Amino acid dipepetide frequency for Cryphonectria nitschkei chrysovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.863AlaAla: 7.863 ± 1.072
1.165AlaCys: 1.165 ± 0.473
4.368AlaAsp: 4.368 ± 1.164
5.533AlaGlu: 5.533 ± 0.156
2.33AlaPhe: 2.33 ± 0.536
5.533AlaGly: 5.533 ± 0.788
2.038AlaHis: 2.038 ± 0.606
6.115AlaIle: 6.115 ± 0.572
2.33AlaLys: 2.33 ± 0.997
5.533AlaLeu: 5.533 ± 1.321
0.582AlaMet: 0.582 ± 0.314
3.203AlaAsn: 3.203 ± 0.602
2.621AlaPro: 2.621 ± 0.671
2.038AlaGln: 2.038 ± 0.947
5.533AlaArg: 5.533 ± 1.186
7.571AlaSer: 7.571 ± 1.188
6.115AlaThr: 6.115 ± 2.238
8.154AlaVal: 8.154 ± 0.792
1.456AlaTrp: 1.456 ± 0.438
2.038AlaTyr: 2.038 ± 0.311
0.0AlaXaa: 0.0 ± 0.0
Cys
1.456CysAla: 1.456 ± 0.21
0.0CysCys: 0.0 ± 0.0
0.582CysAsp: 0.582 ± 0.558
0.874CysGlu: 0.874 ± 0.466
0.291CysPhe: 0.291 ± 0.253
2.33CysGly: 2.33 ± 0.788
0.291CysHis: 0.291 ± 0.235
0.874CysIle: 0.874 ± 0.837
1.165CysLys: 1.165 ± 0.407
0.291CysLeu: 0.291 ± 0.235
0.291CysMet: 0.291 ± 0.253
0.0CysAsn: 0.0 ± 0.0
0.874CysPro: 0.874 ± 0.277
0.874CysGln: 0.874 ± 0.706
0.874CysArg: 0.874 ± 0.283
0.874CysSer: 0.874 ± 0.277
0.291CysThr: 0.291 ± 0.242
1.456CysVal: 1.456 ± 0.583
0.582CysTrp: 0.582 ± 0.47
0.291CysTyr: 0.291 ± 0.242
0.0CysXaa: 0.0 ± 0.0
Asp
2.912AspAla: 2.912 ± 0.428
1.165AspCys: 1.165 ± 0.473
4.368AspAsp: 4.368 ± 1.022
3.786AspGlu: 3.786 ± 0.186
3.203AspPhe: 3.203 ± 0.797
5.533AspGly: 5.533 ± 1.262
0.874AspHis: 0.874 ± 0.277
2.038AspIle: 2.038 ± 0.723
3.494AspLys: 3.494 ± 1.269
4.659AspLeu: 4.659 ± 0.522
1.747AspMet: 1.747 ± 0.464
1.165AspAsn: 1.165 ± 0.433
2.038AspPro: 2.038 ± 0.56
1.456AspGln: 1.456 ± 0.604
4.368AspArg: 4.368 ± 0.293
4.659AspSer: 4.659 ± 0.758
2.621AspThr: 2.621 ± 0.775
5.533AspVal: 5.533 ± 0.714
2.33AspTrp: 2.33 ± 0.741
3.494AspTyr: 3.494 ± 1.17
0.0AspXaa: 0.0 ± 0.0
Glu
5.533GluAla: 5.533 ± 1.195
1.456GluCys: 1.456 ± 0.522
4.077GluAsp: 4.077 ± 1.124
4.368GluGlu: 4.368 ± 0.356
1.456GluPhe: 1.456 ± 0.573
2.912GluGly: 2.912 ± 1.015
2.038GluHis: 2.038 ± 0.417
2.038GluIle: 2.038 ± 0.191
2.33GluLys: 2.33 ± 0.536
7.863GluLeu: 7.863 ± 0.944
2.912GluMet: 2.912 ± 0.876
0.582GluAsn: 0.582 ± 0.506
2.038GluPro: 2.038 ± 0.418
3.203GluGln: 3.203 ± 0.483
6.115GluArg: 6.115 ± 0.61
4.368GluSer: 4.368 ± 0.284
2.33GluThr: 2.33 ± 0.646
4.95GluVal: 4.95 ± 0.333
1.747GluTrp: 1.747 ± 0.76
1.456GluTyr: 1.456 ± 0.638
0.0GluXaa: 0.0 ± 0.0
Phe
2.621PheAla: 2.621 ± 0.819
0.582PheCys: 0.582 ± 0.485
2.038PheAsp: 2.038 ± 0.418
3.203PheGlu: 3.203 ± 0.991
0.582PhePhe: 0.582 ± 0.264
2.912PheGly: 2.912 ± 0.96
1.165PheHis: 1.165 ± 0.407
1.456PheIle: 1.456 ± 0.89
0.291PheLys: 0.291 ± 0.253
0.874PheLeu: 0.874 ± 0.44
0.582PheMet: 0.582 ± 0.263
2.038PheAsn: 2.038 ± 0.388
0.874PhePro: 0.874 ± 0.447
0.0PheGln: 0.0 ± 0.0
0.582PheArg: 0.582 ± 0.485
2.33PheSer: 2.33 ± 0.371
1.456PheThr: 1.456 ± 0.426
1.456PheVal: 1.456 ± 0.21
0.0PheTrp: 0.0 ± 0.0
0.874PheTyr: 0.874 ± 0.277
0.0PheXaa: 0.0 ± 0.0
Gly
4.368GlyAla: 4.368 ± 0.912
1.165GlyCys: 1.165 ± 0.435
3.786GlyAsp: 3.786 ± 0.967
4.95GlyGlu: 4.95 ± 0.794
1.456GlyPhe: 1.456 ± 0.406
7.863GlyGly: 7.863 ± 1.685
3.203GlyHis: 3.203 ± 0.867
3.786GlyIle: 3.786 ± 0.684
4.659GlyLys: 4.659 ± 1.405
9.319GlyLeu: 9.319 ± 1.296
2.912GlyMet: 2.912 ± 1.342
1.165GlyAsn: 1.165 ± 0.058
1.747GlyPro: 1.747 ± 0.488
1.165GlyGln: 1.165 ± 0.433
5.824GlyArg: 5.824 ± 1.532
5.533GlySer: 5.533 ± 0.442
3.203GlyThr: 3.203 ± 0.729
4.659GlyVal: 4.659 ± 1.331
2.038GlyTrp: 2.038 ± 0.555
2.621GlyTyr: 2.621 ± 0.631
0.0GlyXaa: 0.0 ± 0.0
His
2.038HisAla: 2.038 ± 0.614
0.291HisCys: 0.291 ± 0.235
1.747HisAsp: 1.747 ± 0.562
3.203HisGlu: 3.203 ± 0.573
0.291HisPhe: 0.291 ± 0.242
2.038HisGly: 2.038 ± 0.872
0.582HisHis: 0.582 ± 0.263
0.874HisIle: 0.874 ± 0.436
1.456HisLys: 1.456 ± 1.074
1.165HisLeu: 1.165 ± 0.364
1.747HisMet: 1.747 ± 0.248
1.165HisAsn: 1.165 ± 0.67
0.874HisPro: 0.874 ± 0.283
0.874HisGln: 0.874 ± 0.283
0.582HisArg: 0.582 ± 0.318
1.456HisSer: 1.456 ± 0.546
0.582HisThr: 0.582 ± 0.485
2.038HisVal: 2.038 ± 0.691
0.291HisTrp: 0.291 ± 0.242
0.874HisTyr: 0.874 ± 0.232
0.0HisXaa: 0.0 ± 0.0
Ile
3.494IleAla: 3.494 ± 0.722
0.291IleCys: 0.291 ± 0.242
2.621IleAsp: 2.621 ± 0.845
2.33IleGlu: 2.33 ± 1.177
1.165IlePhe: 1.165 ± 0.67
4.368IleGly: 4.368 ± 1.139
1.165IleHis: 1.165 ± 0.659
2.33IleIle: 2.33 ± 1.031
3.203IleLys: 3.203 ± 1.053
3.494IleLeu: 3.494 ± 0.582
0.582IleMet: 0.582 ± 0.314
2.33IleAsn: 2.33 ± 0.355
2.912IlePro: 2.912 ± 0.697
0.0IleGln: 0.0 ± 0.0
2.912IleArg: 2.912 ± 0.92
3.494IleSer: 3.494 ± 0.507
3.786IleThr: 3.786 ± 0.834
2.621IleVal: 2.621 ± 0.974
0.874IleTrp: 0.874 ± 0.277
2.038IleTyr: 2.038 ± 0.478
0.0IleXaa: 0.0 ± 0.0
Lys
4.95LysAla: 4.95 ± 2.301
1.456LysCys: 1.456 ± 1.176
3.786LysAsp: 3.786 ± 0.943
4.077LysGlu: 4.077 ± 1.411
2.038LysPhe: 2.038 ± 0.814
2.912LysGly: 2.912 ± 0.48
0.874LysHis: 0.874 ± 0.509
2.038LysIle: 2.038 ± 0.56
1.456LysLys: 1.456 ± 0.21
4.077LysLeu: 4.077 ± 0.526
3.203LysMet: 3.203 ± 0.867
0.874LysAsn: 0.874 ± 0.436
1.456LysPro: 1.456 ± 0.21
1.456LysGln: 1.456 ± 0.931
4.659LysArg: 4.659 ± 1.209
2.33LysSer: 2.33 ± 1.063
3.203LysThr: 3.203 ± 1.17
4.659LysVal: 4.659 ± 1.168
0.291LysTrp: 0.291 ± 0.242
0.291LysTyr: 0.291 ± 0.253
0.0LysXaa: 0.0 ± 0.0
Leu
9.027LeuAla: 9.027 ± 1.579
1.165LeuCys: 1.165 ± 0.37
4.368LeuAsp: 4.368 ± 0.784
4.077LeuGlu: 4.077 ± 0.836
2.912LeuPhe: 2.912 ± 1.765
6.407LeuGly: 6.407 ± 1.717
2.038LeuHis: 2.038 ± 0.418
3.786LeuIle: 3.786 ± 1.265
3.786LeuLys: 3.786 ± 1.008
8.736LeuLeu: 8.736 ± 2.075
4.368LeuMet: 4.368 ± 0.417
2.33LeuAsn: 2.33 ± 0.611
3.494LeuPro: 3.494 ± 0.596
2.912LeuGln: 2.912 ± 0.48
4.077LeuArg: 4.077 ± 1.351
8.154LeuSer: 8.154 ± 1.408
7.571LeuThr: 7.571 ± 0.837
6.989LeuVal: 6.989 ± 1.285
2.038LeuTrp: 2.038 ± 0.529
2.038LeuTyr: 2.038 ± 0.783
0.0LeuXaa: 0.0 ± 0.0
Met
4.077MetAla: 4.077 ± 0.553
0.0MetCys: 0.0 ± 0.0
2.33MetAsp: 2.33 ± 0.821
1.456MetGlu: 1.456 ± 0.24
0.582MetPhe: 0.582 ± 0.263
1.747MetGly: 1.747 ± 0.566
0.582MetHis: 0.582 ± 0.506
0.874MetIle: 0.874 ± 0.457
0.874MetLys: 0.874 ± 0.436
3.203MetLeu: 3.203 ± 1.141
2.038MetMet: 2.038 ± 0.555
1.456MetAsn: 1.456 ± 0.573
2.038MetPro: 2.038 ± 0.388
0.874MetGln: 0.874 ± 0.508
3.786MetArg: 3.786 ± 0.488
4.368MetSer: 4.368 ± 0.147
1.165MetThr: 1.165 ± 0.473
2.038MetVal: 2.038 ± 0.614
0.874MetTrp: 0.874 ± 0.55
1.747MetTyr: 1.747 ± 0.616
0.0MetXaa: 0.0 ± 0.0
Asn
2.621AsnAla: 2.621 ± 0.524
0.291AsnCys: 0.291 ± 0.279
0.582AsnAsp: 0.582 ± 0.305
1.747AsnGlu: 1.747 ± 0.842
0.291AsnPhe: 0.291 ± 0.242
2.038AsnGly: 2.038 ± 0.614
0.582AsnHis: 0.582 ± 0.263
2.621AsnIle: 2.621 ± 0.604
1.165AsnLys: 1.165 ± 0.629
3.203AsnLeu: 3.203 ± 0.906
1.165AsnMet: 1.165 ± 0.659
0.874AsnAsn: 0.874 ± 0.232
0.582AsnPro: 0.582 ± 0.506
1.165AsnGln: 1.165 ± 0.435
3.203AsnArg: 3.203 ± 0.545
2.33AsnSer: 2.33 ± 0.728
1.165AsnThr: 1.165 ± 0.659
2.912AsnVal: 2.912 ± 1.276
0.291AsnTrp: 0.291 ± 0.235
0.874AsnTyr: 0.874 ± 0.508
0.0AsnXaa: 0.0 ± 0.0
Pro
3.203ProAla: 3.203 ± 1.069
0.291ProCys: 0.291 ± 0.242
2.621ProAsp: 2.621 ± 0.757
2.621ProGlu: 2.621 ± 0.593
0.874ProPhe: 0.874 ± 0.283
2.912ProGly: 2.912 ± 0.912
0.582ProHis: 0.582 ± 0.485
1.456ProIle: 1.456 ± 0.772
3.203ProLys: 3.203 ± 0.497
1.456ProLeu: 1.456 ± 0.24
0.291ProMet: 0.291 ± 0.253
1.456ProAsn: 1.456 ± 0.931
2.038ProPro: 2.038 ± 0.939
1.165ProGln: 1.165 ± 0.408
2.912ProArg: 2.912 ± 0.93
3.786ProSer: 3.786 ± 0.947
2.621ProThr: 2.621 ± 0.241
3.203ProVal: 3.203 ± 0.867
0.291ProTrp: 0.291 ± 0.242
0.874ProTyr: 0.874 ± 0.232
0.0ProXaa: 0.0 ± 0.0
Gln
2.33GlnAla: 2.33 ± 1.042
0.291GlnCys: 0.291 ± 0.235
1.456GlnAsp: 1.456 ± 0.33
1.165GlnGlu: 1.165 ± 0.385
0.874GlnPhe: 0.874 ± 0.227
1.747GlnGly: 1.747 ± 0.702
0.874GlnHis: 0.874 ± 0.447
1.165GlnIle: 1.165 ± 0.69
0.874GlnLys: 0.874 ± 0.759
5.242GlnLeu: 5.242 ± 0.279
0.582GlnMet: 0.582 ± 0.305
0.874GlnAsn: 0.874 ± 0.466
1.165GlnPro: 1.165 ± 0.385
1.165GlnGln: 1.165 ± 0.812
1.165GlnArg: 1.165 ± 0.812
2.912GlnSer: 2.912 ± 0.421
0.874GlnThr: 0.874 ± 0.484
2.912GlnVal: 2.912 ± 0.318
0.0GlnTrp: 0.0 ± 0.0
1.165GlnTyr: 1.165 ± 0.058
0.0GlnXaa: 0.0 ± 0.0
Arg
5.824ArgAla: 5.824 ± 0.695
0.0ArgCys: 0.0 ± 0.0
4.368ArgAsp: 4.368 ± 1.357
6.115ArgGlu: 6.115 ± 0.498
0.582ArgPhe: 0.582 ± 0.485
5.824ArgGly: 5.824 ± 0.707
2.621ArgHis: 2.621 ± 0.665
2.621ArgIle: 2.621 ± 0.735
3.203ArgLys: 3.203 ± 1.321
6.407ArgLeu: 6.407 ± 1.102
2.33ArgMet: 2.33 ± 0.957
1.165ArgAsn: 1.165 ± 0.435
2.621ArgPro: 2.621 ± 1.142
2.621ArgGln: 2.621 ± 0.819
4.95ArgArg: 4.95 ± 1.127
4.659ArgSer: 4.659 ± 1.069
4.659ArgThr: 4.659 ± 0.325
4.95ArgVal: 4.95 ± 0.984
1.165ArgTrp: 1.165 ± 0.364
2.33ArgTyr: 2.33 ± 0.355
0.0ArgXaa: 0.0 ± 0.0
Ser
7.863SerAla: 7.863 ± 0.553
1.456SerCys: 1.456 ± 0.695
4.368SerAsp: 4.368 ± 1.718
3.203SerGlu: 3.203 ± 0.885
2.33SerPhe: 2.33 ± 0.856
5.533SerGly: 5.533 ± 1.002
1.165SerHis: 1.165 ± 0.385
4.368SerIle: 4.368 ± 1.306
5.242SerLys: 5.242 ± 1.107
9.901SerLeu: 9.901 ± 0.664
3.203SerMet: 3.203 ± 1.05
2.912SerAsn: 2.912 ± 0.761
3.494SerPro: 3.494 ± 0.174
3.786SerGln: 3.786 ± 0.927
4.95SerArg: 4.95 ± 0.949
5.533SerSer: 5.533 ± 1.089
2.912SerThr: 2.912 ± 1.012
5.533SerVal: 5.533 ± 1.082
1.456SerTrp: 1.456 ± 0.583
2.912SerTyr: 2.912 ± 0.522
0.0SerXaa: 0.0 ± 0.0
Thr
2.038ThrAla: 2.038 ± 0.552
0.874ThrCys: 0.874 ± 0.482
3.494ThrAsp: 3.494 ± 1.679
2.33ThrGlu: 2.33 ± 1.067
2.038ThrPhe: 2.038 ± 0.606
3.494ThrGly: 3.494 ± 0.481
1.456ThrHis: 1.456 ± 0.702
1.165ThrIle: 1.165 ± 0.433
4.659ThrLys: 4.659 ± 0.75
4.368ThrLeu: 4.368 ± 1.154
2.621ThrMet: 2.621 ± 0.458
0.874ThrAsn: 0.874 ± 0.232
2.038ThrPro: 2.038 ± 0.418
1.165ThrGln: 1.165 ± 0.433
4.368ThrArg: 4.368 ± 0.988
7.571ThrSer: 7.571 ± 0.972
3.786ThrThr: 3.786 ± 0.518
4.077ThrVal: 4.077 ± 0.956
1.165ThrTrp: 1.165 ± 0.629
2.038ThrTyr: 2.038 ± 0.788
0.0ThrXaa: 0.0 ± 0.0
Val
4.659ValAla: 4.659 ± 0.604
1.747ValCys: 1.747 ± 0.306
6.115ValAsp: 6.115 ± 1.557
4.95ValGlu: 4.95 ± 1.512
1.165ValPhe: 1.165 ± 0.364
6.115ValGly: 6.115 ± 0.973
0.874ValHis: 0.874 ± 0.232
3.786ValIle: 3.786 ± 0.778
4.077ValLys: 4.077 ± 1.26
6.407ValLeu: 6.407 ± 0.722
2.621ValMet: 2.621 ± 0.927
3.786ValAsn: 3.786 ± 1.549
3.494ValPro: 3.494 ± 0.666
2.038ValGln: 2.038 ± 0.656
6.115ValArg: 6.115 ± 0.672
6.698ValSer: 6.698 ± 1.5
4.95ValThr: 4.95 ± 0.915
6.698ValVal: 6.698 ± 0.98
0.874ValTrp: 0.874 ± 0.232
1.165ValTyr: 1.165 ± 0.659
0.0ValXaa: 0.0 ± 0.0
Trp
2.038TrpAla: 2.038 ± 0.951
0.874TrpCys: 0.874 ± 0.277
0.874TrpAsp: 0.874 ± 0.436
1.747TrpGlu: 1.747 ± 0.306
0.291TrpPhe: 0.291 ± 0.242
0.874TrpGly: 0.874 ± 0.436
0.291TrpHis: 0.291 ± 0.235
0.582TrpIle: 0.582 ± 0.263
1.165TrpLys: 1.165 ± 0.702
2.621TrpLeu: 2.621 ± 0.735
0.582TrpMet: 0.582 ± 0.263
0.0TrpAsn: 0.0 ± 0.0
0.582TrpPro: 0.582 ± 0.264
0.582TrpGln: 0.582 ± 0.289
1.165TrpArg: 1.165 ± 0.629
1.456TrpSer: 1.456 ± 0.24
0.0TrpThr: 0.0 ± 0.0
1.165TrpVal: 1.165 ± 0.659
0.291TrpTrp: 0.291 ± 0.253
0.874TrpTyr: 0.874 ± 0.277
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.203TyrAla: 3.203 ± 0.605
0.0TyrCys: 0.0 ± 0.0
3.494TyrAsp: 3.494 ± 1.251
2.038TyrGlu: 2.038 ± 0.66
1.165TyrPhe: 1.165 ± 0.433
2.33TyrGly: 2.33 ± 0.608
0.874TyrHis: 0.874 ± 0.487
2.038TyrIle: 2.038 ± 0.418
1.456TyrLys: 1.456 ± 0.545
1.747TyrLeu: 1.747 ± 0.867
1.456TyrMet: 1.456 ± 0.604
1.456TyrAsn: 1.456 ± 0.438
0.874TyrPro: 0.874 ± 0.482
0.291TyrGln: 0.291 ± 0.253
0.874TyrArg: 0.874 ± 0.232
2.038TyrSer: 2.038 ± 0.417
2.33TyrThr: 2.33 ± 0.997
2.33TyrVal: 2.33 ± 0.819
0.0TyrTrp: 0.0 ± 0.0
0.582TyrTyr: 0.582 ± 0.485
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3435 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski