Amino acid dipepetide frequency for Sphingorhabdus contaminans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.587AlaAla: 15.587 ± 0.205	1.0AlaCys: 1.0 ± 0.036	6.978AlaAsp: 6.978 ± 0.09	7.256AlaGlu: 7.256 ± 0.103	4.326AlaPhe: 4.326 ± 0.066	9.969AlaGly: 9.969 ± 0.125	2.222AlaHis: 2.222 ± 0.044	6.881AlaIle: 6.881 ± 0.111	5.171AlaLys: 5.171 ± 0.079	12.363AlaLeu: 12.363 ± 0.17	3.699AlaMet: 3.699 ± 0.076	3.691AlaAsn: 3.691 ± 0.079	5.378AlaPro: 5.378 ± 0.078	4.368AlaGln: 4.368 ± 0.077	7.316AlaArg: 7.316 ± 0.11	6.36AlaSer: 6.36 ± 0.081	6.227AlaThr: 6.227 ± 0.106	7.911AlaVal: 7.911 ± 0.109	1.318AlaTrp: 1.318 ± 0.034	2.557AlaTyr: 2.557 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.036CysAla: 1.036 ± 0.038	0.1CysCys: 0.1 ± 0.01	0.596CysAsp: 0.596 ± 0.026	0.412CysGlu: 0.412 ± 0.022	0.343CysPhe: 0.343 ± 0.017	0.925CysGly: 0.925 ± 0.032	0.222CysHis: 0.222 ± 0.017	0.449CysIle: 0.449 ± 0.024	0.248CysLys: 0.248 ± 0.016	0.696CysLeu: 0.696 ± 0.027	0.152CysMet: 0.152 ± 0.012	0.27CysAsn: 0.27 ± 0.017	0.461CysPro: 0.461 ± 0.021	0.218CysGln: 0.218 ± 0.015	0.514CysArg: 0.514 ± 0.022	0.48CysSer: 0.48 ± 0.021	0.443CysThr: 0.443 ± 0.019	0.554CysVal: 0.554 ± 0.026	0.105CysTrp: 0.105 ± 0.01	0.198CysTyr: 0.198 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.12AspAla: 7.12 ± 0.106	0.491AspCys: 0.491 ± 0.025	3.256AspAsp: 3.256 ± 0.063	3.376AspGlu: 3.376 ± 0.066	2.38AspPhe: 2.38 ± 0.054	5.601AspGly: 5.601 ± 0.088	1.216AspHis: 1.216 ± 0.035	3.579AspIle: 3.579 ± 0.064	2.116AspLys: 2.116 ± 0.044	5.301AspLeu: 5.301 ± 0.072	1.535AspMet: 1.535 ± 0.041	1.748AspAsn: 1.748 ± 0.048	3.319AspPro: 3.319 ± 0.063	1.864AspGln: 1.864 ± 0.043	4.106AspArg: 4.106 ± 0.071	2.836AspSer: 2.836 ± 0.057	2.604AspThr: 2.604 ± 0.055	4.094AspVal: 4.094 ± 0.071	1.098AspTrp: 1.098 ± 0.032	1.639AspTyr: 1.639 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.951GluAla: 6.951 ± 0.1	0.357GluCys: 0.357 ± 0.018	2.75GluAsp: 2.75 ± 0.057	3.112GluGlu: 3.112 ± 0.068	1.907GluPhe: 1.907 ± 0.047	4.215GluGly: 4.215 ± 0.073	1.102GluHis: 1.102 ± 0.041	3.479GluIle: 3.479 ± 0.064	2.615GluLys: 2.615 ± 0.052	5.076GluLeu: 5.076 ± 0.077	1.571GluMet: 1.571 ± 0.041	1.939GluAsn: 1.939 ± 0.05	2.399GluPro: 2.399 ± 0.044	2.201GluGln: 2.201 ± 0.049	4.235GluArg: 4.235 ± 0.083	2.805GluSer: 2.805 ± 0.049	3.129GluThr: 3.129 ± 0.057	3.451GluVal: 3.451 ± 0.062	0.784GluTrp: 0.784 ± 0.028	1.233GluTyr: 1.233 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.839PheAla: 4.839 ± 0.082	0.374PheCys: 0.374 ± 0.019	2.845PheAsp: 2.845 ± 0.067	2.192PheGlu: 2.192 ± 0.049	1.504PhePhe: 1.504 ± 0.049	3.96PheGly: 3.96 ± 0.074	0.725PheHis: 0.725 ± 0.028	1.784PheIle: 1.784 ± 0.044	1.147PheLys: 1.147 ± 0.037	3.251PheLeu: 3.251 ± 0.067	0.847PheMet: 0.847 ± 0.033	1.341PheAsn: 1.341 ± 0.042	1.607PhePro: 1.607 ± 0.043	0.982PheGln: 0.982 ± 0.031	2.146PheArg: 2.146 ± 0.048	2.34PheSer: 2.34 ± 0.053	2.151PheThr: 2.151 ± 0.051	2.701PheVal: 2.701 ± 0.048	0.582PheTrp: 0.582 ± 0.028	0.947PheTyr: 0.947 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	8.932GlyAla: 8.932 ± 0.13	0.903GlyCys: 0.903 ± 0.036	4.616GlyAsp: 4.616 ± 0.071	4.648GlyGlu: 4.648 ± 0.083	3.722GlyPhe: 3.722 ± 0.066	7.822GlyGly: 7.822 ± 0.128	1.76GlyHis: 1.76 ± 0.045	4.887GlyIle: 4.887 ± 0.099	4.151GlyLys: 4.151 ± 0.07	8.227GlyLeu: 8.227 ± 0.089	2.274GlyMet: 2.274 ± 0.056	2.816GlyAsn: 2.816 ± 0.077	3.45GlyPro: 3.45 ± 0.057	3.061GlyGln: 3.061 ± 0.057	5.261GlyArg: 5.261 ± 0.08	5.093GlySer: 5.093 ± 0.095	4.947GlyThr: 4.947 ± 0.114	5.879GlyVal: 5.879 ± 0.084	1.506GlyTrp: 1.506 ± 0.037	2.503GlyTyr: 2.503 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.091HisAla: 2.091 ± 0.052	0.249HisCys: 0.249 ± 0.016	1.141HisAsp: 1.141 ± 0.035	0.96HisGlu: 0.96 ± 0.031	0.951HisPhe: 0.951 ± 0.031	1.759HisGly: 1.759 ± 0.051	0.589HisHis: 0.589 ± 0.029	1.209HisIle: 1.209 ± 0.044	0.648HisLys: 0.648 ± 0.026	1.835HisLeu: 1.835 ± 0.054	0.535HisMet: 0.535 ± 0.02	0.585HisAsn: 0.585 ± 0.026	1.249HisPro: 1.249 ± 0.041	0.613HisGln: 0.613 ± 0.021	1.227HisArg: 1.227 ± 0.037	1.027HisSer: 1.027 ± 0.031	0.6HisThr: 0.6 ± 0.026	1.424HisVal: 1.424 ± 0.038	0.366HisTrp: 0.366 ± 0.018	0.688HisTyr: 0.688 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	7.737IleAla: 7.737 ± 0.098	0.582IleCys: 0.582 ± 0.025	3.93IleAsp: 3.93 ± 0.063	3.677IleGlu: 3.677 ± 0.071	2.018IlePhe: 2.018 ± 0.05	5.285IleGly: 5.285 ± 0.087	0.954IleHis: 0.954 ± 0.033	2.918IleIle: 2.918 ± 0.066	1.787IleLys: 1.787 ± 0.046	4.682IleLeu: 4.682 ± 0.08	1.14IleMet: 1.14 ± 0.033	1.761IleAsn: 1.761 ± 0.049	2.544IlePro: 2.544 ± 0.052	1.336IleGln: 1.336 ± 0.037	3.316IleArg: 3.316 ± 0.06	3.588IleSer: 3.588 ± 0.065	2.886IleThr: 2.886 ± 0.065	4.21IleVal: 4.21 ± 0.067	0.821IleTrp: 0.821 ± 0.031	1.299IleTyr: 1.299 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	5.096LysAla: 5.096 ± 0.076	0.235LysCys: 0.235 ± 0.014	2.029LysAsp: 2.029 ± 0.048	1.819LysGlu: 1.819 ± 0.043	1.197LysPhe: 1.197 ± 0.034	3.275LysGly: 3.275 ± 0.065	0.669LysHis: 0.669 ± 0.025	2.216LysIle: 2.216 ± 0.051	1.698LysLys: 1.698 ± 0.05	3.942LysLeu: 3.942 ± 0.072	1.144LysMet: 1.144 ± 0.038	1.134LysAsn: 1.134 ± 0.033	2.314LysPro: 2.314 ± 0.052	1.145LysGln: 1.145 ± 0.038	2.538LysArg: 2.538 ± 0.052	2.364LysSer: 2.364 ± 0.058	2.106LysThr: 2.106 ± 0.042	2.651LysVal: 2.651 ± 0.048	0.592LysTrp: 0.592 ± 0.027	0.88LysTyr: 0.88 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	12.251LeuAla: 12.251 ± 0.138	0.773LeuCys: 0.773 ± 0.026	5.761LeuAsp: 5.761 ± 0.083	4.786LeuGlu: 4.786 ± 0.066	3.77LeuPhe: 3.77 ± 0.071	7.847LeuGly: 7.847 ± 0.103	1.786LeuHis: 1.786 ± 0.049	5.015LeuIle: 5.015 ± 0.089	3.632LeuLys: 3.632 ± 0.07	9.034LeuLeu: 9.034 ± 0.137	2.17LeuMet: 2.17 ± 0.051	2.963LeuAsn: 2.963 ± 0.062	5.051LeuPro: 5.051 ± 0.081	2.695LeuGln: 2.695 ± 0.055	5.892LeuArg: 5.892 ± 0.097	6.346LeuSer: 6.346 ± 0.091	5.392LeuThr: 5.392 ± 0.072	6.666LeuVal: 6.666 ± 0.093	1.23LeuTrp: 1.23 ± 0.039	2.005LeuTyr: 2.005 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	3.348MetAla: 3.348 ± 0.054	0.203MetCys: 0.203 ± 0.013	1.301MetAsp: 1.301 ± 0.033	1.178MetGlu: 1.178 ± 0.033	0.728MetPhe: 0.728 ± 0.028	2.0MetGly: 2.0 ± 0.052	0.527MetHis: 0.527 ± 0.027	1.403MetIle: 1.403 ± 0.038	1.132MetLys: 1.132 ± 0.035	2.704MetLeu: 2.704 ± 0.056	0.735MetMet: 0.735 ± 0.028	0.788MetAsn: 0.788 ± 0.033	1.509MetPro: 1.509 ± 0.041	0.864MetGln: 0.864 ± 0.028	1.78MetArg: 1.78 ± 0.044	1.555MetSer: 1.555 ± 0.038	1.842MetThr: 1.842 ± 0.046	1.685MetVal: 1.685 ± 0.043	0.258MetTrp: 0.258 ± 0.016	0.278MetTyr: 0.278 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.896AsnAla: 3.896 ± 0.085	0.305AsnCys: 0.305 ± 0.018	1.759AsnAsp: 1.759 ± 0.05	1.39AsnGlu: 1.39 ± 0.038	1.251AsnPhe: 1.251 ± 0.045	3.151AsnGly: 3.151 ± 0.083	0.555AsnHis: 0.555 ± 0.024	1.959AsnIle: 1.959 ± 0.054	0.969AsnLys: 0.969 ± 0.033	2.983AsnLeu: 2.983 ± 0.06	0.776AsnMet: 0.776 ± 0.027	1.108AsnAsn: 1.108 ± 0.049	2.077AsnPro: 2.077 ± 0.047	0.929AsnGln: 0.929 ± 0.029	2.066AsnArg: 2.066 ± 0.048	1.864AsnSer: 1.864 ± 0.056	1.311AsnThr: 1.311 ± 0.043	2.249AsnVal: 2.249 ± 0.062	0.567AsnTrp: 0.567 ± 0.025	0.878AsnTyr: 0.878 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	5.701ProAla: 5.701 ± 0.091	0.315ProCys: 0.315 ± 0.019	3.737ProAsp: 3.737 ± 0.075	3.465ProGlu: 3.465 ± 0.063	1.927ProPhe: 1.927 ± 0.051	3.954ProGly: 3.954 ± 0.063	1.08ProHis: 1.08 ± 0.034	2.435ProIle: 2.435 ± 0.048	2.032ProLys: 2.032 ± 0.052	4.623ProLeu: 4.623 ± 0.07	1.234ProMet: 1.234 ± 0.035	1.465ProAsn: 1.465 ± 0.04	2.305ProPro: 2.305 ± 0.076	1.698ProGln: 1.698 ± 0.043	2.372ProArg: 2.372 ± 0.051	2.755ProSer: 2.755 ± 0.054	2.42ProThr: 2.42 ± 0.051	4.256ProVal: 4.256 ± 0.058	0.634ProTrp: 0.634 ± 0.027	1.188ProTyr: 1.188 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.663GlnAla: 3.663 ± 0.064	0.281GlnCys: 0.281 ± 0.018	1.474GlnAsp: 1.474 ± 0.035	1.466GlnGlu: 1.466 ± 0.037	1.292GlnPhe: 1.292 ± 0.04	2.445GlnGly: 2.445 ± 0.047	0.63GlnHis: 0.63 ± 0.025	2.182GlnIle: 2.182 ± 0.047	1.347GlnLys: 1.347 ± 0.037	3.201GlnLeu: 3.201 ± 0.069	0.98GlnMet: 0.98 ± 0.027	1.129GlnAsn: 1.129 ± 0.037	1.684GlnPro: 1.684 ± 0.045	1.23GlnGln: 1.23 ± 0.037	2.189GlnArg: 2.189 ± 0.041	2.104GlnSer: 2.104 ± 0.05	1.751GlnThr: 1.751 ± 0.043	2.108GlnVal: 2.108 ± 0.044	0.511GlnTrp: 0.511 ± 0.024	0.732GlnTyr: 0.732 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	6.827ArgAla: 6.827 ± 0.095	0.437ArgCys: 0.437 ± 0.02	3.701ArgAsp: 3.701 ± 0.055	3.487ArgGlu: 3.487 ± 0.065	2.842ArgPhe: 2.842 ± 0.066	4.235ArgGly: 4.235 ± 0.066	1.434ArgHis: 1.434 ± 0.039	3.93ArgIle: 3.93 ± 0.069	2.55ArgLys: 2.55 ± 0.05	6.737ArgLeu: 6.737 ± 0.093	1.774ArgMet: 1.774 ± 0.044	2.152ArgAsn: 2.152 ± 0.049	3.024ArgPro: 3.024 ± 0.061	2.359ArgGln: 2.359 ± 0.053	4.067ArgArg: 4.067 ± 0.076	3.463ArgSer: 3.463 ± 0.062	3.141ArgThr: 3.141 ± 0.056	3.98ArgVal: 3.98 ± 0.067	0.954ArgTrp: 0.954 ± 0.032	1.834ArgTyr: 1.834 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.693SerAla: 6.693 ± 0.084	0.49SerCys: 0.49 ± 0.023	3.508SerAsp: 3.508 ± 0.062	3.153SerGlu: 3.153 ± 0.054	2.476SerPhe: 2.476 ± 0.052	5.909SerGly: 5.909 ± 0.094	1.057SerHis: 1.057 ± 0.039	3.314SerIle: 3.314 ± 0.063	2.088SerLys: 2.088 ± 0.051	5.366SerLeu: 5.366 ± 0.087	1.35SerMet: 1.35 ± 0.04	1.919SerAsn: 1.919 ± 0.048	2.787SerPro: 2.787 ± 0.061	1.658SerGln: 1.658 ± 0.047	3.309SerArg: 3.309 ± 0.065	3.177SerSer: 3.177 ± 0.064	2.978SerThr: 2.978 ± 0.061	4.137SerVal: 4.137 ± 0.093	0.856SerTrp: 0.856 ± 0.033	1.507SerTyr: 1.507 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	6.272ThrAla: 6.272 ± 0.097	0.423ThrCys: 0.423 ± 0.021	3.108ThrAsp: 3.108 ± 0.063	2.641ThrGlu: 2.641 ± 0.056	1.87ThrPhe: 1.87 ± 0.05	5.388ThrGly: 5.388 ± 0.109	1.015ThrHis: 1.015 ± 0.029	3.16ThrIle: 3.16 ± 0.07	1.769ThrLys: 1.769 ± 0.05	5.392ThrLeu: 5.392 ± 0.084	1.207ThrMet: 1.207 ± 0.033	1.631ThrAsn: 1.631 ± 0.054	3.084ThrPro: 3.084 ± 0.055	1.667ThrGln: 1.667 ± 0.045	2.986ThrArg: 2.986 ± 0.052	3.004ThrSer: 3.004 ± 0.061	2.871ThrThr: 2.871 ± 0.08	3.992ThrVal: 3.992 ± 0.076	0.567ThrTrp: 0.567 ± 0.025	1.219ThrTyr: 1.219 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	8.583ValAla: 8.583 ± 0.134	0.519ValCys: 0.519 ± 0.024	4.395ValAsp: 4.395 ± 0.065	4.427ValGlu: 4.427 ± 0.072	2.159ValPhe: 2.159 ± 0.045	5.426ValGly: 5.426 ± 0.084	1.279ValHis: 1.279 ± 0.036	3.844ValIle: 3.844 ± 0.066	2.613ValLys: 2.613 ± 0.054	5.777ValLeu: 5.777 ± 0.086	1.745ValMet: 1.745 ± 0.042	2.336ValAsn: 2.336 ± 0.072	3.538ValPro: 3.538 ± 0.065	2.133ValGln: 2.133 ± 0.043	4.627ValArg: 4.627 ± 0.07	4.24ValSer: 4.24 ± 0.07	4.564ValThr: 4.564 ± 0.073	4.955ValVal: 4.955 ± 0.09	0.818ValTrp: 0.818 ± 0.029	1.395ValTyr: 1.395 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.317TrpAla: 1.317 ± 0.04	0.122TrpCys: 0.122 ± 0.01	0.767TrpAsp: 0.767 ± 0.026	0.615TrpGlu: 0.615 ± 0.027	0.577TrpPhe: 0.577 ± 0.029	1.032TrpGly: 1.032 ± 0.036	0.386TrpHis: 0.386 ± 0.019	0.76TrpIle: 0.76 ± 0.03	0.584TrpLys: 0.584 ± 0.023	1.658TrpLeu: 1.658 ± 0.046	0.413TrpMet: 0.413 ± 0.018	0.489TrpAsn: 0.489 ± 0.022	0.686TrpPro: 0.686 ± 0.028	0.607TrpGln: 0.607 ± 0.025	1.151TrpArg: 1.151 ± 0.038	0.882TrpSer: 0.882 ± 0.032	0.8TrpThr: 0.8 ± 0.029	0.85TrpVal: 0.85 ± 0.034	0.242TrpTrp: 0.242 ± 0.018	0.308TrpTyr: 0.308 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.64TyrAla: 2.64 ± 0.05	0.262TyrCys: 0.262 ± 0.017	1.624TyrAsp: 1.624 ± 0.045	1.249TyrGlu: 1.249 ± 0.035	1.027TyrPhe: 1.027 ± 0.035	2.264TyrGly: 2.264 ± 0.054	0.537TyrHis: 0.537 ± 0.023	1.066TyrIle: 1.066 ± 0.032	0.748TyrLys: 0.748 ± 0.027	2.216TyrLeu: 2.216 ± 0.047	0.532TyrMet: 0.532 ± 0.023	0.775TyrAsn: 0.775 ± 0.03	1.127TyrPro: 1.127 ± 0.035	0.773TyrGln: 0.773 ± 0.029	1.831TyrArg: 1.831 ± 0.041	1.451TyrSer: 1.451 ± 0.04	1.107TyrThr: 1.107 ± 0.036	1.617TyrVal: 1.617 ± 0.042	0.44TyrTrp: 0.44 ± 0.023	0.675TyrTyr: 0.675 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3099 proteins (1006683 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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