Amino acid dipepetide frequency for Sulfuritortus calidifontis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.09AlaAla: 17.09 ± 0.233	1.288AlaCys: 1.288 ± 0.042	6.292AlaAsp: 6.292 ± 0.109	8.891AlaGlu: 8.891 ± 0.132	3.797AlaPhe: 3.797 ± 0.072	10.878AlaGly: 10.878 ± 0.155	2.484AlaHis: 2.484 ± 0.071	5.732AlaIle: 5.732 ± 0.096	4.825AlaLys: 4.825 ± 0.115	13.784AlaLeu: 13.784 ± 0.184	3.466AlaMet: 3.466 ± 0.072	2.905AlaAsn: 2.905 ± 0.078	5.032AlaPro: 5.032 ± 0.09	4.9AlaGln: 4.9 ± 0.094	8.978AlaArg: 8.978 ± 0.142	5.401AlaSer: 5.401 ± 0.079	4.898AlaThr: 4.898 ± 0.075	8.323AlaVal: 8.323 ± 0.128	2.027AlaTrp: 2.027 ± 0.061	2.842AlaTyr: 2.842 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	0.966CysAla: 0.966 ± 0.037	0.119CysCys: 0.119 ± 0.011	0.484CysAsp: 0.484 ± 0.026	0.485CysGlu: 0.485 ± 0.03	0.262CysPhe: 0.262 ± 0.018	0.988CysGly: 0.988 ± 0.041	0.377CysHis: 0.377 ± 0.028	0.332CysIle: 0.332 ± 0.02	0.316CysLys: 0.316 ± 0.018	0.983CysLeu: 0.983 ± 0.036	0.162CysMet: 0.162 ± 0.014	0.266CysAsn: 0.266 ± 0.019	0.656CysPro: 0.656 ± 0.031	0.331CysGln: 0.331 ± 0.018	0.772CysArg: 0.772 ± 0.032	0.445CysSer: 0.445 ± 0.027	0.414CysThr: 0.414 ± 0.023	0.606CysVal: 0.606 ± 0.033	0.105CysTrp: 0.105 ± 0.012	0.219CysTyr: 0.219 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.191AspAla: 6.191 ± 0.1	0.546AspCys: 0.546 ± 0.026	2.531AspAsp: 2.531 ± 0.065	3.388AspGlu: 3.388 ± 0.071	2.157AspPhe: 2.157 ± 0.05	4.22AspGly: 4.22 ± 0.114	1.118AspHis: 1.118 ± 0.039	2.795AspIle: 2.795 ± 0.066	2.196AspLys: 2.196 ± 0.06	5.858AspLeu: 5.858 ± 0.087	1.267AspMet: 1.267 ± 0.043	1.407AspAsn: 1.407 ± 0.084	2.783AspPro: 2.783 ± 0.067	1.585AspGln: 1.585 ± 0.049	3.439AspArg: 3.439 ± 0.072	2.269AspSer: 2.269 ± 0.05	2.449AspThr: 2.449 ± 0.148	3.396AspVal: 3.396 ± 0.073	1.068AspTrp: 1.068 ± 0.037	1.812AspTyr: 1.812 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	9.014GluAla: 9.014 ± 0.126	0.439GluCys: 0.439 ± 0.026	2.664GluAsp: 2.664 ± 0.054	3.247GluGlu: 3.247 ± 0.078	2.157GluPhe: 2.157 ± 0.058	4.252GluGly: 4.252 ± 0.074	1.512GluHis: 1.512 ± 0.044	3.523GluIle: 3.523 ± 0.07	2.453GluLys: 2.453 ± 0.062	7.009GluLeu: 7.009 ± 0.119	1.527GluMet: 1.527 ± 0.043	1.547GluAsn: 1.547 ± 0.068	2.778GluPro: 2.778 ± 0.063	2.912GluGln: 2.912 ± 0.061	5.248GluArg: 5.248 ± 0.091	2.554GluSer: 2.554 ± 0.058	3.089GluThr: 3.089 ± 0.074	4.533GluVal: 4.533 ± 0.069	0.811GluTrp: 0.811 ± 0.032	1.387GluTyr: 1.387 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.927PheAla: 3.927 ± 0.08	0.346PheCys: 0.346 ± 0.019	2.366PheAsp: 2.366 ± 0.056	2.258PheGlu: 2.258 ± 0.054	1.382PhePhe: 1.382 ± 0.046	3.166PheGly: 3.166 ± 0.07	0.762PheHis: 0.762 ± 0.034	1.666PheIle: 1.666 ± 0.05	1.232PheLys: 1.232 ± 0.041	3.339PheLeu: 3.339 ± 0.086	0.774PheMet: 0.774 ± 0.032	1.092PheAsn: 1.092 ± 0.039	1.442PhePro: 1.442 ± 0.045	1.092PheGln: 1.092 ± 0.034	2.018PheArg: 2.018 ± 0.047	1.955PheSer: 1.955 ± 0.052	1.743PheThr: 1.743 ± 0.05	2.559PheVal: 2.559 ± 0.064	0.508PheTrp: 0.508 ± 0.025	1.007PheTyr: 1.007 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	7.759GlyAla: 7.759 ± 0.123	0.916GlyCys: 0.916 ± 0.032	3.929GlyAsp: 3.929 ± 0.096	5.307GlyGlu: 5.307 ± 0.086	3.283GlyPhe: 3.283 ± 0.07	6.681GlyGly: 6.681 ± 0.135	2.067GlyHis: 2.067 ± 0.061	4.24GlyIle: 4.24 ± 0.075	3.654GlyLys: 3.654 ± 0.076	9.584GlyLeu: 9.584 ± 0.135	2.322GlyMet: 2.322 ± 0.066	2.288GlyAsn: 2.288 ± 0.217	2.69GlyPro: 2.69 ± 0.065	3.328GlyGln: 3.328 ± 0.069	6.121GlyArg: 6.121 ± 0.095	3.926GlySer: 3.926 ± 0.084	3.433GlyThr: 3.433 ± 0.152	5.941GlyVal: 5.941 ± 0.101	1.337GlyTrp: 1.337 ± 0.041	2.399GlyTyr: 2.399 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.565HisAla: 2.565 ± 0.059	0.299HisCys: 0.299 ± 0.02	1.241HisAsp: 1.241 ± 0.039	1.31HisGlu: 1.31 ± 0.045	0.898HisPhe: 0.898 ± 0.035	2.117HisGly: 2.117 ± 0.054	0.667HisHis: 0.667 ± 0.03	1.107HisIle: 1.107 ± 0.038	0.751HisLys: 0.751 ± 0.029	2.609HisLeu: 2.609 ± 0.066	0.43HisMet: 0.43 ± 0.026	0.636HisAsn: 0.636 ± 0.027	1.549HisPro: 1.549 ± 0.044	0.814HisGln: 0.814 ± 0.035	1.502HisArg: 1.502 ± 0.042	1.004HisSer: 1.004 ± 0.032	0.984HisThr: 0.984 ± 0.035	1.475HisVal: 1.475 ± 0.041	0.431HisTrp: 0.431 ± 0.026	0.794HisTyr: 0.794 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	6.137IleAla: 6.137 ± 0.096	0.427IleCys: 0.427 ± 0.024	3.235IleAsp: 3.235 ± 0.064	4.049IleGlu: 4.049 ± 0.073	1.335IlePhe: 1.335 ± 0.046	4.409IleGly: 4.409 ± 0.075	1.041IleHis: 1.041 ± 0.033	1.767IleIle: 1.767 ± 0.055	1.927IleLys: 1.927 ± 0.057	4.372IleLeu: 4.372 ± 0.082	0.91IleMet: 0.91 ± 0.034	1.537IleAsn: 1.537 ± 0.056	2.292IlePro: 2.292 ± 0.057	1.62IleGln: 1.62 ± 0.045	3.1IleArg: 3.1 ± 0.073	2.253IleSer: 2.253 ± 0.051	2.308IleThr: 2.308 ± 0.052	3.686IleVal: 3.686 ± 0.065	0.521IleTrp: 0.521 ± 0.026	1.215IleTyr: 1.215 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	4.68LysAla: 4.68 ± 0.112	0.236LysCys: 0.236 ± 0.018	1.954LysAsp: 1.954 ± 0.06	2.13LysGlu: 2.13 ± 0.059	0.953LysPhe: 0.953 ± 0.039	2.852LysGly: 2.852 ± 0.064	0.876LysHis: 0.876 ± 0.035	1.794LysIle: 1.794 ± 0.053	1.795LysLys: 1.795 ± 0.074	4.31LysLeu: 4.31 ± 0.073	0.959LysMet: 0.959 ± 0.038	1.055LysAsn: 1.055 ± 0.035	2.528LysPro: 2.528 ± 0.066	1.706LysGln: 1.706 ± 0.047	2.705LysArg: 2.705 ± 0.056	1.769LysSer: 1.769 ± 0.046	2.078LysThr: 2.078 ± 0.054	2.768LysVal: 2.768 ± 0.065	0.442LysTrp: 0.442 ± 0.027	0.804LysTyr: 0.804 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	16.085LeuAla: 16.085 ± 0.205	0.892LeuCys: 0.892 ± 0.031	6.561LeuAsp: 6.561 ± 0.09	6.083LeuGlu: 6.083 ± 0.118	3.806LeuPhe: 3.806 ± 0.078	8.529LeuGly: 8.529 ± 0.119	2.473LeuHis: 2.473 ± 0.065	5.596LeuIle: 5.596 ± 0.089	4.966LeuLys: 4.966 ± 0.092	12.047LeuLeu: 12.047 ± 0.197	2.497LeuMet: 2.497 ± 0.058	3.173LeuAsn: 3.173 ± 0.07	6.519LeuPro: 6.519 ± 0.122	3.632LeuGln: 3.632 ± 0.081	7.154LeuArg: 7.154 ± 0.118	5.954LeuSer: 5.954 ± 0.091	5.711LeuThr: 5.711 ± 0.114	7.208LeuVal: 7.208 ± 0.109	1.323LeuTrp: 1.323 ± 0.043	2.543LeuTyr: 2.543 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	3.114MetAla: 3.114 ± 0.066	0.143MetCys: 0.143 ± 0.013	1.186MetAsp: 1.186 ± 0.043	1.283MetGlu: 1.283 ± 0.043	0.654MetPhe: 0.654 ± 0.032	1.706MetGly: 1.706 ± 0.043	0.55MetHis: 0.55 ± 0.023	1.001MetIle: 1.001 ± 0.039	1.114MetLys: 1.114 ± 0.041	2.583MetLeu: 2.583 ± 0.061	0.497MetMet: 0.497 ± 0.027	0.761MetAsn: 0.761 ± 0.032	1.399MetPro: 1.399 ± 0.04	1.128MetGln: 1.128 ± 0.044	1.775MetArg: 1.775 ± 0.044	1.41MetSer: 1.41 ± 0.043	1.405MetThr: 1.405 ± 0.04	1.644MetVal: 1.644 ± 0.052	0.166MetTrp: 0.166 ± 0.016	0.389MetTyr: 0.389 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.97AsnAla: 2.97 ± 0.089	0.305AsnCys: 0.305 ± 0.021	1.312AsnAsp: 1.312 ± 0.097	1.452AsnGlu: 1.452 ± 0.04	0.928AsnPhe: 0.928 ± 0.036	2.084AsnGly: 2.084 ± 0.066	0.584AsnHis: 0.584 ± 0.026	1.384AsnIle: 1.384 ± 0.047	0.951AsnLys: 0.951 ± 0.036	3.26AsnLeu: 3.26 ± 0.084	0.642AsnMet: 0.642 ± 0.031	0.798AsnAsn: 0.798 ± 0.055	1.92AsnPro: 1.92 ± 0.054	1.043AsnGln: 1.043 ± 0.042	1.888AsnArg: 1.888 ± 0.052	1.128AsnSer: 1.128 ± 0.048	1.312AsnThr: 1.312 ± 0.059	1.954AsnVal: 1.954 ± 0.093	0.394AsnTrp: 0.394 ± 0.024	0.696AsnTyr: 0.696 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	6.698ProAla: 6.698 ± 0.127	0.385ProCys: 0.385 ± 0.026	3.072ProAsp: 3.072 ± 0.065	4.004ProGlu: 4.004 ± 0.077	1.758ProPhe: 1.758 ± 0.048	4.438ProGly: 4.438 ± 0.069	1.114ProHis: 1.114 ± 0.039	2.152ProIle: 2.152 ± 0.06	1.722ProLys: 1.722 ± 0.043	4.982ProLeu: 4.982 ± 0.079	1.19ProMet: 1.19 ± 0.032	1.351ProAsn: 1.351 ± 0.036	2.458ProPro: 2.458 ± 0.067	1.792ProGln: 1.792 ± 0.047	2.695ProArg: 2.695 ± 0.063	2.212ProSer: 2.212 ± 0.055	2.174ProThr: 2.174 ± 0.051	4.121ProVal: 4.121 ± 0.069	0.646ProTrp: 0.646 ± 0.028	1.326ProTyr: 1.326 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	6.066GlnAla: 6.066 ± 0.099	0.267GlnCys: 0.267 ± 0.018	1.79GlnAsp: 1.79 ± 0.047	2.071GlnGlu: 2.071 ± 0.052	1.247GlnPhe: 1.247 ± 0.041	3.07GlnGly: 3.07 ± 0.067	0.863GlnHis: 0.863 ± 0.035	1.966GlnIle: 1.966 ± 0.05	1.36GlnLys: 1.36 ± 0.044	3.993GlnLeu: 3.993 ± 0.079	0.986GlnMet: 0.986 ± 0.036	0.903GlnAsn: 0.903 ± 0.035	2.122GlnPro: 2.122 ± 0.059	1.538GlnGln: 1.538 ± 0.048	2.755GlnArg: 2.755 ± 0.066	1.713GlnSer: 1.713 ± 0.05	1.845GlnThr: 1.845 ± 0.051	2.893GlnVal: 2.893 ± 0.064	0.529GlnTrp: 0.529 ± 0.025	0.794GlnTyr: 0.794 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	7.617ArgAla: 7.617 ± 0.122	0.622ArgCys: 0.622 ± 0.03	3.35ArgAsp: 3.35 ± 0.06	4.715ArgGlu: 4.715 ± 0.084	2.864ArgPhe: 2.864 ± 0.056	4.45ArgGly: 4.45 ± 0.083	1.98ArgHis: 1.98 ± 0.049	3.896ArgIle: 3.896 ± 0.08	2.252ArgLys: 2.252 ± 0.055	9.382ArgLeu: 9.382 ± 0.165	1.755ArgMet: 1.755 ± 0.051	1.773ArgAsn: 1.773 ± 0.046	3.423ArgPro: 3.423 ± 0.065	3.435ArgGln: 3.435 ± 0.082	5.476ArgArg: 5.476 ± 0.104	2.791ArgSer: 2.791 ± 0.058	2.681ArgThr: 2.681 ± 0.058	4.723ArgVal: 4.723 ± 0.079	1.052ArgTrp: 1.052 ± 0.037	2.039ArgTyr: 2.039 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	5.016SerAla: 5.016 ± 0.082	0.447SerCys: 0.447 ± 0.024	2.213SerAsp: 2.213 ± 0.056	2.626SerGlu: 2.626 ± 0.057	1.729SerPhe: 1.729 ± 0.048	4.524SerGly: 4.524 ± 0.085	1.258SerHis: 1.258 ± 0.04	2.167SerIle: 2.167 ± 0.055	1.561SerLys: 1.561 ± 0.043	5.576SerLeu: 5.576 ± 0.1	1.022SerMet: 1.022 ± 0.039	1.299SerAsn: 1.299 ± 0.047	2.447SerPro: 2.447 ± 0.05	1.886SerGln: 1.886 ± 0.047	3.429SerArg: 3.429 ± 0.068	2.14SerSer: 2.14 ± 0.063	2.082SerThr: 2.082 ± 0.051	3.219SerVal: 3.219 ± 0.063	0.6SerTrp: 0.6 ± 0.028	1.21SerTyr: 1.21 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	5.293ThrAla: 5.293 ± 0.084	0.416ThrCys: 0.416 ± 0.025	2.427ThrAsp: 2.427 ± 0.068	2.677ThrGlu: 2.677 ± 0.065	1.357ThrPhe: 1.357 ± 0.046	4.621ThrGly: 4.621 ± 0.163	1.003ThrHis: 1.003 ± 0.038	1.904ThrIle: 1.904 ± 0.058	1.235ThrLys: 1.235 ± 0.041	5.953ThrLeu: 5.953 ± 0.147	0.879ThrMet: 0.879 ± 0.036	1.062ThrAsn: 1.062 ± 0.036	2.995ThrPro: 2.995 ± 0.076	1.57ThrGln: 1.57 ± 0.044	2.997ThrArg: 2.997 ± 0.065	2.027ThrSer: 2.027 ± 0.053	2.147ThrThr: 2.147 ± 0.059	3.795ThrVal: 3.795 ± 0.075	0.636ThrTrp: 0.636 ± 0.03	1.119ThrTyr: 1.119 ± 0.065	0.0ThrXaa: 0.0 ± 0.0
Val	8.47ValAla: 8.47 ± 0.123	0.736ValCys: 0.736 ± 0.035	3.791ValAsp: 3.791 ± 0.084	4.785ValGlu: 4.785 ± 0.09	2.54ValPhe: 2.54 ± 0.063	5.083ValGly: 5.083 ± 0.072	1.498ValHis: 1.498 ± 0.045	3.597ValIle: 3.597 ± 0.08	2.845ValLys: 2.845 ± 0.069	7.816ValLeu: 7.816 ± 0.126	1.852ValMet: 1.852 ± 0.048	2.096ValAsn: 2.096 ± 0.048	3.249ValPro: 3.249 ± 0.063	2.398ValGln: 2.398 ± 0.054	4.815ValArg: 4.815 ± 0.092	3.649ValSer: 3.649 ± 0.061	3.643ValThr: 3.643 ± 0.074	5.664ValVal: 5.664 ± 0.094	0.936ValTrp: 0.936 ± 0.035	1.671ValTyr: 1.671 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.352TrpAla: 1.352 ± 0.046	0.156TrpCys: 0.156 ± 0.014	0.611TrpAsp: 0.611 ± 0.028	0.599TrpGlu: 0.599 ± 0.027	0.536TrpPhe: 0.536 ± 0.024	0.854TrpGly: 0.854 ± 0.035	0.389TrpHis: 0.389 ± 0.025	0.571TrpIle: 0.571 ± 0.025	0.407TrpLys: 0.407 ± 0.02	2.439TrpLeu: 2.439 ± 0.066	0.312TrpMet: 0.312 ± 0.023	0.357TrpAsn: 0.357 ± 0.021	0.702TrpPro: 0.702 ± 0.033	0.959TrpGln: 0.959 ± 0.041	1.283TrpArg: 1.283 ± 0.05	0.599TrpSer: 0.599 ± 0.027	0.555TrpThr: 0.555 ± 0.024	0.944TrpVal: 0.944 ± 0.039	0.239TrpTrp: 0.239 ± 0.018	0.31TrpTyr: 0.31 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.823TyrAla: 2.823 ± 0.064	0.301TyrCys: 0.301 ± 0.019	1.467TyrAsp: 1.467 ± 0.048	1.294TyrGlu: 1.294 ± 0.04	0.993TyrPhe: 0.993 ± 0.033	2.283TyrGly: 2.283 ± 0.057	0.567TyrHis: 0.567 ± 0.028	0.951TyrIle: 0.951 ± 0.039	0.83TyrLys: 0.83 ± 0.04	2.873TyrLeu: 2.873 ± 0.067	0.461TyrMet: 0.461 ± 0.025	0.7TyrAsn: 0.7 ± 0.032	1.305TyrPro: 1.305 ± 0.036	1.101TyrGln: 1.101 ± 0.039	2.127TyrArg: 2.127 ± 0.046	1.253TyrSer: 1.253 ± 0.04	1.162TyrThr: 1.162 ± 0.053	1.681TyrVal: 1.681 ± 0.051	0.405TyrTrp: 0.405 ± 0.023	0.734TyrTyr: 0.734 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2668 proteins (822929 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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