Amino acid dipepetide frequency for Sphingorhabdus soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.167AlaAla: 19.167 ± 0.255	1.053AlaCys: 1.053 ± 0.038	8.278AlaAsp: 8.278 ± 0.114	7.082AlaGlu: 7.082 ± 0.12	4.274AlaPhe: 4.274 ± 0.09	11.404AlaGly: 11.404 ± 0.141	2.43AlaHis: 2.43 ± 0.061	7.933AlaIle: 7.933 ± 0.123	4.946AlaLys: 4.946 ± 0.104	14.024AlaLeu: 14.024 ± 0.178	4.19AlaMet: 4.19 ± 0.091	3.466AlaAsn: 3.466 ± 0.078	6.342AlaPro: 6.342 ± 0.124	4.46AlaGln: 4.46 ± 0.083	10.044AlaArg: 10.044 ± 0.141	7.146AlaSer: 7.146 ± 0.111	7.064AlaThr: 7.064 ± 0.114	8.335AlaVal: 8.335 ± 0.12	1.652AlaTrp: 1.652 ± 0.054	2.62AlaTyr: 2.62 ± 0.06	0.0AlaXaa: 0.0 ± 0.0
Cys	1.023CysAla: 1.023 ± 0.035	0.094CysCys: 0.094 ± 0.012	0.622CysAsp: 0.622 ± 0.03	0.406CysGlu: 0.406 ± 0.024	0.271CysPhe: 0.271 ± 0.019	0.86CysGly: 0.86 ± 0.038	0.192CysHis: 0.192 ± 0.017	0.372CysIle: 0.372 ± 0.025	0.197CysLys: 0.197 ± 0.016	0.627CysLeu: 0.627 ± 0.028	0.122CysMet: 0.122 ± 0.013	0.213CysAsn: 0.213 ± 0.017	0.424CysPro: 0.424 ± 0.027	0.197CysGln: 0.197 ± 0.017	0.545CysArg: 0.545 ± 0.027	0.436CysSer: 0.436 ± 0.023	0.398CysThr: 0.398 ± 0.021	0.551CysVal: 0.551 ± 0.028	0.092CysTrp: 0.092 ± 0.012	0.168CysTyr: 0.168 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	9.071AspAla: 9.071 ± 0.124	0.523AspCys: 0.523 ± 0.028	4.429AspAsp: 4.429 ± 0.098	3.743AspGlu: 3.743 ± 0.085	2.334AspPhe: 2.334 ± 0.058	6.105AspGly: 6.105 ± 0.1	1.422AspHis: 1.422 ± 0.045	3.426AspIle: 3.426 ± 0.071	1.905AspLys: 1.905 ± 0.05	5.871AspLeu: 5.871 ± 0.085	1.536AspMet: 1.536 ± 0.053	1.518AspAsn: 1.518 ± 0.045	3.902AspPro: 3.902 ± 0.074	1.835AspGln: 1.835 ± 0.053	5.142AspArg: 5.142 ± 0.105	2.822AspSer: 2.822 ± 0.066	3.058AspThr: 3.058 ± 0.061	4.172AspVal: 4.172 ± 0.074	1.14AspTrp: 1.14 ± 0.04	1.803AspTyr: 1.803 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	7.426GluAla: 7.426 ± 0.113	0.333GluCys: 0.333 ± 0.021	2.763GluAsp: 2.763 ± 0.067	2.552GluGlu: 2.552 ± 0.071	1.595GluPhe: 1.595 ± 0.047	4.115GluGly: 4.115 ± 0.078	1.091GluHis: 1.091 ± 0.037	3.098GluIle: 3.098 ± 0.06	1.868GluLys: 1.868 ± 0.058	4.834GluLeu: 4.834 ± 0.084	1.473GluMet: 1.473 ± 0.047	1.403GluAsn: 1.403 ± 0.044	2.364GluPro: 2.364 ± 0.054	1.92GluGln: 1.92 ± 0.057	4.808GluArg: 4.808 ± 0.087	2.276GluSer: 2.276 ± 0.06	3.31GluThr: 3.31 ± 0.064	3.34GluVal: 3.34 ± 0.073	0.659GluTrp: 0.659 ± 0.028	1.001GluTyr: 1.001 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	5.212PheAla: 5.212 ± 0.089	0.282PheCys: 0.282 ± 0.019	2.849PheAsp: 2.849 ± 0.06	1.895PheGlu: 1.895 ± 0.055	1.189PhePhe: 1.189 ± 0.049	3.561PheGly: 3.561 ± 0.08	0.657PheHis: 0.657 ± 0.025	1.535PheIle: 1.535 ± 0.048	0.881PheLys: 0.881 ± 0.031	2.766PheLeu: 2.766 ± 0.075	0.69PheMet: 0.69 ± 0.029	0.95PheAsn: 0.95 ± 0.039	1.358PhePro: 1.358 ± 0.041	0.768PheGln: 0.768 ± 0.035	1.98PheArg: 1.98 ± 0.057	1.93PheSer: 1.93 ± 0.047	1.953PheThr: 1.953 ± 0.05	2.695PheVal: 2.695 ± 0.063	0.462PheTrp: 0.462 ± 0.029	0.892PheTyr: 0.892 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	9.817GlyAla: 9.817 ± 0.126	0.892GlyCys: 0.892 ± 0.036	5.819GlyAsp: 5.819 ± 0.094	5.129GlyGlu: 5.129 ± 0.087	3.416GlyPhe: 3.416 ± 0.07	8.096GlyGly: 8.096 ± 0.135	1.937GlyHis: 1.937 ± 0.057	4.825GlyIle: 4.825 ± 0.083	3.457GlyLys: 3.457 ± 0.067	8.368GlyLeu: 8.368 ± 0.118	2.209GlyMet: 2.209 ± 0.057	2.394GlyAsn: 2.394 ± 0.08	3.534GlyPro: 3.534 ± 0.062	2.939GlyGln: 2.939 ± 0.066	6.06GlyArg: 6.06 ± 0.103	5.153GlySer: 5.153 ± 0.088	4.673GlyThr: 4.673 ± 0.087	5.865GlyVal: 5.865 ± 0.1	1.55GlyTrp: 1.55 ± 0.047	2.329GlyTyr: 2.329 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.371HisAla: 2.371 ± 0.061	0.213HisCys: 0.213 ± 0.018	1.399HisAsp: 1.399 ± 0.047	1.025HisGlu: 1.025 ± 0.038	0.772HisPhe: 0.772 ± 0.032	1.98HisGly: 1.98 ± 0.054	0.53HisHis: 0.53 ± 0.028	0.959HisIle: 0.959 ± 0.035	0.465HisLys: 0.465 ± 0.025	1.664HisLeu: 1.664 ± 0.05	0.405HisMet: 0.405 ± 0.023	0.478HisAsn: 0.478 ± 0.027	1.259HisPro: 1.259 ± 0.043	0.501HisGln: 0.501 ± 0.024	1.499HisArg: 1.499 ± 0.047	0.987HisSer: 0.987 ± 0.04	0.682HisThr: 0.682 ± 0.032	1.43HisVal: 1.43 ± 0.04	0.351HisTrp: 0.351 ± 0.022	0.551HisTyr: 0.551 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	9.226IleAla: 9.226 ± 0.127	0.45IleCys: 0.45 ± 0.024	4.83IleAsp: 4.83 ± 0.083	3.73IleGlu: 3.73 ± 0.057	1.711IlePhe: 1.711 ± 0.053	5.421IleGly: 5.421 ± 0.093	0.89IleHis: 0.89 ± 0.032	2.32IleIle: 2.32 ± 0.062	1.439IleLys: 1.439 ± 0.041	3.984IleLeu: 3.984 ± 0.08	0.921IleMet: 0.921 ± 0.038	1.298IleAsn: 1.298 ± 0.038	2.204IlePro: 2.204 ± 0.06	1.1IleGln: 1.1 ± 0.038	2.954IleArg: 2.954 ± 0.057	2.612IleSer: 2.612 ± 0.063	2.494IleThr: 2.494 ± 0.064	5.009IleVal: 5.009 ± 0.103	0.608IleTrp: 0.608 ± 0.028	1.026IleTyr: 1.026 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.29LysAla: 4.29 ± 0.084	0.188LysCys: 0.188 ± 0.015	1.772LysAsp: 1.772 ± 0.054	1.162LysGlu: 1.162 ± 0.046	0.939LysPhe: 0.939 ± 0.032	2.731LysGly: 2.731 ± 0.062	0.551LysHis: 0.551 ± 0.023	1.736LysIle: 1.736 ± 0.051	1.308LysLys: 1.308 ± 0.059	3.161LysLeu: 3.161 ± 0.059	0.848LysMet: 0.848 ± 0.036	0.724LysAsn: 0.724 ± 0.033	1.979LysPro: 1.979 ± 0.061	1.042LysGln: 1.042 ± 0.041	2.416LysArg: 2.416 ± 0.07	1.873LysSer: 1.873 ± 0.053	1.935LysThr: 1.935 ± 0.057	2.171LysVal: 2.171 ± 0.058	0.378LysTrp: 0.378 ± 0.023	0.632LysTyr: 0.632 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	14.501LeuAla: 14.501 ± 0.178	0.718LeuCys: 0.718 ± 0.032	6.39LeuAsp: 6.39 ± 0.089	4.374LeuGlu: 4.374 ± 0.088	3.325LeuPhe: 3.325 ± 0.079	8.151LeuGly: 8.151 ± 0.121	1.64LeuHis: 1.64 ± 0.048	4.947LeuIle: 4.947 ± 0.097	3.03LeuLys: 3.03 ± 0.07	8.703LeuLeu: 8.703 ± 0.154	2.013LeuMet: 2.013 ± 0.051	2.29LeuAsn: 2.29 ± 0.058	5.198LeuPro: 5.198 ± 0.079	2.063LeuGln: 2.063 ± 0.059	6.225LeuArg: 6.225 ± 0.1	5.777LeuSer: 5.777 ± 0.094	5.377LeuThr: 5.377 ± 0.086	7.451LeuVal: 7.451 ± 0.108	1.204LeuTrp: 1.204 ± 0.049	1.87LeuTyr: 1.87 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	3.352MetAla: 3.352 ± 0.068	0.153MetCys: 0.153 ± 0.013	1.03MetAsp: 1.03 ± 0.041	0.885MetGlu: 0.885 ± 0.031	0.707MetPhe: 0.707 ± 0.031	1.852MetGly: 1.852 ± 0.048	0.41MetHis: 0.41 ± 0.023	1.608MetIle: 1.608 ± 0.047	1.001MetLys: 1.001 ± 0.036	2.571MetLeu: 2.571 ± 0.059	0.608MetMet: 0.608 ± 0.029	0.689MetAsn: 0.689 ± 0.031	1.413MetPro: 1.413 ± 0.044	0.682MetGln: 0.682 ± 0.027	1.789MetArg: 1.789 ± 0.052	1.364MetSer: 1.364 ± 0.04	2.005MetThr: 2.005 ± 0.053	1.573MetVal: 1.573 ± 0.047	0.194MetTrp: 0.194 ± 0.019	0.273MetTyr: 0.273 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.36AsnAla: 3.36 ± 0.074	0.219AsnCys: 0.219 ± 0.017	1.564AsnAsp: 1.564 ± 0.047	1.15AsnGlu: 1.15 ± 0.042	0.972AsnPhe: 0.972 ± 0.04	2.443AsnGly: 2.443 ± 0.087	0.477AsnHis: 0.477 ± 0.027	1.41AsnIle: 1.41 ± 0.049	0.605AsnLys: 0.605 ± 0.027	2.299AsnLeu: 2.299 ± 0.048	0.577AsnMet: 0.577 ± 0.029	0.651AsnAsn: 0.651 ± 0.031	1.714AsnPro: 1.714 ± 0.049	0.681AsnGln: 0.681 ± 0.029	1.944AsnArg: 1.944 ± 0.048	1.264AsnSer: 1.264 ± 0.042	1.114AsnThr: 1.114 ± 0.041	1.866AsnVal: 1.866 ± 0.048	0.395AsnTrp: 0.395 ± 0.025	0.687AsnTyr: 0.687 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	6.919ProAla: 6.919 ± 0.125	0.292ProCys: 0.292 ± 0.019	3.956ProAsp: 3.956 ± 0.077	3.12ProGlu: 3.12 ± 0.059	1.712ProPhe: 1.712 ± 0.052	4.623ProGly: 4.623 ± 0.081	1.076ProHis: 1.076 ± 0.039	2.543ProIle: 2.543 ± 0.055	1.523ProLys: 1.523 ± 0.06	4.574ProLeu: 4.574 ± 0.079	1.193ProMet: 1.193 ± 0.042	1.254ProAsn: 1.254 ± 0.041	2.659ProPro: 2.659 ± 0.067	1.511ProGln: 1.511 ± 0.041	3.047ProArg: 3.047 ± 0.074	2.734ProSer: 2.734 ± 0.059	2.568ProThr: 2.568 ± 0.057	4.284ProVal: 4.284 ± 0.083	0.614ProTrp: 0.614 ± 0.027	1.095ProTyr: 1.095 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	3.958GlnAla: 3.958 ± 0.078	0.219GlnCys: 0.219 ± 0.017	1.345GlnAsp: 1.345 ± 0.038	1.084GlnGlu: 1.084 ± 0.044	1.066GlnPhe: 1.066 ± 0.038	2.32GlnGly: 2.32 ± 0.05	0.554GlnHis: 0.554 ± 0.023	1.593GlnIle: 1.593 ± 0.048	0.848GlnLys: 0.848 ± 0.037	3.02GlnLeu: 3.02 ± 0.064	0.745GlnMet: 0.745 ± 0.034	0.701GlnAsn: 0.701 ± 0.03	1.705GlnPro: 1.705 ± 0.052	1.032GlnGln: 1.032 ± 0.044	2.475GlnArg: 2.475 ± 0.068	1.763GlnSer: 1.763 ± 0.049	1.503GlnThr: 1.503 ± 0.049	1.959GlnVal: 1.959 ± 0.056	0.38GlnTrp: 0.38 ± 0.023	0.601GlnTyr: 0.601 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.642ArgAla: 8.642 ± 0.125	0.496ArgCys: 0.496 ± 0.026	4.887ArgAsp: 4.887 ± 0.08	3.875ArgGlu: 3.875 ± 0.08	2.839ArgPhe: 2.839 ± 0.068	5.03ArgGly: 5.03 ± 0.092	1.602ArgHis: 1.602 ± 0.047	4.338ArgIle: 4.338 ± 0.065	2.238ArgLys: 2.238 ± 0.059	7.837ArgLeu: 7.837 ± 0.119	1.879ArgMet: 1.879 ± 0.049	1.84ArgAsn: 1.84 ± 0.05	3.54ArgPro: 3.54 ± 0.075	2.141ArgGln: 2.141 ± 0.057	5.321ArgArg: 5.321 ± 0.106	3.819ArgSer: 3.819 ± 0.068	3.497ArgThr: 3.497 ± 0.068	4.758ArgVal: 4.758 ± 0.086	1.135ArgTrp: 1.135 ± 0.047	1.754ArgTyr: 1.754 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	6.638SerAla: 6.638 ± 0.104	0.446SerCys: 0.446 ± 0.03	3.739SerAsp: 3.739 ± 0.07	2.784SerGlu: 2.784 ± 0.066	2.099SerPhe: 2.099 ± 0.049	5.639SerGly: 5.639 ± 0.097	0.932SerHis: 0.932 ± 0.037	2.793SerIle: 2.793 ± 0.067	1.491SerLys: 1.491 ± 0.041	5.253SerLeu: 5.253 ± 0.086	1.131SerMet: 1.131 ± 0.041	1.484SerAsn: 1.484 ± 0.042	2.918SerPro: 2.918 ± 0.068	1.512SerGln: 1.512 ± 0.043	3.42SerArg: 3.42 ± 0.07	2.848SerSer: 2.848 ± 0.066	2.484SerThr: 2.484 ± 0.059	3.887SerVal: 3.887 ± 0.071	0.709SerTrp: 0.709 ± 0.032	1.308SerTyr: 1.308 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.363ThrAla: 6.363 ± 0.106	0.381ThrCys: 0.381 ± 0.021	3.077ThrAsp: 3.077 ± 0.065	2.268ThrGlu: 2.268 ± 0.056	1.622ThrPhe: 1.622 ± 0.048	5.333ThrGly: 5.333 ± 0.085	0.995ThrHis: 0.995 ± 0.036	3.344ThrIle: 3.344 ± 0.071	1.513ThrLys: 1.513 ± 0.054	5.73ThrLeu: 5.73 ± 0.087	1.271ThrMet: 1.271 ± 0.042	1.357ThrAsn: 1.357 ± 0.05	3.471ThrPro: 3.471 ± 0.07	1.544ThrGln: 1.544 ± 0.04	3.771ThrArg: 3.771 ± 0.069	2.721ThrSer: 2.721 ± 0.071	2.849ThrThr: 2.849 ± 0.067	4.02ThrVal: 4.02 ± 0.071	0.512ThrTrp: 0.512 ± 0.028	1.089ThrTyr: 1.089 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	10.436ValAla: 10.436 ± 0.147	0.508ValCys: 0.508 ± 0.027	4.521ValAsp: 4.521 ± 0.082	4.37ValGlu: 4.37 ± 0.086	2.289ValPhe: 2.289 ± 0.053	5.741ValGly: 5.741 ± 0.098	1.337ValHis: 1.337 ± 0.04	3.902ValIle: 3.902 ± 0.07	2.102ValLys: 2.102 ± 0.062	6.173ValLeu: 6.173 ± 0.1	1.643ValMet: 1.643 ± 0.05	1.752ValAsn: 1.752 ± 0.052	3.616ValPro: 3.616 ± 0.067	1.695ValGln: 1.695 ± 0.044	4.838ValArg: 4.838 ± 0.079	3.992ValSer: 3.992 ± 0.079	4.567ValThr: 4.567 ± 0.088	5.421ValVal: 5.421 ± 0.099	0.799ValTrp: 0.799 ± 0.036	1.434ValTyr: 1.434 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.334TrpAla: 1.334 ± 0.042	0.127TrpCys: 0.127 ± 0.012	0.778TrpAsp: 0.778 ± 0.037	0.499TrpGlu: 0.499 ± 0.027	0.504TrpPhe: 0.504 ± 0.024	0.909TrpGly: 0.909 ± 0.04	0.349TrpHis: 0.349 ± 0.024	0.669TrpIle: 0.669 ± 0.028	0.439TrpLys: 0.439 ± 0.027	1.7TrpLeu: 1.7 ± 0.05	0.349TrpMet: 0.349 ± 0.021	0.359TrpAsn: 0.359 ± 0.023	0.673TrpPro: 0.673 ± 0.035	0.596TrpGln: 0.596 ± 0.027	1.245TrpArg: 1.245 ± 0.042	0.85TrpSer: 0.85 ± 0.034	0.767TrpThr: 0.767 ± 0.03	0.791TrpVal: 0.791 ± 0.034	0.218TrpTrp: 0.218 ± 0.02	0.245TrpTyr: 0.245 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.803TyrAla: 2.803 ± 0.059	0.223TyrCys: 0.223 ± 0.016	1.711TyrAsp: 1.711 ± 0.059	1.099TyrGlu: 1.099 ± 0.041	0.872TyrPhe: 0.872 ± 0.041	2.149TyrGly: 2.149 ± 0.059	0.45TyrHis: 0.45 ± 0.027	0.875TyrIle: 0.875 ± 0.035	0.581TyrLys: 0.581 ± 0.03	2.086TyrLeu: 2.086 ± 0.048	0.355TyrMet: 0.355 ± 0.023	0.573TyrAsn: 0.573 ± 0.032	1.019TyrPro: 1.019 ± 0.036	0.65TyrGln: 0.65 ± 0.029	1.945TyrArg: 1.945 ± 0.055	1.148TyrSer: 1.148 ± 0.038	0.933TyrThr: 0.933 ± 0.035	1.555TyrVal: 1.555 ± 0.039	0.35TyrTrp: 0.35 ± 0.021	0.645TyrTyr: 0.645 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2468 proteins (779872 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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