Amino acid dipepetide frequency for Jatrophihabitans endophyticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.953AlaAla: 24.953 ± 0.256	1.023AlaCys: 1.023 ± 0.029	9.689AlaAsp: 9.689 ± 0.106	7.746AlaGlu: 7.746 ± 0.09	3.497AlaPhe: 3.497 ± 0.055	14.562AlaGly: 14.562 ± 0.124	2.651AlaHis: 2.651 ± 0.047	4.159AlaIle: 4.159 ± 0.062	2.596AlaLys: 2.596 ± 0.062	14.18AlaLeu: 14.18 ± 0.139	2.4AlaMet: 2.4 ± 0.043	2.19AlaAsn: 2.19 ± 0.04	6.965AlaPro: 6.965 ± 0.089	3.828AlaGln: 3.828 ± 0.058	11.013AlaArg: 11.013 ± 0.116	6.425AlaSer: 6.425 ± 0.089	8.778AlaThr: 8.778 ± 0.119	13.881AlaVal: 13.881 ± 0.124	1.741AlaTrp: 1.741 ± 0.041	2.443AlaTyr: 2.443 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.005CysAla: 1.005 ± 0.029	0.088CysCys: 0.088 ± 0.01	0.471CysAsp: 0.471 ± 0.02	0.338CysGlu: 0.338 ± 0.015	0.204CysPhe: 0.204 ± 0.013	0.845CysGly: 0.845 ± 0.026	0.166CysHis: 0.166 ± 0.01	0.159CysIle: 0.159 ± 0.012	0.099CysLys: 0.099 ± 0.01	0.634CysLeu: 0.634 ± 0.025	0.084CysMet: 0.084 ± 0.008	0.127CysAsn: 0.127 ± 0.01	0.48CysPro: 0.48 ± 0.02	0.153CysGln: 0.153 ± 0.009	0.591CysArg: 0.591 ± 0.021	0.413CysSer: 0.413 ± 0.018	0.481CysThr: 0.481 ± 0.02	0.682CysVal: 0.682 ± 0.023	0.111CysTrp: 0.111 ± 0.01	0.143CysTyr: 0.143 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.375AspAla: 9.375 ± 0.111	0.393AspCys: 0.393 ± 0.019	5.034AspAsp: 5.034 ± 0.084	4.212AspGlu: 4.212 ± 0.069	1.575AspPhe: 1.575 ± 0.032	6.803AspGly: 6.803 ± 0.079	1.374AspHis: 1.374 ± 0.031	1.765AspIle: 1.765 ± 0.039	0.949AspLys: 0.949 ± 0.029	6.381AspLeu: 6.381 ± 0.079	0.721AspMet: 0.721 ± 0.023	0.901AspAsn: 0.901 ± 0.029	4.56AspPro: 4.56 ± 0.063	1.409AspGln: 1.409 ± 0.031	5.057AspArg: 5.057 ± 0.069	2.406AspSer: 2.406 ± 0.051	3.468AspThr: 3.468 ± 0.068	6.74AspVal: 6.74 ± 0.071	0.884AspTrp: 0.884 ± 0.025	1.222AspTyr: 1.222 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.543GluAla: 5.543 ± 0.08	0.314GluCys: 0.314 ± 0.016	2.223GluAsp: 2.223 ± 0.041	1.882GluGlu: 1.882 ± 0.043	1.416GluPhe: 1.416 ± 0.035	3.063GluGly: 3.063 ± 0.053	1.558GluHis: 1.558 ± 0.033	2.066GluIle: 2.066 ± 0.041	0.902GluLys: 0.902 ± 0.03	6.599GluLeu: 6.599 ± 0.09	0.703GluMet: 0.703 ± 0.028	0.843GluAsn: 0.843 ± 0.025	2.976GluPro: 2.976 ± 0.057	2.144GluGln: 2.144 ± 0.042	5.128GluArg: 5.128 ± 0.075	2.233GluSer: 2.233 ± 0.043	2.622GluThr: 2.622 ± 0.047	4.147GluVal: 4.147 ± 0.061	0.659GluTrp: 0.659 ± 0.027	0.959GluTyr: 0.959 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.158PheAla: 4.158 ± 0.064	0.253PheCys: 0.253 ± 0.013	2.105PheAsp: 2.105 ± 0.04	1.258PheGlu: 1.258 ± 0.033	0.842PhePhe: 0.842 ± 0.028	3.232PheGly: 3.232 ± 0.053	0.527PheHis: 0.527 ± 0.02	0.531PheIle: 0.531 ± 0.021	0.391PheLys: 0.391 ± 0.018	2.367PheLeu: 2.367 ± 0.046	0.281PheMet: 0.281 ± 0.015	0.489PheAsn: 0.489 ± 0.021	1.294PhePro: 1.294 ± 0.028	0.548PheGln: 0.548 ± 0.021	1.698PheArg: 1.698 ± 0.038	1.299PheSer: 1.299 ± 0.036	1.871PheThr: 1.871 ± 0.043	2.868PheVal: 2.868 ± 0.05	0.382PheTrp: 0.382 ± 0.016	0.534PheTyr: 0.534 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	11.484GlyAla: 11.484 ± 0.1	0.827GlyCys: 0.827 ± 0.026	5.74GlyAsp: 5.74 ± 0.099	4.619GlyGlu: 4.619 ± 0.065	2.794GlyPhe: 2.794 ± 0.05	8.945GlyGly: 8.945 ± 0.137	2.167GlyHis: 2.167 ± 0.045	3.383GlyIle: 3.383 ± 0.054	2.07GlyLys: 2.07 ± 0.044	8.921GlyLeu: 8.921 ± 0.1	1.872GlyMet: 1.872 ± 0.036	1.801GlyAsn: 1.801 ± 0.041	4.489GlyPro: 4.489 ± 0.057	2.479GlyGln: 2.479 ± 0.055	7.926GlyArg: 7.926 ± 0.079	5.79GlySer: 5.79 ± 0.113	6.486GlyThr: 6.486 ± 0.105	8.553GlyVal: 8.553 ± 0.079	1.684GlyTrp: 1.684 ± 0.039	2.351GlyTyr: 2.351 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.747HisAla: 2.747 ± 0.049	0.19HisCys: 0.19 ± 0.011	1.654HisAsp: 1.654 ± 0.038	1.173HisGlu: 1.173 ± 0.032	0.576HisPhe: 0.576 ± 0.024	2.356HisGly: 2.356 ± 0.048	0.639HisHis: 0.639 ± 0.024	0.508HisIle: 0.508 ± 0.02	0.279HisLys: 0.279 ± 0.015	2.086HisLeu: 2.086 ± 0.035	0.26HisMet: 0.26 ± 0.014	0.346HisAsn: 0.346 ± 0.017	1.537HisPro: 1.537 ± 0.038	0.493HisGln: 0.493 ± 0.017	1.992HisArg: 1.992 ± 0.039	0.873HisSer: 0.873 ± 0.026	1.045HisThr: 1.045 ± 0.033	2.066HisVal: 2.066 ± 0.041	0.307HisTrp: 0.307 ± 0.014	0.519HisTyr: 0.519 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.049IleAla: 5.049 ± 0.068	0.275IleCys: 0.275 ± 0.016	2.378IleAsp: 2.378 ± 0.044	1.93IleGlu: 1.93 ± 0.042	0.723IlePhe: 0.723 ± 0.029	3.546IleGly: 3.546 ± 0.059	0.51IleHis: 0.51 ± 0.02	0.789IleIle: 0.789 ± 0.03	0.594IleLys: 0.594 ± 0.022	2.093IleLeu: 2.093 ± 0.045	0.399IleMet: 0.399 ± 0.017	0.632IleAsn: 0.632 ± 0.023	1.429IlePro: 1.429 ± 0.041	0.613IleGln: 0.613 ± 0.023	2.03IleArg: 2.03 ± 0.04	1.565IleSer: 1.565 ± 0.035	2.086IleThr: 2.086 ± 0.04	3.289IleVal: 3.289 ± 0.061	0.311IleTrp: 0.311 ± 0.015	0.517IleTyr: 0.517 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.223LysAla: 2.223 ± 0.057	0.078LysCys: 0.078 ± 0.008	0.971LysAsp: 0.971 ± 0.032	0.65LysGlu: 0.65 ± 0.025	0.415LysPhe: 0.415 ± 0.018	1.38LysGly: 1.38 ± 0.038	0.398LysHis: 0.398 ± 0.019	0.747LysIle: 0.747 ± 0.023	0.608LysLys: 0.608 ± 0.036	1.605LysLeu: 1.605 ± 0.04	0.264LysMet: 0.264 ± 0.014	0.405LysAsn: 0.405 ± 0.02	1.011LysPro: 1.011 ± 0.031	0.638LysGln: 0.638 ± 0.023	1.308LysArg: 1.308 ± 0.035	0.993LysSer: 0.993 ± 0.028	1.173LysThr: 1.173 ± 0.039	1.502LysVal: 1.502 ± 0.042	0.186LysTrp: 0.186 ± 0.012	0.416LysTyr: 0.416 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	16.572LeuAla: 16.572 ± 0.144	0.659LeuCys: 0.659 ± 0.024	7.178LeuAsp: 7.178 ± 0.087	3.823LeuGlu: 3.823 ± 0.057	2.494LeuPhe: 2.494 ± 0.053	9.336LeuGly: 9.336 ± 0.105	2.128LeuHis: 2.128 ± 0.039	2.553LeuIle: 2.553 ± 0.057	1.269LeuLys: 1.269 ± 0.037	10.593LeuLeu: 10.593 ± 0.121	1.14LeuMet: 1.14 ± 0.029	1.447LeuAsn: 1.447 ± 0.036	5.947LeuPro: 5.947 ± 0.07	2.342LeuGln: 2.342 ± 0.041	8.827LeuArg: 8.827 ± 0.111	4.717LeuSer: 4.717 ± 0.062	6.287LeuThr: 6.287 ± 0.069	10.433LeuVal: 10.433 ± 0.11	1.023LeuTrp: 1.023 ± 0.027	1.545LeuTyr: 1.545 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	1.911MetAla: 1.911 ± 0.041	0.108MetCys: 0.108 ± 0.009	0.64MetAsp: 0.64 ± 0.02	0.44MetGlu: 0.44 ± 0.019	0.427MetPhe: 0.427 ± 0.018	1.049MetGly: 1.049 ± 0.03	0.332MetHis: 0.332 ± 0.017	0.633MetIle: 0.633 ± 0.024	0.298MetLys: 0.298 ± 0.015	1.504MetLeu: 1.504 ± 0.038	0.241MetMet: 0.241 ± 0.014	0.326MetAsn: 0.326 ± 0.014	0.983MetPro: 0.983 ± 0.028	0.454MetGln: 0.454 ± 0.02	1.293MetArg: 1.293 ± 0.03	1.223MetSer: 1.223 ± 0.028	1.793MetThr: 1.793 ± 0.035	1.093MetVal: 1.093 ± 0.029	0.168MetTrp: 0.168 ± 0.011	0.25MetTyr: 0.25 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.221AsnAla: 2.221 ± 0.049	0.153AsnCys: 0.153 ± 0.01	1.02AsnAsp: 1.02 ± 0.03	0.724AsnGlu: 0.724 ± 0.023	0.484AsnPhe: 0.484 ± 0.021	1.796AsnGly: 1.796 ± 0.044	0.36AsnHis: 0.36 ± 0.019	0.587AsnIle: 0.587 ± 0.021	0.336AsnLys: 0.336 ± 0.018	1.67AsnLeu: 1.67 ± 0.032	0.241AsnMet: 0.241 ± 0.013	0.42AsnAsn: 0.42 ± 0.022	1.263AsnPro: 1.263 ± 0.028	0.485AsnGln: 0.485 ± 0.02	1.272AsnArg: 1.272 ± 0.031	0.878AsnSer: 0.878 ± 0.031	1.038AsnThr: 1.038 ± 0.033	1.567AsnVal: 1.567 ± 0.035	0.238AsnTrp: 0.238 ± 0.015	0.421AsnTyr: 0.421 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	8.882ProAla: 8.882 ± 0.112	0.289ProCys: 0.289 ± 0.016	4.392ProAsp: 4.392 ± 0.065	2.956ProGlu: 2.956 ± 0.048	1.485ProPhe: 1.485 ± 0.035	5.843ProGly: 5.843 ± 0.069	1.186ProHis: 1.186 ± 0.032	1.554ProIle: 1.554 ± 0.029	0.914ProLys: 0.914 ± 0.029	4.729ProLeu: 4.729 ± 0.064	0.883ProMet: 0.883 ± 0.029	0.938ProAsn: 0.938 ± 0.026	3.298ProPro: 3.298 ± 0.072	1.498ProGln: 1.498 ± 0.035	4.077ProArg: 4.077 ± 0.068	3.05ProSer: 3.05 ± 0.062	3.848ProThr: 3.848 ± 0.068	5.281ProVal: 5.281 ± 0.07	0.807ProTrp: 0.807 ± 0.024	1.088ProTyr: 1.088 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.305GlnAla: 3.305 ± 0.057	0.162GlnCys: 0.162 ± 0.011	1.241GlnAsp: 1.241 ± 0.031	0.952GlnGlu: 0.952 ± 0.03	0.735GlnPhe: 0.735 ± 0.025	1.982GlnGly: 1.982 ± 0.046	0.657GlnHis: 0.657 ± 0.023	0.943GlnIle: 0.943 ± 0.022	0.447GlnLys: 0.447 ± 0.018	3.428GlnLeu: 3.428 ± 0.061	0.369GlnMet: 0.369 ± 0.015	0.527GlnAsn: 0.527 ± 0.02	1.608GlnPro: 1.608 ± 0.04	1.307GlnGln: 1.307 ± 0.042	2.64GlnArg: 2.64 ± 0.045	1.212GlnSer: 1.212 ± 0.035	1.35GlnThr: 1.35 ± 0.033	2.473GlnVal: 2.473 ± 0.042	0.403GlnTrp: 0.403 ± 0.018	0.604GlnTyr: 0.604 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	10.504ArgAla: 10.504 ± 0.126	0.606ArgCys: 0.606 ± 0.02	5.109ArgAsp: 5.109 ± 0.069	4.181ArgGlu: 4.181 ± 0.06	2.395ArgPhe: 2.395 ± 0.04	6.073ArgGly: 6.073 ± 0.067	2.064ArgHis: 2.064 ± 0.042	2.975ArgIle: 2.975 ± 0.049	1.199ArgLys: 1.199 ± 0.034	8.513ArgLeu: 8.513 ± 0.096	1.616ArgMet: 1.616 ± 0.038	1.38ArgAsn: 1.38 ± 0.028	5.029ArgPro: 5.029 ± 0.067	2.118ArgGln: 2.118 ± 0.047	8.535ArgArg: 8.535 ± 0.104	4.414ArgSer: 4.414 ± 0.061	5.278ArgThr: 5.278 ± 0.073	6.919ArgVal: 6.919 ± 0.075	1.466ArgTrp: 1.466 ± 0.034	1.831ArgTyr: 1.831 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	6.993SerAla: 6.993 ± 0.094	0.388SerCys: 0.388 ± 0.02	2.823SerAsp: 2.823 ± 0.05	1.967SerGlu: 1.967 ± 0.037	1.568SerPhe: 1.568 ± 0.039	5.789SerGly: 5.789 ± 0.169	0.922SerHis: 0.922 ± 0.025	1.668SerIle: 1.668 ± 0.04	0.86SerLys: 0.86 ± 0.028	4.838SerLeu: 4.838 ± 0.069	1.04SerMet: 1.04 ± 0.024	0.894SerAsn: 0.894 ± 0.025	2.977SerPro: 2.977 ± 0.047	1.205SerGln: 1.205 ± 0.031	3.81SerArg: 3.81 ± 0.061	3.432SerSer: 3.432 ± 0.092	3.438SerThr: 3.438 ± 0.076	4.513SerVal: 4.513 ± 0.057	0.844SerTrp: 0.844 ± 0.024	1.198SerTyr: 1.198 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	9.439ThrAla: 9.439 ± 0.108	0.406ThrCys: 0.406 ± 0.017	3.877ThrAsp: 3.877 ± 0.063	2.668ThrGlu: 2.668 ± 0.046	1.82ThrPhe: 1.82 ± 0.041	6.668ThrGly: 6.668 ± 0.114	1.216ThrHis: 1.216 ± 0.031	2.139ThrIle: 2.139 ± 0.044	1.143ThrLys: 1.143 ± 0.036	6.084ThrLeu: 6.084 ± 0.071	0.998ThrMet: 0.998 ± 0.028	1.134ThrAsn: 1.134 ± 0.032	3.941ThrPro: 3.941 ± 0.065	1.386ThrGln: 1.386 ± 0.033	4.317ThrArg: 4.317 ± 0.059	3.756ThrSer: 3.756 ± 0.084	4.713ThrThr: 4.713 ± 0.098	6.813ThrVal: 6.813 ± 0.099	0.893ThrTrp: 0.893 ± 0.026	1.322ThrTyr: 1.322 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	14.291ValAla: 14.291 ± 0.117	0.761ValCys: 0.761 ± 0.025	6.432ValAsp: 6.432 ± 0.075	4.981ValGlu: 4.981 ± 0.069	2.391ValPhe: 2.391 ± 0.042	8.122ValGly: 8.122 ± 0.089	2.03ValHis: 2.03 ± 0.038	2.715ValIle: 2.715 ± 0.05	1.468ValLys: 1.468 ± 0.043	10.264ValLeu: 10.264 ± 0.115	1.27ValMet: 1.27 ± 0.037	1.686ValAsn: 1.686 ± 0.039	5.439ValPro: 5.439 ± 0.071	2.146ValGln: 2.146 ± 0.045	7.529ValArg: 7.529 ± 0.089	4.616ValSer: 4.616 ± 0.063	6.837ValThr: 6.837 ± 0.1	10.892ValVal: 10.892 ± 0.124	1.072ValTrp: 1.072 ± 0.028	1.574ValTyr: 1.574 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.475TrpAla: 1.475 ± 0.029	0.14TrpCys: 0.14 ± 0.012	0.787TrpAsp: 0.787 ± 0.025	0.51TrpGlu: 0.51 ± 0.019	0.474TrpPhe: 0.474 ± 0.019	0.946TrpGly: 0.946 ± 0.027	0.372TrpHis: 0.372 ± 0.018	0.49TrpIle: 0.49 ± 0.019	0.216TrpLys: 0.216 ± 0.013	1.705TrpLeu: 1.705 ± 0.045	0.191TrpMet: 0.191 ± 0.013	0.339TrpAsn: 0.339 ± 0.018	0.719TrpPro: 0.719 ± 0.024	0.56TrpGln: 0.56 ± 0.022	1.323TrpArg: 1.323 ± 0.033	0.911TrpSer: 0.911 ± 0.027	0.998TrpThr: 0.998 ± 0.028	1.017TrpVal: 1.017 ± 0.026	0.307TrpTrp: 0.307 ± 0.016	0.306TrpTyr: 0.306 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.591TyrAla: 2.591 ± 0.05	0.162TyrCys: 0.162 ± 0.013	1.464TyrAsp: 1.464 ± 0.044	0.972TyrGlu: 0.972 ± 0.029	0.613TyrPhe: 0.613 ± 0.023	2.043TyrGly: 2.043 ± 0.046	0.388TyrHis: 0.388 ± 0.018	0.395TyrIle: 0.395 ± 0.017	0.334TyrLys: 0.334 ± 0.016	2.119TyrLeu: 2.119 ± 0.042	0.192TyrMet: 0.192 ± 0.011	0.35TyrAsn: 0.35 ± 0.018	1.053TyrPro: 1.053 ± 0.029	0.536TyrGln: 0.536 ± 0.021	1.837TyrArg: 1.837 ± 0.036	0.962TyrSer: 0.962 ± 0.031	1.143TyrThr: 1.143 ± 0.03	1.787TyrVal: 1.787 ± 0.04	0.302TyrTrp: 0.302 ± 0.015	0.466TyrTyr: 0.466 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4181 proteins (1383085 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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