Amino acid dipepetide frequency for Changjiang sobemo-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.359AlaAla: 10.359 ± 0.451
0.691AlaCys: 0.691 ± 0.692
6.906AlaAsp: 6.906 ± 1.306
5.525AlaGlu: 5.525 ± 1.971
2.762AlaPhe: 2.762 ± 1.722
5.525AlaGly: 5.525 ± 0.092
2.072AlaHis: 2.072 ± 1.17
7.597AlaIle: 7.597 ± 0.812
10.359AlaLys: 10.359 ± 3.944
4.834AlaLeu: 4.834 ± 1.303
2.072AlaMet: 2.072 ± 1.063
4.144AlaAsn: 4.144 ± 1.344
3.453AlaPro: 3.453 ± 1.65
2.072AlaGln: 2.072 ± 0.703
2.762AlaArg: 2.762 ± 1.045
5.525AlaSer: 5.525 ± 1.012
5.525AlaThr: 5.525 ± 1.975
8.978AlaVal: 8.978 ± 1.585
0.691AlaTrp: 0.691 ± 0.736
0.691AlaTyr: 0.691 ± 0.736
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.691CysPhe: 0.691 ± 0.736
0.691CysGly: 0.691 ± 0.736
0.691CysHis: 0.691 ± 0.432
0.691CysIle: 0.691 ± 0.736
0.0CysLys: 0.0 ± 0.0
2.762CysLeu: 2.762 ± 1.074
0.691CysMet: 0.691 ± 0.432
0.691CysAsn: 0.691 ± 0.692
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.691CysArg: 0.691 ± 0.736
2.762CysSer: 2.762 ± 0.046
1.381CysThr: 1.381 ± 0.861
1.381CysVal: 1.381 ± 0.547
0.0CysTrp: 0.0 ± 0.0
0.691CysTyr: 0.691 ± 0.736
0.0CysXaa: 0.0 ± 0.0
Asp
3.453AspAla: 3.453 ± 1.259
0.691AspCys: 0.691 ± 0.736
3.453AspAsp: 3.453 ± 1.259
3.453AspGlu: 3.453 ± 1.259
2.072AspPhe: 2.072 ± 1.297
4.834AspGly: 4.834 ± 1.357
0.0AspHis: 0.0 ± 0.0
0.691AspIle: 0.691 ± 0.432
2.762AspLys: 2.762 ± 1.185
3.453AspLeu: 3.453 ± 2.71
2.762AspMet: 2.762 ± 0.046
1.381AspAsn: 1.381 ± 0.861
6.215AspPro: 6.215 ± 2.483
2.762AspGln: 2.762 ± 1.031
0.691AspArg: 0.691 ± 0.432
2.762AspSer: 2.762 ± 0.046
0.691AspThr: 0.691 ± 0.736
3.453AspVal: 3.453 ± 0.44
2.762AspTrp: 2.762 ± 1.982
3.453AspTyr: 3.453 ± 0.77
0.0AspXaa: 0.0 ± 0.0
Glu
11.05GluAla: 11.05 ± 3.924
2.072GluCys: 2.072 ± 2.208
2.072GluAsp: 2.072 ± 1.297
7.597GluGlu: 7.597 ± 3.032
2.072GluPhe: 2.072 ± 0.731
2.762GluGly: 2.762 ± 1.031
0.691GluHis: 0.691 ± 0.736
2.762GluIle: 2.762 ± 1.045
4.144GluLys: 4.144 ± 1.462
7.597GluLeu: 7.597 ± 2.233
2.072GluMet: 2.072 ± 0.703
2.072GluAsn: 2.072 ± 1.297
2.762GluPro: 2.762 ± 0.046
1.381GluGln: 1.381 ± 0.593
4.834GluArg: 4.834 ± 0.432
3.453GluSer: 3.453 ± 1.422
2.072GluThr: 2.072 ± 0.703
2.072GluVal: 2.072 ± 0.703
1.381GluTrp: 1.381 ± 0.593
2.072GluTyr: 2.072 ± 0.731
0.0GluXaa: 0.0 ± 0.0
Phe
4.144PheAla: 4.144 ± 0.638
1.381PheCys: 1.381 ± 1.472
2.762PheAsp: 2.762 ± 1.73
2.762PheGlu: 2.762 ± 0.046
0.691PhePhe: 0.691 ± 0.432
2.072PheGly: 2.072 ± 0.703
0.0PheHis: 0.0 ± 0.0
0.691PheIle: 0.691 ± 0.692
0.691PheLys: 0.691 ± 0.692
2.072PheLeu: 2.072 ± 0.703
1.381PheMet: 1.381 ± 0.593
2.072PheAsn: 2.072 ± 2.075
0.691PhePro: 0.691 ± 0.692
0.691PheGln: 0.691 ± 0.692
2.762PheArg: 2.762 ± 1.074
0.0PheSer: 0.0 ± 0.0
3.453PheThr: 3.453 ± 0.77
1.381PheVal: 1.381 ± 0.861
0.0PheTrp: 0.0 ± 0.0
2.762PheTyr: 2.762 ± 1.73
0.0PheXaa: 0.0 ± 0.0
Gly
6.906GlyAla: 6.906 ± 2.295
0.0GlyCys: 0.0 ± 0.0
4.144GlyAsp: 4.144 ± 0.638
0.691GlyGlu: 0.691 ± 0.432
3.453GlyPhe: 3.453 ± 1.416
3.453GlyGly: 3.453 ± 1.65
0.691GlyHis: 0.691 ± 0.692
4.144GlyIle: 4.144 ± 0.502
3.453GlyLys: 3.453 ± 0.44
3.453GlyLeu: 3.453 ± 1.183
0.0GlyMet: 0.0 ± 0.0
2.072GlyAsn: 2.072 ± 1.17
2.072GlyPro: 2.072 ± 1.17
2.762GlyGln: 2.762 ± 1.031
2.072GlyArg: 2.072 ± 1.264
8.978GlySer: 8.978 ± 2.485
5.525GlyThr: 5.525 ± 1.975
3.453GlyVal: 3.453 ± 0.653
0.691GlyTrp: 0.691 ± 0.736
4.834GlyTyr: 4.834 ± 2.358
0.0GlyXaa: 0.0 ± 0.0
His
1.381HisAla: 1.381 ± 0.593
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.381HisGlu: 1.381 ± 1.383
0.0HisPhe: 0.0 ± 0.0
0.691HisGly: 0.691 ± 0.692
0.0HisHis: 0.0 ± 0.0
0.691HisIle: 0.691 ± 0.692
0.0HisLys: 0.0 ± 0.0
2.072HisLeu: 2.072 ± 0.703
0.691HisMet: 0.691 ± 0.432
0.0HisAsn: 0.0 ± 0.0
0.691HisPro: 0.691 ± 0.736
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.381HisThr: 1.381 ± 0.593
0.691HisVal: 0.691 ± 0.432
0.0HisTrp: 0.0 ± 0.0
0.691HisTyr: 0.691 ± 0.432
0.0HisXaa: 0.0 ± 0.0
Ile
5.525IleAla: 5.525 ± 1.975
0.691IleCys: 0.691 ± 0.692
2.072IleAsp: 2.072 ± 0.43
3.453IleGlu: 3.453 ± 1.259
0.0IlePhe: 0.0 ± 0.0
2.762IleGly: 2.762 ± 1.094
0.691IleHis: 0.691 ± 0.432
0.0IleIle: 0.0 ± 0.0
3.453IleLys: 3.453 ± 0.77
2.762IleLeu: 2.762 ± 1.045
1.381IleMet: 1.381 ± 0.547
2.072IleAsn: 2.072 ± 1.297
3.453IlePro: 3.453 ± 1.422
2.072IleGln: 2.072 ± 0.703
5.525IleArg: 5.525 ± 3.965
5.525IleSer: 5.525 ± 0.092
1.381IleThr: 1.381 ± 0.865
4.144IleVal: 4.144 ± 1.641
0.0IleTrp: 0.0 ± 0.0
1.381IleTyr: 1.381 ± 0.865
0.0IleXaa: 0.0 ± 0.0
Lys
4.834LysAla: 4.834 ± 1.125
1.381LysCys: 1.381 ± 1.383
5.525LysAsp: 5.525 ± 1.231
4.144LysGlu: 4.144 ± 1.824
2.072LysPhe: 2.072 ± 0.731
1.381LysGly: 1.381 ± 0.865
0.0LysHis: 0.0 ± 0.0
2.762LysIle: 2.762 ± 1.185
4.834LysLys: 4.834 ± 1.704
9.669LysLeu: 9.669 ± 2.82
2.072LysMet: 2.072 ± 0.43
2.072LysAsn: 2.072 ± 0.43
2.072LysPro: 2.072 ± 1.297
3.453LysGln: 3.453 ± 1.422
5.525LysArg: 5.525 ± 1.735
8.287LysSer: 8.287 ± 4.003
3.453LysThr: 3.453 ± 1.69
3.453LysVal: 3.453 ± 0.44
0.691LysTrp: 0.691 ± 0.432
2.762LysTyr: 2.762 ± 1.185
0.0LysXaa: 0.0 ± 0.0
Leu
8.287LeuAla: 8.287 ± 1.003
0.691LeuCys: 0.691 ± 0.736
3.453LeuAsp: 3.453 ± 0.44
7.597LeuGlu: 7.597 ± 2.456
4.144LeuPhe: 4.144 ± 0.502
4.144LeuGly: 4.144 ± 0.502
0.691LeuHis: 0.691 ± 0.432
4.834LeuIle: 4.834 ± 2.242
6.906LeuLys: 6.906 ± 4.324
9.669LeuLeu: 9.669 ± 3.502
2.072LeuMet: 2.072 ± 2.572
4.144LeuAsn: 4.144 ± 1.824
2.762LeuPro: 2.762 ± 1.045
2.762LeuGln: 2.762 ± 1.031
4.834LeuArg: 4.834 ± 1.303
5.525LeuSer: 5.525 ± 2.188
2.762LeuThr: 2.762 ± 1.045
4.834LeuVal: 4.834 ± 1.826
1.381LeuTrp: 1.381 ± 0.593
4.834LeuTyr: 4.834 ± 0.432
0.0LeuXaa: 0.0 ± 0.0
Met
2.072MetAla: 2.072 ± 0.43
0.0MetCys: 0.0 ± 0.0
0.691MetAsp: 0.691 ± 0.692
1.381MetGlu: 1.381 ± 0.547
2.072MetPhe: 2.072 ± 1.377
2.072MetGly: 2.072 ± 2.075
0.0MetHis: 0.0 ± 0.0
0.691MetIle: 0.691 ± 0.736
2.762MetLys: 2.762 ± 0.987
2.072MetLeu: 2.072 ± 0.731
0.0MetMet: 0.0 ± 0.0
1.381MetAsn: 1.381 ± 0.593
2.762MetPro: 2.762 ± 1.031
0.0MetGln: 0.0 ± 0.0
2.072MetArg: 2.072 ± 1.17
2.072MetSer: 2.072 ± 1.17
1.381MetThr: 1.381 ± 0.865
2.762MetVal: 2.762 ± 0.046
0.691MetTrp: 0.691 ± 0.432
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.453AsnAla: 3.453 ± 0.653
0.691AsnCys: 0.691 ± 0.736
2.072AsnAsp: 2.072 ± 1.264
4.834AsnGlu: 4.834 ± 1.751
1.381AsnPhe: 1.381 ± 0.547
4.834AsnGly: 4.834 ± 2.151
0.0AsnHis: 0.0 ± 0.0
2.762AsnIle: 2.762 ± 0.046
3.453AsnLys: 3.453 ± 1.416
4.834AsnLeu: 4.834 ± 1.125
1.381AsnMet: 1.381 ± 0.769
2.762AsnAsn: 2.762 ± 1.094
1.381AsnPro: 1.381 ± 1.383
1.381AsnGln: 1.381 ± 0.865
0.691AsnArg: 0.691 ± 0.692
2.072AsnSer: 2.072 ± 0.703
4.144AsnThr: 4.144 ± 2.755
2.762AsnVal: 2.762 ± 0.046
0.0AsnTrp: 0.0 ± 0.0
0.691AsnTyr: 0.691 ± 0.692
0.0AsnXaa: 0.0 ± 0.0
Pro
4.144ProAla: 4.144 ± 1.641
1.381ProCys: 1.381 ± 0.547
2.762ProAsp: 2.762 ± 1.074
2.762ProGlu: 2.762 ± 1.73
0.691ProPhe: 0.691 ± 0.692
4.834ProGly: 4.834 ± 0.432
1.381ProHis: 1.381 ± 0.593
0.691ProIle: 0.691 ± 0.432
0.691ProLys: 0.691 ± 0.432
2.072ProLeu: 2.072 ± 0.703
2.072ProMet: 2.072 ± 1.17
0.691ProAsn: 0.691 ± 0.736
1.381ProPro: 1.381 ± 0.865
0.691ProGln: 0.691 ± 0.432
4.144ProArg: 4.144 ± 1.344
4.834ProSer: 4.834 ± 2.036
3.453ProThr: 3.453 ± 1.69
6.215ProVal: 6.215 ± 1.404
1.381ProTrp: 1.381 ± 0.593
1.381ProTyr: 1.381 ± 0.593
0.0ProXaa: 0.0 ± 0.0
Gln
2.072GlnAla: 2.072 ± 1.297
0.0GlnCys: 0.0 ± 0.0
0.691GlnAsp: 0.691 ± 0.736
1.381GlnGlu: 1.381 ± 0.865
0.0GlnPhe: 0.0 ± 0.0
2.072GlnGly: 2.072 ± 0.43
0.0GlnHis: 0.0 ± 0.0
2.762GlnIle: 2.762 ± 1.031
2.762GlnLys: 2.762 ± 1.185
2.762GlnLeu: 2.762 ± 1.094
0.691GlnMet: 0.691 ± 0.692
2.072GlnAsn: 2.072 ± 0.731
2.072GlnPro: 2.072 ± 0.43
0.691GlnGln: 0.691 ± 0.432
4.144GlnArg: 4.144 ± 1.406
1.381GlnSer: 1.381 ± 0.547
2.072GlnThr: 2.072 ± 1.17
0.691GlnVal: 0.691 ± 0.692
0.0GlnTrp: 0.0 ± 0.0
0.691GlnTyr: 0.691 ± 0.432
0.0GlnXaa: 0.0 ± 0.0
Arg
2.762ArgAla: 2.762 ± 0.046
1.381ArgCys: 1.381 ± 0.593
2.762ArgAsp: 2.762 ± 1.73
2.762ArgGlu: 2.762 ± 1.045
1.381ArgPhe: 1.381 ± 0.547
4.144ArgGly: 4.144 ± 1.823
0.691ArgHis: 0.691 ± 0.736
1.381ArgIle: 1.381 ± 0.593
3.453ArgLys: 3.453 ± 0.44
4.834ArgLeu: 4.834 ± 2.412
1.381ArgMet: 1.381 ± 0.547
4.144ArgAsn: 4.144 ± 0.86
3.453ArgPro: 3.453 ± 0.653
2.072ArgGln: 2.072 ± 2.075
2.072ArgArg: 2.072 ± 1.445
3.453ArgSer: 3.453 ± 0.77
2.072ArgThr: 2.072 ± 1.17
3.453ArgVal: 3.453 ± 1.259
0.0ArgTrp: 0.0 ± 0.0
4.144ArgTyr: 4.144 ± 0.871
0.0ArgXaa: 0.0 ± 0.0
Ser
10.359SerAla: 10.359 ± 2.548
0.691SerCys: 0.691 ± 0.432
2.762SerAsp: 2.762 ± 1.982
6.215SerGlu: 6.215 ± 2.44
2.072SerPhe: 2.072 ± 0.731
4.834SerGly: 4.834 ± 0.432
0.691SerHis: 0.691 ± 0.692
4.834SerIle: 4.834 ± 1.711
6.906SerLys: 6.906 ± 0.88
6.906SerLeu: 6.906 ± 1.815
0.691SerMet: 0.691 ± 0.432
2.762SerAsn: 2.762 ± 1.842
4.144SerPro: 4.144 ± 1.641
1.381SerGln: 1.381 ± 0.861
0.691SerArg: 0.691 ± 0.432
11.05SerSer: 11.05 ± 2.935
4.834SerThr: 4.834 ± 1.305
7.597SerVal: 7.597 ± 1.337
1.381SerTrp: 1.381 ± 0.861
2.072SerTyr: 2.072 ± 1.445
0.0SerXaa: 0.0 ± 0.0
Thr
2.762ThrAla: 2.762 ± 2.003
0.691ThrCys: 0.691 ± 0.432
4.144ThrAsp: 4.144 ± 1.506
2.072ThrGlu: 2.072 ± 0.43
2.762ThrPhe: 2.762 ± 1.722
2.762ThrGly: 2.762 ± 1.031
0.0ThrHis: 0.0 ± 0.0
4.834ThrIle: 4.834 ± 1.125
2.072ThrLys: 2.072 ± 1.377
4.834ThrLeu: 4.834 ± 1.305
2.072ThrMet: 2.072 ± 1.17
2.072ThrAsn: 2.072 ± 0.43
2.072ThrPro: 2.072 ± 0.43
0.0ThrGln: 0.0 ± 0.0
2.072ThrArg: 2.072 ± 0.703
5.525ThrSer: 5.525 ± 1.049
7.597ThrThr: 7.597 ± 3.109
5.525ThrVal: 5.525 ± 1.799
0.691ThrTrp: 0.691 ± 0.736
2.762ThrTyr: 2.762 ± 0.046
0.0ThrXaa: 0.0 ± 0.0
Val
5.525ValAla: 5.525 ± 2.661
0.691ValCys: 0.691 ± 0.432
3.453ValAsp: 3.453 ± 2.191
4.144ValGlu: 4.144 ± 1.462
1.381ValPhe: 1.381 ± 0.593
3.453ValGly: 3.453 ± 0.653
0.691ValHis: 0.691 ± 0.432
2.072ValIle: 2.072 ± 1.297
8.978ValLys: 8.978 ± 2.164
6.215ValLeu: 6.215 ± 0.806
1.381ValMet: 1.381 ± 1.383
4.144ValAsn: 4.144 ± 1.641
4.834ValPro: 4.834 ± 1.303
2.072ValGln: 2.072 ± 1.445
2.762ValArg: 2.762 ± 1.031
5.525ValSer: 5.525 ± 1.975
2.762ValThr: 2.762 ± 0.046
3.453ValVal: 3.453 ± 1.416
1.381ValTrp: 1.381 ± 1.383
3.453ValTyr: 3.453 ± 1.259
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.381TrpAsp: 1.381 ± 1.472
1.381TrpGlu: 1.381 ± 0.865
0.691TrpPhe: 0.691 ± 0.692
1.381TrpGly: 1.381 ± 0.865
0.0TrpHis: 0.0 ± 0.0
0.691TrpIle: 0.691 ± 0.736
0.0TrpLys: 0.0 ± 0.0
1.381TrpLeu: 1.381 ± 0.593
0.691TrpMet: 0.691 ± 0.736
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.691TrpGln: 0.691 ± 0.692
1.381TrpArg: 1.381 ± 0.547
1.381TrpSer: 1.381 ± 1.472
0.691TrpThr: 0.691 ± 0.736
0.691TrpVal: 0.691 ± 0.736
0.0TrpTrp: 0.0 ± 0.0
0.691TrpTyr: 0.691 ± 0.736
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.453TyrAla: 3.453 ± 0.77
0.691TyrCys: 0.691 ± 0.432
0.691TyrAsp: 0.691 ± 0.432
3.453TyrGlu: 3.453 ± 0.44
2.072TyrPhe: 2.072 ± 0.703
4.144TyrGly: 4.144 ± 0.502
1.381TyrHis: 1.381 ± 0.547
2.762TyrIle: 2.762 ± 1.094
2.762TyrLys: 2.762 ± 1.982
2.762TyrLeu: 2.762 ± 0.046
0.691TyrMet: 0.691 ± 0.736
4.834TyrAsn: 4.834 ± 2.242
1.381TyrPro: 1.381 ± 0.593
2.072TyrGln: 2.072 ± 0.731
2.072TyrArg: 2.072 ± 0.731
2.762TyrSer: 2.762 ± 0.046
0.691TyrThr: 0.691 ± 0.736
1.381TyrVal: 1.381 ± 0.593
0.0TyrTrp: 0.0 ± 0.0
1.381TyrTyr: 1.381 ± 0.547
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1449 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski