Amino acid dipepetide frequency for Oidium neolycopersici

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.899AlaAla: 4.899 ± 0.056	0.87AlaCys: 0.87 ± 0.017	2.762AlaAsp: 2.762 ± 0.034	3.83AlaGlu: 3.83 ± 0.043	2.473AlaPhe: 2.473 ± 0.033	3.543AlaGly: 3.543 ± 0.039	1.334AlaHis: 1.334 ± 0.021	4.316AlaIle: 4.316 ± 0.044	3.864AlaLys: 3.864 ± 0.042	6.228AlaLeu: 6.228 ± 0.054	1.325AlaMet: 1.325 ± 0.021	2.7AlaAsn: 2.7 ± 0.03	2.831AlaPro: 2.831 ± 0.035	2.598AlaGln: 2.598 ± 0.031	3.593AlaArg: 3.593 ± 0.037	5.647AlaSer: 5.647 ± 0.041	3.775AlaThr: 3.775 ± 0.041	3.486AlaVal: 3.486 ± 0.038	0.768AlaTrp: 0.768 ± 0.017	1.713AlaTyr: 1.713 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.767CysAla: 0.767 ± 0.019	0.245CysCys: 0.245 ± 0.009	0.705CysAsp: 0.705 ± 0.016	0.764CysGlu: 0.764 ± 0.016	0.586CysPhe: 0.586 ± 0.015	0.877CysGly: 0.877 ± 0.02	0.363CysHis: 0.363 ± 0.012	0.854CysIle: 0.854 ± 0.016	0.742CysLys: 0.742 ± 0.017	1.391CysLeu: 1.391 ± 0.023	0.271CysMet: 0.271 ± 0.009	0.611CysAsn: 0.611 ± 0.015	0.598CysPro: 0.598 ± 0.014	0.536CysGln: 0.536 ± 0.012	0.738CysArg: 0.738 ± 0.018	1.151CysSer: 1.151 ± 0.02	0.685CysThr: 0.685 ± 0.014	0.706CysVal: 0.706 ± 0.016	0.177CysTrp: 0.177 ± 0.007	0.405CysTyr: 0.405 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	3.104AspAla: 3.104 ± 0.034	0.688AspCys: 0.688 ± 0.016	3.713AspAsp: 3.713 ± 0.045	4.417AspGlu: 4.417 ± 0.046	2.407AspPhe: 2.407 ± 0.029	3.052AspGly: 3.052 ± 0.036	1.146AspHis: 1.146 ± 0.021	3.897AspIle: 3.897 ± 0.041	2.973AspLys: 2.973 ± 0.034	5.236AspLeu: 5.236 ± 0.042	1.092AspMet: 1.092 ± 0.02	2.473AspAsn: 2.473 ± 0.033	2.583AspPro: 2.583 ± 0.031	2.079AspGln: 2.079 ± 0.026	2.638AspArg: 2.638 ± 0.029	4.656AspSer: 4.656 ± 0.05	2.764AspThr: 2.764 ± 0.029	3.076AspVal: 3.076 ± 0.035	0.681AspTrp: 0.681 ± 0.015	1.626AspTyr: 1.626 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	4.291GluAla: 4.291 ± 0.04	0.703GluCys: 0.703 ± 0.018	4.01GluAsp: 4.01 ± 0.045	5.423GluGlu: 5.423 ± 0.068	2.289GluPhe: 2.289 ± 0.026	2.991GluGly: 2.991 ± 0.034	1.155GluHis: 1.155 ± 0.018	4.85GluIle: 4.85 ± 0.042	5.213GluLys: 5.213 ± 0.051	5.619GluLeu: 5.619 ± 0.045	1.412GluMet: 1.412 ± 0.024	4.087GluAsn: 4.087 ± 0.04	2.173GluPro: 2.173 ± 0.032	2.333GluGln: 2.333 ± 0.033	3.708GluArg: 3.708 ± 0.04	5.295GluSer: 5.295 ± 0.044	3.595GluThr: 3.595 ± 0.04	3.447GluVal: 3.447 ± 0.036	0.802GluTrp: 0.802 ± 0.016	1.822GluTyr: 1.822 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	2.407PheAla: 2.407 ± 0.034	0.609PheCys: 0.609 ± 0.015	2.306PheAsp: 2.306 ± 0.03	2.52PheGlu: 2.52 ± 0.029	1.658PhePhe: 1.658 ± 0.029	2.481PheGly: 2.481 ± 0.034	0.947PheHis: 0.947 ± 0.018	2.358PheIle: 2.358 ± 0.031	2.11PheLys: 2.11 ± 0.026	3.738PheLeu: 3.738 ± 0.042	0.755PheMet: 0.755 ± 0.018	1.898PheAsn: 1.898 ± 0.026	1.895PhePro: 1.895 ± 0.026	1.581PheGln: 1.581 ± 0.02	2.038PheArg: 2.038 ± 0.029	3.726PheSer: 3.726 ± 0.036	2.215PheThr: 2.215 ± 0.03	2.126PheVal: 2.126 ± 0.028	0.535PheTrp: 0.535 ± 0.015	1.235PheTyr: 1.235 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	3.238GlyAla: 3.238 ± 0.039	0.752GlyCys: 0.752 ± 0.017	2.754GlyAsp: 2.754 ± 0.03	2.983GlyGlu: 2.983 ± 0.035	2.406GlyPhe: 2.406 ± 0.028	3.756GlyGly: 3.756 ± 0.06	1.307GlyHis: 1.307 ± 0.02	3.922GlyIle: 3.922 ± 0.036	3.579GlyLys: 3.579 ± 0.037	5.077GlyLeu: 5.077 ± 0.046	1.173GlyMet: 1.173 ± 0.02	2.73GlyAsn: 2.73 ± 0.034	2.218GlyPro: 2.218 ± 0.03	1.98GlyGln: 1.98 ± 0.029	3.153GlyArg: 3.153 ± 0.034	4.735GlySer: 4.735 ± 0.042	3.116GlyThr: 3.116 ± 0.033	3.183GlyVal: 3.183 ± 0.04	0.833GlyTrp: 0.833 ± 0.018	1.811GlyTyr: 1.811 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.229HisAla: 1.229 ± 0.02	0.321HisCys: 0.321 ± 0.01	1.2HisAsp: 1.2 ± 0.019	1.392HisGlu: 1.392 ± 0.024	0.904HisPhe: 0.904 ± 0.014	1.28HisGly: 1.28 ± 0.023	0.682HisHis: 0.682 ± 0.016	1.519HisIle: 1.519 ± 0.022	1.233HisLys: 1.233 ± 0.02	2.199HisLeu: 2.199 ± 0.028	0.407HisMet: 0.407 ± 0.013	1.114HisAsn: 1.114 ± 0.022	1.289HisPro: 1.289 ± 0.02	1.096HisGln: 1.096 ± 0.02	1.299HisArg: 1.299 ± 0.023	1.954HisSer: 1.954 ± 0.029	1.168HisThr: 1.168 ± 0.019	1.191HisVal: 1.191 ± 0.021	0.256HisTrp: 0.256 ± 0.01	0.708HisTyr: 0.708 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	4.124IleAla: 4.124 ± 0.046	1.004IleCys: 1.004 ± 0.022	3.887IleAsp: 3.887 ± 0.037	4.385IleGlu: 4.385 ± 0.04	2.811IlePhe: 2.811 ± 0.032	3.5IleGly: 3.5 ± 0.04	1.459IleHis: 1.459 ± 0.024	4.226IleIle: 4.226 ± 0.049	4.069IleLys: 4.069 ± 0.039	6.329IleLeu: 6.329 ± 0.061	1.253IleMet: 1.253 ± 0.022	3.337IleAsn: 3.337 ± 0.033	3.568IlePro: 3.568 ± 0.031	2.668IleGln: 2.668 ± 0.033	3.466IleArg: 3.466 ± 0.035	6.649IleSer: 6.649 ± 0.054	3.681IleThr: 3.681 ± 0.034	3.457IleVal: 3.457 ± 0.04	0.833IleTrp: 0.833 ± 0.019	1.956IleTyr: 1.956 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.107LysAla: 4.107 ± 0.039	0.754LysCys: 0.754 ± 0.015	3.463LysAsp: 3.463 ± 0.035	4.427LysGlu: 4.427 ± 0.049	2.334LysPhe: 2.334 ± 0.034	2.952LysGly: 2.952 ± 0.03	1.263LysHis: 1.263 ± 0.02	4.65LysIle: 4.65 ± 0.045	5.398LysLys: 5.398 ± 0.063	5.727LysLeu: 5.727 ± 0.043	1.335LysMet: 1.335 ± 0.023	3.807LysAsn: 3.807 ± 0.042	2.864LysPro: 2.864 ± 0.029	2.28LysGln: 2.28 ± 0.03	3.915LysArg: 3.915 ± 0.04	5.886LysSer: 5.886 ± 0.056	3.661LysThr: 3.661 ± 0.035	3.287LysVal: 3.287 ± 0.032	0.735LysTrp: 0.735 ± 0.017	2.028LysTyr: 2.028 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	6.278LeuAla: 6.278 ± 0.05	1.296LeuCys: 1.296 ± 0.022	5.228LeuAsp: 5.228 ± 0.046	6.211LeuGlu: 6.211 ± 0.051	3.408LeuPhe: 3.408 ± 0.04	5.041LeuGly: 5.041 ± 0.051	2.125LeuHis: 2.125 ± 0.024	5.494LeuIle: 5.494 ± 0.053	5.952LeuLys: 5.952 ± 0.041	8.522LeuLeu: 8.522 ± 0.076	1.786LeuMet: 1.786 ± 0.026	4.614LeuAsn: 4.614 ± 0.033	5.008LeuPro: 5.008 ± 0.048	4.064LeuGln: 4.064 ± 0.046	5.532LeuArg: 5.532 ± 0.04	8.643LeuSer: 8.643 ± 0.063	5.026LeuThr: 5.026 ± 0.043	4.899LeuVal: 4.899 ± 0.049	1.054LeuTrp: 1.054 ± 0.02	2.464LeuTyr: 2.464 ± 0.031	0.0LeuXaa: 0.0 ± 0.0
Met	1.661MetAla: 1.661 ± 0.025	0.24MetCys: 0.24 ± 0.01	1.068MetAsp: 1.068 ± 0.02	1.271MetGlu: 1.271 ± 0.022	0.653MetPhe: 0.653 ± 0.015	1.182MetGly: 1.182 ± 0.021	0.369MetHis: 0.369 ± 0.012	1.288MetIle: 1.288 ± 0.019	1.341MetLys: 1.341 ± 0.02	1.648MetLeu: 1.648 ± 0.022	0.511MetMet: 0.511 ± 0.015	1.043MetAsn: 1.043 ± 0.02	0.988MetPro: 0.988 ± 0.019	0.744MetGln: 0.744 ± 0.015	1.118MetArg: 1.118 ± 0.021	1.881MetSer: 1.881 ± 0.028	1.241MetThr: 1.241 ± 0.022	1.08MetVal: 1.08 ± 0.019	0.205MetTrp: 0.205 ± 0.009	0.485MetTyr: 0.485 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.724AsnAla: 2.724 ± 0.028	0.681AsnCys: 0.681 ± 0.013	2.795AsnAsp: 2.795 ± 0.028	3.305AsnGlu: 3.305 ± 0.035	2.302AsnPhe: 2.302 ± 0.027	2.88AsnGly: 2.88 ± 0.038	1.282AsnHis: 1.282 ± 0.022	3.688AsnIle: 3.688 ± 0.039	2.945AsnLys: 2.945 ± 0.034	5.072AsnLeu: 5.072 ± 0.045	1.035AsnMet: 1.035 ± 0.018	2.918AsnAsn: 2.918 ± 0.038	2.678AsnPro: 2.678 ± 0.032	2.234AsnGln: 2.234 ± 0.029	2.539AsnArg: 2.539 ± 0.029	5.277AsnSer: 5.277 ± 0.05	2.985AsnThr: 2.985 ± 0.031	2.641AsnVal: 2.641 ± 0.03	0.619AsnTrp: 0.619 ± 0.013	1.642AsnTyr: 1.642 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	2.825ProAla: 2.825 ± 0.034	0.517ProCys: 0.517 ± 0.014	2.437ProAsp: 2.437 ± 0.034	3.163ProGlu: 3.163 ± 0.037	1.832ProPhe: 1.832 ± 0.023	2.572ProGly: 2.572 ± 0.035	1.104ProHis: 1.104 ± 0.019	3.283ProIle: 3.283 ± 0.035	3.119ProLys: 3.119 ± 0.032	4.438ProLeu: 4.438 ± 0.038	0.852ProMet: 0.852 ± 0.017	2.598ProAsn: 2.598 ± 0.033	3.403ProPro: 3.403 ± 0.054	2.081ProGln: 2.081 ± 0.029	2.593ProArg: 2.593 ± 0.032	5.158ProSer: 5.158 ± 0.051	3.216ProThr: 3.216 ± 0.036	2.619ProVal: 2.619 ± 0.031	0.526ProTrp: 0.526 ± 0.013	1.399ProTyr: 1.399 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	2.689GlnAla: 2.689 ± 0.035	0.448GlnCys: 0.448 ± 0.011	2.072GlnAsp: 2.072 ± 0.025	2.614GlnGlu: 2.614 ± 0.034	1.391GlnPhe: 1.391 ± 0.022	1.89GlnGly: 1.89 ± 0.026	0.921GlnHis: 0.921 ± 0.019	2.853GlnIle: 2.853 ± 0.03	2.948GlnLys: 2.948 ± 0.035	3.551GlnLeu: 3.551 ± 0.041	0.821GlnMet: 0.821 ± 0.016	2.599GlnAsn: 2.599 ± 0.031	1.863GlnPro: 1.863 ± 0.027	2.181GlnGln: 2.181 ± 0.058	2.426GlnArg: 2.426 ± 0.029	3.605GlnSer: 3.605 ± 0.039	2.297GlnThr: 2.297 ± 0.029	2.138GlnVal: 2.138 ± 0.027	0.437GlnTrp: 0.437 ± 0.011	1.236GlnTyr: 1.236 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	3.488ArgAla: 3.488 ± 0.037	0.738ArgCys: 0.738 ± 0.017	2.997ArgAsp: 2.997 ± 0.037	3.664ArgGlu: 3.664 ± 0.042	2.068ArgPhe: 2.068 ± 0.026	2.966ArgGly: 2.966 ± 0.036	1.325ArgHis: 1.325 ± 0.02	3.524ArgIle: 3.524 ± 0.035	4.204ArgLys: 4.204 ± 0.043	5.133ArgLeu: 5.133 ± 0.051	1.167ArgMet: 1.167 ± 0.021	2.988ArgAsn: 2.988 ± 0.029	2.611ArgPro: 2.611 ± 0.031	2.417ArgGln: 2.417 ± 0.032	4.075ArgArg: 4.075 ± 0.045	4.795ArgSer: 4.795 ± 0.048	2.838ArgThr: 2.838 ± 0.032	2.854ArgVal: 2.854 ± 0.031	0.688ArgTrp: 0.688 ± 0.014	1.616ArgTyr: 1.616 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	4.937SerAla: 4.937 ± 0.044	1.17SerCys: 1.17 ± 0.024	4.687SerAsp: 4.687 ± 0.05	5.312SerGlu: 5.312 ± 0.045	3.559SerPhe: 3.559 ± 0.035	4.985SerGly: 4.985 ± 0.05	2.205SerHis: 2.205 ± 0.032	6.19SerIle: 6.19 ± 0.051	5.968SerLys: 5.968 ± 0.05	8.668SerLeu: 8.668 ± 0.064	1.818SerMet: 1.818 ± 0.027	5.213SerAsn: 5.213 ± 0.047	5.141SerPro: 5.141 ± 0.06	4.047SerGln: 4.047 ± 0.041	5.236SerArg: 5.236 ± 0.053	10.71SerSer: 10.71 ± 0.103	5.922SerThr: 5.922 ± 0.053	4.411SerVal: 4.411 ± 0.038	1.014SerTrp: 1.014 ± 0.021	2.498SerTyr: 2.498 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	3.651ThrAla: 3.651 ± 0.035	0.775ThrCys: 0.775 ± 0.015	2.642ThrAsp: 2.642 ± 0.031	3.365ThrGlu: 3.365 ± 0.033	2.151ThrPhe: 2.151 ± 0.026	3.307ThrGly: 3.307 ± 0.031	1.277ThrHis: 1.277 ± 0.021	3.717ThrIle: 3.717 ± 0.038	3.519ThrLys: 3.519 ± 0.032	5.202ThrLeu: 5.202 ± 0.045	1.053ThrMet: 1.053 ± 0.019	2.891ThrAsn: 2.891 ± 0.032	3.448ThrPro: 3.448 ± 0.041	2.285ThrGln: 2.285 ± 0.028	2.954ThrArg: 2.954 ± 0.032	5.974ThrSer: 5.974 ± 0.051	3.88ThrThr: 3.88 ± 0.045	3.105ThrVal: 3.105 ± 0.033	0.639ThrTrp: 0.639 ± 0.015	1.615ThrTyr: 1.615 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	3.625ValAla: 3.625 ± 0.04	0.729ValCys: 0.729 ± 0.016	3.142ValAsp: 3.142 ± 0.034	3.619ValGlu: 3.619 ± 0.045	2.132ValPhe: 2.132 ± 0.027	3.031ValGly: 3.031 ± 0.037	1.121ValHis: 1.121 ± 0.02	3.424ValIle: 3.424 ± 0.041	3.334ValLys: 3.334 ± 0.037	4.79ValLeu: 4.79 ± 0.042	1.105ValMet: 1.105 ± 0.018	2.546ValAsn: 2.546 ± 0.026	2.705ValPro: 2.705 ± 0.032	2.033ValGln: 2.033 ± 0.029	2.771ValArg: 2.771 ± 0.035	4.529ValSer: 4.529 ± 0.045	3.127ValThr: 3.127 ± 0.034	3.156ValVal: 3.156 ± 0.037	0.634ValTrp: 0.634 ± 0.015	1.436ValTyr: 1.436 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	0.798TrpAla: 0.798 ± 0.016	0.19TrpCys: 0.19 ± 0.007	0.731TrpAsp: 0.731 ± 0.016	0.738TrpGlu: 0.738 ± 0.014	0.446TrpPhe: 0.446 ± 0.014	0.656TrpGly: 0.656 ± 0.017	0.274TrpHis: 0.274 ± 0.009	0.813TrpIle: 0.813 ± 0.018	0.837TrpLys: 0.837 ± 0.015	1.121TrpLeu: 1.121 ± 0.019	0.278TrpMet: 0.278 ± 0.01	0.636TrpAsn: 0.636 ± 0.016	0.477TrpPro: 0.477 ± 0.014	0.462TrpGln: 0.462 ± 0.013	0.742TrpArg: 0.742 ± 0.016	0.91TrpSer: 0.91 ± 0.02	0.704TrpThr: 0.704 ± 0.018	0.638TrpVal: 0.638 ± 0.013	0.218TrpTrp: 0.218 ± 0.009	0.341TrpTyr: 0.341 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.709TyrAla: 1.709 ± 0.023	0.443TyrCys: 0.443 ± 0.011	1.703TyrAsp: 1.703 ± 0.026	1.817TyrGlu: 1.817 ± 0.024	1.328TyrPhe: 1.328 ± 0.022	1.763TyrGly: 1.763 ± 0.029	0.783TyrHis: 0.783 ± 0.017	1.792TyrIle: 1.792 ± 0.028	1.524TyrLys: 1.524 ± 0.024	2.953TyrLeu: 2.953 ± 0.03	0.569TyrMet: 0.569 ± 0.014	1.438TyrAsn: 1.438 ± 0.022	1.394TyrPro: 1.394 ± 0.025	1.282TyrGln: 1.282 ± 0.025	1.626TyrArg: 1.626 ± 0.023	2.511TyrSer: 2.511 ± 0.03	1.559TyrThr: 1.559 ± 0.024	1.487TyrVal: 1.487 ± 0.023	0.355TyrTrp: 0.355 ± 0.013	0.968TyrTyr: 0.968 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.004XaaXaa: 0.004 ± 0.002

Statistics based on 6847 proteins (3086985 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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