Amino acid dipepetide frequency for Terrapene carolina carolina ranavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.038AlaAla: 10.038 ± 0.976
1.626AlaCys: 1.626 ± 0.213
4.383AlaAsp: 4.383 ± 0.347
5.584AlaGlu: 5.584 ± 0.515
2.722AlaPhe: 2.722 ± 0.372
7.034AlaGly: 7.034 ± 0.617
1.697AlaHis: 1.697 ± 0.242
2.439AlaIle: 2.439 ± 0.309
4.559AlaLys: 4.559 ± 0.491
7.14AlaLeu: 7.14 ± 0.634
3.075AlaMet: 3.075 ± 0.306
1.838AlaAsn: 1.838 ± 0.228
4.453AlaPro: 4.453 ± 0.43
2.615AlaGln: 2.615 ± 0.277
5.054AlaArg: 5.054 ± 0.504
6.185AlaSer: 6.185 ± 0.577
4.383AlaThr: 4.383 ± 0.373
8.659AlaVal: 8.659 ± 0.672
1.202AlaTrp: 1.202 ± 0.245
2.58AlaTyr: 2.58 ± 0.285
0.0AlaXaa: 0.0 ± 0.0
Cys
1.838CysAla: 1.838 ± 0.303
0.566CysCys: 0.566 ± 0.16
1.343CysAsp: 1.343 ± 0.23
1.025CysGlu: 1.025 ± 0.187
0.53CysPhe: 0.53 ± 0.132
1.697CysGly: 1.697 ± 0.262
0.601CysHis: 0.601 ± 0.164
0.742CysIle: 0.742 ± 0.173
1.52CysLys: 1.52 ± 0.228
1.343CysLeu: 1.343 ± 0.276
0.672CysMet: 0.672 ± 0.147
0.601CysAsn: 0.601 ± 0.166
1.732CysPro: 1.732 ± 0.299
0.636CysGln: 0.636 ± 0.171
1.59CysArg: 1.59 ± 0.256
1.555CysSer: 1.555 ± 0.231
0.813CysThr: 0.813 ± 0.167
1.449CysVal: 1.449 ± 0.198
0.459CysTrp: 0.459 ± 0.112
0.636CysTyr: 0.636 ± 0.149
0.0CysXaa: 0.0 ± 0.0
Asp
5.231AspAla: 5.231 ± 0.414
1.414AspCys: 1.414 ± 0.187
3.464AspAsp: 3.464 ± 0.419
2.969AspGlu: 2.969 ± 0.379
1.59AspPhe: 1.59 ± 0.281
4.595AspGly: 4.595 ± 0.542
1.131AspHis: 1.131 ± 0.148
2.297AspIle: 2.297 ± 0.308
2.722AspLys: 2.722 ± 0.311
5.302AspLeu: 5.302 ± 0.496
2.297AspMet: 2.297 ± 0.272
2.156AspAsn: 2.156 ± 0.294
4.701AspPro: 4.701 ± 0.459
1.414AspGln: 1.414 ± 0.275
3.923AspArg: 3.923 ± 0.381
4.63AspSer: 4.63 ± 0.521
2.615AspThr: 2.615 ± 0.308
5.019AspVal: 5.019 ± 0.409
0.954AspTrp: 0.954 ± 0.2
2.297AspTyr: 2.297 ± 0.241
0.0AspXaa: 0.0 ± 0.0
Glu
5.938GluAla: 5.938 ± 0.6
1.343GluCys: 1.343 ± 0.254
3.747GluAsp: 3.747 ± 0.479
4.1GluGlu: 4.1 ± 0.737
1.873GluPhe: 1.873 ± 0.234
3.676GluGly: 3.676 ± 0.356
0.848GluHis: 0.848 ± 0.159
1.803GluIle: 1.803 ± 0.22
3.252GluLys: 3.252 ± 0.343
3.358GluLeu: 3.358 ± 0.353
2.156GluMet: 2.156 ± 0.257
1.06GluAsn: 1.06 ± 0.191
2.898GluPro: 2.898 ± 0.352
1.803GluGln: 1.803 ± 0.448
3.959GluArg: 3.959 ± 0.382
3.853GluSer: 3.853 ± 0.487
3.499GluThr: 3.499 ± 0.399
3.747GluVal: 3.747 ± 0.454
1.237GluTrp: 1.237 ± 0.211
1.838GluTyr: 1.838 ± 0.227
0.0GluXaa: 0.0 ± 0.0
Phe
2.792PheAla: 2.792 ± 0.34
0.742PheCys: 0.742 ± 0.171
1.52PheAsp: 1.52 ± 0.24
1.732PheGlu: 1.732 ± 0.226
1.166PhePhe: 1.166 ± 0.203
2.403PheGly: 2.403 ± 0.295
0.636PheHis: 0.636 ± 0.177
1.166PheIle: 1.166 ± 0.231
1.378PheLys: 1.378 ± 0.171
2.898PheLeu: 2.898 ± 0.312
0.919PheMet: 0.919 ± 0.172
1.272PheAsn: 1.272 ± 0.197
2.121PhePro: 2.121 ± 0.296
0.707PheGln: 0.707 ± 0.128
2.368PheArg: 2.368 ± 0.358
2.651PheSer: 2.651 ± 0.267
1.873PheThr: 1.873 ± 0.299
2.898PheVal: 2.898 ± 0.36
0.318PheTrp: 0.318 ± 0.108
1.06PheTyr: 1.06 ± 0.189
0.0PheXaa: 0.0 ± 0.0
Gly
5.655GlyAla: 5.655 ± 0.418
1.732GlyCys: 1.732 ± 0.282
4.135GlyAsp: 4.135 ± 0.444
3.322GlyGlu: 3.322 ± 0.337
2.757GlyPhe: 2.757 ± 0.331
5.796GlyGly: 5.796 ± 0.599
2.121GlyHis: 2.121 ± 0.298
2.227GlyIle: 2.227 ± 0.264
4.312GlyLys: 4.312 ± 0.373
5.796GlyLeu: 5.796 ± 0.57
2.015GlyMet: 2.015 ± 0.276
1.378GlyAsn: 1.378 ± 0.26
4.524GlyPro: 4.524 ± 0.578
1.979GlyGln: 1.979 ± 0.256
5.903GlyArg: 5.903 ± 0.642
5.69GlySer: 5.69 ± 0.459
4.489GlyThr: 4.489 ± 0.422
5.938GlyVal: 5.938 ± 0.493
1.414GlyTrp: 1.414 ± 0.251
2.58GlyTyr: 2.58 ± 0.269
0.0GlyXaa: 0.0 ± 0.0
His
1.732HisAla: 1.732 ± 0.201
0.283HisCys: 0.283 ± 0.091
1.06HisAsp: 1.06 ± 0.213
0.707HisGlu: 0.707 ± 0.181
0.53HisPhe: 0.53 ± 0.112
2.05HisGly: 2.05 ± 0.316
0.566HisHis: 0.566 ± 0.171
0.848HisIle: 0.848 ± 0.143
0.919HisLys: 0.919 ± 0.196
2.191HisLeu: 2.191 ± 0.327
0.601HisMet: 0.601 ± 0.145
0.672HisAsn: 0.672 ± 0.217
1.52HisPro: 1.52 ± 0.239
0.813HisGln: 0.813 ± 0.194
1.449HisArg: 1.449 ± 0.215
1.52HisSer: 1.52 ± 0.284
1.343HisThr: 1.343 ± 0.249
2.085HisVal: 2.085 ± 0.285
0.247HisTrp: 0.247 ± 0.094
0.884HisTyr: 0.884 ± 0.175
0.0HisXaa: 0.0 ± 0.0
Ile
2.368IleAla: 2.368 ± 0.287
0.672IleCys: 0.672 ± 0.126
1.979IleAsp: 1.979 ± 0.265
1.59IleGlu: 1.59 ± 0.249
1.025IlePhe: 1.025 ± 0.187
1.59IleGly: 1.59 ± 0.249
0.919IleHis: 0.919 ± 0.188
1.096IleIle: 1.096 ± 0.194
2.368IleLys: 2.368 ± 0.289
3.181IleLeu: 3.181 ± 0.37
1.096IleMet: 1.096 ± 0.194
0.884IleAsn: 0.884 ± 0.19
2.262IlePro: 2.262 ± 0.296
0.848IleGln: 0.848 ± 0.199
2.58IleArg: 2.58 ± 0.312
2.297IleSer: 2.297 ± 0.263
1.484IleThr: 1.484 ± 0.286
2.898IleVal: 2.898 ± 0.36
0.247IleTrp: 0.247 ± 0.096
0.919IleTyr: 0.919 ± 0.227
0.0IleXaa: 0.0 ± 0.0
Lys
4.665LysAla: 4.665 ± 0.503
0.884LysCys: 0.884 ± 0.179
3.075LysAsp: 3.075 ± 0.356
3.146LysGlu: 3.146 ± 0.376
1.449LysPhe: 1.449 ± 0.254
4.206LysGly: 4.206 ± 0.398
0.707LysHis: 0.707 ± 0.131
2.439LysIle: 2.439 ± 0.271
3.747LysLys: 3.747 ± 0.538
4.135LysLeu: 4.135 ± 0.483
2.05LysMet: 2.05 ± 0.251
1.873LysAsn: 1.873 ± 0.258
3.464LysPro: 3.464 ± 0.587
1.484LysGln: 1.484 ± 0.296
5.09LysArg: 5.09 ± 0.759
3.959LysSer: 3.959 ± 0.844
3.747LysThr: 3.747 ± 0.315
3.676LysVal: 3.676 ± 0.339
0.636LysTrp: 0.636 ± 0.181
1.838LysTyr: 1.838 ± 0.221
0.0LysXaa: 0.0 ± 0.0
Leu
6.609LeuAla: 6.609 ± 0.562
2.085LeuCys: 2.085 ± 0.329
5.266LeuAsp: 5.266 ± 0.44
5.16LeuGlu: 5.16 ± 0.486
2.828LeuPhe: 2.828 ± 0.318
5.62LeuGly: 5.62 ± 0.521
2.05LeuHis: 2.05 ± 0.415
2.58LeuIle: 2.58 ± 0.336
4.665LeuLys: 4.665 ± 0.416
6.433LeuLeu: 6.433 ± 0.749
2.262LeuMet: 2.262 ± 0.222
2.615LeuAsn: 2.615 ± 0.29
4.1LeuPro: 4.1 ± 0.494
1.626LeuGln: 1.626 ± 0.256
6.115LeuArg: 6.115 ± 0.508
5.903LeuSer: 5.903 ± 0.485
5.196LeuThr: 5.196 ± 0.495
5.62LeuVal: 5.62 ± 0.442
1.025LeuTrp: 1.025 ± 0.202
2.262LeuTyr: 2.262 ± 0.274
0.0LeuXaa: 0.0 ± 0.0
Met
3.322MetAla: 3.322 ± 0.384
0.813MetCys: 0.813 ± 0.218
2.156MetAsp: 2.156 ± 0.229
1.979MetGlu: 1.979 ± 0.273
1.166MetPhe: 1.166 ± 0.227
2.757MetGly: 2.757 ± 0.271
0.707MetHis: 0.707 ± 0.179
0.636MetIle: 0.636 ± 0.131
0.919MetLys: 0.919 ± 0.187
2.05MetLeu: 2.05 ± 0.266
0.848MetMet: 0.848 ± 0.18
0.353MetAsn: 0.353 ± 0.103
1.449MetPro: 1.449 ± 0.225
0.742MetGln: 0.742 ± 0.189
2.156MetArg: 2.156 ± 0.24
3.11MetSer: 3.11 ± 0.391
1.944MetThr: 1.944 ± 0.247
2.333MetVal: 2.333 ± 0.306
0.459MetTrp: 0.459 ± 0.107
0.742MetTyr: 0.742 ± 0.226
0.0MetXaa: 0.0 ± 0.0
Asn
2.297AsnAla: 2.297 ± 0.265
0.495AsnCys: 0.495 ± 0.135
0.919AsnAsp: 0.919 ± 0.154
0.954AsnGlu: 0.954 ± 0.165
0.636AsnPhe: 0.636 ± 0.131
1.803AsnGly: 1.803 ± 0.223
0.459AsnHis: 0.459 ± 0.102
1.202AsnIle: 1.202 ± 0.249
1.096AsnLys: 1.096 ± 0.19
2.828AsnLeu: 2.828 ± 0.373
0.919AsnMet: 0.919 ± 0.179
0.813AsnAsn: 0.813 ± 0.205
2.297AsnPro: 2.297 ± 0.443
0.636AsnGln: 0.636 ± 0.118
1.52AsnArg: 1.52 ± 0.234
1.803AsnSer: 1.803 ± 0.219
1.414AsnThr: 1.414 ± 0.269
2.863AsnVal: 2.863 ± 0.36
0.53AsnTrp: 0.53 ± 0.121
1.096AsnTyr: 1.096 ± 0.177
0.0AsnXaa: 0.0 ± 0.0
Pro
6.009ProAla: 6.009 ± 0.672
1.202ProCys: 1.202 ± 0.216
3.782ProAsp: 3.782 ± 0.316
4.453ProGlu: 4.453 ± 0.523
2.121ProPhe: 2.121 ± 0.263
4.241ProGly: 4.241 ± 0.511
1.944ProHis: 1.944 ± 0.295
1.838ProIle: 1.838 ± 0.268
3.534ProLys: 3.534 ± 0.605
4.277ProLeu: 4.277 ± 0.5
1.343ProMet: 1.343 ± 0.208
1.308ProAsn: 1.308 ± 0.242
4.701ProPro: 4.701 ± 0.694
2.121ProGln: 2.121 ± 0.315
3.817ProArg: 3.817 ± 0.509
4.913ProSer: 4.913 ± 0.531
3.252ProThr: 3.252 ± 0.496
6.892ProVal: 6.892 ± 0.725
1.025ProTrp: 1.025 ± 0.259
1.555ProTyr: 1.555 ± 0.23
0.0ProXaa: 0.0 ± 0.0
Gln
2.368GlnAla: 2.368 ± 0.268
0.742GlnCys: 0.742 ± 0.165
2.05GlnAsp: 2.05 ± 0.304
2.05GlnGlu: 2.05 ± 0.319
0.707GlnPhe: 0.707 ± 0.148
1.979GlnGly: 1.979 ± 0.294
0.636GlnHis: 0.636 ± 0.169
0.99GlnIle: 0.99 ± 0.171
1.449GlnLys: 1.449 ± 0.256
1.767GlnLeu: 1.767 ± 0.318
0.636GlnMet: 0.636 ± 0.177
0.813GlnAsn: 0.813 ± 0.179
1.767GlnPro: 1.767 ± 0.419
1.767GlnGln: 1.767 ± 0.659
1.944GlnArg: 1.944 ± 0.284
2.121GlnSer: 2.121 ± 0.296
1.873GlnThr: 1.873 ± 0.344
2.156GlnVal: 2.156 ± 0.291
0.389GlnTrp: 0.389 ± 0.126
0.672GlnTyr: 0.672 ± 0.155
0.0GlnXaa: 0.0 ± 0.0
Arg
5.231ArgAla: 5.231 ± 0.461
1.166ArgCys: 1.166 ± 0.195
4.948ArgAsp: 4.948 ± 0.452
4.241ArgGlu: 4.241 ± 0.388
2.156ArgPhe: 2.156 ± 0.249
5.408ArgGly: 5.408 ± 0.497
1.732ArgHis: 1.732 ± 0.28
2.015ArgIle: 2.015 ± 0.253
4.736ArgLys: 4.736 ± 0.806
5.867ArgLeu: 5.867 ± 0.415
2.121ArgMet: 2.121 ± 0.297
2.156ArgAsn: 2.156 ± 0.373
4.665ArgPro: 4.665 ± 0.562
2.439ArgGln: 2.439 ± 0.315
6.433ArgArg: 6.433 ± 0.781
3.605ArgSer: 3.605 ± 0.435
3.676ArgThr: 3.676 ± 0.403
5.69ArgVal: 5.69 ± 0.523
0.99ArgTrp: 0.99 ± 0.19
2.156ArgTyr: 2.156 ± 0.247
0.0ArgXaa: 0.0 ± 0.0
Ser
6.291SerAla: 6.291 ± 0.594
1.626SerCys: 1.626 ± 0.26
5.019SerAsp: 5.019 ± 0.383
3.747SerGlu: 3.747 ± 0.395
2.898SerPhe: 2.898 ± 0.337
5.655SerGly: 5.655 ± 0.436
1.626SerHis: 1.626 ± 0.282
1.979SerIle: 1.979 ± 0.237
3.534SerLys: 3.534 ± 0.464
6.291SerLeu: 6.291 ± 0.601
1.873SerMet: 1.873 ± 0.298
1.803SerAsn: 1.803 ± 0.274
5.69SerPro: 5.69 ± 1.135
2.05SerGln: 2.05 ± 0.291
4.383SerArg: 4.383 ± 0.5
5.372SerSer: 5.372 ± 0.565
3.11SerThr: 3.11 ± 0.33
6.15SerVal: 6.15 ± 0.501
1.308SerTrp: 1.308 ± 0.208
1.661SerTyr: 1.661 ± 0.22
0.0SerXaa: 0.0 ± 0.0
Thr
5.408ThrAla: 5.408 ± 0.538
1.202ThrCys: 1.202 ± 0.21
3.64ThrAsp: 3.64 ± 0.353
2.615ThrGlu: 2.615 ± 0.316
2.191ThrPhe: 2.191 ± 0.26
4.948ThrGly: 4.948 ± 0.484
0.53ThrHis: 0.53 ± 0.12
1.873ThrIle: 1.873 ± 0.216
2.686ThrLys: 2.686 ± 0.32
4.665ThrLeu: 4.665 ± 0.431
1.944ThrMet: 1.944 ± 0.228
1.06ThrAsn: 1.06 ± 0.191
4.171ThrPro: 4.171 ± 0.511
1.59ThrGln: 1.59 ± 0.291
3.393ThrArg: 3.393 ± 0.336
2.969ThrSer: 2.969 ± 0.422
2.085ThrThr: 2.085 ± 0.408
6.009ThrVal: 6.009 ± 0.413
0.495ThrTrp: 0.495 ± 0.171
1.308ThrTyr: 1.308 ± 0.249
0.0ThrXaa: 0.0 ± 0.0
Val
6.291ValAla: 6.291 ± 0.458
1.767ValCys: 1.767 ± 0.273
4.878ValAsp: 4.878 ± 0.49
4.277ValGlu: 4.277 ± 0.462
2.969ValPhe: 2.969 ± 0.302
4.878ValGly: 4.878 ± 0.503
2.403ValHis: 2.403 ± 0.345
2.333ValIle: 2.333 ± 0.242
6.362ValLys: 6.362 ± 0.725
6.928ValLeu: 6.928 ± 0.579
2.58ValMet: 2.58 ± 0.311
2.439ValAsn: 2.439 ± 0.331
5.019ValPro: 5.019 ± 0.556
2.545ValGln: 2.545 ± 0.304
6.998ValArg: 6.998 ± 0.537
6.574ValSer: 6.574 ± 0.531
4.842ValThr: 4.842 ± 0.507
6.821ValVal: 6.821 ± 0.542
1.237ValTrp: 1.237 ± 0.177
2.403ValTyr: 2.403 ± 0.291
0.0ValXaa: 0.0 ± 0.0
Trp
0.813TrpAla: 0.813 ± 0.254
0.283TrpCys: 0.283 ± 0.089
1.06TrpAsp: 1.06 ± 0.192
0.884TrpGlu: 0.884 ± 0.197
0.566TrpPhe: 0.566 ± 0.151
0.99TrpGly: 0.99 ± 0.171
0.353TrpHis: 0.353 ± 0.131
0.495TrpIle: 0.495 ± 0.125
0.848TrpLys: 0.848 ± 0.16
1.484TrpLeu: 1.484 ± 0.194
0.459TrpMet: 0.459 ± 0.107
0.636TrpAsn: 0.636 ± 0.144
0.707TrpPro: 0.707 ± 0.156
0.212TrpGln: 0.212 ± 0.084
0.954TrpArg: 0.954 ± 0.183
0.884TrpSer: 0.884 ± 0.172
1.484TrpThr: 1.484 ± 0.249
0.813TrpVal: 0.813 ± 0.191
0.177TrpTrp: 0.177 ± 0.081
0.495TrpTyr: 0.495 ± 0.13
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.368TyrAla: 2.368 ± 0.316
0.707TyrCys: 0.707 ± 0.154
2.297TyrAsp: 2.297 ± 0.327
1.449TyrGlu: 1.449 ± 0.235
0.778TyrPhe: 0.778 ± 0.152
2.439TyrGly: 2.439 ± 0.306
0.353TyrHis: 0.353 ± 0.122
1.308TyrIle: 1.308 ± 0.193
1.661TyrLys: 1.661 ± 0.226
2.085TyrLeu: 2.085 ± 0.329
0.742TyrMet: 0.742 ± 0.132
0.848TyrAsn: 0.848 ± 0.177
2.085TyrPro: 2.085 ± 0.277
0.848TyrGln: 0.848 ± 0.15
1.803TyrArg: 1.803 ± 0.229
2.474TyrSer: 2.474 ± 0.267
1.661TyrThr: 1.661 ± 0.24
2.828TyrVal: 2.828 ± 0.319
0.247TyrTrp: 0.247 ± 0.1
0.848TyrTyr: 0.848 ± 0.209
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 95 proteins (28294 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski