Amino acid dipepetide frequency for Riverside virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.462AlaAla: 2.462 ± 0.651
0.547AlaCys: 0.547 ± 0.327
3.283AlaAsp: 3.283 ± 0.584
1.642AlaGlu: 1.642 ± 0.237
2.736AlaPhe: 2.736 ± 0.787
3.557AlaGly: 3.557 ± 1.36
1.094AlaHis: 1.094 ± 0.643
4.104AlaIle: 4.104 ± 1.158
1.642AlaLys: 1.642 ± 0.58
5.746AlaLeu: 5.746 ± 0.744
0.547AlaMet: 0.547 ± 0.321
1.642AlaAsn: 1.642 ± 0.986
1.368AlaPro: 1.368 ± 1.015
1.915AlaGln: 1.915 ± 0.508
3.01AlaArg: 3.01 ± 0.442
3.557AlaSer: 3.557 ± 0.363
3.283AlaThr: 3.283 ± 1.176
3.283AlaVal: 3.283 ± 1.661
0.547AlaTrp: 0.547 ± 0.327
1.915AlaTyr: 1.915 ± 0.587
0.0AlaXaa: 0.0 ± 0.0
Cys
0.821CysAla: 0.821 ± 0.712
0.0CysCys: 0.0 ± 0.0
0.547CysAsp: 0.547 ± 0.321
0.821CysGlu: 0.821 ± 0.308
0.547CysPhe: 0.547 ± 0.321
0.274CysGly: 0.274 ± 0.372
0.547CysHis: 0.547 ± 0.329
0.274CysIle: 0.274 ± 0.399
1.094CysLys: 1.094 ± 0.481
1.642CysLeu: 1.642 ± 0.524
0.0CysMet: 0.0 ± 0.0
0.274CysAsn: 0.274 ± 0.372
1.094CysPro: 1.094 ± 1.026
0.274CysGln: 0.274 ± 0.161
1.368CysArg: 1.368 ± 0.795
1.642CysSer: 1.642 ± 0.765
1.642CysThr: 1.642 ± 0.616
0.547CysVal: 0.547 ± 0.301
0.547CysTrp: 0.547 ± 0.321
0.274CysTyr: 0.274 ± 0.161
0.0CysXaa: 0.0 ± 0.0
Asp
3.01AspAla: 3.01 ± 0.705
1.368AspCys: 1.368 ± 0.519
3.01AspAsp: 3.01 ± 0.364
3.01AspGlu: 3.01 ± 1.341
1.915AspPhe: 1.915 ± 0.773
3.557AspGly: 3.557 ± 0.35
1.642AspHis: 1.642 ± 0.877
4.378AspIle: 4.378 ± 1.108
4.104AspLys: 4.104 ± 1.078
6.293AspLeu: 6.293 ± 1.814
1.368AspMet: 1.368 ± 0.309
1.094AspAsn: 1.094 ± 0.388
4.378AspPro: 4.378 ± 1.584
3.01AspGln: 3.01 ± 1.175
1.642AspArg: 1.642 ± 0.237
3.557AspSer: 3.557 ± 0.562
3.557AspThr: 3.557 ± 1.375
1.368AspVal: 1.368 ± 0.314
1.642AspTrp: 1.642 ± 0.557
3.83AspTyr: 3.83 ± 1.223
0.0AspXaa: 0.0 ± 0.0
Glu
1.915GluAla: 1.915 ± 0.773
1.094GluCys: 1.094 ± 0.726
3.01GluAsp: 3.01 ± 0.888
1.915GluGlu: 1.915 ± 0.481
3.83GluPhe: 3.83 ± 0.611
4.104GluGly: 4.104 ± 1.058
1.368GluHis: 1.368 ± 0.953
2.736GluIle: 2.736 ± 0.953
3.283GluLys: 3.283 ± 0.824
5.198GluLeu: 5.198 ± 0.465
1.915GluMet: 1.915 ± 0.649
1.368GluAsn: 1.368 ± 0.688
2.736GluPro: 2.736 ± 0.829
1.094GluGln: 1.094 ± 1.271
3.01GluArg: 3.01 ± 0.928
4.651GluSer: 4.651 ± 2.077
3.01GluThr: 3.01 ± 0.873
4.104GluVal: 4.104 ± 0.826
0.547GluTrp: 0.547 ± 0.798
3.01GluTyr: 3.01 ± 1.113
0.0GluXaa: 0.0 ± 0.0
Phe
3.557PheAla: 3.557 ± 0.929
0.547PheCys: 0.547 ± 0.301
1.094PheAsp: 1.094 ± 0.766
1.642PheGlu: 1.642 ± 0.237
2.189PhePhe: 2.189 ± 0.581
2.189PheGly: 2.189 ± 0.559
2.462PheHis: 2.462 ± 0.57
0.821PheIle: 0.821 ± 0.308
3.83PheLys: 3.83 ± 0.778
4.925PheLeu: 4.925 ± 1.014
0.821PheMet: 0.821 ± 0.326
0.821PheAsn: 0.821 ± 0.326
2.462PhePro: 2.462 ± 0.57
1.642PheGln: 1.642 ± 0.701
2.736PheArg: 2.736 ± 0.931
1.368PheSer: 1.368 ± 0.507
2.462PheThr: 2.462 ± 1.106
3.83PheVal: 3.83 ± 0.51
0.821PheTrp: 0.821 ± 0.308
1.915PheTyr: 1.915 ± 1.256
0.0PheXaa: 0.0 ± 0.0
Gly
2.189GlyAla: 2.189 ± 0.861
0.821GlyCys: 0.821 ± 0.482
4.651GlyAsp: 4.651 ± 0.968
3.283GlyGlu: 3.283 ± 1.007
2.462GlyPhe: 2.462 ± 0.762
4.378GlyGly: 4.378 ± 1.558
0.274GlyHis: 0.274 ± 0.161
4.925GlyIle: 4.925 ± 0.988
3.83GlyLys: 3.83 ± 1.48
9.576GlyLeu: 9.576 ± 0.821
1.094GlyMet: 1.094 ± 0.396
3.01GlyAsn: 3.01 ± 1.1
2.462GlyPro: 2.462 ± 1.084
1.094GlyGln: 1.094 ± 0.643
2.462GlyArg: 2.462 ± 1.311
5.198GlySer: 5.198 ± 1.161
3.83GlyThr: 3.83 ± 1.086
2.736GlyVal: 2.736 ± 0.515
1.094GlyTrp: 1.094 ± 0.643
1.368GlyTyr: 1.368 ± 0.519
0.0GlyXaa: 0.0 ± 0.0
His
0.821HisAla: 0.821 ± 0.548
0.274HisCys: 0.274 ± 0.372
0.274HisAsp: 0.274 ± 0.161
1.915HisGlu: 1.915 ± 0.506
1.368HisPhe: 1.368 ± 0.309
0.547HisGly: 0.547 ± 0.321
0.0HisHis: 0.0 ± 0.0
0.821HisIle: 0.821 ± 0.482
1.642HisLys: 1.642 ± 0.964
3.283HisLeu: 3.283 ± 1.601
0.274HisMet: 0.274 ± 0.161
0.821HisAsn: 0.821 ± 0.482
2.462HisPro: 2.462 ± 0.954
1.642HisGln: 1.642 ± 0.455
1.642HisArg: 1.642 ± 0.353
2.189HisSer: 2.189 ± 0.775
2.189HisThr: 2.189 ± 0.523
1.368HisVal: 1.368 ± 0.314
0.821HisTrp: 0.821 ± 0.308
1.368HisTyr: 1.368 ± 0.948
0.0HisXaa: 0.0 ± 0.0
Ile
3.83IleAla: 3.83 ± 0.908
0.821IleCys: 0.821 ± 0.326
3.01IleAsp: 3.01 ± 0.793
3.557IleGlu: 3.557 ± 1.079
3.01IlePhe: 3.01 ± 0.847
6.019IleGly: 6.019 ± 1.861
0.547IleHis: 0.547 ± 0.321
5.746IleIle: 5.746 ± 2.394
6.293IleLys: 6.293 ± 1.257
5.198IleLeu: 5.198 ± 0.918
0.821IleMet: 0.821 ± 0.712
4.378IleAsn: 4.378 ± 0.951
3.283IlePro: 3.283 ± 0.609
2.462IleGln: 2.462 ± 0.923
3.557IleArg: 3.557 ± 0.32
5.198IleSer: 5.198 ± 1.304
3.01IleThr: 3.01 ± 1.059
4.104IleVal: 4.104 ± 1.737
1.368IleTrp: 1.368 ± 0.51
2.189IleTyr: 2.189 ± 0.775
0.0IleXaa: 0.0 ± 0.0
Lys
3.557LysAla: 3.557 ± 1.245
0.821LysCys: 0.821 ± 0.326
4.378LysAsp: 4.378 ± 1.181
4.925LysGlu: 4.925 ± 1.478
1.915LysPhe: 1.915 ± 0.554
3.01LysGly: 3.01 ± 0.304
1.094LysHis: 1.094 ± 0.643
4.104LysIle: 4.104 ± 0.894
4.925LysLys: 4.925 ± 1.864
5.472LysLeu: 5.472 ± 1.365
1.368LysMet: 1.368 ± 0.52
3.557LysAsn: 3.557 ± 0.773
3.283LysPro: 3.283 ± 1.305
1.915LysGln: 1.915 ± 1.287
3.01LysArg: 3.01 ± 0.59
6.566LysSer: 6.566 ± 1.168
1.915LysThr: 1.915 ± 0.791
2.189LysVal: 2.189 ± 0.559
1.368LysTrp: 1.368 ± 0.803
2.189LysTyr: 2.189 ± 0.942
0.0LysXaa: 0.0 ± 0.0
Leu
4.651LeuAla: 4.651 ± 0.974
0.821LeuCys: 0.821 ± 0.658
5.198LeuAsp: 5.198 ± 0.809
4.378LeuGlu: 4.378 ± 2.085
3.283LeuPhe: 3.283 ± 0.928
7.387LeuGly: 7.387 ± 1.74
2.462LeuHis: 2.462 ± 1.031
7.934LeuIle: 7.934 ± 1.428
5.746LeuLys: 5.746 ± 2.636
8.482LeuLeu: 8.482 ± 1.47
4.378LeuMet: 4.378 ± 1.429
4.925LeuAsn: 4.925 ± 1.162
3.283LeuPro: 3.283 ± 0.988
2.736LeuGln: 2.736 ± 0.881
5.472LeuArg: 5.472 ± 1.532
9.302LeuSer: 9.302 ± 1.138
7.387LeuThr: 7.387 ± 1.121
5.746LeuVal: 5.746 ± 0.345
1.642LeuTrp: 1.642 ± 0.557
3.557LeuTyr: 3.557 ± 0.581
0.0LeuXaa: 0.0 ± 0.0
Met
2.189MetAla: 2.189 ± 0.559
0.274MetCys: 0.274 ± 0.442
1.915MetAsp: 1.915 ± 1.358
1.368MetGlu: 1.368 ± 0.314
1.094MetPhe: 1.094 ± 0.343
0.821MetGly: 0.821 ± 0.438
0.547MetHis: 0.547 ± 0.327
2.189MetIle: 2.189 ± 0.793
1.094MetLys: 1.094 ± 0.388
2.189MetLeu: 2.189 ± 0.527
1.094MetMet: 1.094 ± 0.784
1.642MetAsn: 1.642 ± 0.616
0.821MetPro: 0.821 ± 0.449
0.547MetGln: 0.547 ± 0.321
1.094MetArg: 1.094 ± 0.481
2.189MetSer: 2.189 ± 1.231
0.821MetThr: 0.821 ± 0.482
0.821MetVal: 0.821 ± 0.308
0.547MetTrp: 0.547 ± 0.321
1.642MetTyr: 1.642 ± 0.643
0.0MetXaa: 0.0 ± 0.0
Asn
2.736AsnAla: 2.736 ± 0.762
0.547AsnCys: 0.547 ± 0.321
3.01AsnAsp: 3.01 ± 0.527
2.736AsnGlu: 2.736 ± 0.752
1.915AsnPhe: 1.915 ± 0.791
2.189AsnGly: 2.189 ± 0.758
1.368AsnHis: 1.368 ± 0.507
2.189AsnIle: 2.189 ± 0.523
3.557AsnLys: 3.557 ± 0.78
4.651AsnLeu: 4.651 ± 1.309
1.094AsnMet: 1.094 ± 0.814
2.736AsnAsn: 2.736 ± 0.874
2.736AsnPro: 2.736 ± 0.481
1.368AsnGln: 1.368 ± 0.554
2.736AsnArg: 2.736 ± 0.774
3.83AsnSer: 3.83 ± 1.531
3.557AsnThr: 3.557 ± 1.027
3.283AsnVal: 3.283 ± 0.916
0.547AsnTrp: 0.547 ± 0.321
1.094AsnTyr: 1.094 ± 0.603
0.0AsnXaa: 0.0 ± 0.0
Pro
3.01ProAla: 3.01 ± 0.938
1.094ProCys: 1.094 ± 0.388
3.01ProAsp: 3.01 ± 0.442
3.83ProGlu: 3.83 ± 2.077
1.368ProPhe: 1.368 ± 0.356
3.283ProGly: 3.283 ± 1.072
1.094ProHis: 1.094 ± 0.643
3.557ProIle: 3.557 ± 1.662
1.368ProLys: 1.368 ± 0.554
4.651ProLeu: 4.651 ± 0.389
1.915ProMet: 1.915 ± 0.501
2.736ProAsn: 2.736 ± 1.366
2.462ProPro: 2.462 ± 1.42
2.189ProGln: 2.189 ± 0.581
2.736ProArg: 2.736 ± 0.515
5.472ProSer: 5.472 ± 0.646
1.915ProThr: 1.915 ± 1.276
3.01ProVal: 3.01 ± 1.207
0.274ProTrp: 0.274 ± 0.161
2.736ProTyr: 2.736 ± 1.414
0.0ProXaa: 0.0 ± 0.0
Gln
1.915GlnAla: 1.915 ± 0.508
0.547GlnCys: 0.547 ± 0.327
2.189GlnAsp: 2.189 ± 0.394
3.01GlnGlu: 3.01 ± 0.866
1.094GlnPhe: 1.094 ± 0.784
1.915GlnGly: 1.915 ± 0.835
0.821GlnHis: 0.821 ± 0.482
0.821GlnIle: 0.821 ± 0.482
1.915GlnLys: 1.915 ± 0.835
2.736GlnLeu: 2.736 ± 0.481
0.821GlnMet: 0.821 ± 0.674
3.01GlnAsn: 3.01 ± 0.442
1.368GlnPro: 1.368 ± 0.809
1.094GlnGln: 1.094 ± 0.745
1.368GlnArg: 1.368 ± 0.637
3.283GlnSer: 3.283 ± 0.867
2.462GlnThr: 2.462 ± 1.24
3.01GlnVal: 3.01 ± 1.059
0.821GlnTrp: 0.821 ± 0.438
1.368GlnTyr: 1.368 ± 0.507
0.0GlnXaa: 0.0 ± 0.0
Arg
3.01ArgAla: 3.01 ± 0.928
0.821ArgCys: 0.821 ± 0.712
2.189ArgAsp: 2.189 ± 0.793
3.557ArgGlu: 3.557 ± 0.901
3.283ArgPhe: 3.283 ± 1.251
2.736ArgGly: 2.736 ± 1.005
1.642ArgHis: 1.642 ± 0.803
5.472ArgIle: 5.472 ± 1.008
3.01ArgLys: 3.01 ± 1.059
3.557ArgLeu: 3.557 ± 0.952
1.094ArgMet: 1.094 ± 0.396
3.01ArgAsn: 3.01 ± 0.841
3.283ArgPro: 3.283 ± 0.945
1.915ArgGln: 1.915 ± 0.929
1.094ArgArg: 1.094 ± 0.388
2.736ArgSer: 2.736 ± 1.225
3.01ArgThr: 3.01 ± 1.113
3.283ArgVal: 3.283 ± 0.471
0.547ArgTrp: 0.547 ± 0.321
2.189ArgTyr: 2.189 ± 1.205
0.0ArgXaa: 0.0 ± 0.0
Ser
3.283SerAla: 3.283 ± 0.691
0.821SerCys: 0.821 ± 0.658
5.198SerAsp: 5.198 ± 0.465
4.378SerGlu: 4.378 ± 1.376
3.283SerPhe: 3.283 ± 0.937
5.198SerGly: 5.198 ± 1.374
2.189SerHis: 2.189 ± 0.527
4.925SerIle: 4.925 ± 1.596
4.651SerLys: 4.651 ± 0.852
7.934SerLeu: 7.934 ± 2.301
1.094SerMet: 1.094 ± 0.481
3.01SerAsn: 3.01 ± 0.705
4.925SerPro: 4.925 ± 1.636
1.915SerGln: 1.915 ± 1.317
4.651SerArg: 4.651 ± 0.557
6.84SerSer: 6.84 ± 1.532
5.746SerThr: 5.746 ± 1.466
6.293SerVal: 6.293 ± 1.34
2.189SerTrp: 2.189 ± 0.888
2.736SerTyr: 2.736 ± 0.31
0.0SerXaa: 0.0 ± 0.0
Thr
1.642ThrAla: 1.642 ± 0.378
1.368ThrCys: 1.368 ± 0.531
3.283ThrAsp: 3.283 ± 0.888
3.557ThrGlu: 3.557 ± 0.859
2.189ThrPhe: 2.189 ± 0.527
3.83ThrGly: 3.83 ± 0.51
1.642ThrHis: 1.642 ± 0.645
4.925ThrIle: 4.925 ± 1.404
3.01ThrLys: 3.01 ± 1.408
7.661ThrLeu: 7.661 ± 1.666
1.094ThrMet: 1.094 ± 0.388
3.01ThrAsn: 3.01 ± 0.81
2.462ThrPro: 2.462 ± 1.227
2.462ThrGln: 2.462 ± 0.687
2.462ThrArg: 2.462 ± 0.859
5.746ThrSer: 5.746 ± 1.242
4.104ThrThr: 4.104 ± 1.358
3.83ThrVal: 3.83 ± 0.43
1.094ThrTrp: 1.094 ± 0.643
2.736ThrTyr: 2.736 ± 0.988
0.0ThrXaa: 0.0 ± 0.0
Val
1.368ValAla: 1.368 ± 1.42
1.368ValCys: 1.368 ± 0.953
3.83ValAsp: 3.83 ± 0.98
2.189ValGlu: 2.189 ± 0.459
2.189ValPhe: 2.189 ± 0.459
3.283ValGly: 3.283 ± 0.771
2.462ValHis: 2.462 ± 0.722
3.283ValIle: 3.283 ± 1.222
3.01ValLys: 3.01 ± 1.056
5.746ValLeu: 5.746 ± 1.238
1.642ValMet: 1.642 ± 0.619
3.557ValAsn: 3.557 ± 1.167
3.01ValPro: 3.01 ± 1.341
4.104ValGln: 4.104 ± 1.059
3.01ValArg: 3.01 ± 0.905
3.83ValSer: 3.83 ± 0.884
5.198ValThr: 5.198 ± 1.111
3.283ValVal: 3.283 ± 1.092
0.274ValTrp: 0.274 ± 0.381
1.642ValTyr: 1.642 ± 0.353
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.274TrpCys: 0.274 ± 0.161
1.094TrpAsp: 1.094 ± 0.643
1.094TrpGlu: 1.094 ± 0.396
0.821TrpPhe: 0.821 ± 0.326
0.274TrpGly: 0.274 ± 0.161
0.547TrpHis: 0.547 ± 0.301
2.462TrpIle: 2.462 ± 1.031
1.094TrpLys: 1.094 ± 0.643
0.547TrpLeu: 0.547 ± 0.327
1.094TrpMet: 1.094 ± 0.603
1.915TrpAsn: 1.915 ± 1.124
0.821TrpPro: 0.821 ± 0.308
0.0TrpGln: 0.0 ± 0.0
1.094TrpArg: 1.094 ± 0.396
2.189TrpSer: 2.189 ± 0.888
1.642TrpThr: 1.642 ± 0.353
0.274TrpVal: 0.274 ± 0.161
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.915TyrAla: 1.915 ± 0.427
0.0TyrCys: 0.0 ± 0.0
3.557TyrAsp: 3.557 ± 0.624
1.094TyrGlu: 1.094 ± 0.435
1.642TyrPhe: 1.642 ± 0.599
2.189TyrGly: 2.189 ± 1.285
1.915TyrHis: 1.915 ± 0.544
2.736TyrIle: 2.736 ± 1.38
2.462TyrLys: 2.462 ± 1.082
3.283TyrLeu: 3.283 ± 1.222
1.094TyrMet: 1.094 ± 0.643
1.642TyrAsn: 1.642 ± 1.123
3.01TyrPro: 3.01 ± 0.599
2.189TyrGln: 2.189 ± 0.523
3.283TyrArg: 3.283 ± 1.577
1.915TyrSer: 1.915 ± 0.97
1.368TyrThr: 1.368 ± 0.689
1.915TyrVal: 1.915 ± 0.693
0.547TyrTrp: 0.547 ± 0.301
0.821TyrTyr: 0.821 ± 0.308
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3656 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski