Amino acid dipepetide frequency for Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.028AlaAla: 4.028 ± 0.063	0.565AlaCys: 0.565 ± 0.028	3.426AlaAsp: 3.426 ± 0.058	4.093AlaGlu: 4.093 ± 0.062	3.419AlaPhe: 3.419 ± 0.05	3.93AlaGly: 3.93 ± 0.068	1.187AlaHis: 1.187 ± 0.032	5.359AlaIle: 5.359 ± 0.087	4.589AlaLys: 4.589 ± 0.076	6.556AlaLeu: 6.556 ± 0.09	1.5AlaMet: 1.5 ± 0.041	3.484AlaAsn: 3.484 ± 0.06	2.013AlaPro: 2.013 ± 0.046	2.364AlaGln: 2.364 ± 0.052	1.83AlaArg: 1.83 ± 0.049	4.3AlaSer: 4.3 ± 0.066	3.683AlaThr: 3.683 ± 0.068	4.192AlaVal: 4.192 ± 0.059	0.707AlaTrp: 0.707 ± 0.025	2.673AlaTyr: 2.673 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.414CysAla: 0.414 ± 0.019	0.101CysCys: 0.101 ± 0.01	0.425CysAsp: 0.425 ± 0.02	0.452CysGlu: 0.452 ± 0.019	0.422CysPhe: 0.422 ± 0.019	0.572CysGly: 0.572 ± 0.028	0.18CysHis: 0.18 ± 0.015	0.564CysIle: 0.564 ± 0.019	0.5CysLys: 0.5 ± 0.02	0.658CysLeu: 0.658 ± 0.025	0.151CysMet: 0.151 ± 0.01	0.395CysAsn: 0.395 ± 0.021	0.28CysPro: 0.28 ± 0.019	0.196CysGln: 0.196 ± 0.013	0.189CysArg: 0.189 ± 0.011	0.511CysSer: 0.511 ± 0.025	0.412CysThr: 0.412 ± 0.018	0.438CysVal: 0.438 ± 0.021	0.065CysTrp: 0.065 ± 0.007	0.315CysTyr: 0.315 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.112AspAla: 4.112 ± 0.072	0.425AspCys: 0.425 ± 0.019	3.335AspAsp: 3.335 ± 0.063	3.782AspGlu: 3.782 ± 0.057	3.697AspPhe: 3.697 ± 0.054	3.888AspGly: 3.888 ± 0.086	0.936AspHis: 0.936 ± 0.027	4.821AspIle: 4.821 ± 0.068	4.06AspLys: 4.06 ± 0.072	5.589AspLeu: 5.589 ± 0.079	1.246AspMet: 1.246 ± 0.031	3.343AspAsn: 3.343 ± 0.059	1.637AspPro: 1.637 ± 0.039	1.564AspGln: 1.564 ± 0.037	1.79AspArg: 1.79 ± 0.04	3.447AspSer: 3.447 ± 0.059	3.151AspThr: 3.151 ± 0.051	4.153AspVal: 4.153 ± 0.057	0.822AspTrp: 0.822 ± 0.026	3.117AspTyr: 3.117 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	4.802GluAla: 4.802 ± 0.078	0.317GluCys: 0.317 ± 0.017	4.097GluAsp: 4.097 ± 0.062	4.065GluGlu: 4.065 ± 0.075	3.041GluPhe: 3.041 ± 0.056	3.797GluGly: 3.797 ± 0.062	1.437GluHis: 1.437 ± 0.03	5.111GluIle: 5.111 ± 0.07	4.759GluLys: 4.759 ± 0.066	6.127GluLeu: 6.127 ± 0.07	1.363GluMet: 1.363 ± 0.034	4.395GluAsn: 4.395 ± 0.06	1.598GluPro: 1.598 ± 0.036	2.382GluGln: 2.382 ± 0.041	2.427GluArg: 2.427 ± 0.05	3.643GluSer: 3.643 ± 0.053	4.11GluThr: 4.11 ± 0.064	4.127GluVal: 4.127 ± 0.07	0.627GluTrp: 0.627 ± 0.025	2.311GluTyr: 2.311 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	2.762PheAla: 2.762 ± 0.053	0.409PheCys: 0.409 ± 0.02	3.187PheAsp: 3.187 ± 0.049	3.439PheGlu: 3.439 ± 0.051	2.48PhePhe: 2.48 ± 0.05	3.527PheGly: 3.527 ± 0.058	0.836PheHis: 0.836 ± 0.027	3.95PheIle: 3.95 ± 0.074	4.149PheLys: 4.149 ± 0.064	4.334PheLeu: 4.334 ± 0.074	1.146PheMet: 1.146 ± 0.031	3.623PheAsn: 3.623 ± 0.061	1.644PhePro: 1.644 ± 0.04	1.551PheGln: 1.551 ± 0.041	1.568PheArg: 1.568 ± 0.036	3.979PheSer: 3.979 ± 0.054	3.04PheThr: 3.04 ± 0.059	2.982PheVal: 2.982 ± 0.047	0.571PheTrp: 0.571 ± 0.025	2.154PheTyr: 2.154 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	4.246GlyAla: 4.246 ± 0.076	0.533GlyCys: 0.533 ± 0.021	3.57GlyAsp: 3.57 ± 0.07	3.68GlyGlu: 3.68 ± 0.066	3.651GlyPhe: 3.651 ± 0.062	4.559GlyGly: 4.559 ± 0.089	1.213GlyHis: 1.213 ± 0.035	5.232GlyIle: 5.232 ± 0.07	4.565GlyLys: 4.565 ± 0.071	5.885GlyLeu: 5.885 ± 0.073	1.52GlyMet: 1.52 ± 0.035	3.38GlyAsn: 3.38 ± 0.075	1.423GlyPro: 1.423 ± 0.038	1.838GlyGln: 1.838 ± 0.045	2.086GlyArg: 2.086 ± 0.046	3.862GlySer: 3.862 ± 0.075	4.133GlyThr: 4.133 ± 0.082	4.646GlyVal: 4.646 ± 0.074	0.788GlyTrp: 0.788 ± 0.028	2.976GlyTyr: 2.976 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.074HisAla: 1.074 ± 0.03	0.161HisCys: 0.161 ± 0.011	1.046HisAsp: 1.046 ± 0.027	0.988HisGlu: 0.988 ± 0.028	1.229HisPhe: 1.229 ± 0.031	1.181HisGly: 1.181 ± 0.034	0.502HisHis: 0.502 ± 0.023	1.598HisIle: 1.598 ± 0.033	1.262HisLys: 1.262 ± 0.029	1.921HisLeu: 1.921 ± 0.04	0.379HisMet: 0.379 ± 0.018	1.081HisAsn: 1.081 ± 0.03	0.926HisPro: 0.926 ± 0.029	0.654HisGln: 0.654 ± 0.026	0.62HisArg: 0.62 ± 0.022	1.13HisSer: 1.13 ± 0.035	1.046HisThr: 1.046 ± 0.03	1.163HisVal: 1.163 ± 0.033	0.25HisTrp: 0.25 ± 0.015	0.878HisTyr: 0.878 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.371IleAla: 5.371 ± 0.083	0.632IleCys: 0.632 ± 0.022	4.947IleAsp: 4.947 ± 0.071	5.382IleGlu: 5.382 ± 0.076	3.42IlePhe: 3.42 ± 0.06	4.97IleGly: 4.97 ± 0.069	1.427IleHis: 1.427 ± 0.039	5.895IleIle: 5.895 ± 0.093	5.755IleLys: 5.755 ± 0.087	6.897IleLeu: 6.897 ± 0.09	1.459IleMet: 1.459 ± 0.039	4.73IleAsn: 4.73 ± 0.072	3.295IlePro: 3.295 ± 0.06	2.575IleGln: 2.575 ± 0.047	2.368IleArg: 2.368 ± 0.045	5.799IleSer: 5.799 ± 0.074	5.012IleThr: 5.012 ± 0.072	4.72IleVal: 4.72 ± 0.061	0.718IleTrp: 0.718 ± 0.027	2.813IleTyr: 2.813 ± 0.053	0.0IleXaa: 0.0 ± 0.0
Lys	5.131LysAla: 5.131 ± 0.076	0.302LysCys: 0.302 ± 0.015	4.727LysAsp: 4.727 ± 0.072	5.084LysGlu: 5.084 ± 0.076	2.841LysPhe: 2.841 ± 0.047	4.308LysGly: 4.308 ± 0.064	1.668LysHis: 1.668 ± 0.039	5.52LysIle: 5.52 ± 0.083	5.672LysLys: 5.672 ± 0.097	6.377LysLeu: 6.377 ± 0.086	1.827LysMet: 1.827 ± 0.044	4.925LysAsn: 4.925 ± 0.082	2.565LysPro: 2.565 ± 0.049	2.903LysGln: 2.903 ± 0.057	2.792LysArg: 2.792 ± 0.06	4.867LysSer: 4.867 ± 0.064	5.137LysThr: 5.137 ± 0.071	4.328LysVal: 4.328 ± 0.065	0.756LysTrp: 0.756 ± 0.025	2.941LysTyr: 2.941 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	5.596LeuAla: 5.596 ± 0.075	0.72LeuCys: 0.72 ± 0.023	5.391LeuAsp: 5.391 ± 0.058	6.318LeuGlu: 6.318 ± 0.084	4.555LeuPhe: 4.555 ± 0.077	5.989LeuGly: 5.989 ± 0.074	1.603LeuHis: 1.603 ± 0.039	6.906LeuIle: 6.906 ± 0.093	7.981LeuLys: 7.981 ± 0.096	8.231LeuLeu: 8.231 ± 0.115	1.951LeuMet: 1.951 ± 0.044	6.149LeuAsn: 6.149 ± 0.083	3.538LeuPro: 3.538 ± 0.055	3.244LeuGln: 3.244 ± 0.057	2.984LeuArg: 2.984 ± 0.051	6.373LeuSer: 6.373 ± 0.08	5.138LeuThr: 5.138 ± 0.07	5.383LeuVal: 5.383 ± 0.067	0.852LeuTrp: 0.852 ± 0.028	3.215LeuTyr: 3.215 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.551MetAla: 1.551 ± 0.036	0.165MetCys: 0.165 ± 0.013	1.117MetAsp: 1.117 ± 0.034	1.242MetGlu: 1.242 ± 0.036	0.96MetPhe: 0.96 ± 0.034	1.31MetGly: 1.31 ± 0.039	0.456MetHis: 0.456 ± 0.02	1.461MetIle: 1.461 ± 0.036	1.98MetLys: 1.98 ± 0.043	1.986MetLeu: 1.986 ± 0.041	0.536MetMet: 0.536 ± 0.025	1.226MetAsn: 1.226 ± 0.032	0.875MetPro: 0.875 ± 0.029	0.812MetGln: 0.812 ± 0.025	0.762MetArg: 0.762 ± 0.024	1.494MetSer: 1.494 ± 0.034	1.127MetThr: 1.127 ± 0.035	1.339MetVal: 1.339 ± 0.034	0.19MetTrp: 0.19 ± 0.012	0.821MetTyr: 0.821 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.823AsnAla: 3.823 ± 0.056	0.42AsnCys: 0.42 ± 0.02	3.358AsnAsp: 3.358 ± 0.058	3.77AsnGlu: 3.77 ± 0.057	2.933AsnPhe: 2.933 ± 0.052	3.971AsnGly: 3.971 ± 0.089	1.189AsnHis: 1.189 ± 0.033	5.08AsnIle: 5.08 ± 0.08	4.292AsnLys: 4.292 ± 0.064	5.498AsnLeu: 5.498 ± 0.073	1.317AsnMet: 1.317 ± 0.034	4.02AsnAsn: 4.02 ± 0.077	2.798AsnPro: 2.798 ± 0.054	2.234AsnGln: 2.234 ± 0.041	2.134AsnArg: 2.134 ± 0.045	3.84AsnSer: 3.84 ± 0.068	4.289AsnThr: 4.289 ± 0.07	3.627AsnVal: 3.627 ± 0.067	0.807AsnTrp: 0.807 ± 0.029	2.969AsnTyr: 2.969 ± 0.058	0.0AsnXaa: 0.0 ± 0.0
Pro	1.831ProAla: 1.831 ± 0.041	0.2ProCys: 0.2 ± 0.013	2.016ProAsp: 2.016 ± 0.04	3.119ProGlu: 3.119 ± 0.052	1.922ProPhe: 1.922 ± 0.036	1.895ProGly: 1.895 ± 0.045	0.667ProHis: 0.667 ± 0.025	2.747ProIle: 2.747 ± 0.045	2.638ProLys: 2.638 ± 0.048	3.045ProLeu: 3.045 ± 0.059	0.718ProMet: 0.718 ± 0.023	2.414ProAsn: 2.414 ± 0.048	0.725ProPro: 0.725 ± 0.024	1.107ProGln: 1.107 ± 0.031	0.916ProArg: 0.916 ± 0.028	2.152ProSer: 2.152 ± 0.046	2.051ProThr: 2.051 ± 0.037	2.212ProVal: 2.212 ± 0.051	0.409ProTrp: 0.409 ± 0.02	1.423ProTyr: 1.423 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	2.176GlnAla: 2.176 ± 0.042	0.153GlnCys: 0.153 ± 0.012	2.047GlnAsp: 2.047 ± 0.041	2.12GlnGlu: 2.12 ± 0.046	1.801GlnPhe: 1.801 ± 0.037	1.925GlnGly: 1.925 ± 0.041	0.699GlnHis: 0.699 ± 0.03	2.54GlnIle: 2.54 ± 0.04	2.413GlnLys: 2.413 ± 0.049	3.385GlnLeu: 3.385 ± 0.063	0.746GlnMet: 0.746 ± 0.024	2.164GlnAsn: 2.164 ± 0.049	1.116GlnPro: 1.116 ± 0.031	1.29GlnGln: 1.29 ± 0.043	1.121GlnArg: 1.121 ± 0.033	2.056GlnSer: 2.056 ± 0.041	1.983GlnThr: 1.983 ± 0.039	2.046GlnVal: 2.046 ± 0.038	0.369GlnTrp: 0.369 ± 0.017	1.339GlnTyr: 1.339 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	2.059ArgAla: 2.059 ± 0.046	0.198ArgCys: 0.198 ± 0.014	1.815ArgAsp: 1.815 ± 0.042	1.919ArgGlu: 1.919 ± 0.047	1.825ArgPhe: 1.825 ± 0.035	1.93ArgGly: 1.93 ± 0.044	0.636ArgHis: 0.636 ± 0.02	2.664ArgIle: 2.664 ± 0.046	2.317ArgLys: 2.317 ± 0.05	3.188ArgLeu: 3.188 ± 0.047	0.805ArgMet: 0.805 ± 0.026	1.91ArgAsn: 1.91 ± 0.04	1.152ArgPro: 1.152 ± 0.031	1.037ArgGln: 1.037 ± 0.03	1.185ArgArg: 1.185 ± 0.034	1.816ArgSer: 1.816 ± 0.038	1.965ArgThr: 1.965 ± 0.045	2.124ArgVal: 2.124 ± 0.041	0.403ArgTrp: 0.403 ± 0.019	1.491ArgTyr: 1.491 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.838SerAla: 3.838 ± 0.063	0.602SerCys: 0.602 ± 0.023	3.796SerAsp: 3.796 ± 0.06	4.522SerGlu: 4.522 ± 0.054	3.514SerPhe: 3.514 ± 0.054	4.696SerGly: 4.696 ± 0.093	1.196SerHis: 1.196 ± 0.031	5.243SerIle: 5.243 ± 0.065	5.189SerLys: 5.189 ± 0.077	5.696SerLeu: 5.696 ± 0.075	1.284SerMet: 1.284 ± 0.033	4.04SerAsn: 4.04 ± 0.066	2.118SerPro: 2.118 ± 0.04	2.18SerGln: 2.18 ± 0.046	2.127SerArg: 2.127 ± 0.04	4.241SerSer: 4.241 ± 0.072	3.756SerThr: 3.756 ± 0.073	4.11SerVal: 4.11 ± 0.064	0.731SerTrp: 0.731 ± 0.028	2.774SerTyr: 2.774 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	3.902ThrAla: 3.902 ± 0.065	0.376ThrCys: 0.376 ± 0.018	3.721ThrAsp: 3.721 ± 0.066	3.78ThrGlu: 3.78 ± 0.058	3.166ThrPhe: 3.166 ± 0.051	4.018ThrGly: 4.018 ± 0.08	1.147ThrHis: 1.147 ± 0.034	5.04ThrIle: 5.04 ± 0.079	3.985ThrLys: 3.985 ± 0.06	5.794ThrLeu: 5.794 ± 0.071	1.016ThrMet: 1.016 ± 0.028	3.509ThrAsn: 3.509 ± 0.064	2.526ThrPro: 2.526 ± 0.049	1.948ThrGln: 1.948 ± 0.044	1.707ThrArg: 1.707 ± 0.039	3.98ThrSer: 3.98 ± 0.06	3.86ThrThr: 3.86 ± 0.085	3.982ThrVal: 3.982 ± 0.072	0.699ThrTrp: 0.699 ± 0.025	2.677ThrTyr: 2.677 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.014ValAla: 4.014 ± 0.066	0.55ValCys: 0.55 ± 0.021	3.799ValAsp: 3.799 ± 0.06	3.878ValGlu: 3.878 ± 0.062	3.498ValPhe: 3.498 ± 0.06	3.859ValGly: 3.859 ± 0.065	1.002ValHis: 1.002 ± 0.031	4.8ValIle: 4.8 ± 0.071	4.446ValLys: 4.446 ± 0.068	6.208ValLeu: 6.208 ± 0.076	1.327ValMet: 1.327 ± 0.033	3.804ValAsn: 3.804 ± 0.065	2.156ValPro: 2.156 ± 0.045	1.724ValGln: 1.724 ± 0.038	1.949ValArg: 1.949 ± 0.041	4.677ValSer: 4.677 ± 0.076	3.718ValThr: 3.718 ± 0.061	4.268ValVal: 4.268 ± 0.06	0.671ValTrp: 0.671 ± 0.024	2.526ValTyr: 2.526 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.623TrpAla: 0.623 ± 0.024	0.111TrpCys: 0.111 ± 0.009	0.704TrpAsp: 0.704 ± 0.023	0.715TrpGlu: 0.715 ± 0.023	0.575TrpPhe: 0.575 ± 0.025	0.736TrpGly: 0.736 ± 0.027	0.266TrpHis: 0.266 ± 0.015	0.753TrpIle: 0.753 ± 0.027	0.811TrpLys: 0.811 ± 0.027	1.002TrpLeu: 1.002 ± 0.034	0.335TrpMet: 0.335 ± 0.016	0.744TrpAsn: 0.744 ± 0.028	0.313TrpPro: 0.313 ± 0.018	0.414TrpGln: 0.414 ± 0.019	0.402TrpArg: 0.402 ± 0.019	0.739TrpSer: 0.739 ± 0.025	0.619TrpThr: 0.619 ± 0.028	0.644TrpVal: 0.644 ± 0.026	0.168TrpTrp: 0.168 ± 0.012	0.46TrpTyr: 0.46 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.544TyrAla: 2.544 ± 0.045	0.305TyrCys: 0.305 ± 0.017	2.393TyrAsp: 2.393 ± 0.052	2.187TyrGlu: 2.187 ± 0.038	2.384TyrPhe: 2.384 ± 0.05	2.725TyrGly: 2.725 ± 0.049	0.843TyrHis: 0.843 ± 0.027	2.902TyrIle: 2.902 ± 0.055	3.307TyrLys: 3.307 ± 0.052	3.739TyrLeu: 3.739 ± 0.058	0.783TyrMet: 0.783 ± 0.023	3.033TyrAsn: 3.033 ± 0.057	1.506TyrPro: 1.506 ± 0.036	1.472TyrGln: 1.472 ± 0.038	1.48TyrArg: 1.48 ± 0.04	2.744TyrSer: 2.744 ± 0.054	2.602TyrThr: 2.602 ± 0.054	2.393TyrVal: 2.393 ± 0.047	0.533TyrTrp: 0.533 ± 0.02	1.949TyrTyr: 1.949 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3557 proteins (1231760 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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