Amino acid dipepetide frequency for Tortoise microvirus 80

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.312AlaAla: 2.312 ± 0.915
1.156AlaCys: 1.156 ± 1.155
4.046AlaAsp: 4.046 ± 1.619
5.78AlaGlu: 5.78 ± 3.072
4.624AlaPhe: 4.624 ± 2.657
4.624AlaGly: 4.624 ± 1.816
2.312AlaHis: 2.312 ± 1.825
2.312AlaIle: 2.312 ± 0.899
4.624AlaLys: 4.624 ± 1.699
6.936AlaLeu: 6.936 ± 1.693
0.578AlaMet: 0.578 ± 0.577
2.89AlaAsn: 2.89 ± 0.858
5.78AlaPro: 5.78 ± 2.491
3.468AlaGln: 3.468 ± 1.714
1.156AlaArg: 1.156 ± 0.831
5.78AlaSer: 5.78 ± 2.464
5.202AlaThr: 5.202 ± 1.674
6.936AlaVal: 6.936 ± 1.597
0.0AlaTrp: 0.0 ± 0.0
3.468AlaTyr: 3.468 ± 1.055
0.0AlaXaa: 0.0 ± 0.0
Cys
1.156CysAla: 1.156 ± 0.992
0.0CysCys: 0.0 ± 0.0
0.578CysAsp: 0.578 ± 0.446
0.0CysGlu: 0.0 ± 0.0
1.156CysPhe: 1.156 ± 0.953
0.578CysGly: 0.578 ± 0.577
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.156CysLys: 1.156 ± 1.155
0.578CysLeu: 0.578 ± 0.577
0.0CysMet: 0.0 ± 0.0
0.578CysAsn: 0.578 ± 0.875
0.578CysPro: 0.578 ± 0.746
0.578CysGln: 0.578 ± 0.801
1.734CysArg: 1.734 ± 1.049
1.156CysSer: 1.156 ± 1.224
1.734CysThr: 1.734 ± 1.442
1.734CysVal: 1.734 ± 1.778
0.0CysTrp: 0.0 ± 0.0
1.156CysTyr: 1.156 ± 0.992
0.0CysXaa: 0.0 ± 0.0
Asp
2.89AspAla: 2.89 ± 1.346
1.156AspCys: 1.156 ± 0.562
5.78AspAsp: 5.78 ± 2.397
4.046AspGlu: 4.046 ± 2.169
5.202AspPhe: 5.202 ± 1.859
2.312AspGly: 2.312 ± 0.915
0.578AspHis: 0.578 ± 0.446
3.468AspIle: 3.468 ± 0.909
3.468AspLys: 3.468 ± 1.796
6.358AspLeu: 6.358 ± 1.252
1.156AspMet: 1.156 ± 0.931
3.468AspAsn: 3.468 ± 1.216
2.89AspPro: 2.89 ± 0.792
1.156AspGln: 1.156 ± 0.695
3.468AspArg: 3.468 ± 1.592
5.202AspSer: 5.202 ± 1.356
2.89AspThr: 2.89 ± 0.909
3.468AspVal: 3.468 ± 2.155
1.156AspTrp: 1.156 ± 0.863
3.468AspTyr: 3.468 ± 1.522
0.0AspXaa: 0.0 ± 0.0
Glu
5.202GluAla: 5.202 ± 2.539
0.0GluCys: 0.0 ± 0.0
1.156GluAsp: 1.156 ± 1.07
3.468GluGlu: 3.468 ± 2.076
2.312GluPhe: 2.312 ± 0.892
0.0GluGly: 0.0 ± 0.0
1.156GluHis: 1.156 ± 0.953
3.468GluIle: 3.468 ± 1.471
2.312GluLys: 2.312 ± 1.091
7.514GluLeu: 7.514 ± 1.834
2.312GluMet: 2.312 ± 0.865
4.046GluAsn: 4.046 ± 2.15
0.0GluPro: 0.0 ± 0.0
2.312GluGln: 2.312 ± 1.613
2.89GluArg: 2.89 ± 1.912
2.89GluSer: 2.89 ± 1.912
2.312GluThr: 2.312 ± 1.142
3.468GluVal: 3.468 ± 2.328
0.578GluTrp: 0.578 ± 0.757
2.89GluTyr: 2.89 ± 1.478
0.0GluXaa: 0.0 ± 0.0
Phe
5.202PheAla: 5.202 ± 2.076
1.156PheCys: 1.156 ± 1.155
7.514PheAsp: 7.514 ± 2.48
3.468PheGlu: 3.468 ± 1.029
3.468PhePhe: 3.468 ± 1.471
4.046PheGly: 4.046 ± 1.053
0.578PheHis: 0.578 ± 0.801
4.046PheIle: 4.046 ± 0.985
1.156PheLys: 1.156 ± 0.562
4.624PheLeu: 4.624 ± 1.276
0.578PheMet: 0.578 ± 0.446
2.312PheAsn: 2.312 ± 0.837
3.468PhePro: 3.468 ± 1.731
1.734PheGln: 1.734 ± 1.013
1.734PheArg: 1.734 ± 1.006
4.624PheSer: 4.624 ± 1.85
1.156PheThr: 1.156 ± 0.571
1.156PheVal: 1.156 ± 0.863
0.578PheTrp: 0.578 ± 0.446
1.156PheTyr: 1.156 ± 0.84
0.0PheXaa: 0.0 ± 0.0
Gly
2.312GlyAla: 2.312 ± 1.124
0.578GlyCys: 0.578 ± 0.577
2.89GlyAsp: 2.89 ± 1.128
0.578GlyGlu: 0.578 ± 0.577
1.156GlyPhe: 1.156 ± 1.071
1.156GlyGly: 1.156 ± 0.571
0.578GlyHis: 0.578 ± 0.446
3.468GlyIle: 3.468 ± 1.331
2.312GlyLys: 2.312 ± 1.151
6.358GlyLeu: 6.358 ± 1.242
0.578GlyMet: 0.578 ± 0.446
1.156GlyAsn: 1.156 ± 0.85
0.578GlyPro: 0.578 ± 0.446
1.734GlyGln: 1.734 ± 0.765
3.468GlyArg: 3.468 ± 1.211
6.936GlySer: 6.936 ± 2.532
6.358GlyThr: 6.358 ± 1.592
4.046GlyVal: 4.046 ± 0.862
0.0GlyTrp: 0.0 ± 0.0
4.046GlyTyr: 4.046 ± 1.498
0.0GlyXaa: 0.0 ± 0.0
His
1.156HisAla: 1.156 ± 0.831
1.156HisCys: 1.156 ± 0.992
1.156HisAsp: 1.156 ± 1.071
1.734HisGlu: 1.734 ± 1.049
0.578HisPhe: 0.578 ± 0.446
3.468HisGly: 3.468 ± 1.539
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.578HisLys: 0.578 ± 0.535
1.734HisLeu: 1.734 ± 0.834
0.578HisMet: 0.578 ± 0.535
1.156HisAsn: 1.156 ± 1.155
0.578HisPro: 0.578 ± 0.446
0.578HisGln: 0.578 ± 0.446
0.0HisArg: 0.0 ± 0.0
1.734HisSer: 1.734 ± 0.923
0.578HisThr: 0.578 ± 0.446
2.312HisVal: 2.312 ± 1.114
0.0HisTrp: 0.0 ± 0.0
0.578HisTyr: 0.578 ± 0.577
0.0HisXaa: 0.0 ± 0.0
Ile
3.468IleAla: 3.468 ± 1.011
0.0IleCys: 0.0 ± 0.0
2.312IleAsp: 2.312 ± 1.663
3.468IleGlu: 3.468 ± 2.502
2.312IlePhe: 2.312 ± 1.142
0.578IleGly: 0.578 ± 0.446
1.156IleHis: 1.156 ± 1.07
1.734IleIle: 1.734 ± 1.316
1.734IleLys: 1.734 ± 1.239
2.312IleLeu: 2.312 ± 1.117
0.578IleMet: 0.578 ± 0.715
4.046IleAsn: 4.046 ± 0.826
4.624IlePro: 4.624 ± 1.272
2.312IleGln: 2.312 ± 1.142
3.468IleArg: 3.468 ± 1.872
5.202IleSer: 5.202 ± 2.238
1.734IleThr: 1.734 ± 0.554
1.734IleVal: 1.734 ± 1.201
1.156IleTrp: 1.156 ± 0.892
2.312IleTyr: 2.312 ± 1.819
0.0IleXaa: 0.0 ± 0.0
Lys
1.734LysAla: 1.734 ± 1.098
1.156LysCys: 1.156 ± 1.103
2.89LysAsp: 2.89 ± 0.845
2.89LysGlu: 2.89 ± 1.311
1.156LysPhe: 1.156 ± 1.07
2.312LysGly: 2.312 ± 0.977
0.0LysHis: 0.0 ± 0.0
2.312LysIle: 2.312 ± 2.191
3.468LysLys: 3.468 ± 1.777
5.202LysLeu: 5.202 ± 1.856
2.312LysMet: 2.312 ± 0.993
2.312LysAsn: 2.312 ± 0.727
2.89LysPro: 2.89 ± 1.199
3.468LysGln: 3.468 ± 1.79
3.468LysArg: 3.468 ± 1.667
2.89LysSer: 2.89 ± 0.944
4.046LysThr: 4.046 ± 1.31
1.156LysVal: 1.156 ± 1.155
0.578LysTrp: 0.578 ± 0.535
1.734LysTyr: 1.734 ± 1.372
0.0LysXaa: 0.0 ± 0.0
Leu
5.202LeuAla: 5.202 ± 1.798
1.156LeuCys: 1.156 ± 0.977
4.624LeuAsp: 4.624 ± 1.992
5.78LeuGlu: 5.78 ± 1.929
4.046LeuPhe: 4.046 ± 2.191
6.936LeuGly: 6.936 ± 1.65
1.734LeuHis: 1.734 ± 0.762
5.202LeuIle: 5.202 ± 1.772
2.89LeuLys: 2.89 ± 1.448
6.936LeuLeu: 6.936 ± 1.378
2.312LeuMet: 2.312 ± 1.016
7.514LeuAsn: 7.514 ± 2.766
8.671LeuPro: 8.671 ± 2.533
3.468LeuGln: 3.468 ± 1.18
4.624LeuArg: 4.624 ± 2.108
10.983LeuSer: 10.983 ± 2.885
5.78LeuThr: 5.78 ± 2.864
2.89LeuVal: 2.89 ± 1.382
0.578LeuTrp: 0.578 ± 0.446
1.734LeuTyr: 1.734 ± 1.201
0.0LeuXaa: 0.0 ± 0.0
Met
3.468MetAla: 3.468 ± 1.833
0.578MetCys: 0.578 ± 0.801
2.312MetAsp: 2.312 ± 1.214
0.0MetGlu: 0.0 ± 0.0
1.156MetPhe: 1.156 ± 0.708
0.578MetGly: 0.578 ± 0.577
0.0MetHis: 0.0 ± 0.0
0.578MetIle: 0.578 ± 0.875
1.156MetLys: 1.156 ± 0.766
2.312MetLeu: 2.312 ± 1.661
1.734MetMet: 1.734 ± 1.58
1.156MetAsn: 1.156 ± 0.571
0.578MetPro: 0.578 ± 0.535
0.578MetGln: 0.578 ± 0.535
1.156MetArg: 1.156 ± 0.892
1.734MetSer: 1.734 ± 0.554
3.468MetThr: 3.468 ± 0.75
0.0MetVal: 0.0 ± 0.0
1.734MetTrp: 1.734 ± 0.792
1.734MetTyr: 1.734 ± 0.834
0.0MetXaa: 0.0 ± 0.0
Asn
6.936AsnAla: 6.936 ± 2.122
1.156AsnCys: 1.156 ± 0.953
2.312AsnAsp: 2.312 ± 1.265
1.156AsnGlu: 1.156 ± 0.892
4.624AsnPhe: 4.624 ± 2.221
0.578AsnGly: 0.578 ± 0.757
0.578AsnHis: 0.578 ± 0.577
1.734AsnIle: 1.734 ± 1.089
2.312AsnLys: 2.312 ± 1.265
3.468AsnLeu: 3.468 ± 1.02
0.578AsnMet: 0.578 ± 0.446
0.578AsnAsn: 0.578 ± 0.535
3.468AsnPro: 3.468 ± 1.502
2.89AsnGln: 2.89 ± 1.175
1.734AsnArg: 1.734 ± 0.554
3.468AsnSer: 3.468 ± 1.022
3.468AsnThr: 3.468 ± 1.748
4.624AsnVal: 4.624 ± 1.402
0.578AsnTrp: 0.578 ± 0.801
2.312AsnTyr: 2.312 ± 1.6
0.0AsnXaa: 0.0 ± 0.0
Pro
5.78ProAla: 5.78 ± 3.181
0.578ProCys: 0.578 ± 0.746
3.468ProAsp: 3.468 ± 1.522
1.156ProGlu: 1.156 ± 1.19
3.468ProPhe: 3.468 ± 1.312
0.0ProGly: 0.0 ± 0.0
1.156ProHis: 1.156 ± 0.695
4.046ProIle: 4.046 ± 1.532
0.578ProLys: 0.578 ± 0.801
6.936ProLeu: 6.936 ± 2.147
0.578ProMet: 0.578 ± 0.446
2.312ProAsn: 2.312 ± 1.784
0.0ProPro: 0.0 ± 0.0
4.046ProGln: 4.046 ± 0.944
1.156ProArg: 1.156 ± 0.571
7.514ProSer: 7.514 ± 3.129
3.468ProThr: 3.468 ± 1.523
5.202ProVal: 5.202 ± 1.695
0.0ProTrp: 0.0 ± 0.0
2.312ProTyr: 2.312 ± 1.214
0.0ProXaa: 0.0 ± 0.0
Gln
2.312GlnAla: 2.312 ± 1.076
0.0GlnCys: 0.0 ± 0.0
1.156GlnAsp: 1.156 ± 0.855
0.578GlnGlu: 0.578 ± 0.721
4.624GlnPhe: 4.624 ± 1.088
2.312GlnGly: 2.312 ± 1.059
1.156GlnHis: 1.156 ± 0.695
1.734GlnIle: 1.734 ± 0.554
3.468GlnLys: 3.468 ± 1.719
2.312GlnLeu: 2.312 ± 1.142
2.312GlnMet: 2.312 ± 1.613
4.046GlnAsn: 4.046 ± 1.989
1.734GlnPro: 1.734 ± 1.564
2.89GlnGln: 2.89 ± 2.676
4.046GlnArg: 4.046 ± 1.081
4.046GlnSer: 4.046 ± 2.031
4.046GlnThr: 4.046 ± 2.128
2.312GlnVal: 2.312 ± 1.574
1.156GlnTrp: 1.156 ± 0.695
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.468ArgAla: 3.468 ± 0.989
0.578ArgCys: 0.578 ± 0.746
2.89ArgAsp: 2.89 ± 1.387
3.468ArgGlu: 3.468 ± 0.843
2.89ArgPhe: 2.89 ± 1.307
3.468ArgGly: 3.468 ± 1.44
1.734ArgHis: 1.734 ± 1.161
2.89ArgIle: 2.89 ± 1.792
3.468ArgLys: 3.468 ± 1.719
4.624ArgLeu: 4.624 ± 1.107
1.734ArgMet: 1.734 ± 1.048
1.156ArgAsn: 1.156 ± 0.992
2.312ArgPro: 2.312 ± 1.124
2.312ArgGln: 2.312 ± 0.809
3.468ArgArg: 3.468 ± 1.732
4.046ArgSer: 4.046 ± 1.394
1.734ArgThr: 1.734 ± 1.049
2.312ArgVal: 2.312 ± 1.424
0.0ArgTrp: 0.0 ± 0.0
3.468ArgTyr: 3.468 ± 0.791
0.0ArgXaa: 0.0 ± 0.0
Ser
6.358SerAla: 6.358 ± 3.242
1.734SerCys: 1.734 ± 0.869
4.046SerAsp: 4.046 ± 1.639
4.624SerGlu: 4.624 ± 2.101
3.468SerPhe: 3.468 ± 1.199
7.514SerGly: 7.514 ± 2.492
2.89SerHis: 2.89 ± 1.039
4.624SerIle: 4.624 ± 1.266
6.358SerLys: 6.358 ± 2.428
8.092SerLeu: 8.092 ± 2.785
2.89SerMet: 2.89 ± 0.677
2.89SerAsn: 2.89 ± 1.14
4.624SerPro: 4.624 ± 1.674
2.89SerGln: 2.89 ± 1.146
4.624SerArg: 4.624 ± 1.679
6.936SerSer: 6.936 ± 2.849
5.78SerThr: 5.78 ± 1.765
3.468SerVal: 3.468 ± 1.527
0.578SerTrp: 0.578 ± 0.577
3.468SerTyr: 3.468 ± 1.789
0.0SerXaa: 0.0 ± 0.0
Thr
8.092ThrAla: 8.092 ± 2.258
0.0ThrCys: 0.0 ± 0.0
4.046ThrAsp: 4.046 ± 1.257
4.624ThrGlu: 4.624 ± 2.562
2.89ThrPhe: 2.89 ± 1.683
4.624ThrGly: 4.624 ± 1.357
1.156ThrHis: 1.156 ± 0.562
2.89ThrIle: 2.89 ± 1.746
3.468ThrLys: 3.468 ± 1.543
6.936ThrLeu: 6.936 ± 2.27
0.578ThrMet: 0.578 ± 0.446
2.89ThrAsn: 2.89 ± 0.966
4.624ThrPro: 4.624 ± 2.306
1.156ThrGln: 1.156 ± 0.571
1.734ThrArg: 1.734 ± 1.013
4.046ThrSer: 4.046 ± 1.177
4.624ThrThr: 4.624 ± 2.273
0.578ThrVal: 0.578 ± 0.446
0.0ThrTrp: 0.0 ± 0.0
4.624ThrTyr: 4.624 ± 1.34
0.0ThrXaa: 0.0 ± 0.0
Val
4.624ValAla: 4.624 ± 1.369
1.156ValCys: 1.156 ± 1.224
6.358ValAsp: 6.358 ± 2.407
1.734ValGlu: 1.734 ± 1.173
1.156ValPhe: 1.156 ± 1.08
2.312ValGly: 2.312 ± 0.877
1.156ValHis: 1.156 ± 0.892
1.156ValIle: 1.156 ± 0.84
1.734ValLys: 1.734 ± 1.259
6.358ValLeu: 6.358 ± 1.831
1.156ValMet: 1.156 ± 0.84
2.89ValAsn: 2.89 ± 1.602
5.202ValPro: 5.202 ± 1.609
2.312ValGln: 2.312 ± 1.22
4.624ValArg: 4.624 ± 1.241
5.202ValSer: 5.202 ± 2.061
1.734ValThr: 1.734 ± 1.184
4.046ValVal: 4.046 ± 1.404
0.0ValTrp: 0.0 ± 0.0
0.578ValTyr: 0.578 ± 0.446
0.0ValXaa: 0.0 ± 0.0
Trp
0.578TrpAla: 0.578 ± 0.535
0.0TrpCys: 0.0 ± 0.0
1.156TrpAsp: 1.156 ± 1.514
0.578TrpGlu: 0.578 ± 0.577
0.578TrpPhe: 0.578 ± 0.446
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.734TrpLys: 1.734 ± 1.663
0.578TrpLeu: 0.578 ± 0.577
0.0TrpMet: 0.0 ± 0.0
0.578TrpAsn: 0.578 ± 0.446
0.0TrpPro: 0.0 ± 0.0
0.578TrpGln: 0.578 ± 0.535
1.156TrpArg: 1.156 ± 0.562
1.156TrpSer: 1.156 ± 0.562
0.578TrpThr: 0.578 ± 0.535
0.578TrpVal: 0.578 ± 0.446
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.734TyrAla: 1.734 ± 1.013
1.156TyrCys: 1.156 ± 0.992
2.89TyrAsp: 2.89 ± 2.08
1.156TyrGlu: 1.156 ± 0.931
2.89TyrPhe: 2.89 ± 1.593
2.89TyrGly: 2.89 ± 1.096
1.734TyrHis: 1.734 ± 0.869
0.578TyrIle: 0.578 ± 0.446
0.0TyrLys: 0.0 ± 0.0
2.89TyrLeu: 2.89 ± 1.165
2.89TyrMet: 2.89 ± 0.767
0.578TyrAsn: 0.578 ± 0.577
1.156TyrPro: 1.156 ± 0.953
5.78TyrGln: 5.78 ± 1.44
2.312TyrArg: 2.312 ± 0.915
2.312TyrSer: 2.312 ± 1.784
2.89TyrThr: 2.89 ± 1.813
3.468TyrVal: 3.468 ± 0.961
1.156TyrTrp: 1.156 ± 1.155
2.89TyrTyr: 2.89 ± 1.545
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1731 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski