Amino acid dipepetide frequency for Mycolicibacterium fortuitum (Mycobacterium fortuitum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.807AlaAla: 19.807 ± 0.159	0.959AlaCys: 0.959 ± 0.026	8.515AlaAsp: 8.515 ± 0.066	7.991AlaGlu: 7.991 ± 0.075	3.492AlaPhe: 3.492 ± 0.046	11.918AlaGly: 11.918 ± 0.086	2.563AlaHis: 2.563 ± 0.034	5.259AlaIle: 5.259 ± 0.059	3.148AlaLys: 3.148 ± 0.046	12.907AlaLeu: 12.907 ± 0.091	2.988AlaMet: 2.988 ± 0.048	2.636AlaAsn: 2.636 ± 0.045	6.449AlaPro: 6.449 ± 0.095	4.108AlaGln: 4.108 ± 0.045	8.106AlaArg: 8.106 ± 0.076	5.869AlaSer: 5.869 ± 0.066	7.117AlaThr: 7.117 ± 0.064	11.765AlaVal: 11.765 ± 0.098	1.588AlaTrp: 1.588 ± 0.032	2.324AlaTyr: 2.324 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.047CysAla: 1.047 ± 0.029	0.089CysCys: 0.089 ± 0.007	0.517CysAsp: 0.517 ± 0.016	0.421CysGlu: 0.421 ± 0.015	0.212CysPhe: 0.212 ± 0.01	0.883CysGly: 0.883 ± 0.022	0.181CysHis: 0.181 ± 0.011	0.271CysIle: 0.271 ± 0.013	0.127CysLys: 0.127 ± 0.009	0.654CysLeu: 0.654 ± 0.018	0.132CysMet: 0.132 ± 0.008	0.166CysAsn: 0.166 ± 0.009	0.497CysPro: 0.497 ± 0.02	0.215CysGln: 0.215 ± 0.011	0.548CysArg: 0.548 ± 0.017	0.46CysSer: 0.46 ± 0.016	0.489CysThr: 0.489 ± 0.016	0.636CysVal: 0.636 ± 0.019	0.121CysTrp: 0.121 ± 0.007	0.174CysTyr: 0.174 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.588AspAla: 7.588 ± 0.067	0.433AspCys: 0.433 ± 0.016	4.16AspAsp: 4.16 ± 0.056	4.223AspGlu: 4.223 ± 0.058	1.828AspPhe: 1.828 ± 0.033	5.869AspGly: 5.869 ± 0.063	1.448AspHis: 1.448 ± 0.029	2.655AspIle: 2.655 ± 0.039	1.46AspLys: 1.46 ± 0.029	6.007AspLeu: 6.007 ± 0.06	1.066AspMet: 1.066 ± 0.027	1.344AspAsn: 1.344 ± 0.028	4.393AspPro: 4.393 ± 0.048	1.846AspGln: 1.846 ± 0.036	4.498AspArg: 4.498 ± 0.054	2.974AspSer: 2.974 ± 0.041	3.282AspThr: 3.282 ± 0.042	5.229AspVal: 5.229 ± 0.052	1.005AspTrp: 1.005 ± 0.021	1.441AspTyr: 1.441 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	6.305GluAla: 6.305 ± 0.071	0.359GluCys: 0.359 ± 0.014	2.55GluAsp: 2.55 ± 0.042	2.507GluGlu: 2.507 ± 0.047	1.946GluPhe: 1.946 ± 0.031	3.451GluGly: 3.451 ± 0.047	1.571GluHis: 1.571 ± 0.028	2.646GluIle: 2.646 ± 0.036	1.396GluLys: 1.396 ± 0.029	6.71GluLeu: 6.71 ± 0.063	1.07GluMet: 1.07 ± 0.025	1.206GluAsn: 1.206 ± 0.022	3.096GluPro: 3.096 ± 0.052	2.401GluGln: 2.401 ± 0.037	4.238GluArg: 4.238 ± 0.056	2.824GluSer: 2.824 ± 0.043	2.753GluThr: 2.753 ± 0.037	4.408GluVal: 4.408 ± 0.059	0.748GluTrp: 0.748 ± 0.021	1.208GluTyr: 1.208 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	3.967PheAla: 3.967 ± 0.052	0.316PheCys: 0.316 ± 0.012	2.547PheAsp: 2.547 ± 0.045	1.631PheGlu: 1.631 ± 0.029	1.001PhePhe: 1.001 ± 0.028	3.479PheGly: 3.479 ± 0.04	0.641PheHis: 0.641 ± 0.019	1.158PheIle: 1.158 ± 0.023	0.574PheLys: 0.574 ± 0.017	2.525PheLeu: 2.525 ± 0.036	0.55PheMet: 0.55 ± 0.016	0.788PheAsn: 0.788 ± 0.022	1.446PhePro: 1.446 ± 0.029	0.71PheGln: 0.71 ± 0.018	1.646PheArg: 1.646 ± 0.03	1.826PheSer: 1.826 ± 0.032	2.14PheThr: 2.14 ± 0.031	2.591PheVal: 2.591 ± 0.041	0.48PheTrp: 0.48 ± 0.018	0.75PheTyr: 0.75 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.034GlyAla: 10.034 ± 0.088	0.773GlyCys: 0.773 ± 0.023	4.881GlyAsp: 4.881 ± 0.051	4.432GlyGlu: 4.432 ± 0.051	3.098GlyPhe: 3.098 ± 0.043	7.56GlyGly: 7.56 ± 0.079	2.0GlyHis: 2.0 ± 0.035	4.218GlyIle: 4.218 ± 0.054	2.406GlyLys: 2.406 ± 0.042	8.71GlyLeu: 8.71 ± 0.069	2.222GlyMet: 2.222 ± 0.039	2.014GlyAsn: 2.014 ± 0.035	4.539GlyPro: 4.539 ± 0.05	2.915GlyGln: 2.915 ± 0.04	5.981GlyArg: 5.981 ± 0.055	5.273GlySer: 5.273 ± 0.053	5.378GlyThr: 5.378 ± 0.056	7.519GlyVal: 7.519 ± 0.061	1.702GlyTrp: 1.702 ± 0.031	2.469GlyTyr: 2.469 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	2.353HisAla: 2.353 ± 0.034	0.215HisCys: 0.215 ± 0.01	1.403HisAsp: 1.403 ± 0.033	1.079HisGlu: 1.079 ± 0.023	0.687HisPhe: 0.687 ± 0.02	2.087HisGly: 2.087 ± 0.032	0.698HisHis: 0.698 ± 0.021	0.84HisIle: 0.84 ± 0.022	0.364HisLys: 0.364 ± 0.015	2.126HisLeu: 2.126 ± 0.039	0.377HisMet: 0.377 ± 0.014	0.484HisAsn: 0.484 ± 0.018	1.658HisPro: 1.658 ± 0.032	0.666HisGln: 0.666 ± 0.019	1.889HisArg: 1.889 ± 0.03	1.135HisSer: 1.135 ± 0.026	1.245HisThr: 1.245 ± 0.028	1.693HisVal: 1.693 ± 0.032	0.391HisTrp: 0.391 ± 0.015	0.537HisTyr: 0.537 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.419IleAla: 6.419 ± 0.063	0.404IleCys: 0.404 ± 0.017	3.398IleAsp: 3.398 ± 0.051	2.661IleGlu: 2.661 ± 0.039	1.074IlePhe: 1.074 ± 0.024	4.575IleGly: 4.575 ± 0.055	0.787IleHis: 0.787 ± 0.021	1.547IleIle: 1.547 ± 0.035	0.978IleLys: 0.978 ± 0.02	3.129IleLeu: 3.129 ± 0.039	0.616IleMet: 0.616 ± 0.018	1.145IleAsn: 1.145 ± 0.026	2.433IlePro: 2.433 ± 0.038	0.98IleGln: 0.98 ± 0.024	2.649IleArg: 2.649 ± 0.032	2.431IleSer: 2.431 ± 0.037	2.816IleThr: 2.816 ± 0.041	3.676IleVal: 3.676 ± 0.045	0.516IleTrp: 0.516 ± 0.017	0.866IleTyr: 0.866 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	2.873LysAla: 2.873 ± 0.044	0.133LysCys: 0.133 ± 0.008	1.213LysAsp: 1.213 ± 0.031	1.001LysGlu: 1.001 ± 0.025	0.693LysPhe: 0.693 ± 0.018	1.638LysGly: 1.638 ± 0.036	0.519LysHis: 0.519 ± 0.016	1.107LysIle: 1.107 ± 0.026	0.707LysLys: 0.707 ± 0.028	2.468LysLeu: 2.468 ± 0.039	0.545LysMet: 0.545 ± 0.017	0.561LysAsn: 0.561 ± 0.02	1.583LysPro: 1.583 ± 0.034	0.795LysGln: 0.795 ± 0.023	1.609LysArg: 1.609 ± 0.028	1.31LysSer: 1.31 ± 0.029	1.398LysThr: 1.398 ± 0.028	2.018LysVal: 2.018 ± 0.034	0.342LysTrp: 0.342 ± 0.014	0.511LysTyr: 0.511 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	14.021LeuAla: 14.021 ± 0.087	0.781LeuCys: 0.781 ± 0.021	6.517LeuAsp: 6.517 ± 0.065	4.393LeuGlu: 4.393 ± 0.053	2.71LeuPhe: 2.71 ± 0.037	8.725LeuGly: 8.725 ± 0.069	2.078LeuHis: 2.078 ± 0.036	4.224LeuIle: 4.224 ± 0.05	1.987LeuLys: 1.987 ± 0.037	9.469LeuLeu: 9.469 ± 0.089	1.797LeuMet: 1.797 ± 0.029	2.246LeuAsn: 2.246 ± 0.036	5.776LeuPro: 5.776 ± 0.06	2.673LeuGln: 2.673 ± 0.039	7.203LeuArg: 7.203 ± 0.072	5.792LeuSer: 5.792 ± 0.055	6.458LeuThr: 6.458 ± 0.064	8.344LeuVal: 8.344 ± 0.086	1.228LeuTrp: 1.228 ± 0.027	1.713LeuTyr: 1.713 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.71MetAla: 2.71 ± 0.042	0.181MetCys: 0.181 ± 0.01	0.928MetAsp: 0.928 ± 0.023	0.702MetGlu: 0.702 ± 0.019	0.702MetPhe: 0.702 ± 0.021	1.533MetGly: 1.533 ± 0.028	0.413MetHis: 0.413 ± 0.016	0.926MetIle: 0.926 ± 0.021	0.504MetLys: 0.504 ± 0.019	2.163MetLeu: 2.163 ± 0.033	0.459MetMet: 0.459 ± 0.016	0.529MetAsn: 0.529 ± 0.016	1.318MetPro: 1.318 ± 0.025	0.583MetGln: 0.583 ± 0.017	1.548MetArg: 1.548 ± 0.032	1.622MetSer: 1.622 ± 0.031	1.852MetThr: 1.852 ± 0.028	1.768MetVal: 1.768 ± 0.029	0.267MetTrp: 0.267 ± 0.011	0.358MetTyr: 0.358 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.67AsnAla: 2.67 ± 0.035	0.197AsnCys: 0.197 ± 0.011	1.264AsnAsp: 1.264 ± 0.029	1.04AsnGlu: 1.04 ± 0.026	0.71AsnPhe: 0.71 ± 0.02	2.119AsnGly: 2.119 ± 0.037	0.499AsnHis: 0.499 ± 0.017	0.978AsnIle: 0.978 ± 0.025	0.539AsnLys: 0.539 ± 0.019	2.131AsnLeu: 2.131 ± 0.037	0.463AsnMet: 0.463 ± 0.014	0.592AsnAsn: 0.592 ± 0.019	1.844AsnPro: 1.844 ± 0.035	0.681AsnGln: 0.681 ± 0.018	1.634AsnArg: 1.634 ± 0.031	1.252AsnSer: 1.252 ± 0.025	1.403AsnThr: 1.403 ± 0.026	1.818AsnVal: 1.818 ± 0.033	0.409AsnTrp: 0.409 ± 0.014	0.593AsnTyr: 0.593 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	7.422ProAla: 7.422 ± 0.093	0.296ProCys: 0.296 ± 0.012	4.441ProAsp: 4.441 ± 0.043	3.943ProGlu: 3.943 ± 0.048	1.69ProPhe: 1.69 ± 0.028	5.665ProGly: 5.665 ± 0.065	1.197ProHis: 1.197 ± 0.027	2.193ProIle: 2.193 ± 0.033	1.361ProLys: 1.361 ± 0.027	4.779ProLeu: 4.779 ± 0.051	1.261ProMet: 1.261 ± 0.027	1.296ProAsn: 1.296 ± 0.027	3.484ProPro: 3.484 ± 0.074	1.882ProGln: 1.882 ± 0.037	3.281ProArg: 3.281 ± 0.046	3.122ProSer: 3.122 ± 0.043	3.45ProThr: 3.45 ± 0.044	5.186ProVal: 5.186 ± 0.057	0.875ProTrp: 0.875 ± 0.021	1.218ProTyr: 1.218 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.786GlnAla: 3.786 ± 0.047	0.221GlnCys: 0.221 ± 0.012	1.267GlnAsp: 1.267 ± 0.025	1.154GlnGlu: 1.154 ± 0.023	1.05GlnPhe: 1.05 ± 0.022	2.03GlnGly: 2.03 ± 0.035	0.755GlnHis: 0.755 ± 0.02	1.625GlnIle: 1.625 ± 0.03	0.699GlnLys: 0.699 ± 0.019	3.653GlnLeu: 3.653 ± 0.045	0.76GlnMet: 0.76 ± 0.02	0.648GlnAsn: 0.648 ± 0.02	1.905GlnPro: 1.905 ± 0.034	1.38GlnGln: 1.38 ± 0.034	2.788GlnArg: 2.788 ± 0.041	1.557GlnSer: 1.557 ± 0.033	1.658GlnThr: 1.658 ± 0.028	2.593GlnVal: 2.593 ± 0.045	0.634GlnTrp: 0.634 ± 0.02	0.673GlnTyr: 0.673 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	7.861ArgAla: 7.861 ± 0.073	0.543ArgCys: 0.543 ± 0.016	4.126ArgAsp: 4.126 ± 0.052	3.786ArgGlu: 3.786 ± 0.046	2.378ArgPhe: 2.378 ± 0.035	4.911ArgGly: 4.911 ± 0.05	1.72ArgHis: 1.72 ± 0.036	3.404ArgIle: 3.404 ± 0.046	1.599ArgLys: 1.599 ± 0.034	7.192ArgLeu: 7.192 ± 0.078	1.759ArgMet: 1.759 ± 0.029	1.696ArgAsn: 1.696 ± 0.033	3.752ArgPro: 3.752 ± 0.047	2.334ArgGln: 2.334 ± 0.035	6.083ArgArg: 6.083 ± 0.069	3.959ArgSer: 3.959 ± 0.049	4.099ArgThr: 4.099 ± 0.048	5.344ArgVal: 5.344 ± 0.059	1.328ArgTrp: 1.328 ± 0.024	1.882ArgTyr: 1.882 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	7.217SerAla: 7.217 ± 0.068	0.405SerCys: 0.405 ± 0.015	3.299SerAsp: 3.299 ± 0.04	2.723SerGlu: 2.723 ± 0.043	1.665SerPhe: 1.665 ± 0.027	5.727SerGly: 5.727 ± 0.054	1.058SerHis: 1.058 ± 0.023	2.187SerIle: 2.187 ± 0.035	1.247SerLys: 1.247 ± 0.03	4.807SerLeu: 4.807 ± 0.05	1.37SerMet: 1.37 ± 0.026	1.153SerAsn: 1.153 ± 0.027	3.082SerPro: 3.082 ± 0.038	1.529SerGln: 1.529 ± 0.028	3.551SerArg: 3.551 ± 0.046	3.237SerSer: 3.237 ± 0.048	3.461SerThr: 3.461 ± 0.043	4.717SerVal: 4.717 ± 0.049	0.942SerTrp: 0.942 ± 0.023	1.289SerTyr: 1.289 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	8.001ThrAla: 8.001 ± 0.079	0.415ThrCys: 0.415 ± 0.014	3.872ThrAsp: 3.872 ± 0.044	3.354ThrGlu: 3.354 ± 0.04	1.878ThrPhe: 1.878 ± 0.033	5.886ThrGly: 5.886 ± 0.055	1.181ThrHis: 1.181 ± 0.023	2.449ThrIle: 2.449 ± 0.04	1.357ThrLys: 1.357 ± 0.029	5.562ThrLeu: 5.562 ± 0.054	1.302ThrMet: 1.302 ± 0.029	1.253ThrAsn: 1.253 ± 0.028	3.849ThrPro: 3.849 ± 0.046	1.563ThrGln: 1.563 ± 0.029	3.561ThrArg: 3.561 ± 0.046	3.124ThrSer: 3.124 ± 0.041	3.979ThrThr: 3.979 ± 0.059	5.991ThrVal: 5.991 ± 0.054	0.854ThrTrp: 0.854 ± 0.02	1.328ThrTyr: 1.328 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	11.429ValAla: 11.429 ± 0.093	0.724ValCys: 0.724 ± 0.02	5.605ValAsp: 5.605 ± 0.065	4.607ValGlu: 4.607 ± 0.058	2.617ValPhe: 2.617 ± 0.039	6.973ValGly: 6.973 ± 0.062	1.793ValHis: 1.793 ± 0.029	4.022ValIle: 4.022 ± 0.047	1.82ValLys: 1.82 ± 0.034	8.988ValLeu: 8.988 ± 0.074	1.638ValMet: 1.638 ± 0.034	2.117ValAsn: 2.117 ± 0.036	4.768ValPro: 4.768 ± 0.057	2.176ValGln: 2.176 ± 0.033	5.756ValArg: 5.756 ± 0.053	4.802ValSer: 4.802 ± 0.046	5.628ValThr: 5.628 ± 0.062	8.347ValVal: 8.347 ± 0.079	1.074ValTrp: 1.074 ± 0.025	1.572ValTyr: 1.572 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.578TrpAla: 1.578 ± 0.03	0.15TrpCys: 0.15 ± 0.009	0.808TrpAsp: 0.808 ± 0.023	0.666TrpGlu: 0.666 ± 0.021	0.547TrpPhe: 0.547 ± 0.017	1.031TrpGly: 1.031 ± 0.027	0.37TrpHis: 0.37 ± 0.014	0.71TrpIle: 0.71 ± 0.021	0.35TrpLys: 0.35 ± 0.015	1.741TrpLeu: 1.741 ± 0.031	0.373TrpMet: 0.373 ± 0.012	0.434TrpAsn: 0.434 ± 0.015	0.875TrpPro: 0.875 ± 0.021	0.675TrpGln: 0.675 ± 0.021	1.233TrpArg: 1.233 ± 0.029	0.947TrpSer: 0.947 ± 0.022	0.934TrpThr: 0.934 ± 0.023	1.133TrpVal: 1.133 ± 0.025	0.351TrpTrp: 0.351 ± 0.016	0.349TrpTyr: 0.349 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.422TyrAla: 2.422 ± 0.043	0.247TyrCys: 0.247 ± 0.013	1.436TyrAsp: 1.436 ± 0.028	1.08TyrGlu: 1.08 ± 0.024	0.788TyrPhe: 0.788 ± 0.02	2.063TyrGly: 2.063 ± 0.031	0.456TyrHis: 0.456 ± 0.016	0.68TyrIle: 0.68 ± 0.017	0.401TyrLys: 0.401 ± 0.016	2.417TyrLeu: 2.417 ± 0.04	0.315TyrMet: 0.315 ± 0.015	0.529TyrAsn: 0.529 ± 0.017	1.296TyrPro: 1.296 ± 0.025	0.726TyrGln: 0.726 ± 0.02	1.953TyrArg: 1.953 ± 0.034	1.149TyrSer: 1.149 ± 0.022	1.218TyrThr: 1.218 ± 0.025	1.679TyrVal: 1.679 ± 0.03	0.401TyrTrp: 0.401 ± 0.017	0.511TyrTyr: 0.511 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6012 proteins (1901592 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---