Amino acid dipepetide frequency for Culex tritaeniorhynchus rhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.225AlaAla: 6.225 ± 1.216
1.698AlaCys: 1.698 ± 0.862
5.376AlaAsp: 5.376 ± 0.873
5.942AlaGlu: 5.942 ± 0.876
3.679AlaPhe: 3.679 ± 1.185
4.527AlaGly: 4.527 ± 0.916
1.415AlaHis: 1.415 ± 0.521
4.527AlaIle: 4.527 ± 0.998
3.396AlaLys: 3.396 ± 1.387
7.074AlaLeu: 7.074 ± 0.939
1.698AlaMet: 1.698 ± 0.878
1.981AlaAsn: 1.981 ± 0.502
3.396AlaPro: 3.396 ± 2.717
1.981AlaGln: 1.981 ± 0.538
3.679AlaArg: 3.679 ± 1.103
6.225AlaSer: 6.225 ± 1.068
4.527AlaThr: 4.527 ± 0.832
4.244AlaVal: 4.244 ± 1.389
0.566AlaTrp: 0.566 ± 0.297
2.83AlaTyr: 2.83 ± 1.391
0.0AlaXaa: 0.0 ± 0.0
Cys
0.849CysAla: 0.849 ± 0.401
0.283CysCys: 0.283 ± 0.149
0.849CysAsp: 0.849 ± 0.446
0.283CysGlu: 0.283 ± 0.149
0.849CysPhe: 0.849 ± 0.401
1.132CysGly: 1.132 ± 0.567
0.283CysHis: 0.283 ± 0.149
0.566CysIle: 0.566 ± 0.274
0.283CysLys: 0.283 ± 0.149
2.83CysLeu: 2.83 ± 0.666
0.0CysMet: 0.0 ± 0.0
0.566CysAsn: 0.566 ± 0.325
0.849CysPro: 0.849 ± 0.401
0.0CysGln: 0.0 ± 0.0
1.698CysArg: 1.698 ± 0.693
2.83CysSer: 2.83 ± 1.824
1.132CysThr: 1.132 ± 0.375
1.132CysVal: 1.132 ± 0.294
0.566CysTrp: 0.566 ± 0.297
0.566CysTyr: 0.566 ± 0.325
0.0CysXaa: 0.0 ± 0.0
Asp
5.093AspAla: 5.093 ± 1.307
1.132AspCys: 1.132 ± 0.745
2.83AspAsp: 2.83 ± 1.487
3.113AspGlu: 3.113 ± 0.599
1.698AspPhe: 1.698 ± 0.594
4.244AspGly: 4.244 ± 0.541
2.547AspHis: 2.547 ± 0.726
3.396AspIle: 3.396 ± 0.886
2.83AspLys: 2.83 ± 1.07
5.659AspLeu: 5.659 ± 1.292
1.415AspMet: 1.415 ± 0.644
1.981AspAsn: 1.981 ± 0.725
4.527AspPro: 4.527 ± 1.003
1.132AspGln: 1.132 ± 0.4
3.679AspArg: 3.679 ± 1.317
1.415AspSer: 1.415 ± 0.237
2.264AspThr: 2.264 ± 0.62
3.396AspVal: 3.396 ± 0.864
0.849AspTrp: 0.849 ± 0.318
1.981AspTyr: 1.981 ± 0.725
0.0AspXaa: 0.0 ± 0.0
Glu
2.547GluAla: 2.547 ± 0.812
1.132GluCys: 1.132 ± 0.734
2.83GluAsp: 2.83 ± 0.581
3.962GluGlu: 3.962 ± 0.779
3.396GluPhe: 3.396 ± 0.775
5.376GluGly: 5.376 ± 1.374
1.132GluHis: 1.132 ± 0.734
5.093GluIle: 5.093 ± 1.228
2.547GluLys: 2.547 ± 0.601
4.244GluLeu: 4.244 ± 0.524
1.415GluMet: 1.415 ± 0.756
2.264GluAsn: 2.264 ± 0.667
3.396GluPro: 3.396 ± 1.111
0.566GluGln: 0.566 ± 0.368
2.83GluArg: 2.83 ± 0.507
4.244GluSer: 4.244 ± 1.862
4.527GluThr: 4.527 ± 1.355
5.942GluVal: 5.942 ± 1.754
0.849GluTrp: 0.849 ± 0.267
1.132GluTyr: 1.132 ± 0.65
0.0GluXaa: 0.0 ± 0.0
Phe
2.264PheAla: 2.264 ± 0.751
0.283PheCys: 0.283 ± 0.149
3.113PheAsp: 3.113 ± 0.412
1.132PheGlu: 1.132 ± 0.4
1.415PhePhe: 1.415 ± 0.443
3.113PheGly: 3.113 ± 0.871
0.566PheHis: 0.566 ± 0.297
2.83PheIle: 2.83 ± 0.617
2.547PheLys: 2.547 ± 0.601
4.527PheLeu: 4.527 ± 1.638
0.566PheMet: 0.566 ± 0.325
2.547PheAsn: 2.547 ± 0.585
2.547PhePro: 2.547 ± 0.771
2.547PheGln: 2.547 ± 1.001
2.264PheArg: 2.264 ± 0.646
1.415PheSer: 1.415 ± 0.443
1.698PheThr: 1.698 ± 0.732
1.981PheVal: 1.981 ± 0.725
0.849PheTrp: 0.849 ± 0.612
0.566PheTyr: 0.566 ± 0.297
0.0PheXaa: 0.0 ± 0.0
Gly
5.942GlyAla: 5.942 ± 2.308
1.415GlyCys: 1.415 ± 0.413
5.376GlyAsp: 5.376 ± 1.319
3.679GlyGlu: 3.679 ± 0.582
1.981GlyPhe: 1.981 ± 0.502
4.527GlyGly: 4.527 ± 0.9
2.264GlyHis: 2.264 ± 0.669
3.679GlyIle: 3.679 ± 1.034
1.981GlyLys: 1.981 ± 0.537
9.338GlyLeu: 9.338 ± 1.838
0.566GlyMet: 0.566 ± 0.368
3.396GlyAsn: 3.396 ± 0.631
3.962GlyPro: 3.962 ± 1.592
2.264GlyGln: 2.264 ± 0.731
6.225GlyArg: 6.225 ± 0.799
6.225GlySer: 6.225 ± 1.647
3.396GlyThr: 3.396 ± 0.653
5.376GlyVal: 5.376 ± 1.341
1.698GlyTrp: 1.698 ± 0.594
3.396GlyTyr: 3.396 ± 0.932
0.0GlyXaa: 0.0 ± 0.0
His
1.132HisAla: 1.132 ± 0.294
0.0HisCys: 0.0 ± 0.0
1.132HisAsp: 1.132 ± 0.595
0.849HisGlu: 0.849 ± 0.318
0.566HisPhe: 0.566 ± 0.325
1.415HisGly: 1.415 ± 0.237
0.566HisHis: 0.566 ± 0.274
1.415HisIle: 1.415 ± 0.743
1.132HisLys: 1.132 ± 0.48
4.81HisLeu: 4.81 ± 0.86
0.566HisMet: 0.566 ± 0.274
0.566HisAsn: 0.566 ± 0.297
2.83HisPro: 2.83 ± 0.508
0.849HisGln: 0.849 ± 0.446
1.132HisArg: 1.132 ± 0.4
1.132HisSer: 1.132 ± 0.375
0.849HisThr: 0.849 ± 0.318
1.698HisVal: 1.698 ± 0.822
0.566HisTrp: 0.566 ± 0.274
0.849HisTyr: 0.849 ± 0.318
0.0HisXaa: 0.0 ± 0.0
Ile
4.81IleAla: 4.81 ± 0.636
0.566IleCys: 0.566 ± 0.325
1.981IleAsp: 1.981 ± 0.582
4.527IleGlu: 4.527 ± 1.197
2.264IlePhe: 2.264 ± 0.846
5.093IleGly: 5.093 ± 1.467
1.132IleHis: 1.132 ± 0.595
2.83IleIle: 2.83 ± 0.615
3.396IleLys: 3.396 ± 0.348
3.679IleLeu: 3.679 ± 0.651
1.132IleMet: 1.132 ± 0.375
1.698IleAsn: 1.698 ± 0.594
4.244IlePro: 4.244 ± 1.071
1.415IleGln: 1.415 ± 0.411
5.093IleArg: 5.093 ± 1.123
6.791IleSer: 6.791 ± 1.615
3.396IleThr: 3.396 ± 0.737
2.83IleVal: 2.83 ± 0.519
1.415IleTrp: 1.415 ± 0.474
1.415IleTyr: 1.415 ± 0.237
0.0IleXaa: 0.0 ± 0.0
Lys
3.962LysAla: 3.962 ± 1.147
1.698LysCys: 1.698 ± 0.449
1.415LysAsp: 1.415 ± 0.443
4.244LysGlu: 4.244 ± 0.802
1.415LysPhe: 1.415 ± 0.726
3.962LysGly: 3.962 ± 1.04
0.566LysHis: 0.566 ± 0.297
2.264LysIle: 2.264 ± 0.41
3.113LysLys: 3.113 ± 0.628
4.244LysLeu: 4.244 ± 0.54
0.566LysMet: 0.566 ± 0.325
0.283LysAsn: 0.283 ± 0.149
2.264LysPro: 2.264 ± 0.62
0.283LysGln: 0.283 ± 0.393
3.113LysArg: 3.113 ± 0.988
3.396LysSer: 3.396 ± 1.147
5.093LysThr: 5.093 ± 2.277
2.547LysVal: 2.547 ± 0.842
1.415LysTrp: 1.415 ± 0.743
0.849LysTyr: 0.849 ± 0.267
0.0LysXaa: 0.0 ± 0.0
Leu
10.187LeuAla: 10.187 ± 1.887
1.698LeuCys: 1.698 ± 0.571
7.923LeuAsp: 7.923 ± 1.969
5.376LeuGlu: 5.376 ± 0.372
4.527LeuPhe: 4.527 ± 0.578
9.055LeuGly: 9.055 ± 1.554
3.113LeuHis: 3.113 ± 0.79
6.225LeuIle: 6.225 ± 2.022
4.81LeuLys: 4.81 ± 0.635
9.621LeuLeu: 9.621 ± 1.62
3.679LeuMet: 3.679 ± 1.113
2.547LeuAsn: 2.547 ± 0.426
5.376LeuPro: 5.376 ± 1.292
2.547LeuGln: 2.547 ± 0.537
5.659LeuArg: 5.659 ± 1.892
6.225LeuSer: 6.225 ± 1.621
4.527LeuThr: 4.527 ± 0.656
2.264LeuVal: 2.264 ± 0.846
1.132LeuTrp: 1.132 ± 0.375
2.547LeuTyr: 2.547 ± 0.567
0.0LeuXaa: 0.0 ± 0.0
Met
2.264MetAla: 2.264 ± 0.588
0.849MetCys: 0.849 ± 0.446
1.132MetAsp: 1.132 ± 0.567
0.849MetGlu: 0.849 ± 0.453
1.132MetPhe: 1.132 ± 0.4
0.849MetGly: 0.849 ± 0.318
0.566MetHis: 0.566 ± 0.274
1.132MetIle: 1.132 ± 0.732
0.566MetLys: 0.566 ± 0.325
2.83MetLeu: 2.83 ± 0.473
0.283MetMet: 0.283 ± 0.149
0.849MetAsn: 0.849 ± 0.446
0.283MetPro: 0.283 ± 0.393
0.283MetGln: 0.283 ± 0.149
2.264MetArg: 2.264 ± 0.92
1.981MetSer: 1.981 ± 1.152
1.132MetThr: 1.132 ± 0.4
0.849MetVal: 0.849 ± 0.267
0.849MetTrp: 0.849 ± 0.318
1.132MetTyr: 1.132 ± 0.334
0.0MetXaa: 0.0 ± 0.0
Asn
1.981AsnAla: 1.981 ± 0.945
0.283AsnCys: 0.283 ± 0.564
0.849AsnAsp: 0.849 ± 0.446
2.264AsnGlu: 2.264 ± 0.491
1.698AsnPhe: 1.698 ± 0.709
1.698AsnGly: 1.698 ± 0.654
1.132AsnHis: 1.132 ± 0.375
1.981AsnIle: 1.981 ± 0.725
1.132AsnLys: 1.132 ± 0.412
4.527AsnLeu: 4.527 ± 1.283
0.283AsnMet: 0.283 ± 0.149
1.698AsnAsn: 1.698 ± 0.5
2.264AsnPro: 2.264 ± 1.19
1.132AsnGln: 1.132 ± 0.48
1.415AsnArg: 1.415 ± 0.237
2.547AsnSer: 2.547 ± 0.432
2.547AsnThr: 2.547 ± 1.059
1.132AsnVal: 1.132 ± 0.294
1.415AsnTrp: 1.415 ± 0.743
1.415AsnTyr: 1.415 ± 0.743
0.0AsnXaa: 0.0 ± 0.0
Pro
5.376ProAla: 5.376 ± 1.564
1.132ProCys: 1.132 ± 0.294
1.698ProAsp: 1.698 ± 0.264
5.093ProGlu: 5.093 ± 1.049
1.415ProPhe: 1.415 ± 0.443
4.244ProGly: 4.244 ± 2.351
1.132ProHis: 1.132 ± 0.334
4.244ProIle: 4.244 ± 0.783
1.698ProLys: 1.698 ± 0.902
4.527ProLeu: 4.527 ± 1.298
0.849ProMet: 0.849 ± 0.401
1.981ProAsn: 1.981 ± 0.706
2.547ProPro: 2.547 ± 1.086
0.849ProGln: 0.849 ± 0.453
3.396ProArg: 3.396 ± 0.691
5.376ProSer: 5.376 ± 0.851
3.113ProThr: 3.113 ± 1.096
3.396ProVal: 3.396 ± 1.176
1.132ProTrp: 1.132 ± 0.294
1.698ProTyr: 1.698 ± 0.636
0.0ProXaa: 0.0 ± 0.0
Gln
2.264GlnAla: 2.264 ± 0.649
0.566GlnCys: 0.566 ± 0.297
1.132GlnAsp: 1.132 ± 0.334
1.415GlnGlu: 1.415 ± 0.626
1.132GlnPhe: 1.132 ± 0.595
1.415GlnGly: 1.415 ± 0.413
1.132GlnHis: 1.132 ± 0.65
1.415GlnIle: 1.415 ± 0.642
1.132GlnLys: 1.132 ± 0.595
2.264GlnLeu: 2.264 ± 0.646
1.132GlnMet: 1.132 ± 0.375
0.566GlnAsn: 0.566 ± 0.297
1.415GlnPro: 1.415 ± 0.411
1.132GlnGln: 1.132 ± 0.375
2.547GlnArg: 2.547 ± 0.781
1.415GlnSer: 1.415 ± 1.11
1.698GlnThr: 1.698 ± 0.636
1.698GlnVal: 1.698 ± 0.513
0.283GlnTrp: 0.283 ± 0.351
1.698GlnTyr: 1.698 ± 0.629
0.0GlnXaa: 0.0 ± 0.0
Arg
7.074ArgAla: 7.074 ± 1.885
0.566ArgCys: 0.566 ± 0.274
4.527ArgAsp: 4.527 ± 1.013
3.679ArgGlu: 3.679 ± 0.828
3.113ArgPhe: 3.113 ± 0.707
5.659ArgGly: 5.659 ± 1.031
1.132ArgHis: 1.132 ± 0.65
4.244ArgIle: 4.244 ± 0.657
1.415ArgLys: 1.415 ± 0.411
5.942ArgLeu: 5.942 ± 0.935
1.415ArgMet: 1.415 ± 0.58
1.698ArgAsn: 1.698 ± 0.449
3.962ArgPro: 3.962 ± 1.39
2.547ArgGln: 2.547 ± 1.001
2.83ArgArg: 2.83 ± 0.831
4.527ArgSer: 4.527 ± 0.372
3.962ArgThr: 3.962 ± 0.688
3.396ArgVal: 3.396 ± 0.83
1.132ArgTrp: 1.132 ± 0.548
1.981ArgTyr: 1.981 ± 1.317
0.0ArgXaa: 0.0 ± 0.0
Ser
4.527SerAla: 4.527 ± 0.476
0.849SerCys: 0.849 ± 0.267
4.527SerAsp: 4.527 ± 0.611
3.679SerGlu: 3.679 ± 1.495
4.244SerPhe: 4.244 ± 1.518
8.206SerGly: 8.206 ± 1.495
1.981SerHis: 1.981 ± 0.706
3.396SerIle: 3.396 ± 0.794
2.83SerLys: 2.83 ± 1.031
8.772SerLeu: 8.772 ± 2.072
1.698SerMet: 1.698 ± 0.513
1.132SerAsn: 1.132 ± 0.595
3.962SerPro: 3.962 ± 1.773
2.83SerGln: 2.83 ± 1.07
5.376SerArg: 5.376 ± 1.241
5.376SerSer: 5.376 ± 1.464
2.264SerThr: 2.264 ± 0.766
6.791SerVal: 6.791 ± 1.414
2.264SerTrp: 2.264 ± 1.165
1.415SerTyr: 1.415 ± 0.564
0.0SerXaa: 0.0 ± 0.0
Thr
3.396ThrAla: 3.396 ± 1.066
1.415ThrCys: 1.415 ± 0.881
2.547ThrAsp: 2.547 ± 0.426
2.547ThrGlu: 2.547 ± 0.567
0.566ThrPhe: 0.566 ± 0.274
3.962ThrGly: 3.962 ± 0.539
0.849ThrHis: 0.849 ± 0.446
4.244ThrIle: 4.244 ± 0.797
4.527ThrLys: 4.527 ± 1.373
4.527ThrLeu: 4.527 ± 1.395
1.415ThrMet: 1.415 ± 0.981
1.415ThrAsn: 1.415 ± 0.443
3.113ThrPro: 3.113 ± 1.216
1.132ThrGln: 1.132 ± 0.334
4.527ThrArg: 4.527 ± 0.541
5.659ThrSer: 5.659 ± 1.749
3.962ThrThr: 3.962 ± 0.233
4.244ThrVal: 4.244 ± 0.833
2.264ThrTrp: 2.264 ± 0.669
1.981ThrTyr: 1.981 ± 0.734
0.0ThrXaa: 0.0 ± 0.0
Val
2.83ValAla: 2.83 ± 0.487
1.698ValCys: 1.698 ± 0.636
3.962ValAsp: 3.962 ± 1.341
3.679ValGlu: 3.679 ± 0.354
2.264ValPhe: 2.264 ± 0.979
4.81ValGly: 4.81 ± 0.897
0.566ValHis: 0.566 ± 0.325
3.679ValIle: 3.679 ± 0.979
2.83ValLys: 2.83 ± 0.882
5.093ValLeu: 5.093 ± 1.404
1.132ValMet: 1.132 ± 1.095
2.83ValAsn: 2.83 ± 0.508
1.415ValPro: 1.415 ± 0.237
1.981ValGln: 1.981 ± 0.469
3.679ValArg: 3.679 ± 0.979
5.093ValSer: 5.093 ± 1.034
3.962ValThr: 3.962 ± 0.973
4.244ValVal: 4.244 ± 1.108
0.283ValTrp: 0.283 ± 0.351
3.113ValTyr: 3.113 ± 0.405
0.0ValXaa: 0.0 ± 0.0
Trp
0.566TrpAla: 0.566 ± 0.325
0.0TrpCys: 0.0 ± 0.0
0.566TrpAsp: 0.566 ± 0.543
1.415TrpGlu: 1.415 ± 0.443
0.566TrpPhe: 0.566 ± 0.297
1.698TrpGly: 1.698 ± 0.571
0.283TrpHis: 0.283 ± 0.149
0.849TrpIle: 0.849 ± 0.401
1.132TrpLys: 1.132 ± 0.375
1.981TrpLeu: 1.981 ± 0.886
0.566TrpMet: 0.566 ± 0.245
1.698TrpAsn: 1.698 ± 0.449
0.283TrpPro: 0.283 ± 0.149
0.0TrpGln: 0.0 ± 0.0
0.566TrpArg: 0.566 ± 0.274
2.547TrpSer: 2.547 ± 0.432
2.83TrpThr: 2.83 ± 0.887
1.415TrpVal: 1.415 ± 0.443
0.0TrpTrp: 0.0 ± 0.0
0.849TrpTyr: 0.849 ± 0.401
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.698TyrAla: 1.698 ± 1.507
0.283TyrCys: 0.283 ± 0.351
1.415TyrAsp: 1.415 ± 0.237
1.698TyrGlu: 1.698 ± 0.567
0.849TyrPhe: 0.849 ± 0.706
1.698TyrGly: 1.698 ± 0.528
1.698TyrHis: 1.698 ± 0.571
1.698TyrIle: 1.698 ± 0.842
3.396TyrLys: 3.396 ± 1.126
2.547TyrLeu: 2.547 ± 0.773
1.415TyrMet: 1.415 ± 0.626
1.698TyrAsn: 1.698 ± 0.316
2.264TyrPro: 2.264 ± 0.649
1.981TyrGln: 1.981 ± 0.687
2.83TyrArg: 2.83 ± 1.226
1.698TyrSer: 1.698 ± 0.264
1.415TyrThr: 1.415 ± 0.64
0.566TyrVal: 0.566 ± 0.325
0.566TyrTrp: 0.566 ± 0.529
0.566TyrTyr: 0.566 ± 0.325
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3535 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski