Amino acid dipepetide frequency for Persimmon cryptic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.979AlaAla: 8.979 ± 1.86
1.122AlaCys: 1.122 ± 0.778
4.489AlaAsp: 4.489 ± 0.202
2.245AlaGlu: 2.245 ± 0.101
5.612AlaPhe: 5.612 ± 1.929
5.612AlaGly: 5.612 ± 0.98
2.245AlaHis: 2.245 ± 0.101
7.856AlaIle: 7.856 ± 0.373
4.489AlaLys: 4.489 ± 1.252
4.489AlaLeu: 4.489 ± 1.252
1.122AlaMet: 1.122 ± 0.677
4.489AlaAsn: 4.489 ± 0.202
5.612AlaPro: 5.612 ± 2.435
2.245AlaGln: 2.245 ± 0.101
2.245AlaArg: 2.245 ± 0.101
1.122AlaSer: 1.122 ± 0.778
5.612AlaThr: 5.612 ± 0.98
3.367AlaVal: 3.367 ± 0.879
2.245AlaTrp: 2.245 ± 0.101
5.612AlaTyr: 5.612 ± 2.435
0.0AlaXaa: 0.0 ± 0.0
Cys
1.122CysAla: 1.122 ± 0.677
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.122CysGlu: 1.122 ± 0.677
0.0CysPhe: 0.0 ± 0.0
2.245CysGly: 2.245 ± 1.353
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.122CysLeu: 1.122 ± 0.677
0.0CysMet: 0.0 ± 0.0
1.122CysAsn: 1.122 ± 0.778
0.0CysPro: 0.0 ± 0.0
1.122CysGln: 1.122 ± 0.778
1.122CysArg: 1.122 ± 0.677
1.122CysSer: 1.122 ± 0.778
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.122CysTrp: 1.122 ± 0.778
6.734CysTyr: 6.734 ± 1.151
0.0CysXaa: 0.0 ± 0.0
Asp
1.122AspAla: 1.122 ± 0.677
1.122AspCys: 1.122 ± 0.677
3.367AspAsp: 3.367 ± 0.576
3.367AspGlu: 3.367 ± 0.576
1.122AspPhe: 1.122 ± 0.677
2.245AspGly: 2.245 ± 1.353
0.0AspHis: 0.0 ± 0.0
3.367AspIle: 3.367 ± 2.03
0.0AspLys: 0.0 ± 0.0
6.734AspLeu: 6.734 ± 0.304
0.0AspMet: 0.0 ± 0.0
1.122AspAsn: 1.122 ± 0.677
4.489AspPro: 4.489 ± 0.202
2.245AspGln: 2.245 ± 0.101
3.367AspArg: 3.367 ± 2.334
3.367AspSer: 3.367 ± 0.879
2.245AspThr: 2.245 ± 0.101
5.612AspVal: 5.612 ± 0.474
4.489AspTrp: 4.489 ± 1.657
1.122AspTyr: 1.122 ± 0.677
0.0AspXaa: 0.0 ± 0.0
Glu
1.122GluAla: 1.122 ± 0.778
0.0GluCys: 0.0 ± 0.0
4.489GluAsp: 4.489 ± 1.657
1.122GluGlu: 1.122 ± 0.677
3.367GluPhe: 3.367 ± 2.03
6.734GluGly: 6.734 ± 2.606
1.122GluHis: 1.122 ± 0.677
2.245GluIle: 2.245 ± 1.353
1.122GluLys: 1.122 ± 0.677
6.734GluLeu: 6.734 ± 1.151
0.0GluMet: 0.0 ± 0.0
1.122GluAsn: 1.122 ± 0.778
1.122GluPro: 1.122 ± 0.677
4.489GluGln: 4.489 ± 1.252
5.612GluArg: 5.612 ± 1.929
6.734GluSer: 6.734 ± 1.758
2.245GluThr: 2.245 ± 0.101
1.122GluVal: 1.122 ± 0.677
0.0GluTrp: 0.0 ± 0.0
6.734GluTyr: 6.734 ± 0.304
0.0GluXaa: 0.0 ± 0.0
Phe
1.122PheAla: 1.122 ± 0.677
0.0PheCys: 0.0 ± 0.0
3.367PheAsp: 3.367 ± 2.03
3.367PheGlu: 3.367 ± 2.03
2.245PhePhe: 2.245 ± 1.556
2.245PheGly: 2.245 ± 1.556
3.367PheHis: 3.367 ± 0.576
1.122PheIle: 1.122 ± 0.677
2.245PheLys: 2.245 ± 0.101
4.489PheLeu: 4.489 ± 1.657
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
3.367PhePro: 3.367 ± 0.879
3.367PheGln: 3.367 ± 0.879
0.0PheArg: 0.0 ± 0.0
2.245PheSer: 2.245 ± 1.556
0.0PheThr: 0.0 ± 0.0
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.122PheTyr: 1.122 ± 0.677
0.0PheXaa: 0.0 ± 0.0
Gly
4.489GlyAla: 4.489 ± 0.202
1.122GlyCys: 1.122 ± 0.677
2.245GlyAsp: 2.245 ± 1.353
2.245GlyGlu: 2.245 ± 1.353
1.122GlyPhe: 1.122 ± 0.778
4.489GlyGly: 4.489 ± 1.252
1.122GlyHis: 1.122 ± 0.677
5.612GlyIle: 5.612 ± 0.98
2.245GlyLys: 2.245 ± 1.353
3.367GlyLeu: 3.367 ± 0.879
0.0GlyMet: 0.0 ± 0.0
4.489GlyAsn: 4.489 ± 1.657
3.367GlyPro: 3.367 ± 0.576
3.367GlyGln: 3.367 ± 0.879
5.612GlyArg: 5.612 ± 0.474
3.367GlySer: 3.367 ± 0.576
3.367GlyThr: 3.367 ± 2.03
2.245GlyVal: 2.245 ± 1.353
2.245GlyTrp: 2.245 ± 1.353
6.734GlyTyr: 6.734 ± 0.304
0.0GlyXaa: 0.0 ± 0.0
His
1.122HisAla: 1.122 ± 0.677
0.0HisCys: 0.0 ± 0.0
4.489HisAsp: 4.489 ± 0.202
2.245HisGlu: 2.245 ± 1.353
1.122HisPhe: 1.122 ± 0.778
2.245HisGly: 2.245 ± 0.101
0.0HisHis: 0.0 ± 0.0
6.734HisIle: 6.734 ± 0.304
2.245HisLys: 2.245 ± 1.353
1.122HisLeu: 1.122 ± 0.778
2.245HisMet: 2.245 ± 1.102
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.245HisArg: 2.245 ± 0.101
1.122HisSer: 1.122 ± 0.778
0.0HisThr: 0.0 ± 0.0
3.367HisVal: 3.367 ± 0.879
0.0HisTrp: 0.0 ± 0.0
2.245HisTyr: 2.245 ± 0.101
0.0HisXaa: 0.0 ± 0.0
Ile
12.346IleAla: 12.346 ± 0.171
2.245IleCys: 2.245 ± 1.353
2.245IleAsp: 2.245 ± 0.101
5.612IleGlu: 5.612 ± 1.929
0.0IlePhe: 0.0 ± 0.0
4.489IleGly: 4.489 ± 1.252
3.367IleHis: 3.367 ± 2.03
3.367IleIle: 3.367 ± 0.576
1.122IleLys: 1.122 ± 0.677
8.979IleLeu: 8.979 ± 0.405
2.245IleMet: 2.245 ± 1.556
6.734IleAsn: 6.734 ± 1.758
6.734IlePro: 6.734 ± 3.213
1.122IleGln: 1.122 ± 0.677
4.489IleArg: 4.489 ± 0.202
2.245IleSer: 2.245 ± 0.101
3.367IleThr: 3.367 ± 0.576
2.245IleVal: 2.245 ± 1.353
1.122IleTrp: 1.122 ± 0.677
1.122IleTyr: 1.122 ± 0.677
0.0IleXaa: 0.0 ± 0.0
Lys
2.245LysAla: 2.245 ± 1.353
1.122LysCys: 1.122 ± 0.677
0.0LysAsp: 0.0 ± 0.0
3.367LysGlu: 3.367 ± 0.576
0.0LysPhe: 0.0 ± 0.0
2.245LysGly: 2.245 ± 1.353
1.122LysHis: 1.122 ± 0.778
1.122LysIle: 1.122 ± 0.677
2.245LysLys: 2.245 ± 0.101
2.245LysLeu: 2.245 ± 0.101
0.0LysMet: 0.0 ± 0.0
2.245LysAsn: 2.245 ± 0.101
1.122LysPro: 1.122 ± 0.778
2.245LysGln: 2.245 ± 0.101
1.122LysArg: 1.122 ± 0.778
0.0LysSer: 0.0 ± 0.0
2.245LysThr: 2.245 ± 1.353
2.245LysVal: 2.245 ± 1.353
0.0LysTrp: 0.0 ± 0.0
1.122LysTyr: 1.122 ± 0.677
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
3.367LeuCys: 3.367 ± 0.576
4.489LeuAsp: 4.489 ± 0.202
4.489LeuGlu: 4.489 ± 0.202
2.245LeuPhe: 2.245 ± 0.101
4.489LeuGly: 4.489 ± 1.657
2.245LeuHis: 2.245 ± 1.556
5.612LeuIle: 5.612 ± 0.474
2.245LeuLys: 2.245 ± 0.101
7.856LeuLeu: 7.856 ± 1.828
0.0LeuMet: 0.0 ± 0.0
6.734LeuAsn: 6.734 ± 0.304
7.856LeuPro: 7.856 ± 1.082
4.489LeuGln: 4.489 ± 0.202
8.979LeuArg: 8.979 ± 2.505
6.734LeuSer: 6.734 ± 0.304
3.367LeuThr: 3.367 ± 2.03
2.245LeuVal: 2.245 ± 0.101
1.122LeuTrp: 1.122 ± 0.677
5.612LeuTyr: 5.612 ± 0.98
0.0LeuXaa: 0.0 ± 0.0
Met
2.245MetAla: 2.245 ± 0.101
0.0MetCys: 0.0 ± 0.0
2.245MetAsp: 2.245 ± 1.556
1.122MetGlu: 1.122 ± 0.778
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.122MetLys: 1.122 ± 0.677
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.122MetPro: 1.122 ± 0.778
1.122MetGln: 1.122 ± 0.778
0.0MetArg: 0.0 ± 0.0
1.122MetSer: 1.122 ± 0.778
1.122MetThr: 1.122 ± 0.677
0.0MetVal: 0.0 ± 0.0
2.245MetTrp: 2.245 ± 1.556
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.122AsnAla: 1.122 ± 0.778
0.0AsnCys: 0.0 ± 0.0
1.122AsnAsp: 1.122 ± 0.677
3.367AsnGlu: 3.367 ± 0.879
1.122AsnPhe: 1.122 ± 0.677
0.0AsnGly: 0.0 ± 0.0
5.612AsnHis: 5.612 ± 0.98
1.122AsnIle: 1.122 ± 0.778
1.122AsnLys: 1.122 ± 0.778
2.245AsnLeu: 2.245 ± 1.556
0.0AsnMet: 0.0 ± 0.576
2.245AsnAsn: 2.245 ± 1.556
3.367AsnPro: 3.367 ± 0.576
4.489AsnGln: 4.489 ± 1.657
1.122AsnArg: 1.122 ± 0.677
2.245AsnSer: 2.245 ± 0.101
4.489AsnThr: 4.489 ± 0.202
2.245AsnVal: 2.245 ± 0.101
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.734ProAla: 6.734 ± 3.213
1.122ProCys: 1.122 ± 0.778
2.245ProAsp: 2.245 ± 1.353
6.734ProGlu: 6.734 ± 1.151
3.367ProPhe: 3.367 ± 2.334
3.367ProGly: 3.367 ± 2.334
0.0ProHis: 0.0 ± 0.0
4.489ProIle: 4.489 ± 1.252
2.245ProLys: 2.245 ± 1.353
5.612ProLeu: 5.612 ± 2.435
1.122ProMet: 1.122 ± 0.778
4.489ProAsn: 4.489 ± 0.202
1.122ProPro: 1.122 ± 0.778
2.245ProGln: 2.245 ± 1.556
5.612ProArg: 5.612 ± 3.89
2.245ProSer: 2.245 ± 1.353
3.367ProThr: 3.367 ± 0.576
2.245ProVal: 2.245 ± 0.101
0.0ProTrp: 0.0 ± 0.0
2.245ProTyr: 2.245 ± 0.101
0.0ProXaa: 0.0 ± 0.0
Gln
7.856GlnAla: 7.856 ± 2.536
1.122GlnCys: 1.122 ± 0.677
4.489GlnAsp: 4.489 ± 1.252
4.489GlnGlu: 4.489 ± 0.202
2.245GlnPhe: 2.245 ± 1.556
3.367GlnGly: 3.367 ± 0.879
3.367GlnHis: 3.367 ± 0.879
3.367GlnIle: 3.367 ± 2.334
1.122GlnLys: 1.122 ± 0.778
3.367GlnLeu: 3.367 ± 2.03
1.122GlnMet: 1.122 ± 0.778
2.245GlnAsn: 2.245 ± 1.556
1.122GlnPro: 1.122 ± 0.778
3.367GlnGln: 3.367 ± 0.879
2.245GlnArg: 2.245 ± 0.101
2.245GlnSer: 2.245 ± 0.101
5.612GlnThr: 5.612 ± 2.435
1.122GlnVal: 1.122 ± 0.677
1.122GlnTrp: 1.122 ± 0.778
3.367GlnTyr: 3.367 ± 0.879
0.0GlnXaa: 0.0 ± 0.0
Arg
6.734ArgAla: 6.734 ± 2.606
1.122ArgCys: 1.122 ± 0.677
2.245ArgAsp: 2.245 ± 0.101
2.245ArgGlu: 2.245 ± 0.101
2.245ArgPhe: 2.245 ± 0.101
2.245ArgGly: 2.245 ± 1.353
1.122ArgHis: 1.122 ± 0.677
7.856ArgIle: 7.856 ± 0.373
1.122ArgLys: 1.122 ± 0.677
8.979ArgLeu: 8.979 ± 1.05
1.122ArgMet: 1.122 ± 0.778
0.0ArgAsn: 0.0 ± 0.0
3.367ArgPro: 3.367 ± 2.334
2.245ArgGln: 2.245 ± 0.101
5.612ArgArg: 5.612 ± 0.474
6.734ArgSer: 6.734 ± 0.304
4.489ArgThr: 4.489 ± 0.202
4.489ArgVal: 4.489 ± 0.202
0.0ArgTrp: 0.0 ± 0.0
4.489ArgTyr: 4.489 ± 1.657
0.0ArgXaa: 0.0 ± 0.0
Ser
6.734SerAla: 6.734 ± 1.151
0.0SerCys: 0.0 ± 0.0
2.245SerAsp: 2.245 ± 0.101
1.122SerGlu: 1.122 ± 0.677
2.245SerPhe: 2.245 ± 1.353
5.612SerGly: 5.612 ± 0.474
2.245SerHis: 2.245 ± 0.101
7.856SerIle: 7.856 ± 1.828
1.122SerLys: 1.122 ± 0.778
7.856SerLeu: 7.856 ± 0.373
0.0SerMet: 0.0 ± 0.0
0.0SerAsn: 0.0 ± 0.0
4.489SerPro: 4.489 ± 3.112
5.612SerGln: 5.612 ± 3.89
2.245SerArg: 2.245 ± 1.353
10.101SerSer: 10.101 ± 3.181
1.122SerThr: 1.122 ± 0.778
3.367SerVal: 3.367 ± 0.576
1.122SerTrp: 1.122 ± 0.778
2.245SerTyr: 2.245 ± 1.353
0.0SerXaa: 0.0 ± 0.0
Thr
5.612ThrAla: 5.612 ± 0.98
1.122ThrCys: 1.122 ± 0.677
1.122ThrAsp: 1.122 ± 0.677
2.245ThrGlu: 2.245 ± 0.101
2.245ThrPhe: 2.245 ± 1.353
4.489ThrGly: 4.489 ± 1.252
2.245ThrHis: 2.245 ± 0.101
2.245ThrIle: 2.245 ± 0.101
1.122ThrLys: 1.122 ± 0.677
2.245ThrLeu: 2.245 ± 1.556
0.0ThrMet: 0.0 ± 0.0
1.122ThrAsn: 1.122 ± 0.677
2.245ThrPro: 2.245 ± 0.101
4.489ThrGln: 4.489 ± 1.252
6.734ThrArg: 6.734 ± 1.151
3.367ThrSer: 3.367 ± 2.03
2.245ThrThr: 2.245 ± 0.101
4.489ThrVal: 4.489 ± 0.202
1.122ThrTrp: 1.122 ± 0.778
1.122ThrTyr: 1.122 ± 0.677
0.0ThrXaa: 0.0 ± 0.0
Val
1.122ValAla: 1.122 ± 0.778
0.0ValCys: 0.0 ± 0.0
2.245ValAsp: 2.245 ± 0.101
1.122ValGlu: 1.122 ± 0.778
1.122ValPhe: 1.122 ± 0.778
2.245ValGly: 2.245 ± 1.353
0.0ValHis: 0.0 ± 0.0
4.489ValIle: 4.489 ± 3.112
1.122ValLys: 1.122 ± 0.778
3.367ValLeu: 3.367 ± 2.03
2.245ValMet: 2.245 ± 1.556
0.0ValAsn: 0.0 ± 0.0
5.612ValPro: 5.612 ± 1.929
4.489ValGln: 4.489 ± 1.657
3.367ValArg: 3.367 ± 2.03
6.734ValSer: 6.734 ± 1.151
1.122ValThr: 1.122 ± 0.677
0.0ValVal: 0.0 ± 0.0
1.122ValTrp: 1.122 ± 0.677
2.245ValTyr: 2.245 ± 1.353
0.0ValXaa: 0.0 ± 0.0
Trp
1.122TrpAla: 1.122 ± 0.677
2.245TrpCys: 2.245 ± 1.556
1.122TrpAsp: 1.122 ± 0.778
1.122TrpGlu: 1.122 ± 0.778
1.122TrpPhe: 1.122 ± 0.778
2.245TrpGly: 2.245 ± 0.101
0.0TrpHis: 0.0 ± 0.0
1.122TrpIle: 1.122 ± 0.677
0.0TrpLys: 0.0 ± 0.0
3.367TrpLeu: 3.367 ± 0.576
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.122TrpGln: 1.122 ± 0.778
2.245TrpArg: 2.245 ± 1.556
3.367TrpSer: 3.367 ± 2.03
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.856TyrAla: 7.856 ± 3.991
1.122TyrCys: 1.122 ± 0.778
2.245TyrAsp: 2.245 ± 0.101
4.489TyrGlu: 4.489 ± 1.252
1.122TyrPhe: 1.122 ± 0.778
2.245TyrGly: 2.245 ± 1.353
3.367TyrHis: 3.367 ± 0.576
5.612TyrIle: 5.612 ± 1.929
0.0TyrLys: 0.0 ± 0.0
0.0TyrLeu: 0.0 ± 0.0
1.122TyrMet: 1.122 ± 0.778
0.0TyrAsn: 0.0 ± 0.0
4.489TyrPro: 4.489 ± 1.252
4.489TyrGln: 4.489 ± 1.657
4.489TyrArg: 4.489 ± 0.202
1.122TyrSer: 1.122 ± 0.677
5.612TyrThr: 5.612 ± 3.384
3.367TyrVal: 3.367 ± 2.334
1.122TyrTrp: 1.122 ± 0.677
2.245TyrTyr: 2.245 ± 1.353
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (892 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski