Amino acid dipepetide frequency for Algoriella xinjiangensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.801AlaAla: 3.801 ± 0.078	0.495AlaCys: 0.495 ± 0.025	3.352AlaAsp: 3.352 ± 0.063	3.963AlaGlu: 3.963 ± 0.077	3.094AlaPhe: 3.094 ± 0.06	3.739AlaGly: 3.739 ± 0.074	0.996AlaHis: 0.996 ± 0.032	5.206AlaIle: 5.206 ± 0.081	5.087AlaLys: 5.087 ± 0.073	5.611AlaLeu: 5.611 ± 0.09	1.511AlaMet: 1.511 ± 0.04	3.616AlaAsn: 3.616 ± 0.069	1.619AlaPro: 1.619 ± 0.043	2.56AlaGln: 2.56 ± 0.06	1.776AlaArg: 1.776 ± 0.047	3.579AlaSer: 3.579 ± 0.063	3.453AlaThr: 3.453 ± 0.063	3.615AlaVal: 3.615 ± 0.075	0.568AlaTrp: 0.568 ± 0.029	2.327AlaTyr: 2.327 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.395CysAla: 0.395 ± 0.023	0.098CysCys: 0.098 ± 0.011	0.359CysAsp: 0.359 ± 0.02	0.417CysGlu: 0.417 ± 0.021	0.394CysPhe: 0.394 ± 0.026	0.567CysGly: 0.567 ± 0.023	0.157CysHis: 0.157 ± 0.016	0.577CysIle: 0.577 ± 0.027	0.443CysLys: 0.443 ± 0.024	0.586CysLeu: 0.586 ± 0.023	0.136CysMet: 0.136 ± 0.014	0.404CysAsn: 0.404 ± 0.024	0.261CysPro: 0.261 ± 0.02	0.207CysGln: 0.207 ± 0.014	0.184CysArg: 0.184 ± 0.014	0.459CysSer: 0.459 ± 0.019	0.371CysThr: 0.371 ± 0.019	0.417CysVal: 0.417 ± 0.02	0.061CysTrp: 0.061 ± 0.007	0.264CysTyr: 0.264 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.477AspAla: 3.477 ± 0.07	0.354AspCys: 0.354 ± 0.019	3.099AspAsp: 3.099 ± 0.056	4.312AspGlu: 4.312 ± 0.075	3.907AspPhe: 3.907 ± 0.072	3.482AspGly: 3.482 ± 0.063	0.8AspHis: 0.8 ± 0.03	4.291AspIle: 4.291 ± 0.069	4.895AspLys: 4.895 ± 0.068	5.744AspLeu: 5.744 ± 0.073	1.043AspMet: 1.043 ± 0.031	3.43AspAsn: 3.43 ± 0.066	1.544AspPro: 1.544 ± 0.043	1.817AspGln: 1.817 ± 0.043	1.854AspArg: 1.854 ± 0.051	2.908AspSer: 2.908 ± 0.069	2.394AspThr: 2.394 ± 0.059	3.49AspVal: 3.49 ± 0.06	0.717AspTrp: 0.717 ± 0.029	3.106AspTyr: 3.106 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	4.087GluAla: 4.087 ± 0.079	0.333GluCys: 0.333 ± 0.02	3.509GluAsp: 3.509 ± 0.065	4.829GluGlu: 4.829 ± 0.075	3.256GluPhe: 3.256 ± 0.062	3.342GluGly: 3.342 ± 0.07	1.027GluHis: 1.027 ± 0.031	6.451GluIle: 6.451 ± 0.105	6.439GluLys: 6.439 ± 0.093	6.313GluLeu: 6.313 ± 0.085	1.623GluMet: 1.623 ± 0.044	5.45GluAsn: 5.45 ± 0.089	1.424GluPro: 1.424 ± 0.04	2.466GluGln: 2.466 ± 0.048	2.167GluArg: 2.167 ± 0.052	3.084GluSer: 3.084 ± 0.061	3.641GluThr: 3.641 ± 0.065	4.191GluVal: 4.191 ± 0.074	0.605GluTrp: 0.605 ± 0.025	2.593GluTyr: 2.593 ± 0.057	0.0GluXaa: 0.0 ± 0.0
Phe	3.205PheAla: 3.205 ± 0.054	0.449PheCys: 0.449 ± 0.02	3.527PheAsp: 3.527 ± 0.061	3.638PheGlu: 3.638 ± 0.06	2.836PhePhe: 2.836 ± 0.068	3.631PheGly: 3.631 ± 0.073	0.809PheHis: 0.809 ± 0.028	4.506PheIle: 4.506 ± 0.081	3.863PheLys: 3.863 ± 0.07	4.799PheLeu: 4.799 ± 0.086	1.155PheMet: 1.155 ± 0.029	3.37PheAsn: 3.37 ± 0.066	1.752PhePro: 1.752 ± 0.042	1.62PheGln: 1.62 ± 0.036	1.603PheArg: 1.603 ± 0.035	4.049PheSer: 4.049 ± 0.073	3.186PheThr: 3.186 ± 0.053	3.319PheVal: 3.319 ± 0.063	0.554PheTrp: 0.554 ± 0.023	2.411PheTyr: 2.411 ± 0.053	0.0PheXaa: 0.0 ± 0.0
Gly	3.672GlyAla: 3.672 ± 0.081	0.468GlyCys: 0.468 ± 0.024	3.018GlyAsp: 3.018 ± 0.064	3.455GlyGlu: 3.455 ± 0.064	3.512GlyPhe: 3.512 ± 0.072	4.098GlyGly: 4.098 ± 0.093	0.989GlyHis: 0.989 ± 0.036	5.196GlyIle: 5.196 ± 0.087	5.236GlyLys: 5.236 ± 0.092	5.34GlyLeu: 5.34 ± 0.075	1.475GlyMet: 1.475 ± 0.045	3.586GlyAsn: 3.586 ± 0.067	1.116GlyPro: 1.116 ± 0.034	1.939GlyGln: 1.939 ± 0.047	1.802GlyArg: 1.802 ± 0.045	3.587GlySer: 3.587 ± 0.07	3.632GlyThr: 3.632 ± 0.069	4.035GlyVal: 4.035 ± 0.07	0.657GlyTrp: 0.657 ± 0.028	2.734GlyTyr: 2.734 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	0.847HisAla: 0.847 ± 0.031	0.151HisCys: 0.151 ± 0.013	0.796HisAsp: 0.796 ± 0.027	0.914HisGlu: 0.914 ± 0.032	1.085HisPhe: 1.085 ± 0.041	0.915HisGly: 0.915 ± 0.033	0.457HisHis: 0.457 ± 0.021	1.229HisIle: 1.229 ± 0.039	1.073HisLys: 1.073 ± 0.033	1.713HisLeu: 1.713 ± 0.044	0.296HisMet: 0.296 ± 0.019	0.935HisAsn: 0.935 ± 0.03	0.755HisPro: 0.755 ± 0.03	0.883HisGln: 0.883 ± 0.029	0.565HisArg: 0.565 ± 0.022	0.939HisSer: 0.939 ± 0.029	0.764HisThr: 0.764 ± 0.029	0.824HisVal: 0.824 ± 0.031	0.165HisTrp: 0.165 ± 0.014	0.772HisTyr: 0.772 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.471IleAla: 5.471 ± 0.081	0.662IleCys: 0.662 ± 0.026	5.358IleAsp: 5.358 ± 0.076	6.026IleGlu: 6.026 ± 0.09	4.171IlePhe: 4.171 ± 0.074	5.243IleGly: 5.243 ± 0.078	1.336IleHis: 1.336 ± 0.038	6.939IleIle: 6.939 ± 0.11	6.485IleLys: 6.485 ± 0.076	7.823IleLeu: 7.823 ± 0.118	1.392IleMet: 1.392 ± 0.038	5.77IleAsn: 5.77 ± 0.087	3.149IlePro: 3.149 ± 0.057	2.976IleGln: 2.976 ± 0.057	2.399IleArg: 2.399 ± 0.055	5.846IleSer: 5.846 ± 0.084	4.517IleThr: 4.517 ± 0.074	5.226IleVal: 5.226 ± 0.079	0.669IleTrp: 0.669 ± 0.025	3.381IleTyr: 3.381 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	4.738LysAla: 4.738 ± 0.075	0.324LysCys: 0.324 ± 0.017	4.949LysAsp: 4.949 ± 0.084	6.439LysGlu: 6.439 ± 0.086	3.513LysPhe: 3.513 ± 0.066	4.515LysGly: 4.515 ± 0.074	1.243LysHis: 1.243 ± 0.036	7.464LysIle: 7.464 ± 0.093	7.297LysLys: 7.297 ± 0.1	6.918LysLeu: 6.918 ± 0.09	2.324LysMet: 2.324 ± 0.052	6.444LysAsn: 6.444 ± 0.086	2.433LysPro: 2.433 ± 0.055	3.137LysGln: 3.137 ± 0.066	2.577LysArg: 2.577 ± 0.054	4.899LysSer: 4.899 ± 0.069	5.049LysThr: 5.049 ± 0.073	5.122LysVal: 5.122 ± 0.08	0.77LysTrp: 0.77 ± 0.029	3.621LysTyr: 3.621 ± 0.076	0.0LysXaa: 0.0 ± 0.0
Leu	5.672LeuAla: 5.672 ± 0.096	0.592LeuCys: 0.592 ± 0.025	5.279LeuAsp: 5.279 ± 0.081	5.892LeuGlu: 5.892 ± 0.091	4.991LeuPhe: 4.991 ± 0.081	5.515LeuGly: 5.515 ± 0.072	1.371LeuHis: 1.371 ± 0.036	7.64LeuIle: 7.64 ± 0.106	7.953LeuLys: 7.953 ± 0.085	7.77LeuLeu: 7.77 ± 0.11	2.123LeuMet: 2.123 ± 0.044	6.434LeuAsn: 6.434 ± 0.097	3.281LeuPro: 3.281 ± 0.06	3.176LeuGln: 3.176 ± 0.058	2.89LeuArg: 2.89 ± 0.058	6.113LeuSer: 6.113 ± 0.086	5.203LeuThr: 5.203 ± 0.077	5.188LeuVal: 5.188 ± 0.076	0.669LeuTrp: 0.669 ± 0.027	3.267LeuTyr: 3.267 ± 0.066	0.0LeuXaa: 0.0 ± 0.0
Met	1.36MetAla: 1.36 ± 0.037	0.125MetCys: 0.125 ± 0.011	1.151MetAsp: 1.151 ± 0.038	1.203MetGlu: 1.203 ± 0.036	0.941MetPhe: 0.941 ± 0.031	1.208MetGly: 1.208 ± 0.033	0.368MetHis: 0.368 ± 0.02	1.836MetIle: 1.836 ± 0.041	2.399MetLys: 2.399 ± 0.044	1.845MetLeu: 1.845 ± 0.046	0.696MetMet: 0.696 ± 0.031	1.605MetAsn: 1.605 ± 0.041	0.744MetPro: 0.744 ± 0.028	0.814MetGln: 0.814 ± 0.033	0.803MetArg: 0.803 ± 0.026	1.352MetSer: 1.352 ± 0.035	1.15MetThr: 1.15 ± 0.039	1.268MetVal: 1.268 ± 0.038	0.16MetTrp: 0.16 ± 0.012	0.74MetTyr: 0.74 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.768AsnAla: 3.768 ± 0.057	0.413AsnCys: 0.413 ± 0.019	3.701AsnAsp: 3.701 ± 0.072	4.374AsnGlu: 4.374 ± 0.073	3.72AsnPhe: 3.72 ± 0.077	4.096AsnGly: 4.096 ± 0.081	1.187AsnHis: 1.187 ± 0.036	5.197AsnIle: 5.197 ± 0.08	5.132AsnLys: 5.132 ± 0.085	6.2AsnLeu: 6.2 ± 0.088	1.251AsnMet: 1.251 ± 0.036	4.751AsnAsn: 4.751 ± 0.103	2.857AsnPro: 2.857 ± 0.055	3.395AsnGln: 3.395 ± 0.071	2.13AsnArg: 2.13 ± 0.049	4.261AsnSer: 4.261 ± 0.083	3.63AsnThr: 3.63 ± 0.073	3.88AsnVal: 3.88 ± 0.065	0.827AsnTrp: 0.827 ± 0.029	3.46AsnTyr: 3.46 ± 0.073	0.0AsnXaa: 0.0 ± 0.0
Pro	1.803ProAla: 1.803 ± 0.045	0.179ProCys: 0.179 ± 0.015	1.67ProAsp: 1.67 ± 0.043	2.415ProGlu: 2.415 ± 0.053	1.815ProPhe: 1.815 ± 0.049	1.562ProGly: 1.562 ± 0.041	0.532ProHis: 0.532 ± 0.022	3.012ProIle: 3.012 ± 0.057	2.715ProLys: 2.715 ± 0.046	2.593ProLeu: 2.593 ± 0.045	0.715ProMet: 0.715 ± 0.03	2.266ProAsn: 2.266 ± 0.046	0.611ProPro: 0.611 ± 0.028	1.117ProGln: 1.117 ± 0.04	0.783ProArg: 0.783 ± 0.033	1.919ProSer: 1.919 ± 0.044	2.205ProThr: 2.205 ± 0.044	1.904ProVal: 1.904 ± 0.047	0.271ProTrp: 0.271 ± 0.016	1.354ProTyr: 1.354 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	2.16GlnAla: 2.16 ± 0.046	0.135GlnCys: 0.135 ± 0.012	1.859GlnAsp: 1.859 ± 0.042	2.468GlnGlu: 2.468 ± 0.055	1.977GlnPhe: 1.977 ± 0.045	1.72GlnGly: 1.72 ± 0.049	0.644GlnHis: 0.644 ± 0.024	3.184GlnIle: 3.184 ± 0.057	3.275GlnLys: 3.275 ± 0.057	3.775GlnLeu: 3.775 ± 0.071	0.835GlnMet: 0.835 ± 0.03	2.805GlnAsn: 2.805 ± 0.057	1.133GlnPro: 1.133 ± 0.039	1.707GlnGln: 1.707 ± 0.052	1.132GlnArg: 1.132 ± 0.036	2.043GlnSer: 2.043 ± 0.049	2.128GlnThr: 2.128 ± 0.044	2.054GlnVal: 2.054 ± 0.052	0.3GlnTrp: 0.3 ± 0.019	1.517GlnTyr: 1.517 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	1.752ArgAla: 1.752 ± 0.048	0.168ArgCys: 0.168 ± 0.014	1.579ArgAsp: 1.579 ± 0.044	2.006ArgGlu: 2.006 ± 0.049	1.768ArgPhe: 1.768 ± 0.038	1.679ArgGly: 1.679 ± 0.048	0.503ArgHis: 0.503 ± 0.022	2.732ArgIle: 2.732 ± 0.05	2.674ArgLys: 2.674 ± 0.057	3.02ArgLeu: 3.02 ± 0.059	0.785ArgMet: 0.785 ± 0.03	2.092ArgAsn: 2.092 ± 0.05	0.983ArgPro: 0.983 ± 0.031	1.04ArgGln: 1.04 ± 0.037	1.086ArgArg: 1.086 ± 0.031	1.567ArgSer: 1.567 ± 0.044	1.682ArgThr: 1.682 ± 0.044	1.918ArgVal: 1.918 ± 0.046	0.307ArgTrp: 0.307 ± 0.016	1.351ArgTyr: 1.351 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	3.561SerAla: 3.561 ± 0.068	0.602SerCys: 0.602 ± 0.025	3.275SerAsp: 3.275 ± 0.055	3.644SerGlu: 3.644 ± 0.067	3.817SerPhe: 3.817 ± 0.07	3.893SerGly: 3.893 ± 0.076	0.96SerHis: 0.96 ± 0.031	5.456SerIle: 5.456 ± 0.077	5.166SerLys: 5.166 ± 0.082	5.526SerLeu: 5.526 ± 0.075	1.126SerMet: 1.126 ± 0.033	3.911SerAsn: 3.911 ± 0.074	2.003SerPro: 2.003 ± 0.045	2.077SerGln: 2.077 ± 0.047	1.811SerArg: 1.811 ± 0.043	4.139SerSer: 4.139 ± 0.069	3.818SerThr: 3.818 ± 0.059	3.713SerVal: 3.713 ± 0.066	0.619SerTrp: 0.619 ± 0.023	2.67SerTyr: 2.67 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	3.53ThrAla: 3.53 ± 0.066	0.333ThrCys: 0.333 ± 0.02	3.344ThrAsp: 3.344 ± 0.056	3.654ThrGlu: 3.654 ± 0.061	2.97ThrPhe: 2.97 ± 0.059	3.368ThrGly: 3.368 ± 0.064	0.874ThrHis: 0.874 ± 0.03	5.294ThrIle: 5.294 ± 0.082	4.5ThrLys: 4.5 ± 0.067	5.105ThrLeu: 5.105 ± 0.078	0.969ThrMet: 0.969 ± 0.034	3.747ThrAsn: 3.747 ± 0.077	2.12ThrPro: 2.12 ± 0.047	1.89ThrGln: 1.89 ± 0.038	1.513ThrArg: 1.513 ± 0.044	3.612ThrSer: 3.612 ± 0.056	3.536ThrThr: 3.536 ± 0.077	3.385ThrVal: 3.385 ± 0.062	0.505ThrTrp: 0.505 ± 0.024	2.434ThrTyr: 2.434 ± 0.059	0.0ThrXaa: 0.0 ± 0.0
Val	3.79ValAla: 3.79 ± 0.072	0.47ValCys: 0.47 ± 0.023	3.777ValAsp: 3.777 ± 0.06	4.198ValGlu: 4.198 ± 0.078	3.229ValPhe: 3.229 ± 0.063	3.904ValGly: 3.904 ± 0.078	0.889ValHis: 0.889 ± 0.03	4.714ValIle: 4.714 ± 0.071	4.778ValLys: 4.778 ± 0.074	5.488ValLeu: 5.488 ± 0.093	1.291ValMet: 1.291 ± 0.038	3.879ValAsn: 3.879 ± 0.065	1.942ValPro: 1.942 ± 0.044	1.778ValGln: 1.778 ± 0.041	1.84ValArg: 1.84 ± 0.049	4.042ValSer: 4.042 ± 0.062	3.254ValThr: 3.254 ± 0.06	3.993ValVal: 3.993 ± 0.071	0.561ValTrp: 0.561 ± 0.025	2.495ValTyr: 2.495 ± 0.053	0.0ValXaa: 0.0 ± 0.0
Trp	0.534TrpAla: 0.534 ± 0.022	0.079TrpCys: 0.079 ± 0.008	0.527TrpAsp: 0.527 ± 0.023	0.562TrpGlu: 0.562 ± 0.023	0.573TrpPhe: 0.573 ± 0.026	0.564TrpGly: 0.564 ± 0.024	0.172TrpHis: 0.172 ± 0.013	0.847TrpIle: 0.847 ± 0.036	0.835TrpLys: 0.835 ± 0.031	0.837TrpLeu: 0.837 ± 0.032	0.287TrpMet: 0.287 ± 0.019	0.727TrpAsn: 0.727 ± 0.028	0.191TrpPro: 0.191 ± 0.015	0.366TrpGln: 0.366 ± 0.019	0.312TrpArg: 0.312 ± 0.017	0.57TrpSer: 0.57 ± 0.028	0.539TrpThr: 0.539 ± 0.024	0.531TrpVal: 0.531 ± 0.025	0.132TrpTrp: 0.132 ± 0.011	0.371TrpTyr: 0.371 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.347TyrAla: 2.347 ± 0.051	0.328TyrCys: 0.328 ± 0.02	2.532TyrAsp: 2.532 ± 0.047	2.421TyrGlu: 2.421 ± 0.054	2.713TyrPhe: 2.713 ± 0.06	2.506TyrGly: 2.506 ± 0.06	0.764TyrHis: 0.764 ± 0.03	3.072TyrIle: 3.072 ± 0.058	3.533TyrLys: 3.533 ± 0.067	4.016TyrLeu: 4.016 ± 0.064	0.733TyrMet: 0.733 ± 0.025	3.006TyrAsn: 3.006 ± 0.078	1.524TyrPro: 1.524 ± 0.047	1.888TyrGln: 1.888 ± 0.048	1.466TyrArg: 1.466 ± 0.044	2.82TyrSer: 2.82 ± 0.056	2.527TyrThr: 2.527 ± 0.057	2.238TyrVal: 2.238 ± 0.049	0.439TyrTrp: 0.439 ± 0.026	2.045TyrTyr: 2.045 ± 0.049	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3034 proteins (983139 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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