Amino acid dipepetide frequency for Candidatus Tenderia electrophaga

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.131AlaAla: 13.131 ± 0.169	1.024AlaCys: 1.024 ± 0.032	6.072AlaAsp: 6.072 ± 0.076	7.018AlaGlu: 7.018 ± 0.104	3.388AlaPhe: 3.388 ± 0.066	8.526AlaGly: 8.526 ± 0.104	2.231AlaHis: 2.231 ± 0.044	5.274AlaIle: 5.274 ± 0.076	3.588AlaLys: 3.588 ± 0.071	12.136AlaLeu: 12.136 ± 0.128	2.946AlaMet: 2.946 ± 0.057	2.863AlaAsn: 2.863 ± 0.055	4.256AlaPro: 4.256 ± 0.074	4.789AlaGln: 4.789 ± 0.082	7.022AlaArg: 7.022 ± 0.091	4.864AlaSer: 4.864 ± 0.067	4.565AlaThr: 4.565 ± 0.078	7.828AlaVal: 7.828 ± 0.089	1.463AlaTrp: 1.463 ± 0.04	2.657AlaTyr: 2.657 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.91CysAla: 0.91 ± 0.031	0.135CysCys: 0.135 ± 0.011	0.568CysAsp: 0.568 ± 0.024	0.482CysGlu: 0.482 ± 0.022	0.354CysPhe: 0.354 ± 0.018	0.922CysGly: 0.922 ± 0.034	0.36CysHis: 0.36 ± 0.02	0.421CysIle: 0.421 ± 0.021	0.258CysLys: 0.258 ± 0.016	0.935CysLeu: 0.935 ± 0.032	0.184CysMet: 0.184 ± 0.014	0.295CysAsn: 0.295 ± 0.018	0.482CysPro: 0.482 ± 0.024	0.352CysGln: 0.352 ± 0.019	0.727CysArg: 0.727 ± 0.03	0.571CysSer: 0.571 ± 0.023	0.366CysThr: 0.366 ± 0.021	0.619CysVal: 0.619 ± 0.024	0.115CysTrp: 0.115 ± 0.017	0.273CysTyr: 0.273 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.124AspAla: 6.124 ± 0.077	0.488AspCys: 0.488 ± 0.024	3.534AspAsp: 3.534 ± 0.073	4.162AspGlu: 4.162 ± 0.071	2.204AspPhe: 2.204 ± 0.047	4.65AspGly: 4.65 ± 0.089	1.307AspHis: 1.307 ± 0.038	3.446AspIle: 3.446 ± 0.06	2.456AspLys: 2.456 ± 0.06	5.587AspLeu: 5.587 ± 0.07	1.578AspMet: 1.578 ± 0.042	1.982AspAsn: 1.982 ± 0.062	2.98AspPro: 2.98 ± 0.047	2.22AspGln: 2.22 ± 0.048	3.343AspArg: 3.343 ± 0.053	3.091AspSer: 3.091 ± 0.066	2.994AspThr: 2.994 ± 0.054	4.202AspVal: 4.202 ± 0.067	1.021AspTrp: 1.021 ± 0.035	2.1AspTyr: 2.1 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	6.704GluAla: 6.704 ± 0.112	0.447GluCys: 0.447 ± 0.022	2.955GluAsp: 2.955 ± 0.049	3.432GluGlu: 3.432 ± 0.069	2.219GluPhe: 2.219 ± 0.051	3.803GluGly: 3.803 ± 0.069	1.711GluHis: 1.711 ± 0.035	3.603GluIle: 3.603 ± 0.066	2.495GluLys: 2.495 ± 0.054	7.037GluLeu: 7.037 ± 0.095	1.673GluMet: 1.673 ± 0.04	1.835GluAsn: 1.835 ± 0.041	2.492GluPro: 2.492 ± 0.074	3.629GluGln: 3.629 ± 0.062	4.739GluArg: 4.739 ± 0.079	2.912GluSer: 2.912 ± 0.055	3.321GluThr: 3.321 ± 0.054	4.403GluVal: 4.403 ± 0.082	0.802GluTrp: 0.802 ± 0.024	1.659GluTyr: 1.659 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.447PheAla: 3.447 ± 0.064	0.394PheCys: 0.394 ± 0.018	2.608PheAsp: 2.608 ± 0.045	2.352PheGlu: 2.352 ± 0.043	1.477PhePhe: 1.477 ± 0.043	2.967PheGly: 2.967 ± 0.056	0.831PheHis: 0.831 ± 0.029	1.981PheIle: 1.981 ± 0.046	1.347PheLys: 1.347 ± 0.034	3.194PheLeu: 3.194 ± 0.064	0.905PheMet: 0.905 ± 0.028	1.398PheAsn: 1.398 ± 0.034	1.475PhePro: 1.475 ± 0.037	1.214PheGln: 1.214 ± 0.038	1.932PheArg: 1.932 ± 0.046	2.461PheSer: 2.461 ± 0.045	1.844PheThr: 1.844 ± 0.046	2.621PheVal: 2.621 ± 0.057	0.483PheTrp: 0.483 ± 0.026	1.117PheTyr: 1.117 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	7.128GlyAla: 7.128 ± 0.104	0.844GlyCys: 0.844 ± 0.028	4.516GlyAsp: 4.516 ± 0.07	4.944GlyGlu: 4.944 ± 0.07	3.146GlyPhe: 3.146 ± 0.058	5.991GlyGly: 5.991 ± 0.102	1.979GlyHis: 1.979 ± 0.052	4.247GlyIle: 4.247 ± 0.065	3.299GlyLys: 3.299 ± 0.063	8.095GlyLeu: 8.095 ± 0.095	2.372GlyMet: 2.372 ± 0.048	2.35GlyAsn: 2.35 ± 0.056	2.334GlyPro: 2.334 ± 0.051	3.015GlyGln: 3.015 ± 0.055	5.194GlyArg: 5.194 ± 0.073	3.946GlySer: 3.946 ± 0.069	3.709GlyThr: 3.709 ± 0.073	5.98GlyVal: 5.98 ± 0.076	1.21GlyTrp: 1.21 ± 0.037	2.491GlyTyr: 2.491 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.349HisAla: 2.349 ± 0.049	0.305HisCys: 0.305 ± 0.018	1.42HisAsp: 1.42 ± 0.039	1.352HisGlu: 1.352 ± 0.036	0.91HisPhe: 0.91 ± 0.027	2.059HisGly: 2.059 ± 0.045	0.762HisHis: 0.762 ± 0.029	1.334HisIle: 1.334 ± 0.04	0.829HisLys: 0.829 ± 0.032	2.394HisLeu: 2.394 ± 0.051	0.538HisMet: 0.538 ± 0.02	0.786HisAsn: 0.786 ± 0.03	1.435HisPro: 1.435 ± 0.041	1.001HisGln: 1.001 ± 0.033	1.565HisArg: 1.565 ± 0.033	1.384HisSer: 1.384 ± 0.033	1.155HisThr: 1.155 ± 0.031	1.469HisVal: 1.469 ± 0.042	0.45HisTrp: 0.45 ± 0.023	0.856HisTyr: 0.856 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.661IleAla: 5.661 ± 0.082	0.489IleCys: 0.489 ± 0.021	3.915IleAsp: 3.915 ± 0.06	3.938IleGlu: 3.938 ± 0.068	1.769IlePhe: 1.769 ± 0.047	4.37IleGly: 4.37 ± 0.078	1.28IleHis: 1.28 ± 0.034	2.744IleIle: 2.744 ± 0.062	2.284IleLys: 2.284 ± 0.05	4.589IleLeu: 4.589 ± 0.069	1.077IleMet: 1.077 ± 0.036	2.045IleAsn: 2.045 ± 0.048	2.42IlePro: 2.42 ± 0.051	1.875IleGln: 1.875 ± 0.042	3.062IleArg: 3.062 ± 0.054	3.169IleSer: 3.169 ± 0.055	2.888IleThr: 2.888 ± 0.056	3.534IleVal: 3.534 ± 0.066	0.508IleTrp: 0.508 ± 0.022	1.419IleTyr: 1.419 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	3.659LysAla: 3.659 ± 0.075	0.255LysCys: 0.255 ± 0.016	1.934LysAsp: 1.934 ± 0.048	2.112LysGlu: 2.112 ± 0.056	0.987LysPhe: 0.987 ± 0.034	2.674LysGly: 2.674 ± 0.055	1.008LysHis: 1.008 ± 0.033	1.981LysIle: 1.981 ± 0.045	1.703LysLys: 1.703 ± 0.082	3.836LysLeu: 3.836 ± 0.066	0.907LysMet: 0.907 ± 0.034	1.117LysAsn: 1.117 ± 0.036	1.893LysPro: 1.893 ± 0.046	2.173LysGln: 2.173 ± 0.051	2.829LysArg: 2.829 ± 0.048	1.815LysSer: 1.815 ± 0.043	2.024LysThr: 2.024 ± 0.044	2.669LysVal: 2.669 ± 0.069	0.363LysTrp: 0.363 ± 0.022	0.896LysTyr: 0.896 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	12.346LeuAla: 12.346 ± 0.134	1.008LeuCys: 1.008 ± 0.032	6.519LeuAsp: 6.519 ± 0.081	6.619LeuGlu: 6.619 ± 0.092	3.942LeuPhe: 3.942 ± 0.074	7.948LeuGly: 7.948 ± 0.099	2.341LeuHis: 2.341 ± 0.061	5.45LeuIle: 5.45 ± 0.076	4.269LeuLys: 4.269 ± 0.081	11.758LeuLeu: 11.758 ± 0.175	2.654LeuMet: 2.654 ± 0.054	3.491LeuAsn: 3.491 ± 0.057	5.347LeuPro: 5.347 ± 0.076	4.612LeuGln: 4.612 ± 0.077	6.987LeuArg: 6.987 ± 0.094	6.639LeuSer: 6.639 ± 0.081	5.176LeuThr: 5.176 ± 0.076	7.198LeuVal: 7.198 ± 0.1	1.315LeuTrp: 1.315 ± 0.049	2.647LeuTyr: 2.647 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.919MetAla: 2.919 ± 0.057	0.178MetCys: 0.178 ± 0.013	1.378MetAsp: 1.378 ± 0.039	1.442MetGlu: 1.442 ± 0.042	0.788MetPhe: 0.788 ± 0.025	1.795MetGly: 1.795 ± 0.048	0.522MetHis: 0.522 ± 0.022	1.334MetIle: 1.334 ± 0.035	1.099MetLys: 1.099 ± 0.033	2.676MetLeu: 2.676 ± 0.052	0.678MetMet: 0.678 ± 0.03	0.897MetAsn: 0.897 ± 0.032	1.381MetPro: 1.381 ± 0.038	1.108MetGln: 1.108 ± 0.036	1.582MetArg: 1.582 ± 0.04	1.647MetSer: 1.647 ± 0.04	1.39MetThr: 1.39 ± 0.039	1.779MetVal: 1.779 ± 0.038	0.183MetTrp: 0.183 ± 0.014	0.436MetTyr: 0.436 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.97AsnAla: 2.97 ± 0.058	0.314AsnCys: 0.314 ± 0.02	1.85AsnAsp: 1.85 ± 0.048	1.745AsnGlu: 1.745 ± 0.048	1.051AsnPhe: 1.051 ± 0.03	2.406AsnGly: 2.406 ± 0.06	0.684AsnHis: 0.684 ± 0.027	1.951AsnIle: 1.951 ± 0.039	1.144AsnLys: 1.144 ± 0.031	3.204AsnLeu: 3.204 ± 0.055	0.753AsnMet: 0.753 ± 0.026	1.187AsnAsn: 1.187 ± 0.048	1.893AsnPro: 1.893 ± 0.044	1.311AsnGln: 1.311 ± 0.035	1.966AsnArg: 1.966 ± 0.041	1.828AsnSer: 1.828 ± 0.089	1.644AsnThr: 1.644 ± 0.04	2.044AsnVal: 2.044 ± 0.051	0.428AsnTrp: 0.428 ± 0.022	0.924AsnTyr: 0.924 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	4.938ProAla: 4.938 ± 0.077	0.354ProCys: 0.354 ± 0.018	3.261ProAsp: 3.261 ± 0.055	3.49ProGlu: 3.49 ± 0.075	1.648ProPhe: 1.648 ± 0.037	3.841ProGly: 3.841 ± 0.066	1.077ProHis: 1.077 ± 0.032	2.003ProIle: 2.003 ± 0.047	1.452ProLys: 1.452 ± 0.038	4.941ProLeu: 4.941 ± 0.076	1.076ProMet: 1.076 ± 0.032	1.255ProAsn: 1.255 ± 0.036	2.22ProPro: 2.22 ± 0.053	2.069ProGln: 2.069 ± 0.047	2.476ProArg: 2.476 ± 0.055	2.101ProSer: 2.101 ± 0.043	1.958ProThr: 1.958 ± 0.042	3.647ProVal: 3.647 ± 0.058	0.663ProTrp: 0.663 ± 0.026	1.288ProTyr: 1.288 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	5.629GlnAla: 5.629 ± 0.089	0.335GlnCys: 0.335 ± 0.019	2.137GlnAsp: 2.137 ± 0.047	2.195GlnGlu: 2.195 ± 0.051	1.327GlnPhe: 1.327 ± 0.037	3.357GlnGly: 3.357 ± 0.057	1.269GlnHis: 1.269 ± 0.038	2.068GlnIle: 2.068 ± 0.045	1.262GlnLys: 1.262 ± 0.034	4.899GlnLeu: 4.899 ± 0.084	0.977GlnMet: 0.977 ± 0.031	1.09GlnAsn: 1.09 ± 0.038	2.011GlnPro: 2.011 ± 0.049	2.95GlnGln: 2.95 ± 0.077	3.843GlnArg: 3.843 ± 0.068	2.166GlnSer: 2.166 ± 0.05	2.132GlnThr: 2.132 ± 0.048	3.148GlnVal: 3.148 ± 0.056	0.642GlnTrp: 0.642 ± 0.023	0.995GlnTyr: 0.995 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	5.98ArgAla: 5.98 ± 0.082	0.638ArgCys: 0.638 ± 0.025	3.839ArgAsp: 3.839 ± 0.063	3.992ArgGlu: 3.992 ± 0.067	2.831ArgPhe: 2.831 ± 0.047	4.117ArgGly: 4.117 ± 0.068	2.017ArgHis: 2.017 ± 0.039	3.785ArgIle: 3.785 ± 0.055	2.292ArgLys: 2.292 ± 0.053	8.296ArgLeu: 8.296 ± 0.105	1.702ArgMet: 1.702 ± 0.036	2.009ArgAsn: 2.009 ± 0.043	2.806ArgPro: 2.806 ± 0.052	3.556ArgGln: 3.556 ± 0.062	5.16ArgArg: 5.16 ± 0.087	3.185ArgSer: 3.185 ± 0.053	2.373ArgThr: 2.373 ± 0.044	4.407ArgVal: 4.407 ± 0.069	1.002ArgTrp: 1.002 ± 0.029	2.242ArgTyr: 2.242 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	5.633SerAla: 5.633 ± 0.086	0.508SerCys: 0.508 ± 0.024	3.373SerAsp: 3.373 ± 0.081	3.137SerGlu: 3.137 ± 0.055	2.093SerPhe: 2.093 ± 0.048	5.206SerGly: 5.206 ± 0.075	1.355SerHis: 1.355 ± 0.036	2.785SerIle: 2.785 ± 0.055	1.728SerLys: 1.728 ± 0.04	5.829SerLeu: 5.829 ± 0.074	1.383SerMet: 1.383 ± 0.037	1.711SerAsn: 1.711 ± 0.049	2.404SerPro: 2.404 ± 0.048	2.054SerGln: 2.054 ± 0.045	3.372SerArg: 3.372 ± 0.054	3.077SerSer: 3.077 ± 0.065	2.48SerThr: 2.48 ± 0.062	3.747SerVal: 3.747 ± 0.062	0.701SerTrp: 0.701 ± 0.027	1.509SerTyr: 1.509 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.916ThrAla: 4.916 ± 0.083	0.407ThrCys: 0.407 ± 0.019	2.693ThrAsp: 2.693 ± 0.06	2.722ThrGlu: 2.722 ± 0.054	1.529ThrPhe: 1.529 ± 0.042	4.154ThrGly: 4.154 ± 0.07	1.105ThrHis: 1.105 ± 0.027	2.361ThrIle: 2.361 ± 0.051	1.324ThrLys: 1.324 ± 0.039	6.262ThrLeu: 6.262 ± 0.08	0.99ThrMet: 0.99 ± 0.033	1.347ThrAsn: 1.347 ± 0.04	2.937ThrPro: 2.937 ± 0.054	1.917ThrGln: 1.917 ± 0.042	3.008ThrArg: 3.008 ± 0.053	2.423ThrSer: 2.423 ± 0.061	2.447ThrThr: 2.447 ± 0.059	3.876ThrVal: 3.876 ± 0.068	0.597ThrTrp: 0.597 ± 0.024	1.206ThrTyr: 1.206 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	7.614ValAla: 7.614 ± 0.097	0.699ValCys: 0.699 ± 0.027	4.49ValAsp: 4.49 ± 0.066	4.633ValGlu: 4.633 ± 0.068	2.65ValPhe: 2.65 ± 0.054	4.975ValGly: 4.975 ± 0.086	1.37ValHis: 1.37 ± 0.035	4.392ValIle: 4.392 ± 0.069	2.738ValLys: 2.738 ± 0.06	7.425ValLeu: 7.425 ± 0.09	1.962ValMet: 1.962 ± 0.04	2.439ValAsn: 2.439 ± 0.057	3.059ValPro: 3.059 ± 0.054	2.386ValGln: 2.386 ± 0.048	4.078ValArg: 4.078 ± 0.067	4.43ValSer: 4.43 ± 0.078	3.845ValThr: 3.845 ± 0.076	5.754ValVal: 5.754 ± 0.103	0.854ValTrp: 0.854 ± 0.034	1.917ValTyr: 1.917 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.021TrpAla: 1.021 ± 0.033	0.166TrpCys: 0.166 ± 0.014	0.703TrpAsp: 0.703 ± 0.026	0.591TrpGlu: 0.591 ± 0.026	0.565TrpPhe: 0.565 ± 0.025	0.915TrpGly: 0.915 ± 0.03	0.406TrpHis: 0.406 ± 0.02	0.636TrpIle: 0.636 ± 0.023	0.357TrpLys: 0.357 ± 0.019	1.944TrpLeu: 1.944 ± 0.053	0.34TrpMet: 0.34 ± 0.016	0.377TrpAsn: 0.377 ± 0.021	0.638TrpPro: 0.638 ± 0.027	0.843TrpGln: 0.843 ± 0.031	1.166TrpArg: 1.166 ± 0.033	0.764TrpSer: 0.764 ± 0.026	0.526TrpThr: 0.526 ± 0.025	0.896TrpVal: 0.896 ± 0.028	0.252TrpTrp: 0.252 ± 0.015	0.368TrpTyr: 0.368 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.562TyrAla: 2.562 ± 0.044	0.341TyrCys: 0.341 ± 0.019	1.705TyrAsp: 1.705 ± 0.048	1.513TyrGlu: 1.513 ± 0.038	1.17TyrPhe: 1.17 ± 0.033	2.113TyrGly: 2.113 ± 0.048	0.738TyrHis: 0.738 ± 0.026	1.242TyrIle: 1.242 ± 0.033	0.91TyrLys: 0.91 ± 0.031	3.231TyrLeu: 3.231 ± 0.06	0.514TyrMet: 0.514 ± 0.024	0.825TyrAsn: 0.825 ± 0.03	1.295TyrPro: 1.295 ± 0.038	1.357TyrGln: 1.357 ± 0.035	2.182TyrArg: 2.182 ± 0.049	1.609TyrSer: 1.609 ± 0.049	1.383TyrThr: 1.383 ± 0.041	1.888TyrVal: 1.888 ± 0.049	0.423TyrTrp: 0.423 ± 0.021	0.946TyrTyr: 0.946 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3329 proteins (1089595 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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