Amino acid dipepetide frequency for Jeotgalicoccus saudimassiliensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.535AlaAla: 6.535 ± 0.153	0.456AlaCys: 0.456 ± 0.027	4.283AlaAsp: 4.283 ± 0.085	5.639AlaGlu: 5.639 ± 0.137	3.114AlaPhe: 3.114 ± 0.074	6.06AlaGly: 6.06 ± 0.11	1.38AlaHis: 1.38 ± 0.043	4.953AlaIle: 4.953 ± 0.1	3.854AlaLys: 3.854 ± 0.09	7.446AlaLeu: 7.446 ± 0.128	2.087AlaMet: 2.087 ± 0.063	2.328AlaAsn: 2.328 ± 0.071	2.142AlaPro: 2.142 ± 0.061	2.032AlaGln: 2.032 ± 0.064	2.709AlaArg: 2.709 ± 0.065	3.809AlaSer: 3.809 ± 0.083	3.109AlaThr: 3.109 ± 0.072	6.251AlaVal: 6.251 ± 0.114	0.42AlaTrp: 0.42 ± 0.027	2.206AlaTyr: 2.206 ± 0.062	0.0AlaXaa: 0.0 ± 0.0
Cys	0.311CysAla: 0.311 ± 0.023	0.052CysCys: 0.052 ± 0.012	0.343CysAsp: 0.343 ± 0.022	0.328CysGlu: 0.328 ± 0.022	0.159CysPhe: 0.159 ± 0.016	0.603CysGly: 0.603 ± 0.033	0.229CysHis: 0.229 ± 0.028	0.376CysIle: 0.376 ± 0.024	0.238CysLys: 0.238 ± 0.019	0.405CysLeu: 0.405 ± 0.025	0.102CysMet: 0.102 ± 0.012	0.179CysAsn: 0.179 ± 0.017	0.246CysPro: 0.246 ± 0.022	0.136CysGln: 0.136 ± 0.013	0.218CysArg: 0.218 ± 0.022	0.398CysSer: 0.398 ± 0.027	0.316CysThr: 0.316 ± 0.022	0.29CysVal: 0.29 ± 0.021	0.034CysTrp: 0.034 ± 0.007	0.153CysTyr: 0.153 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.1AspAla: 4.1 ± 0.085	0.289AspCys: 0.289 ± 0.021	3.926AspAsp: 3.926 ± 0.089	5.752AspGlu: 5.752 ± 0.103	2.974AspPhe: 2.974 ± 0.073	3.955AspGly: 3.955 ± 0.077	0.962AspHis: 0.962 ± 0.039	5.147AspIle: 5.147 ± 0.088	4.274AspLys: 4.274 ± 0.082	4.657AspLeu: 4.657 ± 0.088	1.784AspMet: 1.784 ± 0.049	2.978AspAsn: 2.978 ± 0.072	1.656AspPro: 1.656 ± 0.053	1.323AspGln: 1.323 ± 0.049	2.232AspArg: 2.232 ± 0.06	3.373AspSer: 3.373 ± 0.078	3.323AspThr: 3.323 ± 0.065	4.396AspVal: 4.396 ± 0.086	0.47AspTrp: 0.47 ± 0.026	2.775AspTyr: 2.775 ± 0.068	0.0AspXaa: 0.0 ± 0.0
Glu	5.668GluAla: 5.668 ± 0.101	0.296GluCys: 0.296 ± 0.022	4.717GluAsp: 4.717 ± 0.099	7.292GluGlu: 7.292 ± 0.165	2.917GluPhe: 2.917 ± 0.069	4.172GluGly: 4.172 ± 0.085	1.685GluHis: 1.685 ± 0.052	5.781GluIle: 5.781 ± 0.106	5.208GluLys: 5.208 ± 0.101	7.504GluLeu: 7.504 ± 0.114	2.371GluMet: 2.371 ± 0.058	4.189GluAsn: 4.189 ± 0.08	2.215GluPro: 2.215 ± 0.071	2.954GluGln: 2.954 ± 0.076	3.567GluArg: 3.567 ± 0.081	4.213GluSer: 4.213 ± 0.076	4.602GluThr: 4.602 ± 0.096	5.225GluVal: 5.225 ± 0.093	0.608GluTrp: 0.608 ± 0.033	2.836GluTyr: 2.836 ± 0.065	0.0GluXaa: 0.0 ± 0.0
Phe	2.775PheAla: 2.775 ± 0.067	0.224PheCys: 0.224 ± 0.019	2.861PheAsp: 2.861 ± 0.073	3.097PheGlu: 3.097 ± 0.065	2.136PhePhe: 2.136 ± 0.067	3.404PheGly: 3.404 ± 0.08	0.757PheHis: 0.757 ± 0.033	4.329PheIle: 4.329 ± 0.095	3.067PheLys: 3.067 ± 0.077	4.06PheLeu: 4.06 ± 0.092	1.397PheMet: 1.397 ± 0.05	2.743PheAsn: 2.743 ± 0.065	1.272PhePro: 1.272 ± 0.041	1.128PheGln: 1.128 ± 0.036	1.417PheArg: 1.417 ± 0.046	2.931PheSer: 2.931 ± 0.08	2.993PheThr: 2.993 ± 0.079	2.996PheVal: 2.996 ± 0.068	0.376PheTrp: 0.376 ± 0.024	1.642PheTyr: 1.642 ± 0.052	0.0PheXaa: 0.0 ± 0.0
Gly	5.072GlyAla: 5.072 ± 0.113	0.389GlyCys: 0.389 ± 0.024	3.651GlyAsp: 3.651 ± 0.068	4.889GlyGlu: 4.889 ± 0.093	3.271GlyPhe: 3.271 ± 0.064	4.88GlyGly: 4.88 ± 0.116	1.45GlyHis: 1.45 ± 0.042	6.033GlyIle: 6.033 ± 0.107	4.198GlyLys: 4.198 ± 0.084	6.486GlyLeu: 6.486 ± 0.122	2.178GlyMet: 2.178 ± 0.059	2.78GlyAsn: 2.78 ± 0.073	1.708GlyPro: 1.708 ± 0.059	1.917GlyGln: 1.917 ± 0.053	2.824GlyArg: 2.824 ± 0.076	4.073GlySer: 4.073 ± 0.068	4.357GlyThr: 4.357 ± 0.078	5.178GlyVal: 5.178 ± 0.093	0.575GlyTrp: 0.575 ± 0.032	2.78GlyTyr: 2.78 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.278HisAla: 1.278 ± 0.045	0.159HisCys: 0.159 ± 0.016	1.247HisAsp: 1.247 ± 0.046	1.52HisGlu: 1.52 ± 0.048	0.972HisPhe: 0.972 ± 0.036	1.519HisGly: 1.519 ± 0.048	0.591HisHis: 0.591 ± 0.035	1.72HisIle: 1.72 ± 0.042	1.033HisLys: 1.033 ± 0.037	1.951HisLeu: 1.951 ± 0.057	0.574HisMet: 0.574 ± 0.031	1.044HisAsn: 1.044 ± 0.044	1.049HisPro: 1.049 ± 0.046	0.611HisGln: 0.611 ± 0.032	0.862HisArg: 0.862 ± 0.038	1.168HisSer: 1.168 ± 0.046	1.117HisThr: 1.117 ± 0.045	1.33HisVal: 1.33 ± 0.052	0.166HisTrp: 0.166 ± 0.016	0.846HisTyr: 0.846 ± 0.039	0.0HisXaa: 0.0 ± 0.0
Ile	5.996IleAla: 5.996 ± 0.11	0.458IleCys: 0.458 ± 0.029	5.184IleAsp: 5.184 ± 0.082	5.88IleGlu: 5.88 ± 0.095	3.621IlePhe: 3.621 ± 0.085	5.923IleGly: 5.923 ± 0.132	1.548IleHis: 1.548 ± 0.056	7.104IleIle: 7.104 ± 0.142	4.625IleLys: 4.625 ± 0.086	6.93IleLeu: 6.93 ± 0.128	2.16IleMet: 2.16 ± 0.058	3.946IleAsn: 3.946 ± 0.076	3.128IlePro: 3.128 ± 0.078	2.152IleGln: 2.152 ± 0.056	2.85IleArg: 2.85 ± 0.078	5.166IleSer: 5.166 ± 0.102	4.876IleThr: 4.876 ± 0.092	5.727IleVal: 5.727 ± 0.106	0.534IleTrp: 0.534 ± 0.034	2.63IleTyr: 2.63 ± 0.063	0.0IleXaa: 0.0 ± 0.0
Lys	4.073LysAla: 4.073 ± 0.094	0.258LysCys: 0.258 ± 0.021	3.915LysAsp: 3.915 ± 0.076	5.878LysGlu: 5.878 ± 0.097	2.317LysPhe: 2.317 ± 0.063	3.442LysGly: 3.442 ± 0.081	1.446LysHis: 1.446 ± 0.045	4.444LysIle: 4.444 ± 0.09	4.79LysLys: 4.79 ± 0.098	5.431LysLeu: 5.431 ± 0.102	2.146LysMet: 2.146 ± 0.059	3.572LysAsn: 3.572 ± 0.083	1.917LysPro: 1.917 ± 0.053	2.045LysGln: 2.045 ± 0.051	2.964LysArg: 2.964 ± 0.066	3.433LysSer: 3.433 ± 0.08	3.586LysThr: 3.586 ± 0.082	4.277LysVal: 4.277 ± 0.08	0.452LysTrp: 0.452 ± 0.03	2.732LysTyr: 2.732 ± 0.072	0.0LysXaa: 0.0 ± 0.0
Leu	6.608LeuAla: 6.608 ± 0.112	0.415LeuCys: 0.415 ± 0.026	5.356LeuAsp: 5.356 ± 0.1	6.57LeuGlu: 6.57 ± 0.107	4.387LeuPhe: 4.387 ± 0.102	6.379LeuGly: 6.379 ± 0.123	1.661LeuHis: 1.661 ± 0.05	7.718LeuIle: 7.718 ± 0.158	6.04LeuLys: 6.04 ± 0.089	8.623LeuLeu: 8.623 ± 0.142	2.88LeuMet: 2.88 ± 0.067	5.021LeuAsn: 5.021 ± 0.096	3.43LeuPro: 3.43 ± 0.081	2.581LeuGln: 2.581 ± 0.074	3.209LeuArg: 3.209 ± 0.078	6.562LeuSer: 6.562 ± 0.115	5.811LeuThr: 5.811 ± 0.092	5.769LeuVal: 5.769 ± 0.106	0.601LeuTrp: 0.601 ± 0.035	3.375LeuTyr: 3.375 ± 0.072	0.0LeuXaa: 0.0 ± 0.0
Met	2.129MetAla: 2.129 ± 0.057	0.133MetCys: 0.133 ± 0.013	1.621MetAsp: 1.621 ± 0.045	1.801MetGlu: 1.801 ± 0.053	1.334MetPhe: 1.334 ± 0.049	1.787MetGly: 1.787 ± 0.052	0.583MetHis: 0.583 ± 0.034	2.361MetIle: 2.361 ± 0.061	2.242MetLys: 2.242 ± 0.056	2.804MetLeu: 2.804 ± 0.063	1.064MetMet: 1.064 ± 0.039	1.723MetAsn: 1.723 ± 0.056	1.134MetPro: 1.134 ± 0.043	0.977MetGln: 0.977 ± 0.04	1.159MetArg: 1.159 ± 0.042	2.016MetSer: 2.016 ± 0.058	2.184MetThr: 2.184 ± 0.059	1.681MetVal: 1.681 ± 0.051	0.165MetTrp: 0.165 ± 0.018	0.943MetTyr: 0.943 ± 0.035	0.0MetXaa: 0.0 ± 0.0
Asn	3.125AsnAla: 3.125 ± 0.065	0.22AsnCys: 0.22 ± 0.018	2.911AsnAsp: 2.911 ± 0.07	3.709AsnGlu: 3.709 ± 0.085	2.018AsnPhe: 2.018 ± 0.055	3.184AsnGly: 3.184 ± 0.074	1.113AsnHis: 1.113 ± 0.042	4.631AsnIle: 4.631 ± 0.089	3.073AsnLys: 3.073 ± 0.071	3.995AsnLeu: 3.995 ± 0.085	1.401AsnMet: 1.401 ± 0.048	2.685AsnAsn: 2.685 ± 0.079	2.0AsnPro: 2.0 ± 0.049	1.627AsnGln: 1.627 ± 0.054	2.035AsnArg: 2.035 ± 0.058	2.487AsnSer: 2.487 ± 0.064	2.735AsnThr: 2.735 ± 0.066	3.322AsnVal: 3.322 ± 0.079	0.374AsnTrp: 0.374 ± 0.024	2.035AsnTyr: 2.035 ± 0.062	0.0AsnXaa: 0.0 ± 0.0
Pro	2.59ProAla: 2.59 ± 0.069	0.145ProCys: 0.145 ± 0.015	2.186ProAsp: 2.186 ± 0.066	3.331ProGlu: 3.331 ± 0.082	1.734ProPhe: 1.734 ± 0.053	2.386ProGly: 2.386 ± 0.071	0.756ProHis: 0.756 ± 0.035	2.14ProIle: 2.14 ± 0.052	1.824ProLys: 1.824 ± 0.054	3.293ProLeu: 3.293 ± 0.071	0.887ProMet: 0.887 ± 0.038	1.296ProAsn: 1.296 ± 0.046	0.806ProPro: 0.806 ± 0.035	0.826ProGln: 0.826 ± 0.044	0.962ProArg: 0.962 ± 0.043	1.844ProSer: 1.844 ± 0.05	1.571ProThr: 1.571 ± 0.054	3.166ProVal: 3.166 ± 0.071	0.282ProTrp: 0.282 ± 0.02	1.319ProTyr: 1.319 ± 0.052	0.0ProXaa: 0.0 ± 0.0
Gln	1.978GlnAla: 1.978 ± 0.058	0.134GlnCys: 0.134 ± 0.015	1.621GlnAsp: 1.621 ± 0.048	2.186GlnGlu: 2.186 ± 0.071	1.432GlnPhe: 1.432 ± 0.053	1.702GlnGly: 1.702 ± 0.054	0.739GlnHis: 0.739 ± 0.033	2.065GlnIle: 2.065 ± 0.058	1.911GlnLys: 1.911 ± 0.061	3.05GlnLeu: 3.05 ± 0.068	1.012GlnMet: 1.012 ± 0.036	1.571GlnAsn: 1.571 ± 0.05	1.001GlnPro: 1.001 ± 0.038	1.159GlnGln: 1.159 ± 0.043	1.258GlnArg: 1.258 ± 0.052	1.849GlnSer: 1.849 ± 0.059	1.612GlnThr: 1.612 ± 0.05	1.803GlnVal: 1.803 ± 0.054	0.278GlnTrp: 0.278 ± 0.025	1.2GlnTyr: 1.2 ± 0.045	0.0GlnXaa: 0.0 ± 0.0
Arg	2.522ArgAla: 2.522 ± 0.068	0.272ArgCys: 0.272 ± 0.03	2.271ArgAsp: 2.271 ± 0.071	3.259ArgGlu: 3.259 ± 0.078	1.896ArgPhe: 1.896 ± 0.057	2.471ArgGly: 2.471 ± 0.061	0.853ArgHis: 0.853 ± 0.042	2.981ArgIle: 2.981 ± 0.07	2.709ArgLys: 2.709 ± 0.059	3.682ArgLeu: 3.682 ± 0.073	1.27ArgMet: 1.27 ± 0.045	1.861ArgAsn: 1.861 ± 0.052	1.288ArgPro: 1.288 ± 0.046	1.414ArgGln: 1.414 ± 0.053	1.946ArgArg: 1.946 ± 0.059	2.085ArgSer: 2.085 ± 0.057	2.221ArgThr: 2.221 ± 0.061	2.558ArgVal: 2.558 ± 0.064	0.241ArgTrp: 0.241 ± 0.019	1.525ArgTyr: 1.525 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	4.169SerAla: 4.169 ± 0.083	0.258SerCys: 0.258 ± 0.022	3.511SerAsp: 3.511 ± 0.067	4.404SerGlu: 4.404 ± 0.094	3.022SerPhe: 3.022 ± 0.069	4.845SerGly: 4.845 ± 0.092	1.307SerHis: 1.307 ± 0.046	4.689SerIle: 4.689 ± 0.093	3.592SerLys: 3.592 ± 0.079	5.677SerLeu: 5.677 ± 0.1	1.673SerMet: 1.673 ± 0.051	2.572SerAsn: 2.572 ± 0.065	1.865SerPro: 1.865 ± 0.062	1.763SerGln: 1.763 ± 0.054	2.491SerArg: 2.491 ± 0.067	3.699SerSer: 3.699 ± 0.083	3.102SerThr: 3.102 ± 0.073	4.244SerVal: 4.244 ± 0.094	0.516SerTrp: 0.516 ± 0.032	2.325SerTyr: 2.325 ± 0.069	0.0SerXaa: 0.0 ± 0.0
Thr	4.731ThrAla: 4.731 ± 0.091	0.276ThrCys: 0.276 ± 0.02	3.776ThrAsp: 3.776 ± 0.084	4.442ThrGlu: 4.442 ± 0.101	2.609ThrPhe: 2.609 ± 0.075	4.816ThrGly: 4.816 ± 0.103	1.227ThrHis: 1.227 ± 0.044	4.096ThrIle: 4.096 ± 0.078	3.006ThrLys: 3.006 ± 0.077	5.649ThrLeu: 5.649 ± 0.095	1.418ThrMet: 1.418 ± 0.05	2.273ThrAsn: 2.273 ± 0.062	2.389ThrPro: 2.389 ± 0.061	1.432ThrGln: 1.432 ± 0.053	2.064ThrArg: 2.064 ± 0.054	3.158ThrSer: 3.158 ± 0.072	3.068ThrThr: 3.068 ± 0.069	5.01ThrVal: 5.01 ± 0.116	0.418ThrTrp: 0.418 ± 0.023	2.044ThrTyr: 2.044 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	4.45ValAla: 4.45 ± 0.094	0.388ValCys: 0.388 ± 0.021	3.963ValAsp: 3.963 ± 0.079	4.92ValGlu: 4.92 ± 0.085	3.293ValPhe: 3.293 ± 0.065	4.247ValGly: 4.247 ± 0.089	1.441ValHis: 1.441 ± 0.053	6.303ValIle: 6.303 ± 0.114	4.601ValLys: 4.601 ± 0.099	7.055ValLeu: 7.055 ± 0.125	2.174ValMet: 2.174 ± 0.058	3.471ValAsn: 3.471 ± 0.076	2.593ValPro: 2.593 ± 0.07	2.004ValGln: 2.004 ± 0.055	2.658ValArg: 2.658 ± 0.063	4.721ValSer: 4.721 ± 0.085	4.691ValThr: 4.691 ± 0.082	4.874ValVal: 4.874 ± 0.098	0.501ValTrp: 0.501 ± 0.027	2.392ValTyr: 2.392 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.478TrpAla: 0.478 ± 0.032	0.055TrpCys: 0.055 ± 0.009	0.385TrpAsp: 0.385 ± 0.024	0.368TrpGlu: 0.368 ± 0.025	0.405TrpPhe: 0.405 ± 0.024	0.487TrpGly: 0.487 ± 0.034	0.211TrpHis: 0.211 ± 0.021	0.609TrpIle: 0.609 ± 0.029	0.36TrpLys: 0.36 ± 0.024	0.824TrpLeu: 0.824 ± 0.042	0.275TrpMet: 0.275 ± 0.022	0.363TrpAsn: 0.363 ± 0.024	0.212TrpPro: 0.212 ± 0.021	0.316TrpGln: 0.316 ± 0.02	0.295TrpArg: 0.295 ± 0.022	0.437TrpSer: 0.437 ± 0.027	0.459TrpThr: 0.459 ± 0.026	0.478TrpVal: 0.478 ± 0.028	0.069TrpTrp: 0.069 ± 0.01	0.301TrpTyr: 0.301 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.226TyrAla: 2.226 ± 0.062	0.238TyrCys: 0.238 ± 0.019	2.618TyrAsp: 2.618 ± 0.067	2.754TyrGlu: 2.754 ± 0.072	1.995TyrPhe: 1.995 ± 0.065	2.427TyrGly: 2.427 ± 0.062	0.82TyrHis: 0.82 ± 0.036	2.957TyrIle: 2.957 ± 0.072	2.473TyrLys: 2.473 ± 0.069	3.474TyrLeu: 3.474 ± 0.075	0.989TyrMet: 0.989 ± 0.039	2.087TyrAsn: 2.087 ± 0.058	1.291TyrPro: 1.291 ± 0.046	1.163TyrGln: 1.163 ± 0.041	1.607TyrArg: 1.607 ± 0.045	2.302TyrSer: 2.302 ± 0.057	2.168TyrThr: 2.168 ± 0.061	2.165TyrVal: 2.165 ± 0.059	0.305TyrTrp: 0.305 ± 0.023	1.542TyrTyr: 1.542 ± 0.06	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2181 proteins (655108 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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