Amino acid dipepetide frequency for Spinach latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.282AlaAla: 6.282 ± 1.787
0.393AlaCys: 0.393 ± 0.604
4.319AlaAsp: 4.319 ± 1.648
1.963AlaGlu: 1.963 ± 1.002
1.963AlaPhe: 1.963 ± 1.584
5.104AlaGly: 5.104 ± 1.092
1.963AlaHis: 1.963 ± 0.777
3.534AlaIle: 3.534 ± 1.482
3.534AlaLys: 3.534 ± 0.688
5.889AlaLeu: 5.889 ± 0.876
1.963AlaMet: 1.963 ± 0.711
2.748AlaAsn: 2.748 ± 0.334
3.926AlaPro: 3.926 ± 2.414
1.178AlaGln: 1.178 ± 0.631
3.926AlaArg: 3.926 ± 1.651
5.104AlaSer: 5.104 ± 1.627
3.926AlaThr: 3.926 ± 1.789
4.711AlaVal: 4.711 ± 0.721
0.393AlaTrp: 0.393 ± 0.278
3.534AlaTyr: 3.534 ± 0.879
0.0AlaXaa: 0.0 ± 0.0
Cys
1.963CysAla: 1.963 ± 0.604
0.785CysCys: 0.785 ± 0.545
2.356CysAsp: 2.356 ± 0.635
1.57CysGlu: 1.57 ± 0.572
2.356CysPhe: 2.356 ± 0.453
0.785CysGly: 0.785 ± 0.31
0.0CysHis: 0.0 ± 0.0
0.785CysIle: 0.785 ± 0.556
0.785CysLys: 0.785 ± 0.84
2.748CysLeu: 2.748 ± 1.041
0.0CysMet: 0.0 ± 0.0
1.178CysAsn: 1.178 ± 0.411
0.785CysPro: 0.785 ± 0.556
0.393CysGln: 0.393 ± 0.321
0.785CysArg: 0.785 ± 0.545
0.785CysSer: 0.785 ± 0.31
0.393CysThr: 0.393 ± 0.278
0.785CysVal: 0.785 ± 0.511
1.178CysTrp: 1.178 ± 0.567
0.785CysTyr: 0.785 ± 0.31
0.0CysXaa: 0.0 ± 0.0
Asp
7.46AspAla: 7.46 ± 0.851
1.178AspCys: 1.178 ± 0.567
4.319AspAsp: 4.319 ± 1.388
4.319AspGlu: 4.319 ± 0.949
1.963AspPhe: 1.963 ± 0.455
5.104AspGly: 5.104 ± 0.562
1.963AspHis: 1.963 ± 0.509
2.356AspIle: 2.356 ± 1.134
3.141AspLys: 3.141 ± 1.674
5.104AspLeu: 5.104 ± 2.562
0.393AspMet: 0.393 ± 0.475
1.57AspAsn: 1.57 ± 0.37
2.356AspPro: 2.356 ± 0.539
0.785AspGln: 0.785 ± 0.31
3.141AspArg: 3.141 ± 0.941
4.711AspSer: 4.711 ± 1.252
4.319AspThr: 4.319 ± 1.625
6.675AspVal: 6.675 ± 1.543
1.178AspTrp: 1.178 ± 0.773
1.963AspTyr: 1.963 ± 1.002
0.0AspXaa: 0.0 ± 0.0
Glu
3.926GluAla: 3.926 ± 0.713
1.178GluCys: 1.178 ± 0.494
3.926GluAsp: 3.926 ± 0.613
3.534GluGlu: 3.534 ± 0.854
1.178GluPhe: 1.178 ± 0.793
1.178GluGly: 1.178 ± 0.627
0.0GluHis: 0.0 ± 0.0
3.926GluIle: 3.926 ± 0.944
4.711GluLys: 4.711 ± 0.519
5.104GluLeu: 5.104 ± 0.822
1.57GluMet: 1.57 ± 1.194
0.785GluAsn: 0.785 ± 0.556
1.57GluPro: 1.57 ± 0.621
1.963GluGln: 1.963 ± 0.917
3.141GluArg: 3.141 ± 0.683
1.963GluSer: 1.963 ± 0.509
2.748GluThr: 2.748 ± 1.227
5.497GluVal: 5.497 ± 0.938
0.0GluTrp: 0.0 ± 0.0
2.356GluTyr: 2.356 ± 1.134
0.0GluXaa: 0.0 ± 0.0
Phe
2.356PheAla: 2.356 ± 0.837
0.393PheCys: 0.393 ± 0.278
2.748PheAsp: 2.748 ± 1.093
2.356PheGlu: 2.356 ± 0.849
0.393PhePhe: 0.393 ± 0.278
1.178PheGly: 1.178 ± 0.56
1.178PheHis: 1.178 ± 0.567
3.534PheIle: 3.534 ± 1.728
1.57PheLys: 1.57 ± 0.868
3.926PheLeu: 3.926 ± 1.547
0.785PheMet: 0.785 ± 0.556
1.57PheAsn: 1.57 ± 0.532
3.141PhePro: 3.141 ± 1.653
1.57PheGln: 1.57 ± 0.621
3.141PheArg: 3.141 ± 0.846
4.319PheSer: 4.319 ± 0.303
1.57PheThr: 1.57 ± 0.444
3.926PheVal: 3.926 ± 1.554
0.785PheTrp: 0.785 ± 0.504
1.57PheTyr: 1.57 ± 0.739
0.0PheXaa: 0.0 ± 0.0
Gly
2.356GlyAla: 2.356 ± 0.607
2.356GlyCys: 2.356 ± 1.063
3.926GlyAsp: 3.926 ± 1.46
1.178GlyGlu: 1.178 ± 0.711
3.534GlyPhe: 3.534 ± 1.882
1.963GlyGly: 1.963 ± 0.777
0.785GlyHis: 0.785 ± 0.531
1.963GlyIle: 1.963 ± 0.777
4.319GlyLys: 4.319 ± 0.665
3.926GlyLeu: 3.926 ± 1.924
1.963GlyMet: 1.963 ± 0.939
2.356GlyAsn: 2.356 ± 0.952
1.963GlyPro: 1.963 ± 1.213
0.393GlyGln: 0.393 ± 0.514
4.319GlyArg: 4.319 ± 1.118
4.319GlySer: 4.319 ± 0.782
3.926GlyThr: 3.926 ± 1.308
3.926GlyVal: 3.926 ± 1.582
1.178GlyTrp: 1.178 ± 0.88
0.393GlyTyr: 0.393 ± 0.604
0.0GlyXaa: 0.0 ± 0.0
His
2.356HisAla: 2.356 ± 0.659
0.785HisCys: 0.785 ± 0.556
1.178HisAsp: 1.178 ± 0.567
1.963HisGlu: 1.963 ± 0.82
1.57HisPhe: 1.57 ± 0.528
0.393HisGly: 0.393 ± 0.596
1.178HisHis: 1.178 ± 0.963
1.963HisIle: 1.963 ± 0.409
1.57HisLys: 1.57 ± 0.621
1.178HisLeu: 1.178 ± 1.157
0.393HisMet: 0.393 ± 0.321
1.57HisAsn: 1.57 ± 0.621
0.393HisPro: 0.393 ± 0.604
0.785HisGln: 0.785 ± 0.642
1.57HisArg: 1.57 ± 0.868
1.963HisSer: 1.963 ± 1.002
1.178HisThr: 1.178 ± 0.494
1.178HisVal: 1.178 ± 0.433
0.393HisTrp: 0.393 ± 0.321
0.785HisTyr: 0.785 ± 0.556
0.0HisXaa: 0.0 ± 0.0
Ile
5.104IleAla: 5.104 ± 1.136
0.785IleCys: 0.785 ± 0.531
2.748IleAsp: 2.748 ± 1.408
2.356IleGlu: 2.356 ± 1.326
1.57IlePhe: 1.57 ± 1.194
3.141IleGly: 3.141 ± 0.846
1.57IleHis: 1.57 ± 0.621
3.534IleIle: 3.534 ± 1.121
3.141IleLys: 3.141 ± 1.18
3.141IleLeu: 3.141 ± 0.74
1.178IleMet: 1.178 ± 0.567
1.57IleAsn: 1.57 ± 0.803
6.282IlePro: 6.282 ± 1.688
1.963IleGln: 1.963 ± 0.618
1.57IleArg: 1.57 ± 0.742
3.926IleSer: 3.926 ± 1.018
3.534IleThr: 3.534 ± 0.888
3.926IleVal: 3.926 ± 1.136
0.785IleTrp: 0.785 ± 0.531
2.356IleTyr: 2.356 ± 0.635
0.0IleXaa: 0.0 ± 0.0
Lys
3.141LysAla: 3.141 ± 1.024
1.57LysCys: 1.57 ± 0.985
1.963LysAsp: 1.963 ± 0.871
3.141LysGlu: 3.141 ± 0.872
3.141LysPhe: 3.141 ± 0.846
1.963LysGly: 1.963 ± 0.73
1.178LysHis: 1.178 ± 0.494
3.534LysIle: 3.534 ± 1.111
5.889LysLys: 5.889 ± 1.273
2.748LysLeu: 2.748 ± 0.65
3.534LysMet: 3.534 ± 0.845
3.926LysAsn: 3.926 ± 1.607
4.711LysPro: 4.711 ± 0.852
2.356LysGln: 2.356 ± 1.096
2.748LysArg: 2.748 ± 1.221
6.282LysSer: 6.282 ± 0.541
4.711LysThr: 4.711 ± 1.681
4.319LysVal: 4.319 ± 0.865
1.57LysTrp: 1.57 ± 0.868
2.356LysTyr: 2.356 ± 0.53
0.0LysXaa: 0.0 ± 0.0
Leu
3.926LeuAla: 3.926 ± 0.774
2.748LeuCys: 2.748 ± 1.365
4.319LeuAsp: 4.319 ± 1.767
5.497LeuGlu: 5.497 ± 1.262
2.748LeuPhe: 2.748 ± 1.05
2.748LeuGly: 2.748 ± 1.514
1.963LeuHis: 1.963 ± 1.021
3.141LeuIle: 3.141 ± 0.829
7.46LeuLys: 7.46 ± 0.636
7.46LeuLeu: 7.46 ± 1.106
2.748LeuMet: 2.748 ± 1.285
2.748LeuAsn: 2.748 ± 1.041
5.104LeuPro: 5.104 ± 1.218
1.963LeuGln: 1.963 ± 0.761
4.319LeuArg: 4.319 ± 1.54
7.067LeuSer: 7.067 ± 1.88
3.141LeuThr: 3.141 ± 1.672
9.423LeuVal: 9.423 ± 2.358
0.393LeuTrp: 0.393 ± 0.604
3.141LeuTyr: 3.141 ± 0.452
0.0LeuXaa: 0.0 ± 0.0
Met
1.963MetAla: 1.963 ± 1.035
0.393MetCys: 0.393 ± 0.596
2.356MetAsp: 2.356 ± 0.539
0.785MetGlu: 0.785 ± 0.545
0.393MetPhe: 0.393 ± 0.604
0.785MetGly: 0.785 ± 0.31
0.393MetHis: 0.393 ± 0.321
2.356MetIle: 2.356 ± 0.607
2.748MetLys: 2.748 ± 1.148
2.748MetLeu: 2.748 ± 0.428
1.178MetMet: 1.178 ± 0.494
1.57MetAsn: 1.57 ± 0.621
2.356MetPro: 2.356 ± 0.635
1.57MetGln: 1.57 ± 0.621
1.963MetArg: 1.963 ± 1.035
1.963MetSer: 1.963 ± 0.917
1.963MetThr: 1.963 ± 0.777
1.963MetVal: 1.963 ± 0.987
1.57MetTrp: 1.57 ± 0.979
0.785MetTyr: 0.785 ± 0.531
0.0MetXaa: 0.0 ± 0.0
Asn
3.141AsnAla: 3.141 ± 1.903
1.178AsnCys: 1.178 ± 1.084
2.748AsnAsp: 2.748 ± 0.782
1.178AsnGlu: 1.178 ± 1.084
2.356AsnPhe: 2.356 ± 0.659
2.356AsnGly: 2.356 ± 0.908
1.57AsnHis: 1.57 ± 0.621
2.748AsnIle: 2.748 ± 0.782
1.963AsnLys: 1.963 ± 0.618
3.926AsnLeu: 3.926 ± 2.24
0.785AsnMet: 0.785 ± 0.597
1.963AsnAsn: 1.963 ± 2.212
3.141AsnPro: 3.141 ± 0.846
1.963AsnGln: 1.963 ± 1.179
1.57AsnArg: 1.57 ± 0.868
1.57AsnSer: 1.57 ± 0.532
2.748AsnThr: 2.748 ± 1.156
2.748AsnVal: 2.748 ± 1.368
0.393AsnTrp: 0.393 ± 0.514
1.57AsnTyr: 1.57 ± 0.803
0.0AsnXaa: 0.0 ± 0.0
Pro
1.57ProAla: 1.57 ± 1.299
0.0ProCys: 0.0 ± 0.0
4.319ProAsp: 4.319 ± 1.173
1.963ProGlu: 1.963 ± 0.604
1.57ProPhe: 1.57 ± 0.532
3.534ProGly: 3.534 ± 0.888
1.178ProHis: 1.178 ± 0.411
3.141ProIle: 3.141 ± 1.478
2.356ProLys: 2.356 ± 1.056
4.319ProLeu: 4.319 ± 2.567
3.926ProMet: 3.926 ± 1.022
2.748ProAsn: 2.748 ± 1.057
2.356ProPro: 2.356 ± 1.235
2.356ProGln: 2.356 ± 1.442
3.926ProArg: 3.926 ± 1.105
3.534ProSer: 3.534 ± 1.056
2.356ProThr: 2.356 ± 1.905
4.711ProVal: 4.711 ± 2.463
0.785ProTrp: 0.785 ± 0.545
0.393ProTyr: 0.393 ± 0.278
0.0ProXaa: 0.0 ± 0.0
Gln
1.963GlnAla: 1.963 ± 0.777
1.57GlnCys: 1.57 ± 0.721
1.178GlnAsp: 1.178 ± 0.567
1.178GlnGlu: 1.178 ± 0.43
1.178GlnPhe: 1.178 ± 0.433
2.748GlnGly: 2.748 ± 1.156
0.0GlnHis: 0.0 ± 0.0
1.57GlnIle: 1.57 ± 0.37
0.393GlnLys: 0.393 ± 0.604
1.57GlnLeu: 1.57 ± 1.194
1.57GlnMet: 1.57 ± 0.924
0.393GlnAsn: 0.393 ± 0.604
2.356GlnPro: 2.356 ± 0.849
0.393GlnGln: 0.393 ± 0.514
1.57GlnArg: 1.57 ± 0.528
2.748GlnSer: 2.748 ± 0.782
3.141GlnThr: 3.141 ± 0.846
2.356GlnVal: 2.356 ± 0.908
1.178GlnTrp: 1.178 ± 0.979
1.963GlnTyr: 1.963 ± 0.777
0.0GlnXaa: 0.0 ± 0.0
Arg
1.963ArgAla: 1.963 ± 0.917
0.785ArgCys: 0.785 ± 0.545
4.319ArgAsp: 4.319 ± 1.756
3.141ArgGlu: 3.141 ± 1.419
2.748ArgPhe: 2.748 ± 0.65
4.319ArgGly: 4.319 ± 1.718
1.178ArgHis: 1.178 ± 0.494
2.748ArgIle: 2.748 ± 1.091
2.748ArgLys: 2.748 ± 1.075
5.889ArgLeu: 5.889 ± 0.875
1.178ArgMet: 1.178 ± 1.549
3.141ArgAsn: 3.141 ± 0.882
1.963ArgPro: 1.963 ± 0.604
1.57ArgGln: 1.57 ± 0.739
3.534ArgArg: 3.534 ± 0.946
5.104ArgSer: 5.104 ± 2.596
1.57ArgThr: 1.57 ± 0.739
6.675ArgVal: 6.675 ± 0.902
1.57ArgTrp: 1.57 ± 1.226
1.963ArgTyr: 1.963 ± 0.509
0.0ArgXaa: 0.0 ± 0.0
Ser
3.141SerAla: 3.141 ± 1.736
1.57SerCys: 1.57 ± 0.739
4.319SerAsp: 4.319 ± 1.331
2.748SerGlu: 2.748 ± 1.049
5.104SerPhe: 5.104 ± 1.088
5.889SerGly: 5.889 ± 0.542
1.57SerHis: 1.57 ± 0.444
2.748SerIle: 2.748 ± 0.714
3.926SerLys: 3.926 ± 1.105
5.497SerLeu: 5.497 ± 1.115
2.748SerMet: 2.748 ± 0.616
3.534SerAsn: 3.534 ± 0.597
1.57SerPro: 1.57 ± 0.85
3.534SerGln: 3.534 ± 0.421
7.067SerArg: 7.067 ± 1.786
5.889SerSer: 5.889 ± 1.05
2.748SerThr: 2.748 ± 0.631
7.46SerVal: 7.46 ± 1.051
1.178SerTrp: 1.178 ± 0.43
3.141SerTyr: 3.141 ± 0.683
0.0SerXaa: 0.0 ± 0.0
Thr
5.104ThrAla: 5.104 ± 2.976
0.785ThrCys: 0.785 ± 0.31
3.534ThrAsp: 3.534 ± 0.907
2.748ThrGlu: 2.748 ± 1.3
2.356ThrPhe: 2.356 ± 1.134
3.534ThrGly: 3.534 ± 0.726
1.963ThrHis: 1.963 ± 0.777
3.141ThrIle: 3.141 ± 0.759
2.748ThrLys: 2.748 ± 0.664
5.889ThrLeu: 5.889 ± 1.182
1.57ThrMet: 1.57 ± 0.498
2.356ThrAsn: 2.356 ± 1.617
1.178ThrPro: 1.178 ± 0.631
1.963ThrGln: 1.963 ± 0.551
2.748ThrArg: 2.748 ± 0.893
3.141ThrSer: 3.141 ± 0.683
3.926ThrThr: 3.926 ± 0.931
3.926ThrVal: 3.926 ± 1.763
1.178ThrTrp: 1.178 ± 0.631
1.178ThrTyr: 1.178 ± 0.567
0.0ThrXaa: 0.0 ± 0.0
Val
5.104ValAla: 5.104 ± 1.861
1.57ValCys: 1.57 ± 0.572
5.889ValAsp: 5.889 ± 1.147
4.711ValGlu: 4.711 ± 1.673
3.141ValPhe: 3.141 ± 0.902
2.356ValGly: 2.356 ± 1.107
2.356ValHis: 2.356 ± 0.53
5.497ValIle: 5.497 ± 1.233
9.815ValLys: 9.815 ± 0.665
5.497ValLeu: 5.497 ± 1.262
1.963ValMet: 1.963 ± 0.569
4.319ValAsn: 4.319 ± 1.309
5.104ValPro: 5.104 ± 1.746
1.963ValGln: 1.963 ± 0.871
3.534ValArg: 3.534 ± 1.679
6.282ValSer: 6.282 ± 1.507
5.104ValThr: 5.104 ± 1.094
6.282ValVal: 6.282 ± 1.952
1.178ValTrp: 1.178 ± 0.494
2.356ValTyr: 2.356 ± 0.859
0.0ValXaa: 0.0 ± 0.0
Trp
1.57TrpAla: 1.57 ± 0.632
0.0TrpCys: 0.0 ± 0.0
1.178TrpAsp: 1.178 ± 0.56
2.356TrpGlu: 2.356 ± 0.956
1.178TrpPhe: 1.178 ± 0.567
0.393TrpGly: 0.393 ± 0.278
0.785TrpHis: 0.785 ± 0.531
0.785TrpIle: 0.785 ± 0.597
0.785TrpLys: 0.785 ± 0.504
1.963TrpLeu: 1.963 ± 1.179
0.393TrpMet: 0.393 ± 0.278
1.178TrpAsn: 1.178 ± 0.433
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.393TrpArg: 0.393 ± 0.278
1.57TrpSer: 1.57 ± 0.632
0.0TrpThr: 0.0 ± 0.0
1.178TrpVal: 1.178 ± 0.717
0.393TrpTrp: 0.393 ± 0.278
1.178TrpTyr: 1.178 ± 1.391
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.963TyrAla: 1.963 ± 1.073
1.178TyrCys: 1.178 ± 0.631
2.748TyrAsp: 2.748 ± 0.631
1.57TyrGlu: 1.57 ± 1.112
1.57TyrPhe: 1.57 ± 0.868
1.57TyrGly: 1.57 ± 1.285
1.57TyrHis: 1.57 ± 0.868
1.178TyrIle: 1.178 ± 0.834
1.178TyrLys: 1.178 ± 0.56
3.534TyrLeu: 3.534 ± 1.122
1.57TyrMet: 1.57 ± 0.532
0.393TyrAsn: 0.393 ± 0.321
0.785TyrPro: 0.785 ± 0.597
2.356TyrGln: 2.356 ± 1.509
3.141TyrArg: 3.141 ± 0.491
3.141TyrSer: 3.141 ± 1.275
1.963TyrThr: 1.963 ± 1.31
2.356TyrVal: 2.356 ± 1.134
0.0TyrTrp: 0.0 ± 0.0
0.785TyrTyr: 0.785 ± 0.31
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2548 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski