Amino acid dipepetide frequency for Jatropha curcas (Barbados nut)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.214AlaAla: 6.214 ± 0.037	1.262AlaCys: 1.262 ± 0.011	3.113AlaAsp: 3.113 ± 0.02	4.255AlaGlu: 4.255 ± 0.025	2.749AlaPhe: 2.749 ± 0.021	4.215AlaGly: 4.215 ± 0.024	1.332AlaHis: 1.332 ± 0.013	4.012AlaIle: 4.012 ± 0.023	3.863AlaLys: 3.863 ± 0.023	6.601AlaLeu: 6.601 ± 0.028	1.794AlaMet: 1.794 ± 0.014	2.702AlaAsn: 2.702 ± 0.017	2.841AlaPro: 2.841 ± 0.02	2.204AlaGln: 2.204 ± 0.017	3.615AlaArg: 3.615 ± 0.022	5.951AlaSer: 5.951 ± 0.028	3.636AlaThr: 3.636 ± 0.018	4.595AlaVal: 4.595 ± 0.026	0.851AlaTrp: 0.851 ± 0.01	1.917AlaTyr: 1.917 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	0.994CysAla: 0.994 ± 0.01	0.518CysCys: 0.518 ± 0.008	0.831CysAsp: 0.831 ± 0.011	0.866CysGlu: 0.866 ± 0.009	0.891CysPhe: 0.891 ± 0.01	1.295CysGly: 1.295 ± 0.015	0.461CysHis: 0.461 ± 0.007	0.995CysIle: 0.995 ± 0.01	1.155CysLys: 1.155 ± 0.015	1.809CysLeu: 1.809 ± 0.016	0.44CysMet: 0.44 ± 0.007	0.844CysAsn: 0.844 ± 0.011	0.987CysPro: 0.987 ± 0.013	0.603CysGln: 0.603 ± 0.008	0.99CysArg: 0.99 ± 0.011	1.739CysSer: 1.739 ± 0.015	0.876CysThr: 0.876 ± 0.01	0.983CysVal: 0.983 ± 0.01	0.262CysTrp: 0.262 ± 0.005	0.539CysTyr: 0.539 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.447AspAla: 3.447 ± 0.023	0.965AspCys: 0.965 ± 0.011	3.515AspAsp: 3.515 ± 0.026	3.928AspGlu: 3.928 ± 0.023	2.494AspPhe: 2.494 ± 0.015	3.682AspGly: 3.682 ± 0.022	1.19AspHis: 1.19 ± 0.012	3.071AspIle: 3.071 ± 0.019	2.734AspLys: 2.734 ± 0.019	5.12AspLeu: 5.12 ± 0.026	1.335AspMet: 1.335 ± 0.011	2.13AspAsn: 2.13 ± 0.017	2.713AspPro: 2.713 ± 0.016	1.755AspGln: 1.755 ± 0.014	2.542AspArg: 2.542 ± 0.019	4.202AspSer: 4.202 ± 0.023	2.252AspThr: 2.252 ± 0.015	3.415AspVal: 3.415 ± 0.018	0.741AspTrp: 0.741 ± 0.009	1.612AspTyr: 1.612 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	4.772GluAla: 4.772 ± 0.025	0.846GluCys: 0.846 ± 0.011	4.018GluAsp: 4.018 ± 0.024	6.721GluGlu: 6.721 ± 0.05	2.392GluPhe: 2.392 ± 0.017	3.756GluGly: 3.756 ± 0.02	1.234GluHis: 1.234 ± 0.012	4.042GluIle: 4.042 ± 0.027	5.036GluLys: 5.036 ± 0.037	6.022GluLeu: 6.022 ± 0.03	1.914GluMet: 1.914 ± 0.015	3.172GluAsn: 3.172 ± 0.021	2.113GluPro: 2.113 ± 0.016	2.186GluGln: 2.186 ± 0.016	3.525GluArg: 3.525 ± 0.022	4.57GluSer: 4.57 ± 0.023	3.162GluThr: 3.162 ± 0.019	4.23GluVal: 4.23 ± 0.024	0.73GluTrp: 0.73 ± 0.008	1.706GluTyr: 1.706 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	2.5PheAla: 2.5 ± 0.017	0.898PheCys: 0.898 ± 0.011	2.477PheAsp: 2.477 ± 0.017	2.396PheGlu: 2.396 ± 0.016	1.931PhePhe: 1.931 ± 0.015	3.117PheGly: 3.117 ± 0.021	1.041PheHis: 1.041 ± 0.01	2.143PheIle: 2.143 ± 0.016	2.133PheLys: 2.133 ± 0.014	4.385PheLeu: 4.385 ± 0.027	0.981PheMet: 0.981 ± 0.01	1.829PheAsn: 1.829 ± 0.015	2.112PhePro: 2.112 ± 0.016	1.601PheGln: 1.601 ± 0.014	2.029PheArg: 2.029 ± 0.015	4.0PheSer: 4.0 ± 0.024	2.035PheThr: 2.035 ± 0.019	2.548PheVal: 2.548 ± 0.017	0.596PheTrp: 0.596 ± 0.008	1.295PheTyr: 1.295 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	3.857GlyAla: 3.857 ± 0.024	1.275GlyCys: 1.275 ± 0.014	3.406GlyAsp: 3.406 ± 0.027	3.699GlyGlu: 3.699 ± 0.023	3.221GlyPhe: 3.221 ± 0.021	5.327GlyGly: 5.327 ± 0.067	1.491GlyHis: 1.491 ± 0.015	3.796GlyIle: 3.796 ± 0.024	4.123GlyLys: 4.123 ± 0.024	5.946GlyLeu: 5.946 ± 0.027	1.55GlyMet: 1.55 ± 0.014	3.245GlyAsn: 3.245 ± 0.034	2.592GlyPro: 2.592 ± 0.019	2.048GlyGln: 2.048 ± 0.017	3.559GlyArg: 3.559 ± 0.022	5.857GlySer: 5.857 ± 0.03	3.309GlyThr: 3.309 ± 0.021	3.962GlyVal: 3.962 ± 0.024	0.893GlyTrp: 0.893 ± 0.017	2.094GlyTyr: 2.094 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.385HisAla: 1.385 ± 0.013	0.527HisCys: 0.527 ± 0.007	1.056HisAsp: 1.056 ± 0.011	1.208HisGlu: 1.208 ± 0.013	1.08HisPhe: 1.08 ± 0.011	1.7HisGly: 1.7 ± 0.014	0.957HisHis: 0.957 ± 0.015	1.166HisIle: 1.166 ± 0.011	1.149HisLys: 1.149 ± 0.012	2.353HisLeu: 2.353 ± 0.018	0.555HisMet: 0.555 ± 0.007	1.013HisAsn: 1.013 ± 0.009	1.331HisPro: 1.331 ± 0.012	1.004HisGln: 1.004 ± 0.01	1.361HisArg: 1.361 ± 0.012	1.858HisSer: 1.858 ± 0.016	1.021HisThr: 1.021 ± 0.011	1.44HisVal: 1.44 ± 0.013	0.28HisTrp: 0.28 ± 0.005	0.711HisTyr: 0.711 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.73IleAla: 3.73 ± 0.021	1.091IleCys: 1.091 ± 0.011	3.033IleAsp: 3.033 ± 0.018	3.429IleGlu: 3.429 ± 0.022	2.354IlePhe: 2.354 ± 0.018	3.583IleGly: 3.583 ± 0.025	1.278IleHis: 1.278 ± 0.012	2.987IleIle: 2.987 ± 0.021	3.046IleLys: 3.046 ± 0.018	5.279IleLeu: 5.279 ± 0.028	1.189IleMet: 1.189 ± 0.012	2.311IleAsn: 2.311 ± 0.015	3.267IlePro: 3.267 ± 0.028	2.025IleGln: 2.025 ± 0.014	2.709IleArg: 2.709 ± 0.019	5.018IleSer: 5.018 ± 0.026	2.687IleThr: 2.687 ± 0.018	3.447IleVal: 3.447 ± 0.021	0.717IleTrp: 0.717 ± 0.009	1.543IleTyr: 1.543 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.052LysAla: 4.052 ± 0.027	0.947LysCys: 0.947 ± 0.01	3.231LysAsp: 3.231 ± 0.018	5.001LysGlu: 5.001 ± 0.036	2.162LysPhe: 2.162 ± 0.016	3.605LysGly: 3.605 ± 0.022	1.342LysHis: 1.342 ± 0.013	3.345LysIle: 3.345 ± 0.018	4.932LysLys: 4.932 ± 0.038	5.936LysLeu: 5.936 ± 0.025	1.496LysMet: 1.496 ± 0.013	2.809LysAsn: 2.809 ± 0.02	2.742LysPro: 2.742 ± 0.02	2.284LysGln: 2.284 ± 0.018	3.577LysArg: 3.577 ± 0.025	4.535LysSer: 4.535 ± 0.028	2.756LysThr: 2.756 ± 0.018	3.752LysVal: 3.752 ± 0.024	0.777LysTrp: 0.777 ± 0.01	1.624LysTyr: 1.624 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	6.628LeuAla: 6.628 ± 0.028	1.794LeuCys: 1.794 ± 0.015	5.276LeuAsp: 5.276 ± 0.028	6.447LeuGlu: 6.447 ± 0.033	3.754LeuPhe: 3.754 ± 0.024	5.833LeuGly: 5.833 ± 0.027	2.541LeuHis: 2.541 ± 0.018	4.78LeuIle: 4.78 ± 0.025	6.128LeuLys: 6.128 ± 0.029	9.769LeuLeu: 9.769 ± 0.045	2.128LeuMet: 2.128 ± 0.014	3.995LeuAsn: 3.995 ± 0.022	5.266LeuPro: 5.266 ± 0.026	4.397LeuGln: 4.397 ± 0.027	5.288LeuArg: 5.288 ± 0.026	8.547LeuSer: 8.547 ± 0.043	4.433LeuThr: 4.433 ± 0.028	6.071LeuVal: 6.071 ± 0.028	1.126LeuTrp: 1.126 ± 0.012	2.532LeuTyr: 2.532 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.206MetAla: 2.206 ± 0.015	0.382MetCys: 0.382 ± 0.006	1.434MetAsp: 1.434 ± 0.014	2.162MetGlu: 2.162 ± 0.015	0.76MetPhe: 0.76 ± 0.009	1.605MetGly: 1.605 ± 0.014	0.532MetHis: 0.532 ± 0.007	1.239MetIle: 1.239 ± 0.013	1.615MetLys: 1.615 ± 0.013	2.109MetLeu: 2.109 ± 0.016	0.659MetMet: 0.659 ± 0.008	0.995MetAsn: 0.995 ± 0.01	1.089MetPro: 1.089 ± 0.01	0.986MetGln: 0.986 ± 0.01	1.274MetArg: 1.274 ± 0.013	1.726MetSer: 1.726 ± 0.013	1.066MetThr: 1.066 ± 0.011	1.604MetVal: 1.604 ± 0.014	0.247MetTrp: 0.247 ± 0.005	0.582MetTyr: 0.582 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.657AsnAla: 2.657 ± 0.017	0.898AsnCys: 0.898 ± 0.01	2.194AsnAsp: 2.194 ± 0.016	2.623AsnGlu: 2.623 ± 0.019	2.031AsnPhe: 2.031 ± 0.016	3.372AsnGly: 3.372 ± 0.02	1.071AsnHis: 1.071 ± 0.011	2.489AsnIle: 2.489 ± 0.018	2.431AsnLys: 2.431 ± 0.017	4.733AsnLeu: 4.733 ± 0.035	1.092AsnMet: 1.092 ± 0.01	2.454AsnAsn: 2.454 ± 0.023	2.447AsnPro: 2.447 ± 0.016	1.821AsnGln: 1.821 ± 0.015	2.075AsnArg: 2.075 ± 0.015	3.981AsnSer: 3.981 ± 0.024	2.052AsnThr: 2.052 ± 0.026	2.73AsnVal: 2.73 ± 0.017	0.599AsnTrp: 0.599 ± 0.009	1.395AsnTyr: 1.395 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	3.314ProAla: 3.314 ± 0.022	0.732ProCys: 0.732 ± 0.008	2.534ProAsp: 2.534 ± 0.02	3.27ProGlu: 3.27 ± 0.018	2.076ProPhe: 2.076 ± 0.017	2.758ProGly: 2.758 ± 0.02	1.058ProHis: 1.058 ± 0.013	2.442ProIle: 2.442 ± 0.018	2.696ProLys: 2.696 ± 0.018	4.444ProLeu: 4.444 ± 0.023	1.025ProMet: 1.025 ± 0.01	2.323ProAsn: 2.323 ± 0.016	4.21ProPro: 4.21 ± 0.058	1.778ProGln: 1.778 ± 0.014	2.388ProArg: 2.388 ± 0.017	5.229ProSer: 5.229 ± 0.033	2.699ProThr: 2.699 ± 0.019	3.221ProVal: 3.221 ± 0.021	0.607ProTrp: 0.607 ± 0.009	1.368ProTyr: 1.368 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.455GlnAla: 2.455 ± 0.017	0.556GlnCys: 0.556 ± 0.007	1.664GlnAsp: 1.664 ± 0.015	2.567GlnGlu: 2.567 ± 0.019	1.397GlnPhe: 1.397 ± 0.013	2.158GlnGly: 2.158 ± 0.031	0.844GlnHis: 0.844 ± 0.01	2.053GlnIle: 2.053 ± 0.014	2.323GlnLys: 2.323 ± 0.018	3.804GlnLeu: 3.804 ± 0.019	1.004GlnMet: 1.004 ± 0.011	1.888GlnAsn: 1.888 ± 0.014	1.779GlnPro: 1.779 ± 0.018	2.065GlnGln: 2.065 ± 0.031	2.144GlnArg: 2.144 ± 0.018	2.921GlnSer: 2.921 ± 0.021	1.74GlnThr: 1.74 ± 0.015	2.367GlnVal: 2.367 ± 0.015	0.457GlnTrp: 0.457 ± 0.007	0.965GlnTyr: 0.965 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	3.33ArgAla: 3.33 ± 0.024	0.916ArgCys: 0.916 ± 0.01	2.587ArgAsp: 2.587 ± 0.018	3.383ArgGlu: 3.383 ± 0.021	2.253ArgPhe: 2.253 ± 0.017	3.194ArgGly: 3.194 ± 0.024	1.312ArgHis: 1.312 ± 0.014	3.022ArgIle: 3.022 ± 0.019	3.777ArgLys: 3.777 ± 0.023	5.157ArgLeu: 5.157 ± 0.026	1.422ArgMet: 1.422 ± 0.011	2.489ArgAsn: 2.489 ± 0.015	2.397ArgPro: 2.397 ± 0.019	1.928ArgGln: 1.928 ± 0.015	4.046ArgArg: 4.046 ± 0.03	4.329ArgSer: 4.329 ± 0.028	2.534ArgThr: 2.534 ± 0.016	3.244ArgVal: 3.244 ± 0.021	0.822ArgTrp: 0.822 ± 0.011	1.598ArgTyr: 1.598 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	5.237SerAla: 5.237 ± 0.025	1.679SerCys: 1.679 ± 0.014	4.317SerAsp: 4.317 ± 0.022	4.652SerGlu: 4.652 ± 0.026	3.977SerPhe: 3.977 ± 0.024	5.829SerGly: 5.829 ± 0.03	1.945SerHis: 1.945 ± 0.015	4.709SerIle: 4.709 ± 0.025	4.937SerLys: 4.937 ± 0.026	8.61SerLeu: 8.61 ± 0.035	2.052SerMet: 2.052 ± 0.016	4.21SerAsn: 4.21 ± 0.024	4.529SerPro: 4.529 ± 0.038	3.043SerGln: 3.043 ± 0.019	4.62SerArg: 4.62 ± 0.027	10.862SerSer: 10.862 ± 0.062	4.627SerThr: 4.627 ± 0.026	4.95SerVal: 4.95 ± 0.025	1.206SerTrp: 1.206 ± 0.013	2.345SerTyr: 2.345 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	3.522ThrAla: 3.522 ± 0.021	0.91ThrCys: 0.91 ± 0.01	2.303ThrAsp: 2.303 ± 0.016	2.858ThrGlu: 2.858 ± 0.019	2.005ThrPhe: 2.005 ± 0.016	3.342ThrGly: 3.342 ± 0.021	1.104ThrHis: 1.104 ± 0.011	2.8ThrIle: 2.8 ± 0.018	2.553ThrLys: 2.553 ± 0.017	4.532ThrLeu: 4.532 ± 0.022	1.128ThrMet: 1.128 ± 0.011	2.074ThrAsn: 2.074 ± 0.016	2.749ThrPro: 2.749 ± 0.017	1.683ThrGln: 1.683 ± 0.025	2.528ThrArg: 2.528 ± 0.017	4.569ThrSer: 4.569 ± 0.025	2.895ThrThr: 2.895 ± 0.023	3.391ThrVal: 3.391 ± 0.024	0.644ThrTrp: 0.644 ± 0.008	1.458ThrTyr: 1.458 ± 0.016	0.0ThrXaa: 0.0 ± 0.0
Val	4.66ValAla: 4.66 ± 0.024	1.023ValCys: 1.023 ± 0.012	3.6ValAsp: 3.6 ± 0.018	4.257ValGlu: 4.257 ± 0.025	2.614ValPhe: 2.614 ± 0.015	3.968ValGly: 3.968 ± 0.027	1.426ValHis: 1.426 ± 0.013	3.424ValIle: 3.424 ± 0.022	3.793ValLys: 3.793 ± 0.024	6.089ValLeu: 6.089 ± 0.027	1.472ValMet: 1.472 ± 0.014	2.616ValAsn: 2.616 ± 0.015	3.229ValPro: 3.229 ± 0.018	2.253ValGln: 2.253 ± 0.015	2.999ValArg: 2.999 ± 0.016	5.207ValSer: 5.207 ± 0.027	3.183ValThr: 3.183 ± 0.02	4.479ValVal: 4.479 ± 0.024	0.786ValTrp: 0.786 ± 0.009	1.879ValTyr: 1.879 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	0.86TrpAla: 0.86 ± 0.01	0.227TrpCys: 0.227 ± 0.005	0.708TrpAsp: 0.708 ± 0.009	0.763TrpGlu: 0.763 ± 0.009	0.548TrpPhe: 0.548 ± 0.008	0.736TrpGly: 0.736 ± 0.014	0.284TrpHis: 0.284 ± 0.006	0.726TrpIle: 0.726 ± 0.01	0.917TrpLys: 0.917 ± 0.009	1.253TrpLeu: 1.253 ± 0.013	0.327TrpMet: 0.327 ± 0.005	0.71TrpAsn: 0.71 ± 0.011	0.492TrpPro: 0.492 ± 0.007	0.484TrpGln: 0.484 ± 0.008	0.946TrpArg: 0.946 ± 0.011	0.943TrpSer: 0.943 ± 0.011	0.686TrpThr: 0.686 ± 0.009	0.816TrpVal: 0.816 ± 0.01	0.26TrpTrp: 0.26 ± 0.006	0.366TrpTyr: 0.366 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.899TyrAla: 1.899 ± 0.018	0.632TyrCys: 0.632 ± 0.008	1.548TyrAsp: 1.548 ± 0.013	1.661TyrGlu: 1.661 ± 0.015	1.357TyrPhe: 1.357 ± 0.012	2.176TyrGly: 2.176 ± 0.018	0.713TyrHis: 0.713 ± 0.01	1.481TyrIle: 1.481 ± 0.014	1.564TyrLys: 1.564 ± 0.015	2.783TyrLeu: 2.783 ± 0.018	0.709TyrMet: 0.709 ± 0.009	1.338TyrAsn: 1.338 ± 0.013	1.287TyrPro: 1.287 ± 0.012	1.001TyrGln: 1.001 ± 0.01	1.524TyrArg: 1.524 ± 0.013	2.293TyrSer: 2.293 ± 0.016	1.396TyrThr: 1.396 ± 0.015	1.711TyrVal: 1.711 ± 0.014	0.452TyrTrp: 0.452 ± 0.007	1.008TyrTyr: 1.008 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 27058 proteins (9912802 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---