Amino acid dipepetide frequency for Avon-Heathcote Estuary associated circular virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.878AlaAla: 6.878 ± 0.391
0.0AlaCys: 0.0 ± 0.0
8.253AlaAsp: 8.253 ± 1.718
5.502AlaGlu: 5.502 ± 1.145
1.376AlaPhe: 1.376 ± 1.327
4.127AlaGly: 4.127 ± 0.182
1.376AlaHis: 1.376 ± 1.327
2.751AlaIle: 2.751 ± 0.573
2.751AlaLys: 2.751 ± 2.654
1.376AlaLeu: 1.376 ± 1.327
1.376AlaMet: 1.376 ± 0.754
4.127AlaAsn: 4.127 ± 2.263
2.751AlaPro: 2.751 ± 1.509
5.502AlaGln: 5.502 ± 3.018
8.253AlaArg: 8.253 ± 1.718
5.502AlaSer: 5.502 ± 3.018
4.127AlaThr: 4.127 ± 2.263
6.878AlaVal: 6.878 ± 2.472
1.376AlaTrp: 1.376 ± 1.327
4.127AlaTyr: 4.127 ± 2.263
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.376CysCys: 1.376 ± 0.754
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.376CysGly: 1.376 ± 0.754
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.376CysLys: 1.376 ± 0.754
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.376CysArg: 1.376 ± 1.327
1.376CysSer: 1.376 ± 0.754
1.376CysThr: 1.376 ± 0.754
1.376CysVal: 1.376 ± 0.754
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
8.253AspAla: 8.253 ± 3.799
0.0AspCys: 0.0 ± 0.0
5.502AspAsp: 5.502 ± 0.936
2.751AspGlu: 2.751 ± 0.573
2.751AspPhe: 2.751 ± 0.573
4.127AspGly: 4.127 ± 1.9
1.376AspHis: 1.376 ± 1.327
2.751AspIle: 2.751 ± 2.654
0.0AspLys: 0.0 ± 0.0
5.502AspLeu: 5.502 ± 0.936
0.0AspMet: 0.0 ± 0.0
1.376AspAsn: 1.376 ± 0.754
4.127AspPro: 4.127 ± 1.9
0.0AspGln: 0.0 ± 0.0
2.751AspArg: 2.751 ± 0.573
2.751AspSer: 2.751 ± 2.654
1.376AspThr: 1.376 ± 0.754
4.127AspVal: 4.127 ± 0.182
1.376AspTrp: 1.376 ± 1.327
2.751AspTyr: 2.751 ± 0.573
0.0AspXaa: 0.0 ± 0.0
Glu
2.751GluAla: 2.751 ± 0.573
0.0GluCys: 0.0 ± 0.0
2.751GluAsp: 2.751 ± 0.573
0.0GluGlu: 0.0 ± 0.0
1.376GluPhe: 1.376 ± 1.327
1.376GluGly: 1.376 ± 0.754
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
2.751GluLys: 2.751 ± 1.509
5.502GluLeu: 5.502 ± 0.936
1.376GluMet: 1.376 ± 0.754
5.502GluAsn: 5.502 ± 0.936
4.127GluPro: 4.127 ± 0.182
0.0GluGln: 0.0 ± 0.0
2.751GluArg: 2.751 ± 2.654
1.376GluSer: 1.376 ± 1.327
2.751GluThr: 2.751 ± 0.573
5.502GluVal: 5.502 ± 1.145
1.376GluTrp: 1.376 ± 1.327
2.751GluTyr: 2.751 ± 0.573
0.0GluXaa: 0.0 ± 0.0
Phe
5.502PheAla: 5.502 ± 1.145
2.751PheCys: 2.751 ± 1.509
1.376PheAsp: 1.376 ± 1.327
1.376PheGlu: 1.376 ± 1.327
5.502PhePhe: 5.502 ± 3.018
6.878PheGly: 6.878 ± 1.691
0.0PheHis: 0.0 ± 0.0
1.376PheIle: 1.376 ± 0.754
1.376PheLys: 1.376 ± 1.327
4.127PheLeu: 4.127 ± 1.9
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.376PhePro: 1.376 ± 1.327
2.751PheGln: 2.751 ± 1.509
5.502PheArg: 5.502 ± 0.936
1.376PheSer: 1.376 ± 0.754
0.0PheThr: 0.0 ± 0.0
0.0PheVal: 0.0 ± 0.0
5.502PheTrp: 5.502 ± 1.145
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.127GlyAla: 4.127 ± 2.263
0.0GlyCys: 0.0 ± 0.0
2.751GlyAsp: 2.751 ± 2.654
0.0GlyGlu: 0.0 ± 0.0
4.127GlyPhe: 4.127 ± 0.182
11.004GlyGly: 11.004 ± 0.209
2.751GlyHis: 2.751 ± 0.573
9.629GlyIle: 9.629 ± 0.963
12.38GlyLys: 12.38 ± 2.627
8.253GlyLeu: 8.253 ± 2.445
2.751GlyMet: 2.751 ± 1.509
4.127GlyAsn: 4.127 ± 0.182
2.751GlyPro: 2.751 ± 1.509
2.751GlyGln: 2.751 ± 0.573
5.502GlyArg: 5.502 ± 0.936
2.751GlySer: 2.751 ± 2.654
4.127GlyThr: 4.127 ± 2.263
6.878GlyVal: 6.878 ± 2.472
0.0GlyTrp: 0.0 ± 0.0
1.376GlyTyr: 1.376 ± 1.327
0.0GlyXaa: 0.0 ± 0.0
His
4.127HisAla: 4.127 ± 1.9
0.0HisCys: 0.0 ± 0.0
1.376HisAsp: 1.376 ± 1.327
2.751HisGlu: 2.751 ± 0.573
1.376HisPhe: 1.376 ± 1.327
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.751HisIle: 2.751 ± 0.573
1.376HisLys: 1.376 ± 0.754
1.376HisLeu: 1.376 ± 1.327
1.376HisMet: 1.376 ± 1.327
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.376HisTrp: 1.376 ± 1.327
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.502IleAla: 5.502 ± 0.936
2.751IleCys: 2.751 ± 1.509
4.127IleAsp: 4.127 ± 1.9
5.502IleGlu: 5.502 ± 0.936
6.878IlePhe: 6.878 ± 1.691
5.502IleGly: 5.502 ± 3.018
1.376IleHis: 1.376 ± 0.754
0.0IleIle: 0.0 ± 0.0
1.376IleLys: 1.376 ± 0.754
4.127IleLeu: 4.127 ± 0.182
1.376IleMet: 1.376 ± 0.839
1.376IleAsn: 1.376 ± 0.754
4.127IlePro: 4.127 ± 1.9
0.0IleGln: 0.0 ± 0.0
2.751IleArg: 2.751 ± 0.573
2.751IleSer: 2.751 ± 1.509
2.751IleThr: 2.751 ± 2.654
1.376IleVal: 1.376 ± 0.754
1.376IleTrp: 1.376 ± 1.327
1.376IleTyr: 1.376 ± 1.327
0.0IleXaa: 0.0 ± 0.0
Lys
2.751LysAla: 2.751 ± 1.509
0.0LysCys: 0.0 ± 0.0
4.127LysAsp: 4.127 ± 0.182
2.751LysGlu: 2.751 ± 0.573
1.376LysPhe: 1.376 ± 1.327
5.502LysGly: 5.502 ± 1.145
1.376LysHis: 1.376 ± 1.327
4.127LysIle: 4.127 ± 1.9
2.751LysLys: 2.751 ± 1.509
0.0LysLeu: 0.0 ± 0.0
2.751LysMet: 2.751 ± 1.509
4.127LysAsn: 4.127 ± 2.263
0.0LysPro: 0.0 ± 0.0
4.127LysGln: 4.127 ± 2.263
4.127LysArg: 4.127 ± 1.9
8.253LysSer: 8.253 ± 2.445
6.878LysThr: 6.878 ± 3.772
2.751LysVal: 2.751 ± 0.573
0.0LysTrp: 0.0 ± 0.0
1.376LysTyr: 1.376 ± 0.754
0.0LysXaa: 0.0 ± 0.0
Leu
8.253LeuAla: 8.253 ± 2.445
1.376LeuCys: 1.376 ± 0.754
5.502LeuAsp: 5.502 ± 5.308
2.751LeuGlu: 2.751 ± 0.573
2.751LeuPhe: 2.751 ± 1.509
5.502LeuGly: 5.502 ± 3.227
1.376LeuHis: 1.376 ± 1.327
4.127LeuIle: 4.127 ± 2.263
4.127LeuLys: 4.127 ± 0.182
6.878LeuLeu: 6.878 ± 0.391
0.0LeuMet: 0.0 ± 0.0
4.127LeuAsn: 4.127 ± 2.263
5.502LeuPro: 5.502 ± 1.145
1.376LeuGln: 1.376 ± 0.754
6.878LeuArg: 6.878 ± 2.472
4.127LeuSer: 4.127 ± 0.182
2.751LeuThr: 2.751 ± 0.573
2.751LeuVal: 2.751 ± 0.573
0.0LeuTrp: 0.0 ± 0.0
5.502LeuTyr: 5.502 ± 0.936
0.0LeuXaa: 0.0 ± 0.0
Met
1.376MetAla: 1.376 ± 0.754
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.751MetGlu: 2.751 ± 1.509
0.0MetPhe: 0.0 ± 0.0
1.376MetGly: 1.376 ± 0.754
0.0MetHis: 0.0 ± 0.0
1.376MetIle: 1.376 ± 0.754
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
4.127MetAsn: 4.127 ± 0.182
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.376MetArg: 1.376 ± 0.754
2.751MetSer: 2.751 ± 1.509
0.0MetThr: 0.0 ± 0.0
1.376MetVal: 1.376 ± 1.327
0.0MetTrp: 0.0 ± 0.0
1.376MetTyr: 1.376 ± 0.754
0.0MetXaa: 0.0 ± 0.0
Asn
2.751AsnAla: 2.751 ± 1.509
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.376AsnGlu: 1.376 ± 1.327
2.751AsnPhe: 2.751 ± 0.573
1.376AsnGly: 1.376 ± 0.754
0.0AsnHis: 0.0 ± 0.0
4.127AsnIle: 4.127 ± 2.263
2.751AsnLys: 2.751 ± 1.509
1.376AsnLeu: 1.376 ± 1.327
0.0AsnMet: 0.0 ± 0.0
1.376AsnAsn: 1.376 ± 0.754
0.0AsnPro: 0.0 ± 0.0
5.502AsnGln: 5.502 ± 0.936
2.751AsnArg: 2.751 ± 1.509
0.0AsnSer: 0.0 ± 0.0
6.878AsnThr: 6.878 ± 1.691
6.878AsnVal: 6.878 ± 0.391
0.0AsnTrp: 0.0 ± 0.0
2.751AsnTyr: 2.751 ± 1.509
0.0AsnXaa: 0.0 ± 0.0
Pro
2.751ProAla: 2.751 ± 0.573
0.0ProCys: 0.0 ± 0.0
1.376ProAsp: 1.376 ± 0.754
1.376ProGlu: 1.376 ± 0.754
0.0ProPhe: 0.0 ± 0.0
4.127ProGly: 4.127 ± 2.263
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
1.376ProLys: 1.376 ± 1.327
4.127ProLeu: 4.127 ± 0.182
0.0ProMet: 0.0 ± 0.0
1.376ProAsn: 1.376 ± 1.327
1.376ProPro: 1.376 ± 1.327
4.127ProGln: 4.127 ± 2.263
5.502ProArg: 5.502 ± 1.145
1.376ProSer: 1.376 ± 0.754
5.502ProThr: 5.502 ± 1.145
4.127ProVal: 4.127 ± 1.9
1.376ProTrp: 1.376 ± 0.754
2.751ProTyr: 2.751 ± 0.573
0.0ProXaa: 0.0 ± 0.0
Gln
1.376GlnAla: 1.376 ± 1.327
0.0GlnCys: 0.0 ± 0.0
1.376GlnAsp: 1.376 ± 0.754
1.376GlnGlu: 1.376 ± 0.754
4.127GlnPhe: 4.127 ± 0.182
1.376GlnGly: 1.376 ± 0.754
0.0GlnHis: 0.0 ± 0.0
2.751GlnIle: 2.751 ± 1.509
2.751GlnLys: 2.751 ± 1.509
6.878GlnLeu: 6.878 ± 0.391
0.0GlnMet: 0.0 ± 0.0
1.376GlnAsn: 1.376 ± 0.754
1.376GlnPro: 1.376 ± 0.754
2.751GlnGln: 2.751 ± 1.509
1.376GlnArg: 1.376 ± 0.754
1.376GlnSer: 1.376 ± 0.754
4.127GlnThr: 4.127 ± 2.263
1.376GlnVal: 1.376 ± 0.754
1.376GlnTrp: 1.376 ± 0.754
1.376GlnTyr: 1.376 ± 0.754
0.0GlnXaa: 0.0 ± 0.0
Arg
2.751ArgAla: 2.751 ± 0.573
0.0ArgCys: 0.0 ± 0.0
1.376ArgAsp: 1.376 ± 0.754
8.253ArgGlu: 8.253 ± 3.799
2.751ArgPhe: 2.751 ± 2.654
9.629ArgGly: 9.629 ± 7.208
1.376ArgHis: 1.376 ± 1.327
8.253ArgIle: 8.253 ± 2.445
2.751ArgLys: 2.751 ± 0.573
6.878ArgLeu: 6.878 ± 4.554
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
2.751ArgPro: 2.751 ± 1.509
1.376ArgGln: 1.376 ± 0.754
8.253ArgArg: 8.253 ± 1.718
6.878ArgSer: 6.878 ± 1.691
6.878ArgThr: 6.878 ± 1.691
2.751ArgVal: 2.751 ± 1.509
1.376ArgTrp: 1.376 ± 1.327
1.376ArgTyr: 1.376 ± 1.327
0.0ArgXaa: 0.0 ± 0.0
Ser
5.502SerAla: 5.502 ± 3.227
0.0SerCys: 0.0 ± 0.0
4.127SerAsp: 4.127 ± 0.182
1.376SerGlu: 1.376 ± 0.754
5.502SerPhe: 5.502 ± 3.018
8.253SerGly: 8.253 ± 2.445
1.376SerHis: 1.376 ± 1.327
2.751SerIle: 2.751 ± 1.509
1.376SerLys: 1.376 ± 0.754
2.751SerLeu: 2.751 ± 1.509
2.751SerMet: 2.751 ± 1.509
1.376SerAsn: 1.376 ± 1.327
0.0SerPro: 0.0 ± 0.0
1.376SerGln: 1.376 ± 0.754
1.376SerArg: 1.376 ± 1.327
8.253SerSer: 8.253 ± 2.445
5.502SerThr: 5.502 ± 0.936
5.502SerVal: 5.502 ± 0.936
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.878ThrAla: 6.878 ± 3.772
0.0ThrCys: 0.0 ± 0.0
1.376ThrAsp: 1.376 ± 0.754
1.376ThrGlu: 1.376 ± 0.754
0.0ThrPhe: 0.0 ± 0.0
8.253ThrGly: 8.253 ± 2.445
4.127ThrHis: 4.127 ± 0.182
1.376ThrIle: 1.376 ± 1.327
6.878ThrLys: 6.878 ± 1.691
8.253ThrLeu: 8.253 ± 2.445
1.376ThrMet: 1.376 ± 1.245
1.376ThrAsn: 1.376 ± 0.754
5.502ThrPro: 5.502 ± 3.018
4.127ThrGln: 4.127 ± 0.182
6.878ThrArg: 6.878 ± 0.391
4.127ThrSer: 4.127 ± 0.182
6.878ThrThr: 6.878 ± 3.772
4.127ThrVal: 4.127 ± 0.182
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.127ValAla: 4.127 ± 0.182
0.0ValCys: 0.0 ± 0.0
4.127ValAsp: 4.127 ± 1.9
2.751ValGlu: 2.751 ± 0.573
1.376ValPhe: 1.376 ± 0.754
2.751ValGly: 2.751 ± 1.509
1.376ValHis: 1.376 ± 1.327
4.127ValIle: 4.127 ± 0.182
9.629ValLys: 9.629 ± 1.118
1.376ValLeu: 1.376 ± 1.327
1.376ValMet: 1.376 ± 0.754
4.127ValAsn: 4.127 ± 0.182
4.127ValPro: 4.127 ± 1.9
0.0ValGln: 0.0 ± 0.0
6.878ValArg: 6.878 ± 2.472
4.127ValSer: 4.127 ± 0.182
6.878ValThr: 6.878 ± 1.691
8.253ValVal: 8.253 ± 5.881
1.376ValTrp: 1.376 ± 1.327
1.376ValTyr: 1.376 ± 1.327
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.751TrpAsp: 2.751 ± 2.654
0.0TrpGlu: 0.0 ± 0.0
1.376TrpPhe: 1.376 ± 1.327
1.376TrpGly: 1.376 ± 1.327
0.0TrpHis: 0.0 ± 0.0
2.751TrpIle: 2.751 ± 2.654
1.376TrpLys: 1.376 ± 1.327
1.376TrpLeu: 1.376 ± 0.754
0.0TrpMet: 0.0 ± 0.0
2.751TrpAsn: 2.751 ± 0.573
0.0TrpPro: 0.0 ± 0.0
2.751TrpGln: 2.751 ± 0.573
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.376TrpThr: 1.376 ± 0.754
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.376TrpTyr: 1.376 ± 1.327
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.751TyrAla: 2.751 ± 0.573
1.376TyrCys: 1.376 ± 1.327
1.376TyrAsp: 1.376 ± 0.754
0.0TyrGlu: 0.0 ± 0.0
1.376TyrPhe: 1.376 ± 0.754
4.127TyrGly: 4.127 ± 0.182
0.0TyrHis: 0.0 ± 0.0
1.376TyrIle: 1.376 ± 0.754
0.0TyrLys: 0.0 ± 0.0
5.502TyrLeu: 5.502 ± 1.145
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.751TyrPro: 2.751 ± 0.573
0.0TyrGln: 0.0 ± 0.0
1.376TyrArg: 1.376 ± 1.327
0.0TyrSer: 0.0 ± 0.0
4.127TyrThr: 4.127 ± 2.263
4.127TyrVal: 4.127 ± 0.182
1.376TyrTrp: 1.376 ± 1.327
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (728 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski