Amino acid dipepetide frequency for Victorian trout aquabirnavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.78AlaAla: 10.78 ± 1.752
0.0AlaCys: 0.0 ± 0.0
5.133AlaAsp: 5.133 ± 0.411
3.593AlaGlu: 3.593 ± 2.235
2.567AlaPhe: 2.567 ± 0.498
5.133AlaGly: 5.133 ± 1.002
1.027AlaHis: 1.027 ± 0.763
3.593AlaIle: 3.593 ± 0.815
4.107AlaLys: 4.107 ± 0.695
5.133AlaLeu: 5.133 ± 1.332
2.567AlaMet: 2.567 ± 0.666
3.593AlaAsn: 3.593 ± 0.625
6.674AlaPro: 6.674 ± 1.389
2.053AlaGln: 2.053 ± 0.932
1.54AlaArg: 1.54 ± 0.408
6.674AlaSer: 6.674 ± 2.617
6.674AlaThr: 6.674 ± 1.085
4.62AlaVal: 4.62 ± 0.972
0.513AlaTrp: 0.513 ± 0.382
1.54AlaTyr: 1.54 ± 0.533
0.0AlaXaa: 0.0 ± 0.0
Cys
0.513CysAla: 0.513 ± 1.14
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.513CysPhe: 0.513 ± 0.382
1.027CysGly: 1.027 ± 0.174
0.0CysHis: 0.0 ± 0.0
0.513CysIle: 0.513 ± 0.43
0.0CysLys: 0.0 ± 0.0
0.513CysLeu: 0.513 ± 1.14
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.027CysGln: 1.027 ± 0.763
0.0CysArg: 0.0 ± 0.0
1.027CysSer: 1.027 ± 2.28
1.027CysThr: 1.027 ± 0.174
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.053AspAla: 2.053 ± 0.771
0.0AspCys: 0.0 ± 0.0
3.08AspAsp: 3.08 ± 0.521
3.08AspGlu: 3.08 ± 0.817
3.593AspPhe: 3.593 ± 0.625
3.593AspGly: 3.593 ± 1.893
0.513AspHis: 0.513 ± 0.43
7.187AspIle: 7.187 ± 2.37
3.593AspLys: 3.593 ± 0.815
7.7AspLeu: 7.7 ± 0.392
0.0AspMet: 0.0 ± 0.0
4.62AspAsn: 4.62 ± 0.769
4.62AspPro: 4.62 ± 0.532
3.593AspGln: 3.593 ± 1.174
1.027AspArg: 1.027 ± 0.86
3.08AspSer: 3.08 ± 1.066
3.08AspThr: 3.08 ± 0.521
2.567AspVal: 2.567 ± 0.666
1.027AspTrp: 1.027 ± 0.86
1.027AspTyr: 1.027 ± 0.763
0.0AspXaa: 0.0 ± 0.0
Glu
5.647GluAla: 5.647 ± 2.692
0.0GluCys: 0.0 ± 0.0
3.593GluAsp: 3.593 ± 0.625
5.133GluGlu: 5.133 ± 1.002
2.567GluPhe: 2.567 ± 1.237
3.08GluGly: 3.08 ± 1.524
1.027GluHis: 1.027 ± 1.105
4.62GluIle: 4.62 ± 2.416
4.107GluLys: 4.107 ± 1.194
5.647GluLeu: 5.647 ± 1.298
0.513GluMet: 0.513 ± 0.43
3.593GluAsn: 3.593 ± 0.815
1.54GluPro: 1.54 ± 0.977
1.54GluGln: 1.54 ± 0.533
3.593GluArg: 3.593 ± 0.668
3.08GluSer: 3.08 ± 2.037
7.187GluThr: 7.187 ± 1.558
5.647GluVal: 5.647 ± 1.298
2.053GluTrp: 2.053 ± 0.932
1.027GluTyr: 1.027 ± 0.763
0.0GluXaa: 0.0 ± 0.0
Phe
1.54PheAla: 1.54 ± 0.408
0.0PheCys: 0.0 ± 0.0
1.54PheAsp: 1.54 ± 1.145
2.053PheGlu: 2.053 ± 1.526
0.513PhePhe: 0.513 ± 0.43
2.053PheGly: 2.053 ± 0.347
1.027PheHis: 1.027 ± 0.86
1.027PheIle: 1.027 ± 0.174
1.54PheLys: 1.54 ± 0.408
2.567PheLeu: 2.567 ± 1.379
0.513PheMet: 0.513 ± 0.43
2.053PheAsn: 2.053 ± 0.347
2.053PhePro: 2.053 ± 0.347
1.027PheGln: 1.027 ± 0.763
0.513PheArg: 0.513 ± 0.43
3.08PheSer: 3.08 ± 0.817
2.053PheThr: 2.053 ± 0.771
0.513PheVal: 0.513 ± 0.43
0.513PheTrp: 0.513 ± 0.43
1.54PheTyr: 1.54 ± 0.977
0.0PheXaa: 0.0 ± 0.0
Gly
5.647GlyAla: 5.647 ± 2.67
0.513GlyCys: 0.513 ± 0.382
5.133GlyAsp: 5.133 ± 0.411
5.647GlyGlu: 5.647 ± 1.298
1.54GlyPhe: 1.54 ± 0.533
3.593GlyGly: 3.593 ± 0.625
0.0GlyHis: 0.0 ± 0.0
3.08GlyIle: 3.08 ± 0.918
4.107GlyLys: 4.107 ± 1.905
5.647GlyLeu: 5.647 ± 1.332
1.54GlyMet: 1.54 ± 0.408
3.593GlyAsn: 3.593 ± 1.174
5.133GlyPro: 5.133 ± 2.542
1.54GlyGln: 1.54 ± 0.533
3.593GlyArg: 3.593 ± 1.534
5.647GlySer: 5.647 ± 0.424
2.567GlyThr: 2.567 ± 0.666
5.133GlyVal: 5.133 ± 3.046
2.053GlyTrp: 2.053 ± 0.953
2.053GlyTyr: 2.053 ± 0.953
0.0GlyXaa: 0.0 ± 0.0
His
0.513HisAla: 0.513 ± 0.382
0.0HisCys: 0.0 ± 0.0
1.027HisAsp: 1.027 ± 0.86
1.54HisGlu: 1.54 ± 0.977
0.513HisPhe: 0.513 ± 0.382
1.027HisGly: 1.027 ± 0.174
0.0HisHis: 0.0 ± 0.0
0.513HisIle: 0.513 ± 0.382
1.027HisLys: 1.027 ± 1.155
2.053HisLeu: 2.053 ± 1.029
1.027HisMet: 1.027 ± 0.86
0.513HisAsn: 0.513 ± 1.14
0.513HisPro: 0.513 ± 1.14
1.027HisGln: 1.027 ± 0.763
1.027HisArg: 1.027 ± 0.763
1.027HisSer: 1.027 ± 1.105
1.027HisThr: 1.027 ± 0.763
0.513HisVal: 0.513 ± 1.14
0.0HisTrp: 0.0 ± 0.0
1.027HisTyr: 1.027 ± 1.105
0.0HisXaa: 0.0 ± 0.0
Ile
2.567IleAla: 2.567 ± 1.379
0.513IleCys: 0.513 ± 0.382
2.567IleAsp: 2.567 ± 0.666
2.053IleGlu: 2.053 ± 0.347
1.54IlePhe: 1.54 ± 0.408
3.593IleGly: 3.593 ± 1.904
0.513IleHis: 0.513 ± 1.14
2.567IleIle: 2.567 ± 0.666
1.54IleLys: 1.54 ± 1.145
4.107IleLeu: 4.107 ± 0.695
0.513IleMet: 0.513 ± 0.382
2.567IleAsn: 2.567 ± 0.666
5.647IlePro: 5.647 ± 1.332
2.567IleGln: 2.567 ± 2.042
4.62IleArg: 4.62 ± 1.701
2.567IleSer: 2.567 ± 1.653
4.62IleThr: 4.62 ± 0.769
3.08IleVal: 3.08 ± 0.817
0.513IleTrp: 0.513 ± 0.43
2.053IleTyr: 2.053 ± 0.347
0.0IleXaa: 0.0 ± 0.0
Lys
6.16LysAla: 6.16 ± 1.478
0.0LysCys: 0.0 ± 0.0
3.08LysAsp: 3.08 ± 1.806
2.053LysGlu: 2.053 ± 0.771
2.053LysPhe: 2.053 ± 1.526
4.62LysGly: 4.62 ± 1.599
2.053LysHis: 2.053 ± 1.029
3.08LysIle: 3.08 ± 0.521
3.08LysLys: 3.08 ± 1.066
3.593LysLeu: 3.593 ± 0.815
1.54LysMet: 1.54 ± 1.145
4.107LysAsn: 4.107 ± 0.584
4.107LysPro: 4.107 ± 0.695
2.053LysGln: 2.053 ± 1.029
2.567LysArg: 2.567 ± 1.379
3.593LysSer: 3.593 ± 2.654
5.133LysThr: 5.133 ± 2.286
1.027LysVal: 1.027 ± 0.763
0.513LysTrp: 0.513 ± 1.14
2.567LysTyr: 2.567 ± 0.498
0.0LysXaa: 0.0 ± 0.0
Leu
7.7LeuAla: 7.7 ± 1.465
0.0LeuCys: 0.0 ± 0.0
5.647LeuAsp: 5.647 ± 1.725
8.727LeuGlu: 8.727 ± 2.829
1.027LeuPhe: 1.027 ± 0.174
3.08LeuGly: 3.08 ± 0.817
0.0LeuHis: 0.0 ± 0.0
5.133LeuIle: 5.133 ± 0.997
8.214LeuLys: 8.214 ± 1.195
10.78LeuLeu: 10.78 ± 2.639
3.593LeuMet: 3.593 ± 0.815
3.593LeuAsn: 3.593 ± 0.625
8.727LeuPro: 8.727 ± 1.952
3.593LeuGln: 3.593 ± 0.668
6.674LeuArg: 6.674 ± 3.251
4.62LeuSer: 4.62 ± 1.225
4.62LeuThr: 4.62 ± 0.972
4.107LeuVal: 4.107 ± 1.121
0.0LeuTrp: 0.0 ± 0.0
1.027LeuTyr: 1.027 ± 0.174
0.0LeuXaa: 0.0 ± 0.0
Met
1.027MetAla: 1.027 ± 0.763
0.0MetCys: 0.0 ± 0.0
3.08MetAsp: 3.08 ± 0.817
0.513MetGlu: 0.513 ± 0.43
0.513MetPhe: 0.513 ± 0.43
1.027MetGly: 1.027 ± 0.763
0.0MetHis: 0.0 ± 0.0
1.54MetIle: 1.54 ± 0.408
2.053MetLys: 2.053 ± 0.953
1.027MetLeu: 1.027 ± 0.174
0.513MetMet: 0.513 ± 0.43
3.08MetAsn: 3.08 ± 0.918
0.0MetPro: 0.0 ± 0.0
1.027MetGln: 1.027 ± 0.174
1.027MetArg: 1.027 ± 0.763
3.08MetSer: 3.08 ± 1.066
1.54MetThr: 1.54 ± 0.533
3.593MetVal: 3.593 ± 1.483
0.0MetTrp: 0.0 ± 0.0
0.513MetTyr: 0.513 ± 0.43
0.0MetXaa: 0.0 ± 0.0
Asn
3.593AsnAla: 3.593 ± 0.625
0.513AsnCys: 0.513 ± 0.43
4.107AsnAsp: 4.107 ± 1.542
1.54AsnGlu: 1.54 ± 0.533
1.54AsnPhe: 1.54 ± 0.408
3.08AsnGly: 3.08 ± 2.289
1.027AsnHis: 1.027 ± 1.155
2.053AsnIle: 2.053 ± 0.953
2.567AsnLys: 2.567 ± 1.379
4.107AsnLeu: 4.107 ± 0.83
2.053AsnMet: 2.053 ± 0.371
3.593AsnAsn: 3.593 ± 0.815
7.7AsnPro: 7.7 ± 2.665
3.593AsnGln: 3.593 ± 1.904
2.053AsnArg: 2.053 ± 2.117
2.567AsnSer: 2.567 ± 1.146
2.567AsnThr: 2.567 ± 0.666
1.54AsnVal: 1.54 ± 0.533
1.027AsnTrp: 1.027 ± 1.155
2.567AsnTyr: 2.567 ± 1.908
0.0AsnXaa: 0.0 ± 0.0
Pro
4.107ProAla: 4.107 ± 1.542
0.0ProCys: 0.0 ± 0.0
4.107ProAsp: 4.107 ± 0.584
7.187ProGlu: 7.187 ± 2.502
1.54ProPhe: 1.54 ± 0.533
6.16ProGly: 6.16 ± 1.683
1.027ProHis: 1.027 ± 0.174
2.567ProIle: 2.567 ± 1.146
5.647ProLys: 5.647 ± 3.185
3.593ProLeu: 3.593 ± 0.815
1.027ProMet: 1.027 ± 0.174
3.08ProAsn: 3.08 ± 0.817
3.593ProPro: 3.593 ± 1.174
3.593ProGln: 3.593 ± 0.625
5.647ProArg: 5.647 ± 1.129
3.593ProSer: 3.593 ± 0.815
5.133ProThr: 5.133 ± 0.868
5.647ProVal: 5.647 ± 0.588
0.513ProTrp: 0.513 ± 1.14
1.54ProTyr: 1.54 ± 0.533
0.0ProXaa: 0.0 ± 0.0
Gln
2.567GlnAla: 2.567 ± 0.666
0.0GlnCys: 0.0 ± 0.0
2.567GlnAsp: 2.567 ± 1.146
2.053GlnGlu: 2.053 ± 1.526
2.053GlnPhe: 2.053 ± 0.771
2.053GlnGly: 2.053 ± 0.771
1.027GlnHis: 1.027 ± 0.174
0.513GlnIle: 0.513 ± 0.43
1.027GlnLys: 1.027 ± 0.174
4.62GlnLeu: 4.62 ± 0.532
2.567GlnMet: 2.567 ± 0.666
1.54GlnAsn: 1.54 ± 0.408
1.54GlnPro: 1.54 ± 0.977
2.053GlnGln: 2.053 ± 0.347
1.54GlnArg: 1.54 ± 1.318
3.08GlnSer: 3.08 ± 1.252
4.107GlnThr: 4.107 ± 0.894
2.053GlnVal: 2.053 ± 1.029
0.513GlnTrp: 0.513 ± 0.382
1.027GlnTyr: 1.027 ± 0.86
0.0GlnXaa: 0.0 ± 0.0
Arg
2.567ArgAla: 2.567 ± 1.146
0.513ArgCys: 0.513 ± 0.382
4.107ArgAsp: 4.107 ± 1.795
5.133ArgGlu: 5.133 ± 3.208
1.027ArgPhe: 1.027 ± 0.174
3.08ArgGly: 3.08 ± 1.252
2.053ArgHis: 2.053 ± 2.21
2.053ArgIle: 2.053 ± 0.771
4.107ArgLys: 4.107 ± 1.863
6.674ArgLeu: 6.674 ± 0.474
1.027ArgMet: 1.027 ± 0.174
2.053ArgAsn: 2.053 ± 1.584
3.593ArgPro: 3.593 ± 0.668
3.08ArgGln: 3.08 ± 1.066
4.107ArgArg: 4.107 ± 1.121
1.54ArgSer: 1.54 ± 0.977
3.08ArgThr: 3.08 ± 1.524
2.053ArgVal: 2.053 ± 0.953
1.027ArgTrp: 1.027 ± 0.174
3.593ArgTyr: 3.593 ± 0.625
0.0ArgXaa: 0.0 ± 0.0
Ser
4.62SerAla: 4.62 ± 3.093
2.053SerCys: 2.053 ± 1.029
3.08SerAsp: 3.08 ± 1.066
3.08SerGlu: 3.08 ± 2.18
1.027SerPhe: 1.027 ± 0.174
7.7SerGly: 7.7 ± 1.976
2.567SerHis: 2.567 ± 1.653
4.62SerIle: 4.62 ± 1.426
1.54SerLys: 1.54 ± 0.977
6.674SerLeu: 6.674 ± 1.254
1.54SerMet: 1.54 ± 0.533
2.053SerAsn: 2.053 ± 0.932
3.593SerPro: 3.593 ± 2.235
1.027SerGln: 1.027 ± 0.174
3.593SerArg: 3.593 ± 1.534
5.647SerSer: 5.647 ± 1.531
4.107SerThr: 4.107 ± 0.695
3.593SerVal: 3.593 ± 2.569
2.567SerTrp: 2.567 ± 2.042
2.567SerTyr: 2.567 ± 0.498
0.0SerXaa: 0.0 ± 0.0
Thr
6.674ThrAla: 6.674 ± 1.389
0.0ThrCys: 0.0 ± 0.0
2.567ThrAsp: 2.567 ± 0.666
2.567ThrGlu: 2.567 ± 1.146
2.567ThrPhe: 2.567 ± 1.379
6.674ThrGly: 6.674 ± 1.298
1.027ThrHis: 1.027 ± 1.155
3.08ThrIle: 3.08 ± 0.521
4.107ThrLys: 4.107 ± 0.894
7.187ThrLeu: 7.187 ± 2.257
1.027ThrMet: 1.027 ± 0.174
4.62ThrAsn: 4.62 ± 0.769
5.133ThrPro: 5.133 ± 1.332
2.567ThrGln: 2.567 ± 0.666
5.133ThrArg: 5.133 ± 1.002
5.133ThrSer: 5.133 ± 1.579
3.08ThrThr: 3.08 ± 0.521
4.62ThrVal: 4.62 ± 1.225
1.027ThrTrp: 1.027 ± 0.86
1.54ThrTyr: 1.54 ± 0.533
0.0ThrXaa: 0.0 ± 0.0
Val
4.62ValAla: 4.62 ± 1.426
1.027ValCys: 1.027 ± 1.105
2.567ValAsp: 2.567 ± 0.666
5.647ValGlu: 5.647 ± 0.424
1.027ValPhe: 1.027 ± 0.763
2.567ValGly: 2.567 ± 1.379
0.513ValHis: 0.513 ± 0.382
1.54ValIle: 1.54 ± 1.198
3.08ValLys: 3.08 ± 1.066
4.62ValLeu: 4.62 ± 1.225
2.567ValMet: 2.567 ± 0.806
2.053ValAsn: 2.053 ± 0.771
2.567ValPro: 2.567 ± 0.498
1.027ValGln: 1.027 ± 0.174
4.62ValArg: 4.62 ± 1.426
4.107ValSer: 4.107 ± 0.894
5.133ValThr: 5.133 ± 1.579
4.107ValVal: 4.107 ± 0.894
1.54ValTrp: 1.54 ± 0.408
1.027ValTyr: 1.027 ± 0.174
0.0ValXaa: 0.0 ± 0.0
Trp
2.053TrpAla: 2.053 ± 1.584
1.027TrpCys: 1.027 ± 2.28
0.513TrpAsp: 0.513 ± 0.43
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.027TrpGly: 1.027 ± 0.763
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.54TrpLeu: 1.54 ± 0.977
0.0TrpMet: 0.0 ± 0.0
1.54TrpAsn: 1.54 ± 0.533
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.54TrpArg: 1.54 ± 0.408
2.567TrpSer: 2.567 ± 2.105
1.54TrpThr: 1.54 ± 0.408
1.027TrpVal: 1.027 ± 0.174
0.0TrpTrp: 0.0 ± 0.0
1.027TrpTyr: 1.027 ± 0.86
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.567TyrAla: 2.567 ± 2.042
0.0TyrCys: 0.0 ± 0.0
1.54TyrAsp: 1.54 ± 1.145
3.593TyrGlu: 3.593 ± 1.904
0.0TyrPhe: 0.0 ± 0.0
3.593TyrGly: 3.593 ± 0.815
0.513TyrHis: 0.513 ± 0.382
1.027TyrIle: 1.027 ± 0.86
1.54TyrLys: 1.54 ± 0.408
3.08TyrLeu: 3.08 ± 1.066
0.513TyrMet: 0.513 ± 0.382
1.54TyrAsn: 1.54 ± 0.408
2.567TyrPro: 2.567 ± 1.379
0.513TyrGln: 0.513 ± 0.43
2.053TyrArg: 2.053 ± 0.771
1.54TyrSer: 1.54 ± 1.289
2.053TyrThr: 2.053 ± 0.953
1.027TyrVal: 1.027 ± 0.763
0.0TyrTrp: 0.0 ± 0.0
1.54TyrTyr: 1.54 ± 0.533
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1949 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski