.068
2.031ArgSer: 2.031 ± 0.056
2.063ArgThr: 2.063 ± 0.051
2.634ArgVal: 2.634 ± 0.062
0.303ArgTrp: 0.303 ± 0.025
1.627ArgTyr: 1.627 ± 0.052
0.0ArgXaa: 0.0 ± 0.0
Ser
3.382SerAla: 3.382 ± 0.092
0.234SerCys: 0.234 ± 0.021
3.271SerAsp: 3.271 ± 0.079
4.624SerGlu: 4.624 ± 0.097
3.216SerPhe: 3.216 ± 0.082
4.436SerGly: 4.436 ± 0.091
1.163SerHis: 1.163 ± 0.043
4.878SerIle: 4.878 ± 0.087
3.84SerLys: 3.84 ± 0.089
5.949SerLeu: 5.949 ± 0.111
1.422SerMet: 1.422 ± 0.047
2.917SerAsn: 2.917 ± 0.075
1.801SerPro: 1.801 ± 0.054
2.072SerGln: 2.072 ± 0.069
2.217SerArg: 2.217 ± 0.074
3.805SerSer: 3.805 ± 0.089
3.231SerThr: 3.231 ± 0.073
3.814SerVal: 3.814 ± 0.083
0.582SerTrp: 0.582 ± 0.035
2.383SerTyr: 2.383 ± 0.066
0.0SerXaa: 0.0 ± 0.0
Thr
3.539ThrAla: 3.539 ± 0.075
0.179ThrCys: 0.179 ± 0.018
3.385ThrAsp: 3.385 ± 0.082
4.369ThrGlu: 4.369 ± 0.102
2.589ThrPhe: 2.589 ± 0.073
4.153ThrGly: 4.153 ± 0.089
1.208ThrHis: 1.208 ± 0.041
4.843ThrIle: 4.843 ± 0.099
3.358ThrLys: 3.358 ± 0.075
5.556ThrLeu: 5.556 ± 0.089
1.31ThrMet: 1.31 ± 0.053
2.768ThrAsn: 2.768 ± 0.068
2.308ThrPro: 2.308 ± 0.071
1.888ThrGln: 1.888 ± 0.06
1.983ThrArg: 1.983 ± 0.054
3.26ThrSer: 3.26 ± 0.079
3.452ThrThr: 3.452 ± 0.071
4.158ThrVal: 4.158 ± 0.09
0.459ThrTrp: 0.459 ± 0.03
2.048ThrTyr: 2.048 ± 0.067
0.0ThrXaa: 0.0 ± 0.0
Val
4.756ValAla: 4.756 ± 0.106
0.318ValCys: 0.318 ± 0.022
4.18ValAsp: 4.18 ± 0.091
5.544ValGlu: 5.544 ± 0.11
2.99ValPhe: 2.99 ± 0.081
4.521ValGly: 4.521 ± 0.098
1.282ValHis: 1.282 ± 0.047
5.313ValIle: 5.313 ± 0.108
3.645ValLys: 3.645 ± 0.089
6.486ValLeu: 6.486 ± 0.116
1.54ValMet: 1.54 ± 0.054
3.106ValAsn: 3.106 ± 0.07
2.406ValPro: 2.406 ± 0.06
2.174ValGln: 2.174 ± 0.06
2.485ValArg: 2.485 ± 0.067
4.496ValSer: 4.496 ± 0.075
3.959ValThr: 3.959 ± 0.082
4.61ValVal: 4.61 ± 0.101
0.464ValTrp: 0.464 ± 0.028
2.301ValTyr: 2.301 ± 0.064
0.0ValXaa: 0.0 ± 0.0
Trp
0.492TrpAla: 0.492 ± 0.031
0.042TrpCys: 0.042 ± 0.007
0.494TrpAsp: 0.494 ± 0.031
0.651TrpGlu: 0.651 ± 0.032
0.423TrpPhe: 0.423 ± 0.033
0.537TrpGly: 0.537 ± 0.03
0.129TrpHis: 0.129 ± 0.017
0.671TrpIle: 0.671 ± 0.031
0.544TrpLys: 0.544 ± 0.03
1.012TrpLeu: 1.012 ± 0.038
0.284TrpMet: 0.284 ± 0.024
0.509TrpAsn: 0.509 ± 0.028
0.214TrpPro: 0.214 ± 0.02
0.378TrpGln: 0.378 ± 0.023
0.38TrpArg: 0.38 ± 0.026
0.475TrpSer: 0.475 ± 0.028
0.464TrpThr: 0.464 ± 0.026
0.532TrpVal: 0.532 ± 0.029
0.102TrpTrp: 0.102 ± 0.013
0.355TrpTyr: 0.355 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.247TyrAla: 2.247 ± 0.061
0.213TyrCys: 0.213 ± 0.019
2.38TyrAsp: 2.38 ± 0.067
2.99TyrGlu: 2.99 ± 0.073
2.063TyrPhe: 2.063 ± 0.057
2.577TyrGly: 2.577 ± 0.07
0.865TyrHis: 0.865 ± 0.041
2.783TyrIle: 2.783 ± 0.076
2.185TyrLys: 2.185 ± 0.068
4.035TyrLeu: 4.035 ± 0.079
0.75TyrMet: 0.75 ± 0.036
1.862TyrAsn: 1.862 ± 0.058
1.469TyrPro: 1.469 ± 0.048
1.839TyrGln: 1.839 ± 0.066
1.635TyrArg: 1.635 ± 0.052
2.338TyrSer: 2.338 ± 0.064
2.142TyrThr: 2.142 ± 0.061
2.241TyrVal: 2.241 ± 0.064
0.37TyrTrp: 0.37 ± 0.027
1.727TyrTyr: 1.727 ± 0.064
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1926 proteins (597593 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski