Amino acid dipepetide frequency for Epichloe festucae virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.844AlaAla: 18.844 ± 0.521
1.256AlaCys: 1.256 ± 0.035
5.025AlaAsp: 5.025 ± 0.139
5.025AlaGlu: 5.025 ± 1.046
3.769AlaPhe: 3.769 ± 0.802
9.422AlaGly: 9.422 ± 0.714
1.884AlaHis: 1.884 ± 0.505
3.141AlaIle: 3.141 ± 0.54
2.513AlaLys: 2.513 ± 0.069
10.678AlaLeu: 10.678 ± 0.749
3.769AlaMet: 3.769 ± 0.607
5.025AlaAsn: 5.025 ± 0.768
10.678AlaPro: 10.678 ± 3.468
3.769AlaGln: 3.769 ± 1.011
9.422AlaArg: 9.422 ± 0.193
10.678AlaSer: 10.678 ± 0.158
10.678AlaThr: 10.678 ± 0.158
6.91AlaVal: 6.91 ± 0.644
2.513AlaTrp: 2.513 ± 0.069
3.141AlaTyr: 3.141 ± 1.273
0.0AlaXaa: 0.0 ± 0.0
Cys
1.884CysAla: 1.884 ± 1.412
0.0CysCys: 0.0 ± 0.0
1.884CysAsp: 1.884 ± 0.401
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.884CysGly: 1.884 ± 0.401
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.628CysLeu: 0.628 ± 0.436
0.0CysMet: 0.0 ± 0.0
0.628CysAsn: 0.628 ± 0.436
0.0CysPro: 0.0 ± 0.0
0.628CysGln: 0.628 ± 0.436
0.0CysArg: 0.0 ± 0.0
1.884CysSer: 1.884 ± 0.505
0.628CysThr: 0.628 ± 0.436
1.256CysVal: 1.256 ± 0.941
0.0CysTrp: 0.0 ± 0.0
1.884CysTyr: 1.884 ± 0.401
0.0CysXaa: 0.0 ± 0.0
Asp
3.769AspAla: 3.769 ± 0.104
1.256AspCys: 1.256 ± 0.035
2.513AspAsp: 2.513 ± 0.069
1.256AspGlu: 1.256 ± 0.035
1.884AspPhe: 1.884 ± 0.505
2.513AspGly: 2.513 ± 0.069
2.513AspHis: 2.513 ± 0.069
1.256AspIle: 1.256 ± 0.035
1.256AspLys: 1.256 ± 0.872
5.653AspLeu: 5.653 ± 0.61
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
5.025AspPro: 5.025 ± 1.046
1.884AspGln: 1.884 ± 0.505
1.884AspArg: 1.884 ± 0.401
3.141AspSer: 3.141 ± 0.366
2.513AspThr: 2.513 ± 0.837
6.281AspVal: 6.281 ± 1.08
1.256AspTrp: 1.256 ± 0.941
2.513AspTyr: 2.513 ± 1.744
0.0AspXaa: 0.0 ± 0.0
Glu
5.025GluAla: 5.025 ± 1.674
0.0GluCys: 0.0 ± 0.0
1.256GluAsp: 1.256 ± 0.872
3.141GluGlu: 3.141 ± 0.366
1.884GluPhe: 1.884 ± 0.401
3.769GluGly: 3.769 ± 1.917
2.513GluHis: 2.513 ± 0.837
0.628GluIle: 0.628 ± 0.471
1.256GluLys: 1.256 ± 0.941
3.141GluLeu: 3.141 ± 2.18
0.0GluMet: 0.0 ± 0.0
1.884GluAsn: 1.884 ± 0.505
2.513GluPro: 2.513 ± 0.976
1.256GluGln: 1.256 ± 0.035
2.513GluArg: 2.513 ± 0.069
4.397GluSer: 4.397 ± 0.575
2.513GluThr: 2.513 ± 0.069
3.769GluVal: 3.769 ± 0.802
0.628GluTrp: 0.628 ± 0.436
3.141GluTyr: 3.141 ± 1.273
0.0GluXaa: 0.0 ± 0.0
Phe
4.397PheAla: 4.397 ± 2.388
0.628PheCys: 0.628 ± 0.436
1.256PheAsp: 1.256 ± 0.035
2.513PheGlu: 2.513 ± 0.069
0.628PhePhe: 0.628 ± 0.436
2.513PheGly: 2.513 ± 0.976
0.0PheHis: 0.0 ± 0.0
1.256PheIle: 1.256 ± 0.941
0.628PheLys: 0.628 ± 0.471
1.884PheLeu: 1.884 ± 0.401
0.0PheMet: 0.0 ± 0.0
1.884PheAsn: 1.884 ± 1.308
0.628PhePro: 0.628 ± 0.436
0.628PheGln: 0.628 ± 0.471
1.884PheArg: 1.884 ± 1.412
0.0PheSer: 0.0 ± 0.0
0.0PheThr: 0.0 ± 0.0
1.256PheVal: 1.256 ± 0.035
1.256PheTrp: 1.256 ± 0.035
1.256PheTyr: 1.256 ± 0.035
0.0PheXaa: 0.0 ± 0.0
Gly
10.05GlyAla: 10.05 ± 2.091
1.884GlyCys: 1.884 ± 0.505
3.769GlyAsp: 3.769 ± 1.917
4.397GlyGlu: 4.397 ± 1.238
1.884GlyPhe: 1.884 ± 0.505
6.281GlyGly: 6.281 ± 1.08
2.513GlyHis: 2.513 ± 0.069
3.769GlyIle: 3.769 ± 1.917
6.281GlyLys: 6.281 ± 2.546
6.91GlyLeu: 6.91 ± 1.551
1.256GlyMet: 1.256 ± 0.035
4.397GlyAsn: 4.397 ± 1.238
5.025GlyPro: 5.025 ± 1.952
1.256GlyGln: 1.256 ± 0.941
5.025GlyArg: 5.025 ± 1.046
5.653GlySer: 5.653 ± 1.204
4.397GlyThr: 4.397 ± 0.575
4.397GlyVal: 4.397 ± 0.332
0.628GlyTrp: 0.628 ± 0.436
3.769GlyTyr: 3.769 ± 0.802
0.0GlyXaa: 0.0 ± 0.0
His
0.628HisAla: 0.628 ± 0.436
0.628HisCys: 0.628 ± 0.471
0.628HisAsp: 0.628 ± 0.471
1.256HisGlu: 1.256 ± 0.941
0.0HisPhe: 0.0 ± 0.0
1.884HisGly: 1.884 ± 1.308
1.256HisHis: 1.256 ± 0.872
0.0HisIle: 0.0 ± 0.0
1.884HisLys: 1.884 ± 0.505
3.141HisLeu: 3.141 ± 0.54
1.256HisMet: 1.256 ± 0.035
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.628HisGln: 0.628 ± 0.436
2.513HisArg: 2.513 ± 0.976
0.0HisSer: 0.0 ± 0.0
3.769HisThr: 3.769 ± 0.104
1.884HisVal: 1.884 ± 0.401
0.628HisTrp: 0.628 ± 0.436
3.141HisTyr: 3.141 ± 1.447
0.0HisXaa: 0.0 ± 0.0
Ile
6.91IleAla: 6.91 ± 2.457
0.0IleCys: 0.0 ± 0.0
0.628IleAsp: 0.628 ± 0.471
0.628IleGlu: 0.628 ± 0.436
1.256IlePhe: 1.256 ± 0.035
1.256IleGly: 1.256 ± 0.035
0.628IleHis: 0.628 ± 0.471
0.0IleIle: 0.0 ± 0.0
0.628IleLys: 0.628 ± 0.471
1.256IleLeu: 1.256 ± 0.035
0.0IleMet: 0.0 ± 0.0
1.884IleAsn: 1.884 ± 1.412
2.513IlePro: 2.513 ± 0.976
1.884IleGln: 1.884 ± 0.401
0.628IleArg: 0.628 ± 0.471
3.141IleSer: 3.141 ± 0.54
1.884IleThr: 1.884 ± 1.308
1.256IleVal: 1.256 ± 0.872
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.769LysAla: 3.769 ± 1.709
0.0LysCys: 0.0 ± 0.0
0.628LysAsp: 0.628 ± 0.471
0.628LysGlu: 0.628 ± 0.436
0.628LysPhe: 0.628 ± 0.471
1.884LysGly: 1.884 ± 0.401
0.628LysHis: 0.628 ± 0.471
0.628LysIle: 0.628 ± 0.471
0.0LysLys: 0.0 ± 0.0
2.513LysLeu: 2.513 ± 0.837
1.256LysMet: 1.256 ± 0.941
0.0LysAsn: 0.0 ± 0.0
1.884LysPro: 1.884 ± 0.401
1.884LysGln: 1.884 ± 0.401
1.256LysArg: 1.256 ± 0.872
0.628LysSer: 0.628 ± 0.436
3.141LysThr: 3.141 ± 0.366
1.884LysVal: 1.884 ± 0.401
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
15.704LeuAla: 15.704 ± 1.832
1.884LeuCys: 1.884 ± 1.412
4.397LeuAsp: 4.397 ± 1.238
5.653LeuGlu: 5.653 ± 3.017
2.513LeuPhe: 2.513 ± 0.976
9.422LeuGly: 9.422 ± 1.099
1.256LeuHis: 1.256 ± 0.035
0.628LeuIle: 0.628 ± 0.471
3.141LeuLys: 3.141 ± 0.366
11.935LeuLeu: 11.935 ± 4.656
2.513LeuMet: 2.513 ± 1.744
3.141LeuAsn: 3.141 ± 1.273
7.538LeuPro: 7.538 ± 0.698
2.513LeuGln: 2.513 ± 0.069
8.166LeuArg: 8.166 ± 0.679
5.653LeuSer: 5.653 ± 0.297
3.769LeuThr: 3.769 ± 1.709
5.025LeuVal: 5.025 ± 0.139
0.628LeuTrp: 0.628 ± 0.471
0.628LeuTyr: 0.628 ± 0.436
0.0LeuXaa: 0.0 ± 0.0
Met
2.513MetAla: 2.513 ± 1.744
0.0MetCys: 0.0 ± 0.0
0.628MetAsp: 0.628 ± 0.471
1.256MetGlu: 1.256 ± 0.941
0.0MetPhe: 0.0 ± 0.0
1.884MetGly: 1.884 ± 0.401
0.0MetHis: 0.0 ± 0.0
1.256MetIle: 1.256 ± 0.035
0.0MetLys: 0.0 ± 0.0
0.628MetLeu: 0.628 ± 0.436
0.628MetMet: 0.628 ± 0.471
0.628MetAsn: 0.628 ± 0.436
1.256MetPro: 1.256 ± 0.941
0.628MetGln: 0.628 ± 0.436
3.141MetArg: 3.141 ± 0.366
1.884MetSer: 1.884 ± 0.401
0.628MetThr: 0.628 ± 0.471
0.628MetVal: 0.628 ± 0.436
0.0MetTrp: 0.0 ± 0.0
1.256MetTyr: 1.256 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
5.025AsnAla: 5.025 ± 0.768
0.0AsnCys: 0.0 ± 0.0
1.256AsnAsp: 1.256 ± 0.872
0.628AsnGlu: 0.628 ± 0.471
1.884AsnPhe: 1.884 ± 1.412
2.513AsnGly: 2.513 ± 0.837
0.0AsnHis: 0.0 ± 0.0
0.628AsnIle: 0.628 ± 0.471
0.628AsnLys: 0.628 ± 0.436
1.256AsnLeu: 1.256 ± 0.872
2.513AsnMet: 2.513 ± 0.837
0.628AsnAsn: 0.628 ± 0.471
4.397AsnPro: 4.397 ± 2.145
0.0AsnGln: 0.0 ± 0.0
1.884AsnArg: 1.884 ± 0.505
1.884AsnSer: 1.884 ± 0.401
1.256AsnThr: 1.256 ± 0.035
0.628AsnVal: 0.628 ± 0.436
1.256AsnTrp: 1.256 ± 0.872
1.884AsnTyr: 1.884 ± 0.505
0.0AsnXaa: 0.0 ± 0.0
Pro
6.281ProAla: 6.281 ± 3.8
0.0ProCys: 0.0 ± 0.0
4.397ProAsp: 4.397 ± 0.332
2.513ProGlu: 2.513 ± 0.976
1.884ProPhe: 1.884 ± 1.308
6.281ProGly: 6.281 ± 1.08
1.256ProHis: 1.256 ± 0.872
1.256ProIle: 1.256 ± 0.035
0.0ProLys: 0.0 ± 0.0
8.794ProLeu: 8.794 ± 1.15
0.628ProMet: 0.628 ± 0.471
1.256ProAsn: 1.256 ± 0.035
9.422ProPro: 9.422 ± 4.34
3.141ProGln: 3.141 ± 0.54
5.025ProArg: 5.025 ± 0.139
4.397ProSer: 4.397 ± 0.575
8.166ProThr: 8.166 ± 4.305
4.397ProVal: 4.397 ± 0.575
0.628ProTrp: 0.628 ± 0.436
1.256ProTyr: 1.256 ± 0.941
0.0ProXaa: 0.0 ± 0.0
Gln
4.397GlnAla: 4.397 ± 1.481
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.628GlnGlu: 0.628 ± 0.471
1.256GlnPhe: 1.256 ± 0.941
3.769GlnGly: 3.769 ± 1.917
0.628GlnHis: 0.628 ± 0.471
1.256GlnIle: 1.256 ± 0.872
0.0GlnLys: 0.0 ± 0.0
1.884GlnLeu: 1.884 ± 0.505
0.628GlnMet: 0.628 ± 0.436
0.628GlnAsn: 0.628 ± 0.471
0.628GlnPro: 0.628 ± 0.471
0.0GlnGln: 0.0 ± 0.0
2.513GlnArg: 2.513 ± 0.837
2.513GlnSer: 2.513 ± 0.976
1.884GlnThr: 1.884 ± 0.505
1.884GlnVal: 1.884 ± 0.401
1.256GlnTrp: 1.256 ± 0.035
2.513GlnTyr: 2.513 ± 0.837
0.0GlnXaa: 0.0 ± 0.0
Arg
8.794ArgAla: 8.794 ± 0.243
1.256ArgCys: 1.256 ± 0.872
4.397ArgAsp: 4.397 ± 1.238
1.884ArgGlu: 1.884 ± 0.401
0.628ArgPhe: 0.628 ± 0.471
5.653ArgGly: 5.653 ± 1.516
5.653ArgHis: 5.653 ± 1.516
2.513ArgIle: 2.513 ± 0.837
1.884ArgLys: 1.884 ± 1.308
5.025ArgLeu: 5.025 ± 0.768
0.628ArgMet: 0.628 ± 0.436
0.628ArgAsn: 0.628 ± 0.436
2.513ArgPro: 2.513 ± 0.837
1.884ArgGln: 1.884 ± 1.412
5.653ArgArg: 5.653 ± 2.11
5.025ArgSer: 5.025 ± 1.046
5.025ArgThr: 5.025 ± 0.139
8.794ArgVal: 8.794 ± 1.57
1.256ArgTrp: 1.256 ± 0.872
1.256ArgTyr: 1.256 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
9.422SerAla: 9.422 ± 1.099
1.256SerCys: 1.256 ± 0.872
3.769SerAsp: 3.769 ± 1.917
3.141SerGlu: 3.141 ± 0.366
0.628SerPhe: 0.628 ± 0.436
4.397SerGly: 4.397 ± 0.575
3.141SerHis: 3.141 ± 0.54
3.769SerIle: 3.769 ± 0.104
1.884SerLys: 1.884 ± 0.401
8.794SerLeu: 8.794 ± 1.57
0.0SerMet: 0.0 ± 0.0
2.513SerAsn: 2.513 ± 0.976
5.653SerPro: 5.653 ± 2.423
1.256SerGln: 1.256 ± 0.941
3.141SerArg: 3.141 ± 1.273
5.653SerSer: 5.653 ± 0.61
5.653SerThr: 5.653 ± 0.61
8.166SerVal: 8.166 ± 1.134
1.256SerTrp: 1.256 ± 0.872
2.513SerTyr: 2.513 ± 0.837
0.0SerXaa: 0.0 ± 0.0
Thr
7.538ThrAla: 7.538 ± 2.022
0.628ThrCys: 0.628 ± 0.471
3.141ThrAsp: 3.141 ± 1.447
3.769ThrGlu: 3.769 ± 1.709
1.256ThrPhe: 1.256 ± 0.035
6.91ThrGly: 6.91 ± 1.551
0.628ThrHis: 0.628 ± 0.471
1.884ThrIle: 1.884 ± 0.505
1.256ThrLys: 1.256 ± 0.035
7.538ThrLeu: 7.538 ± 3.418
1.884ThrMet: 1.884 ± 1.412
1.884ThrAsn: 1.884 ± 0.401
3.769ThrPro: 3.769 ± 1.917
3.769ThrGln: 3.769 ± 1.917
3.769ThrArg: 3.769 ± 1.709
4.397ThrSer: 4.397 ± 0.575
3.141ThrThr: 3.141 ± 0.54
6.91ThrVal: 6.91 ± 1.169
0.0ThrTrp: 0.0 ± 0.0
1.256ThrTyr: 1.256 ± 0.872
0.0ThrXaa: 0.0 ± 0.0
Val
9.422ValAla: 9.422 ± 0.193
1.884ValCys: 1.884 ± 0.401
2.513ValAsp: 2.513 ± 0.976
4.397ValGlu: 4.397 ± 0.332
1.884ValPhe: 1.884 ± 1.412
6.281ValGly: 6.281 ± 0.174
0.0ValHis: 0.0 ± 0.0
1.256ValIle: 1.256 ± 0.035
0.0ValLys: 0.0 ± 0.0
9.422ValLeu: 9.422 ± 2.006
0.628ValMet: 0.628 ± 0.308
2.513ValAsn: 2.513 ± 1.744
4.397ValPro: 4.397 ± 2.388
1.256ValGln: 1.256 ± 0.872
6.281ValArg: 6.281 ± 1.639
11.935ValSer: 11.935 ± 1.03
3.769ValThr: 3.769 ± 1.011
7.538ValVal: 7.538 ± 0.208
0.0ValTrp: 0.0 ± 0.0
3.141ValTyr: 3.141 ± 2.18
0.0ValXaa: 0.0 ± 0.0
Trp
1.256TrpAla: 1.256 ± 0.872
0.628TrpCys: 0.628 ± 0.436
1.884TrpAsp: 1.884 ± 0.401
1.256TrpGlu: 1.256 ± 0.035
0.0TrpPhe: 0.0 ± 0.0
1.256TrpGly: 1.256 ± 0.872
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.628TrpLeu: 0.628 ± 0.436
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.513TrpArg: 2.513 ± 0.837
0.628TrpSer: 0.628 ± 0.436
0.628TrpThr: 0.628 ± 0.471
2.513TrpVal: 2.513 ± 0.976
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.141TyrAla: 3.141 ± 0.366
0.0TyrCys: 0.0 ± 0.0
4.397TyrAsp: 4.397 ± 2.145
1.256TyrGlu: 1.256 ± 0.035
0.628TyrPhe: 0.628 ± 0.471
3.769TyrGly: 3.769 ± 0.104
0.628TyrHis: 0.628 ± 0.436
1.256TyrIle: 1.256 ± 0.035
0.0TyrLys: 0.0 ± 0.0
4.397TyrLeu: 4.397 ± 1.238
0.628TyrMet: 0.628 ± 0.436
0.628TyrAsn: 0.628 ± 0.436
3.141TyrPro: 3.141 ± 0.366
0.0TyrGln: 0.0 ± 0.0
3.141TyrArg: 3.141 ± 0.366
2.513TyrSer: 2.513 ± 0.837
1.884TyrThr: 1.884 ± 0.401
3.141TyrVal: 3.141 ± 1.273
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1593 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski