Amino acid dipepetide frequency for Zootermopsis nevadensis (Dampwood termite)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.308AlaAla: 5.308 ± 0.047	1.27AlaCys: 1.27 ± 0.016	3.144AlaAsp: 3.144 ± 0.025	4.005AlaGlu: 4.005 ± 0.038	2.273AlaPhe: 2.273 ± 0.025	3.797AlaGly: 3.797 ± 0.039	1.449AlaHis: 1.449 ± 0.018	2.93AlaIle: 2.93 ± 0.025	3.077AlaLys: 3.077 ± 0.025	5.852AlaLeu: 5.852 ± 0.041	1.506AlaMet: 1.506 ± 0.018	2.245AlaAsn: 2.245 ± 0.019	2.772AlaPro: 2.772 ± 0.032	2.354AlaGln: 2.354 ± 0.027	3.189AlaArg: 3.189 ± 0.035	5.227AlaSer: 5.227 ± 0.039	3.752AlaThr: 3.752 ± 0.03	5.074AlaVal: 5.074 ± 0.035	0.684AlaTrp: 0.684 ± 0.011	1.601AlaTyr: 1.601 ± 0.02	0.003AlaXaa: 0.003 ± 0.001
Cys	1.122CysAla: 1.122 ± 0.016	0.599CysCys: 0.599 ± 0.014	1.288CysAsp: 1.288 ± 0.022	1.24CysGlu: 1.24 ± 0.018	0.853CysPhe: 0.853 ± 0.014	1.601CysGly: 1.601 ± 0.027	0.684CysHis: 0.684 ± 0.012	1.133CysIle: 1.133 ± 0.018	1.16CysLys: 1.16 ± 0.017	2.098CysLeu: 2.098 ± 0.027	0.518CysMet: 0.518 ± 0.023	1.045CysAsn: 1.045 ± 0.017	1.115CysPro: 1.115 ± 0.019	0.861CysGln: 0.861 ± 0.013	1.209CysArg: 1.209 ± 0.016	1.937CysSer: 1.937 ± 0.023	1.171CysThr: 1.171 ± 0.02	1.502CysVal: 1.502 ± 0.02	0.274CysTrp: 0.274 ± 0.007	0.627CysTyr: 0.627 ± 0.01	0.001CysXaa: 0.001 ± 0.0
Asp	2.956AspAla: 2.956 ± 0.024	1.099AspCys: 1.099 ± 0.019	3.539AspAsp: 3.539 ± 0.046	3.803AspGlu: 3.803 ± 0.038	2.156AspPhe: 2.156 ± 0.023	3.353AspGly: 3.353 ± 0.037	1.225AspHis: 1.225 ± 0.016	3.232AspIle: 3.232 ± 0.025	2.927AspLys: 2.927 ± 0.028	4.811AspLeu: 4.811 ± 0.033	1.359AspMet: 1.359 ± 0.017	2.171AspAsn: 2.171 ± 0.022	2.421AspPro: 2.421 ± 0.024	1.678AspGln: 1.678 ± 0.017	2.668AspArg: 2.668 ± 0.029	4.417AspSer: 4.417 ± 0.035	2.867AspThr: 2.867 ± 0.027	3.905AspVal: 3.905 ± 0.027	0.639AspTrp: 0.639 ± 0.011	1.583AspTyr: 1.583 ± 0.018	0.001AspXaa: 0.001 ± 0.0
Glu	3.989GluAla: 3.989 ± 0.029	1.264GluCys: 1.264 ± 0.021	4.205GluAsp: 4.205 ± 0.042	6.236GluGlu: 6.236 ± 0.081	2.157GluPhe: 2.157 ± 0.018	3.535GluGly: 3.535 ± 0.035	1.6GluHis: 1.6 ± 0.019	3.285GluIle: 3.285 ± 0.031	4.516GluLys: 4.516 ± 0.066	5.827GluLeu: 5.827 ± 0.044	1.687GluMet: 1.687 ± 0.02	3.241GluAsn: 3.241 ± 0.03	2.372GluPro: 2.372 ± 0.026	2.714GluGln: 2.714 ± 0.028	3.696GluArg: 3.696 ± 0.036	4.41GluSer: 4.41 ± 0.036	3.723GluThr: 3.723 ± 0.034	4.317GluVal: 4.317 ± 0.035	0.674GluTrp: 0.674 ± 0.012	1.757GluTyr: 1.757 ± 0.019	0.002GluXaa: 0.002 ± 0.001
Phe	2.012PheAla: 2.012 ± 0.02	0.918PheCys: 0.918 ± 0.014	1.821PheAsp: 1.821 ± 0.018	2.066PheGlu: 2.066 ± 0.02	1.53PhePhe: 1.53 ± 0.018	2.355PheGly: 2.355 ± 0.027	1.135PheHis: 1.135 ± 0.015	2.007PheIle: 2.007 ± 0.021	1.89PheLys: 1.89 ± 0.02	3.857PheLeu: 3.857 ± 0.031	0.882PheMet: 0.882 ± 0.014	1.546PheAsn: 1.546 ± 0.017	1.868PhePro: 1.868 ± 0.018	1.62PheGln: 1.62 ± 0.017	2.042PheArg: 2.042 ± 0.021	3.281PheSer: 3.281 ± 0.028	2.203PheThr: 2.203 ± 0.022	2.628PheVal: 2.628 ± 0.028	0.468PheTrp: 0.468 ± 0.01	1.255PheTyr: 1.255 ± 0.017	0.001PheXaa: 0.001 ± 0.0
Gly	3.399GlyAla: 3.399 ± 0.03	1.241GlyCys: 1.241 ± 0.019	3.193GlyAsp: 3.193 ± 0.03	3.571GlyGlu: 3.571 ± 0.043	2.315GlyPhe: 2.315 ± 0.024	4.871GlyGly: 4.871 ± 0.076	1.71GlyHis: 1.71 ± 0.025	3.149GlyIle: 3.149 ± 0.03	3.538GlyLys: 3.538 ± 0.034	4.992GlyLeu: 4.992 ± 0.046	1.369GlyMet: 1.369 ± 0.019	2.821GlyAsn: 2.821 ± 0.024	2.568GlyPro: 2.568 ± 0.05	2.239GlyGln: 2.239 ± 0.024	3.441GlyArg: 3.441 ± 0.037	5.503GlySer: 5.503 ± 0.062	3.534GlyThr: 3.534 ± 0.031	3.8GlyVal: 3.8 ± 0.03	0.684GlyTrp: 0.684 ± 0.016	1.908GlyTyr: 1.908 ± 0.024	0.002GlyXaa: 0.002 ± 0.001
His	1.412HisAla: 1.412 ± 0.016	0.705HisCys: 0.705 ± 0.013	1.213HisAsp: 1.213 ± 0.016	1.492HisGlu: 1.492 ± 0.015	1.149HisPhe: 1.149 ± 0.016	1.619HisGly: 1.619 ± 0.022	1.368HisHis: 1.368 ± 0.031	1.536HisIle: 1.536 ± 0.018	1.475HisLys: 1.475 ± 0.018	2.868HisLeu: 2.868 ± 0.027	0.713HisMet: 0.713 ± 0.01	1.24HisAsn: 1.24 ± 0.019	1.492HisPro: 1.492 ± 0.018	1.407HisGln: 1.407 ± 0.022	1.717HisArg: 1.717 ± 0.018	2.462HisSer: 2.462 ± 0.029	1.751HisThr: 1.751 ± 0.044	1.832HisVal: 1.832 ± 0.018	0.349HisTrp: 0.349 ± 0.008	0.912HisTyr: 0.912 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.043IleAla: 3.043 ± 0.026	1.211IleCys: 1.211 ± 0.019	2.353IleAsp: 2.353 ± 0.025	2.812IleGlu: 2.812 ± 0.023	1.987IlePhe: 1.987 ± 0.019	2.618IleGly: 2.618 ± 0.023	1.635IleHis: 1.635 ± 0.041	2.812IleIle: 2.812 ± 0.028	2.878IleLys: 2.878 ± 0.028	5.021IleLeu: 5.021 ± 0.042	1.187IleMet: 1.187 ± 0.015	2.209IleAsn: 2.209 ± 0.021	2.788IlePro: 2.788 ± 0.028	2.28IleGln: 2.28 ± 0.022	2.613IleArg: 2.613 ± 0.023	4.155IleSer: 4.155 ± 0.027	2.998IleThr: 2.998 ± 0.025	3.255IleVal: 3.255 ± 0.024	0.54IleTrp: 0.54 ± 0.011	1.479IleTyr: 1.479 ± 0.023	0.001IleXaa: 0.001 ± 0.0
Lys	3.25LysAla: 3.25 ± 0.033	1.258LysCys: 1.258 ± 0.018	3.088LysAsp: 3.088 ± 0.028	4.547LysGlu: 4.547 ± 0.067	2.057LysPhe: 2.057 ± 0.019	2.896LysGly: 2.896 ± 0.037	1.617LysHis: 1.617 ± 0.018	2.983LysIle: 2.983 ± 0.027	4.706LysLys: 4.706 ± 0.064	5.497LysLeu: 5.497 ± 0.04	1.54LysMet: 1.54 ± 0.016	2.609LysAsn: 2.609 ± 0.026	2.724LysPro: 2.724 ± 0.035	2.669LysGln: 2.669 ± 0.028	3.514LysArg: 3.514 ± 0.028	4.246LysSer: 4.246 ± 0.042	3.31LysThr: 3.31 ± 0.028	3.615LysVal: 3.615 ± 0.031	0.644LysTrp: 0.644 ± 0.011	1.836LysTyr: 1.836 ± 0.02	0.001LysXaa: 0.001 ± 0.0
Leu	6.056LeuAla: 6.056 ± 0.043	2.114LeuCys: 2.114 ± 0.023	4.712LeuAsp: 4.712 ± 0.031	6.074LeuGlu: 6.074 ± 0.05	3.362LeuPhe: 3.362 ± 0.033	4.966LeuGly: 4.966 ± 0.038	2.911LeuHis: 2.911 ± 0.028	4.14LeuIle: 4.14 ± 0.031	5.788LeuLys: 5.788 ± 0.039	9.467LeuLeu: 9.467 ± 0.069	2.098LeuMet: 2.098 ± 0.021	3.899LeuAsn: 3.899 ± 0.029	5.082LeuPro: 5.082 ± 0.038	5.096LeuGln: 5.096 ± 0.04	5.381LeuArg: 5.381 ± 0.034	7.521LeuSer: 7.521 ± 0.045	5.102LeuThr: 5.102 ± 0.04	5.875LeuVal: 5.875 ± 0.042	1.052LeuTrp: 1.052 ± 0.017	2.723LeuTyr: 2.723 ± 0.026	0.003LeuXaa: 0.003 ± 0.001
Met	1.806MetAla: 1.806 ± 0.019	0.524MetCys: 0.524 ± 0.011	1.283MetAsp: 1.283 ± 0.016	1.656MetGlu: 1.656 ± 0.019	0.929MetPhe: 0.929 ± 0.013	1.262MetGly: 1.262 ± 0.017	0.533MetHis: 0.533 ± 0.01	0.984MetIle: 0.984 ± 0.015	1.649MetLys: 1.649 ± 0.022	2.174MetLeu: 2.174 ± 0.021	0.646MetMet: 0.646 ± 0.01	1.044MetAsn: 1.044 ± 0.012	1.063MetPro: 1.063 ± 0.015	0.999MetGln: 0.999 ± 0.014	1.174MetArg: 1.174 ± 0.016	1.881MetSer: 1.881 ± 0.019	1.322MetThr: 1.322 ± 0.018	1.486MetVal: 1.486 ± 0.016	0.309MetTrp: 0.309 ± 0.008	0.77MetTyr: 0.77 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.375AsnAla: 2.375 ± 0.021	0.971AsnCys: 0.971 ± 0.015	1.976AsnAsp: 1.976 ± 0.018	2.6AsnGlu: 2.6 ± 0.029	1.758AsnPhe: 1.758 ± 0.018	2.668AsnGly: 2.668 ± 0.031	1.152AsnHis: 1.152 ± 0.017	2.807AsnIle: 2.807 ± 0.023	2.749AsnLys: 2.749 ± 0.024	4.031AsnLeu: 4.031 ± 0.031	1.127AsnMet: 1.127 ± 0.015	2.403AsnAsn: 2.403 ± 0.03	2.127AsnPro: 2.127 ± 0.025	1.644AsnGln: 1.644 ± 0.018	2.204AsnArg: 2.204 ± 0.024	3.836AsnSer: 3.836 ± 0.035	2.564AsnThr: 2.564 ± 0.027	3.067AsnVal: 3.067 ± 0.023	0.491AsnTrp: 0.491 ± 0.01	1.417AsnTyr: 1.417 ± 0.017	0.001AsnXaa: 0.001 ± 0.001
Pro	3.172ProAla: 3.172 ± 0.031	0.952ProCys: 0.952 ± 0.019	2.715ProAsp: 2.715 ± 0.025	3.256ProGlu: 3.256 ± 0.032	1.788ProPhe: 1.788 ± 0.022	3.195ProGly: 3.195 ± 0.065	1.468ProHis: 1.468 ± 0.016	2.087ProIle: 2.087 ± 0.021	2.384ProLys: 2.384 ± 0.027	4.346ProLeu: 4.346 ± 0.032	0.915ProMet: 0.915 ± 0.015	1.967ProAsn: 1.967 ± 0.019	4.295ProPro: 4.295 ± 0.086	2.262ProGln: 2.262 ± 0.028	2.671ProArg: 2.671 ± 0.033	4.726ProSer: 4.726 ± 0.048	2.963ProThr: 2.963 ± 0.034	3.818ProVal: 3.818 ± 0.04	0.526ProTrp: 0.526 ± 0.01	1.592ProTyr: 1.592 ± 0.022	0.002ProXaa: 0.002 ± 0.001
Gln	2.563GlnAla: 2.563 ± 0.025	0.919GlnCys: 0.919 ± 0.018	2.111GlnAsp: 2.111 ± 0.023	3.04GlnGlu: 3.04 ± 0.03	1.474GlnPhe: 1.474 ± 0.015	2.282GlnGly: 2.282 ± 0.029	1.497GlnHis: 1.497 ± 0.021	2.007GlnIle: 2.007 ± 0.018	2.599GlnLys: 2.599 ± 0.029	4.272GlnLeu: 4.272 ± 0.043	1.076GlnMet: 1.076 ± 0.016	2.072GlnAsn: 2.072 ± 0.026	2.118GlnPro: 2.118 ± 0.033	3.365GlnGln: 3.365 ± 0.082	2.64GlnArg: 2.64 ± 0.026	3.062GlnSer: 3.062 ± 0.029	2.341GlnThr: 2.341 ± 0.026	2.704GlnVal: 2.704 ± 0.025	0.495GlnTrp: 0.495 ± 0.01	1.265GlnTyr: 1.265 ± 0.014	0.001GlnXaa: 0.001 ± 0.0
Arg	3.004ArgAla: 3.004 ± 0.022	1.177ArgCys: 1.177 ± 0.019	2.924ArgAsp: 2.924 ± 0.028	3.514ArgGlu: 3.514 ± 0.033	2.026ArgPhe: 2.026 ± 0.019	3.209ArgGly: 3.209 ± 0.044	1.765ArgHis: 1.765 ± 0.024	2.754ArgIle: 2.754 ± 0.022	3.808ArgLys: 3.808 ± 0.033	5.191ArgLeu: 5.191 ± 0.041	1.294ArgMet: 1.294 ± 0.016	2.693ArgAsn: 2.693 ± 0.027	2.624ArgPro: 2.624 ± 0.028	2.488ArgGln: 2.488 ± 0.023	4.311ArgArg: 4.311 ± 0.041	4.388ArgSer: 4.388 ± 0.039	2.936ArgThr: 2.936 ± 0.026	3.213ArgVal: 3.213 ± 0.026	0.697ArgTrp: 0.697 ± 0.01	1.643ArgTyr: 1.643 ± 0.018	0.003ArgXaa: 0.003 ± 0.001
Ser	5.203SerAla: 5.203 ± 0.041	1.796SerCys: 1.796 ± 0.025	4.602SerAsp: 4.602 ± 0.039	5.111SerGlu: 5.111 ± 0.043	2.924SerPhe: 2.924 ± 0.027	5.677SerGly: 5.677 ± 0.051	2.391SerHis: 2.391 ± 0.025	3.592SerIle: 3.592 ± 0.03	4.295SerLys: 4.295 ± 0.039	7.524SerLeu: 7.524 ± 0.048	1.668SerMet: 1.668 ± 0.018	3.583SerAsn: 3.583 ± 0.031	4.872SerPro: 4.872 ± 0.049	3.477SerGln: 3.477 ± 0.033	4.466SerArg: 4.466 ± 0.041	9.673SerSer: 9.673 ± 0.088	4.983SerThr: 4.983 ± 0.057	5.968SerVal: 5.968 ± 0.04	0.89SerTrp: 0.89 ± 0.015	2.296SerTyr: 2.296 ± 0.022	0.003SerXaa: 0.003 ± 0.001
Thr	4.086ThrAla: 4.086 ± 0.035	1.28ThrCys: 1.28 ± 0.02	2.944ThrAsp: 2.944 ± 0.025	3.694ThrGlu: 3.694 ± 0.034	2.187ThrPhe: 2.187 ± 0.02	3.676ThrGly: 3.676 ± 0.034	1.5ThrHis: 1.5 ± 0.021	2.646ThrIle: 2.646 ± 0.023	3.02ThrLys: 3.02 ± 0.025	5.263ThrLeu: 5.263 ± 0.038	1.223ThrMet: 1.223 ± 0.015	2.375ThrAsn: 2.375 ± 0.021	3.311ThrPro: 3.311 ± 0.044	2.238ThrGln: 2.238 ± 0.035	2.781ThrArg: 2.781 ± 0.023	5.453ThrSer: 5.453 ± 0.052	3.785ThrThr: 3.785 ± 0.052	4.292ThrVal: 4.292 ± 0.037	0.689ThrTrp: 0.689 ± 0.012	1.697ThrTyr: 1.697 ± 0.039	0.001ThrXaa: 0.001 ± 0.001
Val	4.568ValAla: 4.568 ± 0.031	1.772ValCys: 1.772 ± 0.038	3.498ValAsp: 3.498 ± 0.029	4.104ValGlu: 4.104 ± 0.032	2.623ValPhe: 2.623 ± 0.026	3.751ValGly: 3.751 ± 0.031	1.823ValHis: 1.823 ± 0.022	3.529ValIle: 3.529 ± 0.024	3.749ValLys: 3.749 ± 0.029	6.413ValLeu: 6.413 ± 0.043	1.672ValMet: 1.672 ± 0.017	2.833ValAsn: 2.833 ± 0.027	3.671ValPro: 3.671 ± 0.033	2.774ValGln: 2.774 ± 0.025	3.49ValArg: 3.49 ± 0.031	5.539ValSer: 5.539 ± 0.039	4.538ValThr: 4.538 ± 0.032	4.768ValVal: 4.768 ± 0.051	0.796ValTrp: 0.796 ± 0.014	1.91ValTyr: 1.91 ± 0.024	0.003ValXaa: 0.003 ± 0.001
Trp	0.598TrpAla: 0.598 ± 0.012	0.253TrpCys: 0.253 ± 0.007	0.668TrpAsp: 0.668 ± 0.018	0.668TrpGlu: 0.668 ± 0.011	0.479TrpPhe: 0.479 ± 0.01	0.64TrpGly: 0.64 ± 0.013	0.298TrpHis: 0.298 ± 0.007	0.588TrpIle: 0.588 ± 0.011	0.779TrpLys: 0.779 ± 0.017	1.152TrpLeu: 1.152 ± 0.018	0.299TrpMet: 0.299 ± 0.007	0.605TrpAsn: 0.605 ± 0.011	0.453TrpPro: 0.453 ± 0.009	0.504TrpGln: 0.504 ± 0.01	0.722TrpArg: 0.722 ± 0.011	0.869TrpSer: 0.869 ± 0.015	0.665TrpThr: 0.665 ± 0.012	0.68TrpVal: 0.68 ± 0.013	0.197TrpTrp: 0.197 ± 0.007	0.36TrpTyr: 0.36 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.587TyrAla: 1.587 ± 0.018	0.717TyrCys: 0.717 ± 0.014	1.529TyrAsp: 1.529 ± 0.021	1.714TyrGlu: 1.714 ± 0.019	1.358TyrPhe: 1.358 ± 0.018	1.877TyrGly: 1.877 ± 0.033	0.95TyrHis: 0.95 ± 0.014	1.674TyrIle: 1.674 ± 0.042	1.618TyrLys: 1.618 ± 0.018	2.764TyrLeu: 2.764 ± 0.024	0.712TyrMet: 0.712 ± 0.011	1.366TyrAsn: 1.366 ± 0.016	1.364TyrPro: 1.364 ± 0.021	1.234TyrGln: 1.234 ± 0.015	1.729TyrArg: 1.729 ± 0.018	2.408TyrSer: 2.408 ± 0.021	1.63TyrThr: 1.63 ± 0.018	2.02TyrVal: 2.02 ± 0.032	0.379TyrTrp: 0.379 ± 0.011	1.076TyrTyr: 1.076 ± 0.016	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.002XaaGlu: 0.002 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.003XaaLeu: 0.003 ± 0.001	0.002XaaMet: 0.002 ± 0.001	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.002XaaGln: 0.002 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.002XaaSer: 0.002 ± 0.001	0.001XaaThr: 0.001 ± 0.001	0.003XaaVal: 0.003 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.278XaaXaa: 0.278 ± 0.023

Statistics based on 14539 proteins (6045344 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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