Amino acid dipepetide frequency for Falconid herpesvirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.189AlaAla: 13.189 ± 1.062
1.839AlaCys: 1.839 ± 0.208
5.581AlaAsp: 5.581 ± 0.443
5.602AlaGlu: 5.602 ± 0.496
3.658AlaPhe: 3.658 ± 0.323
7.483AlaGly: 7.483 ± 0.514
1.275AlaHis: 1.275 ± 0.189
3.846AlaIle: 3.846 ± 0.318
3.261AlaLys: 3.261 ± 0.308
8.925AlaLeu: 8.925 ± 0.634
2.132AlaMet: 2.132 ± 0.18
2.738AlaAsn: 2.738 ± 0.241
5.351AlaPro: 5.351 ± 0.407
2.111AlaGln: 2.111 ± 0.196
8.382AlaArg: 8.382 ± 0.549
7.943AlaSer: 7.943 ± 0.563
5.706AlaThr: 5.706 ± 0.353
7.796AlaVal: 7.796 ± 0.46
0.982AlaTrp: 0.982 ± 0.176
2.822AlaTyr: 2.822 ± 0.256
0.021AlaXaa: 0.021 ± 0.019
Cys
1.777CysAla: 1.777 ± 0.259
0.669CysCys: 0.669 ± 0.131
1.505CysAsp: 1.505 ± 0.172
1.003CysGlu: 1.003 ± 0.151
0.648CysPhe: 0.648 ± 0.125
1.4CysGly: 1.4 ± 0.213
0.355CysHis: 0.355 ± 0.078
0.982CysIle: 0.982 ± 0.157
0.585CysLys: 0.585 ± 0.109
2.132CysLeu: 2.132 ± 0.194
0.585CysMet: 0.585 ± 0.131
0.711CysAsn: 0.711 ± 0.142
1.003CysPro: 1.003 ± 0.15
0.355CysGln: 0.355 ± 0.075
1.672CysArg: 1.672 ± 0.234
1.547CysSer: 1.547 ± 0.192
1.191CysThr: 1.191 ± 0.187
1.672CysVal: 1.672 ± 0.226
0.23CysTrp: 0.23 ± 0.082
0.585CysTyr: 0.585 ± 0.092
0.0CysXaa: 0.0 ± 0.0
Asp
7.817AspAla: 7.817 ± 0.449
0.752AspCys: 0.752 ± 0.127
5.769AspAsp: 5.769 ± 0.605
4.18AspGlu: 4.18 ± 0.399
1.693AspPhe: 1.693 ± 0.151
5.497AspGly: 5.497 ± 0.367
0.899AspHis: 0.899 ± 0.16
2.048AspIle: 2.048 ± 0.211
1.505AspLys: 1.505 ± 0.172
4.682AspLeu: 4.682 ± 0.356
1.547AspMet: 1.547 ± 0.171
1.505AspAsn: 1.505 ± 0.208
3.47AspPro: 3.47 ± 0.275
1.296AspGln: 1.296 ± 0.152
4.745AspArg: 4.745 ± 0.366
4.766AspSer: 4.766 ± 0.365
2.487AspThr: 2.487 ± 0.23
4.912AspVal: 4.912 ± 0.339
0.815AspTrp: 0.815 ± 0.13
1.965AspTyr: 1.965 ± 0.166
0.0AspXaa: 0.0 ± 0.0
Glu
4.828GluAla: 4.828 ± 0.386
1.212GluCys: 1.212 ± 0.181
4.076GluAsp: 4.076 ± 0.342
4.661GluGlu: 4.661 ± 0.403
1.38GluPhe: 1.38 ± 0.208
3.825GluGly: 3.825 ± 0.295
1.003GluHis: 1.003 ± 0.154
2.132GluIle: 2.132 ± 0.211
1.735GluLys: 1.735 ± 0.211
4.766GluLeu: 4.766 ± 0.363
1.359GluMet: 1.359 ± 0.151
1.798GluAsn: 1.798 ± 0.205
2.947GluPro: 2.947 ± 0.282
1.191GluGln: 1.191 ± 0.149
4.954GluArg: 4.954 ± 0.359
3.741GluSer: 3.741 ± 0.252
3.344GluThr: 3.344 ± 0.288
3.073GluVal: 3.073 ± 0.22
0.627GluTrp: 0.627 ± 0.124
1.798GluTyr: 1.798 ± 0.174
0.0GluXaa: 0.0 ± 0.0
Phe
3.031PheAla: 3.031 ± 0.295
0.773PheCys: 0.773 ± 0.128
2.341PheAsp: 2.341 ± 0.205
1.484PheGlu: 1.484 ± 0.172
1.609PhePhe: 1.609 ± 0.224
2.383PheGly: 2.383 ± 0.22
0.69PheHis: 0.69 ± 0.125
1.798PheIle: 1.798 ± 0.208
1.129PheLys: 1.129 ± 0.172
3.052PheLeu: 3.052 ± 0.354
0.836PheMet: 0.836 ± 0.147
1.066PheAsn: 1.066 ± 0.148
2.069PhePro: 2.069 ± 0.232
0.669PheGln: 0.669 ± 0.107
1.944PheArg: 1.944 ± 0.203
3.114PheSer: 3.114 ± 0.291
1.693PheThr: 1.693 ± 0.18
2.487PheVal: 2.487 ± 0.235
0.606PheTrp: 0.606 ± 0.136
1.38PheTyr: 1.38 ± 0.163
0.0PheXaa: 0.0 ± 0.0
Gly
7.169GlyAla: 7.169 ± 0.501
1.505GlyCys: 1.505 ± 0.212
4.598GlyAsp: 4.598 ± 0.376
5.037GlyGlu: 5.037 ± 0.323
2.216GlyPhe: 2.216 ± 0.316
9.97GlyGly: 9.97 ± 1.071
1.296GlyHis: 1.296 ± 0.164
1.923GlyIle: 1.923 ± 0.179
2.655GlyLys: 2.655 ± 0.246
5.978GlyLeu: 5.978 ± 0.325
1.756GlyMet: 1.756 ± 0.197
1.777GlyAsn: 1.777 ± 0.233
4.452GlyPro: 4.452 ± 0.398
2.069GlyGln: 2.069 ± 0.224
7.587GlyArg: 7.587 ± 0.653
6.333GlySer: 6.333 ± 0.432
3.992GlyThr: 3.992 ± 0.281
4.327GlyVal: 4.327 ± 0.401
1.003GlyTrp: 1.003 ± 0.18
1.609GlyTyr: 1.609 ± 0.191
0.0GlyXaa: 0.0 ± 0.0
His
1.756HisAla: 1.756 ± 0.167
0.481HisCys: 0.481 ± 0.149
0.773HisAsp: 0.773 ± 0.107
0.732HisGlu: 0.732 ± 0.119
0.752HisPhe: 0.752 ± 0.137
1.651HisGly: 1.651 ± 0.182
0.523HisHis: 0.523 ± 0.108
0.69HisIle: 0.69 ± 0.119
0.606HisLys: 0.606 ± 0.122
1.902HisLeu: 1.902 ± 0.218
0.314HisMet: 0.314 ± 0.087
0.732HisAsn: 0.732 ± 0.164
1.63HisPro: 1.63 ± 0.195
0.334HisGln: 0.334 ± 0.083
1.881HisArg: 1.881 ± 0.25
1.338HisSer: 1.338 ± 0.216
1.066HisThr: 1.066 ± 0.14
1.359HisVal: 1.359 ± 0.145
0.105HisTrp: 0.105 ± 0.05
0.439HisTyr: 0.439 ± 0.11
0.0HisXaa: 0.0 ± 0.0
Ile
3.595IleAla: 3.595 ± 0.285
0.899IleCys: 0.899 ± 0.157
2.362IleAsp: 2.362 ± 0.216
2.048IleGlu: 2.048 ± 0.226
1.693IlePhe: 1.693 ± 0.204
2.32IleGly: 2.32 ± 0.245
0.773IleHis: 0.773 ± 0.132
1.902IleIle: 1.902 ± 0.203
1.923IleLys: 1.923 ± 0.256
3.261IleLeu: 3.261 ± 0.28
1.15IleMet: 1.15 ± 0.169
1.442IleAsn: 1.442 ± 0.191
2.508IlePro: 2.508 ± 0.238
1.233IleGln: 1.233 ± 0.15
2.717IleArg: 2.717 ± 0.221
2.905IleSer: 2.905 ± 0.254
2.404IleThr: 2.404 ± 0.235
2.571IleVal: 2.571 ± 0.321
0.397IleTrp: 0.397 ± 0.093
1.254IleTyr: 1.254 ± 0.189
0.0IleXaa: 0.0 ± 0.0
Lys
2.801LysAla: 2.801 ± 0.268
0.648LysCys: 0.648 ± 0.126
1.756LysAsp: 1.756 ± 0.18
1.839LysGlu: 1.839 ± 0.22
0.773LysPhe: 0.773 ± 0.134
2.257LysGly: 2.257 ± 0.23
0.941LysHis: 0.941 ± 0.17
1.568LysIle: 1.568 ± 0.195
1.63LysLys: 1.63 ± 0.257
2.571LysLeu: 2.571 ± 0.327
0.794LysMet: 0.794 ± 0.107
1.129LysAsn: 1.129 ± 0.147
1.86LysPro: 1.86 ± 0.231
0.961LysGln: 0.961 ± 0.146
3.511LysArg: 3.511 ± 0.331
2.174LysSer: 2.174 ± 0.274
2.655LysThr: 2.655 ± 0.23
1.777LysVal: 1.777 ± 0.212
0.585LysTrp: 0.585 ± 0.106
1.108LysTyr: 1.108 ± 0.137
0.0LysXaa: 0.0 ± 0.0
Leu
7.984LeuAla: 7.984 ± 0.497
2.09LeuCys: 2.09 ± 0.24
4.786LeuAsp: 4.786 ± 0.38
4.577LeuGlu: 4.577 ± 0.348
3.679LeuPhe: 3.679 ± 0.312
5.727LeuGly: 5.727 ± 0.376
1.839LeuHis: 1.839 ± 0.204
3.532LeuIle: 3.532 ± 0.311
2.989LeuLys: 2.989 ± 0.265
8.298LeuLeu: 8.298 ± 0.518
1.86LeuMet: 1.86 ± 0.2
2.383LeuAsn: 2.383 ± 0.295
4.975LeuPro: 4.975 ± 0.323
2.299LeuGln: 2.299 ± 0.218
6.898LeuArg: 6.898 ± 0.378
6.918LeuSer: 6.918 ± 0.394
4.891LeuThr: 4.891 ± 0.371
5.497LeuVal: 5.497 ± 0.357
1.191LeuTrp: 1.191 ± 0.152
2.759LeuTyr: 2.759 ± 0.223
0.0LeuXaa: 0.0 ± 0.0
Met
2.864MetAla: 2.864 ± 0.229
0.376MetCys: 0.376 ± 0.09
1.547MetAsp: 1.547 ± 0.177
1.024MetGlu: 1.024 ± 0.173
1.045MetPhe: 1.045 ± 0.16
1.442MetGly: 1.442 ± 0.16
0.376MetHis: 0.376 ± 0.078
1.003MetIle: 1.003 ± 0.157
0.732MetLys: 0.732 ± 0.145
1.965MetLeu: 1.965 ± 0.198
0.439MetMet: 0.439 ± 0.098
0.711MetAsn: 0.711 ± 0.142
1.129MetPro: 1.129 ± 0.173
0.627MetGln: 0.627 ± 0.12
1.839MetArg: 1.839 ± 0.22
2.153MetSer: 2.153 ± 0.243
1.317MetThr: 1.317 ± 0.163
1.338MetVal: 1.338 ± 0.214
0.209MetTrp: 0.209 ± 0.067
0.711MetTyr: 0.711 ± 0.117
0.0MetXaa: 0.0 ± 0.0
Asn
2.675AsnAla: 2.675 ± 0.211
0.711AsnCys: 0.711 ± 0.128
1.902AsnAsp: 1.902 ± 0.212
1.233AsnGlu: 1.233 ± 0.188
1.087AsnPhe: 1.087 ± 0.155
1.986AsnGly: 1.986 ± 0.221
0.564AsnHis: 0.564 ± 0.102
1.484AsnIle: 1.484 ± 0.173
1.129AsnLys: 1.129 ± 0.166
2.32AsnLeu: 2.32 ± 0.222
0.815AsnMet: 0.815 ± 0.15
0.982AsnAsn: 0.982 ± 0.121
1.609AsnPro: 1.609 ± 0.221
0.543AsnGln: 0.543 ± 0.126
2.09AsnArg: 2.09 ± 0.219
2.236AsnSer: 2.236 ± 0.261
1.275AsnThr: 1.275 ± 0.167
2.195AsnVal: 2.195 ± 0.22
0.23AsnTrp: 0.23 ± 0.069
0.961AsnTyr: 0.961 ± 0.147
0.0AsnXaa: 0.0 ± 0.0
Pro
5.999ProAla: 5.999 ± 0.454
1.233ProCys: 1.233 ± 0.151
3.449ProAsp: 3.449 ± 0.27
3.407ProGlu: 3.407 ± 0.321
1.693ProPhe: 1.693 ± 0.193
4.306ProGly: 4.306 ± 0.352
1.296ProHis: 1.296 ± 0.188
1.986ProIle: 1.986 ± 0.232
2.007ProLys: 2.007 ± 0.215
4.577ProLeu: 4.577 ± 0.316
1.38ProMet: 1.38 ± 0.158
1.4ProAsn: 1.4 ± 0.145
6.563ProPro: 6.563 ± 0.607
2.257ProGln: 2.257 ± 0.307
5.309ProArg: 5.309 ± 0.423
6.187ProSer: 6.187 ± 0.468
3.428ProThr: 3.428 ± 0.288
3.47ProVal: 3.47 ± 0.259
0.606ProTrp: 0.606 ± 0.104
1.484ProTyr: 1.484 ± 0.187
0.0ProXaa: 0.0 ± 0.0
Gln
2.007GlnAla: 2.007 ± 0.218
0.543GlnCys: 0.543 ± 0.094
1.296GlnAsp: 1.296 ± 0.197
1.296GlnGlu: 1.296 ± 0.159
0.961GlnPhe: 0.961 ± 0.177
1.818GlnGly: 1.818 ± 0.196
0.502GlnHis: 0.502 ± 0.104
0.92GlnIle: 0.92 ± 0.139
1.003GlnLys: 1.003 ± 0.146
2.216GlnLeu: 2.216 ± 0.189
0.732GlnMet: 0.732 ± 0.141
0.794GlnAsn: 0.794 ± 0.105
1.547GlnPro: 1.547 ± 0.217
1.275GlnGln: 1.275 ± 0.24
2.445GlnArg: 2.445 ± 0.244
1.839GlnSer: 1.839 ± 0.26
2.257GlnThr: 2.257 ± 0.214
1.317GlnVal: 1.317 ± 0.126
0.251GlnTrp: 0.251 ± 0.076
0.711GlnTyr: 0.711 ± 0.117
0.0GlnXaa: 0.0 ± 0.0
Arg
7.629ArgAla: 7.629 ± 0.442
1.923ArgCys: 1.923 ± 0.273
4.996ArgAsp: 4.996 ± 0.324
4.243ArgGlu: 4.243 ± 0.298
2.843ArgPhe: 2.843 ± 0.261
7.002ArgGly: 7.002 ± 0.62
1.818ArgHis: 1.818 ± 0.23
3.219ArgIle: 3.219 ± 0.24
2.717ArgLys: 2.717 ± 0.291
6.96ArgLeu: 6.96 ± 0.469
1.693ArgMet: 1.693 ± 0.201
2.132ArgAsn: 2.132 ± 0.202
5.873ArgPro: 5.873 ± 0.395
2.466ArgGln: 2.466 ± 0.207
10.89ArgArg: 10.89 ± 0.928
7.044ArgSer: 7.044 ± 0.554
4.368ArgThr: 4.368 ± 0.326
5.455ArgVal: 5.455 ± 0.337
0.815ArgTrp: 0.815 ± 0.17
2.592ArgTyr: 2.592 ± 0.21
0.0ArgXaa: 0.0 ± 0.0
Ser
8.549SerAla: 8.549 ± 0.699
1.359SerCys: 1.359 ± 0.175
5.33SerAsp: 5.33 ± 0.391
3.93SerGlu: 3.93 ± 0.262
2.195SerPhe: 2.195 ± 0.244
6.814SerGly: 6.814 ± 0.384
1.672SerHis: 1.672 ± 0.243
2.905SerIle: 2.905 ± 0.238
2.153SerLys: 2.153 ± 0.222
6.856SerLeu: 6.856 ± 0.406
1.798SerMet: 1.798 ± 0.222
1.756SerAsn: 1.756 ± 0.223
4.912SerPro: 4.912 ± 0.388
1.986SerGln: 1.986 ± 0.237
7.086SerArg: 7.086 ± 0.467
9.51SerSer: 9.51 ± 1.094
5.121SerThr: 5.121 ± 0.327
5.518SerVal: 5.518 ± 0.272
0.794SerTrp: 0.794 ± 0.125
1.902SerTyr: 1.902 ± 0.211
0.0SerXaa: 0.0 ± 0.0
Thr
6.5ThrAla: 6.5 ± 0.467
0.899ThrCys: 0.899 ± 0.122
3.01ThrAsp: 3.01 ± 0.271
2.32ThrGlu: 2.32 ± 0.231
2.32ThrPhe: 2.32 ± 0.242
4.076ThrGly: 4.076 ± 0.29
1.4ThrHis: 1.4 ± 0.174
2.822ThrIle: 2.822 ± 0.283
1.714ThrLys: 1.714 ± 0.168
4.724ThrLeu: 4.724 ± 0.305
1.045ThrMet: 1.045 ± 0.125
1.568ThrAsn: 1.568 ± 0.194
4.18ThrPro: 4.18 ± 0.347
1.421ThrGln: 1.421 ± 0.174
4.201ThrArg: 4.201 ± 0.298
4.348ThrSer: 4.348 ± 0.317
4.577ThrThr: 4.577 ± 0.442
4.118ThrVal: 4.118 ± 0.316
0.752ThrTrp: 0.752 ± 0.122
1.881ThrTyr: 1.881 ± 0.233
0.0ThrXaa: 0.0 ± 0.0
Val
6.647ValAla: 6.647 ± 0.409
1.651ValCys: 1.651 ± 0.166
4.243ValAsp: 4.243 ± 0.32
3.574ValGlu: 3.574 ± 0.271
2.278ValPhe: 2.278 ± 0.244
4.515ValGly: 4.515 ± 0.355
1.066ValHis: 1.066 ± 0.144
2.905ValIle: 2.905 ± 0.291
2.132ValLys: 2.132 ± 0.215
6.563ValLeu: 6.563 ± 0.388
1.484ValMet: 1.484 ± 0.172
2.09ValAsn: 2.09 ± 0.222
4.243ValPro: 4.243 ± 0.33
1.756ValGln: 1.756 ± 0.189
5.142ValArg: 5.142 ± 0.353
5.121ValSer: 5.121 ± 0.35
3.637ValThr: 3.637 ± 0.334
5.372ValVal: 5.372 ± 0.382
0.732ValTrp: 0.732 ± 0.172
2.174ValTyr: 2.174 ± 0.254
0.0ValXaa: 0.0 ± 0.0
Trp
0.92TrpAla: 0.92 ± 0.153
0.251TrpCys: 0.251 ± 0.07
0.878TrpAsp: 0.878 ± 0.122
0.543TrpGlu: 0.543 ± 0.097
0.481TrpPhe: 0.481 ± 0.116
0.961TrpGly: 0.961 ± 0.168
0.209TrpHis: 0.209 ± 0.066
0.397TrpIle: 0.397 ± 0.078
0.606TrpLys: 0.606 ± 0.121
1.045TrpLeu: 1.045 ± 0.19
0.272TrpMet: 0.272 ± 0.08
0.293TrpAsn: 0.293 ± 0.072
0.606TrpPro: 0.606 ± 0.104
0.334TrpGln: 0.334 ± 0.087
1.296TrpArg: 1.296 ± 0.183
0.815TrpSer: 0.815 ± 0.148
0.711TrpThr: 0.711 ± 0.124
0.376TrpVal: 0.376 ± 0.072
0.293TrpTrp: 0.293 ± 0.105
0.334TrpTyr: 0.334 ± 0.078
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.905TyrAla: 2.905 ± 0.292
0.794TyrCys: 0.794 ± 0.141
2.153TyrAsp: 2.153 ± 0.181
1.714TyrGlu: 1.714 ± 0.157
1.15TyrPhe: 1.15 ± 0.188
1.818TyrGly: 1.818 ± 0.215
0.564TyrHis: 0.564 ± 0.113
1.296TyrIle: 1.296 ± 0.189
1.129TyrLys: 1.129 ± 0.156
2.383TyrLeu: 2.383 ± 0.214
0.836TyrMet: 0.836 ± 0.131
1.024TyrAsn: 1.024 ± 0.149
1.108TyrPro: 1.108 ± 0.143
0.543TyrGln: 0.543 ± 0.097
2.09TyrArg: 2.09 ± 0.198
2.09TyrSer: 2.09 ± 0.183
1.756TyrThr: 1.756 ± 0.205
2.696TyrVal: 2.696 ± 0.239
0.397TyrTrp: 0.397 ± 0.095
0.857TyrTyr: 0.857 ± 0.112
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.021XaaSer: 0.021 ± 0.019
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 108 proteins (47844 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski