Amino acid dipepetide frequency for Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.13AlaAla: 22.13 ± 0.168	1.912AlaCys: 1.912 ± 0.034	6.453AlaAsp: 6.453 ± 0.044	8.517AlaGlu: 8.517 ± 0.065	3.969AlaPhe: 3.969 ± 0.035	12.772AlaGly: 12.772 ± 0.077	2.646AlaHis: 2.646 ± 0.029	4.989AlaIle: 4.989 ± 0.037	2.928AlaLys: 2.928 ± 0.041	16.079AlaLeu: 16.079 ± 0.121	2.524AlaMet: 2.524 ± 0.026	1.883AlaAsn: 1.883 ± 0.024	9.732AlaPro: 9.732 ± 0.087	3.84AlaGln: 3.84 ± 0.038	13.229AlaArg: 13.229 ± 0.099	8.375AlaSer: 8.375 ± 0.055	6.283AlaThr: 6.283 ± 0.053	9.148AlaVal: 9.148 ± 0.059	1.876AlaTrp: 1.876 ± 0.028	2.33AlaTyr: 2.33 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	1.715CysAla: 1.715 ± 0.028	0.169CysCys: 0.169 ± 0.008	0.851CysAsp: 0.851 ± 0.029	0.719CysGlu: 0.719 ± 0.019	0.344CysPhe: 0.344 ± 0.01	1.334CysGly: 1.334 ± 0.032	0.268CysHis: 0.268 ± 0.01	0.344CysIle: 0.344 ± 0.01	0.255CysLys: 0.255 ± 0.009	0.886CysLeu: 0.886 ± 0.017	0.178CysMet: 0.178 ± 0.007	0.28CysAsn: 0.28 ± 0.013	0.716CysPro: 0.716 ± 0.02	0.297CysGln: 0.297 ± 0.01	0.818CysArg: 0.818 ± 0.018	0.819CysSer: 0.819 ± 0.022	0.606CysThr: 0.606 ± 0.019	0.875CysVal: 0.875 ± 0.019	0.154CysTrp: 0.154 ± 0.009	0.222CysTyr: 0.222 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	8.262AspAla: 8.262 ± 0.052	0.582AspCys: 0.582 ± 0.02	3.614AspAsp: 3.614 ± 0.042	4.023AspGlu: 4.023 ± 0.038	1.696AspPhe: 1.696 ± 0.022	6.227AspGly: 6.227 ± 0.073	1.128AspHis: 1.128 ± 0.018	1.837AspIle: 1.837 ± 0.024	1.14AspLys: 1.14 ± 0.019	5.908AspLeu: 5.908 ± 0.046	0.741AspMet: 0.741 ± 0.014	0.904AspAsn: 0.904 ± 0.023	4.307AspPro: 4.307 ± 0.04	1.304AspGln: 1.304 ± 0.02	4.586AspArg: 4.586 ± 0.034	1.933AspSer: 1.933 ± 0.026	2.129AspThr: 2.129 ± 0.028	4.738AspVal: 4.738 ± 0.041	0.663AspTrp: 0.663 ± 0.015	1.013AspTyr: 1.013 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	8.894GluAla: 8.894 ± 0.071	0.565GluCys: 0.565 ± 0.015	2.936GluAsp: 2.936 ± 0.031	3.762GluGlu: 3.762 ± 0.036	1.286GluPhe: 1.286 ± 0.02	5.289GluGly: 5.289 ± 0.039	1.526GluHis: 1.526 ± 0.024	2.877GluIle: 2.877 ± 0.03	1.537GluLys: 1.537 ± 0.025	7.233GluLeu: 7.233 ± 0.055	1.037GluMet: 1.037 ± 0.018	1.003GluAsn: 1.003 ± 0.018	3.803GluPro: 3.803 ± 0.041	2.36GluGln: 2.36 ± 0.026	7.077GluArg: 7.077 ± 0.059	2.712GluSer: 2.712 ± 0.031	2.466GluThr: 2.466 ± 0.03	4.516GluVal: 4.516 ± 0.039	0.578GluTrp: 0.578 ± 0.012	0.912GluTyr: 0.912 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.742PheAla: 3.742 ± 0.037	0.391PheCys: 0.391 ± 0.011	2.243PheAsp: 2.243 ± 0.026	2.092PheGlu: 2.092 ± 0.028	1.12PhePhe: 1.12 ± 0.02	3.036PheGly: 3.036 ± 0.03	0.708PheHis: 0.708 ± 0.014	0.953PheIle: 0.953 ± 0.017	0.628PheLys: 0.628 ± 0.015	2.789PheLeu: 2.789 ± 0.033	0.49PheMet: 0.49 ± 0.011	0.63PheAsn: 0.63 ± 0.014	1.493PhePro: 1.493 ± 0.022	0.84PheGln: 0.84 ± 0.015	2.22PheArg: 2.22 ± 0.024	1.832PheSer: 1.832 ± 0.023	1.635PheThr: 1.635 ± 0.022	2.455PheVal: 2.455 ± 0.029	0.42PheTrp: 0.42 ± 0.013	0.698PheTyr: 0.698 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	13.843GlyAla: 13.843 ± 0.099	1.332GlyCys: 1.332 ± 0.029	5.518GlyAsp: 5.518 ± 0.06	6.015GlyGlu: 6.015 ± 0.044	2.756GlyPhe: 2.756 ± 0.032	10.413GlyGly: 10.413 ± 0.132	1.772GlyHis: 1.772 ± 0.028	3.274GlyIle: 3.274 ± 0.034	2.699GlyLys: 2.699 ± 0.031	7.731GlyLeu: 7.731 ± 0.05	1.764GlyMet: 1.764 ± 0.026	1.781GlyAsn: 1.781 ± 0.03	4.707GlyPro: 4.707 ± 0.052	2.607GlyGln: 2.607 ± 0.032	7.228GlyArg: 7.228 ± 0.048	5.56GlySer: 5.56 ± 0.06	4.653GlyThr: 4.653 ± 0.053	6.79GlyVal: 6.79 ± 0.053	1.241GlyTrp: 1.241 ± 0.021	1.936GlyTyr: 1.936 ± 0.029	0.0GlyXaa: 0.0 ± 0.0
His	2.786HisAla: 2.786 ± 0.033	0.236HisCys: 0.236 ± 0.01	1.225HisAsp: 1.225 ± 0.018	1.346HisGlu: 1.346 ± 0.02	0.656HisPhe: 0.656 ± 0.014	2.095HisGly: 2.095 ± 0.029	0.606HisHis: 0.606 ± 0.015	0.642HisIle: 0.642 ± 0.015	0.354HisLys: 0.354 ± 0.01	2.112HisLeu: 2.112 ± 0.029	0.274HisMet: 0.274 ± 0.008	0.349HisAsn: 0.349 ± 0.01	1.47HisPro: 1.47 ± 0.022	0.48HisGln: 0.48 ± 0.012	1.831HisArg: 1.831 ± 0.027	0.706HisSer: 0.706 ± 0.015	0.813HisThr: 0.813 ± 0.016	1.742HisVal: 1.742 ± 0.024	0.25HisTrp: 0.25 ± 0.01	0.464HisTyr: 0.464 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	5.572IleAla: 5.572 ± 0.041	0.368IleCys: 0.368 ± 0.011	2.882IleAsp: 2.882 ± 0.033	3.186IleGlu: 3.186 ± 0.034	0.979IlePhe: 0.979 ± 0.018	3.269IleGly: 3.269 ± 0.035	0.792IleHis: 0.792 ± 0.014	0.956IleIle: 0.956 ± 0.018	0.856IleLys: 0.856 ± 0.016	2.846IleLeu: 2.846 ± 0.029	0.407IleMet: 0.407 ± 0.013	0.702IleAsn: 0.702 ± 0.017	1.947IlePro: 1.947 ± 0.026	0.945IleGln: 0.945 ± 0.016	2.4IleArg: 2.4 ± 0.027	1.846IleSer: 1.846 ± 0.025	1.886IleThr: 1.886 ± 0.025	3.068IleVal: 3.068 ± 0.032	0.374IleTrp: 0.374 ± 0.013	0.733IleTyr: 0.733 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	2.861LysAla: 2.861 ± 0.037	0.178LysCys: 0.178 ± 0.009	1.296LysAsp: 1.296 ± 0.025	1.388LysGlu: 1.388 ± 0.021	0.543LysPhe: 0.543 ± 0.013	1.913LysGly: 1.913 ± 0.027	0.468LysHis: 0.468 ± 0.012	1.072LysIle: 1.072 ± 0.02	0.954LysLys: 0.954 ± 0.023	2.502LysLeu: 2.502 ± 0.027	0.456LysMet: 0.456 ± 0.013	0.569LysAsn: 0.569 ± 0.013	1.534LysPro: 1.534 ± 0.026	0.727LysGln: 0.727 ± 0.016	1.955LysArg: 1.955 ± 0.027	1.197LysSer: 1.197 ± 0.018	1.278LysThr: 1.278 ± 0.021	1.791LysVal: 1.791 ± 0.027	0.221LysTrp: 0.221 ± 0.008	0.437LysTyr: 0.437 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	14.693LeuAla: 14.693 ± 0.095	1.159LeuCys: 1.159 ± 0.017	6.582LeuAsp: 6.582 ± 0.054	5.986LeuGlu: 5.986 ± 0.058	3.115LeuPhe: 3.115 ± 0.031	9.406LeuGly: 9.406 ± 0.061	2.113LeuHis: 2.113 ± 0.025	3.021LeuIle: 3.021 ± 0.032	2.206LeuLys: 2.206 ± 0.03	10.487LeuLeu: 10.487 ± 0.081	1.387LeuMet: 1.387 ± 0.02	1.554LeuAsn: 1.554 ± 0.022	5.98LeuPro: 5.98 ± 0.046	2.328LeuGln: 2.328 ± 0.031	9.113LeuArg: 9.113 ± 0.06	6.447LeuSer: 6.447 ± 0.043	4.753LeuThr: 4.753 ± 0.037	7.907LeuVal: 7.907 ± 0.057	1.172LeuTrp: 1.172 ± 0.019	1.902LeuTyr: 1.902 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.098MetAla: 2.098 ± 0.023	0.162MetCys: 0.162 ± 0.007	0.809MetAsp: 0.809 ± 0.016	0.801MetGlu: 0.801 ± 0.014	0.455MetPhe: 0.455 ± 0.013	1.328MetGly: 1.328 ± 0.022	0.359MetHis: 0.359 ± 0.01	0.67MetIle: 0.67 ± 0.014	0.63MetLys: 0.63 ± 0.013	1.718MetLeu: 1.718 ± 0.024	0.349MetMet: 0.349 ± 0.012	0.5MetAsn: 0.5 ± 0.012	1.141MetPro: 1.141 ± 0.019	0.489MetGln: 0.489 ± 0.011	1.516MetArg: 1.516 ± 0.024	1.289MetSer: 1.289 ± 0.019	1.153MetThr: 1.153 ± 0.019	1.158MetVal: 1.158 ± 0.02	0.154MetTrp: 0.154 ± 0.007	0.244MetTyr: 0.244 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.229AsnAla: 2.229 ± 0.028	0.228AsnCys: 0.228 ± 0.013	1.075AsnAsp: 1.075 ± 0.023	0.969AsnGlu: 0.969 ± 0.017	0.536AsnPhe: 0.536 ± 0.014	1.8AsnGly: 1.8 ± 0.031	0.399AsnHis: 0.399 ± 0.011	0.701AsnIle: 0.701 ± 0.015	0.415AsnLys: 0.415 ± 0.012	1.778AsnLeu: 1.778 ± 0.025	0.271AsnMet: 0.271 ± 0.008	0.479AsnAsn: 0.479 ± 0.014	1.32AsnPro: 1.32 ± 0.022	0.528AsnGln: 0.528 ± 0.014	1.183AsnArg: 1.183 ± 0.018	0.734AsnSer: 0.734 ± 0.014	0.857AsnThr: 0.857 ± 0.021	1.504AsnVal: 1.504 ± 0.022	0.197AsnTrp: 0.197 ± 0.008	0.389AsnTyr: 0.389 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	9.35ProAla: 9.35 ± 0.08	0.596ProCys: 0.596 ± 0.016	3.696ProAsp: 3.696 ± 0.044	4.627ProGlu: 4.627 ± 0.04	1.932ProPhe: 1.932 ± 0.025	6.182ProGly: 6.182 ± 0.058	1.102ProHis: 1.102 ± 0.018	2.082ProIle: 2.082 ± 0.025	1.267ProLys: 1.267 ± 0.025	5.629ProLeu: 5.629 ± 0.044	1.145ProMet: 1.145 ± 0.018	1.056ProAsn: 1.056 ± 0.018	5.469ProPro: 5.469 ± 0.076	1.441ProGln: 1.441 ± 0.029	5.0ProArg: 5.0 ± 0.039	4.267ProSer: 4.267 ± 0.045	2.773ProThr: 2.773 ± 0.03	4.143ProVal: 4.143 ± 0.037	0.829ProTrp: 0.829 ± 0.015	1.106ProTyr: 1.106 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.576GlnAla: 3.576 ± 0.034	0.285GlnCys: 0.285 ± 0.012	1.165GlnAsp: 1.165 ± 0.02	1.39GlnGlu: 1.39 ± 0.022	0.689GlnPhe: 0.689 ± 0.016	2.396GlnGly: 2.396 ± 0.037	0.596GlnHis: 0.596 ± 0.013	1.298GlnIle: 1.298 ± 0.019	0.768GlnLys: 0.768 ± 0.016	2.765GlnLeu: 2.765 ± 0.028	0.509GlnMet: 0.509 ± 0.012	0.528GlnAsn: 0.528 ± 0.012	1.718GlnPro: 1.718 ± 0.028	0.993GlnGln: 0.993 ± 0.021	2.804GlnArg: 2.804 ± 0.026	1.322GlnSer: 1.322 ± 0.018	1.171GlnThr: 1.171 ± 0.019	2.003GlnVal: 2.003 ± 0.027	0.339GlnTrp: 0.339 ± 0.011	0.457GlnTyr: 0.457 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	12.618ArgAla: 12.618 ± 0.091	1.036ArgCys: 1.036 ± 0.021	4.65ArgAsp: 4.65 ± 0.036	5.388ArgGlu: 5.388 ± 0.05	3.155ArgPhe: 3.155 ± 0.032	6.919ArgGly: 6.919 ± 0.045	1.73ArgHis: 1.73 ± 0.025	3.386ArgIle: 3.386 ± 0.035	1.835ArgLys: 1.835 ± 0.026	9.037ArgLeu: 9.037 ± 0.067	1.725ArgMet: 1.725 ± 0.022	1.25ArgAsn: 1.25 ± 0.019	4.904ArgPro: 4.904 ± 0.044	2.112ArgGln: 2.112 ± 0.023	8.394ArgArg: 8.394 ± 0.059	4.825ArgSer: 4.825 ± 0.038	3.664ArgThr: 3.664 ± 0.041	6.316ArgVal: 6.316 ± 0.044	1.36ArgTrp: 1.36 ± 0.023	1.945ArgTyr: 1.945 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	7.828SerAla: 7.828 ± 0.056	0.754SerCys: 0.754 ± 0.019	2.971SerAsp: 2.971 ± 0.029	2.897SerGlu: 2.897 ± 0.029	2.018SerPhe: 2.018 ± 0.025	6.113SerGly: 6.113 ± 0.063	0.979SerHis: 0.979 ± 0.019	2.093SerIle: 2.093 ± 0.026	1.185SerLys: 1.185 ± 0.023	5.426SerLeu: 5.426 ± 0.038	1.044SerMet: 1.044 ± 0.017	1.016SerAsn: 1.016 ± 0.019	4.069SerPro: 4.069 ± 0.038	1.332SerGln: 1.332 ± 0.021	4.304SerArg: 4.304 ± 0.037	4.2SerSer: 4.2 ± 0.064	2.985SerThr: 2.985 ± 0.032	3.933SerVal: 3.933 ± 0.036	0.789SerTrp: 0.789 ± 0.013	1.134SerTyr: 1.134 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.837ThrAla: 5.837 ± 0.048	0.645ThrCys: 0.645 ± 0.02	2.314ThrAsp: 2.314 ± 0.03	2.366ThrGlu: 2.366 ± 0.024	1.672ThrPhe: 1.672 ± 0.024	4.803ThrGly: 4.803 ± 0.044	0.899ThrHis: 0.899 ± 0.016	1.847ThrIle: 1.847 ± 0.023	1.059ThrLys: 1.059 ± 0.019	5.042ThrLeu: 5.042 ± 0.036	0.866ThrMet: 0.866 ± 0.019	0.922ThrAsn: 0.922 ± 0.019	3.381ThrPro: 3.381 ± 0.038	1.197ThrGln: 1.197 ± 0.022	3.48ThrArg: 3.48 ± 0.033	3.12ThrSer: 3.12 ± 0.045	2.739ThrThr: 2.739 ± 0.035	3.558ThrVal: 3.558 ± 0.034	0.713ThrTrp: 0.713 ± 0.017	1.065ThrTyr: 1.065 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	9.971ValAla: 9.971 ± 0.062	0.877ValCys: 0.877 ± 0.022	4.557ValAsp: 4.557 ± 0.036	4.988ValGlu: 4.988 ± 0.044	2.326ValPhe: 2.326 ± 0.025	5.693ValGly: 5.693 ± 0.043	1.654ValHis: 1.654 ± 0.026	2.813ValIle: 2.813 ± 0.027	1.819ValLys: 1.819 ± 0.026	7.852ValLeu: 7.852 ± 0.06	1.228ValMet: 1.228 ± 0.02	1.392ValAsn: 1.392 ± 0.024	4.295ValPro: 4.295 ± 0.037	1.951ValGln: 1.951 ± 0.023	6.212ValArg: 6.212 ± 0.048	4.079ValSer: 4.079 ± 0.039	3.979ValThr: 3.979 ± 0.041	6.442ValVal: 6.442 ± 0.057	0.897ValTrp: 0.897 ± 0.018	1.463ValTyr: 1.463 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.324TrpAla: 1.324 ± 0.018	0.139TrpCys: 0.139 ± 0.007	0.667TrpAsp: 0.667 ± 0.015	0.691TrpGlu: 0.691 ± 0.013	0.416TrpPhe: 0.416 ± 0.011	0.936TrpGly: 0.936 ± 0.019	0.283TrpHis: 0.283 ± 0.01	0.596TrpIle: 0.596 ± 0.015	0.375TrpLys: 0.375 ± 0.011	1.5TrpLeu: 1.5 ± 0.022	0.299TrpMet: 0.299 ± 0.01	0.341TrpAsn: 0.341 ± 0.012	0.66TrpPro: 0.66 ± 0.011	0.419TrpGln: 0.419 ± 0.011	1.065TrpArg: 1.065 ± 0.017	0.931TrpSer: 0.931 ± 0.019	0.763TrpThr: 0.763 ± 0.016	0.863TrpVal: 0.863 ± 0.017	0.167TrpTrp: 0.167 ± 0.007	0.256TrpTyr: 0.256 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.284TyrAla: 2.284 ± 0.024	0.235TyrCys: 0.235 ± 0.009	1.231TyrAsp: 1.231 ± 0.022	1.216TyrGlu: 1.216 ± 0.019	0.752TyrPhe: 0.752 ± 0.013	1.694TyrGly: 1.694 ± 0.024	0.409TyrHis: 0.409 ± 0.012	0.564TyrIle: 0.564 ± 0.013	0.431TyrLys: 0.431 ± 0.011	1.988TyrLeu: 1.988 ± 0.023	0.331TyrMet: 0.331 ± 0.008	0.452TyrAsn: 0.452 ± 0.013	1.049TyrPro: 1.049 ± 0.021	0.584TyrGln: 0.584 ± 0.013	1.834TyrArg: 1.834 ± 0.025	0.874TyrSer: 0.874 ± 0.017	0.943TyrThr: 0.943 ± 0.018	1.536TyrVal: 1.536 ± 0.024	0.298TyrTrp: 0.298 ± 0.009	0.492TyrTyr: 0.492 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9320 proteins (3743060 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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