Amino acid dipepetide frequency for Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.142AlaAla: 5.142 ± 0.046
0.99AlaCys: 0.99 ± 0.014
3.065AlaAsp: 3.065 ± 0.026
3.662AlaGlu: 3.662 ± 0.03
2.635AlaPhe: 2.635 ± 0.025
3.105AlaGly: 3.105 ± 0.028
1.445AlaHis: 1.445 ± 0.017
4.284AlaIle: 4.284 ± 0.028
4.161AlaLys: 4.161 ± 0.028
6.114AlaLeu: 6.114 ± 0.041
1.577AlaMet: 1.577 ± 0.016
2.995AlaAsn: 2.995 ± 0.024
2.731AlaPro: 2.731 ± 0.031
2.56AlaGln: 2.56 ± 0.024
3.068AlaArg: 3.068 ± 0.026
5.246AlaSer: 5.246 ± 0.039
3.804AlaThr: 3.804 ± 0.029
3.994AlaVal: 3.994 ± 0.03
0.706AlaTrp: 0.706 ± 0.012
2.106AlaTyr: 2.106 ± 0.02
0.0AlaXaa: 0.0 ± 0.0
Cys
0.721CysAla: 0.721 ± 0.012
0.313CysCys: 0.313 ± 0.008
0.718CysAsp: 0.718 ± 0.012
0.661CysGlu: 0.661 ± 0.012
0.702CysPhe: 0.702 ± 0.011
0.816CysGly: 0.816 ± 0.013
0.435CysHis: 0.435 ± 0.008
1.041CysIle: 1.041 ± 0.014
0.868CysLys: 0.868 ± 0.015
1.493CysLeu: 1.493 ± 0.018
0.366CysMet: 0.366 ± 0.008
0.648CysAsn: 0.648 ± 0.012
0.726CysPro: 0.726 ± 0.013
0.653CysGln: 0.653 ± 0.011
0.781CysArg: 0.781 ± 0.011
1.13CysSer: 1.13 ± 0.015
0.794CysThr: 0.794 ± 0.012
0.862CysVal: 0.862 ± 0.014
0.181CysTrp: 0.181 ± 0.006
0.507CysTyr: 0.507 ± 0.011
0.0CysXaa: 0.0 ± 0.0
Asp
3.28AspAla: 3.28 ± 0.028
0.756AspCys: 0.756 ± 0.011
4.03AspAsp: 4.03 ± 0.035
4.533AspGlu: 4.533 ± 0.039
2.229AspPhe: 2.229 ± 0.021
2.708AspGly: 2.708 ± 0.027
1.481AspHis: 1.481 ± 0.016
3.906AspIle: 3.906 ± 0.021
3.28AspLys: 3.28 ± 0.029
5.228AspLeu: 5.228 ± 0.031
1.377AspMet: 1.377 ± 0.016
2.737AspAsn: 2.737 ± 0.024
2.591AspPro: 2.591 ± 0.024
2.28AspGln: 2.28 ± 0.02
2.411AspArg: 2.411 ± 0.024
3.745AspSer: 3.745 ± 0.028
3.105AspThr: 3.105 ± 0.025
3.373AspVal: 3.373 ± 0.029
0.919AspTrp: 0.919 ± 0.014
2.114AspTyr: 2.114 ± 0.018
0.0AspXaa: 0.0 ± 0.0
Glu
4.263GluAla: 4.263 ± 0.033
0.765GluCys: 0.765 ± 0.013
4.277GluAsp: 4.277 ± 0.035
6.93GluGlu: 6.93 ± 0.078
2.23GluPhe: 2.23 ± 0.02
2.789GluGly: 2.789 ± 0.023
1.63GluHis: 1.63 ± 0.017
3.961GluIle: 3.961 ± 0.03
5.107GluLys: 5.107 ± 0.042
5.747GluLeu: 5.747 ± 0.041
1.538GluMet: 1.538 ± 0.016
3.364GluAsn: 3.364 ± 0.025
2.111GluPro: 2.111 ± 0.021
3.159GluGln: 3.159 ± 0.03
3.426GluArg: 3.426 ± 0.031
4.325GluSer: 4.325 ± 0.035
3.565GluThr: 3.565 ± 0.03
3.409GluVal: 3.409 ± 0.034
0.734GluTrp: 0.734 ± 0.013
2.165GluTyr: 2.165 ± 0.02
0.0GluXaa: 0.0 ± 0.0
Phe
2.476PheAla: 2.476 ± 0.024
0.709PheCys: 0.709 ± 0.012
2.566PheAsp: 2.566 ± 0.023
2.551PheGlu: 2.551 ± 0.024
1.737PhePhe: 1.737 ± 0.019
2.52PheGly: 2.52 ± 0.03
1.006PheHis: 1.006 ± 0.013
2.593PheIle: 2.593 ± 0.021
2.373PheLys: 2.373 ± 0.021
3.616PheLeu: 3.616 ± 0.029
1.051PheMet: 1.051 ± 0.013
2.031PheAsn: 2.031 ± 0.02
1.665PhePro: 1.665 ± 0.015
1.627PheGln: 1.627 ± 0.018
1.729PheArg: 1.729 ± 0.021
3.196PheSer: 3.196 ± 0.023
2.289PheThr: 2.289 ± 0.021
2.497PheVal: 2.497 ± 0.021
0.524PheTrp: 0.524 ± 0.01
1.431PheTyr: 1.431 ± 0.02
0.0PheXaa: 0.0 ± 0.0
Gly
2.939GlyAla: 2.939 ± 0.03
0.836GlyCys: 0.836 ± 0.011
2.413GlyAsp: 2.413 ± 0.021
2.531GlyGlu: 2.531 ± 0.024
2.384GlyPhe: 2.384 ± 0.024
3.102GlyGly: 3.102 ± 0.039
1.427GlyHis: 1.427 ± 0.017
3.257GlyIle: 3.257 ± 0.027
3.107GlyLys: 3.107 ± 0.026
4.575GlyLeu: 4.575 ± 0.033
1.132GlyMet: 1.132 ± 0.015
2.243GlyAsn: 2.243 ± 0.022
1.827GlyPro: 1.827 ± 0.02
1.864GlyGln: 1.864 ± 0.021
2.413GlyArg: 2.413 ± 0.026
4.101GlySer: 4.101 ± 0.032
2.796GlyThr: 2.796 ± 0.024
3.067GlyVal: 3.067 ± 0.025
0.689GlyTrp: 0.689 ± 0.011
2.156GlyTyr: 2.156 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
1.373HisAla: 1.373 ± 0.016
0.43HisCys: 0.43 ± 0.009
1.25HisAsp: 1.25 ± 0.017
1.318HisGlu: 1.318 ± 0.014
1.127HisPhe: 1.127 ± 0.014
1.294HisGly: 1.294 ± 0.017
1.036HisHis: 1.036 ± 0.014
1.643HisIle: 1.643 ± 0.017
1.575HisLys: 1.575 ± 0.019
2.568HisLeu: 2.568 ± 0.022
0.57HisMet: 0.57 ± 0.009
1.116HisAsn: 1.116 ± 0.018
1.518HisPro: 1.518 ± 0.017
1.339HisGln: 1.339 ± 0.017
1.509HisArg: 1.509 ± 0.018
1.961HisSer: 1.961 ± 0.018
1.45HisThr: 1.45 ± 0.017
1.473HisVal: 1.473 ± 0.017
0.366HisTrp: 0.366 ± 0.008
0.998HisTyr: 0.998 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
3.83IleAla: 3.83 ± 0.027
0.978IleCys: 0.978 ± 0.013
3.72IleAsp: 3.72 ± 0.028
4.29IleGlu: 4.29 ± 0.032
2.295IlePhe: 2.295 ± 0.022
2.942IleGly: 2.942 ± 0.028
1.795IleHis: 1.795 ± 0.017
3.676IleIle: 3.676 ± 0.027
4.223IleLys: 4.223 ± 0.032
5.556IleLeu: 5.556 ± 0.034
1.402IleMet: 1.402 ± 0.017
3.141IleAsn: 3.141 ± 0.026
3.234IlePro: 3.234 ± 0.024
2.999IleGln: 2.999 ± 0.027
3.044IleArg: 3.044 ± 0.022
4.736IleSer: 4.736 ± 0.028
3.496IleThr: 3.496 ± 0.025
3.645IleVal: 3.645 ± 0.033
0.73IleTrp: 0.73 ± 0.013
2.07IleTyr: 2.07 ± 0.018
0.0IleXaa: 0.0 ± 0.0
Lys
4.374LysAla: 4.374 ± 0.032
0.861LysCys: 0.861 ± 0.012
3.686LysAsp: 3.686 ± 0.03
5.459LysGlu: 5.459 ± 0.047
2.182LysPhe: 2.182 ± 0.02
2.891LysGly: 2.891 ± 0.023
1.753LysHis: 1.753 ± 0.017
3.746LysIle: 3.746 ± 0.026
6.335LysLys: 6.335 ± 0.059
5.717LysLeu: 5.717 ± 0.033
1.588LysMet: 1.588 ± 0.017
3.453LysAsn: 3.453 ± 0.027
2.867LysPro: 2.867 ± 0.026
3.136LysGln: 3.136 ± 0.027
4.359LysArg: 4.359 ± 0.033
4.842LysSer: 4.842 ± 0.033
3.801LysThr: 3.801 ± 0.026
3.816LysVal: 3.816 ± 0.031
0.72LysTrp: 0.72 ± 0.012
2.341LysTyr: 2.341 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
5.953LeuAla: 5.953 ± 0.036
1.423LeuCys: 1.423 ± 0.016
5.417LeuAsp: 5.417 ± 0.035
5.805LeuGlu: 5.805 ± 0.048
3.723LeuPhe: 3.723 ± 0.029
4.569LeuGly: 4.569 ± 0.032
2.157LeuHis: 2.157 ± 0.018
4.903LeuIle: 4.903 ± 0.029
6.511LeuLys: 6.511 ± 0.043
8.979LeuLeu: 8.979 ± 0.048
2.26LeuMet: 2.26 ± 0.022
4.558LeuAsn: 4.558 ± 0.031
4.88LeuPro: 4.88 ± 0.035
4.116LeuGln: 4.116 ± 0.033
4.527LeuArg: 4.527 ± 0.031
7.874LeuSer: 7.874 ± 0.038
5.114LeuThr: 5.114 ± 0.033
5.239LeuVal: 5.239 ± 0.031
1.059LeuTrp: 1.059 ± 0.016
3.027LeuTyr: 3.027 ± 0.023
0.0LeuXaa: 0.0 ± 0.0
Met
1.707MetAla: 1.707 ± 0.018
0.279MetCys: 0.279 ± 0.007
1.548MetAsp: 1.548 ± 0.017
1.52MetGlu: 1.52 ± 0.017
0.878MetPhe: 0.878 ± 0.014
1.085MetGly: 1.085 ± 0.014
0.548MetHis: 0.548 ± 0.009
1.48MetIle: 1.48 ± 0.016
1.668MetLys: 1.668 ± 0.017
1.997MetLeu: 1.997 ± 0.017
0.787MetMet: 0.787 ± 0.014
1.403MetAsn: 1.403 ± 0.015
1.139MetPro: 1.139 ± 0.014
0.916MetGln: 0.916 ± 0.013
1.045MetArg: 1.045 ± 0.015
2.148MetSer: 2.148 ± 0.019
1.624MetThr: 1.624 ± 0.016
1.553MetVal: 1.553 ± 0.016
0.233MetTrp: 0.233 ± 0.006
0.71MetTyr: 0.71 ± 0.012
0.0MetXaa: 0.0 ± 0.0
Asn
3.124AsnAla: 3.124 ± 0.027
0.663AsnCys: 0.663 ± 0.011
2.886AsnAsp: 2.886 ± 0.023
3.206AsnGlu: 3.206 ± 0.026
1.685AsnPhe: 1.685 ± 0.017
2.606AsnGly: 2.606 ± 0.027
1.298AsnHis: 1.298 ± 0.016
3.226AsnIle: 3.226 ± 0.03
3.415AsnLys: 3.415 ± 0.03
4.102AsnLeu: 4.102 ± 0.026
1.311AsnMet: 1.311 ± 0.016
3.453AsnAsn: 3.453 ± 0.038
2.364AsnPro: 2.364 ± 0.022
2.268AsnGln: 2.268 ± 0.025
2.38AsnArg: 2.38 ± 0.021
3.825AsnSer: 3.825 ± 0.029
3.085AsnThr: 3.085 ± 0.026
3.003AsnVal: 3.003 ± 0.027
0.665AsnTrp: 0.665 ± 0.012
1.776AsnTyr: 1.776 ± 0.019
0.0AsnXaa: 0.0 ± 0.0
Pro
2.846ProAla: 2.846 ± 0.027
0.559ProCys: 0.559 ± 0.012
2.391ProAsp: 2.391 ± 0.019
2.965ProGlu: 2.965 ± 0.021
2.104ProPhe: 2.104 ± 0.022
2.087ProGly: 2.087 ± 0.021
1.074ProHis: 1.074 ± 0.015
3.006ProIle: 3.006 ± 0.027
3.012ProLys: 3.012 ± 0.025
4.192ProLeu: 4.192 ± 0.027
1.008ProMet: 1.008 ± 0.015
2.301ProAsn: 2.301 ± 0.024
3.098ProPro: 3.098 ± 0.053
1.843ProGln: 1.843 ± 0.025
2.037ProArg: 2.037 ± 0.022
4.655ProSer: 4.655 ± 0.041
3.275ProThr: 3.275 ± 0.029
3.066ProVal: 3.066 ± 0.029
0.466ProTrp: 0.466 ± 0.01
1.578ProTyr: 1.578 ± 0.018
0.0ProXaa: 0.0 ± 0.0
Gln
2.753GlnAla: 2.753 ± 0.025
0.537GlnCys: 0.537 ± 0.012
2.202GlnAsp: 2.202 ± 0.023
3.104GlnGlu: 3.104 ± 0.03
1.697GlnPhe: 1.697 ± 0.018
1.892GlnGly: 1.892 ± 0.021
1.325GlnHis: 1.325 ± 0.016
2.388GlnIle: 2.388 ± 0.023
2.874GlnLys: 2.874 ± 0.026
4.289GlnLeu: 4.289 ± 0.032
1.089GlnMet: 1.089 ± 0.014
1.986GlnAsn: 1.986 ± 0.021
2.195GlnPro: 2.195 ± 0.03
3.947GlnGln: 3.947 ± 0.088
2.351GlnArg: 2.351 ± 0.023
3.23GlnSer: 3.23 ± 0.027
2.365GlnThr: 2.365 ± 0.021
2.575GlnVal: 2.575 ± 0.025
0.543GlnTrp: 0.543 ± 0.009
1.501GlnTyr: 1.501 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
2.979ArgAla: 2.979 ± 0.026
0.693ArgCys: 0.693 ± 0.013
2.316ArgAsp: 2.316 ± 0.022
2.877ArgGlu: 2.877 ± 0.027
2.142ArgPhe: 2.142 ± 0.019
2.195ArgGly: 2.195 ± 0.027
1.417ArgHis: 1.417 ± 0.017
3.034ArgIle: 3.034 ± 0.023
3.887ArgLys: 3.887 ± 0.028
5.126ArgLeu: 5.126 ± 0.032
1.278ArgMet: 1.278 ± 0.016
2.355ArgAsn: 2.355 ± 0.019
2.44ArgPro: 2.44 ± 0.026
2.353ArgGln: 2.353 ± 0.022
3.479ArgArg: 3.479 ± 0.036
3.905ArgSer: 3.905 ± 0.032
2.627ArgThr: 2.627 ± 0.022
2.767ArgVal: 2.767 ± 0.026
0.687ArgTrp: 0.687 ± 0.01
1.827ArgTyr: 1.827 ± 0.019
0.0ArgXaa: 0.0 ± 0.0
Ser
4.962SerAla: 4.962 ± 0.038
1.057SerCys: 1.057 ± 0.014
4.298SerAsp: 4.298 ± 0.03
4.24SerGlu: 4.24 ± 0.036
3.525SerPhe: 3.525 ± 0.027
3.756SerGly: 3.756 ± 0.03
1.929SerHis: 1.929 ± 0.019
5.208SerIle: 5.208 ± 0.033
5.002SerLys: 5.002 ± 0.032
7.532SerLeu: 7.532 ± 0.041
1.837SerMet: 1.837 ± 0.017
4.196SerAsn: 4.196 ± 0.029
4.005SerPro: 4.005 ± 0.037
3.147SerGln: 3.147 ± 0.025
3.89SerArg: 3.89 ± 0.033
8.981SerSer: 8.981 ± 0.085
5.585SerThr: 5.585 ± 0.045
4.72SerVal: 4.72 ± 0.037
0.902SerTrp: 0.902 ± 0.012
2.372SerTyr: 2.372 ± 0.021
0.0SerXaa: 0.0 ± 0.0
Thr
4.036ThrAla: 4.036 ± 0.031
0.791ThrCys: 0.791 ± 0.012
2.898ThrAsp: 2.898 ± 0.021
3.448ThrGlu: 3.448 ± 0.03
2.443ThrPhe: 2.443 ± 0.02
3.054ThrGly: 3.054 ± 0.026
1.346ThrHis: 1.346 ± 0.016
3.959ThrIle: 3.959 ± 0.028
3.76ThrLys: 3.76 ± 0.026
5.305ThrLeu: 5.305 ± 0.029
1.393ThrMet: 1.393 ± 0.015
2.888ThrAsn: 2.888 ± 0.026
3.18ThrPro: 3.18 ± 0.031
2.189ThrGln: 2.189 ± 0.024
2.694ThrArg: 2.694 ± 0.024
5.089ThrSer: 5.089 ± 0.039
4.509ThrThr: 4.509 ± 0.053
3.855ThrVal: 3.855 ± 0.032
0.746ThrTrp: 0.746 ± 0.012
1.718ThrTyr: 1.718 ± 0.016
0.0ThrXaa: 0.0 ± 0.0
Val
3.833ValAla: 3.833 ± 0.026
0.943ValCys: 0.943 ± 0.012
3.691ValAsp: 3.691 ± 0.028
3.749ValGlu: 3.749 ± 0.03
2.429ValPhe: 2.429 ± 0.019
2.905ValGly: 2.905 ± 0.029
1.548ValHis: 1.548 ± 0.017
3.694ValIle: 3.694 ± 0.029
3.894ValLys: 3.894 ± 0.032
5.497ValLeu: 5.497 ± 0.034
1.492ValMet: 1.492 ± 0.016
3.013ValAsn: 3.013 ± 0.026
2.956ValPro: 2.956 ± 0.023
2.408ValGln: 2.408 ± 0.021
2.713ValArg: 2.713 ± 0.023
4.583ValSer: 4.583 ± 0.035
3.358ValThr: 3.358 ± 0.031
3.865ValVal: 3.865 ± 0.033
0.756ValTrp: 0.756 ± 0.014
2.059ValTyr: 2.059 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
0.721TrpAla: 0.721 ± 0.011
0.206TrpCys: 0.206 ± 0.005
0.702TrpAsp: 0.702 ± 0.012
0.61TrpGlu: 0.61 ± 0.011
0.55TrpPhe: 0.55 ± 0.009
0.6TrpGly: 0.6 ± 0.01
0.304TrpHis: 0.304 ± 0.008
0.747TrpIle: 0.747 ± 0.012
0.908TrpLys: 0.908 ± 0.015
1.134TrpLeu: 1.134 ± 0.018
0.334TrpMet: 0.334 ± 0.007
0.699TrpAsn: 0.699 ± 0.01
0.482TrpPro: 0.482 ± 0.01
0.455TrpGln: 0.455 ± 0.01
0.76TrpArg: 0.76 ± 0.013
1.057TrpSer: 1.057 ± 0.015
0.805TrpThr: 0.805 ± 0.013
0.623TrpVal: 0.623 ± 0.012
0.191TrpTrp: 0.191 ± 0.006
0.421TrpTyr: 0.421 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.074TyrAla: 2.074 ± 0.02
0.631TyrCys: 0.631 ± 0.012
2.008TyrAsp: 2.008 ± 0.021
2.034TyrGlu: 2.034 ± 0.02
1.487TyrPhe: 1.487 ± 0.017
1.942TyrGly: 1.942 ± 0.021
0.962TyrHis: 0.962 ± 0.012
2.049TyrIle: 2.049 ± 0.022
1.968TyrLys: 1.968 ± 0.019
3.329TyrLeu: 3.329 ± 0.026
0.877TyrMet: 0.877 ± 0.013
1.762TyrAsn: 1.762 ± 0.021
1.554TyrPro: 1.554 ± 0.018
1.584TyrGln: 1.584 ± 0.02
1.766TyrArg: 1.766 ± 0.019
2.514TyrSer: 2.514 ± 0.023
1.856TyrThr: 1.856 ± 0.019
1.986TyrVal: 1.986 ± 0.019
0.492TyrTrp: 0.492 ± 0.01
1.416TyrTyr: 1.416 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 16971 proteins (5840663 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski