Amino acid dipepetide frequency for Wild carrot mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.249AlaAla: 11.249 ± 2.049
0.562AlaCys: 0.562 ± 0.604
1.687AlaAsp: 1.687 ± 0.594
7.874AlaGlu: 7.874 ± 3.171
4.499AlaPhe: 4.499 ± 1.23
5.624AlaGly: 5.624 ± 1.241
1.687AlaHis: 1.687 ± 1.106
2.812AlaIle: 2.812 ± 1.457
5.062AlaLys: 5.062 ± 2.377
5.624AlaLeu: 5.624 ± 0.717
4.499AlaMet: 4.499 ± 1.651
4.499AlaAsn: 4.499 ± 1.423
7.312AlaPro: 7.312 ± 1.528
4.499AlaGln: 4.499 ± 0.714
4.499AlaArg: 4.499 ± 2.716
6.187AlaSer: 6.187 ± 1.707
3.937AlaThr: 3.937 ± 1.518
8.436AlaVal: 8.436 ± 1.925
0.0AlaTrp: 0.0 ± 0.0
1.125AlaTyr: 1.125 ± 0.551
0.0AlaXaa: 0.0 ± 0.0
Cys
1.125CysAla: 1.125 ± 0.53
0.0CysCys: 0.0 ± 0.0
1.125CysAsp: 1.125 ± 0.53
0.0CysGlu: 0.0 ± 0.0
1.687CysPhe: 1.687 ± 0.723
3.375CysGly: 3.375 ± 0.883
0.0CysHis: 0.0 ± 0.0
1.687CysIle: 1.687 ± 0.714
0.562CysLys: 0.562 ± 0.604
0.562CysLeu: 0.562 ± 0.341
0.562CysMet: 0.562 ± 0.548
1.125CysAsn: 1.125 ± 0.53
1.687CysPro: 1.687 ± 1.813
1.125CysGln: 1.125 ± 0.551
2.25CysArg: 2.25 ± 1.102
1.687CysSer: 1.687 ± 0.594
0.562CysThr: 0.562 ± 0.341
1.125CysVal: 1.125 ± 0.681
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
10.124AspAla: 10.124 ± 3.562
1.687AspCys: 1.687 ± 0.594
2.25AspAsp: 2.25 ± 0.81
1.687AspGlu: 1.687 ± 0.649
1.687AspPhe: 1.687 ± 0.594
3.937AspGly: 3.937 ± 0.98
0.0AspHis: 0.0 ± 0.0
0.562AspIle: 0.562 ± 0.341
0.562AspLys: 0.562 ± 0.341
2.25AspLeu: 2.25 ± 0.615
0.562AspMet: 0.562 ± 0.341
1.125AspAsn: 1.125 ± 0.681
5.062AspPro: 5.062 ± 1.285
0.562AspGln: 0.562 ± 0.341
1.125AspArg: 1.125 ± 0.681
2.812AspSer: 2.812 ± 1.064
5.062AspThr: 5.062 ± 0.782
2.812AspVal: 2.812 ± 0.683
1.687AspTrp: 1.687 ± 0.594
0.562AspTyr: 0.562 ± 0.341
0.0AspXaa: 0.0 ± 0.0
Glu
6.187GluAla: 6.187 ± 1.27
1.125GluCys: 1.125 ± 1.209
3.937GluAsp: 3.937 ± 0.993
5.062GluGlu: 5.062 ± 1.606
1.125GluPhe: 1.125 ± 0.681
6.187GluGly: 6.187 ± 1.971
2.812GluHis: 2.812 ± 1.091
2.25GluIle: 2.25 ± 0.81
1.125GluLys: 1.125 ± 0.614
6.749GluLeu: 6.749 ± 2.264
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
4.499GluPro: 4.499 ± 1.521
3.375GluGln: 3.375 ± 0.883
6.749GluArg: 6.749 ± 1.021
5.624GluSer: 5.624 ± 1.241
2.812GluThr: 2.812 ± 0.929
3.937GluVal: 3.937 ± 1.399
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.375PheAla: 3.375 ± 1.399
1.687PheCys: 1.687 ± 0.577
1.687PheAsp: 1.687 ± 1.022
0.562PheGlu: 0.562 ± 0.341
0.562PhePhe: 0.562 ± 0.341
1.687PheGly: 1.687 ± 0.594
0.0PheHis: 0.0 ± 0.0
1.687PheIle: 1.687 ± 0.714
0.562PheLys: 0.562 ± 0.341
2.25PheLeu: 2.25 ± 0.476
0.0PheMet: 0.0 ± 0.0
2.812PheAsn: 2.812 ± 1.229
0.562PhePro: 0.562 ± 0.341
0.562PheGln: 0.562 ± 0.341
2.812PheArg: 2.812 ± 0.912
1.687PheSer: 1.687 ± 1.26
2.812PheThr: 2.812 ± 0.683
1.125PheVal: 1.125 ± 0.551
0.0PheTrp: 0.0 ± 0.0
2.812PheTyr: 2.812 ± 0.683
0.0PheXaa: 0.0 ± 0.0
Gly
6.749GlyAla: 6.749 ± 3.694
1.125GlyCys: 1.125 ± 0.551
5.062GlyAsp: 5.062 ± 1.781
10.686GlyGlu: 10.686 ± 2.928
1.687GlyPhe: 1.687 ± 0.689
8.436GlyGly: 8.436 ± 2.461
1.125GlyHis: 1.125 ± 0.53
3.937GlyIle: 3.937 ± 0.98
0.562GlyLys: 0.562 ± 0.341
4.499GlyLeu: 4.499 ± 1.292
2.812GlyMet: 2.812 ± 1.213
5.062GlyAsn: 5.062 ± 2.024
4.499GlyPro: 4.499 ± 1.259
1.125GlyGln: 1.125 ± 0.53
8.999GlyArg: 8.999 ± 2.299
4.499GlySer: 4.499 ± 1.149
5.062GlyThr: 5.062 ± 0.684
4.499GlyVal: 4.499 ± 1.292
0.0GlyTrp: 0.0 ± 0.0
0.562GlyTyr: 0.562 ± 0.604
0.0GlyXaa: 0.0 ± 0.0
His
0.562HisAla: 0.562 ± 0.604
1.125HisCys: 1.125 ± 0.53
1.687HisAsp: 1.687 ± 0.714
1.687HisGlu: 1.687 ± 0.594
0.0HisPhe: 0.0 ± 0.0
2.25HisGly: 2.25 ± 1.094
0.0HisHis: 0.0 ± 0.0
1.687HisIle: 1.687 ± 0.594
0.562HisLys: 0.562 ± 0.341
2.25HisLeu: 2.25 ± 0.936
0.0HisMet: 0.0 ± 0.0
1.125HisAsn: 1.125 ± 0.614
2.25HisPro: 2.25 ± 1.102
1.687HisGln: 1.687 ± 0.577
0.0HisArg: 0.0 ± 0.0
2.25HisSer: 2.25 ± 1.102
2.25HisThr: 2.25 ± 1.826
1.687HisVal: 1.687 ± 0.714
0.0HisTrp: 0.0 ± 0.0
0.562HisTyr: 0.562 ± 0.604
0.0HisXaa: 0.0 ± 0.0
Ile
1.125IleAla: 1.125 ± 0.551
0.0IleCys: 0.0 ± 0.0
1.687IleAsp: 1.687 ± 0.689
3.375IleGlu: 3.375 ± 0.972
0.562IlePhe: 0.562 ± 0.341
3.375IleGly: 3.375 ± 0.143
0.0IleHis: 0.0 ± 0.0
2.812IleIle: 2.812 ± 0.332
1.687IleLys: 1.687 ± 0.714
3.375IleLeu: 3.375 ± 1.591
0.0IleMet: 0.0 ± 0.0
2.25IleAsn: 2.25 ± 0.614
8.436IlePro: 8.436 ± 0.321
1.687IleGln: 1.687 ± 0.714
0.562IleArg: 0.562 ± 0.341
4.499IleSer: 4.499 ± 1.457
1.125IleThr: 1.125 ± 0.681
2.25IleVal: 2.25 ± 0.81
0.562IleTrp: 0.562 ± 0.69
2.25IleTyr: 2.25 ± 0.936
0.0IleXaa: 0.0 ± 0.0
Lys
2.812LysAla: 2.812 ± 1.091
0.562LysCys: 0.562 ± 0.341
3.375LysAsp: 3.375 ± 1.399
0.562LysGlu: 0.562 ± 0.69
1.125LysPhe: 1.125 ± 0.681
3.375LysGly: 3.375 ± 1.516
0.562LysHis: 0.562 ± 0.341
0.562LysIle: 0.562 ± 0.341
0.0LysLys: 0.0 ± 0.0
3.375LysLeu: 3.375 ± 0.993
0.0LysMet: 0.0 ± 0.0
0.562LysAsn: 0.562 ± 0.341
2.812LysPro: 2.812 ± 1.213
0.0LysGln: 0.0 ± 0.0
1.687LysArg: 1.687 ± 0.714
0.562LysSer: 0.562 ± 0.69
2.25LysThr: 2.25 ± 0.615
5.062LysVal: 5.062 ± 1.329
1.125LysTrp: 1.125 ± 0.681
2.812LysTyr: 2.812 ± 1.091
0.0LysXaa: 0.0 ± 0.0
Leu
6.187LeuAla: 6.187 ± 1.378
2.25LeuCys: 2.25 ± 0.936
3.375LeuAsp: 3.375 ± 0.971
3.937LeuGlu: 3.937 ± 1.154
1.687LeuPhe: 1.687 ± 0.649
6.187LeuGly: 6.187 ± 1.319
1.125LeuHis: 1.125 ± 0.836
2.812LeuIle: 2.812 ± 0.332
2.25LeuLys: 2.25 ± 0.935
5.062LeuLeu: 5.062 ± 0.729
3.937LeuMet: 3.937 ± 1.245
1.125LeuAsn: 1.125 ± 0.836
2.25LeuPro: 2.25 ± 1.227
2.25LeuGln: 2.25 ± 1.102
4.499LeuArg: 4.499 ± 1.439
8.999LeuSer: 8.999 ± 0.699
5.062LeuThr: 5.062 ± 2.298
7.312LeuVal: 7.312 ± 2.129
2.25LeuTrp: 2.25 ± 0.476
2.812LeuTyr: 2.812 ± 1.287
0.0LeuXaa: 0.0 ± 0.0
Met
1.125MetAla: 1.125 ± 0.53
0.0MetCys: 0.0 ± 0.0
2.812MetAsp: 2.812 ± 1.091
3.937MetGlu: 3.937 ± 0.993
0.562MetPhe: 0.562 ± 0.341
0.562MetGly: 0.562 ± 0.604
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.687MetLys: 1.687 ± 0.594
1.125MetLeu: 1.125 ± 0.614
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.125MetPro: 1.125 ± 0.53
0.562MetGln: 0.562 ± 0.341
0.562MetArg: 0.562 ± 0.341
2.25MetSer: 2.25 ± 0.476
2.812MetThr: 2.812 ± 0.332
2.25MetVal: 2.25 ± 1.362
0.562MetTrp: 0.562 ± 0.69
0.562MetTyr: 0.562 ± 0.341
0.0MetXaa: 0.0 ± 0.0
Asn
5.624AsnAla: 5.624 ± 1.241
0.562AsnCys: 0.562 ± 0.341
0.562AsnAsp: 0.562 ± 0.341
1.125AsnGlu: 1.125 ± 0.614
0.562AsnPhe: 0.562 ± 0.341
2.25AsnGly: 2.25 ± 0.81
0.0AsnHis: 0.0 ± 0.0
1.125AsnIle: 1.125 ± 0.614
2.25AsnLys: 2.25 ± 1.362
1.125AsnLeu: 1.125 ± 0.614
0.562AsnMet: 0.562 ± 0.341
2.25AsnAsn: 2.25 ± 1.094
1.687AsnPro: 1.687 ± 1.106
0.562AsnGln: 0.562 ± 0.604
1.687AsnArg: 1.687 ± 1.813
2.812AsnSer: 2.812 ± 1.639
1.125AsnThr: 1.125 ± 0.836
2.25AsnVal: 2.25 ± 0.476
0.0AsnTrp: 0.0 ± 0.0
1.125AsnTyr: 1.125 ± 0.836
0.0AsnXaa: 0.0 ± 0.0
Pro
9.561ProAla: 9.561 ± 2.109
1.125ProCys: 1.125 ± 0.551
2.812ProAsp: 2.812 ± 0.683
3.937ProGlu: 3.937 ± 1.329
1.125ProPhe: 1.125 ± 0.681
5.624ProGly: 5.624 ± 1.427
3.375ProHis: 3.375 ± 1.518
3.375ProIle: 3.375 ± 0.143
0.0ProLys: 0.0 ± 0.0
6.749ProLeu: 6.749 ± 1.229
1.125ProMet: 1.125 ± 0.55
1.125ProAsn: 1.125 ± 0.836
2.25ProPro: 2.25 ± 1.671
1.687ProGln: 1.687 ± 0.577
7.312ProArg: 7.312 ± 1.73
1.687ProSer: 1.687 ± 1.106
10.124ProThr: 10.124 ± 2.424
9.561ProVal: 9.561 ± 1.131
0.562ProTrp: 0.562 ± 0.341
3.937ProTyr: 3.937 ± 1.399
0.0ProXaa: 0.0 ± 0.0
Gln
1.687GlnAla: 1.687 ± 0.689
1.687GlnCys: 1.687 ± 0.577
0.0GlnAsp: 0.0 ± 0.0
1.125GlnGlu: 1.125 ± 0.53
1.687GlnPhe: 1.687 ± 0.594
1.125GlnGly: 1.125 ± 1.209
1.125GlnHis: 1.125 ± 0.551
1.687GlnIle: 1.687 ± 1.022
1.125GlnLys: 1.125 ± 1.379
6.187GlnLeu: 6.187 ± 1.541
0.0GlnMet: 0.0 ± 0.0
0.562GlnAsn: 0.562 ± 0.604
3.937GlnPro: 3.937 ± 0.553
1.125GlnGln: 1.125 ± 0.681
1.687GlnArg: 1.687 ± 2.069
2.25GlnSer: 2.25 ± 1.221
1.687GlnThr: 1.687 ± 0.594
3.375GlnVal: 3.375 ± 0.883
0.0GlnTrp: 0.0 ± 0.0
1.687GlnTyr: 1.687 ± 1.285
0.0GlnXaa: 0.0 ± 0.0
Arg
5.624ArgAla: 5.624 ± 1.427
0.562ArgCys: 0.562 ± 0.69
2.812ArgAsp: 2.812 ± 0.594
6.187ArgGlu: 6.187 ± 1.971
3.375ArgPhe: 3.375 ± 0.843
6.187ArgGly: 6.187 ± 3.147
2.25ArgHis: 2.25 ± 1.094
1.125ArgIle: 1.125 ± 0.551
1.125ArgLys: 1.125 ± 0.53
4.499ArgLeu: 4.499 ± 1.578
3.375ArgMet: 3.375 ± 1.187
0.0ArgAsn: 0.0 ± 0.0
4.499ArgPro: 4.499 ± 1.171
2.812ArgGln: 2.812 ± 0.988
3.375ArgArg: 3.375 ± 1.742
3.375ArgSer: 3.375 ± 1.154
3.937ArgThr: 3.937 ± 3.031
5.062ArgVal: 5.062 ± 1.285
2.25ArgTrp: 2.25 ± 0.615
3.937ArgTyr: 3.937 ± 0.8
0.0ArgXaa: 0.0 ± 0.0
Ser
2.25SerAla: 2.25 ± 1.309
1.687SerCys: 1.687 ± 0.577
3.375SerAsp: 3.375 ± 0.853
5.624SerGlu: 5.624 ± 1.859
1.687SerPhe: 1.687 ± 1.022
3.375SerGly: 3.375 ± 2.223
1.687SerHis: 1.687 ± 0.577
3.375SerIle: 3.375 ± 0.143
2.812SerLys: 2.812 ± 0.683
6.749SerLeu: 6.749 ± 1.229
1.687SerMet: 1.687 ± 0.649
1.687SerAsn: 1.687 ± 1.022
5.624SerPro: 5.624 ± 0.663
1.687SerGln: 1.687 ± 2.069
7.312SerArg: 7.312 ± 1.751
6.749SerSer: 6.749 ± 1.695
3.375SerThr: 3.375 ± 0.972
6.749SerVal: 6.749 ± 1.417
0.562SerTrp: 0.562 ± 0.341
3.937SerTyr: 3.937 ± 0.553
0.0SerXaa: 0.0 ± 0.0
Thr
7.874ThrAla: 7.874 ± 1.313
1.687ThrCys: 1.687 ± 0.594
1.687ThrAsp: 1.687 ± 0.594
1.125ThrGlu: 1.125 ± 0.681
1.687ThrPhe: 1.687 ± 1.106
7.874ThrGly: 7.874 ± 1.312
3.375ThrHis: 3.375 ± 0.757
3.375ThrIle: 3.375 ± 1.445
3.375ThrLys: 3.375 ± 0.143
3.375ThrLeu: 3.375 ± 0.972
1.687ThrMet: 1.687 ± 0.772
2.25ThrAsn: 2.25 ± 0.657
9.561ThrPro: 9.561 ± 1.952
3.937ThrGln: 3.937 ± 2.483
2.812ThrArg: 2.812 ± 1.073
2.25ThrSer: 2.25 ± 0.476
3.375ThrThr: 3.375 ± 0.757
3.375ThrVal: 3.375 ± 1.866
0.562ThrTrp: 0.562 ± 0.604
0.562ThrTyr: 0.562 ± 0.69
0.0ThrXaa: 0.0 ± 0.0
Val
6.749ValAla: 6.749 ± 0.813
1.687ValCys: 1.687 ± 0.714
2.812ValAsp: 2.812 ± 1.064
3.375ValGlu: 3.375 ± 0.143
2.25ValPhe: 2.25 ± 0.614
6.749ValGly: 6.749 ± 0.813
3.937ValHis: 3.937 ± 1.279
3.375ValIle: 3.375 ± 1.542
3.937ValLys: 3.937 ± 1.719
5.062ValLeu: 5.062 ± 1.021
0.562ValMet: 0.562 ± 0.69
0.562ValAsn: 0.562 ± 0.341
5.624ValPro: 5.624 ± 0.998
2.25ValGln: 2.25 ± 1.061
5.624ValArg: 5.624 ± 1.366
4.499ValSer: 4.499 ± 1.051
8.436ValThr: 8.436 ± 1.858
5.062ValVal: 5.062 ± 1.606
0.0ValTrp: 0.0 ± 0.0
6.187ValTyr: 6.187 ± 1.417
0.0ValXaa: 0.0 ± 0.0
Trp
1.687TrpAla: 1.687 ± 0.577
0.0TrpCys: 0.0 ± 0.0
0.562TrpAsp: 0.562 ± 0.341
0.562TrpGlu: 0.562 ± 0.341
1.687TrpPhe: 1.687 ± 0.594
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.562TrpLeu: 0.562 ± 0.341
0.0TrpMet: 0.0 ± 0.0
0.562TrpAsn: 0.562 ± 0.341
0.562TrpPro: 0.562 ± 0.604
0.562TrpGln: 0.562 ± 0.69
1.687TrpArg: 1.687 ± 0.649
0.0TrpSer: 0.0 ± 0.0
0.562TrpThr: 0.562 ± 0.341
0.562TrpVal: 0.562 ± 0.69
0.562TrpTrp: 0.562 ± 0.341
1.125TrpTyr: 1.125 ± 0.53
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.125TyrCys: 1.125 ± 0.53
2.812TyrAsp: 2.812 ± 1.2
1.125TyrGlu: 1.125 ± 0.551
0.0TyrPhe: 0.0 ± 0.0
2.812TyrGly: 2.812 ± 0.594
0.562TyrHis: 0.562 ± 0.341
3.375TyrIle: 3.375 ± 1.187
3.937TyrLys: 3.937 ± 1.833
3.937TyrLeu: 3.937 ± 0.8
0.562TyrMet: 0.562 ± 0.604
0.562TyrAsn: 0.562 ± 0.341
2.812TyrPro: 2.812 ± 1.874
1.687TyrGln: 1.687 ± 0.689
1.125TyrArg: 1.125 ± 0.551
7.312TyrSer: 7.312 ± 1.788
0.0TyrThr: 0.0 ± 0.0
2.25TyrVal: 2.25 ± 0.615
0.562TyrTrp: 0.562 ± 0.604
1.125TyrTyr: 1.125 ± 0.53
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1779 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski