Amino acid dipepetide frequency for Pontibacillus yanchengensis Y32

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.514AlaAla: 4.514 ± 0.08	0.538AlaCys: 0.538 ± 0.022	3.055AlaAsp: 3.055 ± 0.055	4.178AlaGlu: 4.178 ± 0.071	3.272AlaPhe: 3.272 ± 0.063	4.595AlaGly: 4.595 ± 0.078	1.35AlaHis: 1.35 ± 0.035	5.509AlaIle: 5.509 ± 0.083	4.085AlaLys: 4.085 ± 0.059	6.725AlaLeu: 6.725 ± 0.09	2.084AlaMet: 2.084 ± 0.047	2.77AlaAsn: 2.77 ± 0.042	2.046AlaPro: 2.046 ± 0.045	2.429AlaGln: 2.429 ± 0.05	2.408AlaArg: 2.408 ± 0.049	4.263AlaSer: 4.263 ± 0.062	3.582AlaThr: 3.582 ± 0.063	4.608AlaVal: 4.608 ± 0.064	0.611AlaTrp: 0.611 ± 0.025	2.419AlaTyr: 2.419 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.372CysAla: 0.372 ± 0.019	0.086CysCys: 0.086 ± 0.009	0.391CysAsp: 0.391 ± 0.019	0.425CysGlu: 0.425 ± 0.025	0.285CysPhe: 0.285 ± 0.015	0.574CysGly: 0.574 ± 0.024	0.185CysHis: 0.185 ± 0.012	0.457CysIle: 0.457 ± 0.022	0.347CysLys: 0.347 ± 0.017	0.58CysLeu: 0.58 ± 0.024	0.175CysMet: 0.175 ± 0.012	0.269CysAsn: 0.269 ± 0.015	0.33CysPro: 0.33 ± 0.021	0.209CysGln: 0.209 ± 0.012	0.222CysArg: 0.222 ± 0.015	0.42CysSer: 0.42 ± 0.019	0.35CysThr: 0.35 ± 0.02	0.373CysVal: 0.373 ± 0.019	0.054CysTrp: 0.054 ± 0.007	0.232CysTyr: 0.232 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.277AspAla: 3.277 ± 0.055	0.32AspCys: 0.32 ± 0.018	2.774AspAsp: 2.774 ± 0.057	4.929AspGlu: 4.929 ± 0.073	2.415AspPhe: 2.415 ± 0.048	3.34AspGly: 3.34 ± 0.062	1.297AspHis: 1.297 ± 0.033	4.147AspIle: 4.147 ± 0.069	3.086AspLys: 3.086 ± 0.053	4.861AspLeu: 4.861 ± 0.066	1.605AspMet: 1.605 ± 0.044	1.962AspAsn: 1.962 ± 0.042	2.022AspPro: 2.022 ± 0.042	2.608AspGln: 2.608 ± 0.051	2.256AspArg: 2.256 ± 0.042	2.806AspSer: 2.806 ± 0.052	2.682AspThr: 2.682 ± 0.046	4.161AspVal: 4.161 ± 0.073	0.684AspTrp: 0.684 ± 0.025	2.332AspTyr: 2.332 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	5.596GluAla: 5.596 ± 0.083	0.36GluCys: 0.36 ± 0.016	4.806GluAsp: 4.806 ± 0.07	8.416GluGlu: 8.416 ± 0.113	2.425GluPhe: 2.425 ± 0.047	4.906GluGly: 4.906 ± 0.07	1.866GluHis: 1.866 ± 0.045	4.812GluIle: 4.812 ± 0.067	6.066GluLys: 6.066 ± 0.079	6.76GluLeu: 6.76 ± 0.086	2.529GluMet: 2.529 ± 0.046	3.809GluAsn: 3.809 ± 0.065	2.083GluPro: 2.083 ± 0.047	4.164GluGln: 4.164 ± 0.07	3.543GluArg: 3.543 ± 0.068	3.892GluSer: 3.892 ± 0.067	4.089GluThr: 4.089 ± 0.061	5.529GluVal: 5.529 ± 0.073	0.947GluTrp: 0.947 ± 0.028	2.428GluTyr: 2.428 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	2.747PheAla: 2.747 ± 0.058	0.29PheCys: 0.29 ± 0.015	2.33PheAsp: 2.33 ± 0.05	2.894PheGlu: 2.894 ± 0.049	2.341PhePhe: 2.341 ± 0.06	3.237PheGly: 3.237 ± 0.057	1.114PheHis: 1.114 ± 0.029	3.757PheIle: 3.757 ± 0.068	2.195PheLys: 2.195 ± 0.044	4.57PheLeu: 4.57 ± 0.086	1.284PheMet: 1.284 ± 0.034	1.79PheAsn: 1.79 ± 0.037	1.747PhePro: 1.747 ± 0.045	1.829PheGln: 1.829 ± 0.042	1.516PheArg: 1.516 ± 0.037	3.188PheSer: 3.188 ± 0.061	2.729PheThr: 2.729 ± 0.056	3.08PheVal: 3.08 ± 0.058	0.496PheTrp: 0.496 ± 0.025	1.76PheTyr: 1.76 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.638GlyAla: 4.638 ± 0.084	0.55GlyCys: 0.55 ± 0.025	3.495GlyAsp: 3.495 ± 0.064	4.868GlyGlu: 4.868 ± 0.067	3.328GlyPhe: 3.328 ± 0.062	4.728GlyGly: 4.728 ± 0.091	1.336GlyHis: 1.336 ± 0.036	5.417GlyIle: 5.417 ± 0.078	4.424GlyLys: 4.424 ± 0.066	6.274GlyLeu: 6.274 ± 0.083	2.245GlyMet: 2.245 ± 0.047	2.705GlyAsn: 2.705 ± 0.054	1.727GlyPro: 1.727 ± 0.041	2.137GlyGln: 2.137 ± 0.047	2.448GlyArg: 2.448 ± 0.048	4.062GlySer: 4.062 ± 0.063	3.842GlyThr: 3.842 ± 0.068	5.265GlyVal: 5.265 ± 0.073	0.798GlyTrp: 0.798 ± 0.026	2.936GlyTyr: 2.936 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.423HisAla: 1.423 ± 0.038	0.188HisCys: 0.188 ± 0.013	1.192HisAsp: 1.192 ± 0.031	1.635HisGlu: 1.635 ± 0.04	1.176HisPhe: 1.176 ± 0.036	1.427HisGly: 1.427 ± 0.035	0.788HisHis: 0.788 ± 0.031	1.725HisIle: 1.725 ± 0.039	1.214HisLys: 1.214 ± 0.034	2.284HisLeu: 2.284 ± 0.054	0.612HisMet: 0.612 ± 0.022	0.961HisAsn: 0.961 ± 0.028	1.249HisPro: 1.249 ± 0.033	1.099HisGln: 1.099 ± 0.034	0.887HisArg: 0.887 ± 0.028	1.372HisSer: 1.372 ± 0.041	1.271HisThr: 1.271 ± 0.029	1.613HisVal: 1.613 ± 0.037	0.251HisTrp: 0.251 ± 0.016	1.028HisTyr: 1.028 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.377IleAla: 5.377 ± 0.092	0.52IleCys: 0.52 ± 0.02	4.049IleAsp: 4.049 ± 0.067	5.542IleGlu: 5.542 ± 0.086	3.043IlePhe: 3.043 ± 0.063	5.784IleGly: 5.784 ± 0.087	1.84IleHis: 1.84 ± 0.041	5.287IleIle: 5.287 ± 0.088	3.813IleLys: 3.813 ± 0.056	6.592IleLeu: 6.592 ± 0.087	1.756IleMet: 1.756 ± 0.044	3.06IleAsn: 3.06 ± 0.057	3.331IlePro: 3.331 ± 0.057	3.389IleGln: 3.389 ± 0.06	2.867IleArg: 2.867 ± 0.056	4.888IleSer: 4.888 ± 0.066	4.443IleThr: 4.443 ± 0.059	5.276IleVal: 5.276 ± 0.073	0.675IleTrp: 0.675 ± 0.027	2.358IleTyr: 2.358 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	4.196LysAla: 4.196 ± 0.058	0.275LysCys: 0.275 ± 0.017	3.812LysAsp: 3.812 ± 0.062	6.771LysGlu: 6.771 ± 0.086	1.56LysPhe: 1.56 ± 0.038	4.349LysGly: 4.349 ± 0.069	1.521LysHis: 1.521 ± 0.038	3.516LysIle: 3.516 ± 0.057	4.92LysLys: 4.92 ± 0.075	5.061LysLeu: 5.061 ± 0.069	1.9LysMet: 1.9 ± 0.042	2.941LysAsn: 2.941 ± 0.055	2.228LysPro: 2.228 ± 0.046	3.752LysGln: 3.752 ± 0.066	3.109LysArg: 3.109 ± 0.057	3.377LysSer: 3.377 ± 0.058	3.19LysThr: 3.19 ± 0.053	4.337LysVal: 4.337 ± 0.063	0.795LysTrp: 0.795 ± 0.027	1.858LysTyr: 1.858 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	6.654LeuAla: 6.654 ± 0.095	0.567LeuCys: 0.567 ± 0.024	4.938LeuAsp: 4.938 ± 0.076	6.612LeuGlu: 6.612 ± 0.098	4.809LeuPhe: 4.809 ± 0.085	6.202LeuGly: 6.202 ± 0.091	2.273LeuHis: 2.273 ± 0.047	6.619LeuIle: 6.619 ± 0.089	5.553LeuLys: 5.553 ± 0.079	9.631LeuLeu: 9.631 ± 0.123	2.527LeuMet: 2.527 ± 0.049	4.068LeuAsn: 4.068 ± 0.059	3.929LeuPro: 3.929 ± 0.058	4.078LeuGln: 4.078 ± 0.064	3.382LeuArg: 3.382 ± 0.06	6.817LeuSer: 6.817 ± 0.084	5.545LeuThr: 5.545 ± 0.072	5.989LeuVal: 5.989 ± 0.084	0.84LeuTrp: 0.84 ± 0.03	3.319LeuTyr: 3.319 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	1.995MetAla: 1.995 ± 0.043	0.144MetCys: 0.144 ± 0.012	1.651MetAsp: 1.651 ± 0.039	2.215MetGlu: 2.215 ± 0.046	1.168MetPhe: 1.168 ± 0.034	1.865MetGly: 1.865 ± 0.039	0.505MetHis: 0.505 ± 0.023	2.198MetIle: 2.198 ± 0.05	2.572MetLys: 2.572 ± 0.049	2.643MetLeu: 2.643 ± 0.045	0.957MetMet: 0.957 ± 0.033	1.78MetAsn: 1.78 ± 0.042	1.025MetPro: 1.025 ± 0.045	1.007MetGln: 1.007 ± 0.033	1.167MetArg: 1.167 ± 0.041	1.76MetSer: 1.76 ± 0.038	1.655MetThr: 1.655 ± 0.037	1.9MetVal: 1.9 ± 0.043	0.221MetTrp: 0.221 ± 0.012	0.896MetTyr: 0.896 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	2.643AsnAla: 2.643 ± 0.05	0.234AsnCys: 0.234 ± 0.014	2.416AsnAsp: 2.416 ± 0.047	3.85AsnGlu: 3.85 ± 0.06	1.479AsnPhe: 1.479 ± 0.04	3.154AsnGly: 3.154 ± 0.06	1.234AsnHis: 1.234 ± 0.038	3.156AsnIle: 3.156 ± 0.055	2.833AsnLys: 2.833 ± 0.055	3.711AsnLeu: 3.711 ± 0.065	1.267AsnMet: 1.267 ± 0.031	2.047AsnAsn: 2.047 ± 0.052	2.062AsnPro: 2.062 ± 0.039	2.509AsnGln: 2.509 ± 0.055	1.977AsnArg: 1.977 ± 0.04	2.26AsnSer: 2.26 ± 0.057	2.31AsnThr: 2.31 ± 0.048	3.324AsnVal: 3.324 ± 0.057	0.538AsnTrp: 0.538 ± 0.024	1.558AsnTyr: 1.558 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	2.027ProAla: 2.027 ± 0.046	0.203ProCys: 0.203 ± 0.017	2.104ProAsp: 2.104 ± 0.038	3.125ProGlu: 3.125 ± 0.058	2.118ProPhe: 2.118 ± 0.048	2.24ProGly: 2.24 ± 0.05	0.858ProHis: 0.858 ± 0.028	2.922ProIle: 2.922 ± 0.05	2.138ProLys: 2.138 ± 0.045	3.385ProLeu: 3.385 ± 0.064	0.925ProMet: 0.925 ± 0.032	1.836ProAsn: 1.836 ± 0.042	1.028ProPro: 1.028 ± 0.037	1.19ProGln: 1.19 ± 0.038	1.025ProArg: 1.025 ± 0.03	2.602ProSer: 2.602 ± 0.046	2.105ProThr: 2.105 ± 0.044	2.74ProVal: 2.74 ± 0.051	0.39ProTrp: 0.39 ± 0.019	1.595ProTyr: 1.595 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.947GlnAla: 2.947 ± 0.053	0.203GlnCys: 0.203 ± 0.014	2.253GlnAsp: 2.253 ± 0.041	3.832GlnGlu: 3.832 ± 0.066	1.748GlnPhe: 1.748 ± 0.041	2.539GlnGly: 2.539 ± 0.053	1.096GlnHis: 1.096 ± 0.031	2.568GlnIle: 2.568 ± 0.05	2.967GlnLys: 2.967 ± 0.053	4.345GlnLeu: 4.345 ± 0.071	1.304GlnMet: 1.304 ± 0.039	1.904GlnAsn: 1.904 ± 0.047	1.455GlnPro: 1.455 ± 0.04	2.684GlnGln: 2.684 ± 0.069	1.635GlnArg: 1.635 ± 0.046	2.81GlnSer: 2.81 ± 0.056	2.384GlnThr: 2.384 ± 0.045	2.721GlnVal: 2.721 ± 0.047	0.535GlnTrp: 0.535 ± 0.019	1.631GlnTyr: 1.631 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	2.291ArgAla: 2.291 ± 0.046	0.228ArgCys: 0.228 ± 0.014	2.083ArgAsp: 2.083 ± 0.049	3.129ArgGlu: 3.129 ± 0.056	1.844ArgPhe: 1.844 ± 0.047	2.222ArgGly: 2.222 ± 0.045	0.837ArgHis: 0.837 ± 0.034	2.841ArgIle: 2.841 ± 0.046	2.909ArgLys: 2.909 ± 0.061	3.684ArgLeu: 3.684 ± 0.056	1.286ArgMet: 1.286 ± 0.035	1.92ArgAsn: 1.92 ± 0.046	1.21ArgPro: 1.21 ± 0.034	1.453ArgGln: 1.453 ± 0.04	1.725ArgArg: 1.725 ± 0.04	2.254ArgSer: 2.254 ± 0.05	2.097ArgThr: 2.097 ± 0.046	2.615ArgVal: 2.615 ± 0.049	0.475ArgTrp: 0.475 ± 0.018	1.631ArgTyr: 1.631 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	3.415SerAla: 3.415 ± 0.067	0.386SerCys: 0.386 ± 0.02	2.919SerAsp: 2.919 ± 0.053	4.265SerGlu: 4.265 ± 0.071	3.431SerPhe: 3.431 ± 0.066	4.178SerGly: 4.178 ± 0.066	1.365SerHis: 1.365 ± 0.036	5.384SerIle: 5.384 ± 0.083	3.856SerLys: 3.856 ± 0.062	6.245SerLeu: 6.245 ± 0.083	1.923SerMet: 1.923 ± 0.037	2.858SerAsn: 2.858 ± 0.045	2.194SerPro: 2.194 ± 0.048	2.277SerGln: 2.277 ± 0.045	2.171SerArg: 2.171 ± 0.045	4.561SerSer: 4.561 ± 0.089	3.556SerThr: 3.556 ± 0.053	4.179SerVal: 4.179 ± 0.057	0.659SerTrp: 0.659 ± 0.023	2.485SerTyr: 2.485 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	3.454ThrAla: 3.454 ± 0.064	0.335ThrCys: 0.335 ± 0.018	2.731ThrAsp: 2.731 ± 0.049	3.563ThrGlu: 3.563 ± 0.06	2.974ThrPhe: 2.974 ± 0.052	3.951ThrGly: 3.951 ± 0.063	1.163ThrHis: 1.163 ± 0.038	4.795ThrIle: 4.795 ± 0.071	3.376ThrLys: 3.376 ± 0.056	5.585ThrLeu: 5.585 ± 0.075	1.491ThrMet: 1.491 ± 0.036	2.621ThrAsn: 2.621 ± 0.053	2.407ThrPro: 2.407 ± 0.041	1.82ThrGln: 1.82 ± 0.042	1.842ThrArg: 1.842 ± 0.045	3.631ThrSer: 3.631 ± 0.063	3.169ThrThr: 3.169 ± 0.064	3.951ThrVal: 3.951 ± 0.061	0.574ThrTrp: 0.574 ± 0.023	2.319ThrTyr: 2.319 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	4.726ValAla: 4.726 ± 0.065	0.533ValCys: 0.533 ± 0.023	3.926ValAsp: 3.926 ± 0.067	5.203ValGlu: 5.203 ± 0.072	3.046ValPhe: 3.046 ± 0.057	4.738ValGly: 4.738 ± 0.072	1.584ValHis: 1.584 ± 0.04	5.29ValIle: 5.29 ± 0.064	4.213ValLys: 4.213 ± 0.067	6.792ValLeu: 6.792 ± 0.091	2.021ValMet: 2.021 ± 0.047	3.03ValAsn: 3.03 ± 0.054	2.691ValPro: 2.691 ± 0.045	2.75ValGln: 2.75 ± 0.051	2.622ValArg: 2.622 ± 0.045	4.559ValSer: 4.559 ± 0.06	4.23ValThr: 4.23 ± 0.063	5.139ValVal: 5.139 ± 0.07	0.696ValTrp: 0.696 ± 0.026	2.319ValTyr: 2.319 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.57TrpAla: 0.57 ± 0.025	0.07TrpCys: 0.07 ± 0.007	0.568TrpAsp: 0.568 ± 0.024	0.746TrpGlu: 0.746 ± 0.024	0.594TrpPhe: 0.594 ± 0.023	0.695TrpGly: 0.695 ± 0.03	0.194TrpHis: 0.194 ± 0.015	0.901TrpIle: 0.901 ± 0.032	0.771TrpLys: 0.771 ± 0.028	1.21TrpLeu: 1.21 ± 0.034	0.403TrpMet: 0.403 ± 0.021	0.554TrpAsn: 0.554 ± 0.022	0.265TrpPro: 0.265 ± 0.015	0.361TrpGln: 0.361 ± 0.017	0.385TrpArg: 0.385 ± 0.018	0.642TrpSer: 0.642 ± 0.024	0.559TrpThr: 0.559 ± 0.021	0.772TrpVal: 0.772 ± 0.028	0.165TrpTrp: 0.165 ± 0.011	0.417TrpTyr: 0.417 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.181TyrAla: 2.181 ± 0.048	0.304TyrCys: 0.304 ± 0.016	2.072TyrAsp: 2.072 ± 0.044	2.829TyrGlu: 2.829 ± 0.052	1.839TyrPhe: 1.839 ± 0.046	2.5TyrGly: 2.5 ± 0.054	0.989TyrHis: 0.989 ± 0.028	2.591TyrIle: 2.591 ± 0.047	2.131TyrLys: 2.131 ± 0.046	3.415TyrLeu: 3.415 ± 0.059	1.029TyrMet: 1.029 ± 0.03	1.678TyrAsn: 1.678 ± 0.038	1.525TyrPro: 1.525 ± 0.042	1.813TyrGln: 1.813 ± 0.04	1.546TyrArg: 1.546 ± 0.041	2.144TyrSer: 2.144 ± 0.039	1.964TyrThr: 1.964 ± 0.042	2.534TyrVal: 2.534 ± 0.05	0.438TyrTrp: 0.438 ± 0.023	1.553TyrTyr: 1.553 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3964 proteins (1154180 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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