Amino acid dipepetide frequency for Ethiopian tobacco bushy top virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.834AlaAla: 4.834 ± 3.242
0.0AlaCys: 0.0 ± 0.0
4.23AlaAsp: 4.23 ± 0.572
5.438AlaGlu: 5.438 ± 3.21
1.813AlaPhe: 1.813 ± 0.73
5.438AlaGly: 5.438 ± 1.178
1.813AlaHis: 1.813 ± 0.566
4.834AlaIle: 4.834 ± 1.213
2.417AlaLys: 2.417 ± 1.333
7.855AlaLeu: 7.855 ± 1.863
2.417AlaMet: 2.417 ± 0.532
2.417AlaAsn: 2.417 ± 1.106
9.063AlaPro: 9.063 ± 1.416
3.625AlaGln: 3.625 ± 1.044
6.042AlaArg: 6.042 ± 0.562
4.834AlaSer: 4.834 ± 1.184
3.021AlaThr: 3.021 ± 2.996
5.438AlaVal: 5.438 ± 1.686
3.021AlaTrp: 3.021 ± 1.199
0.604AlaTyr: 0.604 ± 0.73
0.604AlaXaa: 0.604 ± 0.333
Cys
0.604CysAla: 0.604 ± 0.73
0.604CysCys: 0.604 ± 0.333
1.208CysAsp: 1.208 ± 0.553
0.0CysGlu: 0.0 ± 0.0
1.813CysPhe: 1.813 ± 0.769
4.23CysGly: 4.23 ± 0.986
0.0CysHis: 0.0 ± 0.0
0.604CysIle: 0.604 ± 0.333
0.0CysLys: 0.0 ± 0.0
1.208CysLeu: 1.208 ± 1.005
0.604CysMet: 0.604 ± 0.322
1.813CysAsn: 1.813 ± 0.72
1.208CysPro: 1.208 ± 0.553
0.604CysGln: 0.604 ± 0.333
3.021CysArg: 3.021 ± 1.21
0.604CysSer: 0.604 ± 0.73
0.604CysThr: 0.604 ± 0.333
2.417CysVal: 2.417 ± 0.942
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.042AspAla: 6.042 ± 0.515
2.417AspCys: 2.417 ± 0.737
3.625AspAsp: 3.625 ± 0.882
1.208AspGlu: 1.208 ± 0.666
1.208AspPhe: 1.208 ± 0.666
4.834AspGly: 4.834 ± 1.087
1.208AspHis: 1.208 ± 0.553
1.813AspIle: 1.813 ± 0.684
1.813AspLys: 1.813 ± 0.564
3.021AspLeu: 3.021 ± 0.391
0.604AspMet: 0.604 ± 0.333
1.813AspAsn: 1.813 ± 0.564
3.021AspPro: 3.021 ± 0.636
3.625AspGln: 3.625 ± 0.882
4.23AspArg: 4.23 ± 1.006
1.813AspSer: 1.813 ± 1.29
1.813AspThr: 1.813 ± 0.769
1.208AspVal: 1.208 ± 0.561
0.0AspTrp: 0.0 ± 0.0
3.021AspTyr: 3.021 ± 1.199
0.0AspXaa: 0.0 ± 0.0
Glu
0.604GluAla: 0.604 ± 0.699
1.813GluCys: 1.813 ± 0.564
3.625GluAsp: 3.625 ± 0.999
2.417GluGlu: 2.417 ± 1.106
0.604GluPhe: 0.604 ± 0.333
4.834GluGly: 4.834 ± 0.482
1.208GluHis: 1.208 ± 0.561
2.417GluIle: 2.417 ± 1.122
1.813GluLys: 1.813 ± 0.73
5.438GluLeu: 5.438 ± 1.492
0.604GluMet: 0.604 ± 0.699
3.625GluAsn: 3.625 ± 0.882
0.604GluPro: 0.604 ± 0.333
0.604GluGln: 0.604 ± 0.333
3.625GluArg: 3.625 ± 0.826
4.23GluSer: 4.23 ± 0.289
1.813GluThr: 1.813 ± 0.73
10.272GluVal: 10.272 ± 1.675
1.208GluTrp: 1.208 ± 0.553
1.208GluTyr: 1.208 ± 0.553
3.021GluXaa: 3.021 ± 1.199
Phe
2.417PheAla: 2.417 ± 0.532
0.604PheCys: 0.604 ± 0.333
4.23PheAsp: 4.23 ± 1.598
0.604PheGlu: 0.604 ± 0.333
0.0PhePhe: 0.0 ± 0.0
3.021PheGly: 3.021 ± 0.636
0.0PheHis: 0.0 ± 0.0
1.208PheIle: 1.208 ± 0.632
0.0PheLys: 0.0 ± 0.0
1.208PheLeu: 1.208 ± 0.666
0.0PheMet: 0.0 ± 0.481
2.417PheAsn: 2.417 ± 1.333
0.604PhePro: 0.604 ± 0.699
1.208PheGln: 1.208 ± 0.553
1.813PheArg: 1.813 ± 0.73
1.208PheSer: 1.208 ± 0.632
3.021PheThr: 3.021 ± 1.908
1.208PheVal: 1.208 ± 0.666
0.0PheTrp: 0.0 ± 0.0
1.208PheTyr: 1.208 ± 0.632
0.0PheXaa: 0.0 ± 0.0
Gly
7.855GlyAla: 7.855 ± 1.293
1.208GlyCys: 1.208 ± 0.561
4.23GlyAsp: 4.23 ± 2.093
6.042GlyGlu: 6.042 ± 2.238
1.813GlyPhe: 1.813 ± 1.0
5.438GlyGly: 5.438 ± 1.651
4.834GlyHis: 4.834 ± 1.503
2.417GlyIle: 2.417 ± 0.737
1.813GlyLys: 1.813 ± 0.564
9.063GlyLeu: 9.063 ± 1.399
1.813GlyMet: 1.813 ± 0.73
2.417GlyAsn: 2.417 ± 0.532
4.834GlyPro: 4.834 ± 0.795
1.208GlyGln: 1.208 ± 1.005
4.834GlyArg: 4.834 ± 3.961
4.23GlySer: 4.23 ± 0.289
0.0GlyThr: 0.0 ± 0.0
8.459GlyVal: 8.459 ± 0.416
1.208GlyTrp: 1.208 ± 0.553
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.604HisCys: 0.604 ± 0.333
2.417HisAsp: 2.417 ± 0.532
1.208HisGlu: 1.208 ± 0.666
0.0HisPhe: 0.0 ± 0.0
1.813HisGly: 1.813 ± 0.684
1.208HisHis: 1.208 ± 0.553
1.813HisIle: 1.813 ± 0.73
0.0HisLys: 0.0 ± 0.0
1.813HisLeu: 1.813 ± 1.0
2.417HisMet: 2.417 ± 1.106
1.813HisAsn: 1.813 ± 0.73
0.604HisPro: 0.604 ± 0.73
0.0HisGln: 0.0 ± 0.0
3.625HisArg: 3.625 ± 2.03
1.208HisSer: 1.208 ± 1.461
1.208HisThr: 1.208 ± 1.005
1.208HisVal: 1.208 ± 0.632
0.0HisTrp: 0.0 ± 0.0
1.208HisTyr: 1.208 ± 0.666
0.0HisXaa: 0.0 ± 0.0
Ile
3.021IleAla: 3.021 ± 1.037
0.604IleCys: 0.604 ± 0.699
1.208IleAsp: 1.208 ± 0.561
1.813IleGlu: 1.813 ± 1.29
0.604IlePhe: 0.604 ± 0.333
1.208IleGly: 1.208 ± 0.666
2.417IleHis: 2.417 ± 1.36
1.208IleIle: 1.208 ± 0.553
3.021IleLys: 3.021 ± 1.208
3.021IleLeu: 3.021 ± 1.199
1.208IleMet: 1.208 ± 0.632
1.813IleAsn: 1.813 ± 0.564
4.23IlePro: 4.23 ± 1.006
0.604IleGln: 0.604 ± 0.333
2.417IleArg: 2.417 ± 0.532
3.021IleSer: 3.021 ± 0.648
4.23IleThr: 4.23 ± 1.737
1.813IleVal: 1.813 ± 0.73
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.021LysAla: 3.021 ± 0.683
0.0LysCys: 0.0 ± 0.0
3.021LysAsp: 3.021 ± 0.683
1.208LysGlu: 1.208 ± 1.398
1.813LysPhe: 1.813 ± 0.73
1.813LysGly: 1.813 ± 0.564
1.208LysHis: 1.208 ± 0.561
0.0LysIle: 0.0 ± 0.0
1.208LysLys: 1.208 ± 0.666
2.417LysLeu: 2.417 ± 0.923
0.604LysMet: 0.604 ± 0.333
1.813LysAsn: 1.813 ± 0.564
4.23LysPro: 4.23 ± 1.27
1.813LysGln: 1.813 ± 1.259
1.208LysArg: 1.208 ± 0.666
2.417LysSer: 2.417 ± 1.341
1.208LysThr: 1.208 ± 0.632
3.625LysVal: 3.625 ± 1.128
2.417LysTrp: 2.417 ± 1.122
1.208LysTyr: 1.208 ± 0.666
0.0LysXaa: 0.0 ± 0.0
Leu
6.647LeuAla: 6.647 ± 0.644
2.417LeuCys: 2.417 ± 0.592
7.855LeuAsp: 7.855 ± 0.938
3.021LeuGlu: 3.021 ± 0.683
1.208LeuPhe: 1.208 ± 1.005
7.251LeuGly: 7.251 ± 1.284
1.208LeuHis: 1.208 ± 1.005
3.021LeuIle: 3.021 ± 1.199
2.417LeuLys: 2.417 ± 0.923
10.272LeuLeu: 10.272 ± 1.922
2.417LeuMet: 2.417 ± 1.264
3.625LeuAsn: 3.625 ± 1.029
7.251LeuPro: 7.251 ± 1.764
4.23LeuGln: 4.23 ± 0.572
8.459LeuArg: 8.459 ± 0.416
6.647LeuSer: 6.647 ± 0.58
2.417LeuThr: 2.417 ± 1.264
4.23LeuVal: 4.23 ± 0.572
1.208LeuTrp: 1.208 ± 0.666
1.813LeuTyr: 1.813 ± 0.73
1.208LeuXaa: 1.208 ± 0.553
Met
3.625MetAla: 3.625 ± 0.802
0.0MetCys: 0.0 ± 0.0
1.813MetAsp: 1.813 ± 1.0
2.417MetGlu: 2.417 ± 1.106
1.813MetPhe: 1.813 ± 0.684
1.208MetGly: 1.208 ± 0.632
0.0MetHis: 0.0 ± 0.0
1.208MetIle: 1.208 ± 0.553
0.604MetLys: 0.604 ± 0.333
1.208MetLeu: 1.208 ± 0.666
1.208MetMet: 1.208 ± 0.553
0.0MetAsn: 0.0 ± 0.0
1.208MetPro: 1.208 ± 0.632
0.604MetGln: 0.604 ± 0.333
0.0MetArg: 0.0 ± 0.0
1.813MetSer: 1.813 ± 1.29
2.417MetThr: 2.417 ± 0.592
1.813MetVal: 1.813 ± 0.73
1.813MetTrp: 1.813 ± 0.566
0.604MetTyr: 0.604 ± 0.333
0.0MetXaa: 0.0 ± 0.0
Asn
4.23AsnAla: 4.23 ± 1.27
1.813AsnCys: 1.813 ± 0.73
0.0AsnAsp: 0.0 ± 0.0
3.625AsnGlu: 3.625 ± 1.368
1.813AsnPhe: 1.813 ± 0.684
4.23AsnGly: 4.23 ± 0.766
1.208AsnHis: 1.208 ± 0.666
0.604AsnIle: 0.604 ± 0.73
1.208AsnLys: 1.208 ± 1.461
3.625AsnLeu: 3.625 ± 0.934
0.0AsnMet: 0.0 ± 0.0
1.813AsnAsn: 1.813 ± 1.0
1.813AsnPro: 1.813 ± 0.564
0.0AsnGln: 0.0 ± 0.0
6.042AsnArg: 6.042 ± 2.112
3.625AsnSer: 3.625 ± 1.009
3.625AsnThr: 3.625 ± 0.802
1.813AsnVal: 1.813 ± 1.259
2.417AsnTrp: 2.417 ± 0.923
0.604AsnTyr: 0.604 ± 0.699
0.0AsnXaa: 0.0 ± 0.0
Pro
12.689ProAla: 12.689 ± 3.152
0.604ProCys: 0.604 ± 0.333
1.208ProAsp: 1.208 ± 0.632
1.813ProGlu: 1.813 ± 0.564
0.604ProPhe: 0.604 ± 0.699
4.23ProGly: 4.23 ± 0.572
2.417ProHis: 2.417 ± 1.264
1.813ProIle: 1.813 ± 1.29
4.834ProLys: 4.834 ± 3.462
4.23ProLeu: 4.23 ± 1.761
0.604ProMet: 0.604 ± 0.333
2.417ProAsn: 2.417 ± 1.341
10.272ProPro: 10.272 ± 1.967
4.23ProGln: 4.23 ± 1.667
7.855ProArg: 7.855 ± 0.843
6.042ProSer: 6.042 ± 1.749
4.834ProThr: 4.834 ± 0.795
4.834ProVal: 4.834 ± 1.068
0.604ProTrp: 0.604 ± 0.333
3.625ProTyr: 3.625 ± 0.882
1.208ProXaa: 1.208 ± 0.553
Gln
3.625GlnAla: 3.625 ± 0.882
0.604GlnCys: 0.604 ± 0.333
0.0GlnAsp: 0.0 ± 0.0
3.625GlnGlu: 3.625 ± 0.882
0.604GlnPhe: 0.604 ± 0.333
4.834GlnGly: 4.834 ± 1.898
0.604GlnHis: 0.604 ± 0.333
1.813GlnIle: 1.813 ± 0.566
0.604GlnLys: 0.604 ± 0.699
3.625GlnLeu: 3.625 ± 1.821
1.208GlnMet: 1.208 ± 0.553
1.813GlnAsn: 1.813 ± 0.72
4.834GlnPro: 4.834 ± 0.795
0.604GlnGln: 0.604 ± 0.333
6.042GlnArg: 6.042 ± 2.092
1.813GlnSer: 1.813 ± 0.73
1.208GlnThr: 1.208 ± 0.632
1.208GlnVal: 1.208 ± 1.461
0.0GlnTrp: 0.0 ± 0.0
0.604GlnTyr: 0.604 ± 0.333
0.0GlnXaa: 0.0 ± 0.0
Arg
6.042ArgAla: 6.042 ± 1.546
4.23ArgCys: 4.23 ± 0.572
3.021ArgAsp: 3.021 ± 1.199
4.834ArgGlu: 4.834 ± 1.184
3.021ArgPhe: 3.021 ± 1.324
4.834ArgGly: 4.834 ± 1.874
1.813ArgHis: 1.813 ± 1.0
2.417ArgIle: 2.417 ± 1.264
2.417ArgLys: 2.417 ± 1.36
7.251ArgLeu: 7.251 ± 0.824
3.625ArgMet: 3.625 ± 0.977
2.417ArgAsn: 2.417 ± 0.721
10.272ArgPro: 10.272 ± 1.46
2.417ArgGln: 2.417 ± 1.981
7.251ArgArg: 7.251 ± 4.06
6.647ArgSer: 6.647 ± 2.375
0.604ArgThr: 0.604 ± 0.73
9.063ArgVal: 9.063 ± 3.153
1.813ArgTrp: 1.813 ± 1.259
3.625ArgTyr: 3.625 ± 0.826
0.0ArgXaa: 0.0 ± 0.0
Ser
4.23SerAla: 4.23 ± 1.275
1.813SerCys: 1.813 ± 0.566
2.417SerAsp: 2.417 ± 0.592
3.625SerGlu: 3.625 ± 0.085
1.208SerPhe: 1.208 ± 0.666
4.834SerGly: 4.834 ± 2.72
1.208SerHis: 1.208 ± 0.632
1.813SerIle: 1.813 ± 0.73
1.813SerLys: 1.813 ± 0.73
8.459SerLeu: 8.459 ± 1.043
2.417SerMet: 2.417 ± 0.592
1.813SerAsn: 1.813 ± 1.259
6.647SerPro: 6.647 ± 1.117
4.834SerGln: 4.834 ± 0.482
6.647SerArg: 6.647 ± 2.663
3.625SerSer: 3.625 ± 1.012
1.813SerThr: 1.813 ± 0.769
3.021SerVal: 3.021 ± 1.203
0.0SerTrp: 0.0 ± 0.0
1.813SerTyr: 1.813 ± 0.73
0.0SerXaa: 0.0 ± 0.0
Thr
4.23ThrAla: 4.23 ± 0.784
0.604ThrCys: 0.604 ± 0.73
1.813ThrAsp: 1.813 ± 0.769
1.208ThrGlu: 1.208 ± 0.553
0.604ThrPhe: 0.604 ± 0.333
4.23ThrGly: 4.23 ± 0.766
0.604ThrHis: 0.604 ± 0.333
1.208ThrIle: 1.208 ± 0.561
1.208ThrLys: 1.208 ± 1.005
4.23ThrLeu: 4.23 ± 0.572
0.604ThrMet: 0.604 ± 0.333
3.625ThrAsn: 3.625 ± 1.012
6.042ThrPro: 6.042 ± 2.043
3.625ThrGln: 3.625 ± 1.859
3.021ThrArg: 3.021 ± 1.21
2.417ThrSer: 2.417 ± 1.358
1.813ThrThr: 1.813 ± 0.72
1.813ThrVal: 1.813 ± 0.73
1.208ThrTrp: 1.208 ± 0.553
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.834ValAla: 4.834 ± 0.601
0.604ValCys: 0.604 ± 0.333
2.417ValAsp: 2.417 ± 0.737
6.042ValGlu: 6.042 ± 1.747
4.23ValPhe: 4.23 ± 1.124
2.417ValGly: 2.417 ± 0.942
1.208ValHis: 1.208 ± 0.561
3.021ValIle: 3.021 ± 1.208
6.647ValLys: 6.647 ± 2.076
6.647ValLeu: 6.647 ± 0.457
1.208ValMet: 1.208 ± 0.553
4.834ValAsn: 4.834 ± 0.618
1.813ValPro: 1.813 ± 1.612
2.417ValGln: 2.417 ± 1.341
4.23ValArg: 4.23 ± 1.59
4.834ValSer: 4.834 ± 0.618
3.625ValThr: 3.625 ± 0.965
3.625ValVal: 3.625 ± 2.581
1.813ValTrp: 1.813 ± 0.769
3.021ValTyr: 3.021 ± 1.075
0.0ValXaa: 0.0 ± 0.0
Trp
0.604TrpAla: 0.604 ± 0.73
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.604TrpGlu: 0.604 ± 0.333
1.208TrpPhe: 1.208 ± 0.553
1.208TrpGly: 1.208 ± 0.553
0.0TrpHis: 0.0 ± 0.0
0.604TrpIle: 0.604 ± 0.699
1.208TrpLys: 1.208 ± 0.666
1.813TrpLeu: 1.813 ± 0.684
1.208TrpMet: 1.208 ± 0.499
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
2.417TrpGln: 2.417 ± 0.532
3.625TrpArg: 3.625 ± 1.012
0.0TrpSer: 0.0 ± 0.0
0.604TrpThr: 0.604 ± 0.333
1.813TrpVal: 1.813 ± 0.72
0.0TrpTrp: 0.0 ± 0.0
3.021TrpTyr: 3.021 ± 1.199
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.604TyrAla: 0.604 ± 0.333
0.604TyrCys: 0.604 ± 0.73
0.0TyrAsp: 0.0 ± 0.0
1.208TyrGlu: 1.208 ± 0.553
0.604TyrPhe: 0.604 ± 0.333
1.813TyrGly: 1.813 ± 0.566
0.0TyrHis: 0.0 ± 0.0
3.625TyrIle: 3.625 ± 0.882
1.208TyrLys: 1.208 ± 0.666
2.417TyrLeu: 2.417 ± 0.532
0.0TyrMet: 0.0 ± 0.0
1.813TyrAsn: 1.813 ± 0.564
1.813TyrPro: 1.813 ± 0.769
0.604TyrGln: 0.604 ± 0.333
3.021TyrArg: 3.021 ± 1.208
3.021TyrSer: 3.021 ± 0.683
4.23TyrThr: 4.23 ± 1.086
0.604TyrVal: 0.604 ± 0.333
0.0TyrTrp: 0.0 ± 0.0
0.604TyrTyr: 0.604 ± 0.333
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
3.625XaaGlu: 3.625 ± 1.659
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.604XaaPro: 0.604 ± 0.333
0.0XaaGln: 0.0 ± 0.0
0.604XaaArg: 0.604 ± 0.333
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
1.208XaaTrp: 1.208 ± 0.553
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1656 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski