Amino acid dipepetide frequency for Acidianus bottle-shaped virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.692AlaCys: 0.692 ± 0.349
2.075AlaAsp: 2.075 ± 0.501
2.19AlaGlu: 2.19 ± 0.461
2.767AlaPhe: 2.767 ± 0.537
1.268AlaGly: 1.268 ± 0.36
0.692AlaHis: 0.692 ± 0.328
4.266AlaIle: 4.266 ± 0.68
3.459AlaLys: 3.459 ± 0.67
5.995AlaLeu: 5.995 ± 0.955
1.845AlaMet: 1.845 ± 0.516
2.075AlaAsn: 2.075 ± 0.521
1.268AlaPro: 1.268 ± 0.449
1.96AlaGln: 1.96 ± 0.494
1.038AlaArg: 1.038 ± 0.275
1.96AlaSer: 1.96 ± 0.536
1.614AlaThr: 1.614 ± 0.315
2.767AlaVal: 2.767 ± 0.559
0.115AlaTrp: 0.115 ± 0.117
2.997AlaTyr: 2.997 ± 0.598
0.0AlaXaa: 0.0 ± 0.0
Cys
0.231CysAla: 0.231 ± 0.139
0.576CysCys: 0.576 ± 0.31
0.922CysAsp: 0.922 ± 0.319
0.231CysGlu: 0.231 ± 0.142
1.153CysPhe: 1.153 ± 0.365
0.692CysGly: 0.692 ± 0.331
0.346CysHis: 0.346 ± 0.19
0.807CysIle: 0.807 ± 0.501
1.499CysLys: 1.499 ± 0.45
1.614CysLeu: 1.614 ± 0.509
0.0CysMet: 0.0 ± 0.0
0.692CysAsn: 0.692 ± 0.287
1.268CysPro: 1.268 ± 0.459
0.461CysGln: 0.461 ± 0.28
0.692CysArg: 0.692 ± 0.25
0.922CysSer: 0.922 ± 0.273
0.692CysThr: 0.692 ± 0.261
1.038CysVal: 1.038 ± 0.388
0.115CysTrp: 0.115 ± 0.107
1.729CysTyr: 1.729 ± 0.415
0.0CysXaa: 0.0 ± 0.0
Asp
2.882AspAla: 2.882 ± 0.615
0.692AspCys: 0.692 ± 0.284
1.845AspAsp: 1.845 ± 0.438
3.92AspGlu: 3.92 ± 0.81
2.306AspPhe: 2.306 ± 0.489
1.383AspGly: 1.383 ± 0.449
0.922AspHis: 0.922 ± 0.308
2.421AspIle: 2.421 ± 0.634
5.88AspLys: 5.88 ± 1.035
5.303AspLeu: 5.303 ± 0.7
0.807AspMet: 0.807 ± 0.333
2.767AspAsn: 2.767 ± 0.607
2.075AspPro: 2.075 ± 0.415
1.845AspGln: 1.845 ± 0.448
1.729AspArg: 1.729 ± 0.512
3.343AspSer: 3.343 ± 0.639
2.536AspThr: 2.536 ± 0.484
2.997AspVal: 2.997 ± 0.546
0.576AspTrp: 0.576 ± 0.345
4.15AspTyr: 4.15 ± 0.865
0.0AspXaa: 0.0 ± 0.0
Glu
2.652GluAla: 2.652 ± 0.574
1.383GluCys: 1.383 ± 0.453
3.343GluAsp: 3.343 ± 0.626
6.226GluGlu: 6.226 ± 1.038
2.882GluPhe: 2.882 ± 0.566
2.306GluGly: 2.306 ± 0.591
0.922GluHis: 0.922 ± 0.355
8.647GluIle: 8.647 ± 1.25
8.762GluLys: 8.762 ± 1.425
7.378GluLeu: 7.378 ± 0.619
2.421GluMet: 2.421 ± 0.621
5.188GluAsn: 5.188 ± 0.948
1.729GluPro: 1.729 ± 0.382
3.343GluGln: 3.343 ± 0.638
2.536GluArg: 2.536 ± 0.631
3.689GluSer: 3.689 ± 0.61
3.459GluThr: 3.459 ± 0.698
5.418GluVal: 5.418 ± 0.862
0.807GluTrp: 0.807 ± 0.271
3.228GluTyr: 3.228 ± 0.684
0.0GluXaa: 0.0 ± 0.0
Phe
2.882PheAla: 2.882 ± 0.523
1.038PheCys: 1.038 ± 0.416
2.652PheAsp: 2.652 ± 0.561
4.611PheGlu: 4.611 ± 0.655
2.767PhePhe: 2.767 ± 0.66
1.96PheGly: 1.96 ± 0.469
1.038PheHis: 1.038 ± 0.375
5.303PheIle: 5.303 ± 0.802
2.767PheLys: 2.767 ± 0.57
5.188PheLeu: 5.188 ± 0.869
1.038PheMet: 1.038 ± 0.34
4.266PheAsn: 4.266 ± 0.55
2.075PhePro: 2.075 ± 0.47
0.692PheGln: 0.692 ± 0.238
1.153PheArg: 1.153 ± 0.338
4.15PheSer: 4.15 ± 0.62
2.997PheThr: 2.997 ± 0.603
2.997PheVal: 2.997 ± 0.548
0.461PheTrp: 0.461 ± 0.218
1.499PheTyr: 1.499 ± 0.403
0.0PheXaa: 0.0 ± 0.0
Gly
1.038GlyAla: 1.038 ± 0.462
0.807GlyCys: 0.807 ± 0.369
1.96GlyAsp: 1.96 ± 0.544
3.343GlyGlu: 3.343 ± 0.619
2.421GlyPhe: 2.421 ± 0.598
1.614GlyGly: 1.614 ± 0.583
0.692GlyHis: 0.692 ± 0.226
5.764GlyIle: 5.764 ± 0.953
3.343GlyLys: 3.343 ± 0.585
5.303GlyLeu: 5.303 ± 0.843
1.038GlyMet: 1.038 ± 0.311
2.652GlyAsn: 2.652 ± 0.64
0.0GlyPro: 0.0 ± 0.0
0.922GlyGln: 0.922 ± 0.323
0.807GlyArg: 0.807 ± 0.256
1.499GlySer: 1.499 ± 0.357
1.038GlyThr: 1.038 ± 0.311
2.536GlyVal: 2.536 ± 0.566
0.346GlyTrp: 0.346 ± 0.22
2.767GlyTyr: 2.767 ± 0.624
0.0GlyXaa: 0.0 ± 0.0
His
0.461HisAla: 0.461 ± 0.221
0.115HisCys: 0.115 ± 0.118
0.692HisAsp: 0.692 ± 0.271
0.922HisGlu: 0.922 ± 0.268
0.576HisPhe: 0.576 ± 0.223
0.576HisGly: 0.576 ± 0.266
0.231HisHis: 0.231 ± 0.156
0.807HisIle: 0.807 ± 0.28
1.383HisLys: 1.383 ± 0.54
1.845HisLeu: 1.845 ± 0.425
0.231HisMet: 0.231 ± 0.175
0.692HisAsn: 0.692 ± 0.301
0.461HisPro: 0.461 ± 0.236
0.115HisGln: 0.115 ± 0.116
0.231HisArg: 0.231 ± 0.145
1.383HisSer: 1.383 ± 0.454
1.038HisThr: 1.038 ± 0.268
1.038HisVal: 1.038 ± 0.363
0.0HisTrp: 0.0 ± 0.0
1.038HisTyr: 1.038 ± 0.343
0.0HisXaa: 0.0 ± 0.0
Ile
5.303IleAla: 5.303 ± 0.788
0.922IleCys: 0.922 ± 0.4
3.459IleAsp: 3.459 ± 0.597
7.724IleGlu: 7.724 ± 0.899
3.689IlePhe: 3.689 ± 0.694
4.381IleGly: 4.381 ± 0.886
1.268IleHis: 1.268 ± 0.298
8.07IleIle: 8.07 ± 1.035
7.955IleLys: 7.955 ± 1.085
9.915IleLeu: 9.915 ± 1.259
1.499IleMet: 1.499 ± 0.426
6.341IleAsn: 6.341 ± 0.711
4.842IlePro: 4.842 ± 0.861
3.113IleGln: 3.113 ± 0.735
1.614IleArg: 1.614 ± 0.476
5.88IleSer: 5.88 ± 0.828
4.611IleThr: 4.611 ± 0.713
5.995IleVal: 5.995 ± 0.926
0.346IleTrp: 0.346 ± 0.186
5.534IleTyr: 5.534 ± 0.61
0.0IleXaa: 0.0 ± 0.0
Lys
2.997LysAla: 2.997 ± 0.566
0.576LysCys: 0.576 ± 0.252
5.188LysAsp: 5.188 ± 0.816
9.569LysGlu: 9.569 ± 1.38
4.381LysPhe: 4.381 ± 0.657
3.459LysGly: 3.459 ± 0.66
0.692LysHis: 0.692 ± 0.254
8.185LysIle: 8.185 ± 1.01
7.84LysLys: 7.84 ± 1.272
10.261LysLeu: 10.261 ± 1.411
2.306LysMet: 2.306 ± 0.462
3.459LysAsn: 3.459 ± 0.49
2.652LysPro: 2.652 ± 0.683
3.689LysGln: 3.689 ± 0.688
3.689LysArg: 3.689 ± 0.654
2.767LysSer: 2.767 ± 0.59
3.574LysThr: 3.574 ± 0.853
5.534LysVal: 5.534 ± 0.682
1.038LysTrp: 1.038 ± 0.432
4.381LysTyr: 4.381 ± 0.753
0.0LysXaa: 0.0 ± 0.0
Leu
4.842LeuAla: 4.842 ± 0.78
1.845LeuCys: 1.845 ± 0.681
4.727LeuAsp: 4.727 ± 0.695
7.033LeuGlu: 7.033 ± 0.897
6.226LeuPhe: 6.226 ± 1.087
4.957LeuGly: 4.957 ± 0.743
1.499LeuHis: 1.499 ± 0.419
11.759LeuIle: 11.759 ± 1.262
8.877LeuLys: 8.877 ± 0.988
11.99LeuLeu: 11.99 ± 1.211
2.19LeuMet: 2.19 ± 0.446
6.11LeuAsn: 6.11 ± 0.876
5.303LeuPro: 5.303 ± 0.995
3.804LeuGln: 3.804 ± 0.74
2.997LeuArg: 2.997 ± 0.687
7.148LeuSer: 7.148 ± 1.222
7.148LeuThr: 7.148 ± 0.888
7.263LeuVal: 7.263 ± 0.828
0.692LeuTrp: 0.692 ± 0.28
5.188LeuTyr: 5.188 ± 0.806
0.0LeuXaa: 0.0 ± 0.0
Met
1.96MetAla: 1.96 ± 0.681
0.231MetCys: 0.231 ± 0.154
1.153MetAsp: 1.153 ± 0.35
1.383MetGlu: 1.383 ± 0.411
1.038MetPhe: 1.038 ± 0.313
0.807MetGly: 0.807 ± 0.271
0.346MetHis: 0.346 ± 0.173
1.96MetIle: 1.96 ± 0.484
2.536MetLys: 2.536 ± 0.637
2.075MetLeu: 2.075 ± 0.526
0.461MetMet: 0.461 ± 0.231
1.499MetAsn: 1.499 ± 0.392
1.038MetPro: 1.038 ± 0.365
0.922MetGln: 0.922 ± 0.358
1.038MetArg: 1.038 ± 0.309
1.268MetSer: 1.268 ± 0.457
1.153MetThr: 1.153 ± 0.415
0.692MetVal: 0.692 ± 0.28
0.115MetTrp: 0.115 ± 0.112
0.576MetTyr: 0.576 ± 0.214
0.0MetXaa: 0.0 ± 0.0
Asn
2.652AsnAla: 2.652 ± 0.434
0.807AsnCys: 0.807 ± 0.335
2.652AsnAsp: 2.652 ± 0.619
5.534AsnGlu: 5.534 ± 0.905
2.536AsnPhe: 2.536 ± 0.41
3.113AsnGly: 3.113 ± 0.687
0.807AsnHis: 0.807 ± 0.321
2.767AsnIle: 2.767 ± 0.718
4.842AsnLys: 4.842 ± 0.72
6.687AsnLeu: 6.687 ± 0.739
0.576AsnMet: 0.576 ± 0.224
3.459AsnAsn: 3.459 ± 0.678
2.306AsnPro: 2.306 ± 0.463
1.845AsnGln: 1.845 ± 0.431
1.614AsnArg: 1.614 ± 0.457
3.574AsnSer: 3.574 ± 0.687
3.228AsnThr: 3.228 ± 0.52
3.804AsnVal: 3.804 ± 0.597
0.576AsnTrp: 0.576 ± 0.326
3.574AsnTyr: 3.574 ± 0.688
0.0AsnXaa: 0.0 ± 0.0
Pro
1.614ProAla: 1.614 ± 0.369
0.922ProCys: 0.922 ± 0.305
3.113ProAsp: 3.113 ± 0.617
3.113ProGlu: 3.113 ± 0.612
1.96ProPhe: 1.96 ± 0.507
0.922ProGly: 0.922 ± 0.355
0.576ProHis: 0.576 ± 0.229
2.997ProIle: 2.997 ± 0.502
3.574ProLys: 3.574 ± 0.783
3.459ProLeu: 3.459 ± 0.68
0.922ProMet: 0.922 ± 0.444
2.19ProAsn: 2.19 ± 0.522
2.652ProPro: 2.652 ± 0.819
2.421ProGln: 2.421 ± 0.623
0.922ProArg: 0.922 ± 0.305
2.882ProSer: 2.882 ± 0.657
1.729ProThr: 1.729 ± 0.484
2.882ProVal: 2.882 ± 0.665
0.115ProTrp: 0.115 ± 0.118
2.652ProTyr: 2.652 ± 0.466
0.0ProXaa: 0.0 ± 0.0
Gln
1.268GlnAla: 1.268 ± 0.363
0.922GlnCys: 0.922 ± 0.383
1.729GlnAsp: 1.729 ± 0.506
2.882GlnGlu: 2.882 ± 0.515
1.96GlnPhe: 1.96 ± 0.492
1.268GlnGly: 1.268 ± 0.336
0.346GlnHis: 0.346 ± 0.174
2.882GlnIle: 2.882 ± 0.542
3.113GlnLys: 3.113 ± 0.703
3.459GlnLeu: 3.459 ± 0.655
0.692GlnMet: 0.692 ± 0.255
2.997GlnAsn: 2.997 ± 0.91
2.306GlnPro: 2.306 ± 0.551
0.807GlnGln: 0.807 ± 0.535
1.153GlnArg: 1.153 ± 0.387
1.729GlnSer: 1.729 ± 0.504
1.383GlnThr: 1.383 ± 0.379
2.536GlnVal: 2.536 ± 0.557
0.115GlnTrp: 0.115 ± 0.113
1.153GlnTyr: 1.153 ± 0.322
0.0GlnXaa: 0.0 ± 0.0
Arg
0.692ArgAla: 0.692 ± 0.327
0.115ArgCys: 0.115 ± 0.113
1.729ArgAsp: 1.729 ± 0.573
1.153ArgGlu: 1.153 ± 0.348
1.614ArgPhe: 1.614 ± 0.4
1.729ArgGly: 1.729 ± 0.341
0.346ArgHis: 0.346 ± 0.203
3.689ArgIle: 3.689 ± 0.616
2.306ArgLys: 2.306 ± 0.645
4.035ArgLeu: 4.035 ± 0.702
0.922ArgMet: 0.922 ± 0.348
1.153ArgAsn: 1.153 ± 0.371
0.461ArgPro: 0.461 ± 0.319
1.038ArgGln: 1.038 ± 0.367
0.576ArgArg: 0.576 ± 0.232
1.499ArgSer: 1.499 ± 0.475
1.614ArgThr: 1.614 ± 0.531
1.614ArgVal: 1.614 ± 0.517
0.0ArgTrp: 0.0 ± 0.0
1.383ArgTyr: 1.383 ± 0.321
0.0ArgXaa: 0.0 ± 0.0
Ser
2.536SerAla: 2.536 ± 0.585
0.922SerCys: 0.922 ± 0.282
3.113SerAsp: 3.113 ± 0.686
5.764SerGlu: 5.764 ± 1.266
2.19SerPhe: 2.19 ± 0.421
2.767SerGly: 2.767 ± 0.577
0.576SerHis: 0.576 ± 0.389
6.11SerIle: 6.11 ± 0.753
3.689SerLys: 3.689 ± 0.591
6.687SerLeu: 6.687 ± 0.825
2.652SerMet: 2.652 ± 0.565
2.997SerAsn: 2.997 ± 0.696
3.343SerPro: 3.343 ± 0.914
1.845SerGln: 1.845 ± 0.484
1.499SerArg: 1.499 ± 0.459
4.842SerSer: 4.842 ± 0.719
2.882SerThr: 2.882 ± 0.561
2.536SerVal: 2.536 ± 0.559
0.692SerTrp: 0.692 ± 0.262
2.421SerTyr: 2.421 ± 0.456
0.0SerXaa: 0.0 ± 0.0
Thr
2.306ThrAla: 2.306 ± 0.506
0.692ThrCys: 0.692 ± 0.276
2.997ThrAsp: 2.997 ± 0.718
2.997ThrGlu: 2.997 ± 0.473
2.767ThrPhe: 2.767 ± 0.529
1.268ThrGly: 1.268 ± 0.352
0.807ThrHis: 0.807 ± 0.381
5.418ThrIle: 5.418 ± 0.793
2.767ThrLys: 2.767 ± 0.595
5.073ThrLeu: 5.073 ± 0.648
0.346ThrMet: 0.346 ± 0.204
2.306ThrAsn: 2.306 ± 0.449
2.882ThrPro: 2.882 ± 0.724
1.845ThrGln: 1.845 ± 0.63
1.038ThrArg: 1.038 ± 0.377
3.459ThrSer: 3.459 ± 0.598
3.228ThrThr: 3.228 ± 0.694
4.266ThrVal: 4.266 ± 0.728
0.461ThrTrp: 0.461 ± 0.261
3.459ThrTyr: 3.459 ± 0.682
0.0ThrXaa: 0.0 ± 0.0
Val
1.038ValAla: 1.038 ± 0.354
1.038ValCys: 1.038 ± 0.377
3.459ValAsp: 3.459 ± 0.605
4.266ValGlu: 4.266 ± 0.734
4.15ValPhe: 4.15 ± 0.874
2.882ValGly: 2.882 ± 0.715
0.807ValHis: 0.807 ± 0.35
6.687ValIle: 6.687 ± 0.851
6.802ValLys: 6.802 ± 0.942
7.955ValLeu: 7.955 ± 0.852
1.383ValMet: 1.383 ± 0.468
2.882ValAsn: 2.882 ± 0.605
2.882ValPro: 2.882 ± 0.491
2.075ValGln: 2.075 ± 0.624
1.614ValArg: 1.614 ± 0.426
4.381ValSer: 4.381 ± 0.671
4.381ValThr: 4.381 ± 0.833
4.381ValVal: 4.381 ± 0.945
0.0ValTrp: 0.0 ± 0.0
2.652ValTyr: 2.652 ± 0.62
0.0ValXaa: 0.0 ± 0.0
Trp
0.115TrpAla: 0.115 ± 0.102
0.231TrpCys: 0.231 ± 0.174
0.115TrpAsp: 0.115 ± 0.117
0.231TrpGlu: 0.231 ± 0.158
0.461TrpPhe: 0.461 ± 0.225
0.346TrpGly: 0.346 ± 0.242
0.231TrpHis: 0.231 ± 0.146
0.576TrpIle: 0.576 ± 0.349
0.461TrpLys: 0.461 ± 0.199
0.807TrpLeu: 0.807 ± 0.253
0.0TrpMet: 0.0 ± 0.0
0.461TrpAsn: 0.461 ± 0.221
0.0TrpPro: 0.0 ± 0.0
0.461TrpGln: 0.461 ± 0.196
0.231TrpArg: 0.231 ± 0.154
0.346TrpSer: 0.346 ± 0.178
0.346TrpThr: 0.346 ± 0.197
0.576TrpVal: 0.576 ± 0.25
0.115TrpTrp: 0.115 ± 0.106
1.038TrpTyr: 1.038 ± 0.301
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.574TyrAla: 3.574 ± 0.627
1.153TyrCys: 1.153 ± 0.428
3.459TyrAsp: 3.459 ± 0.712
3.343TyrGlu: 3.343 ± 0.651
3.689TyrPhe: 3.689 ± 0.763
2.19TyrGly: 2.19 ± 0.516
0.692TyrHis: 0.692 ± 0.236
3.343TyrIle: 3.343 ± 0.537
4.381TyrLys: 4.381 ± 0.635
6.571TyrLeu: 6.571 ± 0.821
0.807TyrMet: 0.807 ± 0.335
2.767TyrAsn: 2.767 ± 0.631
2.075TyrPro: 2.075 ± 0.571
1.499TyrGln: 1.499 ± 0.359
1.499TyrArg: 1.499 ± 0.349
3.343TyrSer: 3.343 ± 0.848
1.729TyrThr: 1.729 ± 0.447
4.842TyrVal: 4.842 ± 0.815
0.461TyrTrp: 0.461 ± 0.209
3.113TyrTyr: 3.113 ± 0.659
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 66 proteins (8675 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski