Amino acid dipepetide frequency for Beihai noda-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.505AlaAla: 4.505 ± 0.641
0.751AlaCys: 0.751 ± 0.375
1.502AlaAsp: 1.502 ± 0.75
2.252AlaGlu: 2.252 ± 1.124
3.003AlaPhe: 3.003 ± 0.109
6.757AlaGly: 6.757 ± 3.058
3.003AlaHis: 3.003 ± 0.109
3.754AlaIle: 3.754 ± 0.266
5.255AlaLys: 5.255 ± 1.016
0.0AlaLeu: 0.0 ± 0.0
1.502AlaMet: 1.502 ± 0.75
6.006AlaAsn: 6.006 ± 1.391
3.003AlaPro: 3.003 ± 0.109
1.502AlaGln: 1.502 ± 0.858
8.258AlaArg: 8.258 ± 0.907
9.76AlaSer: 9.76 ± 1.657
6.757AlaThr: 6.757 ± 0.158
8.258AlaVal: 8.258 ± 2.309
0.751AlaTrp: 0.751 ± 0.375
3.003AlaTyr: 3.003 ± 0.109
0.0AlaXaa: 0.0 ± 0.0
Cys
0.751CysAla: 0.751 ± 0.375
0.0CysCys: 0.0 ± 0.0
1.502CysAsp: 1.502 ± 0.75
0.751CysGlu: 0.751 ± 1.233
0.0CysPhe: 0.0 ± 0.0
0.751CysGly: 0.751 ± 0.375
0.751CysHis: 0.751 ± 0.375
0.0CysIle: 0.0 ± 0.0
0.751CysLys: 0.751 ± 0.375
1.502CysLeu: 1.502 ± 0.75
0.0CysMet: 0.0 ± 0.0
1.502CysAsn: 1.502 ± 0.75
1.502CysPro: 1.502 ± 0.858
0.0CysGln: 0.0 ± 0.0
0.751CysArg: 0.751 ± 0.375
0.751CysSer: 0.751 ± 0.375
1.502CysThr: 1.502 ± 0.75
0.751CysVal: 0.751 ± 1.233
0.0CysTrp: 0.0 ± 0.0
2.252CysTyr: 2.252 ± 0.483
0.0CysXaa: 0.0 ± 0.0
Asp
4.505AspAla: 4.505 ± 0.967
0.751AspCys: 0.751 ± 0.375
3.003AspAsp: 3.003 ± 1.499
2.252AspGlu: 2.252 ± 0.483
1.502AspPhe: 1.502 ± 0.75
9.009AspGly: 9.009 ± 0.326
1.502AspHis: 1.502 ± 0.75
1.502AspIle: 1.502 ± 0.75
1.502AspLys: 1.502 ± 0.75
6.006AspLeu: 6.006 ± 0.217
0.0AspMet: 0.0 ± 0.0
0.751AspAsn: 0.751 ± 0.375
5.255AspPro: 5.255 ± 0.592
1.502AspGln: 1.502 ± 0.75
1.502AspArg: 1.502 ± 0.75
3.754AspSer: 3.754 ± 0.266
2.252AspThr: 2.252 ± 0.483
6.757AspVal: 6.757 ± 3.058
1.502AspTrp: 1.502 ± 0.75
3.754AspTyr: 3.754 ± 1.342
0.0AspXaa: 0.0 ± 0.0
Glu
4.505GluAla: 4.505 ± 0.641
0.0GluCys: 0.0 ± 0.0
3.754GluAsp: 3.754 ± 1.342
3.003GluGlu: 3.003 ± 1.499
0.751GluPhe: 0.751 ± 0.375
0.0GluGly: 0.0 ± 0.0
1.502GluHis: 1.502 ± 0.858
2.252GluIle: 2.252 ± 1.124
1.502GluLys: 1.502 ± 0.858
6.006GluLeu: 6.006 ± 2.998
0.751GluMet: 0.751 ± 0.375
3.754GluAsn: 3.754 ± 0.266
0.0GluPro: 0.0 ± 0.0
3.754GluGln: 3.754 ± 1.874
3.003GluArg: 3.003 ± 1.499
0.751GluSer: 0.751 ± 0.375
3.003GluThr: 3.003 ± 1.499
3.003GluVal: 3.003 ± 1.716
1.502GluTrp: 1.502 ± 0.858
2.252GluTyr: 2.252 ± 0.483
0.0GluXaa: 0.0 ± 0.0
Phe
3.003PheAla: 3.003 ± 0.109
0.751PheCys: 0.751 ± 0.375
3.003PheAsp: 3.003 ± 3.324
2.252PheGlu: 2.252 ± 0.483
0.0PhePhe: 0.0 ± 0.0
1.502PheGly: 1.502 ± 0.75
0.751PheHis: 0.751 ± 0.375
2.252PheIle: 2.252 ± 1.124
1.502PheLys: 1.502 ± 0.75
3.003PheLeu: 3.003 ± 1.716
0.751PheMet: 0.751 ± 0.375
0.751PheAsn: 0.751 ± 0.375
2.252PhePro: 2.252 ± 2.091
1.502PheGln: 1.502 ± 0.75
2.252PheArg: 2.252 ± 1.124
3.003PheSer: 3.003 ± 3.324
3.003PheThr: 3.003 ± 1.716
3.003PheVal: 3.003 ± 0.109
1.502PheTrp: 1.502 ± 0.75
0.751PheTyr: 0.751 ± 0.375
0.0PheXaa: 0.0 ± 0.0
Gly
6.006GlyAla: 6.006 ± 3.433
0.751GlyCys: 0.751 ± 0.375
5.255GlyAsp: 5.255 ± 2.2
2.252GlyGlu: 2.252 ± 0.483
3.003GlyPhe: 3.003 ± 0.109
3.003GlyGly: 3.003 ± 1.716
0.751GlyHis: 0.751 ± 0.375
3.003GlyIle: 3.003 ± 1.499
3.003GlyLys: 3.003 ± 1.716
3.003GlyLeu: 3.003 ± 0.109
0.0GlyMet: 0.0 ± 0.0
0.751GlyAsn: 0.751 ± 0.375
5.255GlyPro: 5.255 ± 2.624
4.505GlyGln: 4.505 ± 0.641
8.258GlyArg: 8.258 ± 2.515
8.258GlySer: 8.258 ± 5.524
4.505GlyThr: 4.505 ± 4.183
3.003GlyVal: 3.003 ± 1.499
0.751GlyTrp: 0.751 ± 0.375
3.003GlyTyr: 3.003 ± 0.109
0.0GlyXaa: 0.0 ± 0.0
His
2.252HisAla: 2.252 ± 0.483
0.0HisCys: 0.0 ± 0.0
0.751HisAsp: 0.751 ± 0.375
1.502HisGlu: 1.502 ± 0.75
0.751HisPhe: 0.751 ± 0.375
1.502HisGly: 1.502 ± 0.75
2.252HisHis: 2.252 ± 1.124
2.252HisIle: 2.252 ± 1.124
2.252HisLys: 2.252 ± 0.483
0.751HisLeu: 0.751 ± 0.375
0.0HisMet: 0.0 ± 0.0
2.252HisAsn: 2.252 ± 2.091
0.751HisPro: 0.751 ± 0.375
1.502HisGln: 1.502 ± 0.75
2.252HisArg: 2.252 ± 1.124
2.252HisSer: 2.252 ± 0.483
0.751HisThr: 0.751 ± 0.375
3.003HisVal: 3.003 ± 0.109
0.0HisTrp: 0.0 ± 0.0
2.252HisTyr: 2.252 ± 1.124
0.0HisXaa: 0.0 ± 0.0
Ile
3.754IleAla: 3.754 ± 0.266
3.003IleCys: 3.003 ± 1.499
3.003IleAsp: 3.003 ± 0.109
0.751IleGlu: 0.751 ± 1.233
1.502IlePhe: 1.502 ± 0.75
4.505IleGly: 4.505 ± 0.641
2.252IleHis: 2.252 ± 0.483
2.252IleIle: 2.252 ± 0.483
2.252IleLys: 2.252 ± 1.124
2.252IleLeu: 2.252 ± 2.091
0.0IleMet: 0.0 ± 0.0
0.751IleAsn: 0.751 ± 1.233
4.505IlePro: 4.505 ± 2.575
3.003IleGln: 3.003 ± 1.716
0.0IleArg: 0.0 ± 0.0
4.505IleSer: 4.505 ± 2.249
2.252IleThr: 2.252 ± 1.124
6.006IleVal: 6.006 ± 1.391
1.502IleTrp: 1.502 ± 0.75
2.252IleTyr: 2.252 ± 1.124
0.0IleXaa: 0.0 ± 0.0
Lys
2.252LysAla: 2.252 ± 1.124
1.502LysCys: 1.502 ± 0.75
5.255LysAsp: 5.255 ± 0.592
0.751LysGlu: 0.751 ± 0.375
0.751LysPhe: 0.751 ± 1.233
1.502LysGly: 1.502 ± 0.858
0.751LysHis: 0.751 ± 0.375
2.252LysIle: 2.252 ± 1.124
5.255LysLys: 5.255 ± 0.592
3.003LysLeu: 3.003 ± 1.499
0.751LysMet: 0.751 ± 0.375
0.751LysAsn: 0.751 ± 1.233
6.006LysPro: 6.006 ± 0.217
0.751LysGln: 0.751 ± 0.375
3.003LysArg: 3.003 ± 0.109
2.252LysSer: 2.252 ± 1.124
4.505LysThr: 4.505 ± 2.249
1.502LysVal: 1.502 ± 0.75
0.751LysTrp: 0.751 ± 1.233
1.502LysTyr: 1.502 ± 0.75
0.0LysXaa: 0.0 ± 0.0
Leu
6.006LeuAla: 6.006 ± 0.217
1.502LeuCys: 1.502 ± 0.858
2.252LeuAsp: 2.252 ± 1.124
3.003LeuGlu: 3.003 ± 0.109
2.252LeuPhe: 2.252 ± 2.091
6.006LeuGly: 6.006 ± 0.217
0.0LeuHis: 0.0 ± 0.0
3.754LeuIle: 3.754 ± 1.874
3.754LeuLys: 3.754 ± 0.266
7.508LeuLeu: 7.508 ± 0.532
0.751LeuMet: 0.751 ± 0.375
3.754LeuAsn: 3.754 ± 0.266
5.255LeuPro: 5.255 ± 1.016
1.502LeuGln: 1.502 ± 0.858
8.258LeuArg: 8.258 ± 2.515
10.511LeuSer: 10.511 ± 2.032
5.255LeuThr: 5.255 ± 1.016
3.754LeuVal: 3.754 ± 1.874
1.502LeuTrp: 1.502 ± 0.858
0.751LeuTyr: 0.751 ± 1.233
0.0LeuXaa: 0.0 ± 0.0
Met
1.502MetAla: 1.502 ± 0.858
0.751MetCys: 0.751 ± 1.233
0.751MetAsp: 0.751 ± 0.375
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
2.252MetHis: 2.252 ± 1.124
0.751MetIle: 0.751 ± 0.375
0.0MetLys: 0.0 ± 0.0
2.252MetLeu: 2.252 ± 1.124
0.751MetMet: 0.751 ± 0.375
0.0MetAsn: 0.0 ± 0.0
0.751MetPro: 0.751 ± 0.375
0.751MetGln: 0.751 ± 0.375
0.751MetArg: 0.751 ± 0.375
2.252MetSer: 2.252 ± 0.483
2.252MetThr: 2.252 ± 0.483
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.252AsnAla: 2.252 ± 0.483
0.751AsnCys: 0.751 ± 0.375
2.252AsnAsp: 2.252 ± 1.124
3.003AsnGlu: 3.003 ± 1.499
0.0AsnPhe: 0.0 ± 0.0
3.003AsnGly: 3.003 ± 1.499
1.502AsnHis: 1.502 ± 0.75
3.003AsnIle: 3.003 ± 0.109
1.502AsnLys: 1.502 ± 0.75
3.754AsnLeu: 3.754 ± 0.266
0.751AsnMet: 0.751 ± 0.347
1.502AsnAsn: 1.502 ± 0.75
3.003AsnPro: 3.003 ± 1.716
1.502AsnGln: 1.502 ± 0.75
4.505AsnArg: 4.505 ± 0.967
6.006AsnSer: 6.006 ± 3.433
1.502AsnThr: 1.502 ± 0.858
2.252AsnVal: 2.252 ± 2.091
0.0AsnTrp: 0.0 ± 0.0
3.003AsnTyr: 3.003 ± 0.109
0.0AsnXaa: 0.0 ± 0.0
Pro
3.754ProAla: 3.754 ± 0.266
0.751ProCys: 0.751 ± 0.375
1.502ProAsp: 1.502 ± 0.75
3.003ProGlu: 3.003 ± 1.499
4.505ProPhe: 4.505 ± 0.641
5.255ProGly: 5.255 ± 1.016
1.502ProHis: 1.502 ± 0.75
2.252ProIle: 2.252 ± 2.091
2.252ProLys: 2.252 ± 0.483
5.255ProLeu: 5.255 ± 2.624
0.751ProMet: 0.751 ± 1.233
3.754ProAsn: 3.754 ± 0.266
1.502ProPro: 1.502 ± 2.466
2.252ProGln: 2.252 ± 1.124
4.505ProArg: 4.505 ± 2.575
3.754ProSer: 3.754 ± 1.342
6.757ProThr: 6.757 ± 4.666
3.754ProVal: 3.754 ± 1.342
0.751ProTrp: 0.751 ± 0.375
0.751ProTyr: 0.751 ± 0.375
0.0ProXaa: 0.0 ± 0.0
Gln
4.505GlnAla: 4.505 ± 0.641
0.751GlnCys: 0.751 ± 1.233
1.502GlnAsp: 1.502 ± 0.75
0.751GlnGlu: 0.751 ± 0.375
1.502GlnPhe: 1.502 ± 0.75
3.003GlnGly: 3.003 ± 1.716
0.751GlnHis: 0.751 ± 0.375
1.502GlnIle: 1.502 ± 0.75
2.252GlnLys: 2.252 ± 1.124
4.505GlnLeu: 4.505 ± 2.249
0.0GlnMet: 0.0 ± 0.0
1.502GlnAsn: 1.502 ± 0.75
2.252GlnPro: 2.252 ± 2.091
3.754GlnGln: 3.754 ± 1.874
3.003GlnArg: 3.003 ± 0.109
2.252GlnSer: 2.252 ± 1.124
3.003GlnThr: 3.003 ± 0.109
1.502GlnVal: 1.502 ± 0.75
0.0GlnTrp: 0.0 ± 0.0
0.751GlnTyr: 0.751 ± 0.375
0.0GlnXaa: 0.0 ± 0.0
Arg
6.006ArgAla: 6.006 ± 2.998
0.0ArgCys: 0.0 ± 0.0
3.003ArgAsp: 3.003 ± 0.109
5.255ArgGlu: 5.255 ± 2.624
5.255ArgPhe: 5.255 ± 2.2
5.255ArgGly: 5.255 ± 2.2
1.502ArgHis: 1.502 ± 0.75
3.754ArgIle: 3.754 ± 2.95
3.003ArgLys: 3.003 ± 1.499
6.757ArgLeu: 6.757 ± 0.158
3.003ArgMet: 3.003 ± 0.109
5.255ArgAsn: 5.255 ± 1.016
3.003ArgPro: 3.003 ± 1.716
2.252ArgGln: 2.252 ± 1.124
5.255ArgArg: 5.255 ± 2.624
2.252ArgSer: 2.252 ± 1.124
2.252ArgThr: 2.252 ± 1.124
1.502ArgVal: 1.502 ± 0.75
0.751ArgTrp: 0.751 ± 0.375
3.003ArgTyr: 3.003 ± 1.716
0.0ArgXaa: 0.0 ± 0.0
Ser
4.505SerAla: 4.505 ± 0.967
0.751SerCys: 0.751 ± 0.375
6.006SerAsp: 6.006 ± 0.217
2.252SerGlu: 2.252 ± 0.483
3.754SerPhe: 3.754 ± 2.95
6.757SerGly: 6.757 ± 0.158
3.754SerHis: 3.754 ± 0.266
5.255SerIle: 5.255 ± 0.592
1.502SerLys: 1.502 ± 0.75
9.009SerLeu: 9.009 ± 1.934
1.502SerMet: 1.502 ± 0.75
4.505SerAsn: 4.505 ± 2.575
4.505SerPro: 4.505 ± 0.641
2.252SerGln: 2.252 ± 0.483
6.006SerArg: 6.006 ± 0.217
5.255SerSer: 5.255 ± 0.592
6.006SerThr: 6.006 ± 0.217
6.757SerVal: 6.757 ± 0.158
1.502SerTrp: 1.502 ± 0.75
1.502SerTyr: 1.502 ± 0.858
0.0SerXaa: 0.0 ± 0.0
Thr
6.757ThrAla: 6.757 ± 1.765
0.751ThrCys: 0.751 ± 0.375
7.508ThrAsp: 7.508 ± 1.076
7.508ThrGlu: 7.508 ± 2.14
2.252ThrPhe: 2.252 ± 1.124
3.003ThrGly: 3.003 ± 3.324
0.751ThrHis: 0.751 ± 1.233
5.255ThrIle: 5.255 ± 0.592
3.754ThrLys: 3.754 ± 1.342
3.003ThrLeu: 3.003 ± 1.499
0.751ThrMet: 0.751 ± 0.375
2.252ThrAsn: 2.252 ± 3.699
3.003ThrPro: 3.003 ± 1.499
2.252ThrGln: 2.252 ± 0.483
2.252ThrArg: 2.252 ± 2.091
3.754ThrSer: 3.754 ± 1.342
2.252ThrThr: 2.252 ± 0.483
3.754ThrVal: 3.754 ± 1.874
0.751ThrTrp: 0.751 ± 1.233
2.252ThrTyr: 2.252 ± 1.124
0.0ThrXaa: 0.0 ± 0.0
Val
6.757ValAla: 6.757 ± 1.45
0.751ValCys: 0.751 ± 0.375
3.754ValAsp: 3.754 ± 0.266
3.003ValGlu: 3.003 ± 1.499
3.003ValPhe: 3.003 ± 0.109
3.754ValGly: 3.754 ± 1.342
3.003ValHis: 3.003 ± 0.109
4.505ValIle: 4.505 ± 2.575
3.003ValLys: 3.003 ± 1.499
5.255ValLeu: 5.255 ± 3.808
2.252ValMet: 2.252 ± 0.731
4.505ValAsn: 4.505 ± 0.641
6.006ValPro: 6.006 ± 1.391
2.252ValGln: 2.252 ± 1.124
3.754ValArg: 3.754 ± 1.342
5.255ValSer: 5.255 ± 1.016
3.003ValThr: 3.003 ± 0.109
5.255ValVal: 5.255 ± 1.016
0.0ValTrp: 0.0 ± 0.0
0.751ValTyr: 0.751 ± 0.375
0.0ValXaa: 0.0 ± 0.0
Trp
1.502TrpAla: 1.502 ± 0.75
0.751TrpCys: 0.751 ± 0.375
0.751TrpAsp: 0.751 ± 0.375
1.502TrpGlu: 1.502 ± 2.466
0.751TrpPhe: 0.751 ± 0.375
0.751TrpGly: 0.751 ± 1.233
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.502TrpLeu: 1.502 ± 0.75
0.0TrpMet: 0.0 ± 0.0
0.751TrpAsn: 0.751 ± 0.375
0.751TrpPro: 0.751 ± 0.375
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.751TrpSer: 0.751 ± 0.375
0.751TrpThr: 0.751 ± 1.233
2.252TrpVal: 2.252 ± 1.124
0.751TrpTrp: 0.751 ± 1.233
0.751TrpTyr: 0.751 ± 0.375
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.505TyrAla: 4.505 ± 2.249
0.751TyrCys: 0.751 ± 1.233
2.252TyrAsp: 2.252 ± 1.124
0.0TyrGlu: 0.0 ± 0.0
2.252TyrPhe: 2.252 ± 2.091
3.003TyrGly: 3.003 ± 1.499
0.751TyrHis: 0.751 ± 0.375
0.751TyrIle: 0.751 ± 0.375
0.751TyrLys: 0.751 ± 0.375
3.003TyrLeu: 3.003 ± 1.499
0.751TyrMet: 0.751 ± 0.375
0.751TyrAsn: 0.751 ± 0.375
0.0TyrPro: 0.0 ± 0.0
2.252TyrGln: 2.252 ± 0.483
0.751TyrArg: 0.751 ± 1.233
6.006TyrSer: 6.006 ± 3.433
2.252TyrThr: 2.252 ± 1.124
3.754TyrVal: 3.754 ± 1.342
0.0TyrTrp: 0.0 ± 0.0
1.502TyrTyr: 1.502 ± 0.858
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1333 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski