Amino acid dipepetide frequency for Phomopsis vexans RNA virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.394AlaAla: 15.394 ± 2.784
0.641AlaCys: 0.641 ± 0.425
6.414AlaAsp: 6.414 ± 3.541
3.849AlaGlu: 3.849 ± 0.819
4.49AlaPhe: 4.49 ± 1.353
12.187AlaGly: 12.187 ± 2.313
1.924AlaHis: 1.924 ± 1.322
3.207AlaIle: 3.207 ± 0.394
4.49AlaLys: 4.49 ± 0.379
10.263AlaLeu: 10.263 ± 0.99
1.283AlaMet: 1.283 ± 0.85
7.697AlaAsn: 7.697 ± 1.825
5.131AlaPro: 5.131 ± 1.794
3.849AlaGln: 3.849 ± 0.913
5.131AlaArg: 5.131 ± 0.804
7.056AlaSer: 7.056 ± 2.25
4.49AlaThr: 4.49 ± 0.487
10.263AlaVal: 10.263 ± 0.99
2.566AlaTrp: 2.566 ± 0.835
2.566AlaTyr: 2.566 ± 0.835
0.0AlaXaa: 0.0 ± 0.0
Cys
1.924CysAla: 1.924 ± 0.456
0.0CysCys: 0.0 ± 0.0
1.924CysAsp: 1.924 ± 0.456
0.0CysGlu: 0.0 ± 0.0
0.641CysPhe: 0.641 ± 0.425
1.924CysGly: 1.924 ± 1.276
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.283CysLeu: 1.283 ± 0.85
0.0CysMet: 0.0 ± 0.0
1.283CysAsn: 1.283 ± 0.85
1.283CysPro: 1.283 ± 0.85
0.0CysGln: 0.0 ± 0.0
1.283CysArg: 1.283 ± 0.85
0.0CysSer: 0.0 ± 0.0
1.283CysThr: 1.283 ± 0.016
1.283CysVal: 1.283 ± 0.881
0.0CysTrp: 0.0 ± 0.0
0.641CysTyr: 0.641 ± 0.425
0.0CysXaa: 0.0 ± 0.0
Asp
10.263AspAla: 10.263 ± 3.588
0.641AspCys: 0.641 ± 0.425
3.849AspAsp: 3.849 ± 1.685
5.131AspGlu: 5.131 ± 1.794
3.207AspPhe: 3.207 ± 1.26
1.924AspGly: 1.924 ± 0.456
1.283AspHis: 1.283 ± 0.881
3.207AspIle: 3.207 ± 1.26
0.641AspLys: 0.641 ± 0.425
5.773AspLeu: 5.773 ± 0.363
1.283AspMet: 1.283 ± 0.85
1.283AspAsn: 1.283 ± 0.881
4.49AspPro: 4.49 ± 1.244
1.283AspGln: 1.283 ± 0.016
5.131AspArg: 5.131 ± 0.062
4.49AspSer: 4.49 ± 1.244
1.283AspThr: 1.283 ± 0.85
2.566AspVal: 2.566 ± 0.897
0.0AspTrp: 0.0 ± 0.0
2.566AspTyr: 2.566 ± 0.835
0.0AspXaa: 0.0 ± 0.0
Glu
3.207GluAla: 3.207 ± 0.472
1.283GluCys: 1.283 ± 0.85
4.49GluAsp: 4.49 ± 0.379
3.207GluGlu: 3.207 ± 0.472
1.283GluPhe: 1.283 ± 0.016
3.207GluGly: 3.207 ± 0.472
1.924GluHis: 1.924 ± 0.41
1.924GluIle: 1.924 ± 0.41
1.283GluLys: 1.283 ± 0.016
5.131GluLeu: 5.131 ± 1.67
0.641GluMet: 0.641 ± 0.441
0.0GluAsn: 0.0 ± 0.0
1.924GluPro: 1.924 ± 1.322
2.566GluGln: 2.566 ± 0.897
3.849GluArg: 3.849 ± 0.819
2.566GluSer: 2.566 ± 0.031
1.924GluThr: 1.924 ± 0.41
1.924GluVal: 1.924 ± 0.41
1.283GluTrp: 1.283 ± 0.016
1.283GluTyr: 1.283 ± 0.016
0.0GluXaa: 0.0 ± 0.0
Phe
1.924PheAla: 1.924 ± 0.456
0.0PheCys: 0.0 ± 0.0
1.283PheAsp: 1.283 ± 0.881
3.207PheGlu: 3.207 ± 0.472
0.0PhePhe: 0.0 ± 0.0
3.849PheGly: 3.849 ± 0.047
0.0PheHis: 0.0 ± 0.0
0.641PheIle: 0.641 ± 0.441
0.641PheLys: 0.641 ± 0.441
1.283PheLeu: 1.283 ± 0.85
0.0PheMet: 0.0 ± 0.0
0.641PheAsn: 0.641 ± 0.425
1.924PhePro: 1.924 ± 1.276
0.641PheGln: 0.641 ± 0.441
1.924PheArg: 1.924 ± 1.322
2.566PheSer: 2.566 ± 0.031
2.566PheThr: 2.566 ± 0.031
3.207PheVal: 3.207 ± 1.26
0.641PheTrp: 0.641 ± 0.441
0.641PheTyr: 0.641 ± 0.441
0.0PheXaa: 0.0 ± 0.0
Gly
9.622GlyAla: 9.622 ± 3.147
1.283GlyCys: 1.283 ± 0.85
8.339GlyAsp: 8.339 ± 2.266
1.924GlyGlu: 1.924 ± 0.41
2.566GlyPhe: 2.566 ± 0.835
8.98GlyGly: 8.98 ± 4.438
4.49GlyHis: 4.49 ± 1.244
1.924GlyIle: 1.924 ± 0.456
3.207GlyLys: 3.207 ± 2.126
6.414GlyLeu: 6.414 ± 3.541
1.283GlyMet: 1.283 ± 0.85
1.924GlyAsn: 1.924 ± 0.41
4.49GlyPro: 4.49 ± 1.353
2.566GlyGln: 2.566 ± 0.897
7.697GlyArg: 7.697 ± 0.959
3.849GlySer: 3.849 ± 0.047
6.414GlyThr: 6.414 ± 1.81
8.98GlyVal: 8.98 ± 2.707
1.924GlyTrp: 1.924 ± 0.456
1.924GlyTyr: 1.924 ± 1.276
0.0GlyXaa: 0.0 ± 0.0
His
1.924HisAla: 1.924 ± 0.41
1.924HisCys: 1.924 ± 0.456
1.283HisAsp: 1.283 ± 0.016
0.641HisGlu: 0.641 ± 0.425
0.0HisPhe: 0.0 ± 0.0
2.566HisGly: 2.566 ± 0.031
1.283HisHis: 1.283 ± 0.016
1.283HisIle: 1.283 ± 0.016
1.283HisLys: 1.283 ± 0.016
1.924HisLeu: 1.924 ± 0.41
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.641HisPro: 0.641 ± 0.425
0.641HisGln: 0.641 ± 0.441
2.566HisArg: 2.566 ± 0.835
1.283HisSer: 1.283 ± 0.016
1.924HisThr: 1.924 ± 0.41
3.207HisVal: 3.207 ± 1.26
0.641HisTrp: 0.641 ± 0.425
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.207IleAla: 3.207 ± 0.394
0.641IleCys: 0.641 ± 0.441
0.641IleAsp: 0.641 ± 0.425
1.924IleGlu: 1.924 ± 0.41
1.283IlePhe: 1.283 ± 0.881
1.924IleGly: 1.924 ± 0.456
0.0IleHis: 0.0 ± 0.0
0.641IleIle: 0.641 ± 0.425
1.283IleLys: 1.283 ± 0.85
3.207IleLeu: 3.207 ± 1.26
0.0IleMet: 0.0 ± 0.0
1.924IleAsn: 1.924 ± 0.456
2.566IlePro: 2.566 ± 0.897
0.641IleGln: 0.641 ± 0.425
2.566IleArg: 2.566 ± 0.031
3.849IleSer: 3.849 ± 0.913
1.924IleThr: 1.924 ± 0.41
2.566IleVal: 2.566 ± 0.897
0.0IleTrp: 0.0 ± 0.0
1.924IleTyr: 1.924 ± 1.276
0.0IleXaa: 0.0 ± 0.0
Lys
3.207LysAla: 3.207 ± 1.26
0.0LysCys: 0.0 ± 0.0
1.283LysAsp: 1.283 ± 0.85
1.283LysGlu: 1.283 ± 0.85
0.0LysPhe: 0.0 ± 0.0
1.283LysGly: 1.283 ± 0.85
1.924LysHis: 1.924 ± 0.41
0.641LysIle: 0.641 ± 0.441
0.641LysLys: 0.641 ± 0.425
2.566LysLeu: 2.566 ± 1.701
0.641LysMet: 0.641 ± 0.441
1.283LysAsn: 1.283 ± 0.016
0.641LysPro: 0.641 ± 0.425
1.283LysGln: 1.283 ± 0.85
4.49LysArg: 4.49 ± 2.11
1.924LysSer: 1.924 ± 0.41
2.566LysThr: 2.566 ± 0.835
0.641LysVal: 0.641 ± 0.441
0.0LysTrp: 0.0 ± 0.0
1.924LysTyr: 1.924 ± 0.456
0.0LysXaa: 0.0 ± 0.0
Leu
12.187LeuAla: 12.187 ± 0.285
0.641LeuCys: 0.641 ± 0.425
4.49LeuAsp: 4.49 ± 0.379
7.697LeuGlu: 7.697 ± 3.37
0.0LeuPhe: 0.0 ± 0.0
6.414LeuGly: 6.414 ± 0.944
1.283LeuHis: 1.283 ± 0.85
2.566LeuIle: 2.566 ± 0.031
2.566LeuLys: 2.566 ± 0.835
8.339LeuLeu: 8.339 ± 4.662
1.924LeuMet: 1.924 ± 1.08
3.207LeuAsn: 3.207 ± 0.472
3.849LeuPro: 3.849 ± 1.779
2.566LeuGln: 2.566 ± 0.835
11.546LeuArg: 11.546 ± 0.726
5.131LeuSer: 5.131 ± 0.062
7.056LeuThr: 7.056 ± 0.347
3.849LeuVal: 3.849 ± 1.685
0.641LeuTrp: 0.641 ± 0.441
1.283LeuTyr: 1.283 ± 0.016
0.0LeuXaa: 0.0 ± 0.0
Met
3.849MetAla: 3.849 ± 0.819
0.0MetCys: 0.0 ± 0.0
1.924MetAsp: 1.924 ± 0.456
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.641MetIle: 0.641 ± 0.425
0.641MetLys: 0.641 ± 0.425
2.566MetLeu: 2.566 ± 0.835
1.283MetMet: 1.283 ± 0.016
0.641MetAsn: 0.641 ± 0.425
1.283MetPro: 1.283 ± 0.85
0.0MetGln: 0.0 ± 0.0
1.283MetArg: 1.283 ± 0.016
1.283MetSer: 1.283 ± 0.85
0.641MetThr: 0.641 ± 0.425
3.849MetVal: 3.849 ± 1.685
0.0MetTrp: 0.0 ± 0.0
0.641MetTyr: 0.641 ± 0.425
0.0MetXaa: 0.0 ± 0.0
Asn
2.566AsnAla: 2.566 ± 1.763
0.0AsnCys: 0.0 ± 0.0
1.283AsnAsp: 1.283 ± 0.881
0.641AsnGlu: 0.641 ± 0.441
1.924AsnPhe: 1.924 ± 1.322
3.207AsnGly: 3.207 ± 1.338
0.0AsnHis: 0.0 ± 0.0
0.641AsnIle: 0.641 ± 0.425
1.283AsnLys: 1.283 ± 0.85
2.566AsnLeu: 2.566 ± 0.031
0.641AsnMet: 0.641 ± 0.425
0.641AsnAsn: 0.641 ± 0.425
3.207AsnPro: 3.207 ± 0.472
0.641AsnGln: 0.641 ± 0.441
1.924AsnArg: 1.924 ± 0.456
3.849AsnSer: 3.849 ± 0.819
1.924AsnThr: 1.924 ± 0.41
0.641AsnVal: 0.641 ± 0.441
1.283AsnTrp: 1.283 ± 0.85
1.924AsnTyr: 1.924 ± 0.41
0.0AsnXaa: 0.0 ± 0.0
Pro
8.339ProAla: 8.339 ± 3.998
0.641ProCys: 0.641 ± 0.441
3.849ProAsp: 3.849 ± 1.685
0.641ProGlu: 0.641 ± 0.441
0.641ProPhe: 0.641 ± 0.425
5.131ProGly: 5.131 ± 1.794
1.283ProHis: 1.283 ± 0.85
2.566ProIle: 2.566 ± 1.763
2.566ProLys: 2.566 ± 1.701
5.773ProLeu: 5.773 ± 1.229
1.283ProMet: 1.283 ± 0.016
1.283ProAsn: 1.283 ± 0.016
8.339ProPro: 8.339 ± 3.132
2.566ProGln: 2.566 ± 0.897
3.207ProArg: 3.207 ± 0.472
5.773ProSer: 5.773 ± 0.363
4.49ProThr: 4.49 ± 1.353
4.49ProVal: 4.49 ± 0.487
0.0ProTrp: 0.0 ± 0.0
2.566ProTyr: 2.566 ± 0.897
0.0ProXaa: 0.0 ± 0.0
Gln
3.207GlnAla: 3.207 ± 1.338
0.0GlnCys: 0.0 ± 0.0
0.641GlnAsp: 0.641 ± 0.425
1.283GlnGlu: 1.283 ± 0.881
1.283GlnPhe: 1.283 ± 0.016
3.207GlnGly: 3.207 ± 0.394
0.0GlnHis: 0.0 ± 0.0
1.283GlnIle: 1.283 ± 0.85
0.641GlnLys: 0.641 ± 0.441
0.641GlnLeu: 0.641 ± 0.425
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.849GlnPro: 3.849 ± 1.779
1.924GlnGln: 1.924 ± 0.41
0.0GlnArg: 0.0 ± 0.0
2.566GlnSer: 2.566 ± 0.031
0.641GlnThr: 0.641 ± 0.441
2.566GlnVal: 2.566 ± 0.031
0.641GlnTrp: 0.641 ± 0.441
1.283GlnTyr: 1.283 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
7.056ArgAla: 7.056 ± 1.213
3.207ArgCys: 3.207 ± 2.126
5.773ArgAsp: 5.773 ± 2.961
1.924ArgGlu: 1.924 ± 1.322
0.641ArgPhe: 0.641 ± 0.441
8.98ArgGly: 8.98 ± 1.841
4.49ArgHis: 4.49 ± 0.487
3.849ArgIle: 3.849 ± 1.685
0.641ArgLys: 0.641 ± 0.441
4.49ArgLeu: 4.49 ± 0.487
0.641ArgMet: 0.641 ± 0.425
1.283ArgAsn: 1.283 ± 0.881
2.566ArgPro: 2.566 ± 0.835
1.283ArgGln: 1.283 ± 0.016
7.056ArgArg: 7.056 ± 1.213
7.056ArgSer: 7.056 ± 1.213
4.49ArgThr: 4.49 ± 0.487
5.773ArgVal: 5.773 ± 0.503
2.566ArgTrp: 2.566 ± 0.835
1.283ArgTyr: 1.283 ± 0.881
0.0ArgXaa: 0.0 ± 0.0
Ser
6.414SerAla: 6.414 ± 0.788
1.283SerCys: 1.283 ± 0.016
4.49SerAsp: 4.49 ± 1.244
0.641SerGlu: 0.641 ± 0.425
3.207SerPhe: 3.207 ± 2.126
10.263SerGly: 10.263 ± 1.856
1.924SerHis: 1.924 ± 1.276
3.207SerIle: 3.207 ± 0.394
1.924SerLys: 1.924 ± 1.276
5.131SerLeu: 5.131 ± 0.928
3.849SerMet: 3.849 ± 1.685
3.207SerAsn: 3.207 ± 1.338
5.773SerPro: 5.773 ± 1.369
0.0SerGln: 0.0 ± 0.0
3.207SerArg: 3.207 ± 0.394
7.056SerSer: 7.056 ± 2.945
1.924SerThr: 1.924 ± 0.456
9.622SerVal: 9.622 ± 2.281
1.924SerTrp: 1.924 ± 0.41
2.566SerTyr: 2.566 ± 0.031
0.0SerXaa: 0.0 ± 0.0
Thr
3.849ThrAla: 3.849 ± 0.047
1.283ThrCys: 1.283 ± 0.016
5.131ThrAsp: 5.131 ± 0.804
2.566ThrGlu: 2.566 ± 1.701
1.283ThrPhe: 1.283 ± 0.016
4.49ThrGly: 4.49 ± 0.487
0.641ThrHis: 0.641 ± 0.425
1.924ThrIle: 1.924 ± 1.322
0.641ThrLys: 0.641 ± 0.441
6.414ThrLeu: 6.414 ± 0.788
1.924ThrMet: 1.924 ± 0.41
0.641ThrAsn: 0.641 ± 0.441
2.566ThrPro: 2.566 ± 0.897
0.641ThrGln: 0.641 ± 0.441
3.207ThrArg: 3.207 ± 1.26
4.49ThrSer: 4.49 ± 1.353
7.697ThrThr: 7.697 ± 0.773
6.414ThrVal: 6.414 ± 1.81
0.0ThrTrp: 0.0 ± 0.0
2.566ThrTyr: 2.566 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
7.056ValAla: 7.056 ± 3.116
0.0ValCys: 0.0 ± 0.0
2.566ValAsp: 2.566 ± 0.031
5.131ValGlu: 5.131 ± 0.928
4.49ValPhe: 4.49 ± 2.219
7.697ValGly: 7.697 ± 0.093
1.283ValHis: 1.283 ± 0.016
0.641ValIle: 0.641 ± 0.441
1.924ValLys: 1.924 ± 1.276
7.056ValLeu: 7.056 ± 0.519
2.566ValMet: 2.566 ± 1.508
3.207ValAsn: 3.207 ± 0.394
7.697ValPro: 7.697 ± 0.093
1.283ValGln: 1.283 ± 0.016
5.773ValArg: 5.773 ± 0.363
7.697ValSer: 7.697 ± 0.773
4.49ValThr: 4.49 ± 1.353
3.207ValVal: 3.207 ± 0.472
0.0ValTrp: 0.0 ± 0.0
3.207ValTyr: 3.207 ± 0.472
0.0ValXaa: 0.0 ± 0.0
Trp
1.924TrpAla: 1.924 ± 0.41
1.283TrpCys: 1.283 ± 0.016
0.641TrpAsp: 0.641 ± 0.441
1.924TrpGlu: 1.924 ± 0.456
0.0TrpPhe: 0.0 ± 0.0
0.641TrpGly: 0.641 ± 0.425
0.0TrpHis: 0.0 ± 0.0
1.283TrpIle: 1.283 ± 0.881
0.641TrpLys: 0.641 ± 0.425
0.641TrpLeu: 0.641 ± 0.425
0.0TrpMet: 0.0 ± 0.0
0.641TrpAsn: 0.641 ± 0.425
0.0TrpPro: 0.0 ± 0.0
0.641TrpGln: 0.641 ± 0.425
1.283TrpArg: 1.283 ± 0.881
1.283TrpSer: 1.283 ± 0.85
0.0TrpThr: 0.0 ± 0.0
0.641TrpVal: 0.641 ± 0.425
0.0TrpTrp: 0.0 ± 0.0
0.641TrpTyr: 0.641 ± 0.425
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.773TyrAla: 5.773 ± 0.363
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
1.283TyrGlu: 1.283 ± 0.016
0.641TyrPhe: 0.641 ± 0.441
1.924TyrGly: 1.924 ± 0.456
1.283TyrHis: 1.283 ± 0.85
0.641TyrIle: 0.641 ± 0.425
1.283TyrLys: 1.283 ± 0.016
6.414TyrLeu: 6.414 ± 2.52
0.641TyrMet: 0.641 ± 0.441
0.0TyrAsn: 0.0 ± 0.0
3.207TyrPro: 3.207 ± 0.472
0.641TyrGln: 0.641 ± 0.441
1.924TyrArg: 1.924 ± 0.456
3.849TyrSer: 3.849 ± 0.047
0.641TyrThr: 0.641 ± 0.425
1.283TyrVal: 1.283 ± 0.85
0.0TyrTrp: 0.0 ± 0.0
0.641TyrTyr: 0.641 ± 0.425
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1560 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski