Amino acid dipepetide frequency for Cowpea polerovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.802AlaAla: 4.802 ± 1.432
0.64AlaCys: 0.64 ± 0.445
3.841AlaAsp: 3.841 ± 0.715
3.201AlaGlu: 3.201 ± 0.903
1.921AlaPhe: 1.921 ± 0.972
4.481AlaGly: 4.481 ± 0.916
0.96AlaHis: 0.96 ± 0.608
3.201AlaIle: 3.201 ± 0.719
3.201AlaLys: 3.201 ± 0.776
4.802AlaLeu: 4.802 ± 0.923
0.64AlaMet: 0.64 ± 0.254
2.241AlaAsn: 2.241 ± 0.643
5.122AlaPro: 5.122 ± 0.898
1.601AlaGln: 1.601 ± 0.818
5.442AlaArg: 5.442 ± 2.238
6.402AlaSer: 6.402 ± 1.554
4.161AlaThr: 4.161 ± 0.767
5.762AlaVal: 5.762 ± 0.9
2.241AlaTrp: 2.241 ± 0.45
2.881AlaTyr: 2.881 ± 0.516
0.0AlaXaa: 0.0 ± 0.0
Cys
1.921CysAla: 1.921 ± 0.725
0.96CysCys: 0.96 ± 0.362
0.64CysAsp: 0.64 ± 0.254
1.601CysGlu: 1.601 ± 0.422
0.96CysPhe: 0.96 ± 0.567
1.28CysGly: 1.28 ± 0.611
0.0CysHis: 0.0 ± 0.0
0.64CysIle: 0.64 ± 0.395
1.921CysLys: 1.921 ± 0.552
2.561CysLeu: 2.561 ± 0.671
0.0CysMet: 0.0 ± 0.0
1.601CysAsn: 1.601 ± 0.406
0.32CysPro: 0.32 ± 0.217
1.601CysGln: 1.601 ± 0.457
1.28CysArg: 1.28 ± 0.886
1.28CysSer: 1.28 ± 0.545
0.0CysThr: 0.0 ± 0.0
1.28CysVal: 1.28 ± 0.378
0.64CysTrp: 0.64 ± 0.246
0.64CysTyr: 0.64 ± 0.246
0.0CysXaa: 0.0 ± 0.0
Asp
3.841AspAla: 3.841 ± 0.594
1.601AspCys: 1.601 ± 0.58
2.881AspAsp: 2.881 ± 1.29
2.881AspGlu: 2.881 ± 0.637
1.921AspPhe: 1.921 ± 0.464
1.601AspGly: 1.601 ± 0.593
0.96AspHis: 0.96 ± 0.898
0.96AspIle: 0.96 ± 0.365
2.241AspLys: 2.241 ± 0.539
2.881AspLeu: 2.881 ± 0.878
0.64AspMet: 0.64 ± 0.246
1.28AspAsn: 1.28 ± 0.743
3.201AspPro: 3.201 ± 0.819
2.881AspGln: 2.881 ± 0.88
2.561AspArg: 2.561 ± 0.786
2.881AspSer: 2.881 ± 1.084
1.921AspThr: 1.921 ± 0.387
0.64AspVal: 0.64 ± 0.511
1.921AspTrp: 1.921 ± 0.501
1.28AspTyr: 1.28 ± 0.886
0.0AspXaa: 0.0 ± 0.0
Glu
4.481GluAla: 4.481 ± 0.991
0.64GluCys: 0.64 ± 0.246
4.802GluAsp: 4.802 ± 0.216
5.122GluGlu: 5.122 ± 1.581
4.161GluPhe: 4.161 ± 1.604
3.521GluGly: 3.521 ± 0.964
0.32GluHis: 0.32 ± 0.289
2.881GluIle: 2.881 ± 0.519
3.201GluLys: 3.201 ± 0.979
5.442GluLeu: 5.442 ± 1.304
0.64GluMet: 0.64 ± 0.254
2.241GluAsn: 2.241 ± 0.6
1.601GluPro: 1.601 ± 0.471
2.241GluGln: 2.241 ± 0.641
2.241GluArg: 2.241 ± 0.757
2.561GluSer: 2.561 ± 0.604
2.881GluThr: 2.881 ± 0.611
3.201GluVal: 3.201 ± 0.801
3.201GluTrp: 3.201 ± 0.72
2.241GluTyr: 2.241 ± 0.993
0.0GluXaa: 0.0 ± 0.0
Phe
1.28PheAla: 1.28 ± 0.544
3.201PheCys: 3.201 ± 0.826
2.241PheAsp: 2.241 ± 0.665
1.921PheGlu: 1.921 ± 0.387
2.881PhePhe: 2.881 ± 1.052
4.161PheGly: 4.161 ± 1.145
1.921PheHis: 1.921 ± 0.9
2.241PheIle: 2.241 ± 0.586
3.201PheLys: 3.201 ± 0.303
5.122PheLeu: 5.122 ± 1.985
0.0PheMet: 0.0 ± 0.0
0.32PheAsn: 0.32 ± 0.217
0.32PhePro: 0.32 ± 0.217
2.561PheGln: 2.561 ± 0.52
4.161PheArg: 4.161 ± 1.152
3.201PheSer: 3.201 ± 0.288
4.481PheThr: 4.481 ± 0.474
3.841PheVal: 3.841 ± 0.72
1.28PheTrp: 1.28 ± 0.378
0.96PheTyr: 0.96 ± 0.411
0.0PheXaa: 0.0 ± 0.0
Gly
3.841GlyAla: 3.841 ± 0.305
2.561GlyCys: 2.561 ± 0.711
1.921GlyAsp: 1.921 ± 0.678
5.442GlyGlu: 5.442 ± 0.876
2.561GlyPhe: 2.561 ± 0.897
6.082GlyGly: 6.082 ± 1.319
0.64GlyHis: 0.64 ± 0.454
2.561GlyIle: 2.561 ± 0.718
7.042GlyLys: 7.042 ± 1.905
7.362GlyLeu: 7.362 ± 0.906
0.32GlyMet: 0.32 ± 0.227
4.161GlyAsn: 4.161 ± 0.998
4.802GlyPro: 4.802 ± 1.061
2.881GlyGln: 2.881 ± 0.481
4.161GlyArg: 4.161 ± 1.413
5.762GlySer: 5.762 ± 1.431
3.841GlyThr: 3.841 ± 0.917
6.402GlyVal: 6.402 ± 0.925
0.32GlyTrp: 0.32 ± 0.217
3.841GlyTyr: 3.841 ± 0.753
0.0GlyXaa: 0.0 ± 0.0
His
1.601HisAla: 1.601 ± 0.912
1.28HisCys: 1.28 ± 0.48
1.28HisAsp: 1.28 ± 0.513
1.28HisGlu: 1.28 ± 1.003
0.64HisPhe: 0.64 ± 0.246
1.28HisGly: 1.28 ± 0.491
0.96HisHis: 0.96 ± 0.411
1.28HisIle: 1.28 ± 0.402
0.96HisLys: 0.96 ± 0.362
0.64HisLeu: 0.64 ± 0.373
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.28HisPro: 1.28 ± 0.611
0.64HisGln: 0.64 ± 0.445
0.96HisArg: 0.96 ± 0.705
0.32HisSer: 0.32 ± 0.479
0.96HisThr: 0.96 ± 0.233
2.241HisVal: 2.241 ± 0.5
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.881IleAla: 2.881 ± 0.524
0.0IleCys: 0.0 ± 0.0
1.601IleAsp: 1.601 ± 0.593
2.561IleGlu: 2.561 ± 0.397
4.161IlePhe: 4.161 ± 1.333
0.96IleGly: 0.96 ± 0.629
0.0IleHis: 0.0 ± 0.0
0.96IleIle: 0.96 ± 0.233
1.921IleLys: 1.921 ± 0.552
4.481IleLeu: 4.481 ± 1.263
1.601IleMet: 1.601 ± 0.58
3.521IleAsn: 3.521 ± 0.94
3.201IlePro: 3.201 ± 0.883
1.921IleGln: 1.921 ± 0.545
1.28IleArg: 1.28 ± 0.661
3.201IleSer: 3.201 ± 0.561
3.201IleThr: 3.201 ± 0.813
1.601IleVal: 1.601 ± 0.427
0.0IleTrp: 0.0 ± 0.0
0.64IleTyr: 0.64 ± 0.411
0.0IleXaa: 0.0 ± 0.0
Lys
3.521LysAla: 3.521 ± 0.76
0.64LysCys: 0.64 ± 0.246
1.601LysAsp: 1.601 ± 0.469
3.201LysGlu: 3.201 ± 0.979
2.561LysPhe: 2.561 ± 1.502
6.082LysGly: 6.082 ± 1.295
1.921LysHis: 1.921 ± 0.725
3.201LysIle: 3.201 ± 0.496
1.28LysLys: 1.28 ± 0.46
3.201LysLeu: 3.201 ± 0.606
1.28LysMet: 1.28 ± 0.452
0.64LysAsn: 0.64 ± 0.52
6.722LysPro: 6.722 ± 1.36
3.521LysGln: 3.521 ± 1.178
4.802LysArg: 4.802 ± 0.927
3.201LysSer: 3.201 ± 0.583
4.161LysThr: 4.161 ± 0.622
1.921LysVal: 1.921 ± 0.488
1.28LysTrp: 1.28 ± 0.302
0.64LysTyr: 0.64 ± 0.383
0.32LysXaa: 0.32 ± 0.227
Leu
5.762LeuAla: 5.762 ± 1.709
1.601LeuCys: 1.601 ± 0.538
3.521LeuAsp: 3.521 ± 0.602
5.122LeuGlu: 5.122 ± 1.179
3.841LeuPhe: 3.841 ± 0.906
6.402LeuGly: 6.402 ± 1.255
0.96LeuHis: 0.96 ± 0.362
2.881LeuIle: 2.881 ± 0.88
4.481LeuLys: 4.481 ± 0.719
4.161LeuLeu: 4.161 ± 1.571
1.921LeuMet: 1.921 ± 0.384
1.921LeuAsn: 1.921 ± 0.746
4.161LeuPro: 4.161 ± 0.545
4.161LeuGln: 4.161 ± 0.763
5.442LeuArg: 5.442 ± 1.88
10.243LeuSer: 10.243 ± 1.221
3.841LeuThr: 3.841 ± 0.616
6.722LeuVal: 6.722 ± 1.652
2.561LeuTrp: 2.561 ± 0.559
4.481LeuTyr: 4.481 ± 0.369
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.64MetCys: 0.64 ± 0.254
0.32MetAsp: 0.32 ± 0.34
1.601MetGlu: 1.601 ± 0.661
0.0MetPhe: 0.0 ± 0.0
0.32MetGly: 0.32 ± 0.217
0.0MetHis: 0.0 ± 0.0
0.64MetIle: 0.64 ± 0.246
0.0MetLys: 0.0 ± 0.0
2.561MetLeu: 2.561 ± 0.604
0.0MetMet: 0.0 ± 0.0
2.561MetAsn: 2.561 ± 0.388
0.64MetPro: 0.64 ± 0.246
0.0MetGln: 0.0 ± 0.0
1.28MetArg: 1.28 ± 0.498
1.28MetSer: 1.28 ± 0.458
0.32MetThr: 0.32 ± 0.289
1.601MetVal: 1.601 ± 0.406
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.241AsnAla: 2.241 ± 0.587
0.32AsnCys: 0.32 ± 0.227
1.601AsnAsp: 1.601 ± 0.624
1.28AsnGlu: 1.28 ± 0.607
2.881AsnPhe: 2.881 ± 0.759
7.362AsnGly: 7.362 ± 2.232
0.32AsnHis: 0.32 ± 0.364
2.561AsnIle: 2.561 ± 0.595
2.881AsnLys: 2.881 ± 0.706
2.561AsnLeu: 2.561 ± 0.848
0.96AsnMet: 0.96 ± 0.485
2.561AsnAsn: 2.561 ± 0.753
1.28AsnPro: 1.28 ± 0.48
0.96AsnGln: 0.96 ± 0.233
2.881AsnArg: 2.881 ± 0.72
6.082AsnSer: 6.082 ± 1.05
0.32AsnThr: 0.32 ± 0.217
0.96AsnVal: 0.96 ± 0.362
1.601AsnTrp: 1.601 ± 0.53
2.241AsnTyr: 2.241 ± 0.627
0.0AsnXaa: 0.0 ± 0.0
Pro
2.241ProAla: 2.241 ± 0.643
0.32ProCys: 0.32 ± 0.227
2.561ProAsp: 2.561 ± 1.021
3.521ProGlu: 3.521 ± 0.999
0.64ProPhe: 0.64 ± 0.511
5.122ProGly: 5.122 ± 0.623
1.28ProHis: 1.28 ± 0.359
1.601ProIle: 1.601 ± 0.676
5.442ProLys: 5.442 ± 0.908
4.161ProLeu: 4.161 ± 0.985
0.32ProMet: 0.32 ± 0.333
1.601ProAsn: 1.601 ± 0.501
5.762ProPro: 5.762 ± 1.684
3.521ProGln: 3.521 ± 1.476
3.841ProArg: 3.841 ± 1.29
4.802ProSer: 4.802 ± 0.695
4.161ProThr: 4.161 ± 0.768
5.762ProVal: 5.762 ± 1.542
0.0ProTrp: 0.0 ± 0.0
0.96ProTyr: 0.96 ± 0.377
0.0ProXaa: 0.0 ± 0.0
Gln
3.521GlnAla: 3.521 ± 0.906
0.64GlnCys: 0.64 ± 0.246
1.921GlnAsp: 1.921 ± 0.68
3.201GlnGlu: 3.201 ± 0.675
3.521GlnPhe: 3.521 ± 0.857
1.921GlnGly: 1.921 ± 0.752
0.0GlnHis: 0.0 ± 0.0
1.28GlnIle: 1.28 ± 0.525
1.601GlnLys: 1.601 ± 0.539
3.201GlnLeu: 3.201 ± 0.979
0.0GlnMet: 0.0 ± 0.0
2.881GlnAsn: 2.881 ± 0.688
1.921GlnPro: 1.921 ± 0.397
1.28GlnGln: 1.28 ± 0.611
4.161GlnArg: 4.161 ± 1.433
3.521GlnSer: 3.521 ± 0.868
2.881GlnThr: 2.881 ± 1.013
1.601GlnVal: 1.601 ± 0.746
0.96GlnTrp: 0.96 ± 0.491
1.28GlnTyr: 1.28 ± 0.639
0.0GlnXaa: 0.0 ± 0.0
Arg
4.481ArgAla: 4.481 ± 1.2
1.28ArgCys: 1.28 ± 1.003
1.921ArgAsp: 1.921 ± 0.382
2.241ArgGlu: 2.241 ± 0.463
2.561ArgPhe: 2.561 ± 1.079
5.762ArgGly: 5.762 ± 1.261
1.28ArgHis: 1.28 ± 0.89
3.201ArgIle: 3.201 ± 1.126
3.201ArgLys: 3.201 ± 1.157
7.042ArgLeu: 7.042 ± 1.452
0.96ArgMet: 0.96 ± 0.306
4.161ArgAsn: 4.161 ± 0.563
1.601ArgPro: 1.601 ± 1.045
2.881ArgGln: 2.881 ± 1.14
11.204ArgArg: 11.204 ± 3.406
5.442ArgSer: 5.442 ± 1.271
4.161ArgThr: 4.161 ± 0.947
4.161ArgVal: 4.161 ± 1.029
1.601ArgTrp: 1.601 ± 0.58
1.28ArgTyr: 1.28 ± 0.402
0.0ArgXaa: 0.0 ± 0.0
Ser
6.402SerAla: 6.402 ± 1.2
1.28SerCys: 1.28 ± 0.796
3.841SerAsp: 3.841 ± 0.785
2.241SerGlu: 2.241 ± 0.572
3.521SerPhe: 3.521 ± 0.886
9.603SerGly: 9.603 ± 1.851
1.28SerHis: 1.28 ± 0.402
5.762SerIle: 5.762 ± 1.55
4.161SerLys: 4.161 ± 0.707
8.323SerLeu: 8.323 ± 1.438
0.32SerMet: 0.32 ± 0.209
3.201SerAsn: 3.201 ± 0.437
4.161SerPro: 4.161 ± 0.512
2.881SerGln: 2.881 ± 0.752
5.442SerArg: 5.442 ± 1.107
12.484SerSer: 12.484 ± 1.942
5.442SerThr: 5.442 ± 0.872
8.323SerVal: 8.323 ± 0.673
0.32SerTrp: 0.32 ± 0.364
2.881SerTyr: 2.881 ± 0.662
0.0SerXaa: 0.0 ± 0.0
Thr
4.802ThrAla: 4.802 ± 0.733
0.96ThrCys: 0.96 ± 0.362
0.96ThrAsp: 0.96 ± 0.415
3.521ThrGlu: 3.521 ± 0.64
3.201ThrPhe: 3.201 ± 1.001
2.881ThrGly: 2.881 ± 0.891
0.64ThrHis: 0.64 ± 0.373
1.601ThrIle: 1.601 ± 0.422
0.96ThrLys: 0.96 ± 0.43
5.122ThrLeu: 5.122 ± 1.403
2.241ThrMet: 2.241 ± 0.709
1.921ThrAsn: 1.921 ± 0.522
5.762ThrPro: 5.762 ± 0.894
1.28ThrGln: 1.28 ± 0.302
2.881ThrArg: 2.881 ± 0.416
5.442ThrSer: 5.442 ± 0.681
1.601ThrThr: 1.601 ± 0.904
3.201ThrVal: 3.201 ± 0.404
1.921ThrTrp: 1.921 ± 0.482
0.96ThrTyr: 0.96 ± 0.411
0.0ThrXaa: 0.0 ± 0.0
Val
6.402ValAla: 6.402 ± 1.206
0.64ValCys: 0.64 ± 0.445
1.28ValAsp: 1.28 ± 0.508
3.201ValGlu: 3.201 ± 0.717
4.481ValPhe: 4.481 ± 0.619
2.881ValGly: 2.881 ± 0.695
0.64ValHis: 0.64 ± 0.246
1.28ValIle: 1.28 ± 0.611
3.841ValLys: 3.841 ± 0.743
8.323ValLeu: 8.323 ± 1.593
0.32ValMet: 0.32 ± 0.364
2.881ValAsn: 2.881 ± 0.431
5.122ValPro: 5.122 ± 1.27
3.841ValGln: 3.841 ± 1.03
4.481ValArg: 4.481 ± 0.739
7.682ValSer: 7.682 ± 1.003
2.241ValThr: 2.241 ± 0.405
5.122ValVal: 5.122 ± 1.384
1.28ValTrp: 1.28 ± 0.491
1.28ValTyr: 1.28 ± 0.378
0.0ValXaa: 0.0 ± 0.0
Trp
0.64TrpAla: 0.64 ± 0.246
0.96TrpCys: 0.96 ± 0.362
0.32TrpAsp: 0.32 ± 0.217
1.921TrpGlu: 1.921 ± 0.488
1.28TrpPhe: 1.28 ± 0.491
3.521TrpGly: 3.521 ± 0.784
1.28TrpHis: 1.28 ± 0.359
0.32TrpIle: 0.32 ± 0.364
0.96TrpLys: 0.96 ± 0.415
1.601TrpLeu: 1.601 ± 0.538
0.96TrpMet: 0.96 ± 0.362
0.96TrpAsn: 0.96 ± 0.49
0.32TrpPro: 0.32 ± 0.217
0.0TrpGln: 0.0 ± 0.0
0.64TrpArg: 0.64 ± 0.434
2.881TrpSer: 2.881 ± 0.954
0.32TrpThr: 0.32 ± 0.227
0.96TrpVal: 0.96 ± 0.528
0.0TrpTrp: 0.0 ± 0.0
1.28TrpTyr: 1.28 ± 0.302
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.881TyrAla: 2.881 ± 0.717
0.96TyrCys: 0.96 ± 0.664
1.921TyrAsp: 1.921 ± 0.466
2.561TyrGlu: 2.561 ± 0.594
1.601TyrPhe: 1.601 ± 1.101
1.28TyrGly: 1.28 ± 0.378
2.241TyrHis: 2.241 ± 0.515
0.64TyrIle: 0.64 ± 0.454
3.201TyrLys: 3.201 ± 0.804
0.96TyrLeu: 0.96 ± 0.608
0.32TyrMet: 0.32 ± 0.227
3.201TyrAsn: 3.201 ± 0.738
0.32TyrPro: 0.32 ± 0.479
0.64TyrGln: 0.64 ± 0.246
1.28TyrArg: 1.28 ± 0.545
3.201TyrSer: 3.201 ± 0.328
0.96TyrThr: 0.96 ± 0.629
1.601TyrVal: 1.601 ± 0.471
0.0TyrTrp: 0.0 ± 0.0
0.64TyrTyr: 0.64 ± 0.246
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.32XaaVal: 0.32 ± 0.227
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3125 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski