Amino acid dipepetide frequency for Hubei sobemo-like virus 23

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.064AlaAla: 2.064 ± 1.306
0.0AlaCys: 0.0 ± 0.0
3.096AlaAsp: 3.096 ± 1.959
5.16AlaGlu: 5.16 ± 1.37
2.064AlaPhe: 2.064 ± 1.784
4.128AlaGly: 4.128 ± 0.478
0.0AlaHis: 0.0 ± 0.0
3.096AlaIle: 3.096 ± 0.414
3.096AlaLys: 3.096 ± 0.414
4.128AlaLeu: 4.128 ± 0.478
2.064AlaMet: 2.064 ± 1.306
3.096AlaAsn: 3.096 ± 0.414
2.064AlaPro: 2.064 ± 1.306
1.032AlaGln: 1.032 ± 0.892
2.064AlaArg: 2.064 ± 0.239
3.096AlaSer: 3.096 ± 0.414
3.096AlaThr: 3.096 ± 1.959
2.064AlaVal: 2.064 ± 1.306
4.128AlaTrp: 4.128 ± 1.067
4.128AlaTyr: 4.128 ± 2.612
0.0AlaXaa: 0.0 ± 0.0
Cys
1.032CysAla: 1.032 ± 0.653
0.0CysCys: 0.0 ± 0.0
1.032CysAsp: 1.032 ± 0.892
1.032CysGlu: 1.032 ± 0.653
0.0CysPhe: 0.0 ± 0.0
2.064CysGly: 2.064 ± 1.306
1.032CysHis: 1.032 ± 0.892
0.0CysIle: 0.0 ± 0.0
1.032CysLys: 1.032 ± 0.653
1.032CysLeu: 1.032 ± 0.892
1.032CysMet: 1.032 ± 0.653
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.032CysArg: 1.032 ± 0.892
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.064CysVal: 2.064 ± 1.784
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.192AspAla: 6.192 ± 0.717
0.0AspCys: 0.0 ± 0.0
6.192AspAsp: 6.192 ± 0.717
3.096AspGlu: 3.096 ± 1.959
8.256AspPhe: 8.256 ± 0.588
4.128AspGly: 4.128 ± 2.023
3.096AspHis: 3.096 ± 0.414
4.128AspIle: 4.128 ± 0.478
2.064AspLys: 2.064 ± 0.239
4.128AspLeu: 4.128 ± 0.478
3.096AspMet: 3.096 ± 1.131
2.064AspAsn: 2.064 ± 0.239
3.096AspPro: 3.096 ± 1.131
2.064AspGln: 2.064 ± 1.784
1.032AspArg: 1.032 ± 0.653
1.032AspSer: 1.032 ± 0.653
3.096AspThr: 3.096 ± 0.414
4.128AspVal: 4.128 ± 2.612
1.032AspTrp: 1.032 ± 0.892
4.128AspTyr: 4.128 ± 1.067
0.0AspXaa: 0.0 ± 0.0
Glu
2.064GluAla: 2.064 ± 1.306
2.064GluCys: 2.064 ± 0.239
3.096GluAsp: 3.096 ± 1.131
3.096GluGlu: 3.096 ± 0.414
7.224GluPhe: 7.224 ± 1.48
6.192GluGly: 6.192 ± 0.828
0.0GluHis: 0.0 ± 0.0
2.064GluIle: 2.064 ± 0.239
2.064GluLys: 2.064 ± 0.239
6.192GluLeu: 6.192 ± 3.808
1.032GluMet: 1.032 ± 0.564
2.064GluAsn: 2.064 ± 0.239
3.096GluPro: 3.096 ± 0.414
2.064GluGln: 2.064 ± 0.239
3.096GluArg: 3.096 ± 1.959
3.096GluSer: 3.096 ± 1.959
0.0GluThr: 0.0 ± 0.0
1.032GluVal: 1.032 ± 0.653
0.0GluTrp: 0.0 ± 0.0
2.064GluTyr: 2.064 ± 1.306
0.0GluXaa: 0.0 ± 0.0
Phe
4.128PheAla: 4.128 ± 1.067
1.032PheCys: 1.032 ± 0.653
4.128PheAsp: 4.128 ± 2.612
2.064PheGlu: 2.064 ± 0.239
0.0PhePhe: 0.0 ± 0.0
4.128PheGly: 4.128 ± 2.023
0.0PheHis: 0.0 ± 0.0
6.192PheIle: 6.192 ± 0.717
5.16PheLys: 5.16 ± 1.37
3.096PheLeu: 3.096 ± 0.414
5.16PheMet: 5.16 ± 0.175
3.096PheAsn: 3.096 ± 2.676
1.032PhePro: 1.032 ± 0.653
0.0PheGln: 0.0 ± 0.0
2.064PheArg: 2.064 ± 0.239
9.288PheSer: 9.288 ± 0.304
2.064PheThr: 2.064 ± 0.239
4.128PheVal: 4.128 ± 1.067
1.032PheTrp: 1.032 ± 0.892
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.096GlyAla: 3.096 ± 1.959
1.032GlyCys: 1.032 ± 0.892
5.16GlyAsp: 5.16 ± 1.37
5.16GlyGlu: 5.16 ± 1.72
2.064GlyPhe: 2.064 ± 1.306
6.192GlyGly: 6.192 ± 5.353
3.096GlyHis: 3.096 ± 1.959
2.064GlyIle: 2.064 ± 1.306
5.16GlyLys: 5.16 ± 1.72
5.16GlyLeu: 5.16 ± 2.915
3.096GlyMet: 3.096 ± 1.131
2.064GlyAsn: 2.064 ± 1.306
2.064GlyPro: 2.064 ± 0.239
2.064GlyGln: 2.064 ± 0.239
3.096GlyArg: 3.096 ± 1.959
3.096GlySer: 3.096 ± 0.414
5.16GlyThr: 5.16 ± 3.265
6.192GlyVal: 6.192 ± 2.263
2.064GlyTrp: 2.064 ± 1.784
5.16GlyTyr: 5.16 ± 0.175
0.0GlyXaa: 0.0 ± 0.0
His
2.064HisAla: 2.064 ± 1.784
1.032HisCys: 1.032 ± 0.653
0.0HisAsp: 0.0 ± 0.0
1.032HisGlu: 1.032 ± 0.653
1.032HisPhe: 1.032 ± 0.653
1.032HisGly: 1.032 ± 0.653
0.0HisHis: 0.0 ± 0.0
2.064HisIle: 2.064 ± 1.306
0.0HisLys: 0.0 ± 0.0
1.032HisLeu: 1.032 ± 0.892
1.032HisMet: 1.032 ± 0.892
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.032HisGln: 1.032 ± 0.892
3.096HisArg: 3.096 ± 0.414
1.032HisSer: 1.032 ± 0.653
0.0HisThr: 0.0 ± 0.0
4.128HisVal: 4.128 ± 0.478
0.0HisTrp: 0.0 ± 0.0
1.032HisTyr: 1.032 ± 0.892
0.0HisXaa: 0.0 ± 0.0
Ile
6.192IleAla: 6.192 ± 2.263
2.064IleCys: 2.064 ± 0.239
5.16IleAsp: 5.16 ± 0.175
2.064IleGlu: 2.064 ± 1.784
4.128IlePhe: 4.128 ± 2.023
3.096IleGly: 3.096 ± 0.414
1.032IleHis: 1.032 ± 0.653
4.128IleIle: 4.128 ± 2.023
9.288IleLys: 9.288 ± 1.241
8.256IleLeu: 8.256 ± 0.588
0.0IleMet: 0.0 ± 0.0
1.032IleAsn: 1.032 ± 0.653
4.128IlePro: 4.128 ± 2.023
0.0IleGln: 0.0 ± 0.0
6.192IleArg: 6.192 ± 0.828
2.064IleSer: 2.064 ± 0.239
3.096IleThr: 3.096 ± 1.131
7.224IleVal: 7.224 ± 3.025
2.064IleTrp: 2.064 ± 0.239
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.128LysAla: 4.128 ± 2.612
2.064LysCys: 2.064 ± 1.784
5.16LysAsp: 5.16 ± 1.72
3.096LysGlu: 3.096 ± 0.414
4.128LysPhe: 4.128 ± 3.568
5.16LysGly: 5.16 ± 1.72
2.064LysHis: 2.064 ± 0.239
7.224LysIle: 7.224 ± 1.48
7.224LysLys: 7.224 ± 3.025
4.128LysLeu: 4.128 ± 1.067
3.096LysMet: 3.096 ± 0.414
1.032LysAsn: 1.032 ± 0.653
6.192LysPro: 6.192 ± 2.373
5.16LysGln: 5.16 ± 2.915
1.032LysArg: 1.032 ± 0.892
8.256LysSer: 8.256 ± 0.588
3.096LysThr: 3.096 ± 0.414
5.16LysVal: 5.16 ± 1.72
0.0LysTrp: 0.0 ± 0.0
1.032LysTyr: 1.032 ± 0.653
0.0LysXaa: 0.0 ± 0.0
Leu
2.064LeuAla: 2.064 ± 0.239
1.032LeuCys: 1.032 ± 0.892
5.16LeuAsp: 5.16 ± 2.915
7.224LeuGlu: 7.224 ± 0.065
3.096LeuPhe: 3.096 ± 1.131
10.32LeuGly: 10.32 ± 0.349
2.064LeuHis: 2.064 ± 1.784
4.128LeuIle: 4.128 ± 2.023
2.064LeuLys: 2.064 ± 0.239
8.256LeuLeu: 8.256 ± 4.047
2.064LeuMet: 2.064 ± 1.306
4.128LeuAsn: 4.128 ± 1.067
2.064LeuPro: 2.064 ± 1.784
2.064LeuGln: 2.064 ± 0.239
6.192LeuArg: 6.192 ± 2.263
4.128LeuSer: 4.128 ± 0.478
2.064LeuThr: 2.064 ± 0.239
7.224LeuVal: 7.224 ± 1.61
1.032LeuTrp: 1.032 ± 0.892
4.128LeuTyr: 4.128 ± 0.478
0.0LeuXaa: 0.0 ± 0.0
Met
2.064MetAla: 2.064 ± 0.239
0.0MetCys: 0.0 ± 0.0
3.096MetAsp: 3.096 ± 0.414
2.064MetGlu: 2.064 ± 1.306
4.128MetPhe: 4.128 ± 0.478
1.032MetGly: 1.032 ± 0.892
1.032MetHis: 1.032 ± 0.653
0.0MetIle: 0.0 ± 0.0
3.096MetLys: 3.096 ± 0.414
2.064MetLeu: 2.064 ± 1.784
1.032MetMet: 1.032 ± 0.653
2.064MetAsn: 2.064 ± 0.239
0.0MetPro: 0.0 ± 0.0
1.032MetGln: 1.032 ± 0.653
3.096MetArg: 3.096 ± 2.676
2.064MetSer: 2.064 ± 0.239
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.032MetTrp: 1.032 ± 0.892
1.032MetTyr: 1.032 ± 0.653
0.0MetXaa: 0.0 ± 0.0
Asn
4.128AsnAla: 4.128 ± 2.612
0.0AsnCys: 0.0 ± 0.0
2.064AsnAsp: 2.064 ± 0.239
2.064AsnGlu: 2.064 ± 0.239
3.096AsnPhe: 3.096 ± 1.959
1.032AsnGly: 1.032 ± 0.892
1.032AsnHis: 1.032 ± 0.892
2.064AsnIle: 2.064 ± 0.239
1.032AsnLys: 1.032 ± 0.653
1.032AsnLeu: 1.032 ± 0.892
1.032AsnMet: 1.032 ± 0.892
1.032AsnAsn: 1.032 ± 0.892
3.096AsnPro: 3.096 ± 2.676
1.032AsnGln: 1.032 ± 0.892
2.064AsnArg: 2.064 ± 0.239
5.16AsnSer: 5.16 ± 0.175
1.032AsnThr: 1.032 ± 0.892
2.064AsnVal: 2.064 ± 1.306
1.032AsnTrp: 1.032 ± 0.892
1.032AsnTyr: 1.032 ± 0.653
0.0AsnXaa: 0.0 ± 0.0
Pro
1.032ProAla: 1.032 ± 0.892
0.0ProCys: 0.0 ± 0.0
3.096ProAsp: 3.096 ± 0.414
1.032ProGlu: 1.032 ± 0.892
2.064ProPhe: 2.064 ± 1.306
3.096ProGly: 3.096 ± 0.414
0.0ProHis: 0.0 ± 0.0
1.032ProIle: 1.032 ± 0.892
3.096ProLys: 3.096 ± 1.131
5.16ProLeu: 5.16 ± 2.915
0.0ProMet: 0.0 ± 0.0
4.128ProAsn: 4.128 ± 0.478
2.064ProPro: 2.064 ± 1.306
2.064ProGln: 2.064 ± 1.306
2.064ProArg: 2.064 ± 1.784
8.256ProSer: 8.256 ± 2.133
3.096ProThr: 3.096 ± 0.414
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
2.064ProTyr: 2.064 ± 0.239
0.0ProXaa: 0.0 ± 0.0
Gln
2.064GlnAla: 2.064 ± 1.306
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.096GlnGlu: 3.096 ± 2.676
2.064GlnPhe: 2.064 ± 1.784
1.032GlnGly: 1.032 ± 0.653
1.032GlnHis: 1.032 ± 0.653
5.16GlnIle: 5.16 ± 2.915
3.096GlnLys: 3.096 ± 1.131
1.032GlnLeu: 1.032 ± 0.892
1.032GlnMet: 1.032 ± 0.892
1.032GlnAsn: 1.032 ± 0.892
1.032GlnPro: 1.032 ± 0.653
1.032GlnGln: 1.032 ± 0.892
0.0GlnArg: 0.0 ± 0.0
1.032GlnSer: 1.032 ± 0.653
0.0GlnThr: 0.0 ± 0.0
2.064GlnVal: 2.064 ± 1.306
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.064ArgAla: 2.064 ± 1.784
0.0ArgCys: 0.0 ± 0.0
3.096ArgAsp: 3.096 ± 0.414
3.096ArgGlu: 3.096 ± 0.414
2.064ArgPhe: 2.064 ± 0.239
2.064ArgGly: 2.064 ± 0.239
0.0ArgHis: 0.0 ± 0.0
7.224ArgIle: 7.224 ± 1.48
5.16ArgLys: 5.16 ± 1.72
4.128ArgLeu: 4.128 ± 0.478
0.0ArgMet: 0.0 ± 0.0
1.032ArgAsn: 1.032 ± 0.653
1.032ArgPro: 1.032 ± 0.653
0.0ArgGln: 0.0 ± 0.0
3.096ArgArg: 3.096 ± 1.959
6.192ArgSer: 6.192 ± 0.828
3.096ArgThr: 3.096 ± 1.131
2.064ArgVal: 2.064 ± 1.784
1.032ArgTrp: 1.032 ± 0.892
6.192ArgTyr: 6.192 ± 2.263
0.0ArgXaa: 0.0 ± 0.0
Ser
4.128SerAla: 4.128 ± 2.612
1.032SerCys: 1.032 ± 0.653
6.192SerAsp: 6.192 ± 2.263
2.064SerGlu: 2.064 ± 0.239
5.16SerPhe: 5.16 ± 0.175
10.32SerGly: 10.32 ± 3.439
1.032SerHis: 1.032 ± 0.892
3.096SerIle: 3.096 ± 1.131
8.256SerLys: 8.256 ± 3.678
9.288SerLeu: 9.288 ± 0.304
0.0SerMet: 0.0 ± 0.476
1.032SerAsn: 1.032 ± 0.653
4.128SerPro: 4.128 ± 2.023
0.0SerGln: 0.0 ± 0.0
4.128SerArg: 4.128 ± 2.612
4.128SerSer: 4.128 ± 1.067
4.128SerThr: 4.128 ± 2.612
4.128SerVal: 4.128 ± 0.478
2.064SerTrp: 2.064 ± 0.239
1.032SerTyr: 1.032 ± 0.653
0.0SerXaa: 0.0 ± 0.0
Thr
2.064ThrAla: 2.064 ± 1.306
0.0ThrCys: 0.0 ± 0.0
2.064ThrAsp: 2.064 ± 1.306
1.032ThrGlu: 1.032 ± 0.653
3.096ThrPhe: 3.096 ± 1.959
0.0ThrGly: 0.0 ± 0.0
3.096ThrHis: 3.096 ± 0.414
6.192ThrIle: 6.192 ± 0.717
5.16ThrLys: 5.16 ± 0.175
3.096ThrLeu: 3.096 ± 1.131
0.0ThrMet: 0.0 ± 0.0
2.064ThrAsn: 2.064 ± 0.239
1.032ThrPro: 1.032 ± 0.653
1.032ThrGln: 1.032 ± 0.653
1.032ThrArg: 1.032 ± 0.892
5.16ThrSer: 5.16 ± 1.72
1.032ThrThr: 1.032 ± 0.653
3.096ThrVal: 3.096 ± 0.414
1.032ThrTrp: 1.032 ± 0.892
2.064ThrTyr: 2.064 ± 0.239
0.0ThrXaa: 0.0 ± 0.0
Val
2.064ValAla: 2.064 ± 1.306
1.032ValCys: 1.032 ± 0.653
3.096ValAsp: 3.096 ± 1.131
2.064ValGlu: 2.064 ± 1.306
2.064ValPhe: 2.064 ± 1.784
5.16ValGly: 5.16 ± 1.72
0.0ValHis: 0.0 ± 0.0
5.16ValIle: 5.16 ± 0.175
7.224ValLys: 7.224 ± 1.48
5.16ValLeu: 5.16 ± 1.72
2.064ValMet: 2.064 ± 0.239
3.096ValAsn: 3.096 ± 2.676
5.16ValPro: 5.16 ± 1.72
3.096ValGln: 3.096 ± 1.131
4.128ValArg: 4.128 ± 1.067
5.16ValSer: 5.16 ± 1.72
1.032ValThr: 1.032 ± 0.653
8.256ValVal: 8.256 ± 2.133
2.064ValTrp: 2.064 ± 0.239
1.032ValTyr: 1.032 ± 0.653
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
3.096TrpAsp: 3.096 ± 1.131
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.032TrpIle: 1.032 ± 0.892
1.032TrpLys: 1.032 ± 0.892
1.032TrpLeu: 1.032 ± 0.892
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.032TrpPro: 1.032 ± 0.892
0.0TrpGln: 0.0 ± 0.0
4.128TrpArg: 4.128 ± 2.023
2.064TrpSer: 2.064 ± 0.239
5.16TrpThr: 5.16 ± 1.37
0.0TrpVal: 0.0 ± 0.0
1.032TrpTrp: 1.032 ± 0.892
2.064TrpTyr: 2.064 ± 0.239
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.032TyrAla: 1.032 ± 0.892
0.0TyrCys: 0.0 ± 0.0
2.064TyrAsp: 2.064 ± 1.306
2.064TyrGlu: 2.064 ± 1.306
2.064TyrPhe: 2.064 ± 1.306
2.064TyrGly: 2.064 ± 1.306
1.032TyrHis: 1.032 ± 0.892
5.16TyrIle: 5.16 ± 1.72
4.128TyrLys: 4.128 ± 0.478
3.096TyrLeu: 3.096 ± 0.414
2.064TyrMet: 2.064 ± 1.784
2.064TyrAsn: 2.064 ± 0.239
1.032TyrPro: 1.032 ± 0.892
1.032TyrGln: 1.032 ± 0.653
0.0TyrArg: 0.0 ± 0.0
2.064TyrSer: 2.064 ± 0.239
3.096TyrThr: 3.096 ± 0.414
3.096TyrVal: 3.096 ± 1.959
1.032TyrTrp: 1.032 ± 0.892
1.032TyrTyr: 1.032 ± 0.653
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (970 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski