Amino acid dipepetide frequency for Chondrostereum purpureum cryptic virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.629AlaAla: 5.629 ± 1.836
0.938AlaCys: 0.938 ± 0.776
2.814AlaAsp: 2.814 ± 1.904
2.814AlaGlu: 2.814 ± 0.493
3.752AlaPhe: 3.752 ± 0.283
2.814AlaGly: 2.814 ± 0.493
0.938AlaHis: 0.938 ± 0.635
4.69AlaIle: 4.69 ± 2.471
1.876AlaLys: 1.876 ± 0.142
8.443AlaLeu: 8.443 ± 1.343
3.752AlaMet: 3.752 ± 1.128
1.876AlaAsn: 1.876 ± 1.553
4.69AlaPro: 4.69 ± 1.06
3.752AlaGln: 3.752 ± 1.694
4.69AlaArg: 4.69 ± 0.351
6.567AlaSer: 6.567 ± 4.023
8.443AlaThr: 8.443 ± 4.165
4.69AlaVal: 4.69 ± 1.06
0.938AlaTrp: 0.938 ± 0.776
1.876AlaTyr: 1.876 ± 0.142
0.0AlaXaa: 0.0 ± 0.0
Cys
0.938CysAla: 0.938 ± 0.776
0.0CysCys: 0.0 ± 0.0
1.876CysAsp: 1.876 ± 1.269
0.0CysGlu: 0.0 ± 0.0
1.876CysPhe: 1.876 ± 1.553
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.876CysIle: 1.876 ± 1.269
0.938CysLys: 0.938 ± 0.635
0.938CysLeu: 0.938 ± 0.635
0.938CysMet: 0.938 ± 0.776
0.0CysAsn: 0.0 ± 0.0
0.938CysPro: 0.938 ± 0.776
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.938CysSer: 0.938 ± 0.635
0.0CysThr: 0.0 ± 0.0
0.938CysVal: 0.938 ± 0.776
0.0CysTrp: 0.0 ± 0.0
0.938CysTyr: 0.938 ± 0.776
0.0CysXaa: 0.0 ± 0.0
Asp
5.629AspAla: 5.629 ± 0.986
0.938AspCys: 0.938 ± 0.635
6.567AspAsp: 6.567 ± 1.621
0.938AspGlu: 0.938 ± 0.776
1.876AspPhe: 1.876 ± 1.553
3.752AspGly: 3.752 ± 0.283
0.938AspHis: 0.938 ± 0.776
6.567AspIle: 6.567 ± 1.621
3.752AspLys: 3.752 ± 1.128
4.69AspLeu: 4.69 ± 1.762
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
7.505AspPro: 7.505 ± 2.256
2.814AspGln: 2.814 ± 0.918
2.814AspArg: 2.814 ± 1.904
5.629AspSer: 5.629 ± 2.397
0.0AspThr: 0.0 ± 0.0
1.876AspVal: 1.876 ± 0.142
0.938AspTrp: 0.938 ± 0.635
2.814AspTyr: 2.814 ± 1.904
0.0AspXaa: 0.0 ± 0.0
Glu
2.814GluAla: 2.814 ± 0.493
0.938GluCys: 0.938 ± 0.776
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
0.938GluPhe: 0.938 ± 0.635
0.938GluGly: 0.938 ± 0.776
0.0GluHis: 0.0 ± 0.0
0.938GluIle: 0.938 ± 0.635
1.876GluLys: 1.876 ± 1.553
3.752GluLeu: 3.752 ± 1.128
1.876GluMet: 1.876 ± 1.553
0.938GluAsn: 0.938 ± 0.776
1.876GluPro: 1.876 ± 1.553
2.814GluGln: 2.814 ± 0.493
0.938GluArg: 0.938 ± 0.635
3.752GluSer: 3.752 ± 0.283
3.752GluThr: 3.752 ± 1.694
1.876GluVal: 1.876 ± 1.269
0.938GluTrp: 0.938 ± 0.635
2.814GluTyr: 2.814 ± 0.493
0.0GluXaa: 0.0 ± 0.0
Phe
0.938PheAla: 0.938 ± 0.635
0.0PheCys: 0.0 ± 0.0
8.443PheAsp: 8.443 ± 1.479
6.567PheGlu: 6.567 ± 0.21
4.69PhePhe: 4.69 ± 1.762
2.814PheGly: 2.814 ± 0.918
0.938PheHis: 0.938 ± 0.635
2.814PheIle: 2.814 ± 0.493
5.629PheLys: 5.629 ± 3.808
2.814PheLeu: 2.814 ± 0.918
0.0PheMet: 0.0 ± 0.0
1.876PheAsn: 1.876 ± 1.553
4.69PhePro: 4.69 ± 1.06
0.938PheGln: 0.938 ± 0.776
2.814PheArg: 2.814 ± 0.918
1.876PheSer: 1.876 ± 0.142
6.567PheThr: 6.567 ± 0.21
4.69PheVal: 4.69 ± 0.351
2.814PheTrp: 2.814 ± 0.918
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.814GlyAla: 2.814 ± 2.329
0.0GlyCys: 0.0 ± 0.0
5.629GlyAsp: 5.629 ± 1.836
0.0GlyGlu: 0.0 ± 0.0
4.69GlyPhe: 4.69 ± 1.762
0.938GlyGly: 0.938 ± 0.635
0.0GlyHis: 0.0 ± 0.0
5.629GlyIle: 5.629 ± 0.986
0.0GlyLys: 0.0 ± 0.0
4.69GlyLeu: 4.69 ± 3.174
0.938GlyMet: 0.938 ± 0.776
1.876GlyAsn: 1.876 ± 1.269
4.69GlyPro: 4.69 ± 2.471
0.938GlyGln: 0.938 ± 0.635
0.938GlyArg: 0.938 ± 0.635
3.752GlySer: 3.752 ± 0.283
5.629GlyThr: 5.629 ± 3.247
1.876GlyVal: 1.876 ± 1.269
0.938GlyTrp: 0.938 ± 0.635
3.752GlyTyr: 3.752 ± 2.539
0.0GlyXaa: 0.0 ± 0.0
His
6.567HisAla: 6.567 ± 1.621
0.0HisCys: 0.0 ± 0.0
0.938HisAsp: 0.938 ± 0.776
1.876HisGlu: 1.876 ± 1.269
0.938HisPhe: 0.938 ± 0.635
0.938HisGly: 0.938 ± 0.635
0.938HisHis: 0.938 ± 0.635
2.814HisIle: 2.814 ± 1.904
0.938HisLys: 0.938 ± 0.635
1.876HisLeu: 1.876 ± 1.269
0.0HisMet: 0.0 ± 0.0
1.876HisAsn: 1.876 ± 1.269
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.814HisArg: 2.814 ± 0.918
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.938HisVal: 0.938 ± 0.776
0.0HisTrp: 0.0 ± 0.0
2.814HisTyr: 2.814 ± 0.493
0.0HisXaa: 0.0 ± 0.0
Ile
3.752IleAla: 3.752 ± 1.694
0.938IleCys: 0.938 ± 0.776
2.814IleAsp: 2.814 ± 0.493
0.0IleGlu: 0.0 ± 0.0
3.752IlePhe: 3.752 ± 1.128
5.629IleGly: 5.629 ± 1.836
3.752IleHis: 3.752 ± 1.128
3.752IleIle: 3.752 ± 0.283
5.629IleLys: 5.629 ± 3.808
5.629IleLeu: 5.629 ± 3.808
2.814IleMet: 2.814 ± 0.36
1.876IleAsn: 1.876 ± 1.553
2.814IlePro: 2.814 ± 1.904
2.814IleGln: 2.814 ± 0.493
3.752IleArg: 3.752 ± 0.283
4.69IleSer: 4.69 ± 1.06
6.567IleThr: 6.567 ± 3.032
0.938IleVal: 0.938 ± 0.776
0.938IleTrp: 0.938 ± 0.635
0.938IleTyr: 0.938 ± 0.776
0.0IleXaa: 0.0 ± 0.0
Lys
3.752LysAla: 3.752 ± 1.128
0.938LysCys: 0.938 ± 0.635
2.814LysAsp: 2.814 ± 1.904
0.0LysGlu: 0.0 ± 0.0
1.876LysPhe: 1.876 ± 0.142
1.876LysGly: 1.876 ± 1.269
1.876LysHis: 1.876 ± 1.269
0.938LysIle: 0.938 ± 0.635
0.938LysLys: 0.938 ± 0.635
0.938LysLeu: 0.938 ± 0.635
0.938LysMet: 0.938 ± 0.776
2.814LysAsn: 2.814 ± 1.904
1.876LysPro: 1.876 ± 1.269
0.938LysGln: 0.938 ± 0.635
3.752LysArg: 3.752 ± 1.128
1.876LysSer: 1.876 ± 0.142
0.938LysThr: 0.938 ± 0.635
5.629LysVal: 5.629 ± 2.397
0.0LysTrp: 0.0 ± 0.0
0.938LysTyr: 0.938 ± 0.635
0.0LysXaa: 0.0 ± 0.0
Leu
3.752LeuAla: 3.752 ± 1.128
0.938LeuCys: 0.938 ± 0.776
6.567LeuAsp: 6.567 ± 3.032
1.876LeuGlu: 1.876 ± 1.269
8.443LeuPhe: 8.443 ± 1.479
3.752LeuGly: 3.752 ± 1.128
1.876LeuHis: 1.876 ± 0.142
4.69LeuIle: 4.69 ± 0.351
1.876LeuLys: 1.876 ± 1.269
8.443LeuLeu: 8.443 ± 1.479
1.876LeuMet: 1.876 ± 1.553
5.629LeuAsn: 5.629 ± 1.836
8.443LeuPro: 8.443 ± 0.068
0.938LeuGln: 0.938 ± 0.776
5.629LeuArg: 5.629 ± 3.808
5.629LeuSer: 5.629 ± 0.986
7.505LeuThr: 7.505 ± 0.567
5.629LeuVal: 5.629 ± 3.247
1.876LeuTrp: 1.876 ± 1.269
3.752LeuTyr: 3.752 ± 0.283
0.0LeuXaa: 0.0 ± 0.0
Met
0.938MetAla: 0.938 ± 0.776
0.0MetCys: 0.0 ± 0.0
1.876MetAsp: 1.876 ± 0.142
0.938MetGlu: 0.938 ± 0.776
1.876MetPhe: 1.876 ± 0.142
0.938MetGly: 0.938 ± 0.635
0.938MetHis: 0.938 ± 0.635
0.938MetIle: 0.938 ± 0.635
0.0MetLys: 0.0 ± 0.0
1.876MetLeu: 1.876 ± 1.553
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.938MetPro: 0.938 ± 0.776
1.876MetGln: 1.876 ± 0.142
4.69MetArg: 4.69 ± 0.351
3.752MetSer: 3.752 ± 1.694
3.752MetThr: 3.752 ± 1.694
0.938MetVal: 0.938 ± 0.776
0.938MetTrp: 0.938 ± 0.635
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.876AsnAla: 1.876 ± 1.553
1.876AsnCys: 1.876 ± 0.142
0.938AsnAsp: 0.938 ± 0.635
4.69AsnGlu: 4.69 ± 2.471
0.0AsnPhe: 0.0 ± 0.0
2.814AsnGly: 2.814 ± 1.904
2.814AsnHis: 2.814 ± 0.493
1.876AsnIle: 1.876 ± 0.142
0.938AsnLys: 0.938 ± 0.635
4.69AsnLeu: 4.69 ± 1.762
0.0AsnMet: 0.0 ± 0.0
2.814AsnAsn: 2.814 ± 0.493
0.938AsnPro: 0.938 ± 0.776
0.0AsnGln: 0.0 ± 0.0
0.938AsnArg: 0.938 ± 0.776
0.938AsnSer: 0.938 ± 0.776
4.69AsnThr: 4.69 ± 2.471
0.938AsnVal: 0.938 ± 0.776
0.0AsnTrp: 0.0 ± 0.0
1.876AsnTyr: 1.876 ± 0.142
0.0AsnXaa: 0.0 ± 0.0
Pro
9.381ProAla: 9.381 ± 3.53
0.0ProCys: 0.0 ± 0.0
3.752ProAsp: 3.752 ± 1.128
1.876ProGlu: 1.876 ± 0.142
4.69ProPhe: 4.69 ± 0.351
4.69ProGly: 4.69 ± 1.06
0.0ProHis: 0.0 ± 0.0
5.629ProIle: 5.629 ± 2.397
2.814ProLys: 2.814 ± 1.904
4.69ProLeu: 4.69 ± 1.06
2.814ProMet: 2.814 ± 0.918
3.752ProAsn: 3.752 ± 1.128
3.752ProPro: 3.752 ± 1.694
4.69ProGln: 4.69 ± 0.351
0.938ProArg: 0.938 ± 0.776
6.567ProSer: 6.567 ± 2.612
5.629ProThr: 5.629 ± 0.986
7.505ProVal: 7.505 ± 1.978
0.938ProTrp: 0.938 ± 0.635
1.876ProTyr: 1.876 ± 1.269
0.0ProXaa: 0.0 ± 0.0
Gln
7.505GlnAla: 7.505 ± 1.978
0.0GlnCys: 0.0 ± 0.0
1.876GlnAsp: 1.876 ± 0.142
0.938GlnGlu: 0.938 ± 0.776
0.938GlnPhe: 0.938 ± 0.635
1.876GlnGly: 1.876 ± 1.269
1.876GlnHis: 1.876 ± 1.269
0.938GlnIle: 0.938 ± 0.635
0.0GlnLys: 0.0 ± 0.0
1.876GlnLeu: 1.876 ± 0.142
0.0GlnMet: 0.0 ± 0.0
0.938GlnAsn: 0.938 ± 0.776
6.567GlnPro: 6.567 ± 1.201
0.938GlnGln: 0.938 ± 0.776
3.752GlnArg: 3.752 ± 0.283
2.814GlnSer: 2.814 ± 0.918
1.876GlnThr: 1.876 ± 1.553
2.814GlnVal: 2.814 ± 0.493
1.876GlnTrp: 1.876 ± 0.142
0.938GlnTyr: 0.938 ± 0.635
0.0GlnXaa: 0.0 ± 0.0
Arg
0.938ArgAla: 0.938 ± 0.635
1.876ArgCys: 1.876 ± 0.142
2.814ArgAsp: 2.814 ± 0.493
2.814ArgGlu: 2.814 ± 0.493
7.505ArgPhe: 7.505 ± 1.978
0.938ArgGly: 0.938 ± 0.635
0.0ArgHis: 0.0 ± 0.0
3.752ArgIle: 3.752 ± 1.694
1.876ArgLys: 1.876 ± 1.269
7.505ArgLeu: 7.505 ± 2.256
1.876ArgMet: 1.876 ± 0.936
2.814ArgAsn: 2.814 ± 0.493
3.752ArgPro: 3.752 ± 1.128
1.876ArgGln: 1.876 ± 1.553
2.814ArgArg: 2.814 ± 0.493
8.443ArgSer: 8.443 ± 2.89
1.876ArgThr: 1.876 ± 1.553
2.814ArgVal: 2.814 ± 0.918
0.938ArgTrp: 0.938 ± 0.776
1.876ArgTyr: 1.876 ± 0.142
0.0ArgXaa: 0.0 ± 0.0
Ser
4.69SerAla: 4.69 ± 0.351
0.938SerCys: 0.938 ± 0.635
3.752SerAsp: 3.752 ± 1.128
0.938SerGlu: 0.938 ± 0.776
4.69SerPhe: 4.69 ± 1.06
5.629SerGly: 5.629 ± 0.425
3.752SerHis: 3.752 ± 1.128
2.814SerIle: 2.814 ± 1.904
0.938SerLys: 0.938 ± 0.776
7.505SerLeu: 7.505 ± 1.978
2.814SerMet: 2.814 ± 0.918
1.876SerAsn: 1.876 ± 1.553
5.629SerPro: 5.629 ± 1.836
1.876SerGln: 1.876 ± 0.142
5.629SerArg: 5.629 ± 0.425
4.69SerSer: 4.69 ± 1.06
5.629SerThr: 5.629 ± 1.836
5.629SerVal: 5.629 ± 3.247
3.752SerTrp: 3.752 ± 1.128
0.938SerTyr: 0.938 ± 0.635
0.0SerXaa: 0.0 ± 0.0
Thr
8.443ThrAla: 8.443 ± 5.576
0.938ThrCys: 0.938 ± 0.776
2.814ThrAsp: 2.814 ± 0.918
3.752ThrGlu: 3.752 ± 0.283
1.876ThrPhe: 1.876 ± 1.269
4.69ThrGly: 4.69 ± 1.06
0.938ThrHis: 0.938 ± 0.776
6.567ThrIle: 6.567 ± 0.21
2.814ThrLys: 2.814 ± 0.493
6.567ThrLeu: 6.567 ± 2.612
4.69ThrMet: 4.69 ± 0.351
0.0ThrAsn: 0.0 ± 0.0
4.69ThrPro: 4.69 ± 0.351
5.629ThrGln: 5.629 ± 3.247
4.69ThrArg: 4.69 ± 2.471
3.752ThrSer: 3.752 ± 2.539
3.752ThrThr: 3.752 ± 0.283
0.938ThrVal: 0.938 ± 0.776
0.0ThrTrp: 0.0 ± 0.0
0.938ThrTyr: 0.938 ± 0.776
0.0ThrXaa: 0.0 ± 0.0
Val
2.814ValAla: 2.814 ± 2.329
0.938ValCys: 0.938 ± 0.635
0.938ValAsp: 0.938 ± 0.635
0.938ValGlu: 0.938 ± 0.776
2.814ValPhe: 2.814 ± 0.493
1.876ValGly: 1.876 ± 0.142
2.814ValHis: 2.814 ± 0.493
1.876ValIle: 1.876 ± 1.553
1.876ValLys: 1.876 ± 1.269
7.505ValLeu: 7.505 ± 1.978
0.0ValMet: 0.0 ± 0.0
1.876ValAsn: 1.876 ± 1.553
5.629ValPro: 5.629 ± 0.425
2.814ValGln: 2.814 ± 0.493
2.814ValArg: 2.814 ± 0.493
5.629ValSer: 5.629 ± 4.658
0.938ValThr: 0.938 ± 0.776
0.938ValVal: 0.938 ± 0.776
0.0ValTrp: 0.0 ± 0.0
6.567ValTyr: 6.567 ± 0.21
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.938TrpGlu: 0.938 ± 0.635
2.814TrpPhe: 2.814 ± 0.918
0.938TrpGly: 0.938 ± 0.635
0.0TrpHis: 0.0 ± 0.0
1.876TrpIle: 1.876 ± 0.142
0.938TrpLys: 0.938 ± 0.635
0.938TrpLeu: 0.938 ± 0.635
0.0TrpMet: 0.0 ± 0.0
0.938TrpAsn: 0.938 ± 0.776
2.814TrpPro: 2.814 ± 1.904
0.938TrpGln: 0.938 ± 0.635
0.938TrpArg: 0.938 ± 0.635
1.876TrpSer: 1.876 ± 0.142
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.876TrpTyr: 1.876 ± 0.142
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.814TyrAla: 2.814 ± 0.918
0.938TyrCys: 0.938 ± 0.635
2.814TyrAsp: 2.814 ± 0.493
1.876TyrGlu: 1.876 ± 0.142
1.876TyrPhe: 1.876 ± 0.142
1.876TyrGly: 1.876 ± 0.142
1.876TyrHis: 1.876 ± 1.269
2.814TyrIle: 2.814 ± 0.493
0.0TyrLys: 0.0 ± 0.0
3.752TyrLeu: 3.752 ± 1.128
0.938TyrMet: 0.938 ± 0.776
1.876TyrAsn: 1.876 ± 1.269
3.752TyrPro: 3.752 ± 1.128
3.752TyrGln: 3.752 ± 2.539
4.69TyrArg: 4.69 ± 1.06
0.938TyrSer: 0.938 ± 0.776
0.938TyrThr: 0.938 ± 0.635
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.814TyrTyr: 2.814 ± 1.904
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1067 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski