Amino acid dipepetide frequency for Zoogloea oleivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.369AlaAla: 15.369 ± 0.143	1.326AlaCys: 1.326 ± 0.03	6.737AlaAsp: 6.737 ± 0.075	7.353AlaGlu: 7.353 ± 0.077	4.083AlaPhe: 4.083 ± 0.052	10.38AlaGly: 10.38 ± 0.119	2.507AlaHis: 2.507 ± 0.042	5.655AlaIle: 5.655 ± 0.061	3.669AlaLys: 3.669 ± 0.056	13.645AlaLeu: 13.645 ± 0.094	2.962AlaMet: 2.962 ± 0.045	2.99AlaAsn: 2.99 ± 0.046	5.346AlaPro: 5.346 ± 0.074	4.135AlaGln: 4.135 ± 0.047	8.842AlaArg: 8.842 ± 0.092	6.668AlaSer: 6.668 ± 0.071	5.844AlaThr: 5.844 ± 0.087	8.135AlaVal: 8.135 ± 0.073	1.727AlaTrp: 1.727 ± 0.035	2.476AlaTyr: 2.476 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	1.101CysAla: 1.101 ± 0.026	0.159CysCys: 0.159 ± 0.011	0.545CysAsp: 0.545 ± 0.018	0.532CysGlu: 0.532 ± 0.02	0.37CysPhe: 0.37 ± 0.016	0.996CysGly: 0.996 ± 0.03	0.334CysHis: 0.334 ± 0.017	0.438CysIle: 0.438 ± 0.016	0.246CysLys: 0.246 ± 0.014	0.958CysLeu: 0.958 ± 0.026	0.187CysMet: 0.187 ± 0.01	0.27CysAsn: 0.27 ± 0.013	0.553CysPro: 0.553 ± 0.019	0.278CysGln: 0.278 ± 0.012	0.733CysArg: 0.733 ± 0.02	0.584CysSer: 0.584 ± 0.02	0.5CysThr: 0.5 ± 0.019	0.658CysVal: 0.658 ± 0.022	0.134CysTrp: 0.134 ± 0.009	0.236CysTyr: 0.236 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.704AspAla: 6.704 ± 0.067	0.523AspCys: 0.523 ± 0.018	2.938AspAsp: 2.938 ± 0.049	3.495AspGlu: 3.495 ± 0.051	2.304AspPhe: 2.304 ± 0.038	4.902AspGly: 4.902 ± 0.066	1.098AspHis: 1.098 ± 0.028	2.778AspIle: 2.778 ± 0.047	2.069AspLys: 2.069 ± 0.034	5.586AspLeu: 5.586 ± 0.065	1.194AspMet: 1.194 ± 0.028	1.487AspAsn: 1.487 ± 0.031	2.982AspPro: 2.982 ± 0.046	1.692AspGln: 1.692 ± 0.033	3.203AspArg: 3.203 ± 0.051	2.721AspSer: 2.721 ± 0.04	2.755AspThr: 2.755 ± 0.045	4.024AspVal: 4.024 ± 0.055	0.943AspTrp: 0.943 ± 0.025	1.542AspTyr: 1.542 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	7.521GluAla: 7.521 ± 0.077	0.442GluCys: 0.442 ± 0.016	2.567GluAsp: 2.567 ± 0.038	3.053GluGlu: 3.053 ± 0.055	1.845GluPhe: 1.845 ± 0.036	4.007GluGly: 4.007 ± 0.052	1.405GluHis: 1.405 ± 0.032	3.173GluIle: 3.173 ± 0.051	2.381GluLys: 2.381 ± 0.044	6.303GluLeu: 6.303 ± 0.078	1.416GluMet: 1.416 ± 0.032	1.558GluAsn: 1.558 ± 0.038	2.358GluPro: 2.358 ± 0.041	2.602GluGln: 2.602 ± 0.045	4.756GluArg: 4.756 ± 0.053	3.049GluSer: 3.049 ± 0.038	2.942GluThr: 2.942 ± 0.047	4.266GluVal: 4.266 ± 0.055	0.811GluTrp: 0.811 ± 0.02	1.146GluTyr: 1.146 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.199PheAla: 4.199 ± 0.046	0.414PheCys: 0.414 ± 0.019	2.525PheAsp: 2.525 ± 0.043	2.241PheGlu: 2.241 ± 0.037	1.466PhePhe: 1.466 ± 0.034	3.33PheGly: 3.33 ± 0.058	0.813PheHis: 0.813 ± 0.023	1.704PheIle: 1.704 ± 0.036	1.166PheLys: 1.166 ± 0.027	3.293PheLeu: 3.293 ± 0.053	0.797PheMet: 0.797 ± 0.023	1.162PheAsn: 1.162 ± 0.028	1.59PhePro: 1.59 ± 0.033	1.076PheGln: 1.076 ± 0.025	2.23PheArg: 2.23 ± 0.036	2.289PheSer: 2.289 ± 0.036	1.906PheThr: 1.906 ± 0.038	2.788PheVal: 2.788 ± 0.042	0.475PheTrp: 0.475 ± 0.018	0.911PheTyr: 0.911 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	8.054GlyAla: 8.054 ± 0.085	0.972GlyCys: 0.972 ± 0.024	4.122GlyAsp: 4.122 ± 0.054	4.841GlyGlu: 4.841 ± 0.059	3.382GlyPhe: 3.382 ± 0.048	6.63GlyGly: 6.63 ± 0.117	1.886GlyHis: 1.886 ± 0.035	4.277GlyIle: 4.277 ± 0.053	3.673GlyLys: 3.673 ± 0.053	8.995GlyLeu: 8.995 ± 0.088	2.171GlyMet: 2.171 ± 0.035	2.42GlyAsn: 2.42 ± 0.051	2.763GlyPro: 2.763 ± 0.041	3.098GlyGln: 3.098 ± 0.048	5.555GlyArg: 5.555 ± 0.068	4.627GlySer: 4.627 ± 0.071	4.196GlyThr: 4.196 ± 0.085	6.299GlyVal: 6.299 ± 0.076	1.345GlyTrp: 1.345 ± 0.031	2.241GlyTyr: 2.241 ± 0.039	0.002GlyXaa: 0.002 ± 0.001
His	2.588HisAla: 2.588 ± 0.046	0.272HisCys: 0.272 ± 0.015	1.202HisAsp: 1.202 ± 0.027	1.147HisGlu: 1.147 ± 0.03	0.97HisPhe: 0.97 ± 0.023	1.929HisGly: 1.929 ± 0.039	0.685HisHis: 0.685 ± 0.023	1.037HisIle: 1.037 ± 0.024	0.633HisLys: 0.633 ± 0.019	2.506HisLeu: 2.506 ± 0.042	0.453HisMet: 0.453 ± 0.015	0.514HisAsn: 0.514 ± 0.019	1.492HisPro: 1.492 ± 0.035	0.769HisGln: 0.769 ± 0.022	1.533HisArg: 1.533 ± 0.031	1.123HisSer: 1.123 ± 0.026	1.081HisThr: 1.081 ± 0.026	1.517HisVal: 1.517 ± 0.034	0.374HisTrp: 0.374 ± 0.016	0.643HisTyr: 0.643 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	6.091IleAla: 6.091 ± 0.061	0.448IleCys: 0.448 ± 0.018	3.198IleAsp: 3.198 ± 0.04	3.354IleGlu: 3.354 ± 0.047	1.493IlePhe: 1.493 ± 0.03	4.495IleGly: 4.495 ± 0.058	1.121IleHis: 1.121 ± 0.026	1.936IleIle: 1.936 ± 0.037	1.685IleLys: 1.685 ± 0.035	4.295IleLeu: 4.295 ± 0.058	0.74IleMet: 0.74 ± 0.022	1.593IleAsn: 1.593 ± 0.034	2.415IlePro: 2.415 ± 0.035	1.495IleGln: 1.495 ± 0.035	3.251IleArg: 3.251 ± 0.047	2.75IleSer: 2.75 ± 0.047	2.669IleThr: 2.669 ± 0.056	3.719IleVal: 3.719 ± 0.05	0.452IleTrp: 0.452 ± 0.017	1.083IleTyr: 1.083 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.238LysAla: 4.238 ± 0.06	0.222LysCys: 0.222 ± 0.012	1.839LysAsp: 1.839 ± 0.032	1.853LysGlu: 1.853 ± 0.041	0.942LysPhe: 0.942 ± 0.026	2.654LysGly: 2.654 ± 0.045	0.719LysHis: 0.719 ± 0.02	1.694LysIle: 1.694 ± 0.032	1.527LysLys: 1.527 ± 0.039	3.778LysLeu: 3.778 ± 0.051	0.856LysMet: 0.856 ± 0.025	1.066LysAsn: 1.066 ± 0.028	2.221LysPro: 2.221 ± 0.042	1.258LysGln: 1.258 ± 0.028	2.322LysArg: 2.322 ± 0.045	1.951LysSer: 1.951 ± 0.034	1.992LysThr: 1.992 ± 0.039	2.727LysVal: 2.727 ± 0.056	0.372LysTrp: 0.372 ± 0.016	0.723LysTyr: 0.723 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.881LeuAla: 14.881 ± 0.114	1.073LeuCys: 1.073 ± 0.028	6.35LeuAsp: 6.35 ± 0.066	5.886LeuGlu: 5.886 ± 0.064	3.787LeuPhe: 3.787 ± 0.055	8.512LeuGly: 8.512 ± 0.077	2.319LeuHis: 2.319 ± 0.039	5.104LeuIle: 5.104 ± 0.058	3.962LeuLys: 3.962 ± 0.058	11.464LeuLeu: 11.464 ± 0.131	2.372LeuMet: 2.372 ± 0.039	2.892LeuAsn: 2.892 ± 0.043	6.19LeuPro: 6.19 ± 0.071	3.666LeuGln: 3.666 ± 0.048	7.728LeuArg: 7.728 ± 0.081	6.58LeuSer: 6.58 ± 0.064	5.67LeuThr: 5.67 ± 0.065	7.736LeuVal: 7.736 ± 0.078	1.2LeuTrp: 1.2 ± 0.031	2.139LeuTyr: 2.139 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.675MetAla: 2.675 ± 0.042	0.166MetCys: 0.166 ± 0.01	1.164MetAsp: 1.164 ± 0.028	1.143MetGlu: 1.143 ± 0.022	0.644MetPhe: 0.644 ± 0.02	1.604MetGly: 1.604 ± 0.035	0.493MetHis: 0.493 ± 0.018	1.028MetIle: 1.028 ± 0.028	1.005MetLys: 1.005 ± 0.024	2.456MetLeu: 2.456 ± 0.041	0.522MetMet: 0.522 ± 0.018	0.87MetAsn: 0.87 ± 0.023	1.408MetPro: 1.408 ± 0.031	0.911MetGln: 0.911 ± 0.021	1.512MetArg: 1.512 ± 0.032	1.617MetSer: 1.617 ± 0.036	1.417MetThr: 1.417 ± 0.031	1.488MetVal: 1.488 ± 0.027	0.203MetTrp: 0.203 ± 0.011	0.348MetTyr: 0.348 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.22AsnAla: 3.22 ± 0.048	0.296AsnCys: 0.296 ± 0.012	1.452AsnAsp: 1.452 ± 0.037	1.39AsnGlu: 1.39 ± 0.031	0.99AsnPhe: 0.99 ± 0.025	2.373AsnGly: 2.373 ± 0.046	0.548AsnHis: 0.548 ± 0.018	1.36AsnIle: 1.36 ± 0.031	0.91AsnLys: 0.91 ± 0.026	3.027AsnLeu: 3.027 ± 0.048	0.573AsnMet: 0.573 ± 0.019	0.825AsnAsn: 0.825 ± 0.027	1.973AsnPro: 1.973 ± 0.033	0.962AsnGln: 0.962 ± 0.025	1.888AsnArg: 1.888 ± 0.038	1.39AsnSer: 1.39 ± 0.031	1.478AsnThr: 1.478 ± 0.034	1.85AsnVal: 1.85 ± 0.034	0.451AsnTrp: 0.451 ± 0.019	0.724AsnTyr: 0.724 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.692ProAla: 6.692 ± 0.078	0.425ProCys: 0.425 ± 0.017	3.393ProAsp: 3.393 ± 0.046	3.613ProGlu: 3.613 ± 0.047	1.842ProPhe: 1.842 ± 0.039	4.313ProGly: 4.313 ± 0.053	1.019ProHis: 1.019 ± 0.026	2.076ProIle: 2.076 ± 0.033	1.576ProLys: 1.576 ± 0.039	5.233ProLeu: 5.233 ± 0.059	1.115ProMet: 1.115 ± 0.028	1.269ProAsn: 1.269 ± 0.028	2.525ProPro: 2.525 ± 0.049	1.679ProGln: 1.679 ± 0.037	2.876ProArg: 2.876 ± 0.048	2.601ProSer: 2.601 ± 0.039	2.465ProThr: 2.465 ± 0.043	4.334ProVal: 4.334 ± 0.055	0.66ProTrp: 0.66 ± 0.02	1.087ProTyr: 1.087 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	4.819GlnAla: 4.819 ± 0.075	0.29GlnCys: 0.29 ± 0.014	1.564GlnAsp: 1.564 ± 0.035	1.738GlnGlu: 1.738 ± 0.034	1.167GlnPhe: 1.167 ± 0.027	2.57GlnGly: 2.57 ± 0.045	0.849GlnHis: 0.849 ± 0.023	1.864GlnIle: 1.864 ± 0.034	1.179GlnLys: 1.179 ± 0.028	3.899GlnLeu: 3.899 ± 0.045	0.846GlnMet: 0.846 ± 0.02	0.923GlnAsn: 0.923 ± 0.025	1.926GlnPro: 1.926 ± 0.037	1.555GlnGln: 1.555 ± 0.031	2.875GlnArg: 2.875 ± 0.047	1.843GlnSer: 1.843 ± 0.037	1.824GlnThr: 1.824 ± 0.034	2.819GlnVal: 2.819 ± 0.041	0.503GlnTrp: 0.503 ± 0.018	0.7GlnTyr: 0.7 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	7.002ArgAla: 7.002 ± 0.075	0.656ArgCys: 0.656 ± 0.02	3.763ArgAsp: 3.763 ± 0.05	4.257ArgGlu: 4.257 ± 0.056	3.068ArgPhe: 3.068 ± 0.049	4.363ArgGly: 4.363 ± 0.054	1.912ArgHis: 1.912 ± 0.039	3.998ArgIle: 3.998 ± 0.053	2.447ArgLys: 2.447 ± 0.04	8.529ArgLeu: 8.529 ± 0.081	1.735ArgMet: 1.735 ± 0.035	2.054ArgAsn: 2.054 ± 0.034	3.248ArgPro: 3.248 ± 0.056	3.13ArgGln: 3.13 ± 0.049	5.232ArgArg: 5.232 ± 0.078	3.703ArgSer: 3.703 ± 0.054	3.06ArgThr: 3.06 ± 0.04	4.82ArgVal: 4.82 ± 0.062	1.043ArgTrp: 1.043 ± 0.027	1.936ArgTyr: 1.936 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.557SerAla: 6.557 ± 0.082	0.527SerCys: 0.527 ± 0.021	2.883SerAsp: 2.883 ± 0.047	2.819SerGlu: 2.819 ± 0.048	2.151SerPhe: 2.151 ± 0.034	5.482SerGly: 5.482 ± 0.08	1.229SerHis: 1.229 ± 0.027	2.659SerIle: 2.659 ± 0.044	1.64SerLys: 1.64 ± 0.033	6.432SerLeu: 6.432 ± 0.065	1.272SerMet: 1.272 ± 0.024	1.473SerAsn: 1.473 ± 0.032	2.958SerPro: 2.958 ± 0.043	1.8SerGln: 1.8 ± 0.039	3.872SerArg: 3.872 ± 0.052	3.192SerSer: 3.192 ± 0.055	2.981SerThr: 2.981 ± 0.055	4.199SerVal: 4.199 ± 0.056	0.728SerTrp: 0.728 ± 0.021	1.246SerTyr: 1.246 ± 0.031	0.001SerXaa: 0.001 ± 0.001
Thr	5.651ThrAla: 5.651 ± 0.087	0.466ThrCys: 0.466 ± 0.016	2.702ThrAsp: 2.702 ± 0.05	2.68ThrGlu: 2.68 ± 0.044	1.674ThrPhe: 1.674 ± 0.027	4.703ThrGly: 4.703 ± 0.074	1.217ThrHis: 1.217 ± 0.026	2.247ThrIle: 2.247 ± 0.044	1.325ThrLys: 1.325 ± 0.036	6.579ThrLeu: 6.579 ± 0.082	0.906ThrMet: 0.906 ± 0.024	1.283ThrAsn: 1.283 ± 0.033	3.417ThrPro: 3.417 ± 0.048	1.723ThrGln: 1.723 ± 0.033	3.616ThrArg: 3.616 ± 0.047	2.695ThrSer: 2.695 ± 0.067	2.896ThrThr: 2.896 ± 0.068	4.019ThrVal: 4.019 ± 0.064	0.653ThrTrp: 0.653 ± 0.022	1.194ThrTyr: 1.194 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	8.813ValAla: 8.813 ± 0.093	0.742ValCys: 0.742 ± 0.023	4.194ValAsp: 4.194 ± 0.053	4.519ValGlu: 4.519 ± 0.055	2.737ValPhe: 2.737 ± 0.042	5.539ValGly: 5.539 ± 0.072	1.448ValHis: 1.448 ± 0.033	3.678ValIle: 3.678 ± 0.05	2.618ValLys: 2.618 ± 0.048	7.979ValLeu: 7.979 ± 0.084	1.797ValMet: 1.797 ± 0.033	1.969ValAsn: 1.969 ± 0.036	3.628ValPro: 3.628 ± 0.048	2.366ValGln: 2.366 ± 0.035	4.894ValArg: 4.894 ± 0.055	4.666ValSer: 4.666 ± 0.064	4.121ValThr: 4.121 ± 0.065	5.928ValVal: 5.928 ± 0.085	0.934ValTrp: 0.934 ± 0.026	1.344ValTyr: 1.344 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.209TrpAla: 1.209 ± 0.027	0.15TrpCys: 0.15 ± 0.01	0.596TrpAsp: 0.596 ± 0.019	0.619TrpGlu: 0.619 ± 0.022	0.52TrpPhe: 0.52 ± 0.019	0.819TrpGly: 0.819 ± 0.026	0.37TrpHis: 0.37 ± 0.014	0.709TrpIle: 0.709 ± 0.022	0.513TrpLys: 0.513 ± 0.017	2.011TrpLeu: 2.011 ± 0.042	0.343TrpMet: 0.343 ± 0.016	0.423TrpAsn: 0.423 ± 0.017	0.618TrpPro: 0.618 ± 0.021	0.688TrpGln: 0.688 ± 0.024	1.13TrpArg: 1.13 ± 0.029	0.773TrpSer: 0.773 ± 0.023	0.665TrpThr: 0.665 ± 0.021	0.918TrpVal: 0.918 ± 0.027	0.235TrpTrp: 0.235 ± 0.013	0.272TrpTyr: 0.272 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.465TyrAla: 2.465 ± 0.039	0.245TyrCys: 0.245 ± 0.011	1.206TyrAsp: 1.206 ± 0.032	1.072TyrGlu: 1.072 ± 0.028	0.939TyrPhe: 0.939 ± 0.025	1.944TyrGly: 1.944 ± 0.035	0.496TyrHis: 0.496 ± 0.018	0.87TyrIle: 0.87 ± 0.02	0.727TyrLys: 0.727 ± 0.023	2.542TyrLeu: 2.542 ± 0.039	0.417TyrMet: 0.417 ± 0.016	0.64TyrAsn: 0.64 ± 0.022	1.182TyrPro: 1.182 ± 0.031	0.869TyrGln: 0.869 ± 0.022	1.908TyrArg: 1.908 ± 0.036	1.28TyrSer: 1.28 ± 0.032	1.185TyrThr: 1.185 ± 0.027	1.669TyrVal: 1.669 ± 0.034	0.334TyrTrp: 0.334 ± 0.015	0.569TyrTyr: 0.569 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4972 proteins (1663900 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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