Amino acid dipepetide frequency for Beihai tombus-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.778AlaAla: 4.778 ± 1.036
0.683AlaCys: 0.683 ± 0.451
5.461AlaAsp: 5.461 ± 1.981
0.683AlaGlu: 0.683 ± 0.719
2.048AlaPhe: 2.048 ± 0.848
2.048AlaGly: 2.048 ± 0.848
0.683AlaHis: 0.683 ± 0.451
8.191AlaIle: 8.191 ± 3.182
7.509AlaLys: 7.509 ± 2.117
10.239AlaLeu: 10.239 ± 1.015
1.365AlaMet: 1.365 ± 1.439
2.73AlaAsn: 2.73 ± 0.305
2.048AlaPro: 2.048 ± 0.178
2.73AlaGln: 2.73 ± 1.261
4.096AlaArg: 4.096 ± 0.355
4.096AlaSer: 4.096 ± 0.805
4.096AlaThr: 4.096 ± 2.077
6.143AlaVal: 6.143 ± 2.668
0.683AlaTrp: 0.683 ± 0.451
0.683AlaTyr: 0.683 ± 0.451
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.365CysCys: 1.365 ± 0.578
0.683CysAsp: 0.683 ± 0.451
0.683CysGlu: 0.683 ± 0.451
1.365CysPhe: 1.365 ± 0.614
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.365CysIle: 1.365 ± 1.194
0.0CysLys: 0.0 ± 0.0
2.73CysLeu: 2.73 ± 1.494
0.0CysMet: 0.0 ± 0.0
2.048CysAsn: 2.048 ± 2.158
0.683CysPro: 0.683 ± 0.451
2.048CysGln: 2.048 ± 0.178
0.683CysArg: 0.683 ± 0.597
2.048CysSer: 2.048 ± 1.084
1.365CysThr: 1.365 ± 0.578
0.683CysVal: 0.683 ± 0.597
0.0CysTrp: 0.0 ± 0.0
1.365CysTyr: 1.365 ± 1.194
0.0CysXaa: 0.0 ± 0.0
Asp
4.096AspAla: 4.096 ± 1.373
2.048AspCys: 2.048 ± 0.974
3.413AspAsp: 3.413 ± 1.591
2.048AspGlu: 2.048 ± 0.828
4.096AspPhe: 4.096 ± 0.805
3.413AspGly: 3.413 ± 0.749
2.048AspHis: 2.048 ± 0.178
1.365AspIle: 1.365 ± 0.902
1.365AspLys: 1.365 ± 0.614
4.778AspLeu: 4.778 ± 0.68
2.73AspMet: 2.73 ± 0.874
2.73AspAsn: 2.73 ± 1.175
3.413AspPro: 3.413 ± 1.379
2.048AspGln: 2.048 ± 0.848
3.413AspArg: 3.413 ± 0.709
3.413AspSer: 3.413 ± 2.235
0.683AspThr: 0.683 ± 0.597
2.73AspVal: 2.73 ± 0.614
0.0AspTrp: 0.0 ± 0.0
2.048AspTyr: 2.048 ± 0.848
0.0AspXaa: 0.0 ± 0.0
Glu
5.461GluAla: 5.461 ± 0.394
0.0GluCys: 0.0 ± 0.0
0.683GluAsp: 0.683 ± 0.719
5.461GluGlu: 5.461 ± 1.748
4.778GluPhe: 4.778 ± 0.214
3.413GluGly: 3.413 ± 1.632
0.683GluHis: 0.683 ± 0.597
3.413GluIle: 3.413 ± 0.783
4.778GluLys: 4.778 ± 1.036
3.413GluLeu: 3.413 ± 1.379
1.365GluMet: 1.365 ± 0.631
2.048GluAsn: 2.048 ± 1.197
1.365GluPro: 1.365 ± 0.614
0.0GluGln: 0.0 ± 0.0
2.048GluArg: 2.048 ± 0.974
0.683GluSer: 0.683 ± 0.597
2.73GluThr: 2.73 ± 1.175
4.778GluVal: 4.778 ± 2.497
2.048GluTrp: 2.048 ± 0.828
2.048GluTyr: 2.048 ± 1.79
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.365PheCys: 1.365 ± 0.578
2.048PheAsp: 2.048 ± 1.084
2.73PheGlu: 2.73 ± 0.614
0.0PhePhe: 0.0 ± 0.0
2.048PheGly: 2.048 ± 1.084
0.0PheHis: 0.0 ± 0.0
0.683PheIle: 0.683 ± 0.597
2.73PheLys: 2.73 ± 1.261
3.413PheLeu: 3.413 ± 1.646
2.048PheMet: 2.048 ± 0.178
2.048PheAsn: 2.048 ± 0.848
2.73PhePro: 2.73 ± 1.175
1.365PheGln: 1.365 ± 0.578
2.73PheArg: 2.73 ± 1.877
4.096PheSer: 4.096 ± 1.733
1.365PheThr: 1.365 ± 0.631
3.413PheVal: 3.413 ± 2.256
0.0PheTrp: 0.0 ± 0.0
2.73PheTyr: 2.73 ± 0.874
0.0PheXaa: 0.0 ± 0.0
Gly
3.413GlyAla: 3.413 ± 1.646
2.048GlyCys: 2.048 ± 1.084
4.096GlyAsp: 4.096 ± 1.022
2.73GlyGlu: 2.73 ± 1.494
1.365GlyPhe: 1.365 ± 0.902
2.73GlyGly: 2.73 ± 1.155
0.683GlyHis: 0.683 ± 0.597
4.096GlyIle: 4.096 ± 1.695
6.826GlyLys: 6.826 ± 2.802
3.413GlyLeu: 3.413 ± 0.462
1.365GlyMet: 1.365 ± 1.194
6.826GlyAsn: 6.826 ± 3.002
2.73GlyPro: 2.73 ± 1.229
1.365GlyGln: 1.365 ± 1.439
1.365GlyArg: 1.365 ± 0.902
0.0GlySer: 0.0 ± 0.0
4.096GlyThr: 4.096 ± 1.199
4.096GlyVal: 4.096 ± 2.077
2.048GlyTrp: 2.048 ± 0.848
2.73GlyTyr: 2.73 ± 1.972
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.683HisCys: 0.683 ± 0.451
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.683HisPhe: 0.683 ± 0.597
1.365HisGly: 1.365 ± 0.614
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.683HisLys: 0.683 ± 0.597
2.048HisLeu: 2.048 ± 0.178
0.0HisMet: 0.0 ± 0.473
1.365HisAsn: 1.365 ± 0.902
1.365HisPro: 1.365 ± 0.614
0.683HisGln: 0.683 ± 0.451
0.0HisArg: 0.0 ± 0.0
4.778HisSer: 4.778 ± 2.385
0.683HisThr: 0.683 ± 0.451
0.683HisVal: 0.683 ± 0.719
0.683HisTrp: 0.683 ± 0.719
2.048HisTyr: 2.048 ± 1.084
0.0HisXaa: 0.0 ± 0.0
Ile
4.096IleAla: 4.096 ± 1.395
0.0IleCys: 0.0 ± 0.0
2.73IleAsp: 2.73 ± 1.652
3.413IleGlu: 3.413 ± 1.632
1.365IlePhe: 1.365 ± 0.631
4.778IleGly: 4.778 ± 1.051
0.683IleHis: 0.683 ± 0.597
1.365IleIle: 1.365 ± 1.194
4.096IleLys: 4.096 ± 1.842
4.096IleLeu: 4.096 ± 1.695
0.683IleMet: 0.683 ± 0.409
2.73IleAsn: 2.73 ± 1.494
2.73IlePro: 2.73 ± 1.229
1.365IleGln: 1.365 ± 0.614
2.048IleArg: 2.048 ± 1.353
2.73IleSer: 2.73 ± 1.652
4.096IleThr: 4.096 ± 1.998
4.096IleVal: 4.096 ± 1.733
0.683IleTrp: 0.683 ± 0.451
4.778IleTyr: 4.778 ± 2.385
0.0IleXaa: 0.0 ± 0.0
Lys
6.826LysAla: 6.826 ± 5.157
2.73LysCys: 2.73 ± 1.494
4.096LysAsp: 4.096 ± 0.355
4.096LysGlu: 4.096 ± 2.394
2.73LysPhe: 2.73 ± 1.652
6.826LysGly: 6.826 ± 2.241
1.365LysHis: 1.365 ± 1.439
0.683LysIle: 0.683 ± 0.597
11.604LysLys: 11.604 ± 8.36
4.096LysLeu: 4.096 ± 1.842
1.365LysMet: 1.365 ± 0.563
2.73LysAsn: 2.73 ± 0.305
7.509LysPro: 7.509 ± 5.865
2.048LysGln: 2.048 ± 0.178
6.143LysArg: 6.143 ± 0.506
5.461LysSer: 5.461 ± 2.744
3.413LysThr: 3.413 ± 1.591
6.826LysVal: 6.826 ± 4.161
1.365LysTrp: 1.365 ± 0.578
0.683LysTyr: 0.683 ± 0.597
0.0LysXaa: 0.0 ± 0.0
Leu
4.096LeuAla: 4.096 ± 0.355
2.048LeuCys: 2.048 ± 0.974
5.461LeuAsp: 5.461 ± 1.219
0.683LeuGlu: 0.683 ± 0.597
4.096LeuPhe: 4.096 ± 0.675
4.096LeuGly: 4.096 ± 1.084
0.0LeuHis: 0.0 ± 0.0
7.509LeuIle: 7.509 ± 1.283
4.096LeuLys: 4.096 ± 1.842
4.778LeuLeu: 4.778 ± 2.195
2.048LeuMet: 2.048 ± 0.974
4.778LeuAsn: 4.778 ± 2.195
5.461LeuPro: 5.461 ± 1.47
4.096LeuGln: 4.096 ± 1.199
7.509LeuArg: 7.509 ± 1.13
8.191LeuSer: 8.191 ± 3.312
4.778LeuThr: 4.778 ± 1.051
4.778LeuVal: 4.778 ± 2.43
1.365LeuTrp: 1.365 ± 0.614
1.365LeuTyr: 1.365 ± 0.578
0.0LeuXaa: 0.0 ± 0.0
Met
0.683MetAla: 0.683 ± 0.451
0.683MetCys: 0.683 ± 0.597
0.683MetAsp: 0.683 ± 0.719
2.73MetGlu: 2.73 ± 2.387
0.0MetPhe: 0.0 ± 0.0
1.365MetGly: 1.365 ± 0.902
0.683MetHis: 0.683 ± 0.719
0.0MetIle: 0.0 ± 0.0
2.048MetLys: 2.048 ± 1.197
0.683MetLeu: 0.683 ± 0.451
1.365MetMet: 1.365 ± 0.614
1.365MetAsn: 1.365 ± 0.578
2.73MetPro: 2.73 ± 1.494
2.048MetGln: 2.048 ± 1.197
0.683MetArg: 0.683 ± 0.719
3.413MetSer: 3.413 ± 0.783
0.0MetThr: 0.0 ± 0.0
2.048MetVal: 2.048 ± 0.848
0.0MetTrp: 0.0 ± 0.0
1.365MetTyr: 1.365 ± 0.578
0.0MetXaa: 0.0 ± 0.0
Asn
3.413AsnAla: 3.413 ± 0.462
0.683AsnCys: 0.683 ± 0.597
1.365AsnAsp: 1.365 ± 0.578
3.413AsnGlu: 3.413 ± 0.749
0.683AsnPhe: 0.683 ± 0.719
8.874AsnGly: 8.874 ± 4.355
0.683AsnHis: 0.683 ± 0.597
2.73AsnIle: 2.73 ± 1.261
1.365AsnLys: 1.365 ± 0.614
4.096AsnLeu: 4.096 ± 1.022
1.365AsnMet: 1.365 ± 0.578
2.73AsnAsn: 2.73 ± 1.805
3.413AsnPro: 3.413 ± 1.646
2.048AsnGln: 2.048 ± 1.275
2.048AsnArg: 2.048 ± 1.79
4.096AsnSer: 4.096 ± 1.998
2.048AsnThr: 2.048 ± 1.197
3.413AsnVal: 3.413 ± 0.709
2.048AsnTrp: 2.048 ± 1.084
0.683AsnTyr: 0.683 ± 0.597
0.0AsnXaa: 0.0 ± 0.0
Pro
4.096ProAla: 4.096 ± 1.656
0.683ProCys: 0.683 ± 0.451
3.413ProAsp: 3.413 ± 1.646
2.73ProGlu: 2.73 ± 1.229
0.683ProPhe: 0.683 ± 0.719
0.683ProGly: 0.683 ± 0.451
2.048ProHis: 2.048 ± 0.178
4.096ProIle: 4.096 ± 1.791
6.826ProLys: 6.826 ± 7.193
5.461ProLeu: 5.461 ± 1.414
1.365ProMet: 1.365 ± 1.194
3.413ProAsn: 3.413 ± 0.783
2.73ProPro: 2.73 ± 0.305
2.048ProGln: 2.048 ± 0.178
3.413ProArg: 3.413 ± 0.462
4.096ProSer: 4.096 ± 1.998
4.778ProThr: 4.778 ± 1.33
3.413ProVal: 3.413 ± 0.783
0.683ProTrp: 0.683 ± 0.451
3.413ProTyr: 3.413 ± 0.462
0.0ProXaa: 0.0 ± 0.0
Gln
4.096GlnAla: 4.096 ± 1.892
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.096GlnGlu: 4.096 ± 3.394
4.778GlnPhe: 4.778 ± 3.158
0.683GlnGly: 0.683 ± 0.597
1.365GlnHis: 1.365 ± 1.194
3.413GlnIle: 3.413 ± 1.198
0.683GlnLys: 0.683 ± 0.597
4.778GlnLeu: 4.778 ± 1.096
1.365GlnMet: 1.365 ± 1.194
0.0GlnAsn: 0.0 ± 0.0
2.048GlnPro: 2.048 ± 1.275
2.048GlnGln: 2.048 ± 0.178
1.365GlnArg: 1.365 ± 1.439
2.73GlnSer: 2.73 ± 0.305
0.683GlnThr: 0.683 ± 0.451
3.413GlnVal: 3.413 ± 1.879
0.0GlnTrp: 0.0 ± 0.0
1.365GlnTyr: 1.365 ± 0.578
0.0GlnXaa: 0.0 ± 0.0
Arg
4.778ArgAla: 4.778 ± 2.451
1.365ArgCys: 1.365 ± 1.439
4.778ArgAsp: 4.778 ± 1.33
4.778ArgGlu: 4.778 ± 2.062
2.048ArgPhe: 2.048 ± 1.084
0.683ArgGly: 0.683 ± 0.597
0.683ArgHis: 0.683 ± 0.597
1.365ArgIle: 1.365 ± 0.902
5.461ArgLys: 5.461 ± 1.939
5.461ArgLeu: 5.461 ± 0.394
2.048ArgMet: 2.048 ± 0.974
2.048ArgAsn: 2.048 ± 0.178
4.096ArgPro: 4.096 ± 0.355
1.365ArgGln: 1.365 ± 0.631
2.048ArgArg: 2.048 ± 1.084
4.778ArgSer: 4.778 ± 2.047
2.048ArgThr: 2.048 ± 0.828
4.778ArgVal: 4.778 ± 1.565
2.048ArgTrp: 2.048 ± 0.848
3.413ArgTyr: 3.413 ± 1.379
0.0ArgXaa: 0.0 ± 0.0
Ser
6.826SerAla: 6.826 ± 2.345
0.683SerCys: 0.683 ± 0.451
2.048SerAsp: 2.048 ± 1.79
4.096SerGlu: 4.096 ± 0.355
2.73SerPhe: 2.73 ± 1.155
3.413SerGly: 3.413 ± 1.646
0.683SerHis: 0.683 ± 0.719
3.413SerIle: 3.413 ± 1.646
11.604SerLys: 11.604 ± 4.466
4.096SerLeu: 4.096 ± 1.199
0.0SerMet: 0.0 ± 0.0
2.048SerAsn: 2.048 ± 1.353
3.413SerPro: 3.413 ± 0.783
2.048SerGln: 2.048 ± 1.084
9.556SerArg: 9.556 ± 2.176
2.048SerSer: 2.048 ± 0.848
3.413SerThr: 3.413 ± 1.401
4.096SerVal: 4.096 ± 2.169
1.365SerTrp: 1.365 ± 0.631
2.048SerTyr: 2.048 ± 0.848
0.0SerXaa: 0.0 ± 0.0
Thr
4.096ThrAla: 4.096 ± 1.733
0.683ThrCys: 0.683 ± 0.597
2.73ThrAsp: 2.73 ± 1.261
2.048ThrGlu: 2.048 ± 1.275
1.365ThrPhe: 1.365 ± 0.631
2.73ThrGly: 2.73 ± 1.229
1.365ThrHis: 1.365 ± 0.578
4.096ThrIle: 4.096 ± 0.355
1.365ThrLys: 1.365 ± 0.631
1.365ThrLeu: 1.365 ± 0.902
2.048ThrMet: 2.048 ± 1.353
2.048ThrAsn: 2.048 ± 0.828
6.143ThrPro: 6.143 ± 1.957
1.365ThrGln: 1.365 ± 0.902
2.048ThrArg: 2.048 ± 0.828
2.73ThrSer: 2.73 ± 0.305
2.048ThrThr: 2.048 ± 0.974
4.096ThrVal: 4.096 ± 1.656
0.0ThrTrp: 0.0 ± 0.0
2.048ThrTyr: 2.048 ± 1.275
0.0ThrXaa: 0.0 ± 0.0
Val
7.509ValAla: 7.509 ± 2.265
0.0ValCys: 0.0 ± 0.0
6.143ValAsp: 6.143 ± 1.21
4.096ValGlu: 4.096 ± 1.395
1.365ValPhe: 1.365 ± 0.614
4.778ValGly: 4.778 ± 1.096
1.365ValHis: 1.365 ± 0.578
2.73ValIle: 2.73 ± 1.805
5.461ValLys: 5.461 ± 3.945
4.096ValLeu: 4.096 ± 1.022
0.0ValMet: 0.0 ± 0.0
4.778ValAsn: 4.778 ± 1.03
2.73ValPro: 2.73 ± 0.305
6.143ValGln: 6.143 ± 2.668
4.778ValArg: 4.778 ± 0.214
6.143ValSer: 6.143 ± 1.522
2.73ValThr: 2.73 ± 1.261
4.096ValVal: 4.096 ± 2.309
0.0ValTrp: 0.0 ± 0.0
2.048ValTyr: 2.048 ± 0.848
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.683TrpCys: 0.683 ± 0.719
0.683TrpAsp: 0.683 ± 0.451
0.0TrpGlu: 0.0 ± 0.0
0.683TrpPhe: 0.683 ± 0.451
0.683TrpGly: 0.683 ± 0.451
2.73TrpHis: 2.73 ± 1.229
0.683TrpIle: 0.683 ± 0.451
0.0TrpLys: 0.0 ± 0.0
2.73TrpLeu: 2.73 ± 0.614
0.683TrpMet: 0.683 ± 0.451
1.365TrpAsn: 1.365 ± 0.578
0.0TrpPro: 0.0 ± 0.0
0.683TrpGln: 0.683 ± 0.451
1.365TrpArg: 1.365 ± 0.578
0.683TrpSer: 0.683 ± 0.719
0.0TrpThr: 0.0 ± 0.0
0.683TrpVal: 0.683 ± 0.719
0.0TrpTrp: 0.0 ± 0.0
0.683TrpTyr: 0.683 ± 0.597
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.73TyrAla: 2.73 ± 1.652
0.683TyrCys: 0.683 ± 0.597
1.365TyrAsp: 1.365 ± 0.902
0.683TyrGlu: 0.683 ± 0.597
0.683TyrPhe: 0.683 ± 0.597
3.413TyrGly: 3.413 ± 1.575
0.683TyrHis: 0.683 ± 0.597
1.365TyrIle: 1.365 ± 0.578
4.096TyrLys: 4.096 ± 2.634
5.461TyrLeu: 5.461 ± 2.201
0.683TyrMet: 0.683 ± 0.719
1.365TyrAsn: 1.365 ± 0.578
2.73TyrPro: 2.73 ± 1.261
1.365TyrGln: 1.365 ± 0.578
2.73TyrArg: 2.73 ± 1.494
3.413TyrSer: 3.413 ± 0.749
1.365TyrThr: 1.365 ± 0.614
2.73TyrVal: 2.73 ± 1.229
0.0TyrTrp: 0.0 ± 0.0
2.73TyrTyr: 2.73 ± 1.229
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1466 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski