Amino acid dipepetide frequency for Polar bear mastadenovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.496AlaAla: 4.496 ± 0.852
0.749AlaCys: 0.749 ± 0.296
3.247AlaAsp: 3.247 ± 0.602
1.624AlaGlu: 1.624 ± 0.521
2.498AlaPhe: 2.498 ± 0.675
3.372AlaGly: 3.372 ± 0.636
1.374AlaHis: 1.374 ± 0.348
3.372AlaIle: 3.372 ± 0.535
2.997AlaLys: 2.997 ± 0.798
7.369AlaLeu: 7.369 ± 1.083
1.873AlaMet: 1.873 ± 0.579
3.247AlaAsn: 3.247 ± 0.741
4.371AlaPro: 4.371 ± 0.727
1.624AlaGln: 1.624 ± 0.361
2.498AlaArg: 2.498 ± 0.539
3.622AlaSer: 3.622 ± 0.607
3.247AlaThr: 3.247 ± 0.608
3.747AlaVal: 3.747 ± 0.541
0.874AlaTrp: 0.874 ± 0.315
2.373AlaTyr: 2.373 ± 0.47
0.0AlaXaa: 0.0 ± 0.0
Cys
0.999CysAla: 0.999 ± 0.348
0.749CysCys: 0.749 ± 0.413
0.999CysAsp: 0.999 ± 0.335
0.999CysGlu: 0.999 ± 0.288
0.624CysPhe: 0.624 ± 0.263
0.624CysGly: 0.624 ± 0.243
0.624CysHis: 0.624 ± 0.263
0.375CysIle: 0.375 ± 0.243
0.624CysLys: 0.624 ± 0.287
2.123CysLeu: 2.123 ± 0.651
0.375CysMet: 0.375 ± 0.189
1.374CysAsn: 1.374 ± 0.445
1.249CysPro: 1.249 ± 0.34
0.375CysGln: 0.375 ± 0.208
0.624CysArg: 0.624 ± 0.307
1.748CysSer: 1.748 ± 0.591
0.624CysThr: 0.624 ± 0.307
0.999CysVal: 0.999 ± 0.396
0.125CysTrp: 0.125 ± 0.109
0.874CysTyr: 0.874 ± 0.358
0.0CysXaa: 0.0 ± 0.0
Asp
2.872AspAla: 2.872 ± 0.6
0.375AspCys: 0.375 ± 0.235
3.747AspAsp: 3.747 ± 0.507
4.496AspGlu: 4.496 ± 0.797
2.373AspPhe: 2.373 ± 0.555
3.247AspGly: 3.247 ± 0.844
1.374AspHis: 1.374 ± 0.378
2.373AspIle: 2.373 ± 0.452
2.623AspLys: 2.623 ± 0.436
3.997AspLeu: 3.997 ± 0.876
2.123AspMet: 2.123 ± 0.494
2.248AspAsn: 2.248 ± 0.348
3.497AspPro: 3.497 ± 0.654
1.249AspGln: 1.249 ± 0.34
3.497AspArg: 3.497 ± 0.677
5.37AspSer: 5.37 ± 1.098
2.623AspThr: 2.623 ± 0.532
3.997AspVal: 3.997 ± 0.905
0.749AspTrp: 0.749 ± 0.295
2.373AspTyr: 2.373 ± 0.473
0.0AspXaa: 0.0 ± 0.0
Glu
2.872GluAla: 2.872 ± 0.614
0.999GluCys: 0.999 ± 0.434
4.371GluAsp: 4.371 ± 0.541
5.37GluGlu: 5.37 ± 0.914
2.248GluPhe: 2.248 ± 0.526
4.746GluGly: 4.746 ± 0.708
1.499GluHis: 1.499 ± 0.388
3.872GluIle: 3.872 ± 0.698
2.623GluLys: 2.623 ± 0.694
5.121GluLeu: 5.121 ± 1.04
1.748GluMet: 1.748 ± 0.497
3.747GluAsn: 3.747 ± 0.589
2.373GluPro: 2.373 ± 0.644
1.748GluGln: 1.748 ± 0.507
2.748GluArg: 2.748 ± 0.592
2.872GluSer: 2.872 ± 0.527
4.246GluThr: 4.246 ± 0.712
3.497GluVal: 3.497 ± 0.509
0.5GluTrp: 0.5 ± 0.18
1.124GluTyr: 1.124 ± 0.242
0.0GluXaa: 0.0 ± 0.0
Phe
2.373PheAla: 2.373 ± 0.472
0.749PheCys: 0.749 ± 0.306
2.997PheAsp: 2.997 ± 0.556
2.498PheGlu: 2.498 ± 0.523
2.748PhePhe: 2.748 ± 0.425
1.249PheGly: 1.249 ± 0.371
1.374PheHis: 1.374 ± 0.327
2.623PheIle: 2.623 ± 0.674
2.498PheLys: 2.498 ± 0.521
5.745PheLeu: 5.745 ± 0.834
1.499PheMet: 1.499 ± 0.361
2.248PheAsn: 2.248 ± 0.438
2.498PhePro: 2.498 ± 0.456
2.123PheGln: 2.123 ± 0.451
3.247PheArg: 3.247 ± 0.439
3.622PheSer: 3.622 ± 0.365
2.123PheThr: 2.123 ± 0.407
2.123PheVal: 2.123 ± 0.402
0.125PheTrp: 0.125 ± 0.131
1.624PheTyr: 1.624 ± 0.301
0.0PheXaa: 0.0 ± 0.0
Gly
4.121GlyAla: 4.121 ± 0.981
0.749GlyCys: 0.749 ± 0.443
2.748GlyAsp: 2.748 ± 0.637
3.247GlyGlu: 3.247 ± 0.594
2.872GlyPhe: 2.872 ± 0.615
3.122GlyGly: 3.122 ± 1.026
2.123GlyHis: 2.123 ± 0.429
3.372GlyIle: 3.372 ± 0.583
2.872GlyLys: 2.872 ± 0.759
5.121GlyLeu: 5.121 ± 1.082
0.874GlyMet: 0.874 ± 0.212
4.496GlyAsn: 4.496 ± 0.901
2.123GlyPro: 2.123 ± 0.442
2.248GlyGln: 2.248 ± 0.527
3.497GlyArg: 3.497 ± 0.608
3.372GlySer: 3.372 ± 0.611
2.623GlyThr: 2.623 ± 0.645
4.621GlyVal: 4.621 ± 0.968
0.624GlyTrp: 0.624 ± 0.262
1.624GlyTyr: 1.624 ± 0.434
0.0GlyXaa: 0.0 ± 0.0
His
1.249HisAla: 1.249 ± 0.306
0.749HisCys: 0.749 ± 0.317
0.749HisAsp: 0.749 ± 0.228
0.624HisGlu: 0.624 ± 0.278
0.999HisPhe: 0.999 ± 0.529
1.249HisGly: 1.249 ± 0.394
0.375HisHis: 0.375 ± 0.146
1.499HisIle: 1.499 ± 0.251
1.124HisLys: 1.124 ± 0.348
3.122HisLeu: 3.122 ± 0.619
0.749HisMet: 0.749 ± 0.306
1.624HisAsn: 1.624 ± 0.518
2.248HisPro: 2.248 ± 0.57
0.5HisGln: 0.5 ± 0.191
1.748HisArg: 1.748 ± 0.613
1.249HisSer: 1.249 ± 0.293
1.124HisThr: 1.124 ± 0.269
2.123HisVal: 2.123 ± 0.579
0.749HisTrp: 0.749 ± 0.423
0.999HisTyr: 0.999 ± 0.34
0.0HisXaa: 0.0 ± 0.0
Ile
3.122IleAla: 3.122 ± 0.703
0.749IleCys: 0.749 ± 0.268
3.247IleAsp: 3.247 ± 0.625
2.123IleGlu: 2.123 ± 0.514
2.623IlePhe: 2.623 ± 0.77
3.622IleGly: 3.622 ± 0.748
0.874IleHis: 0.874 ± 0.351
2.623IleIle: 2.623 ± 0.518
2.123IleLys: 2.123 ± 0.614
5.245IleLeu: 5.245 ± 0.913
1.374IleMet: 1.374 ± 0.391
3.372IleAsn: 3.372 ± 0.458
3.872IlePro: 3.872 ± 0.909
2.872IleGln: 2.872 ± 0.607
4.621IleArg: 4.621 ± 0.904
4.746IleSer: 4.746 ± 0.74
3.622IleThr: 3.622 ± 1.149
3.622IleVal: 3.622 ± 0.778
0.5IleTrp: 0.5 ± 0.219
1.499IleTyr: 1.499 ± 0.434
0.0IleXaa: 0.0 ± 0.0
Lys
2.748LysAla: 2.748 ± 0.735
0.749LysCys: 0.749 ± 0.31
2.373LysAsp: 2.373 ± 0.502
2.498LysGlu: 2.498 ± 0.53
1.624LysPhe: 1.624 ± 0.593
3.497LysGly: 3.497 ± 0.637
1.624LysHis: 1.624 ± 0.447
3.497LysIle: 3.497 ± 0.894
3.622LysLys: 3.622 ± 1.207
3.997LysLeu: 3.997 ± 1.082
1.124LysMet: 1.124 ± 0.502
3.122LysAsn: 3.122 ± 0.784
1.998LysPro: 1.998 ± 0.497
1.624LysGln: 1.624 ± 0.389
4.746LysArg: 4.746 ± 0.836
2.872LysSer: 2.872 ± 0.683
3.747LysThr: 3.747 ± 0.57
1.624LysVal: 1.624 ± 0.439
0.5LysTrp: 0.5 ± 0.292
1.624LysTyr: 1.624 ± 0.389
0.0LysXaa: 0.0 ± 0.0
Leu
6.744LeuAla: 6.744 ± 0.756
2.248LeuCys: 2.248 ± 0.699
5.121LeuAsp: 5.121 ± 0.749
5.62LeuGlu: 5.62 ± 0.989
2.748LeuPhe: 2.748 ± 0.592
4.746LeuGly: 4.746 ± 1.039
2.997LeuHis: 2.997 ± 0.574
4.746LeuIle: 4.746 ± 0.556
6.12LeuLys: 6.12 ± 0.948
7.119LeuLeu: 7.119 ± 0.815
2.872LeuMet: 2.872 ± 0.667
5.745LeuAsn: 5.745 ± 1.146
5.745LeuPro: 5.745 ± 0.802
4.246LeuGln: 4.246 ± 0.687
5.245LeuArg: 5.245 ± 0.879
6.12LeuSer: 6.12 ± 1.205
6.869LeuThr: 6.869 ± 0.886
3.872LeuVal: 3.872 ± 0.564
0.874LeuTrp: 0.874 ± 0.248
3.747LeuTyr: 3.747 ± 0.79
0.0LeuXaa: 0.0 ± 0.0
Met
1.624MetAla: 1.624 ± 0.398
0.375MetCys: 0.375 ± 0.188
2.123MetAsp: 2.123 ± 0.634
1.998MetGlu: 1.998 ± 0.468
0.624MetPhe: 0.624 ± 0.266
1.748MetGly: 1.748 ± 0.465
0.749MetHis: 0.749 ± 0.383
1.249MetIle: 1.249 ± 0.365
0.749MetLys: 0.749 ± 0.339
2.373MetLeu: 2.373 ± 0.588
0.749MetMet: 0.749 ± 0.213
1.124MetAsn: 1.124 ± 0.355
1.374MetPro: 1.374 ± 0.433
0.5MetGln: 0.5 ± 0.257
1.374MetArg: 1.374 ± 0.495
1.873MetSer: 1.873 ± 0.477
1.124MetThr: 1.124 ± 0.449
1.124MetVal: 1.124 ± 0.368
0.624MetTrp: 0.624 ± 0.271
1.249MetTyr: 1.249 ± 0.334
0.0MetXaa: 0.0 ± 0.0
Asn
3.872AsnAla: 3.872 ± 0.755
0.874AsnCys: 0.874 ± 0.28
2.623AsnAsp: 2.623 ± 0.441
3.372AsnGlu: 3.372 ± 0.552
2.997AsnPhe: 2.997 ± 0.498
2.498AsnGly: 2.498 ± 0.619
0.749AsnHis: 0.749 ± 0.265
3.497AsnIle: 3.497 ± 0.658
2.498AsnLys: 2.498 ± 0.548
5.121AsnLeu: 5.121 ± 0.827
1.249AsnMet: 1.249 ± 0.4
2.248AsnAsn: 2.248 ± 0.481
3.622AsnPro: 3.622 ± 0.749
1.748AsnGln: 1.748 ± 0.389
2.997AsnArg: 2.997 ± 0.457
3.997AsnSer: 3.997 ± 0.728
2.872AsnThr: 2.872 ± 0.503
3.122AsnVal: 3.122 ± 0.611
1.374AsnTrp: 1.374 ± 0.346
2.872AsnTyr: 2.872 ± 0.639
0.0AsnXaa: 0.0 ± 0.0
Pro
3.372ProAla: 3.372 ± 0.47
0.5ProCys: 0.5 ± 0.21
2.997ProAsp: 2.997 ± 0.797
3.372ProGlu: 3.372 ± 0.903
2.748ProPhe: 2.748 ± 0.433
2.748ProGly: 2.748 ± 0.494
0.874ProHis: 0.874 ± 0.299
3.997ProIle: 3.997 ± 0.588
2.748ProLys: 2.748 ± 0.675
4.871ProLeu: 4.871 ± 1.338
1.124ProMet: 1.124 ± 0.384
2.748ProAsn: 2.748 ± 0.757
6.369ProPro: 6.369 ± 1.686
2.872ProGln: 2.872 ± 0.695
2.997ProArg: 2.997 ± 0.508
6.12ProSer: 6.12 ± 0.993
3.122ProThr: 3.122 ± 0.433
3.622ProVal: 3.622 ± 0.759
0.999ProTrp: 0.999 ± 0.58
2.373ProTyr: 2.373 ± 0.632
0.0ProXaa: 0.0 ± 0.0
Gln
1.873GlnAla: 1.873 ± 0.403
1.124GlnCys: 1.124 ± 0.368
1.499GlnAsp: 1.499 ± 0.275
2.498GlnGlu: 2.498 ± 0.672
1.374GlnPhe: 1.374 ± 0.478
1.624GlnGly: 1.624 ± 0.428
0.749GlnHis: 0.749 ± 0.26
1.748GlnIle: 1.748 ± 0.452
2.123GlnLys: 2.123 ± 0.562
3.872GlnLeu: 3.872 ± 0.578
0.749GlnMet: 0.749 ± 0.328
1.748GlnAsn: 1.748 ± 0.529
1.624GlnPro: 1.624 ± 0.366
1.124GlnGln: 1.124 ± 0.351
2.997GlnArg: 2.997 ± 0.502
3.872GlnSer: 3.872 ± 0.734
2.872GlnThr: 2.872 ± 0.383
2.123GlnVal: 2.123 ± 0.583
0.624GlnTrp: 0.624 ± 0.214
0.874GlnTyr: 0.874 ± 0.274
0.0GlnXaa: 0.0 ± 0.0
Arg
3.247ArgAla: 3.247 ± 0.564
0.999ArgCys: 0.999 ± 0.354
3.497ArgAsp: 3.497 ± 0.724
3.122ArgGlu: 3.122 ± 0.467
2.123ArgPhe: 2.123 ± 0.446
4.371ArgGly: 4.371 ± 0.681
1.624ArgHis: 1.624 ± 0.632
2.997ArgIle: 2.997 ± 0.572
3.997ArgLys: 3.997 ± 0.652
5.495ArgLeu: 5.495 ± 0.555
0.749ArgMet: 0.749 ± 0.31
4.621ArgAsn: 4.621 ± 0.875
1.998ArgPro: 1.998 ± 0.442
2.373ArgGln: 2.373 ± 0.484
7.119ArgArg: 7.119 ± 1.921
4.746ArgSer: 4.746 ± 0.679
2.748ArgThr: 2.748 ± 0.608
4.246ArgVal: 4.246 ± 0.982
1.249ArgTrp: 1.249 ± 0.344
2.748ArgTyr: 2.748 ± 0.569
0.0ArgXaa: 0.0 ± 0.0
Ser
4.996SerAla: 4.996 ± 0.864
1.499SerCys: 1.499 ± 0.503
2.872SerAsp: 2.872 ± 0.685
4.246SerGlu: 4.246 ± 0.709
5.37SerPhe: 5.37 ± 0.774
4.996SerGly: 4.996 ± 1.099
1.124SerHis: 1.124 ± 0.493
4.121SerIle: 4.121 ± 0.507
4.121SerLys: 4.121 ± 0.667
5.121SerLeu: 5.121 ± 0.806
1.374SerMet: 1.374 ± 0.47
3.372SerAsn: 3.372 ± 0.664
5.121SerPro: 5.121 ± 0.965
2.872SerGln: 2.872 ± 0.678
5.245SerArg: 5.245 ± 0.817
5.995SerSer: 5.995 ± 1.255
4.121SerThr: 4.121 ± 0.717
4.746SerVal: 4.746 ± 0.585
0.624SerTrp: 0.624 ± 0.303
2.997SerTyr: 2.997 ± 0.543
0.0SerXaa: 0.0 ± 0.0
Thr
2.872ThrAla: 2.872 ± 0.515
1.374ThrCys: 1.374 ± 0.36
3.247ThrAsp: 3.247 ± 0.897
3.872ThrGlu: 3.872 ± 0.539
4.746ThrPhe: 4.746 ± 0.903
2.872ThrGly: 2.872 ± 0.479
1.748ThrHis: 1.748 ± 0.264
3.497ThrIle: 3.497 ± 0.461
1.748ThrLys: 1.748 ± 0.352
7.369ThrLeu: 7.369 ± 1.065
0.874ThrMet: 0.874 ± 0.372
1.624ThrAsn: 1.624 ± 0.454
3.872ThrPro: 3.872 ± 0.633
1.998ThrGln: 1.998 ± 0.456
2.623ThrArg: 2.623 ± 0.565
3.747ThrSer: 3.747 ± 0.796
2.997ThrThr: 2.997 ± 0.618
3.622ThrVal: 3.622 ± 0.851
0.749ThrTrp: 0.749 ± 0.305
3.247ThrTyr: 3.247 ± 0.699
0.0ThrXaa: 0.0 ± 0.0
Val
2.748ValAla: 2.748 ± 0.47
0.624ValCys: 0.624 ± 0.272
3.747ValAsp: 3.747 ± 0.856
3.747ValGlu: 3.747 ± 0.745
2.373ValPhe: 2.373 ± 0.549
2.872ValGly: 2.872 ± 0.755
0.874ValHis: 0.874 ± 0.358
4.246ValIle: 4.246 ± 0.766
2.373ValLys: 2.373 ± 0.466
5.495ValLeu: 5.495 ± 0.655
1.249ValMet: 1.249 ± 0.334
3.122ValAsn: 3.122 ± 0.616
3.872ValPro: 3.872 ± 0.856
1.998ValGln: 1.998 ± 0.434
3.747ValArg: 3.747 ± 0.903
4.371ValSer: 4.371 ± 0.671
4.246ValThr: 4.246 ± 0.755
2.623ValVal: 2.623 ± 0.576
0.749ValTrp: 0.749 ± 0.246
2.623ValTyr: 2.623 ± 0.592
0.0ValXaa: 0.0 ± 0.0
Trp
0.375TrpAla: 0.375 ± 0.214
0.0TrpCys: 0.0 ± 0.0
1.249TrpAsp: 1.249 ± 0.373
0.749TrpGlu: 0.749 ± 0.321
0.25TrpPhe: 0.25 ± 0.166
1.249TrpGly: 1.249 ± 0.372
0.125TrpHis: 0.125 ± 0.142
0.375TrpIle: 0.375 ± 0.191
0.749TrpLys: 0.749 ± 0.355
1.124TrpLeu: 1.124 ± 0.339
0.25TrpMet: 0.25 ± 0.143
0.624TrpAsn: 0.624 ± 0.217
0.874TrpPro: 0.874 ± 0.246
1.124TrpGln: 1.124 ± 0.377
0.5TrpArg: 0.5 ± 0.297
1.374TrpSer: 1.374 ± 0.584
0.749TrpThr: 0.749 ± 0.355
0.624TrpVal: 0.624 ± 0.279
0.125TrpTrp: 0.125 ± 0.125
0.749TrpTyr: 0.749 ± 0.386
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.998TyrAla: 1.998 ± 0.467
0.874TyrCys: 0.874 ± 0.394
1.748TyrAsp: 1.748 ± 0.485
2.248TyrGlu: 2.248 ± 0.541
2.123TyrPhe: 2.123 ± 0.538
1.998TyrGly: 1.998 ± 0.332
1.998TyrHis: 1.998 ± 0.481
2.373TyrIle: 2.373 ± 0.455
0.874TyrLys: 0.874 ± 0.237
3.872TyrLeu: 3.872 ± 0.792
1.624TyrMet: 1.624 ± 0.381
1.748TyrAsn: 1.748 ± 0.625
1.873TyrPro: 1.873 ± 0.329
1.873TyrGln: 1.873 ± 0.555
1.998TyrArg: 1.998 ± 0.473
3.247TyrSer: 3.247 ± 0.883
2.997TyrThr: 2.997 ± 0.577
1.624TyrVal: 1.624 ± 0.517
0.5TyrTrp: 0.5 ± 0.212
1.374TyrTyr: 1.374 ± 0.474
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 21 proteins (8008 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski