Amino acid dipepetide frequency for Parambassis ranga (Indian glassy fish)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.615AlaAla: 6.615 ± 0.031	1.21AlaCys: 1.21 ± 0.011	3.269AlaAsp: 3.269 ± 0.013	5.012AlaGlu: 5.012 ± 0.03	2.128AlaPhe: 2.128 ± 0.011	4.323AlaGly: 4.323 ± 0.019	1.454AlaHis: 1.454 ± 0.008	2.552AlaIle: 2.552 ± 0.011	3.425AlaLys: 3.425 ± 0.021	6.274AlaLeu: 6.274 ± 0.025	1.56AlaMet: 1.56 ± 0.01	2.181AlaAsn: 2.181 ± 0.012	3.769AlaPro: 3.769 ± 0.025	3.11AlaGln: 3.11 ± 0.02	3.093AlaArg: 3.093 ± 0.014	5.748AlaSer: 5.748 ± 0.019	3.669AlaThr: 3.669 ± 0.025	4.813AlaVal: 4.813 ± 0.018	0.588AlaTrp: 0.588 ± 0.006	1.409AlaTyr: 1.409 ± 0.009	0.001AlaXaa: 0.001 ± 0.0
Cys	1.093CysAla: 1.093 ± 0.008	0.576CysCys: 0.576 ± 0.006	1.145CysAsp: 1.145 ± 0.016	1.282CysGlu: 1.282 ± 0.014	0.778CysPhe: 0.778 ± 0.007	1.447CysGly: 1.447 ± 0.013	0.615CysHis: 0.615 ± 0.006	0.92CysIle: 0.92 ± 0.009	1.079CysLys: 1.079 ± 0.01	1.952CysLeu: 1.952 ± 0.012	0.424CysMet: 0.424 ± 0.005	0.766CysAsn: 0.766 ± 0.008	1.216CysPro: 1.216 ± 0.012	1.044CysGln: 1.044 ± 0.012	1.228CysArg: 1.228 ± 0.012	2.094CysSer: 2.094 ± 0.016	1.119CysThr: 1.119 ± 0.01	1.398CysVal: 1.398 ± 0.011	0.264CysTrp: 0.264 ± 0.004	0.562CysTyr: 0.562 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	2.98AspAla: 2.98 ± 0.014	1.102AspCys: 1.102 ± 0.01	3.239AspAsp: 3.239 ± 0.02	3.894AspGlu: 3.894 ± 0.019	1.978AspPhe: 1.978 ± 0.011	3.66AspGly: 3.66 ± 0.02	1.197AspHis: 1.197 ± 0.008	2.715AspIle: 2.715 ± 0.016	2.797AspLys: 2.797 ± 0.014	4.942AspLeu: 4.942 ± 0.019	1.354AspMet: 1.354 ± 0.008	1.983AspAsn: 1.983 ± 0.016	2.916AspPro: 2.916 ± 0.014	2.086AspGln: 2.086 ± 0.011	2.819AspArg: 2.819 ± 0.014	4.928AspSer: 4.928 ± 0.018	2.901AspThr: 2.901 ± 0.015	3.343AspVal: 3.343 ± 0.016	0.627AspTrp: 0.627 ± 0.005	1.499AspTyr: 1.499 ± 0.009	0.001AspXaa: 0.001 ± 0.0
Glu	4.983GluAla: 4.983 ± 0.03	1.174GluCys: 1.174 ± 0.011	4.726GluAsp: 4.726 ± 0.018	8.661GluGlu: 8.661 ± 0.053	1.865GluPhe: 1.865 ± 0.011	4.27GluGly: 4.27 ± 0.023	1.497GluHis: 1.497 ± 0.01	2.807GluIle: 2.807 ± 0.014	4.946GluLys: 4.946 ± 0.033	6.278GluLeu: 6.278 ± 0.029	1.768GluMet: 1.768 ± 0.01	2.75GluAsn: 2.75 ± 0.014	2.999GluPro: 2.999 ± 0.018	3.355GluGln: 3.355 ± 0.02	4.477GluArg: 4.477 ± 0.024	4.683GluSer: 4.683 ± 0.023	3.603GluThr: 3.603 ± 0.018	4.503GluVal: 4.503 ± 0.023	0.64GluTrp: 0.64 ± 0.006	1.59GluTyr: 1.59 ± 0.013	0.001GluXaa: 0.001 ± 0.0
Phe	1.687PheAla: 1.687 ± 0.01	0.828PheCys: 0.828 ± 0.007	1.659PheAsp: 1.659 ± 0.01	1.785PheGlu: 1.785 ± 0.01	1.338PhePhe: 1.338 ± 0.01	1.966PheGly: 1.966 ± 0.012	0.921PheHis: 0.921 ± 0.007	1.676PheIle: 1.676 ± 0.011	1.72PheLys: 1.72 ± 0.012	3.374PheLeu: 3.374 ± 0.018	0.744PheMet: 0.744 ± 0.006	1.363PheAsn: 1.363 ± 0.009	1.667PhePro: 1.667 ± 0.012	1.542PheGln: 1.542 ± 0.009	1.739PheArg: 1.739 ± 0.012	3.163PheSer: 3.163 ± 0.014	2.174PheThr: 2.174 ± 0.013	1.962PheVal: 1.962 ± 0.011	0.4PheTrp: 0.4 ± 0.004	1.061PheTyr: 1.061 ± 0.008	0.001PheXaa: 0.001 ± 0.0
Gly	3.911GlyAla: 3.911 ± 0.019	1.178GlyCys: 1.178 ± 0.011	3.237GlyAsp: 3.237 ± 0.018	4.102GlyGlu: 4.102 ± 0.02	2.236GlyPhe: 2.236 ± 0.015	5.47GlyGly: 5.47 ± 0.04	1.637GlyHis: 1.637 ± 0.01	2.421GlyIle: 2.421 ± 0.013	3.418GlyLys: 3.418 ± 0.02	5.299GlyLeu: 5.299 ± 0.022	1.433GlyMet: 1.433 ± 0.01	2.378GlyAsn: 2.378 ± 0.015	3.477GlyPro: 3.477 ± 0.035	2.861GlyGln: 2.861 ± 0.017	3.577GlyArg: 3.577 ± 0.018	5.921GlySer: 5.921 ± 0.023	3.368GlyThr: 3.368 ± 0.013	3.824GlyVal: 3.824 ± 0.021	0.694GlyTrp: 0.694 ± 0.007	1.757GlyTyr: 1.757 ± 0.013	0.001GlyXaa: 0.001 ± 0.0
His	1.307HisAla: 1.307 ± 0.008	0.733HisCys: 0.733 ± 0.006	1.0HisAsp: 1.0 ± 0.006	1.24HisGlu: 1.24 ± 0.007	0.967HisPhe: 0.967 ± 0.006	1.501HisGly: 1.501 ± 0.01	1.157HisHis: 1.157 ± 0.013	1.307HisIle: 1.307 ± 0.008	1.302HisLys: 1.302 ± 0.009	2.623HisLeu: 2.623 ± 0.014	0.674HisMet: 0.674 ± 0.006	1.042HisAsn: 1.042 ± 0.008	1.656HisPro: 1.656 ± 0.012	1.361HisGln: 1.361 ± 0.011	1.656HisArg: 1.656 ± 0.008	2.624HisSer: 2.624 ± 0.013	1.678HisThr: 1.678 ± 0.01	1.453HisVal: 1.453 ± 0.008	0.292HisTrp: 0.292 ± 0.003	0.824HisTyr: 0.824 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.369IleAla: 2.369 ± 0.011	0.962IleCys: 0.962 ± 0.007	2.037IleAsp: 2.037 ± 0.012	2.356IleGlu: 2.356 ± 0.014	1.572IlePhe: 1.572 ± 0.01	2.089IleGly: 2.089 ± 0.011	1.236IleHis: 1.236 ± 0.008	2.256IleIle: 2.256 ± 0.013	2.478IleLys: 2.478 ± 0.016	3.974IleLeu: 3.974 ± 0.016	0.986IleMet: 0.986 ± 0.008	2.0IleAsn: 2.0 ± 0.019	2.486IlePro: 2.486 ± 0.012	2.24IleGln: 2.24 ± 0.012	2.38IleArg: 2.38 ± 0.01	3.703IleSer: 3.703 ± 0.015	2.889IleThr: 2.889 ± 0.024	2.369IleVal: 2.369 ± 0.013	0.429IleTrp: 0.429 ± 0.005	1.241IleTyr: 1.241 ± 0.008	0.001IleXaa: 0.001 ± 0.0
Lys	3.829LysAla: 3.829 ± 0.022	0.952LysCys: 0.952 ± 0.009	3.408LysAsp: 3.408 ± 0.02	4.995LysGlu: 4.995 ± 0.028	1.478LysPhe: 1.478 ± 0.011	3.229LysGly: 3.229 ± 0.024	1.408LysHis: 1.408 ± 0.009	2.349LysIle: 2.349 ± 0.012	4.623LysLys: 4.623 ± 0.03	4.91LysLeu: 4.91 ± 0.021	1.462LysMet: 1.462 ± 0.011	2.245LysAsn: 2.245 ± 0.012	3.048LysPro: 3.048 ± 0.021	2.712LysGln: 2.712 ± 0.017	3.395LysArg: 3.395 ± 0.015	3.949LysSer: 3.949 ± 0.019	3.27LysThr: 3.27 ± 0.016	3.509LysVal: 3.509 ± 0.018	0.541LysTrp: 0.541 ± 0.006	1.417LysTyr: 1.417 ± 0.013	0.001LysXaa: 0.001 ± 0.0
Leu	5.762LeuAla: 5.762 ± 0.02	2.04LeuCys: 2.04 ± 0.012	4.831LeuAsp: 4.831 ± 0.018	6.503LeuGlu: 6.503 ± 0.033	2.979LeuPhe: 2.979 ± 0.018	4.759LeuGly: 4.759 ± 0.021	2.695LeuHis: 2.695 ± 0.013	3.546LeuIle: 3.546 ± 0.014	5.538LeuLys: 5.538 ± 0.026	9.611LeuLeu: 9.611 ± 0.041	2.049LeuMet: 2.049 ± 0.01	3.539LeuAsn: 3.539 ± 0.015	5.379LeuPro: 5.379 ± 0.023	5.693LeuGln: 5.693 ± 0.03	5.518LeuArg: 5.518 ± 0.021	8.447LeuSer: 8.447 ± 0.029	5.246LeuThr: 5.246 ± 0.019	5.052LeuVal: 5.052 ± 0.018	0.938LeuTrp: 0.938 ± 0.007	2.356LeuTyr: 2.356 ± 0.012	0.001LeuXaa: 0.001 ± 0.0
Met	1.884MetAla: 1.884 ± 0.009	0.452MetCys: 0.452 ± 0.005	1.438MetAsp: 1.438 ± 0.008	2.052MetGlu: 2.052 ± 0.01	0.76MetPhe: 0.76 ± 0.007	1.38MetGly: 1.38 ± 0.01	0.469MetHis: 0.469 ± 0.004	0.817MetIle: 0.817 ± 0.006	1.497MetLys: 1.497 ± 0.008	1.994MetLeu: 1.994 ± 0.011	0.703MetMet: 0.703 ± 0.006	0.887MetAsn: 0.887 ± 0.007	1.121MetPro: 1.121 ± 0.011	1.034MetGln: 1.034 ± 0.008	1.183MetArg: 1.183 ± 0.006	1.932MetSer: 1.932 ± 0.01	1.29MetThr: 1.29 ± 0.008	1.489MetVal: 1.489 ± 0.009	0.237MetTrp: 0.237 ± 0.003	0.605MetTyr: 0.605 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.14AsnAla: 2.14 ± 0.014	0.797AsnCys: 0.797 ± 0.009	1.673AsnAsp: 1.673 ± 0.011	2.075AsnGlu: 2.075 ± 0.01	1.283AsnPhe: 1.283 ± 0.009	2.714AsnGly: 2.714 ± 0.018	1.026AsnHis: 1.026 ± 0.008	2.145AsnIle: 2.145 ± 0.016	2.236AsnLys: 2.236 ± 0.013	3.517AsnLeu: 3.517 ± 0.016	1.051AsnMet: 1.051 ± 0.007	1.86AsnAsn: 1.86 ± 0.018	2.19AsnPro: 2.19 ± 0.011	1.833AsnGln: 1.833 ± 0.01	1.954AsnArg: 1.954 ± 0.011	3.314AsnSer: 3.314 ± 0.015	2.452AsnThr: 2.452 ± 0.019	2.19AsnVal: 2.19 ± 0.01	0.391AsnTrp: 0.391 ± 0.005	1.053AsnTyr: 1.053 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	4.602ProAla: 4.602 ± 0.025	1.013ProCys: 1.013 ± 0.01	3.046ProAsp: 3.046 ± 0.02	3.934ProGlu: 3.934 ± 0.023	1.677ProPhe: 1.677 ± 0.01	4.296ProGly: 4.296 ± 0.044	1.598ProHis: 1.598 ± 0.012	1.907ProIle: 1.907 ± 0.011	2.667ProLys: 2.667 ± 0.023	4.863ProLeu: 4.863 ± 0.019	1.066ProMet: 1.066 ± 0.008	1.9ProAsn: 1.9 ± 0.011	6.289ProPro: 6.289 ± 0.046	2.917ProGln: 2.917 ± 0.019	2.705ProArg: 2.705 ± 0.015	6.087ProSer: 6.087 ± 0.028	3.517ProThr: 3.517 ± 0.021	4.02ProVal: 4.02 ± 0.02	0.5ProTrp: 0.5 ± 0.006	1.376ProTyr: 1.376 ± 0.01	0.001ProXaa: 0.001 ± 0.0
Gln	3.43GlnAla: 3.43 ± 0.021	0.981GlnCys: 0.981 ± 0.015	2.447GlnAsp: 2.447 ± 0.012	3.787GlnGlu: 3.787 ± 0.02	1.305GlnPhe: 1.305 ± 0.009	2.829GlnGly: 2.829 ± 0.014	1.477GlnHis: 1.477 ± 0.012	1.938GlnIle: 1.938 ± 0.011	2.702GlnLys: 2.702 ± 0.015	4.683GlnLeu: 4.683 ± 0.025	1.168GlnMet: 1.168 ± 0.008	1.808GlnAsn: 1.808 ± 0.01	2.888GlnPro: 2.888 ± 0.021	3.917GlnGln: 3.917 ± 0.039	3.251GlnArg: 3.251 ± 0.017	3.893GlnSer: 3.893 ± 0.019	2.824GlnThr: 2.824 ± 0.013	2.848GlnVal: 2.848 ± 0.014	0.556GlnTrp: 0.556 ± 0.005	1.265GlnTyr: 1.265 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	3.425ArgAla: 3.425 ± 0.014	1.21ArgCys: 1.21 ± 0.012	2.927ArgAsp: 2.927 ± 0.014	4.04ArgGlu: 4.04 ± 0.019	1.791ArgPhe: 1.791 ± 0.01	3.431ArgGly: 3.431 ± 0.021	1.591ArgHis: 1.591 ± 0.009	2.245ArgIle: 2.245 ± 0.011	3.558ArgLys: 3.558 ± 0.017	5.233ArgLeu: 5.233 ± 0.022	1.268ArgMet: 1.268 ± 0.008	2.035ArgAsn: 2.035 ± 0.01	3.006ArgPro: 3.006 ± 0.015	2.846ArgGln: 2.846 ± 0.015	4.417ArgArg: 4.417 ± 0.022	4.762ArgSer: 4.762 ± 0.02	2.948ArgThr: 2.948 ± 0.011	3.223ArgVal: 3.223 ± 0.017	0.657ArgTrp: 0.657 ± 0.007	1.456ArgTyr: 1.456 ± 0.008	0.001ArgXaa: 0.001 ± 0.0
Ser	5.953SerAla: 5.953 ± 0.02	2.005SerCys: 2.005 ± 0.019	4.694SerAsp: 4.694 ± 0.02	5.283SerGlu: 5.283 ± 0.022	2.888SerPhe: 2.888 ± 0.013	5.696SerGly: 5.696 ± 0.021	2.33SerHis: 2.33 ± 0.013	3.318SerIle: 3.318 ± 0.014	4.15SerLys: 4.15 ± 0.017	8.382SerLeu: 8.382 ± 0.03	1.888SerMet: 1.888 ± 0.008	3.06SerAsn: 3.06 ± 0.015	6.717SerPro: 6.717 ± 0.036	4.233SerGln: 4.233 ± 0.018	4.662SerArg: 4.662 ± 0.021	11.639SerSer: 11.639 ± 0.052	5.323SerThr: 5.323 ± 0.024	5.575SerVal: 5.575 ± 0.02	0.96SerTrp: 0.96 ± 0.008	2.124SerTyr: 2.124 ± 0.011	0.001SerXaa: 0.001 ± 0.0
Thr	4.373ThrAla: 4.373 ± 0.027	1.31ThrCys: 1.31 ± 0.015	3.099ThrAsp: 3.099 ± 0.012	4.089ThrGlu: 4.089 ± 0.019	1.948ThrPhe: 1.948 ± 0.011	3.717ThrGly: 3.717 ± 0.016	1.474ThrHis: 1.474 ± 0.009	2.412ThrIle: 2.412 ± 0.016	2.802ThrLys: 2.802 ± 0.015	5.33ThrLeu: 5.33 ± 0.016	1.236ThrMet: 1.236 ± 0.008	2.057ThrAsn: 2.057 ± 0.017	4.126ThrPro: 4.126 ± 0.024	2.612ThrGln: 2.612 ± 0.015	2.464ThrArg: 2.464 ± 0.011	5.301ThrSer: 5.301 ± 0.021	4.3ThrThr: 4.3 ± 0.083	4.308ThrVal: 4.308 ± 0.025	0.622ThrTrp: 0.622 ± 0.007	1.382ThrTyr: 1.382 ± 0.009	0.0ThrXaa: 0.0 ± 0.0
Val	3.96ValAla: 3.96 ± 0.018	1.597ValCys: 1.597 ± 0.012	3.202ValAsp: 3.202 ± 0.016	4.254ValGlu: 4.254 ± 0.023	2.371ValPhe: 2.371 ± 0.013	3.304ValGly: 3.304 ± 0.015	1.573ValHis: 1.573 ± 0.009	2.861ValIle: 2.861 ± 0.017	3.693ValLys: 3.693 ± 0.024	5.802ValLeu: 5.802 ± 0.018	1.449ValMet: 1.449 ± 0.008	2.455ValAsn: 2.455 ± 0.014	3.376ValPro: 3.376 ± 0.016	2.894ValGln: 2.894 ± 0.012	3.158ValArg: 3.158 ± 0.014	5.474ValSer: 5.474 ± 0.021	4.11ValThr: 4.11 ± 0.025	4.206ValVal: 4.206 ± 0.02	0.699ValTrp: 0.699 ± 0.007	1.72ValTyr: 1.72 ± 0.01	0.001ValXaa: 0.001 ± 0.0
Trp	0.594TrpAla: 0.594 ± 0.005	0.219TrpCys: 0.219 ± 0.003	0.591TrpAsp: 0.591 ± 0.006	0.704TrpGlu: 0.704 ± 0.006	0.415TrpPhe: 0.415 ± 0.004	0.558TrpGly: 0.558 ± 0.007	0.254TrpHis: 0.254 ± 0.003	0.498TrpIle: 0.498 ± 0.005	0.656TrpLys: 0.656 ± 0.006	1.053TrpLeu: 1.053 ± 0.008	0.317TrpMet: 0.317 ± 0.003	0.451TrpAsn: 0.451 ± 0.005	0.392TrpPro: 0.392 ± 0.004	0.461TrpGln: 0.461 ± 0.005	0.705TrpArg: 0.705 ± 0.006	0.909TrpSer: 0.909 ± 0.008	0.657TrpThr: 0.657 ± 0.007	0.618TrpVal: 0.618 ± 0.005	0.177TrpTrp: 0.177 ± 0.005	0.313TrpTyr: 0.313 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.304TyrAla: 1.304 ± 0.009	0.664TyrCys: 0.664 ± 0.008	1.293TyrAsp: 1.293 ± 0.01	1.529TyrGlu: 1.529 ± 0.009	1.011TyrPhe: 1.011 ± 0.008	1.56TyrGly: 1.56 ± 0.012	0.789TyrHis: 0.789 ± 0.008	1.363TyrIle: 1.363 ± 0.01	1.441TyrLys: 1.441 ± 0.018	2.388TyrLeu: 2.388 ± 0.013	0.623TyrMet: 0.623 ± 0.005	1.133TyrAsn: 1.133 ± 0.009	1.26TyrPro: 1.26 ± 0.009	1.247TyrGln: 1.247 ± 0.008	1.686TyrArg: 1.686 ± 0.013	2.307TyrSer: 2.307 ± 0.012	1.624TyrThr: 1.624 ± 0.012	1.456TyrVal: 1.456 ± 0.01	0.331TyrTrp: 0.331 ± 0.005	0.89TyrTyr: 0.89 ± 0.007	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 35559 proteins (26690903 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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