Amino acid dipepetide frequency for Fengkai orbivirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.812AlaAla: 6.812 ± 1.917
0.973AlaCys: 0.973 ± 0.587
4.379AlaAsp: 4.379 ± 0.471
6.001AlaGlu: 6.001 ± 1.104
1.622AlaPhe: 1.622 ± 0.384
3.244AlaGly: 3.244 ± 0.612
1.135AlaHis: 1.135 ± 0.524
5.676AlaIle: 5.676 ± 1.278
3.406AlaLys: 3.406 ± 0.854
6.325AlaLeu: 6.325 ± 1.495
2.271AlaMet: 2.271 ± 0.375
1.46AlaAsn: 1.46 ± 0.569
2.757AlaPro: 2.757 ± 0.422
3.244AlaGln: 3.244 ± 0.523
6.325AlaArg: 6.325 ± 0.965
3.244AlaSer: 3.244 ± 0.612
3.568AlaThr: 3.568 ± 0.708
5.514AlaVal: 5.514 ± 0.586
1.135AlaTrp: 1.135 ± 0.409
3.892AlaTyr: 3.892 ± 0.666
0.0AlaXaa: 0.0 ± 0.0
Cys
0.973CysAla: 0.973 ± 0.284
0.324CysCys: 0.324 ± 0.163
0.487CysAsp: 0.487 ± 0.185
0.162CysGlu: 0.162 ± 0.149
0.811CysPhe: 0.811 ± 0.427
0.973CysGly: 0.973 ± 0.287
0.0CysHis: 0.0 ± 0.0
0.649CysIle: 0.649 ± 0.333
0.162CysLys: 0.162 ± 0.131
0.811CysLeu: 0.811 ± 0.5
0.162CysMet: 0.162 ± 0.124
0.973CysAsn: 0.973 ± 0.506
0.162CysPro: 0.162 ± 0.149
0.487CysGln: 0.487 ± 0.322
0.324CysArg: 0.324 ± 0.199
0.973CysSer: 0.973 ± 0.415
0.649CysThr: 0.649 ± 0.355
0.487CysVal: 0.487 ± 0.32
0.0CysTrp: 0.0 ± 0.0
0.487CysTyr: 0.487 ± 0.35
0.0CysXaa: 0.0 ± 0.0
Asp
3.73AspAla: 3.73 ± 0.891
0.487AspCys: 0.487 ± 0.204
3.568AspAsp: 3.568 ± 0.469
5.514AspGlu: 5.514 ± 0.858
2.757AspPhe: 2.757 ± 0.667
3.568AspGly: 3.568 ± 0.586
1.622AspHis: 1.622 ± 0.461
3.081AspIle: 3.081 ± 0.716
2.757AspLys: 2.757 ± 0.702
6.487AspLeu: 6.487 ± 1.201
1.784AspMet: 1.784 ± 0.632
0.811AspAsn: 0.811 ± 0.26
2.108AspPro: 2.108 ± 0.55
1.946AspGln: 1.946 ± 0.309
3.892AspArg: 3.892 ± 0.985
3.081AspSer: 3.081 ± 0.353
2.595AspThr: 2.595 ± 0.56
7.298AspVal: 7.298 ± 0.591
0.324AspTrp: 0.324 ± 0.212
1.784AspTyr: 1.784 ± 0.582
0.0AspXaa: 0.0 ± 0.0
Glu
5.676GluAla: 5.676 ± 1.196
0.649GluCys: 0.649 ± 0.466
3.244GluAsp: 3.244 ± 0.502
8.271GluGlu: 8.271 ± 1.778
2.433GluPhe: 2.433 ± 0.711
3.244GluGly: 3.244 ± 0.46
1.135GluHis: 1.135 ± 0.344
5.352GluIle: 5.352 ± 0.822
4.541GluLys: 4.541 ± 1.422
6.812GluLeu: 6.812 ± 0.682
2.919GluMet: 2.919 ± 0.686
1.946GluAsn: 1.946 ± 0.553
3.244GluPro: 3.244 ± 0.721
2.595GluGln: 2.595 ± 0.588
5.352GluArg: 5.352 ± 0.851
4.541GluSer: 4.541 ± 1.222
3.892GluThr: 3.892 ± 0.772
5.676GluVal: 5.676 ± 1.416
1.622GluTrp: 1.622 ± 0.49
1.946GluTyr: 1.946 ± 0.699
0.0GluXaa: 0.0 ± 0.0
Phe
2.433PheAla: 2.433 ± 0.3
0.649PheCys: 0.649 ± 0.419
2.271PheAsp: 2.271 ± 0.66
1.946PheGlu: 1.946 ± 0.608
1.135PhePhe: 1.135 ± 0.403
2.433PheGly: 2.433 ± 0.642
0.973PheHis: 0.973 ± 0.277
2.108PheIle: 2.108 ± 0.501
2.757PheLys: 2.757 ± 0.529
3.244PheLeu: 3.244 ± 0.614
0.649PheMet: 0.649 ± 0.394
0.811PheAsn: 0.811 ± 0.422
0.811PhePro: 0.811 ± 0.205
2.271PheGln: 2.271 ± 0.504
3.081PheArg: 3.081 ± 0.749
3.081PheSer: 3.081 ± 0.473
1.946PheThr: 1.946 ± 0.456
1.622PheVal: 1.622 ± 0.571
0.649PheTrp: 0.649 ± 0.449
1.297PheTyr: 1.297 ± 0.4
0.0PheXaa: 0.0 ± 0.0
Gly
4.217GlyAla: 4.217 ± 1.112
0.487GlyCys: 0.487 ± 0.286
4.541GlyAsp: 4.541 ± 0.788
3.892GlyGlu: 3.892 ± 0.533
2.271GlyPhe: 2.271 ± 0.475
3.568GlyGly: 3.568 ± 0.904
0.811GlyHis: 0.811 ± 0.334
3.73GlyIle: 3.73 ± 0.787
4.379GlyLys: 4.379 ± 1.18
4.541GlyLeu: 4.541 ± 0.858
2.595GlyMet: 2.595 ± 0.878
1.946GlyAsn: 1.946 ± 0.51
1.784GlyPro: 1.784 ± 0.457
1.46GlyGln: 1.46 ± 0.428
4.054GlyArg: 4.054 ± 0.816
3.73GlySer: 3.73 ± 0.649
3.244GlyThr: 3.244 ± 0.81
5.514GlyVal: 5.514 ± 0.604
0.649GlyTrp: 0.649 ± 0.319
2.108GlyTyr: 2.108 ± 0.771
0.0GlyXaa: 0.0 ± 0.0
His
2.271HisAla: 2.271 ± 0.406
0.0HisCys: 0.0 ± 0.0
1.46HisAsp: 1.46 ± 0.453
0.811HisGlu: 0.811 ± 0.395
0.487HisPhe: 0.487 ± 0.313
0.973HisGly: 0.973 ± 0.443
0.487HisHis: 0.487 ± 0.432
1.297HisIle: 1.297 ± 0.671
2.108HisLys: 2.108 ± 0.529
2.595HisLeu: 2.595 ± 0.485
1.135HisMet: 1.135 ± 0.47
0.811HisAsn: 0.811 ± 0.253
1.135HisPro: 1.135 ± 0.394
0.649HisGln: 0.649 ± 0.264
1.784HisArg: 1.784 ± 0.698
1.297HisSer: 1.297 ± 0.164
0.973HisThr: 0.973 ± 0.32
2.595HisVal: 2.595 ± 0.531
0.162HisTrp: 0.162 ± 0.216
1.135HisTyr: 1.135 ± 0.32
0.0HisXaa: 0.0 ± 0.0
Ile
6.163IleAla: 6.163 ± 0.676
0.649IleCys: 0.649 ± 0.304
4.217IleAsp: 4.217 ± 0.994
4.541IleGlu: 4.541 ± 0.385
2.433IlePhe: 2.433 ± 0.613
3.081IleGly: 3.081 ± 0.866
1.784IleHis: 1.784 ± 0.605
4.541IleIle: 4.541 ± 1.218
4.541IleLys: 4.541 ± 0.717
5.676IleLeu: 5.676 ± 0.991
2.757IleMet: 2.757 ± 0.509
2.757IleAsn: 2.757 ± 0.409
2.595IlePro: 2.595 ± 0.793
2.271IleGln: 2.271 ± 0.781
3.081IleArg: 3.081 ± 0.608
3.406IleSer: 3.406 ± 0.727
3.892IleThr: 3.892 ± 0.955
3.892IleVal: 3.892 ± 0.663
1.784IleTrp: 1.784 ± 0.686
3.081IleTyr: 3.081 ± 0.484
0.0IleXaa: 0.0 ± 0.0
Lys
4.054LysAla: 4.054 ± 0.794
0.487LysCys: 0.487 ± 0.286
3.892LysAsp: 3.892 ± 1.025
6.974LysGlu: 6.974 ± 2.598
2.271LysPhe: 2.271 ± 0.514
3.73LysGly: 3.73 ± 0.78
2.108LysHis: 2.108 ± 0.641
5.838LysIle: 5.838 ± 1.253
6.487LysLys: 6.487 ± 1.127
5.19LysLeu: 5.19 ± 0.694
2.919LysMet: 2.919 ± 0.691
2.271LysAsn: 2.271 ± 0.458
1.946LysPro: 1.946 ± 0.59
1.622LysGln: 1.622 ± 0.446
3.892LysArg: 3.892 ± 0.459
1.784LysSer: 1.784 ± 0.723
2.919LysThr: 2.919 ± 0.578
4.217LysVal: 4.217 ± 0.587
0.811LysTrp: 0.811 ± 0.242
1.946LysTyr: 1.946 ± 0.818
0.0LysXaa: 0.0 ± 0.0
Leu
4.865LeuAla: 4.865 ± 0.715
1.297LeuCys: 1.297 ± 0.352
5.028LeuAsp: 5.028 ± 1.193
5.19LeuGlu: 5.19 ± 1.149
2.433LeuPhe: 2.433 ± 0.516
4.541LeuGly: 4.541 ± 1.219
2.433LeuHis: 2.433 ± 0.434
5.19LeuIle: 5.19 ± 1.097
4.865LeuLys: 4.865 ± 0.761
4.541LeuLeu: 4.541 ± 0.84
3.892LeuMet: 3.892 ± 0.495
3.568LeuAsn: 3.568 ± 0.387
5.514LeuPro: 5.514 ± 1.133
3.406LeuGln: 3.406 ± 1.05
7.785LeuArg: 7.785 ± 1.71
7.947LeuSer: 7.947 ± 1.229
4.379LeuThr: 4.379 ± 0.695
5.352LeuVal: 5.352 ± 0.799
0.973LeuTrp: 0.973 ± 0.32
3.406LeuTyr: 3.406 ± 0.884
0.0LeuXaa: 0.0 ± 0.0
Met
2.919MetAla: 2.919 ± 0.425
0.649MetCys: 0.649 ± 0.266
2.108MetAsp: 2.108 ± 0.454
2.433MetGlu: 2.433 ± 0.707
0.973MetPhe: 0.973 ± 0.319
1.622MetGly: 1.622 ± 0.467
1.297MetHis: 1.297 ± 0.403
2.433MetIle: 2.433 ± 0.633
2.108MetLys: 2.108 ± 0.429
5.352MetLeu: 5.352 ± 1.084
1.946MetMet: 1.946 ± 0.442
0.973MetAsn: 0.973 ± 0.259
1.784MetPro: 1.784 ± 0.617
1.784MetGln: 1.784 ± 0.503
2.433MetArg: 2.433 ± 0.604
2.919MetSer: 2.919 ± 0.675
1.622MetThr: 1.622 ± 0.309
2.271MetVal: 2.271 ± 0.291
0.487MetTrp: 0.487 ± 0.236
0.811MetTyr: 0.811 ± 0.457
0.0MetXaa: 0.0 ± 0.0
Asn
1.297AsnAla: 1.297 ± 0.226
0.162AsnCys: 0.162 ± 0.148
2.757AsnAsp: 2.757 ± 0.672
2.757AsnGlu: 2.757 ± 0.709
1.46AsnPhe: 1.46 ± 0.452
3.244AsnGly: 3.244 ± 0.683
0.487AsnHis: 0.487 ± 0.197
2.757AsnIle: 2.757 ± 0.505
1.135AsnLys: 1.135 ± 0.344
2.271AsnLeu: 2.271 ± 0.503
1.784AsnMet: 1.784 ± 0.495
0.487AsnAsn: 0.487 ± 0.185
1.784AsnPro: 1.784 ± 0.509
1.46AsnGln: 1.46 ± 0.238
1.46AsnArg: 1.46 ± 0.456
2.108AsnSer: 2.108 ± 0.585
1.622AsnThr: 1.622 ± 0.474
3.568AsnVal: 3.568 ± 0.793
0.487AsnTrp: 0.487 ± 0.398
0.487AsnTyr: 0.487 ± 0.249
0.0AsnXaa: 0.0 ± 0.0
Pro
1.946ProAla: 1.946 ± 0.374
0.324ProCys: 0.324 ± 0.209
2.757ProAsp: 2.757 ± 0.679
2.271ProGlu: 2.271 ± 0.63
2.108ProPhe: 2.108 ± 0.41
2.271ProGly: 2.271 ± 0.476
0.811ProHis: 0.811 ± 0.284
4.217ProIle: 4.217 ± 1.119
2.433ProLys: 2.433 ± 0.732
2.595ProLeu: 2.595 ± 0.773
1.46ProMet: 1.46 ± 0.43
1.297ProAsn: 1.297 ± 0.349
2.108ProPro: 2.108 ± 0.627
1.784ProGln: 1.784 ± 0.422
2.108ProArg: 2.108 ± 0.388
0.811ProSer: 0.811 ± 0.42
3.568ProThr: 3.568 ± 1.191
2.108ProVal: 2.108 ± 0.275
0.324ProTrp: 0.324 ± 0.261
1.297ProTyr: 1.297 ± 0.429
0.0ProXaa: 0.0 ± 0.0
Gln
2.595GlnAla: 2.595 ± 0.76
0.162GlnCys: 0.162 ± 0.169
1.135GlnAsp: 1.135 ± 0.369
2.433GlnGlu: 2.433 ± 0.724
1.784GlnPhe: 1.784 ± 0.429
3.406GlnGly: 3.406 ± 1.018
1.297GlnHis: 1.297 ± 0.468
3.892GlnIle: 3.892 ± 0.724
3.406GlnLys: 3.406 ± 0.771
2.919GlnLeu: 2.919 ± 0.649
0.973GlnMet: 0.973 ± 0.419
1.297GlnAsn: 1.297 ± 0.24
1.46GlnPro: 1.46 ± 0.585
0.649GlnGln: 0.649 ± 0.446
2.271GlnArg: 2.271 ± 0.454
2.108GlnSer: 2.108 ± 0.484
2.271GlnThr: 2.271 ± 0.19
1.46GlnVal: 1.46 ± 0.357
0.324GlnTrp: 0.324 ± 0.212
1.622GlnTyr: 1.622 ± 0.528
0.0GlnXaa: 0.0 ± 0.0
Arg
5.19ArgAla: 5.19 ± 1.418
0.811ArgCys: 0.811 ± 0.285
3.73ArgAsp: 3.73 ± 0.692
5.19ArgGlu: 5.19 ± 0.7
3.244ArgPhe: 3.244 ± 0.63
4.865ArgGly: 4.865 ± 0.897
1.135ArgHis: 1.135 ± 0.38
4.217ArgIle: 4.217 ± 0.599
4.379ArgLys: 4.379 ± 0.914
5.676ArgLeu: 5.676 ± 1.372
2.595ArgMet: 2.595 ± 0.661
2.919ArgAsn: 2.919 ± 0.324
2.108ArgPro: 2.108 ± 0.439
2.433ArgGln: 2.433 ± 0.721
4.054ArgArg: 4.054 ± 0.466
2.595ArgSer: 2.595 ± 0.715
3.73ArgThr: 3.73 ± 0.706
3.892ArgVal: 3.892 ± 0.702
0.487ArgTrp: 0.487 ± 0.279
1.784ArgTyr: 1.784 ± 0.602
0.0ArgXaa: 0.0 ± 0.0
Ser
4.703SerAla: 4.703 ± 0.722
0.162SerCys: 0.162 ± 0.169
3.406SerAsp: 3.406 ± 0.468
5.028SerGlu: 5.028 ± 0.554
1.784SerPhe: 1.784 ± 0.45
4.541SerGly: 4.541 ± 0.761
1.946SerHis: 1.946 ± 0.464
2.433SerIle: 2.433 ± 0.523
4.054SerLys: 4.054 ± 1.08
4.379SerLeu: 4.379 ± 0.545
1.946SerMet: 1.946 ± 0.573
1.784SerAsn: 1.784 ± 0.462
1.946SerPro: 1.946 ± 0.382
2.271SerGln: 2.271 ± 0.465
2.919SerArg: 2.919 ± 0.906
3.081SerSer: 3.081 ± 0.959
3.244SerThr: 3.244 ± 0.953
3.406SerVal: 3.406 ± 0.748
1.297SerTrp: 1.297 ± 0.5
2.108SerTyr: 2.108 ± 0.78
0.0SerXaa: 0.0 ± 0.0
Thr
4.379ThrAla: 4.379 ± 0.785
0.324ThrCys: 0.324 ± 0.214
2.757ThrAsp: 2.757 ± 0.406
2.757ThrGlu: 2.757 ± 0.826
2.108ThrPhe: 2.108 ± 0.422
3.406ThrGly: 3.406 ± 0.735
1.297ThrHis: 1.297 ± 0.608
3.406ThrIle: 3.406 ± 0.665
4.379ThrLys: 4.379 ± 0.684
5.838ThrLeu: 5.838 ± 1.402
2.108ThrMet: 2.108 ± 0.631
1.46ThrAsn: 1.46 ± 0.446
1.135ThrPro: 1.135 ± 0.371
2.595ThrGln: 2.595 ± 0.503
2.271ThrArg: 2.271 ± 0.478
3.081ThrSer: 3.081 ± 0.685
3.244ThrThr: 3.244 ± 0.835
2.433ThrVal: 2.433 ± 0.77
0.487ThrTrp: 0.487 ± 0.358
2.919ThrTyr: 2.919 ± 1.372
0.0ThrXaa: 0.0 ± 0.0
Val
5.352ValAla: 5.352 ± 1.068
0.811ValCys: 0.811 ± 0.509
3.568ValAsp: 3.568 ± 1.157
5.352ValGlu: 5.352 ± 0.821
2.271ValPhe: 2.271 ± 0.46
3.892ValGly: 3.892 ± 0.512
1.622ValHis: 1.622 ± 0.493
3.244ValIle: 3.244 ± 0.828
3.73ValLys: 3.73 ± 0.937
6.487ValLeu: 6.487 ± 0.981
3.73ValMet: 3.73 ± 1.065
2.595ValAsn: 2.595 ± 0.674
2.433ValPro: 2.433 ± 0.69
3.081ValGln: 3.081 ± 0.624
5.514ValArg: 5.514 ± 1.173
4.217ValSer: 4.217 ± 0.572
3.081ValThr: 3.081 ± 0.397
3.892ValVal: 3.892 ± 0.868
0.811ValTrp: 0.811 ± 0.397
3.73ValTyr: 3.73 ± 0.448
0.0ValXaa: 0.0 ± 0.0
Trp
0.649TrpAla: 0.649 ± 0.294
0.324TrpCys: 0.324 ± 0.179
0.973TrpAsp: 0.973 ± 0.389
0.811TrpGlu: 0.811 ± 0.462
0.649TrpPhe: 0.649 ± 0.228
0.649TrpGly: 0.649 ± 0.224
0.973TrpHis: 0.973 ± 0.344
0.811TrpIle: 0.811 ± 0.415
1.297TrpLys: 1.297 ± 0.284
1.297TrpLeu: 1.297 ± 0.571
0.324TrpMet: 0.324 ± 0.185
1.135TrpAsn: 1.135 ± 0.356
0.0TrpPro: 0.0 ± 0.0
0.487TrpGln: 0.487 ± 0.246
0.162TrpArg: 0.162 ± 0.175
0.649TrpSer: 0.649 ± 0.336
0.324TrpThr: 0.324 ± 0.209
0.649TrpVal: 0.649 ± 0.245
0.162TrpTrp: 0.162 ± 0.148
0.649TrpTyr: 0.649 ± 0.269
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.757TyrAla: 2.757 ± 0.429
0.324TyrCys: 0.324 ± 0.199
2.919TyrAsp: 2.919 ± 0.818
2.757TyrGlu: 2.757 ± 0.425
1.135TyrPhe: 1.135 ± 0.436
2.271TyrGly: 2.271 ± 0.427
0.811TyrHis: 0.811 ± 0.191
2.271TyrIle: 2.271 ± 0.54
2.433TyrLys: 2.433 ± 0.862
3.568TyrLeu: 3.568 ± 0.933
0.811TyrMet: 0.811 ± 0.251
2.271TyrAsn: 2.271 ± 0.535
1.784TyrPro: 1.784 ± 0.65
0.973TyrGln: 0.973 ± 0.281
2.271TyrArg: 2.271 ± 0.632
1.784TyrSer: 1.784 ± 0.505
1.784TyrThr: 1.784 ± 0.574
3.568TyrVal: 3.568 ± 0.851
0.0TyrTrp: 0.0 ± 0.0
2.433TyrTyr: 2.433 ± 0.564
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (6167 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski