Amino acid dipepetide frequency for Pepper yellow leaf curl virus PSSWS-14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.95AlaAla: 9.95 ± 3.256
0.995AlaCys: 0.995 ± 0.808
0.0AlaAsp: 0.0 ± 0.0
5.97AlaGlu: 5.97 ± 2.101
1.99AlaPhe: 1.99 ± 1.475
1.99AlaGly: 1.99 ± 1.122
0.0AlaHis: 0.0 ± 0.0
2.985AlaIle: 2.985 ± 0.998
3.98AlaLys: 3.98 ± 1.16
5.97AlaLeu: 5.97 ± 2.268
0.995AlaMet: 0.995 ± 0.735
2.985AlaAsn: 2.985 ± 1.473
3.98AlaPro: 3.98 ± 1.546
5.97AlaGln: 5.97 ± 2.344
2.985AlaArg: 2.985 ± 2.204
2.985AlaSer: 2.985 ± 2.425
4.975AlaThr: 4.975 ± 2.185
0.995AlaVal: 0.995 ± 1.173
2.985AlaTrp: 2.985 ± 1.273
0.995AlaTyr: 0.995 ± 1.022
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.99CysCys: 1.99 ± 2.044
0.0CysAsp: 0.0 ± 0.0
1.99CysGlu: 1.99 ± 0.773
0.995CysPhe: 0.995 ± 1.173
1.99CysGly: 1.99 ± 1.122
0.995CysHis: 0.995 ± 1.165
0.0CysIle: 0.0 ± 0.0
1.99CysLys: 1.99 ± 1.253
0.995CysLeu: 0.995 ± 1.022
0.995CysMet: 0.995 ± 1.022
0.995CysAsn: 0.995 ± 0.735
4.975CysPro: 4.975 ± 2.435
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.99CysSer: 1.99 ± 2.33
0.995CysThr: 0.995 ± 0.808
1.99CysVal: 1.99 ± 1.616
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.985AspAla: 2.985 ± 2.204
0.995AspCys: 0.995 ± 1.165
0.995AspAsp: 0.995 ± 0.735
1.99AspGlu: 1.99 ± 0.773
0.995AspPhe: 0.995 ± 1.173
2.985AspGly: 2.985 ± 2.204
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
1.99AspLys: 1.99 ± 1.47
5.97AspLeu: 5.97 ± 1.793
0.995AspMet: 0.995 ± 1.173
1.99AspAsn: 1.99 ± 1.616
1.99AspPro: 1.99 ± 1.033
1.99AspGln: 1.99 ± 1.033
2.985AspArg: 2.985 ± 1.4
1.99AspSer: 1.99 ± 2.33
2.985AspThr: 2.985 ± 0.998
5.97AspVal: 5.97 ± 1.783
0.995AspTrp: 0.995 ± 0.735
1.99AspTyr: 1.99 ± 1.113
0.0AspXaa: 0.0 ± 0.0
Glu
5.97GluAla: 5.97 ± 1.657
0.0GluCys: 0.0 ± 0.0
1.99GluAsp: 1.99 ± 1.47
4.975GluGlu: 4.975 ± 2.728
1.99GluPhe: 1.99 ± 1.033
2.985GluGly: 2.985 ± 0.98
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
2.985GluLys: 2.985 ± 2.204
2.985GluLeu: 2.985 ± 1.273
0.0GluMet: 0.0 ± 0.0
4.975GluAsn: 4.975 ± 2.113
0.995GluPro: 0.995 ± 0.808
3.98GluGln: 3.98 ± 2.524
0.0GluArg: 0.0 ± 0.0
3.98GluSer: 3.98 ± 1.987
3.98GluThr: 3.98 ± 2.896
1.99GluVal: 1.99 ± 1.113
0.995GluTrp: 0.995 ± 1.165
2.985GluTyr: 2.985 ± 1.478
0.0GluXaa: 0.0 ± 0.0
Phe
0.995PheAla: 0.995 ± 0.735
0.995PheCys: 0.995 ± 0.808
1.99PheAsp: 1.99 ± 1.47
0.995PheGlu: 0.995 ± 0.808
1.99PhePhe: 1.99 ± 1.287
0.995PheGly: 0.995 ± 0.808
3.98PheHis: 3.98 ± 1.497
0.995PheIle: 0.995 ± 0.735
4.975PheLys: 4.975 ± 3.238
4.975PheLeu: 4.975 ± 2.188
0.995PheMet: 0.995 ± 0.735
2.985PheAsn: 2.985 ± 1.571
0.995PhePro: 0.995 ± 1.022
4.975PheGln: 4.975 ± 2.728
3.98PheArg: 3.98 ± 1.144
2.985PheSer: 2.985 ± 0.98
0.995PheThr: 0.995 ± 1.165
2.985PheVal: 2.985 ± 1.473
0.995PheTrp: 0.995 ± 0.808
1.99PheTyr: 1.99 ± 1.616
0.0PheXaa: 0.0 ± 0.0
Gly
3.98GlyAla: 3.98 ± 2.244
1.99GlyCys: 1.99 ± 1.287
1.99GlyAsp: 1.99 ± 1.122
3.98GlyGlu: 3.98 ± 1.144
2.985GlyPhe: 2.985 ± 1.532
5.97GlyGly: 5.97 ± 2.022
1.99GlyHis: 1.99 ± 1.122
2.985GlyIle: 2.985 ± 0.928
6.965GlyLys: 6.965 ± 2.117
1.99GlyLeu: 1.99 ± 1.122
0.995GlyMet: 0.995 ± 0.808
0.0GlyAsn: 0.0 ± 0.0
2.985GlyPro: 2.985 ± 1.273
1.99GlyGln: 1.99 ± 0.773
1.99GlyArg: 1.99 ± 0.773
3.98GlySer: 3.98 ± 1.422
0.0GlyThr: 0.0 ± 0.0
3.98GlyVal: 3.98 ± 2.271
0.0GlyTrp: 0.0 ± 0.0
1.99GlyTyr: 1.99 ± 1.615
0.0GlyXaa: 0.0 ± 0.0
His
0.995HisAla: 0.995 ± 0.808
1.99HisCys: 1.99 ± 1.475
0.995HisAsp: 0.995 ± 0.808
0.0HisGlu: 0.0 ± 0.0
2.985HisPhe: 2.985 ± 1.478
2.985HisGly: 2.985 ± 2.454
0.995HisHis: 0.995 ± 1.165
1.99HisIle: 1.99 ± 2.346
0.995HisLys: 0.995 ± 1.173
2.985HisLeu: 2.985 ± 1.496
0.0HisMet: 0.0 ± 0.0
2.985HisAsn: 2.985 ± 1.478
2.985HisPro: 2.985 ± 1.473
1.99HisGln: 1.99 ± 1.287
5.97HisArg: 5.97 ± 3.579
2.985HisSer: 2.985 ± 1.354
2.985HisThr: 2.985 ± 2.425
1.99HisVal: 1.99 ± 1.033
0.0HisTrp: 0.0 ± 0.0
0.995HisTyr: 0.995 ± 0.735
0.0HisXaa: 0.0 ± 0.0
Ile
0.995IleAla: 0.995 ± 1.165
0.995IleCys: 0.995 ± 1.022
3.98IleAsp: 3.98 ± 1.16
2.985IleGlu: 2.985 ± 1.478
4.975IlePhe: 4.975 ± 2.704
1.99IleGly: 1.99 ± 1.262
0.995IleHis: 0.995 ± 1.173
3.98IleIle: 3.98 ± 1.048
4.975IleLys: 4.975 ± 1.452
1.99IleLeu: 1.99 ± 1.475
0.995IleMet: 0.995 ± 0.944
2.985IleAsn: 2.985 ± 1.354
1.99IlePro: 1.99 ± 1.47
3.98IleGln: 3.98 ± 2.051
4.975IleArg: 4.975 ± 0.898
0.0IleSer: 0.0 ± 0.0
2.985IleThr: 2.985 ± 1.765
1.99IleVal: 1.99 ± 0.773
2.985IleTrp: 2.985 ± 3.519
0.995IleTyr: 0.995 ± 0.808
0.0IleXaa: 0.0 ± 0.0
Lys
2.985LysAla: 2.985 ± 1.478
1.99LysCys: 1.99 ± 1.113
2.985LysAsp: 2.985 ± 1.919
4.975LysGlu: 4.975 ± 2.628
0.995LysPhe: 0.995 ± 1.173
1.99LysGly: 1.99 ± 1.47
1.99LysHis: 1.99 ± 1.47
2.985LysIle: 2.985 ± 2.318
1.99LysLys: 1.99 ± 2.33
3.98LysLeu: 3.98 ± 1.497
0.0LysMet: 0.0 ± 0.0
7.96LysAsn: 7.96 ± 1.747
1.99LysPro: 1.99 ± 0.773
0.995LysGln: 0.995 ± 0.735
3.98LysArg: 3.98 ± 3.233
8.955LysSer: 8.955 ± 1.931
0.995LysThr: 0.995 ± 0.735
5.97LysVal: 5.97 ± 2.483
0.0LysTrp: 0.0 ± 0.0
2.985LysTyr: 2.985 ± 0.998
0.0LysXaa: 0.0 ± 0.0
Leu
1.99LeuAla: 1.99 ± 1.475
2.985LeuCys: 2.985 ± 1.273
4.975LeuAsp: 4.975 ± 2.541
4.975LeuGlu: 4.975 ± 1.404
2.985LeuPhe: 2.985 ± 0.98
1.99LeuGly: 1.99 ± 1.113
7.96LeuHis: 7.96 ± 1.494
2.985LeuIle: 2.985 ± 1.348
5.97LeuLys: 5.97 ± 2.314
3.98LeuLeu: 3.98 ± 1.494
0.0LeuMet: 0.0 ± 0.0
2.985LeuAsn: 2.985 ± 1.273
3.98LeuPro: 3.98 ± 1.403
3.98LeuGln: 3.98 ± 2.896
7.96LeuArg: 7.96 ± 6.106
2.985LeuSer: 2.985 ± 1.354
1.99LeuThr: 1.99 ± 1.47
1.99LeuVal: 1.99 ± 1.253
0.995LeuTrp: 0.995 ± 1.173
4.975LeuTyr: 4.975 ± 1.997
0.0LeuXaa: 0.0 ± 0.0
Met
1.99MetAla: 1.99 ± 0.773
0.0MetCys: 0.0 ± 0.0
2.985MetAsp: 2.985 ± 2.298
0.0MetGlu: 0.0 ± 0.0
0.995MetPhe: 0.995 ± 0.808
0.995MetGly: 0.995 ± 0.735
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.995MetLeu: 0.995 ± 1.022
0.0MetMet: 0.0 ± 0.0
0.995MetAsn: 0.995 ± 0.808
1.99MetPro: 1.99 ± 0.773
0.0MetGln: 0.0 ± 0.0
0.995MetArg: 0.995 ± 1.165
1.99MetSer: 1.99 ± 1.616
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.99MetTrp: 1.99 ± 1.033
0.995MetTyr: 0.995 ± 0.808
0.0MetXaa: 0.0 ± 0.0
Asn
4.975AsnAla: 4.975 ± 2.628
1.99AsnCys: 1.99 ± 1.122
2.985AsnAsp: 2.985 ± 1.273
0.995AsnGlu: 0.995 ± 0.808
0.995AsnPhe: 0.995 ± 0.735
1.99AsnGly: 1.99 ± 1.113
3.98AsnHis: 3.98 ± 2.438
3.98AsnIle: 3.98 ± 1.099
0.0AsnLys: 0.0 ± 0.0
3.98AsnLeu: 3.98 ± 1.462
1.99AsnMet: 1.99 ± 1.515
7.96AsnAsn: 7.96 ± 2.199
4.975AsnPro: 4.975 ± 0.898
0.0AsnGln: 0.0 ± 0.0
2.985AsnArg: 2.985 ± 1.4
0.995AsnSer: 0.995 ± 0.735
3.98AsnThr: 3.98 ± 1.497
6.965AsnVal: 6.965 ± 1.816
0.995AsnTrp: 0.995 ± 0.735
4.975AsnTyr: 4.975 ± 1.452
0.0AsnXaa: 0.0 ± 0.0
Pro
0.995ProAla: 0.995 ± 0.808
1.99ProCys: 1.99 ± 1.253
0.995ProAsp: 0.995 ± 1.022
4.975ProGlu: 4.975 ± 1.973
1.99ProPhe: 1.99 ± 1.033
1.99ProGly: 1.99 ± 0.773
2.985ProHis: 2.985 ± 1.249
1.99ProIle: 1.99 ± 1.47
4.975ProLys: 4.975 ± 2.628
4.975ProLeu: 4.975 ± 1.404
1.99ProMet: 1.99 ± 1.616
4.975ProAsn: 4.975 ± 2.704
1.99ProPro: 1.99 ± 1.47
2.985ProGln: 2.985 ± 2.56
3.98ProArg: 3.98 ± 1.494
3.98ProSer: 3.98 ± 2.01
2.985ProThr: 2.985 ± 1.273
2.985ProVal: 2.985 ± 1.805
0.995ProTrp: 0.995 ± 0.735
0.995ProTyr: 0.995 ± 0.808
0.0ProXaa: 0.0 ± 0.0
Gln
3.98GlnAla: 3.98 ± 1.099
0.995GlnCys: 0.995 ± 0.735
0.0GlnAsp: 0.0 ± 0.0
1.99GlnGlu: 1.99 ± 0.773
4.975GlnPhe: 4.975 ± 2.704
2.985GlnGly: 2.985 ± 1.249
0.995GlnHis: 0.995 ± 1.165
5.97GlnIle: 5.97 ± 2.161
0.995GlnLys: 0.995 ± 1.165
0.995GlnLeu: 0.995 ± 1.173
0.0GlnMet: 0.0 ± 0.89
0.995GlnAsn: 0.995 ± 1.173
1.99GlnPro: 1.99 ± 2.33
2.985GlnGln: 2.985 ± 2.166
2.985GlnArg: 2.985 ± 0.98
3.98GlnSer: 3.98 ± 1.866
2.985GlnThr: 2.985 ± 1.348
4.975GlnVal: 4.975 ± 1.945
0.0GlnTrp: 0.0 ± 0.0
1.99GlnTyr: 1.99 ± 1.616
0.0GlnXaa: 0.0 ± 0.0
Arg
1.99ArgAla: 1.99 ± 1.262
1.99ArgCys: 1.99 ± 2.044
2.985ArgAsp: 2.985 ± 1.4
1.99ArgGlu: 1.99 ± 1.033
3.98ArgPhe: 3.98 ± 3.233
5.97ArgGly: 5.97 ± 1.884
4.975ArgHis: 4.975 ± 1.15
2.985ArgIle: 2.985 ± 0.98
1.99ArgLys: 1.99 ± 1.262
2.985ArgLeu: 2.985 ± 1.571
0.0ArgMet: 0.0 ± 0.0
1.99ArgAsn: 1.99 ± 1.47
5.97ArgPro: 5.97 ± 0.885
0.0ArgGln: 0.0 ± 0.0
7.96ArgArg: 7.96 ± 4.818
4.975ArgSer: 4.975 ± 1.676
2.985ArgThr: 2.985 ± 0.928
5.97ArgVal: 5.97 ± 1.884
0.0ArgTrp: 0.0 ± 0.0
1.99ArgTyr: 1.99 ± 1.572
0.0ArgXaa: 0.0 ± 0.0
Ser
3.98SerAla: 3.98 ± 1.065
0.0SerCys: 0.0 ± 0.0
5.97SerAsp: 5.97 ± 1.621
0.995SerGlu: 0.995 ± 1.022
3.98SerPhe: 3.98 ± 1.16
0.995SerGly: 0.995 ± 1.165
0.995SerHis: 0.995 ± 1.165
5.97SerIle: 5.97 ± 2.066
4.975SerLys: 4.975 ± 1.419
4.975SerLeu: 4.975 ± 1.464
0.0SerMet: 0.0 ± 0.0
2.985SerAsn: 2.985 ± 0.928
4.975SerPro: 4.975 ± 2.632
1.99SerGln: 1.99 ± 1.287
1.99SerArg: 1.99 ± 1.113
12.935SerSer: 12.935 ± 4.627
5.97SerThr: 5.97 ± 2.99
3.98SerVal: 3.98 ± 3.11
0.995SerTrp: 0.995 ± 0.735
4.975SerTyr: 4.975 ± 1.676
0.0SerXaa: 0.0 ± 0.0
Thr
4.975ThrAla: 4.975 ± 1.241
0.0ThrCys: 0.0 ± 0.0
0.995ThrAsp: 0.995 ± 1.173
1.99ThrGlu: 1.99 ± 0.773
0.995ThrPhe: 0.995 ± 0.735
4.975ThrGly: 4.975 ± 1.292
3.98ThrHis: 3.98 ± 2.152
2.985ThrIle: 2.985 ± 1.273
2.985ThrLys: 2.985 ± 1.919
1.99ThrLeu: 1.99 ± 1.253
0.995ThrMet: 0.995 ± 0.735
2.985ThrAsn: 2.985 ± 1.805
1.99ThrPro: 1.99 ± 1.253
2.985ThrGln: 2.985 ± 1.249
2.985ThrArg: 2.985 ± 1.765
3.98ThrSer: 3.98 ± 1.16
0.995ThrThr: 0.995 ± 0.808
3.98ThrVal: 3.98 ± 1.989
0.0ThrTrp: 0.0 ± 0.0
2.985ThrTyr: 2.985 ± 1.473
0.0ThrXaa: 0.0 ± 0.0
Val
1.99ValAla: 1.99 ± 1.033
0.995ValCys: 0.995 ± 0.735
1.99ValAsp: 1.99 ± 1.47
0.0ValGlu: 0.0 ± 0.0
3.98ValPhe: 3.98 ± 1.462
2.985ValGly: 2.985 ± 2.139
1.99ValHis: 1.99 ± 1.475
2.985ValIle: 2.985 ± 1.478
4.975ValLys: 4.975 ± 1.464
7.96ValLeu: 7.96 ± 4.272
0.995ValMet: 0.995 ± 0.808
2.985ValAsn: 2.985 ± 1.765
3.98ValPro: 3.98 ± 1.048
5.97ValGln: 5.97 ± 2.695
1.99ValArg: 1.99 ± 0.773
2.985ValSer: 2.985 ± 1.765
5.97ValThr: 5.97 ± 3.727
3.98ValVal: 3.98 ± 2.37
0.995ValTrp: 0.995 ± 0.808
6.965ValTyr: 6.965 ± 2.531
0.0ValXaa: 0.0 ± 0.0
Trp
2.985TrpAla: 2.985 ± 2.204
0.0TrpCys: 0.0 ± 0.0
1.99TrpAsp: 1.99 ± 1.572
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.995TrpGly: 0.995 ± 0.735
0.995TrpHis: 0.995 ± 1.173
0.0TrpIle: 0.0 ± 0.0
0.995TrpLys: 0.995 ± 1.173
0.995TrpLeu: 0.995 ± 0.808
0.995TrpMet: 0.995 ± 0.808
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.995TrpGln: 0.995 ± 0.735
1.99TrpArg: 1.99 ± 1.122
0.0TrpSer: 0.0 ± 0.0
0.995TrpThr: 0.995 ± 1.173
0.995TrpVal: 0.995 ± 0.808
0.0TrpTrp: 0.0 ± 0.0
0.995TrpTyr: 0.995 ± 0.735
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.975TyrAla: 4.975 ± 2.58
0.0TyrCys: 0.0 ± 0.0
1.99TyrAsp: 1.99 ± 1.616
1.99TyrGlu: 1.99 ± 1.253
1.99TyrPhe: 1.99 ± 1.262
2.985TyrGly: 2.985 ± 0.98
0.0TyrHis: 0.0 ± 0.0
5.97TyrIle: 5.97 ± 2.939
1.99TyrLys: 1.99 ± 0.773
6.965TyrLeu: 6.965 ± 2.154
2.985TyrMet: 2.985 ± 0.841
4.975TyrAsn: 4.975 ± 1.068
0.995TyrPro: 0.995 ± 0.735
0.0TyrGln: 0.0 ± 0.0
0.995TyrArg: 0.995 ± 0.808
4.975TyrSer: 4.975 ± 1.863
0.0TyrThr: 0.0 ± 0.0
2.985TyrVal: 2.985 ± 0.928
0.0TyrTrp: 0.0 ± 0.0
0.995TyrTyr: 0.995 ± 1.165
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1006 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski