Amino acid dipepetide frequency for Tortoise microvirus 72

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.995AlaAla: 10.995 ± 5.019
0.0AlaCys: 0.0 ± 0.0
4.051AlaAsp: 4.051 ± 1.227
5.208AlaGlu: 5.208 ± 1.338
2.315AlaPhe: 2.315 ± 1.331
7.523AlaGly: 7.523 ± 4.317
2.894AlaHis: 2.894 ± 1.515
4.63AlaIle: 4.63 ± 1.503
5.787AlaLys: 5.787 ± 2.732
6.366AlaLeu: 6.366 ± 1.314
1.736AlaMet: 1.736 ± 0.81
5.787AlaAsn: 5.787 ± 2.02
3.472AlaPro: 3.472 ± 1.652
3.472AlaGln: 3.472 ± 0.506
7.523AlaArg: 7.523 ± 3.76
4.63AlaSer: 4.63 ± 1.385
8.102AlaThr: 8.102 ± 3.272
9.838AlaVal: 9.838 ± 1.463
2.315AlaTrp: 2.315 ± 1.37
1.736AlaTyr: 1.736 ± 1.352
0.0AlaXaa: 0.0 ± 0.0
Cys
1.157CysAla: 1.157 ± 0.831
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.157CysIle: 1.157 ± 1.067
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.579CysGln: 0.579 ± 0.534
0.579CysArg: 0.579 ± 0.534
0.579CysSer: 0.579 ± 0.451
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.579CysTrp: 0.579 ± 0.534
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.787AspAla: 5.787 ± 1.266
0.0AspCys: 0.0 ± 0.0
3.472AspAsp: 3.472 ± 1.481
2.894AspGlu: 2.894 ± 1.048
1.157AspPhe: 1.157 ± 0.901
6.366AspGly: 6.366 ± 2.391
1.157AspHis: 1.157 ± 1.067
5.208AspIle: 5.208 ± 1.462
1.157AspLys: 1.157 ± 0.831
4.051AspLeu: 4.051 ± 1.568
0.579AspMet: 0.579 ± 0.451
1.736AspAsn: 1.736 ± 1.284
4.63AspPro: 4.63 ± 0.94
1.736AspGln: 1.736 ± 0.81
2.315AspArg: 2.315 ± 1.328
1.736AspSer: 1.736 ± 0.553
1.157AspThr: 1.157 ± 0.723
4.63AspVal: 4.63 ± 2.141
1.157AspTrp: 1.157 ± 0.831
0.579AspTyr: 0.579 ± 0.534
0.0AspXaa: 0.0 ± 0.0
Glu
6.366GluAla: 6.366 ± 2.755
0.0GluCys: 0.0 ± 0.0
0.579GluAsp: 0.579 ± 0.618
2.894GluGlu: 2.894 ± 1.829
2.315GluPhe: 2.315 ± 0.816
4.051GluGly: 4.051 ± 1.267
1.157GluHis: 1.157 ± 0.517
4.051GluIle: 4.051 ± 0.893
4.63GluLys: 4.63 ± 3.288
4.63GluLeu: 4.63 ± 1.922
2.315GluMet: 2.315 ± 1.436
0.579GluAsn: 0.579 ± 0.675
4.051GluPro: 4.051 ± 1.47
4.63GluGln: 4.63 ± 1.571
8.102GluArg: 8.102 ± 3.022
1.157GluSer: 1.157 ± 0.662
4.63GluThr: 4.63 ± 1.568
5.208GluVal: 5.208 ± 2.05
2.894GluTrp: 2.894 ± 1.47
3.472GluTyr: 3.472 ± 1.823
0.0GluXaa: 0.0 ± 0.0
Phe
1.736PheAla: 1.736 ± 0.769
0.0PheCys: 0.0 ± 0.0
1.736PheAsp: 1.736 ± 0.95
3.472PheGlu: 3.472 ± 1.481
1.157PhePhe: 1.157 ± 0.738
3.472PheGly: 3.472 ± 1.215
0.579PheHis: 0.579 ± 0.618
1.157PheIle: 1.157 ± 0.517
1.157PheLys: 1.157 ± 0.517
1.157PheLeu: 1.157 ± 1.067
0.579PheMet: 0.579 ± 0.708
2.315PheAsn: 2.315 ± 1.45
2.315PhePro: 2.315 ± 1.663
2.894PheGln: 2.894 ± 1.683
1.157PheArg: 1.157 ± 0.797
1.157PheSer: 1.157 ± 0.809
2.894PheThr: 2.894 ± 0.557
3.472PheVal: 3.472 ± 1.336
0.0PheTrp: 0.0 ± 0.0
1.736PheTyr: 1.736 ± 0.81
0.0PheXaa: 0.0 ± 0.0
Gly
6.944GlyAla: 6.944 ± 2.214
0.579GlyCys: 0.579 ± 0.708
5.208GlyAsp: 5.208 ± 0.851
5.787GlyGlu: 5.787 ± 1.89
4.051GlyPhe: 4.051 ± 1.877
12.153GlyGly: 12.153 ± 5.637
1.736GlyHis: 1.736 ± 1.199
4.051GlyIle: 4.051 ± 1.139
2.315GlyLys: 2.315 ± 0.816
3.472GlyLeu: 3.472 ± 1.734
0.579GlyMet: 0.579 ± 0.497
4.63GlyAsn: 4.63 ± 3.456
2.894GlyPro: 2.894 ± 1.524
4.051GlyGln: 4.051 ± 1.478
8.681GlyArg: 8.681 ± 2.691
4.63GlySer: 4.63 ± 2.484
6.944GlyThr: 6.944 ± 4.1
9.259GlyVal: 9.259 ± 3.353
1.736GlyTrp: 1.736 ± 1.558
1.157GlyTyr: 1.157 ± 0.517
0.0GlyXaa: 0.0 ± 0.0
His
2.315HisAla: 2.315 ± 1.36
0.0HisCys: 0.0 ± 0.0
1.736HisAsp: 1.736 ± 0.805
2.315HisGlu: 2.315 ± 0.856
0.579HisPhe: 0.579 ± 0.534
1.157HisGly: 1.157 ± 1.067
0.0HisHis: 0.0 ± 0.0
1.736HisIle: 1.736 ± 1.601
0.579HisLys: 0.579 ± 0.708
1.736HisLeu: 1.736 ± 1.204
0.0HisMet: 0.0 ± 0.0
1.157HisAsn: 1.157 ± 0.662
1.157HisPro: 1.157 ± 1.416
0.0HisGln: 0.0 ± 0.0
1.736HisArg: 1.736 ± 0.769
0.579HisSer: 0.579 ± 0.708
0.0HisThr: 0.0 ± 0.0
0.579HisVal: 0.579 ± 0.534
2.315HisTrp: 2.315 ± 1.169
1.157HisTyr: 1.157 ± 0.685
0.0HisXaa: 0.0 ± 0.0
Ile
2.894IleAla: 2.894 ± 1.465
0.0IleCys: 0.0 ± 0.0
1.736IleAsp: 1.736 ± 0.997
3.472IleGlu: 3.472 ± 1.995
1.157IlePhe: 1.157 ± 1.351
4.63IleGly: 4.63 ± 0.94
1.157IleHis: 1.157 ± 0.797
1.157IleIle: 1.157 ± 0.738
2.315IleLys: 2.315 ± 1.005
1.157IleLeu: 1.157 ± 0.738
1.157IleMet: 1.157 ± 1.416
1.157IleAsn: 1.157 ± 0.738
5.208IlePro: 5.208 ± 1.316
2.315IleGln: 2.315 ± 2.134
2.315IleArg: 2.315 ± 1.323
2.894IleSer: 2.894 ± 1.412
1.736IleThr: 1.736 ± 0.717
4.051IleVal: 4.051 ± 1.204
0.0IleTrp: 0.0 ± 0.0
2.894IleTyr: 2.894 ± 1.432
0.0IleXaa: 0.0 ± 0.0
Lys
3.472LysAla: 3.472 ± 1.336
0.0LysCys: 0.0 ± 0.0
2.315LysAsp: 2.315 ± 1.026
4.051LysGlu: 4.051 ± 2.299
1.736LysPhe: 1.736 ± 1.601
1.736LysGly: 1.736 ± 1.601
0.579LysHis: 0.579 ± 0.534
1.736LysIle: 1.736 ± 0.997
2.315LysLys: 2.315 ± 1.525
5.208LysLeu: 5.208 ± 1.869
0.579LysMet: 0.579 ± 0.451
2.894LysAsn: 2.894 ± 1.354
6.366LysPro: 6.366 ± 4.532
2.894LysGln: 2.894 ± 1.361
5.208LysArg: 5.208 ± 3.386
1.157LysSer: 1.157 ± 0.517
1.157LysThr: 1.157 ± 0.901
2.315LysVal: 2.315 ± 1.328
0.579LysTrp: 0.579 ± 0.534
0.579LysTyr: 0.579 ± 0.534
0.0LysXaa: 0.0 ± 0.0
Leu
7.523LeuAla: 7.523 ± 2.348
0.0LeuCys: 0.0 ± 0.0
2.315LeuAsp: 2.315 ± 0.861
2.315LeuGlu: 2.315 ± 1.005
2.315LeuPhe: 2.315 ± 1.328
6.366LeuGly: 6.366 ± 1.293
1.736LeuHis: 1.736 ± 0.989
1.157LeuIle: 1.157 ± 0.738
5.208LeuLys: 5.208 ± 2.573
4.051LeuLeu: 4.051 ± 2.059
2.894LeuMet: 2.894 ± 2.371
2.315LeuAsn: 2.315 ± 1.645
4.051LeuPro: 4.051 ± 1.461
3.472LeuGln: 3.472 ± 1.241
4.051LeuArg: 4.051 ± 1.441
4.63LeuSer: 4.63 ± 0.993
4.051LeuThr: 4.051 ± 1.424
3.472LeuVal: 3.472 ± 2.626
1.157LeuTrp: 1.157 ± 0.831
4.63LeuTyr: 4.63 ± 2.801
0.0LeuXaa: 0.0 ± 0.0
Met
2.894MetAla: 2.894 ± 1.738
0.579MetCys: 0.579 ± 0.534
1.157MetAsp: 1.157 ± 0.797
1.157MetGlu: 1.157 ± 1.501
0.0MetPhe: 0.0 ± 0.0
1.736MetGly: 1.736 ± 1.413
0.579MetHis: 0.579 ± 0.451
1.736MetIle: 1.736 ± 0.997
0.0MetLys: 0.0 ± 0.0
0.579MetLeu: 0.579 ± 0.451
0.0MetMet: 0.0 ± 0.0
0.579MetAsn: 0.579 ± 0.451
1.736MetPro: 1.736 ± 0.997
0.579MetGln: 0.579 ± 0.534
0.579MetArg: 0.579 ± 0.451
2.315MetSer: 2.315 ± 1.328
1.157MetThr: 1.157 ± 0.738
0.579MetVal: 0.579 ± 0.451
0.579MetTrp: 0.579 ± 0.451
0.579MetTyr: 0.579 ± 0.534
0.0MetXaa: 0.0 ± 0.0
Asn
2.315AsnAla: 2.315 ± 1.789
0.579AsnCys: 0.579 ± 0.534
0.579AsnAsp: 0.579 ± 0.451
2.894AsnGlu: 2.894 ± 1.16
0.579AsnPhe: 0.579 ± 0.451
4.63AsnGly: 4.63 ± 1.242
0.579AsnHis: 0.579 ± 0.451
1.157AsnIle: 1.157 ± 0.819
3.472AsnLys: 3.472 ± 1.215
1.736AsnLeu: 1.736 ± 0.717
1.157AsnMet: 1.157 ± 0.569
0.0AsnAsn: 0.0 ± 0.0
5.208AsnPro: 5.208 ± 2.16
1.157AsnGln: 1.157 ± 0.662
1.736AsnArg: 1.736 ± 1.408
1.736AsnSer: 1.736 ± 1.352
1.736AsnThr: 1.736 ± 0.553
4.63AsnVal: 4.63 ± 1.17
1.157AsnTrp: 1.157 ± 0.517
1.157AsnTyr: 1.157 ± 0.723
0.0AsnXaa: 0.0 ± 0.0
Pro
6.366ProAla: 6.366 ± 1.452
0.579ProCys: 0.579 ± 0.534
4.63ProAsp: 4.63 ± 1.11
5.208ProGlu: 5.208 ± 2.379
2.315ProPhe: 2.315 ± 1.36
4.051ProGly: 4.051 ± 1.203
1.157ProHis: 1.157 ± 1.416
2.894ProIle: 2.894 ± 1.03
3.472ProLys: 3.472 ± 1.241
2.315ProLeu: 2.315 ± 0.862
1.736ProMet: 1.736 ± 0.95
1.736ProAsn: 1.736 ± 0.998
3.472ProPro: 3.472 ± 1.61
1.157ProGln: 1.157 ± 0.662
3.472ProArg: 3.472 ± 0.728
2.315ProSer: 2.315 ± 1.404
2.894ProThr: 2.894 ± 1.257
6.944ProVal: 6.944 ± 1.667
0.579ProTrp: 0.579 ± 0.451
2.894ProTyr: 2.894 ± 0.639
0.0ProXaa: 0.0 ± 0.0
Gln
4.63GlnAla: 4.63 ± 1.39
0.579GlnCys: 0.579 ± 0.534
2.315GlnAsp: 2.315 ± 0.877
1.736GlnGlu: 1.736 ± 1.601
2.894GlnPhe: 2.894 ± 1.452
1.736GlnGly: 1.736 ± 1.862
1.736GlnHis: 1.736 ± 0.553
0.0GlnIle: 0.0 ± 0.0
1.157GlnLys: 1.157 ± 1.067
5.787GlnLeu: 5.787 ± 1.741
1.157GlnMet: 1.157 ± 0.515
2.315GlnAsn: 2.315 ± 1.005
1.157GlnPro: 1.157 ± 0.517
2.315GlnGln: 2.315 ± 0.816
5.208GlnArg: 5.208 ± 1.145
2.894GlnSer: 2.894 ± 1.482
1.736GlnThr: 1.736 ± 1.061
0.579GlnVal: 0.579 ± 0.451
2.894GlnTrp: 2.894 ± 1.495
1.736GlnTyr: 1.736 ± 0.553
0.0GlnXaa: 0.0 ± 0.0
Arg
6.366ArgAla: 6.366 ± 2.459
0.0ArgCys: 0.0 ± 0.0
5.787ArgAsp: 5.787 ± 1.709
5.787ArgGlu: 5.787 ± 1.968
1.736ArgPhe: 1.736 ± 0.95
4.051ArgGly: 4.051 ± 1.713
0.579ArgHis: 0.579 ± 0.618
2.894ArgIle: 2.894 ± 1.652
4.051ArgLys: 4.051 ± 1.719
6.366ArgLeu: 6.366 ± 2.145
2.894ArgMet: 2.894 ± 1.285
3.472ArgAsn: 3.472 ± 1.245
1.736ArgPro: 1.736 ± 0.717
8.102ArgGln: 8.102 ± 2.425
4.051ArgArg: 4.051 ± 1.139
3.472ArgSer: 3.472 ± 1.383
4.051ArgThr: 4.051 ± 2.469
2.894ArgVal: 2.894 ± 1.094
1.157ArgTrp: 1.157 ± 0.685
4.63ArgTyr: 4.63 ± 1.598
0.0ArgXaa: 0.0 ± 0.0
Ser
4.051SerAla: 4.051 ± 1.564
1.157SerCys: 1.157 ± 0.517
2.894SerAsp: 2.894 ± 0.948
3.472SerGlu: 3.472 ± 0.728
1.736SerPhe: 1.736 ± 1.199
6.944SerGly: 6.944 ± 3.19
0.579SerHis: 0.579 ± 0.534
2.894SerIle: 2.894 ± 1.91
3.472SerLys: 3.472 ± 2.01
4.63SerLeu: 4.63 ± 2.614
0.0SerMet: 0.0 ± 0.0
1.736SerAsn: 1.736 ± 1.19
2.315SerPro: 2.315 ± 1.052
0.579SerGln: 0.579 ± 0.534
2.315SerArg: 2.315 ± 1.47
1.157SerSer: 1.157 ± 1.493
1.736SerThr: 1.736 ± 1.352
3.472SerVal: 3.472 ± 0.506
1.157SerTrp: 1.157 ± 1.493
1.736SerTyr: 1.736 ± 1.177
0.0SerXaa: 0.0 ± 0.0
Thr
6.366ThrAla: 6.366 ± 1.949
0.0ThrCys: 0.0 ± 0.0
1.736ThrAsp: 1.736 ± 0.95
3.472ThrGlu: 3.472 ± 1.501
1.736ThrPhe: 1.736 ± 0.694
5.208ThrGly: 5.208 ± 2.28
0.579ThrHis: 0.579 ± 0.451
1.736ThrIle: 1.736 ± 0.694
1.736ThrLys: 1.736 ± 0.553
4.63ThrLeu: 4.63 ± 1.397
0.0ThrMet: 0.0 ± 0.0
2.315ThrAsn: 2.315 ± 0.926
4.051ThrPro: 4.051 ± 1.786
1.157ThrGln: 1.157 ± 1.333
4.051ThrArg: 4.051 ± 2.827
0.579ThrSer: 0.579 ± 0.618
3.472ThrThr: 3.472 ± 1.501
4.63ThrVal: 4.63 ± 2.123
0.579ThrTrp: 0.579 ± 0.708
4.63ThrTyr: 4.63 ± 1.76
0.0ThrXaa: 0.0 ± 0.0
Val
8.102ValAla: 8.102 ± 1.655
0.0ValCys: 0.0 ± 0.0
4.051ValAsp: 4.051 ± 1.265
5.208ValGlu: 5.208 ± 2.293
2.315ValPhe: 2.315 ± 0.802
8.681ValGly: 8.681 ± 2.096
2.894ValHis: 2.894 ± 2.004
2.315ValIle: 2.315 ± 1.446
1.736ValLys: 1.736 ± 1.352
4.051ValLeu: 4.051 ± 1.315
0.579ValMet: 0.579 ± 0.614
2.894ValAsn: 2.894 ± 2.253
2.894ValPro: 2.894 ± 1.746
1.157ValGln: 1.157 ± 1.067
6.944ValArg: 6.944 ± 1.38
5.208ValSer: 5.208 ± 1.874
4.051ValThr: 4.051 ± 0.928
6.366ValVal: 6.366 ± 2.125
2.315ValTrp: 2.315 ± 1.494
2.315ValTyr: 2.315 ± 0.802
0.0ValXaa: 0.0 ± 0.0
Trp
1.736TrpAla: 1.736 ± 0.95
0.0TrpCys: 0.0 ± 0.0
1.736TrpAsp: 1.736 ± 0.989
1.736TrpGlu: 1.736 ± 1.204
1.736TrpPhe: 1.736 ± 0.998
1.736TrpGly: 1.736 ± 0.717
0.579TrpHis: 0.579 ± 0.534
1.157TrpIle: 1.157 ± 1.29
0.0TrpLys: 0.0 ± 0.0
1.157TrpLeu: 1.157 ± 1.333
0.0TrpMet: 0.0 ± 0.0
0.579TrpAsn: 0.579 ± 0.708
1.736TrpPro: 1.736 ± 1.9
2.315TrpGln: 2.315 ± 0.57
1.736TrpArg: 1.736 ± 1.449
2.315TrpSer: 2.315 ± 1.37
0.579TrpThr: 0.579 ± 0.534
1.157TrpVal: 1.157 ± 1.235
0.0TrpTrp: 0.0 ± 0.0
1.157TrpTyr: 1.157 ± 0.685
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.366TyrAla: 6.366 ± 1.896
0.579TyrCys: 0.579 ± 0.534
3.472TyrAsp: 3.472 ± 0.947
4.63TyrGlu: 4.63 ± 0.926
2.315TyrPhe: 2.315 ± 1.534
4.63TyrGly: 4.63 ± 2.485
0.579TyrHis: 0.579 ± 0.534
0.579TyrIle: 0.579 ± 0.534
2.315TyrLys: 2.315 ± 1.476
4.63TyrLeu: 4.63 ± 2.508
0.579TyrMet: 0.579 ± 0.675
0.579TyrAsn: 0.579 ± 0.451
1.736TyrPro: 1.736 ± 0.949
0.0TyrGln: 0.0 ± 0.0
2.315TyrArg: 2.315 ± 0.958
2.894TyrSer: 2.894 ± 1.635
0.579TyrThr: 0.579 ± 0.675
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
1.157TyrTyr: 1.157 ± 0.517
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski