Amino acid dipepetide frequency for Rhesus adenovirus 58

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.67AlaAla: 7.67 ± 1.74
0.719AlaCys: 0.719 ± 0.343
3.356AlaAsp: 3.356 ± 0.663
4.434AlaGlu: 4.434 ± 0.878
3.356AlaPhe: 3.356 ± 0.557
4.914AlaGly: 4.914 ± 0.615
1.318AlaHis: 1.318 ± 0.359
3.236AlaIle: 3.236 ± 0.64
1.318AlaLys: 1.318 ± 0.489
8.389AlaLeu: 8.389 ± 1.451
1.438AlaMet: 1.438 ± 0.424
3.595AlaAsn: 3.595 ± 0.773
6.232AlaPro: 6.232 ± 0.859
2.517AlaGln: 2.517 ± 0.597
5.034AlaArg: 5.034 ± 1.119
5.273AlaSer: 5.273 ± 0.718
3.955AlaThr: 3.955 ± 0.75
6.951AlaVal: 6.951 ± 0.926
0.959AlaTrp: 0.959 ± 0.271
2.517AlaTyr: 2.517 ± 0.487
0.0AlaXaa: 0.0 ± 0.0
Cys
1.678CysAla: 1.678 ± 0.542
0.839CysCys: 0.839 ± 0.312
0.959CysAsp: 0.959 ± 0.278
0.839CysGlu: 0.839 ± 0.291
0.599CysPhe: 0.599 ± 0.28
1.678CysGly: 1.678 ± 0.527
0.479CysHis: 0.479 ± 0.261
0.959CysIle: 0.959 ± 0.451
0.36CysLys: 0.36 ± 0.261
1.318CysLeu: 1.318 ± 0.504
0.36CysMet: 0.36 ± 0.196
0.24CysAsn: 0.24 ± 0.15
0.479CysPro: 0.479 ± 0.206
0.36CysGln: 0.36 ± 0.153
0.959CysArg: 0.959 ± 0.501
0.719CysSer: 0.719 ± 0.295
0.36CysThr: 0.36 ± 0.166
0.719CysVal: 0.719 ± 0.348
0.599CysTrp: 0.599 ± 0.303
1.318CysTyr: 1.318 ± 0.373
0.0CysXaa: 0.0 ± 0.0
Asp
3.116AspAla: 3.116 ± 0.636
0.599AspCys: 0.599 ± 0.259
2.277AspAsp: 2.277 ± 0.874
3.715AspGlu: 3.715 ± 0.63
2.517AspPhe: 2.517 ± 0.607
3.236AspGly: 3.236 ± 0.584
0.599AspHis: 0.599 ± 0.285
2.517AspIle: 2.517 ± 0.712
1.318AspLys: 1.318 ± 0.341
5.273AspLeu: 5.273 ± 0.884
1.198AspMet: 1.198 ± 0.267
2.517AspAsn: 2.517 ± 0.546
3.595AspPro: 3.595 ± 0.68
0.24AspGln: 0.24 ± 0.14
4.314AspArg: 4.314 ± 1.099
4.314AspSer: 4.314 ± 0.974
2.637AspThr: 2.637 ± 0.67
3.715AspVal: 3.715 ± 0.912
0.719AspTrp: 0.719 ± 0.186
1.558AspTyr: 1.558 ± 0.575
0.0AspXaa: 0.0 ± 0.0
Glu
4.434GluAla: 4.434 ± 0.982
0.839GluCys: 0.839 ± 0.373
3.595GluAsp: 3.595 ± 0.567
4.914GluGlu: 4.914 ± 1.112
2.277GluPhe: 2.277 ± 0.428
4.075GluGly: 4.075 ± 0.974
1.318GluHis: 1.318 ± 0.524
2.756GluIle: 2.756 ± 0.427
2.876GluLys: 2.876 ± 0.689
5.633GluLeu: 5.633 ± 0.774
1.798GluMet: 1.798 ± 0.496
2.756GluAsn: 2.756 ± 0.551
2.756GluPro: 2.756 ± 0.446
2.756GluGln: 2.756 ± 0.463
3.595GluArg: 3.595 ± 0.824
3.116GluSer: 3.116 ± 0.802
2.996GluThr: 2.996 ± 0.669
3.835GluVal: 3.835 ± 0.855
1.079GluTrp: 1.079 ± 0.328
1.079GluTyr: 1.079 ± 0.354
0.0GluXaa: 0.0 ± 0.0
Phe
2.637PheAla: 2.637 ± 0.343
0.839PheCys: 0.839 ± 0.3
3.116PheAsp: 3.116 ± 0.663
2.037PheGlu: 2.037 ± 0.536
1.438PhePhe: 1.438 ± 0.444
1.079PheGly: 1.079 ± 0.361
1.678PheHis: 1.678 ± 0.42
1.438PheIle: 1.438 ± 0.387
1.558PheLys: 1.558 ± 0.393
2.996PheLeu: 2.996 ± 0.671
1.438PheMet: 1.438 ± 0.317
2.876PheAsn: 2.876 ± 0.497
1.918PhePro: 1.918 ± 0.356
1.798PheGln: 1.798 ± 0.415
2.876PheArg: 2.876 ± 0.526
2.876PheSer: 2.876 ± 0.558
2.756PheThr: 2.756 ± 0.502
3.236PheVal: 3.236 ± 0.579
0.36PheTrp: 0.36 ± 0.214
1.558PheTyr: 1.558 ± 0.389
0.0PheXaa: 0.0 ± 0.0
Gly
5.872GlyAla: 5.872 ± 0.947
1.198GlyCys: 1.198 ± 0.437
2.637GlyAsp: 2.637 ± 0.516
2.876GlyGlu: 2.876 ± 0.521
1.918GlyPhe: 1.918 ± 0.432
4.674GlyGly: 4.674 ± 0.795
1.918GlyHis: 1.918 ± 0.591
2.157GlyIle: 2.157 ± 0.689
1.438GlyLys: 1.438 ± 0.566
5.633GlyLeu: 5.633 ± 1.078
1.079GlyMet: 1.079 ± 0.308
3.715GlyAsn: 3.715 ± 0.769
2.756GlyPro: 2.756 ± 0.697
2.157GlyGln: 2.157 ± 0.561
4.674GlyArg: 4.674 ± 0.796
5.872GlySer: 5.872 ± 0.668
3.116GlyThr: 3.116 ± 0.756
5.753GlyVal: 5.753 ± 0.949
0.839GlyTrp: 0.839 ± 0.248
1.798GlyTyr: 1.798 ± 0.445
0.0GlyXaa: 0.0 ± 0.0
His
1.918HisAla: 1.918 ± 0.459
0.599HisCys: 0.599 ± 0.29
0.719HisAsp: 0.719 ± 0.31
0.36HisGlu: 0.36 ± 0.182
0.719HisPhe: 0.719 ± 0.315
1.678HisGly: 1.678 ± 0.493
0.36HisHis: 0.36 ± 0.195
1.079HisIle: 1.079 ± 0.354
0.719HisLys: 0.719 ± 0.287
1.558HisLeu: 1.558 ± 0.48
0.36HisMet: 0.36 ± 0.234
1.198HisAsn: 1.198 ± 0.44
1.678HisPro: 1.678 ± 0.585
0.959HisGln: 0.959 ± 0.333
2.157HisArg: 2.157 ± 0.406
0.719HisSer: 0.719 ± 0.35
0.959HisThr: 0.959 ± 0.295
1.438HisVal: 1.438 ± 0.415
0.599HisTrp: 0.599 ± 0.352
0.36HisTyr: 0.36 ± 0.185
0.0HisXaa: 0.0 ± 0.0
Ile
2.996IleAla: 2.996 ± 0.567
0.959IleCys: 0.959 ± 0.33
1.558IleAsp: 1.558 ± 0.432
1.918IleGlu: 1.918 ± 0.478
0.959IlePhe: 0.959 ± 0.324
2.277IleGly: 2.277 ± 0.496
0.719IleHis: 0.719 ± 0.344
0.959IleIle: 0.959 ± 0.341
2.277IleLys: 2.277 ± 0.559
2.996IleLeu: 2.996 ± 0.575
1.198IleMet: 1.198 ± 0.313
2.037IleAsn: 2.037 ± 0.275
2.876IlePro: 2.876 ± 0.508
1.918IleGln: 1.918 ± 0.69
2.517IleArg: 2.517 ± 0.615
2.517IleSer: 2.517 ± 0.393
2.756IleThr: 2.756 ± 0.701
2.277IleVal: 2.277 ± 0.403
0.24IleTrp: 0.24 ± 0.163
1.558IleTyr: 1.558 ± 0.481
0.0IleXaa: 0.0 ± 0.0
Lys
1.918LysAla: 1.918 ± 0.479
0.839LysCys: 0.839 ± 0.271
1.438LysAsp: 1.438 ± 0.361
2.157LysGlu: 2.157 ± 0.643
2.037LysPhe: 2.037 ± 0.406
2.517LysGly: 2.517 ± 0.626
0.719LysHis: 0.719 ± 0.301
1.318LysIle: 1.318 ± 0.364
2.517LysLys: 2.517 ± 0.676
2.517LysLeu: 2.517 ± 0.95
1.438LysMet: 1.438 ± 0.565
1.678LysAsn: 1.678 ± 0.327
1.798LysPro: 1.798 ± 0.543
0.719LysGln: 0.719 ± 0.287
3.476LysArg: 3.476 ± 1.166
2.157LysSer: 2.157 ± 0.569
1.798LysThr: 1.798 ± 0.308
2.756LysVal: 2.756 ± 0.569
0.36LysTrp: 0.36 ± 0.204
0.479LysTyr: 0.479 ± 0.223
0.0LysXaa: 0.0 ± 0.0
Leu
8.03LeuAla: 8.03 ± 1.613
1.318LeuCys: 1.318 ± 0.414
4.674LeuAsp: 4.674 ± 1.082
5.872LeuGlu: 5.872 ± 1.061
2.037LeuPhe: 2.037 ± 0.552
5.513LeuGly: 5.513 ± 0.889
2.637LeuHis: 2.637 ± 0.681
2.037LeuIle: 2.037 ± 0.46
4.314LeuLys: 4.314 ± 0.69
8.988LeuLeu: 8.988 ± 1.385
2.996LeuMet: 2.996 ± 0.453
4.434LeuAsn: 4.434 ± 0.707
5.872LeuPro: 5.872 ± 0.869
5.753LeuGln: 5.753 ± 1.512
7.67LeuArg: 7.67 ± 1.137
5.872LeuSer: 5.872 ± 0.904
7.55LeuThr: 7.55 ± 1.386
6.232LeuVal: 6.232 ± 0.965
1.079LeuTrp: 1.079 ± 0.37
3.356LeuTyr: 3.356 ± 0.759
0.0LeuXaa: 0.0 ± 0.0
Met
2.876MetAla: 2.876 ± 0.589
0.12MetCys: 0.12 ± 0.112
1.438MetAsp: 1.438 ± 0.334
2.037MetGlu: 2.037 ± 0.641
0.959MetPhe: 0.959 ± 0.375
1.438MetGly: 1.438 ± 0.428
0.719MetHis: 0.719 ± 0.313
0.839MetIle: 0.839 ± 0.281
0.719MetLys: 0.719 ± 0.344
2.277MetLeu: 2.277 ± 0.653
0.719MetMet: 0.719 ± 0.307
1.558MetAsn: 1.558 ± 0.405
1.918MetPro: 1.918 ± 0.46
1.079MetGln: 1.079 ± 0.332
1.318MetArg: 1.318 ± 0.385
1.798MetSer: 1.798 ± 0.416
1.079MetThr: 1.079 ± 0.294
0.839MetVal: 0.839 ± 0.267
0.479MetTrp: 0.479 ± 0.232
1.318MetTyr: 1.318 ± 0.294
0.0MetXaa: 0.0 ± 0.0
Asn
2.637AsnAla: 2.637 ± 0.575
0.839AsnCys: 0.839 ± 0.334
2.996AsnAsp: 2.996 ± 0.705
2.037AsnGlu: 2.037 ± 0.481
2.756AsnPhe: 2.756 ± 0.683
3.476AsnGly: 3.476 ± 0.937
0.839AsnHis: 0.839 ± 0.328
2.397AsnIle: 2.397 ± 0.639
2.037AsnLys: 2.037 ± 0.659
3.236AsnLeu: 3.236 ± 0.723
2.157AsnMet: 2.157 ± 0.631
2.277AsnAsn: 2.277 ± 0.498
4.674AsnPro: 4.674 ± 0.7
1.798AsnGln: 1.798 ± 0.548
2.876AsnArg: 2.876 ± 0.553
4.075AsnSer: 4.075 ± 0.759
2.517AsnThr: 2.517 ± 0.645
2.996AsnVal: 2.996 ± 0.489
0.719AsnTrp: 0.719 ± 0.303
2.517AsnTyr: 2.517 ± 0.698
0.0AsnXaa: 0.0 ± 0.0
Pro
3.955ProAla: 3.955 ± 0.66
0.839ProCys: 0.839 ± 0.291
3.476ProAsp: 3.476 ± 0.624
4.314ProGlu: 4.314 ± 0.708
2.876ProPhe: 2.876 ± 0.762
4.314ProGly: 4.314 ± 0.636
1.438ProHis: 1.438 ± 0.373
1.678ProIle: 1.678 ± 0.364
1.438ProLys: 1.438 ± 0.204
6.951ProLeu: 6.951 ± 1.779
1.318ProMet: 1.318 ± 0.497
3.116ProAsn: 3.116 ± 0.524
6.592ProPro: 6.592 ± 1.481
2.397ProGln: 2.397 ± 0.51
4.914ProArg: 4.914 ± 1.126
5.393ProSer: 5.393 ± 0.676
4.195ProThr: 4.195 ± 0.527
5.393ProVal: 5.393 ± 1.136
0.839ProTrp: 0.839 ± 0.306
2.517ProTyr: 2.517 ± 0.497
0.0ProXaa: 0.0 ± 0.0
Gln
3.476GlnAla: 3.476 ± 0.644
0.36GlnCys: 0.36 ± 0.165
1.438GlnAsp: 1.438 ± 0.463
3.116GlnGlu: 3.116 ± 0.625
1.678GlnPhe: 1.678 ± 0.342
1.558GlnGly: 1.558 ± 0.409
0.599GlnHis: 0.599 ± 0.204
2.037GlnIle: 2.037 ± 0.314
1.438GlnLys: 1.438 ± 0.398
4.554GlnLeu: 4.554 ± 0.711
1.198GlnMet: 1.198 ± 0.386
2.157GlnAsn: 2.157 ± 0.87
3.595GlnPro: 3.595 ± 0.674
1.798GlnGln: 1.798 ± 0.482
2.996GlnArg: 2.996 ± 0.573
2.996GlnSer: 2.996 ± 0.566
2.876GlnThr: 2.876 ± 0.594
1.918GlnVal: 1.918 ± 0.377
0.479GlnTrp: 0.479 ± 0.252
1.198GlnTyr: 1.198 ± 0.227
0.0GlnXaa: 0.0 ± 0.0
Arg
6.112ArgAla: 6.112 ± 1.28
1.558ArgCys: 1.558 ± 0.472
3.476ArgAsp: 3.476 ± 0.876
3.595ArgGlu: 3.595 ± 0.798
3.116ArgPhe: 3.116 ± 0.514
6.472ArgGly: 6.472 ± 1.189
1.079ArgHis: 1.079 ± 0.445
2.157ArgIle: 2.157 ± 0.412
1.798ArgLys: 1.798 ± 0.358
6.232ArgLeu: 6.232 ± 0.962
0.959ArgMet: 0.959 ± 0.3
3.595ArgAsn: 3.595 ± 0.615
6.112ArgPro: 6.112 ± 1.274
4.554ArgGln: 4.554 ± 0.754
8.629ArgArg: 8.629 ± 3.036
4.314ArgSer: 4.314 ± 1.006
2.637ArgThr: 2.637 ± 0.456
5.153ArgVal: 5.153 ± 0.922
1.079ArgTrp: 1.079 ± 0.236
2.876ArgTyr: 2.876 ± 0.53
0.0ArgXaa: 0.0 ± 0.0
Ser
5.153SerAla: 5.153 ± 0.761
0.839SerCys: 0.839 ± 0.325
3.356SerAsp: 3.356 ± 0.712
3.715SerGlu: 3.715 ± 0.511
2.637SerPhe: 2.637 ± 0.482
4.674SerGly: 4.674 ± 0.715
0.959SerHis: 0.959 ± 0.308
3.236SerIle: 3.236 ± 0.525
2.037SerLys: 2.037 ± 0.432
9.228SerLeu: 9.228 ± 1.376
1.678SerMet: 1.678 ± 0.562
2.037SerAsn: 2.037 ± 0.444
3.356SerPro: 3.356 ± 0.633
2.756SerGln: 2.756 ± 0.441
5.753SerArg: 5.753 ± 0.85
5.872SerSer: 5.872 ± 0.846
4.674SerThr: 4.674 ± 0.696
4.075SerVal: 4.075 ± 0.745
1.079SerTrp: 1.079 ± 0.333
2.996SerTyr: 2.996 ± 0.777
0.0SerXaa: 0.0 ± 0.0
Thr
5.153ThrAla: 5.153 ± 0.916
0.959ThrCys: 0.959 ± 0.465
2.996ThrAsp: 2.996 ± 0.81
2.637ThrGlu: 2.637 ± 0.437
2.996ThrPhe: 2.996 ± 0.583
2.517ThrGly: 2.517 ± 0.607
0.959ThrHis: 0.959 ± 0.363
2.876ThrIle: 2.876 ± 0.87
1.678ThrLys: 1.678 ± 0.442
7.191ThrLeu: 7.191 ± 1.227
0.599ThrMet: 0.599 ± 0.232
3.835ThrAsn: 3.835 ± 1.276
4.674ThrPro: 4.674 ± 0.867
2.756ThrGln: 2.756 ± 0.633
2.517ThrArg: 2.517 ± 0.518
2.756ThrSer: 2.756 ± 0.526
3.476ThrThr: 3.476 ± 0.807
4.434ThrVal: 4.434 ± 0.64
1.079ThrTrp: 1.079 ± 0.448
2.637ThrTyr: 2.637 ± 0.742
0.0ThrXaa: 0.0 ± 0.0
Val
4.075ValAla: 4.075 ± 0.616
1.318ValCys: 1.318 ± 0.436
3.955ValAsp: 3.955 ± 0.647
4.554ValGlu: 4.554 ± 0.595
3.236ValPhe: 3.236 ± 0.578
2.637ValGly: 2.637 ± 0.57
1.198ValHis: 1.198 ± 0.456
2.517ValIle: 2.517 ± 0.613
2.876ValLys: 2.876 ± 0.657
5.753ValLeu: 5.753 ± 0.746
2.157ValMet: 2.157 ± 0.451
2.756ValAsn: 2.756 ± 0.457
4.314ValPro: 4.314 ± 0.607
2.756ValGln: 2.756 ± 0.506
5.753ValArg: 5.753 ± 1.03
4.674ValSer: 4.674 ± 0.696
5.393ValThr: 5.393 ± 0.758
4.434ValVal: 4.434 ± 0.812
0.479ValTrp: 0.479 ± 0.186
3.595ValTyr: 3.595 ± 0.649
0.0ValXaa: 0.0 ± 0.0
Trp
0.479TrpAla: 0.479 ± 0.214
0.0TrpCys: 0.0 ± 0.0
0.719TrpAsp: 0.719 ± 0.223
1.558TrpGlu: 1.558 ± 0.472
0.599TrpPhe: 0.599 ± 0.282
1.318TrpGly: 1.318 ± 0.336
0.0TrpHis: 0.0 ± 0.0
0.479TrpIle: 0.479 ± 0.227
0.719TrpLys: 0.719 ± 0.258
1.198TrpLeu: 1.198 ± 0.425
0.12TrpMet: 0.12 ± 0.125
1.318TrpAsn: 1.318 ± 0.407
0.719TrpPro: 0.719 ± 0.223
0.24TrpGln: 0.24 ± 0.188
1.198TrpArg: 1.198 ± 0.437
1.558TrpSer: 1.558 ± 0.333
0.959TrpThr: 0.959 ± 0.295
0.24TrpVal: 0.24 ± 0.182
0.12TrpTrp: 0.12 ± 0.131
0.24TrpTyr: 0.24 ± 0.173
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.996TyrAla: 2.996 ± 0.478
0.24TyrCys: 0.24 ± 0.14
1.798TyrAsp: 1.798 ± 0.438
1.798TyrGlu: 1.798 ± 0.484
1.798TyrPhe: 1.798 ± 0.51
2.037TyrGly: 2.037 ± 0.534
0.599TyrHis: 0.599 ± 0.37
0.839TyrIle: 0.839 ± 0.311
1.198TyrLys: 1.198 ± 0.296
4.314TyrLeu: 4.314 ± 0.645
1.198TyrMet: 1.198 ± 0.371
2.157TyrAsn: 2.157 ± 0.548
2.037TyrPro: 2.037 ± 0.509
2.157TyrGln: 2.157 ± 0.542
2.277TyrArg: 2.277 ± 0.434
3.236TyrSer: 3.236 ± 0.684
2.037TyrThr: 2.037 ± 0.293
2.157TyrVal: 2.157 ± 0.57
0.599TyrTrp: 0.599 ± 0.212
0.599TyrTyr: 0.599 ± 0.258
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 23 proteins (8345 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski