Amino acid dipepetide frequency for Coniothyrium minitans RNA virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.963AlaAla: 19.963 ± 5.66
1.248AlaCys: 1.248 ± 0.029
1.871AlaAsp: 1.871 ± 0.477
5.614AlaGlu: 5.614 ± 1.43
1.871AlaPhe: 1.871 ± 0.477
13.1AlaGly: 13.1 ± 4.202
3.743AlaHis: 3.743 ± 0.953
3.119AlaIle: 3.119 ± 1.371
3.119AlaLys: 3.119 ± 0.36
12.477AlaLeu: 12.477 ± 0.292
2.495AlaMet: 2.495 ± 0.807
4.991AlaAsn: 4.991 ± 1.848
8.734AlaPro: 8.734 ± 1.935
2.495AlaGln: 2.495 ± 0.924
8.734AlaArg: 8.734 ± 0.204
11.229AlaSer: 11.229 ± 0.262
3.743AlaThr: 3.743 ± 1.644
8.11AlaVal: 8.11 ± 1.488
3.119AlaTrp: 3.119 ± 1.226
3.119AlaTyr: 3.119 ± 0.36
0.0AlaXaa: 0.0 ± 0.0
Cys
0.624CysAla: 0.624 ± 0.447
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.248CysGly: 1.248 ± 0.029
0.0CysHis: 0.0 ± 0.0
0.624CysIle: 0.624 ± 0.447
0.0CysLys: 0.0 ± 0.0
1.248CysLeu: 1.248 ± 0.836
0.0CysMet: 0.0 ± 0.0
0.624CysAsn: 0.624 ± 0.418
0.624CysPro: 0.624 ± 0.418
0.0CysGln: 0.0 ± 0.0
0.624CysArg: 0.624 ± 0.418
0.0CysSer: 0.0 ± 0.0
0.624CysThr: 0.624 ± 0.447
2.495CysVal: 2.495 ± 0.807
0.0CysTrp: 0.0 ± 0.0
0.624CysTyr: 0.624 ± 0.418
0.0CysXaa: 0.0 ± 0.0
Asp
6.238AspAla: 6.238 ± 1.877
0.0AspCys: 0.0 ± 0.0
6.238AspAsp: 6.238 ± 0.72
3.119AspGlu: 3.119 ± 1.371
3.119AspPhe: 3.119 ± 1.226
1.248AspGly: 1.248 ± 0.029
1.248AspHis: 1.248 ± 0.029
1.871AspIle: 1.871 ± 0.389
0.624AspLys: 0.624 ± 0.418
4.367AspLeu: 4.367 ± 0.535
0.624AspMet: 0.624 ± 0.418
0.624AspAsn: 0.624 ± 0.447
2.495AspPro: 2.495 ± 0.924
3.119AspGln: 3.119 ± 0.506
2.495AspArg: 2.495 ± 0.924
4.991AspSer: 4.991 ± 0.749
3.743AspThr: 3.743 ± 0.778
5.614AspVal: 5.614 ± 0.564
0.624AspTrp: 0.624 ± 0.418
3.743AspTyr: 3.743 ± 1.644
0.0AspXaa: 0.0 ± 0.0
Glu
8.734GluAla: 8.734 ± 0.204
0.624GluCys: 0.624 ± 0.418
1.871GluAsp: 1.871 ± 1.255
1.871GluGlu: 1.871 ± 1.255
1.248GluPhe: 1.248 ± 0.836
3.119GluGly: 3.119 ± 2.237
2.495GluHis: 2.495 ± 0.058
1.248GluIle: 1.248 ± 0.029
1.248GluLys: 1.248 ± 0.836
3.119GluLeu: 3.119 ± 1.226
1.871GluMet: 1.871 ± 0.477
0.624GluAsn: 0.624 ± 0.447
1.248GluPro: 1.248 ± 0.895
0.0GluGln: 0.0 ± 0.0
3.743GluArg: 3.743 ± 0.087
0.624GluSer: 0.624 ± 0.418
3.119GluThr: 3.119 ± 1.226
3.119GluVal: 3.119 ± 0.36
0.624GluTrp: 0.624 ± 0.418
1.248GluTyr: 1.248 ± 0.836
0.0GluXaa: 0.0 ± 0.0
Phe
3.743PheAla: 3.743 ± 0.953
0.624PheCys: 0.624 ± 0.447
1.871PheAsp: 1.871 ± 0.389
1.871PheGlu: 1.871 ± 1.342
0.624PhePhe: 0.624 ± 0.418
2.495PheGly: 2.495 ± 0.058
0.0PheHis: 0.0 ± 0.0
0.624PheIle: 0.624 ± 0.447
1.248PheLys: 1.248 ± 0.029
3.743PheLeu: 3.743 ± 0.778
0.624PheMet: 0.624 ± 0.447
0.624PheAsn: 0.624 ± 0.418
2.495PhePro: 2.495 ± 0.807
0.0PheGln: 0.0 ± 0.0
1.248PheArg: 1.248 ± 0.029
4.367PheSer: 4.367 ± 1.401
0.624PheThr: 0.624 ± 0.447
0.0PheVal: 0.0 ± 0.0
0.624PheTrp: 0.624 ± 0.447
0.624PheTyr: 0.624 ± 0.447
0.0PheXaa: 0.0 ± 0.0
Gly
9.357GlyAla: 9.357 ± 1.517
0.624GlyCys: 0.624 ± 0.418
8.734GlyAsp: 8.734 ± 2.801
3.119GlyGlu: 3.119 ± 0.36
3.119GlyPhe: 3.119 ± 0.506
8.734GlyGly: 8.734 ± 3.667
2.495GlyHis: 2.495 ± 0.807
6.238GlyIle: 6.238 ± 0.146
2.495GlyLys: 2.495 ± 1.673
4.991GlyLeu: 4.991 ± 1.848
1.248GlyMet: 1.248 ± 0.029
1.248GlyAsn: 1.248 ± 0.895
6.862GlyPro: 6.862 ± 3.19
1.871GlyGln: 1.871 ± 0.477
6.862GlyArg: 6.862 ± 1.459
3.743GlySer: 3.743 ± 0.087
4.367GlyThr: 4.367 ± 2.266
6.238GlyVal: 6.238 ± 0.146
0.624GlyTrp: 0.624 ± 0.418
3.743GlyTyr: 3.743 ± 1.644
0.0GlyXaa: 0.0 ± 0.0
His
2.495HisAla: 2.495 ± 0.058
0.0HisCys: 0.0 ± 0.0
0.624HisAsp: 0.624 ± 0.447
1.248HisGlu: 1.248 ± 0.029
0.624HisPhe: 0.624 ± 0.447
3.743HisGly: 3.743 ± 0.953
1.248HisHis: 1.248 ± 0.029
0.0HisIle: 0.0 ± 0.0
0.624HisLys: 0.624 ± 0.447
2.495HisLeu: 2.495 ± 0.058
0.624HisMet: 0.624 ± 0.418
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.624HisGln: 0.624 ± 0.447
1.871HisArg: 1.871 ± 1.255
1.248HisSer: 1.248 ± 0.029
2.495HisThr: 2.495 ± 0.058
3.743HisVal: 3.743 ± 0.087
0.624HisTrp: 0.624 ± 0.418
0.624HisTyr: 0.624 ± 0.418
0.0HisXaa: 0.0 ± 0.0
Ile
3.743IleAla: 3.743 ± 1.819
0.624IleCys: 0.624 ± 0.418
2.495IleAsp: 2.495 ± 0.058
2.495IleGlu: 2.495 ± 0.058
1.871IlePhe: 1.871 ± 0.477
3.743IleGly: 3.743 ± 0.953
1.248IleHis: 1.248 ± 0.895
0.0IleIle: 0.0 ± 0.0
0.624IleLys: 0.624 ± 0.418
2.495IleLeu: 2.495 ± 0.807
0.0IleMet: 0.0 ± 0.0
3.743IleAsn: 3.743 ± 0.087
3.119IlePro: 3.119 ± 2.237
0.0IleGln: 0.0 ± 0.0
1.871IleArg: 1.871 ± 1.255
3.743IleSer: 3.743 ± 0.087
2.495IleThr: 2.495 ± 0.058
3.119IleVal: 3.119 ± 0.36
0.0IleTrp: 0.0 ± 0.0
0.624IleTyr: 0.624 ± 0.418
0.0IleXaa: 0.0 ± 0.0
Lys
1.871LysAla: 1.871 ± 0.389
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
0.0LysGlu: 0.0 ± 0.0
0.624LysPhe: 0.624 ± 0.447
2.495LysGly: 2.495 ± 0.807
1.248LysHis: 1.248 ± 0.029
0.0LysIle: 0.0 ± 0.0
1.871LysLys: 1.871 ± 1.255
3.119LysLeu: 3.119 ± 1.226
1.248LysMet: 1.248 ± 0.029
1.871LysAsn: 1.871 ± 0.389
0.624LysPro: 0.624 ± 0.418
0.624LysGln: 0.624 ± 0.418
1.871LysArg: 1.871 ± 1.255
0.624LysSer: 0.624 ± 0.418
3.743LysThr: 3.743 ± 0.778
1.248LysVal: 1.248 ± 0.836
0.0LysTrp: 0.0 ± 0.0
1.248LysTyr: 1.248 ± 0.029
0.0LysXaa: 0.0 ± 0.0
Leu
11.229LeuAla: 11.229 ± 0.603
1.248LeuCys: 1.248 ± 0.029
5.614LeuAsp: 5.614 ± 1.167
4.991LeuGlu: 4.991 ± 2.48
1.248LeuPhe: 1.248 ± 0.029
6.238LeuGly: 6.238 ± 0.72
2.495LeuHis: 2.495 ± 1.673
1.871LeuIle: 1.871 ± 0.477
3.119LeuLys: 3.119 ± 0.36
7.486LeuLeu: 7.486 ± 3.288
1.871LeuMet: 1.871 ± 1.255
1.248LeuAsn: 1.248 ± 0.836
4.367LeuPro: 4.367 ± 0.535
2.495LeuGln: 2.495 ± 0.807
9.981LeuArg: 9.981 ± 1.099
4.367LeuSer: 4.367 ± 1.196
6.862LeuThr: 6.862 ± 1.138
4.367LeuVal: 4.367 ± 0.331
1.248LeuTrp: 1.248 ± 0.029
2.495LeuTyr: 2.495 ± 0.058
0.0LeuXaa: 0.0 ± 0.0
Met
3.119MetAla: 3.119 ± 0.36
0.0MetCys: 0.0 ± 0.0
1.248MetAsp: 1.248 ± 0.895
1.871MetGlu: 1.871 ± 0.389
0.0MetPhe: 0.0 ± 0.0
0.624MetGly: 0.624 ± 0.447
0.0MetHis: 0.0 ± 0.0
2.495MetIle: 2.495 ± 0.058
0.0MetLys: 0.0 ± 0.0
0.624MetLeu: 0.624 ± 0.418
0.624MetMet: 0.624 ± 0.418
0.624MetAsn: 0.624 ± 0.418
0.624MetPro: 0.624 ± 0.418
0.624MetGln: 0.624 ± 0.418
1.871MetArg: 1.871 ± 0.477
1.871MetSer: 1.871 ± 1.255
0.624MetThr: 0.624 ± 0.418
2.495MetVal: 2.495 ± 1.673
0.624MetTrp: 0.624 ± 0.447
1.248MetTyr: 1.248 ± 0.029
0.0MetXaa: 0.0 ± 0.0
Asn
1.248AsnAla: 1.248 ± 0.895
0.0AsnCys: 0.0 ± 0.0
1.248AsnAsp: 1.248 ± 0.029
1.871AsnGlu: 1.871 ± 0.389
1.871AsnPhe: 1.871 ± 1.342
3.119AsnGly: 3.119 ± 0.36
0.0AsnHis: 0.0 ± 0.0
1.871AsnIle: 1.871 ± 0.477
0.624AsnLys: 0.624 ± 0.418
1.248AsnLeu: 1.248 ± 0.029
0.624AsnMet: 0.624 ± 0.447
0.624AsnAsn: 0.624 ± 0.447
3.743AsnPro: 3.743 ± 0.778
1.248AsnGln: 1.248 ± 0.895
1.248AsnArg: 1.248 ± 0.836
3.119AsnSer: 3.119 ± 0.36
1.871AsnThr: 1.871 ± 0.477
3.119AsnVal: 3.119 ± 0.36
0.624AsnTrp: 0.624 ± 0.418
1.248AsnTyr: 1.248 ± 0.029
0.0AsnXaa: 0.0 ± 0.0
Pro
6.862ProAla: 6.862 ± 2.324
1.248ProCys: 1.248 ± 0.029
2.495ProAsp: 2.495 ± 0.807
0.624ProGlu: 0.624 ± 0.418
0.624ProPhe: 0.624 ± 0.447
4.991ProGly: 4.991 ± 1.848
1.871ProHis: 1.871 ± 0.477
1.871ProIle: 1.871 ± 0.477
1.871ProLys: 1.871 ± 0.389
6.862ProLeu: 6.862 ± 0.272
0.0ProMet: 0.0 ± 0.0
1.248ProAsn: 1.248 ± 0.029
9.357ProPro: 9.357 ± 5.845
1.871ProGln: 1.871 ± 1.342
3.119ProArg: 3.119 ± 0.36
2.495ProSer: 2.495 ± 0.058
8.11ProThr: 8.11 ± 3.219
4.991ProVal: 4.991 ± 0.982
0.0ProTrp: 0.0 ± 0.0
2.495ProTyr: 2.495 ± 0.058
0.0ProXaa: 0.0 ± 0.0
Gln
4.367GlnAla: 4.367 ± 1.401
0.0GlnCys: 0.0 ± 0.0
1.871GlnAsp: 1.871 ± 0.477
0.624GlnGlu: 0.624 ± 0.418
0.624GlnPhe: 0.624 ± 0.447
1.871GlnGly: 1.871 ± 1.342
0.0GlnHis: 0.0 ± 0.0
1.871GlnIle: 1.871 ± 0.389
0.0GlnLys: 0.0 ± 0.0
0.624GlnLeu: 0.624 ± 0.418
0.0GlnMet: 0.0 ± 0.0
0.624GlnAsn: 0.624 ± 0.418
0.624GlnPro: 0.624 ± 0.447
0.0GlnGln: 0.0 ± 0.0
1.871GlnArg: 1.871 ± 1.255
2.495GlnSer: 2.495 ± 0.058
1.248GlnThr: 1.248 ± 0.895
2.495GlnVal: 2.495 ± 0.058
1.248GlnTrp: 1.248 ± 0.029
1.871GlnTyr: 1.871 ± 0.389
0.0GlnXaa: 0.0 ± 0.0
Arg
9.981ArgAla: 9.981 ± 0.233
0.0ArgCys: 0.0 ± 0.0
4.367ArgAsp: 4.367 ± 2.062
3.743ArgGlu: 3.743 ± 0.778
3.119ArgPhe: 3.119 ± 0.506
6.238ArgGly: 6.238 ± 1.877
3.119ArgHis: 3.119 ± 0.506
2.495ArgIle: 2.495 ± 0.924
1.248ArgLys: 1.248 ± 0.029
4.367ArgLeu: 4.367 ± 0.331
3.119ArgMet: 3.119 ± 2.091
1.248ArgAsn: 1.248 ± 0.029
3.119ArgPro: 3.119 ± 2.091
1.248ArgGln: 1.248 ± 0.029
6.238ArgArg: 6.238 ± 0.72
5.614ArgSer: 5.614 ± 2.033
4.367ArgThr: 4.367 ± 0.331
6.862ArgVal: 6.862 ± 1.138
1.248ArgTrp: 1.248 ± 0.836
3.119ArgTyr: 3.119 ± 0.36
0.0ArgXaa: 0.0 ± 0.0
Ser
6.238SerAla: 6.238 ± 0.72
0.0SerCys: 0.0 ± 0.0
3.743SerAsp: 3.743 ± 0.953
1.871SerGlu: 1.871 ± 0.389
1.871SerPhe: 1.871 ± 1.255
6.862SerGly: 6.862 ± 1.138
1.248SerHis: 1.248 ± 0.836
1.248SerIle: 1.248 ± 0.029
1.248SerLys: 1.248 ± 0.836
6.862SerLeu: 6.862 ± 0.272
1.248SerMet: 1.248 ± 0.836
3.119SerAsn: 3.119 ± 1.371
3.743SerPro: 3.743 ± 1.819
2.495SerGln: 2.495 ± 0.058
3.743SerArg: 3.743 ± 1.644
6.238SerSer: 6.238 ± 0.146
4.367SerThr: 4.367 ± 0.535
5.614SerVal: 5.614 ± 0.564
1.871SerTrp: 1.871 ± 0.389
6.238SerTyr: 6.238 ± 1.585
0.0SerXaa: 0.0 ± 0.0
Thr
6.862ThrAla: 6.862 ± 2.324
1.248ThrCys: 1.248 ± 0.836
3.743ThrAsp: 3.743 ± 1.819
0.624ThrGlu: 0.624 ± 0.418
1.248ThrPhe: 1.248 ± 0.895
4.367ThrGly: 4.367 ± 0.331
1.248ThrHis: 1.248 ± 0.029
3.743ThrIle: 3.743 ± 0.087
1.248ThrLys: 1.248 ± 0.029
3.743ThrLeu: 3.743 ± 1.644
1.871ThrMet: 1.871 ± 0.477
3.119ThrAsn: 3.119 ± 0.36
3.743ThrPro: 3.743 ± 0.087
1.871ThrGln: 1.871 ± 0.477
5.614ThrArg: 5.614 ± 2.033
4.991ThrSer: 4.991 ± 0.982
3.119ThrThr: 3.119 ± 2.091
8.11ThrVal: 8.11 ± 1.488
1.248ThrTrp: 1.248 ± 0.895
1.871ThrTyr: 1.871 ± 1.255
0.0ThrXaa: 0.0 ± 0.0
Val
11.229ValAla: 11.229 ± 1.128
1.248ValCys: 1.248 ± 0.029
3.119ValAsp: 3.119 ± 0.506
4.367ValGlu: 4.367 ± 2.062
3.743ValPhe: 3.743 ± 0.953
8.11ValGly: 8.11 ± 1.109
1.248ValHis: 1.248 ± 0.895
3.743ValIle: 3.743 ± 0.953
0.624ValLys: 0.624 ± 0.418
6.862ValLeu: 6.862 ± 2.869
1.871ValMet: 1.871 ± 0.044
3.119ValAsn: 3.119 ± 0.36
4.991ValPro: 4.991 ± 1.848
1.248ValGln: 1.248 ± 0.836
6.238ValArg: 6.238 ± 0.72
6.862ValSer: 6.862 ± 0.272
6.238ValThr: 6.238 ± 1.011
5.614ValVal: 5.614 ± 1.43
0.0ValTrp: 0.0 ± 0.0
1.871ValTyr: 1.871 ± 0.389
0.0ValXaa: 0.0 ± 0.0
Trp
1.871TrpAla: 1.871 ± 1.255
0.0TrpCys: 0.0 ± 0.0
3.119TrpAsp: 3.119 ± 0.36
0.624TrpGlu: 0.624 ± 0.447
0.0TrpPhe: 0.0 ± 0.0
0.624TrpGly: 0.624 ± 0.418
0.0TrpHis: 0.0 ± 0.0
0.624TrpIle: 0.624 ± 0.418
0.0TrpLys: 0.0 ± 0.0
1.248TrpLeu: 1.248 ± 0.029
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.624TrpGln: 0.624 ± 0.418
2.495TrpArg: 2.495 ± 0.807
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
3.119TrpVal: 3.119 ± 0.506
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.119TyrAla: 3.119 ± 0.36
0.624TyrCys: 0.624 ± 0.418
1.871TyrAsp: 1.871 ± 1.255
1.248TyrGlu: 1.248 ± 0.029
0.624TyrPhe: 0.624 ± 0.447
3.743TyrGly: 3.743 ± 0.953
0.0TyrHis: 0.0 ± 0.0
2.495TyrIle: 2.495 ± 1.673
2.495TyrLys: 2.495 ± 0.807
6.862TyrLeu: 6.862 ± 2.004
0.624TyrMet: 0.624 ± 0.447
1.248TyrAsn: 1.248 ± 0.836
2.495TyrPro: 2.495 ± 0.058
1.871TyrGln: 1.871 ± 0.389
3.119TyrArg: 3.119 ± 0.36
1.248TyrSer: 1.248 ± 0.836
1.871TyrThr: 1.871 ± 0.389
2.495TyrVal: 2.495 ± 1.673
0.0TyrTrp: 0.0 ± 0.0
0.624TyrTyr: 0.624 ± 0.418
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1604 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski