Amino acid dipepetide frequency for Fistulina hepatica ATCC 64428

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.665AlaAla: 8.665 ± 0.07	1.286AlaCys: 1.286 ± 0.018	4.492AlaAsp: 4.492 ± 0.036	4.742AlaGlu: 4.742 ± 0.044	3.455AlaPhe: 3.455 ± 0.033	5.17AlaGly: 5.17 ± 0.042	2.216AlaHis: 2.216 ± 0.027	4.197AlaIle: 4.197 ± 0.037	3.6AlaLys: 3.6 ± 0.034	8.604AlaLeu: 8.604 ± 0.059	1.96AlaMet: 1.96 ± 0.024	2.679AlaAsn: 2.679 ± 0.022	5.121AlaPro: 5.121 ± 0.049	3.257AlaGln: 3.257 ± 0.028	5.644AlaArg: 5.644 ± 0.043	7.775AlaSer: 7.775 ± 0.058	5.314AlaThr: 5.314 ± 0.045	5.801AlaVal: 5.801 ± 0.047	1.202AlaTrp: 1.202 ± 0.019	2.421AlaTyr: 2.421 ± 0.028	0.0AlaXaa: 0.0 ± 0.0
Cys	1.198CysAla: 1.198 ± 0.018	0.284CysCys: 0.284 ± 0.009	0.767CysAsp: 0.767 ± 0.015	0.735CysGlu: 0.735 ± 0.016	0.578CysPhe: 0.578 ± 0.013	0.989CysGly: 0.989 ± 0.019	0.399CysHis: 0.399 ± 0.012	0.822CysIle: 0.822 ± 0.015	0.568CysLys: 0.568 ± 0.013	1.407CysLeu: 1.407 ± 0.021	0.322CysMet: 0.322 ± 0.01	0.484CysAsn: 0.484 ± 0.012	0.863CysPro: 0.863 ± 0.019	0.474CysGln: 0.474 ± 0.012	0.935CysArg: 0.935 ± 0.016	1.071CysSer: 1.071 ± 0.019	0.888CysThr: 0.888 ± 0.015	0.986CysVal: 0.986 ± 0.018	0.205CysTrp: 0.205 ± 0.009	0.39CysTyr: 0.39 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.331AspAla: 5.331 ± 0.04	0.717AspCys: 0.717 ± 0.015	4.765AspAsp: 4.765 ± 0.049	4.356AspGlu: 4.356 ± 0.045	2.28AspPhe: 2.28 ± 0.028	4.109AspGly: 4.109 ± 0.04	1.262AspHis: 1.262 ± 0.017	3.232AspIle: 3.232 ± 0.029	2.148AspLys: 2.148 ± 0.03	5.138AspLeu: 5.138 ± 0.039	1.36AspMet: 1.36 ± 0.021	1.893AspAsn: 1.893 ± 0.021	3.272AspPro: 3.272 ± 0.031	1.53AspGln: 1.53 ± 0.024	2.893AspArg: 2.893 ± 0.035	4.087AspSer: 4.087 ± 0.041	3.187AspThr: 3.187 ± 0.027	4.612AspVal: 4.612 ± 0.035	0.867AspTrp: 0.867 ± 0.015	1.628AspTyr: 1.628 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	4.921GluAla: 4.921 ± 0.047	0.734GluCys: 0.734 ± 0.014	3.978GluAsp: 3.978 ± 0.042	4.507GluGlu: 4.507 ± 0.056	1.902GluPhe: 1.902 ± 0.022	3.279GluGly: 3.279 ± 0.031	1.523GluHis: 1.523 ± 0.024	2.748GluIle: 2.748 ± 0.026	2.8GluLys: 2.8 ± 0.036	5.23GluLeu: 5.23 ± 0.042	1.376GluMet: 1.376 ± 0.021	1.937GluAsn: 1.937 ± 0.023	2.639GluPro: 2.639 ± 0.031	2.17GluGln: 2.17 ± 0.027	4.024GluArg: 4.024 ± 0.045	3.884GluSer: 3.884 ± 0.036	3.053GluThr: 3.053 ± 0.028	3.505GluVal: 3.505 ± 0.033	0.914GluTrp: 0.914 ± 0.016	1.649GluTyr: 1.649 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	3.244PheAla: 3.244 ± 0.029	0.645PheCys: 0.645 ± 0.012	2.407PheAsp: 2.407 ± 0.027	2.087PheGlu: 2.087 ± 0.023	1.642PhePhe: 1.642 ± 0.027	2.607PheGly: 2.607 ± 0.033	0.998PheHis: 0.998 ± 0.017	1.879PheIle: 1.879 ± 0.027	1.438PheLys: 1.438 ± 0.021	3.634PheLeu: 3.634 ± 0.035	0.866PheMet: 0.866 ± 0.016	1.388PheAsn: 1.388 ± 0.019	2.115PhePro: 2.115 ± 0.023	1.246PheGln: 1.246 ± 0.018	2.015PheArg: 2.015 ± 0.027	3.21PheSer: 3.21 ± 0.032	2.237PheThr: 2.237 ± 0.024	2.757PheVal: 2.757 ± 0.03	0.62PheTrp: 0.62 ± 0.015	1.171PheTyr: 1.171 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	4.901GlyAla: 4.901 ± 0.042	0.925GlyCys: 0.925 ± 0.02	3.44GlyAsp: 3.44 ± 0.028	3.165GlyGlu: 3.165 ± 0.032	2.462GlyPhe: 2.462 ± 0.027	4.756GlyGly: 4.756 ± 0.05	1.696GlyHis: 1.696 ± 0.025	3.205GlyIle: 3.205 ± 0.032	2.926GlyLys: 2.926 ± 0.03	5.429GlyLeu: 5.429 ± 0.039	1.498GlyMet: 1.498 ± 0.019	2.104GlyAsn: 2.104 ± 0.025	3.083GlyPro: 3.083 ± 0.035	2.067GlyGln: 2.067 ± 0.025	3.975GlyArg: 3.975 ± 0.036	5.097GlySer: 5.097 ± 0.047	3.828GlyThr: 3.828 ± 0.04	4.273GlyVal: 4.273 ± 0.035	1.046GlyTrp: 1.046 ± 0.019	1.893GlyTyr: 1.893 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.324HisAla: 2.324 ± 0.027	0.405HisCys: 0.405 ± 0.011	1.486HisAsp: 1.486 ± 0.021	1.386HisGlu: 1.386 ± 0.018	1.058HisPhe: 1.058 ± 0.017	1.702HisGly: 1.702 ± 0.02	0.85HisHis: 0.85 ± 0.018	1.463HisIle: 1.463 ± 0.021	0.902HisLys: 0.902 ± 0.015	2.655HisLeu: 2.655 ± 0.028	0.603HisMet: 0.603 ± 0.012	0.855HisAsn: 0.855 ± 0.015	1.868HisPro: 1.868 ± 0.025	0.827HisGln: 0.827 ± 0.016	1.739HisArg: 1.739 ± 0.024	2.036HisSer: 2.036 ± 0.027	1.505HisThr: 1.505 ± 0.018	1.928HisVal: 1.928 ± 0.02	0.365HisTrp: 0.365 ± 0.009	0.728HisTyr: 0.728 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.297IleAla: 4.297 ± 0.037	0.786IleCys: 0.786 ± 0.017	2.999IleAsp: 2.999 ± 0.028	2.717IleGlu: 2.717 ± 0.03	1.926IlePhe: 1.926 ± 0.025	2.835IleGly: 2.835 ± 0.033	1.275IleHis: 1.275 ± 0.017	2.461IleIle: 2.461 ± 0.029	1.915IleLys: 1.915 ± 0.023	4.47IleLeu: 4.47 ± 0.044	1.034IleMet: 1.034 ± 0.016	1.594IleAsn: 1.594 ± 0.02	3.208IlePro: 3.208 ± 0.03	1.714IleGln: 1.714 ± 0.021	2.929IleArg: 2.929 ± 0.028	3.844IleSer: 3.844 ± 0.032	2.631IleThr: 2.631 ± 0.031	3.587IleVal: 3.587 ± 0.035	0.751IleTrp: 0.751 ± 0.017	1.4IleTyr: 1.4 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	3.705LysAla: 3.705 ± 0.034	0.567LysCys: 0.567 ± 0.012	2.306LysAsp: 2.306 ± 0.032	2.665LysGlu: 2.665 ± 0.035	1.324LysPhe: 1.324 ± 0.02	2.402LysGly: 2.402 ± 0.029	1.142LysHis: 1.142 ± 0.017	1.965LysIle: 1.965 ± 0.025	2.575LysLys: 2.575 ± 0.045	3.648LysLeu: 3.648 ± 0.031	0.948LysMet: 0.948 ± 0.018	1.451LysAsn: 1.451 ± 0.021	2.182LysPro: 2.182 ± 0.029	1.537LysGln: 1.537 ± 0.02	3.289LysArg: 3.289 ± 0.035	3.068LysSer: 3.068 ± 0.035	2.437LysThr: 2.437 ± 0.028	2.488LysVal: 2.488 ± 0.03	0.642LysTrp: 0.642 ± 0.014	1.323LysTyr: 1.323 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	8.007LeuAla: 8.007 ± 0.052	1.451LeuCys: 1.451 ± 0.021	5.419LeuAsp: 5.419 ± 0.037	5.262LeuGlu: 5.262 ± 0.045	3.575LeuPhe: 3.575 ± 0.035	5.371LeuGly: 5.371 ± 0.041	2.638LeuHis: 2.638 ± 0.03	3.909LeuIle: 3.909 ± 0.041	3.844LeuLys: 3.844 ± 0.031	8.651LeuLeu: 8.651 ± 0.065	1.833LeuMet: 1.833 ± 0.022	3.092LeuAsn: 3.092 ± 0.032	6.095LeuPro: 6.095 ± 0.045	3.753LeuGln: 3.753 ± 0.035	6.241LeuArg: 6.241 ± 0.049	8.021LeuSer: 8.021 ± 0.052	5.171LeuThr: 5.171 ± 0.041	6.003LeuVal: 6.003 ± 0.045	1.249LeuTrp: 1.249 ± 0.021	2.552LeuTyr: 2.552 ± 0.028	0.0LeuXaa: 0.0 ± 0.0
Met	1.943MetAla: 1.943 ± 0.021	0.311MetCys: 0.311 ± 0.009	1.283MetAsp: 1.283 ± 0.019	1.127MetGlu: 1.127 ± 0.019	0.834MetPhe: 0.834 ± 0.015	1.254MetGly: 1.254 ± 0.019	0.617MetHis: 0.617 ± 0.013	0.978MetIle: 0.978 ± 0.015	0.954MetLys: 0.954 ± 0.016	2.008MetLeu: 2.008 ± 0.028	0.514MetMet: 0.514 ± 0.012	0.764MetAsn: 0.764 ± 0.014	1.473MetPro: 1.473 ± 0.023	0.862MetGln: 0.862 ± 0.017	1.405MetArg: 1.405 ± 0.018	2.211MetSer: 2.211 ± 0.025	1.364MetThr: 1.364 ± 0.019	1.293MetVal: 1.293 ± 0.021	0.297MetTrp: 0.297 ± 0.011	0.633MetTyr: 0.633 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.185AsnAla: 3.185 ± 0.032	0.435AsnCys: 0.435 ± 0.011	1.936AsnAsp: 1.936 ± 0.022	1.867AsnGlu: 1.867 ± 0.024	1.27AsnPhe: 1.27 ± 0.019	2.47AsnGly: 2.47 ± 0.029	0.77AsnHis: 0.77 ± 0.014	1.885AsnIle: 1.885 ± 0.023	1.313AsnLys: 1.313 ± 0.017	2.9AsnLeu: 2.9 ± 0.031	0.795AsnMet: 0.795 ± 0.014	1.235AsnAsn: 1.235 ± 0.022	2.028AsnPro: 2.028 ± 0.022	0.99AsnGln: 0.99 ± 0.018	1.707AsnArg: 1.707 ± 0.022	2.465AsnSer: 2.465 ± 0.028	2.037AsnThr: 2.037 ± 0.025	2.568AsnVal: 2.568 ± 0.026	0.485AsnTrp: 0.485 ± 0.012	0.935AsnTyr: 0.935 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.456ProAla: 5.456 ± 0.049	0.675ProCys: 0.675 ± 0.017	3.361ProAsp: 3.361 ± 0.034	3.483ProGlu: 3.483 ± 0.034	2.248ProPhe: 2.248 ± 0.026	3.487ProGly: 3.487 ± 0.035	1.658ProHis: 1.658 ± 0.021	2.546ProIle: 2.546 ± 0.025	2.146ProLys: 2.146 ± 0.027	5.293ProLeu: 5.293 ± 0.039	1.154ProMet: 1.154 ± 0.02	1.904ProAsn: 1.904 ± 0.024	5.84ProPro: 5.84 ± 0.077	2.226ProGln: 2.226 ± 0.026	3.732ProArg: 3.732 ± 0.037	6.586ProSer: 6.586 ± 0.057	4.084ProThr: 4.084 ± 0.038	4.168ProVal: 4.168 ± 0.04	0.778ProTrp: 0.778 ± 0.015	1.626ProTyr: 1.626 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.16GlnAla: 3.16 ± 0.03	0.519GlnCys: 0.519 ± 0.013	1.868GlnAsp: 1.868 ± 0.024	2.03GlnGlu: 2.03 ± 0.026	1.245GlnPhe: 1.245 ± 0.016	1.919GlnGly: 1.919 ± 0.024	1.034GlnHis: 1.034 ± 0.017	1.72GlnIle: 1.72 ± 0.023	1.493GlnLys: 1.493 ± 0.023	3.425GlnLeu: 3.425 ± 0.034	0.877GlnMet: 0.877 ± 0.015	1.204GlnAsn: 1.204 ± 0.018	2.171GlnPro: 2.171 ± 0.026	1.901GlnGln: 1.901 ± 0.05	2.58GlnArg: 2.58 ± 0.028	2.772GlnSer: 2.772 ± 0.03	2.121GlnThr: 2.121 ± 0.025	2.176GlnVal: 2.176 ± 0.026	0.563GlnTrp: 0.563 ± 0.012	1.061GlnTyr: 1.061 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.389ArgAla: 5.389 ± 0.042	0.927ArgCys: 0.927 ± 0.015	3.508ArgAsp: 3.508 ± 0.03	3.727ArgGlu: 3.727 ± 0.037	2.251ArgPhe: 2.251 ± 0.028	3.588ArgGly: 3.588 ± 0.037	1.812ArgHis: 1.812 ± 0.022	3.078ArgIle: 3.078 ± 0.03	3.194ArgLys: 3.194 ± 0.038	6.003ArgLeu: 6.003 ± 0.048	1.408ArgMet: 1.408 ± 0.02	2.081ArgAsn: 2.081 ± 0.023	3.656ArgPro: 3.656 ± 0.037	2.486ArgGln: 2.486 ± 0.025	5.592ArgArg: 5.592 ± 0.057	5.003ArgSer: 5.003 ± 0.044	3.654ArgThr: 3.654 ± 0.032	3.946ArgVal: 3.946 ± 0.031	1.015ArgTrp: 1.015 ± 0.016	1.763ArgTyr: 1.763 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	7.311SerAla: 7.311 ± 0.059	1.095SerCys: 1.095 ± 0.019	4.627SerAsp: 4.627 ± 0.044	3.925SerGlu: 3.925 ± 0.036	3.209SerPhe: 3.209 ± 0.034	5.384SerGly: 5.384 ± 0.047	2.171SerHis: 2.171 ± 0.028	3.858SerIle: 3.858 ± 0.041	3.177SerLys: 3.177 ± 0.031	7.591SerLeu: 7.591 ± 0.049	1.847SerMet: 1.847 ± 0.02	2.731SerAsn: 2.731 ± 0.032	5.854SerPro: 5.854 ± 0.059	2.892SerGln: 2.892 ± 0.03	5.206SerArg: 5.206 ± 0.049	9.845SerSer: 9.845 ± 0.103	5.972SerThr: 5.972 ± 0.059	5.498SerVal: 5.498 ± 0.053	1.054SerTrp: 1.054 ± 0.016	2.103SerTyr: 2.103 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	5.27ThrAla: 5.27 ± 0.041	0.864ThrCys: 0.864 ± 0.017	3.024ThrAsp: 3.024 ± 0.03	2.776ThrGlu: 2.776 ± 0.03	2.433ThrPhe: 2.433 ± 0.026	3.75ThrGly: 3.75 ± 0.034	1.548ThrHis: 1.548 ± 0.021	3.037ThrIle: 3.037 ± 0.032	2.176ThrLys: 2.176 ± 0.029	5.649ThrLeu: 5.649 ± 0.041	1.264ThrMet: 1.264 ± 0.019	1.93ThrAsn: 1.93 ± 0.024	4.361ThrPro: 4.361 ± 0.043	1.907ThrGln: 1.907 ± 0.022	3.427ThrArg: 3.427 ± 0.028	5.86ThrSer: 5.86 ± 0.065	4.132ThrThr: 4.132 ± 0.053	4.121ThrVal: 4.121 ± 0.044	0.859ThrTrp: 0.859 ± 0.016	1.728ThrTyr: 1.728 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	5.791ValAla: 5.791 ± 0.045	1.043ValCys: 1.043 ± 0.018	4.316ValAsp: 4.316 ± 0.035	3.915ValGlu: 3.915 ± 0.039	2.734ValPhe: 2.734 ± 0.028	3.933ValGly: 3.933 ± 0.035	1.865ValHis: 1.865 ± 0.023	3.12ValIle: 3.12 ± 0.035	2.742ValLys: 2.742 ± 0.03	6.444ValLeu: 6.444 ± 0.053	1.439ValMet: 1.439 ± 0.023	2.213ValAsn: 2.213 ± 0.025	4.353ValPro: 4.353 ± 0.04	2.522ValGln: 2.522 ± 0.027	3.995ValArg: 3.995 ± 0.035	5.33ValSer: 5.33 ± 0.045	3.776ValThr: 3.776 ± 0.043	5.044ValVal: 5.044 ± 0.043	0.987ValTrp: 0.987 ± 0.02	1.977ValTyr: 1.977 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.152TrpAla: 1.152 ± 0.02	0.249TrpCys: 0.249 ± 0.008	0.889TrpAsp: 0.889 ± 0.018	0.802TrpGlu: 0.802 ± 0.016	0.549TrpPhe: 0.549 ± 0.013	0.847TrpGly: 0.847 ± 0.018	0.418TrpHis: 0.418 ± 0.009	0.752TrpIle: 0.752 ± 0.015	0.741TrpLys: 0.741 ± 0.014	1.293TrpLeu: 1.293 ± 0.021	0.372TrpMet: 0.372 ± 0.01	0.595TrpAsn: 0.595 ± 0.013	0.666TrpPro: 0.666 ± 0.015	0.534TrpGln: 0.534 ± 0.011	1.038TrpArg: 1.038 ± 0.018	1.134TrpSer: 1.134 ± 0.019	1.004TrpThr: 1.004 ± 0.019	0.855TrpVal: 0.855 ± 0.017	0.29TrpTrp: 0.29 ± 0.009	0.442TrpTyr: 0.442 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.353TyrAla: 2.353 ± 0.029	0.449TyrCys: 0.449 ± 0.012	1.798TyrAsp: 1.798 ± 0.022	1.5TyrGlu: 1.5 ± 0.021	1.229TyrPhe: 1.229 ± 0.02	1.916TyrGly: 1.916 ± 0.03	0.793TyrHis: 0.793 ± 0.014	1.519TyrIle: 1.519 ± 0.019	1.014TyrLys: 1.014 ± 0.017	2.667TyrLeu: 2.667 ± 0.03	0.652TyrMet: 0.652 ± 0.013	1.144TyrAsn: 1.144 ± 0.017	1.599TyrPro: 1.599 ± 0.024	0.947TyrGln: 0.947 ± 0.016	1.714TyrArg: 1.714 ± 0.025	2.05TyrSer: 2.05 ± 0.026	1.72TyrThr: 1.72 ± 0.024	1.928TyrVal: 1.928 ± 0.024	0.432TyrTrp: 0.432 ± 0.01	0.927TyrTyr: 0.927 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9322 proteins (3775801 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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